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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2393931
log Bayes Factor = 14.7422
Chromosome 6   position 27,353,114  (GRCh37) Explore rs2393931 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90 Intestinal malabsorption
0.000 0.688 0.312
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.743 0.257
K90.3 Pancreatic steatorrhoea
0.000 0.776 0.224
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.776 0.224
K90.1 Tropical sprue
0.000 0.776 0.224
K90.8 Other intestinal malabsorption
0.000 0.785 0.215
E10 Insulin-dependent diabetes mellitus
0.000 0.794 0.206
E10.9 Without complications
0.000 0.795 0.205
E10.4 With neurological complications
0.000 0.812 0.188
E10.5 With peripheral circulatory complications
0.000 0.813 0.187
E10.6 With other specified complications
0.000 0.817 0.183
E10.8 With unspecified complications
0.000 0.826 0.174
E83 Disorders of mineral metabolism
0.000 0.832 0.168
E10.1 With ketoacidosis
0.000 0.842 0.158
E10.2 With renal complications
0.000 0.846 0.154
E10-E14 Diabetes mellitus
0.000 0.850 0.150
E10.7 With multiple complications
0.000 0.852 0.148
E10.0 With coma
0.000 0.866 0.134
E13 Other specified diabetes mellitus
0.000 0.872 0.127
E10.3 With ophthalmic complications
0.000 0.875 0.125
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.880 0.120
E83.8 Other disorders of mineral metabolism
0.000 0.880 0.120
E83.2 Disorders of zinc metabolism
0.000 0.880 0.120
E83.0 Disorders of copper metabolism
0.000 0.880 0.120
E70-E90 Metabolic disorders
0.000 0.887 0.113
E14 Unspecified diabetes mellitus
0.000 0.887 0.113
E13.9 Without complications
0.000 0.888 0.112
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.889 0.111
E12 Malnutrition-related diabetes mellitus
0.000 0.892 0.108
E14.3 With ophthalmic complications
0.000 0.892 0.108
E88 Other metabolic disorders
0.000 0.905 0.095
K90.9 Intestinal malabsorption, unspecified
0.001 0.906 0.094
E40-E46 Malnutrition
0.000 0.906 0.094
E13.8 With unspecified complications
0.000 0.908 0.091
E13.7 With multiple complications
0.000 0.908 0.091
E13.6 With other specified complications
0.000 0.908 0.091
E13.5 With peripheral circulatory complications
0.000 0.908 0.091
E13.4 With neurological complications
0.000 0.908 0.091
E13.2 With renal complications
0.000 0.908 0.091
E13.1 With ketoacidosis
0.000 0.908 0.091
E13.0 With coma
0.000 0.908 0.091
E85 Amyloidosis
0.000 0.908 0.092
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.909 0.091
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.910 0.090
E13.3 With ophthalmic complications
0.000 0.910 0.089
E14.5 With peripheral circulatory complications
0.000 0.916 0.084
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.917 0.083
E84 Cystic fibrosis
0.000 0.919 0.081
E77 Disorders of glycoprotein metabolism
0.000 0.919 0.081
E76 Disorders of glycosaminoglycan metabolism
0.000 0.919 0.081
E72 Other disorders of amino-acid metabolism
0.000 0.919 0.081
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.919 0.081
E70 Disorders of aromatic amino-acid metabolism
0.000 0.919 0.081
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.919 0.081
E14.7 With multiple complications
0.000 0.919 0.081
E14.6 With other specified complications
0.000 0.919 0.081
E14.2 Withrenal complications
0.000 0.919 0.081
E14.0 With coma
0.000 0.919 0.081
E46 Unspecified protein-energy malnutrition
0.000 0.919 0.081
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.919 0.081
E14.4 With neurological complications
0.000 0.922 0.078
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.922 0.078
E12.9 Without complications
0.000 0.922 0.077
E12.8 With unspecified complications
0.000 0.922 0.077
E12.7 With multiple complications
0.000 0.922 0.077
E12.6 With other specified complications
0.000 0.922 0.077
E12.5 With peripheral circulatory complications
0.000 0.922 0.077
E12.4 With neurological complications
0.000 0.922 0.077
E12.3 With ophthalmic complications
0.000 0.922 0.077
E12.2 With renal complications
0.000 0.922 0.077
E12.1 With ketoacidosis
0.000 0.922 0.077
E12.0 With coma
0.000 0.922 0.077
E16 Other disorders of pancreatic internal secretion
0.000 0.923 0.077
E85.9 Amyloidosis, unspecified
0.000 0.923 0.077
E65-E68 Obesity and other hyperalimentation
0.000 0.925 0.075
E79 Disorders of purine and pyrimidine metabolism
0.000 0.926 0.073
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.927 0.073
E88.8 Other specified metabolic disorders
0.000 0.927 0.073
E89.0 Postprocedural hypothyroidism
0.000 0.927 0.073
E83.3 Disorders of phosphorus metabolism
0.000 0.927 0.072
E89.2 Postprocedural hypoparathyroidism
0.000 0.928 0.072
E88.2 Lipomatosis, not elsewhere classified
0.000 0.928 0.072
E83.4 Disorders of magnesium metabolism
0.000 0.928 0.072
E16.2 Hypoglycaemia, unspecified
0.000 0.930 0.070
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.930 0.070
E85.4 Organ-limited amyloidosis
0.000 0.931 0.069
E88.3 Tumour lysis syndrome
0.000 0.931 0.069
E14.1 With ketoacidosis
0.000 0.931 0.069
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.933 0.067
E45 Retarded development following protein-energy malnutrition
0.000 0.933 0.067
E43 Unspecified severe protein-energy malnutrition
0.000 0.933 0.067
E42 Marasmic kwashiorkor
0.000 0.933 0.067
E41 Nutritional marasmus
0.000 0.933 0.067
E40 Kwashiorkor
0.000 0.933 0.067
E89.4 Postprocedural ovarian failure
0.000 0.933 0.067
E14.8 With unspecified complications
0.000 0.933 0.067
E85.8 Other amyloidosis
0.000 0.934 0.066
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.934 0.066
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.934 0.066
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.934 0.066
E15 Nondiabetic hypoglycaemic coma
0.000 0.934 0.065
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.935 0.064
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.935 0.064
E89.5 Postprocedural testicular hypofunction
0.000 0.935 0.064
E89.1 Postprocedural hypoinsulinaemia
0.000 0.935 0.064
E65 Localised adiposity
0.000 0.936 0.064
E74 Other disorders of carbohydrate metabolism
0.000 0.936 0.064
E88.9 Metabolic disorder, unspecified
0.000 0.936 0.064
E80.4 Gilbert's syndrome
0.000 0.938 0.062
E85.3 Secondary systemic amyloidosis
0.000 0.939 0.061
E75.5 Other lipid storage disorders
0.000 0.939 0.061
E73 Lactose intolerance
0.000 0.940 0.059
E75.6 Lipid storage disorder, unspecified
0.000 0.940 0.059
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.940 0.059
E75.3 Sphingolipidosis, unspecified
0.000 0.940 0.059
E75.2 Other sphingolipidosis
0.000 0.940 0.059
E75.1 Other gangliosidosis
0.000 0.940 0.059
E75.0 GM2 gangliosidosis
0.000 0.940 0.059
E11 Non-insulin-dependent diabetes mellitus
0.000 0.941 0.059
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.942 0.058
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.942 0.058
E70.3 Albinism
0.000 0.942 0.058
E70.2 Disorders of tyrosine metabolism
0.000 0.942 0.058
E70.1 Other hyperphenylalaninaemias
0.000 0.942 0.058
E70.0 Classical phenylketonuria
0.000 0.942 0.058
E71.3 Disorders of fatty-acid metabolism
0.000 0.942 0.058
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.942 0.058
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.942 0.058
E71.0 Maple-syrup-urine disease
0.000 0.942 0.058
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.942 0.058
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.942 0.058
E72.5 Disorders of glycine metabolism
0.000 0.942 0.058
E72.4 Disorders of ornithine metabolism
0.000 0.942 0.058
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.942 0.058
E72.2 Disorders of urea cycle metabolism
0.000 0.942 0.058
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.942 0.058
E72.0 Disorders of amino-acid transport
0.000 0.942 0.058
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.942 0.058
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.942 0.058
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.942 0.058
E76.2 Other mucopolysaccharidoses
0.000 0.942 0.058
E76.1 Mucopolysaccharidosis, type II
0.000 0.942 0.058
E76.0 Mucopolysaccharidosis, type I
0.000 0.942 0.058
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.942 0.058
E77.8 Other disorders of glycoprotein metabolism
0.000 0.942 0.058
E77.1 Defects in glycoprotein degradation
0.000 0.942 0.058
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.942 0.058
E84.9 Cystic fibrosis, unspecified
0.000 0.942 0.058
E84.8 Cystic fibrosis with other manifestations
0.000 0.942 0.058
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.942 0.058
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.942 0.058
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.942 0.058
E80.5 Crigler-Najjar syndrome
0.000 0.942 0.058
E80.3 Defects of catalase and peroxydase
0.000 0.942 0.058
E80.1 Porphyria cutanea tarda
0.000 0.942 0.058
E80.0 Hereditary erythropoietic porphyria
0.000 0.942 0.058
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.943 0.057
E80.2 Other porphyria
0.000 0.944 0.056
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.945 0.055
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.945 0.055
E16.4 Abnormal secretion of gastrin
0.000 0.945 0.055
E16.3 Increased secretion of glucagon
0.000 0.945 0.055
E80.6 Other disorders of bilirubin metabolism
0.000 0.945 0.055
E67 Other hyperalimentation
0.000 0.946 0.054
E68 Sequelae of hyperalimentation
0.000 0.946 0.054
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.947 0.053
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.947 0.053
E79.1 Lesch-Nyhan syndrome
0.000 0.947 0.053
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.948 0.052
E00-E07 Disorders of thyroid gland
0.000 0.948 0.052
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.949 0.051
E11.5 With peripheral circulatory complications
0.000 0.951 0.049
E44.1 Mild protein-energy malnutrition
0.000 0.951 0.048
E44.0 Moderate protein-energy malnutrition
0.000 0.951 0.048
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.954 0.046
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.954 0.046
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.954 0.046
E74.2 Disorders of galactose metabolism
0.000 0.954 0.046
E74.1 Disorders of fructose metabolism
0.000 0.954 0.046
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.955 0.045
E11.0 With coma
0.000 0.955 0.045
E11.8 With unspecified complications
0.000 0.956 0.044
E11.1 With ketoacidosis
0.000 0.957 0.043
E73.8 Other lactose intolerance
0.000 0.957 0.043
E73.1 Secondary lactase deficiency
0.000 0.957 0.043
E73.0 Congenital lactase deficiency
0.000 0.957 0.043
E74.0 Glycogen storage disease
0.000 0.957 0.042
E11.7 With multiple complications
0.000 0.958 0.042
E11.2 With renal complications
0.000 0.958 0.042
E78.4 Other hyperlipidaemia
0.000 0.958 0.042
E16.1 Other hypoglycaemia
0.000 0.958 0.042
E50-E64 Other nutritional deficiencies
0.000 0.959 0.041
E83.5 Disorders of calcium metabolism
0.000 0.960 0.040
E89.3 Postprocedural hypopituitarism
0.000 0.961 0.039
E78.6 Lipoprotein deficiency
0.000 0.961 0.039
E07 Other disorders of thyroid
0.000 0.961 0.039
E67.8 Other specified hyperalimentation
0.000 0.961 0.039
E67.3 Hypervitaminosis D
0.000 0.961 0.039
E67.2 Megavitamin-B6 syndrome
0.000 0.961 0.039
E67.1 Hypercarotenaemia
0.000 0.961 0.039
E67.0 Hypervitaminosis A
0.000 0.961 0.039
E06 Thyroiditis
0.000 0.961 0.039
E11.4 With neurological complications
0.000 0.961 0.039
E11.6 With other specified complications
0.000 0.962 0.038
E04 Other non-toxic goitre
0.000 0.962 0.038
E78.3 Hyperchylomicronaemia
0.000 0.963 0.037
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.963 0.037
E00 Congenital iodine-deficiency syndrome
0.000 0.963 0.037
E14.9 Without complications
0.000 0.963 0.037
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.965 0.035
E78.1 Pure hyperglyceridaemia
0.000 0.965 0.035
E78.2 Mixed hyperlipidaemia
0.000 0.965 0.035
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.966 0.034
E03 Other hypothyroidism
0.000 0.966 0.034
E07.9 Disorder of thyroid, unspecified
0.000 0.968 0.032
E04.9 Non-toxic goitre, unspecified
0.000 0.968 0.032
E06.3 Autoimmune thyroiditis
0.000 0.968 0.032
E87.3 Alkalosis
0.000 0.968 0.032
E03.8 Other specified hypothyroidism
0.000 0.969 0.031
E20-E35 Disorders of other endocrine glands
0.000 0.970 0.030
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.970 0.029
E63 Other nutritional deficiencies
0.000 0.970 0.029
E56 Other vitamin deficiencies
0.000 0.970 0.029
E50 Vitamin A deficiency
0.000 0.970 0.029
E60 Dietary zinc deficiency
0.000 0.970 0.029
E59 Dietary selenium deficiency
0.000 0.970 0.029
E54 Ascorbic acid deficiency
0.000 0.970 0.029
E52 Niacin deficiency [pellagra]
0.000 0.970 0.029
E58 Dietary calcium deficiency
0.000 0.971 0.029
E04.0 Non-toxic diffuse goitre
0.000 0.971 0.029
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.971 0.028
E51 Thiamine deficiency
0.000 0.971 0.028
E07.1 Dyshormogenetic goitre
0.000 0.972 0.028
E07.0 Hypersecretion of calcitonin
0.000 0.972 0.028
E11.3 With ophthalmic complications
0.000 0.972 0.028
E87.0 Hyperosmolality and hypernatraemia
0.000 0.972 0.028
E06.5 Other chronic thyroiditis
0.000 0.972 0.028
E06.4 Drug-induced thyroiditis
0.000 0.972 0.028
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.972 0.028
E06.1 Subacute thyroiditis
0.000 0.972 0.028
E06.0 Acute thyroiditis
0.000 0.972 0.028
E53 Deficiency of other B group vitamins
0.000 0.972 0.028
E04.8 Other specified non-toxic goitre
0.000 0.973 0.027
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.973 0.027
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.973 0.027
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.973 0.027
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.973 0.027
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.973 0.027
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.973 0.027
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.973 0.027
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.973 0.027
E04.2 Non-toxic multinodular goitre
0.000 0.975 0.025
E07.8 Other specified disorders of thyroid
0.000 0.975 0.025
E87.7 Fluid overload
0.000 0.975 0.025
E87.4 Mixed disorder of acid-base balance
0.000 0.975 0.025
E06.9 Thyroiditis, unspecified
0.000 0.975 0.024
E03.5 Myxoedema coma
0.000 0.975 0.024
E03.4 Atrophy of thyroid (acquired)
0.000 0.975 0.024
E03.3 Postinfectious hypothyroidism
0.000 0.975 0.024
E03.1 Congenital hypothyroidism without goitre
0.000 0.975 0.024
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.975 0.024
E66 Obesity
0.000 0.976 0.024
E87.2 Acidosis
0.000 0.976 0.024
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.976 0.024
R31 Unspecified haematuria
0.024 0.976 0.000
E28 Ovarian dysfunction
0.000 0.977 0.023
E55 Vitamin D deficiency
0.000 0.977 0.023
E26 Hyperaldosteronism
0.000 0.977 0.023
E78.8 Other disorders of lipoprotein metabolism
0.000 0.978 0.022
E20 Hypoparathyroidism
0.000 0.978 0.022
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.978 0.022
E73.9 Lactose intolerance, unspecified
0.001 0.978 0.021
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.978 0.022
E32 Diseases of thymus
0.000 0.978 0.022
E31 Polyglandular dysfunction
0.000 0.978 0.022
E30 Disorders of puberty, not elsewhere classified
0.000 0.978 0.022
E25 Adrenogenital disorders
0.000 0.978 0.022
E29 Testicular dysfunction
0.000 0.978 0.021
E23 Hypofunction and other disorders of pituitary gland
0.000 0.978 0.021
E50.9 Vitamin A deficiency, unspecified
0.000 0.979 0.021
E50.8 Other manifestations of vitamin A deficiency
0.000 0.979 0.021
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.979 0.021
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.979 0.021
E50.5 Vitamin A deficiency with night blindness
0.000 0.979 0.021
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.979 0.021
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.979 0.021
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.979 0.021
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.979 0.021
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.979 0.021
E56.9 Vitamin deficiency, unspecified
0.000 0.979 0.021
E56.8 Deficiency of other vitamins
0.000 0.979 0.021
E56.1 Deficiency of vitamin K
0.000 0.979 0.021
E56.0 Deficiency of vitamin E
0.000 0.979 0.021
E63.9 Nutritional deficiency, unspecified
0.000 0.979 0.021
E63.8 Other specified nutritional deficiencies
0.000 0.979 0.021
E63.1 Imbalance of constituents of food intake
0.000 0.979 0.021
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.979 0.021
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.979 0.021
E64.8 Sequelae of other nutritional deficiencies
0.000 0.979 0.021
E64.3 Sequelae of rickets
0.000 0.979 0.021
E64.2 Sequelae of vitamin C deficiency
0.000 0.979 0.021
E64.1 Sequelae of vitamin A deficiency
0.000 0.979 0.021
E64.0 Sequelae of protein-energy malnutrition
0.000 0.979 0.021
E28.2 Polycystic ovarian syndrome
0.000 0.979 0.021
E51.9 Thiamine deficiency, unspecified
0.000 0.979 0.020
E51.8 Other manifestations of thiamine deficiency
0.000 0.979 0.020
E51.1 Beriberi
0.000 0.979 0.020
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.979 0.020
K90-K93 Other diseases of the digestive system
0.000 0.980 0.020
E53.1 Pyridoxine deficiency
0.000 0.980 0.020
E53.0 Riboflavin deficiency
0.000 0.980 0.020
E23.2 Diabetes insipidus
0.000 0.980 0.020
E53.9 Vitamin B deficiency, unspecified
0.000 0.980 0.020
E87.5 Hyperkalaemia
0.000 0.980 0.020
E04.1 Non-toxic single thyroid nodule
0.000 0.980 0.020
E34 Other endocrine disorders
0.000 0.980 0.020
E24 Cushing's syndrome
0.000 0.980 0.020
E51.2 Wernicke's encephalopathy
0.000 0.980 0.019
E53.8 Deficiency of other specified B group vitamins
0.000 0.981 0.019
E27 Other disorders of adrenal gland
0.000 0.982 0.018
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.982 0.018
E66.1 Drug-induced obesity
0.000 0.982 0.017
E27.1 Primary adrenocortical insufficiency
0.000 0.982 0.018
E26.0 Primary hyperaldosteronism
0.000 0.983 0.017
E28.9 Ovarian dysfunction, unspecified
0.000 0.983 0.017
E28.8 Other ovarian dysfunction
0.000 0.983 0.017
E28.1 Androgen excess
0.000 0.983 0.017
E28.0 Oestrogen excess
0.000 0.983 0.017
E66.0 Obesity due to excess calories
0.000 0.983 0.017
E20.9 Hypoparathyroidism, unspecified
0.000 0.983 0.017
E05.8 Other thyrotoxicosis
0.000 0.983 0.017
E55.0 Rickets, active
0.000 0.983 0.017
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.983 0.017
E24.2 Drug-induced Cushing's syndrome
0.000 0.983 0.016
E26.9 Hyperaldosteronism, unspecified
0.000 0.983 0.016
E26.8 Other hyperaldosteronism
0.000 0.983 0.016
E26.1 Secondary hyperaldosteronism
0.000 0.983 0.016
E20.8 Other hypoparathyroidism
0.000 0.984 0.016
E20.1 Pseudohypoparathyroidism
0.000 0.984 0.016
E20.0 Idiopathic hypoparathyroidism
0.000 0.984 0.016
E05.5 Thyroid crisis or storm
0.000 0.984 0.016
E05.4 Thyrotoxicosis factitia
0.000 0.984 0.016
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.984 0.016
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.984 0.016
E61 Deficiency of other nutrient elements
0.001 0.984 0.015
E25.9 Adrenogenital disorder, unspecified
0.000 0.984 0.016
E25.8 Other adrenogenital disorders
0.000 0.984 0.016
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.984 0.016
E30.9 Disorder of puberty, unspecified
0.000 0.984 0.016
E30.8 Other disorders of puberty
0.000 0.984 0.016
E30.1 Precocious puberty
0.000 0.984 0.016
E30.0 Delayed puberty
0.000 0.984 0.016
E31.9 Polyglandular dysfunction, unspecified
0.000 0.984 0.016
E31.8 Other polyglandular dysfunction
0.000 0.984 0.016
E31.1 Polyglandular hyperfunction
0.000 0.984 0.016
E31.0 Autoimmune polyglandular failure
0.000 0.984 0.016
E32.9 Disease of thymus, unspecified
0.000 0.984 0.016
E32.8 Other diseases of thymus
0.000 0.984 0.016
E32.1 Abscess of thymus
0.000 0.984 0.016
E32.0 Persistent hyperplasia of thymus
0.000 0.984 0.016
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.984 0.016
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.984 0.016
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.984 0.016
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.984 0.016
E23.1 Drug-induced hypopituitarism
0.000 0.984 0.016
E29.9 Testicular dysfunction, unspecified
0.000 0.984 0.016
E29.8 Other testicular dysfunction
0.000 0.984 0.016
E29.0 Testicular hyperfunction
0.000 0.984 0.016
E29.1 Testicular hypofunction
0.000 0.985 0.015
E23.7 Disorder of pituitary gland, unspecified
0.000 0.985 0.015
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.985 0.015
E34.5 Androgen resistance syndrome
0.000 0.986 0.014
E34.4 Constitutional tall stature
0.000 0.986 0.014
E34.3 Short stature, not elsewhere classified
0.000 0.986 0.014
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.986 0.014
E34.1 Other hypersecretion of intestinal hormones
0.000 0.986 0.014
E24.8 Other Cushing's syndrome
0.000 0.986 0.014
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.986 0.014
E24.3 Ectopic ACTH syndrome
0.000 0.986 0.014
E24.1 Nelson's syndrome
0.000 0.986 0.014
E34.9 Endocrine disorder, unspecified
0.000 0.986 0.014
E34.8 Other specified endocrine disorders
0.000 0.986 0.014
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.986 0.014
E23.6 Other disorders of pituitary gland
0.000 0.986 0.014
C71.2 Temporal lobe
0.014 0.986 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.987 0.013
E27.0 Other adrenocortical overactivity
0.000 0.987 0.013
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.987 0.013
E86 Volume depletion
0.000 0.987 0.013
E34.0 Carcinoid syndrome
0.000 0.987 0.013
C71 Malignant neoplasm of brain
0.013 0.987 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.987 0.013
E24.0 Pituitary-dependent Cushing's disease
0.000 0.987 0.013
C71.9 Brain, unspecified
0.013 0.987 0.000
E61.9 Deficiency of nutrient element, unspecified
0.001 0.988 0.011
E61.8 Deficiency of other specified nutrient elements
0.001 0.988 0.011
E61.7 Deficiency of multiple nutrient elements
0.001 0.988 0.011
E61.6 Vanadium deficiency
0.001 0.988 0.011
E61.5 Molybdenum deficiency
0.001 0.988 0.011
E61.4 Chromium deficiency
0.001 0.988 0.011
E61.3 Manganese deficiency
0.001 0.988 0.011
E61.0 Copper deficiency
0.001 0.988 0.011
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.989 0.011
E28.3 Primary ovarian failure
0.000 0.989 0.011
C71.3 Parietal lobe
0.011 0.989 0.000
C71.1 Frontal lobe
0.011 0.989 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.989 0.011
K93.1 Megacolon in Chagas' disease
0.000 0.989 0.011
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.989 0.011
E27.2 Addisonian crisis
0.000 0.989 0.010
M41.9 Scoliosis, unspecified
0.010 0.990 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.990 0.010
M41.96 Scoliosis, unspecified (Lumbar region)
0.010 0.990 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.990 0.010
C71.7 Brain stem
0.010 0.990 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.990 0.010
E21.2 Other hyperparathyroidism
0.000 0.990 0.010
E21.3 Hyperparathyroidism, unspecified
0.000 0.990 0.010
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.010 0.990 0.000
C71.6 Cerebellum
0.010 0.990 0.000
C71.5 Cerebral ventricle
0.010 0.990 0.000
C71.0 Cerebrum, except lobes and ventricles
0.010 0.990 0.000
E22 Hyperfunction of pituitary gland
0.000 0.990 0.009
M41.94 Scoliosis, unspecified (Thoracic region)
0.010 0.990 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.010 0.990 0.000
C71.8 Overlapping lesion of brain
0.009 0.990 0.000
E61.2 Magnesium deficiency
0.001 0.991 0.008
G31.8 Other specified degenerative diseases of nervous system
0.000 0.991 0.009
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.991 0.009
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.991 0.009
E27.8 Other specified disorders of adrenal gland
0.000 0.991 0.009
G44.2 Tension-type headache
0.008 0.992 0.000
C71.4 Occipital lobe
0.008 0.992 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.992 0.008
E27.9 Disorder of adrenal gland, unspecified
0.000 0.992 0.008
E23.0 Hypopituitarism
0.000 0.992 0.008
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.008 0.992 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.008 0.992 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.008 0.992 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.008 0.992 0.000
G31.0 Circumscribed brain atrophy
0.000 0.992 0.008
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.008 0.992 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.008 0.992 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.993 0.007
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.993 0.007
E22.8 Other hyperfunction of pituitary gland
0.000 0.993 0.007
M79.10 Myalgia (Multiple sites)
0.007 0.993 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.007 0.993 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.000 0.993 0.007
C69 Malignant neoplasm of eye and adnexa
0.007 0.993 0.000
E22.1 Hyperprolactinaemia
0.000 0.994 0.006
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.994 0.006
C70 Malignant neoplasm of meninges
0.006 0.994 0.000
N04.9 Unspecified
0.000 0.994 0.006
C69.9 Eye, unspecified
0.006 0.994 0.000
E87.6 Hypokalaemia
0.000 0.994 0.006
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.005 0.994 0.000
E66.9 Obesity, unspecified
0.000 0.994 0.006
C69.3 Choroid
0.005 0.995 0.000
C69.8 Overlapping lesion of eye and adnexa
0.005 0.995 0.000
C69.5 Lachrymal gland and duct
0.005 0.995 0.000
C69.4 Ciliary body
0.005 0.995 0.000
C69.2 Retina
0.005 0.995 0.000
C69.1 Cornea
0.005 0.995 0.000
C70.0 Cerebral meninges
0.005 0.995 0.000
M41 Scoliosis
0.005 0.995 0.000
C69.6 Orbit
0.005 0.995 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.995 0.005
G30-G32 Other degenerative diseases of the nervous system
0.000 0.995 0.005
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.005 0.995 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.005 0.995 0.000
C69.0 Conjunctiva
0.005 0.995 0.000
E21.0 Primary hyperparathyroidism
0.000 0.995 0.005
G31.2 Degeneration of nervous system due to alcohol
0.000 0.995 0.005
N50.1 Vascular disorders of male genital organs
0.000 0.995 0.005
E22.0 Acromegaly and pituitary gigantism
0.000 0.995 0.004
G54.9 Nerve root and plexus disorder, unspecified
0.005 0.995 0.000
C70.9 Meninges, unspecified
0.004 0.995 0.000
C70.1 Spinal meninges
0.004 0.995 0.000
G30 Alzheimer's disease
0.000 0.995 0.005
M67.8 Other specified disorders of synovium and tendon
0.000 0.995 0.005
E61.1 Iron deficiency
0.001 0.995 0.003
M79.19 Myalgia (Site unspecified)
0.005 0.995 0.000
M79.1 Myalgia
0.004 0.996 0.000
G30.0 Alzheimer's disease with early onset
0.000 0.996 0.004
C72.9 Central nervous system, unspecified
0.004 0.996 0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.004 0.996 0.000
C72.5 Other and unspecified cranial nerves
0.004 0.996 0.000
C72.4 Acoustic nerve
0.004 0.996 0.000
C72.3 Optic nerve
0.004 0.996 0.000
C72.2 Olfactory nerve
0.004 0.996 0.000
C72.1 Cauda equina
0.004 0.996 0.000
R52.1 Chronic intractable pain
0.004 0.996 0.000
G44 Other headache syndromes
0.004 0.996 0.000
C72.0 Spinal cord
0.004 0.996 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.000 0.996 0.004
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.996 0.004
G30.9 Alzheimer's disease, unspecified
0.000 0.996 0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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