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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2394159
log Bayes Factor = 21.8579
Chromosome 6   position 29,702,679  (GRCh37) Explore rs2394159 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.027 0.973
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.174 0.826
G37 Other demyelinating diseases of central nervous system
0.000 0.216 0.784
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.290 0.710
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.295 0.705
G36 Other acute disseminated demyelination
0.000 0.428 0.571
G37.5 Concentric sclerosis [Balo]
0.000 0.438 0.562
G37.4 Subacute necrotising myelitis
0.000 0.438 0.562
G37.2 Central pontine myelinolysis
0.000 0.438 0.562
G37.1 Central demyelination of corpus callosum
0.000 0.438 0.562
G37.0 Diffuse sclerosis
0.000 0.438 0.562
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.464 0.536
G36.9 Acute disseminated demyelination, unspecified
0.000 0.590 0.410
G36.8 Other specified acute disseminated demyelination
0.000 0.590 0.410
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.590 0.410
G36.0 Neuromyelitis optica [Devic]
0.000 0.611 0.389
K90 Intestinal malabsorption
0.000 0.777 0.223
M35.0 Sicca syndrome [Sjogren]
0.000 0.791 0.209
Chapter VI Diseases of the nervous system
0.000 0.819 0.181
G40-G47 Episodic and paroxysmal disorders
0.000 0.827 0.173
E83 Disorders of mineral metabolism
0.000 0.828 0.172
G30-G32 Other degenerative diseases of the nervous system
0.000 0.834 0.166
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.835 0.165
G40 Epilepsy
0.000 0.836 0.164
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.837 0.163
E05.9 Thyrotoxicosis, unspecified
0.000 0.837 0.163
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.840 0.160
K90.3 Pancreatic steatorrhoea
0.000 0.840 0.160
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.840 0.160
K90.1 Tropical sprue
0.000 0.840 0.160
K90.8 Other intestinal malabsorption
0.000 0.841 0.159
G47 Sleep disorders
0.000 0.843 0.157
G47.9 Sleep disorder, unspecified
0.000 0.844 0.156
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.846 0.154
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.000 0.850 0.150
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.000 0.851 0.149
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.000 0.852 0.148
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.855 0.145
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.856 0.144
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.858 0.142
K51 Ulcerative colitis
0.142 0.858 0.000
K51.2 Ulcerative (chronic) proctitis
0.141 0.859 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.861 0.139
K51.9 Ulcerative colitis, unspecified
0.137 0.863 0.000
E06 Thyroiditis
0.000 0.863 0.137
E06.3 Autoimmune thyroiditis
0.000 0.865 0.135
E00-E07 Disorders of thyroid gland
0.000 0.865 0.135
G31.8 Other specified degenerative diseases of nervous system
0.000 0.865 0.135
G47.1 Disorders of excessive somnolence [hypersomnias]
0.000 0.865 0.134
E83.5 Disorders of calcium metabolism
0.000 0.868 0.132
G43 Migraine
0.000 0.870 0.130
G81 Hemiplegia
0.000 0.870 0.130
G46 Vascular syndromes of brain in cerebrovascular diseases
0.000 0.870 0.130
G90-G99 Other disorders of the nervous system
0.000 0.871 0.129
G47.2 Disorders of the sleep-wake schedule
0.000 0.871 0.129
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.000 0.871 0.129
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.872 0.127
E06.9 Thyroiditis, unspecified
0.000 0.874 0.126
K51.0 Ulcerative (chronic) enterocolitis
0.126 0.874 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.000 0.875 0.125
G43.9 Migraine, unspecified
0.000 0.875 0.125
E83.8 Other disorders of mineral metabolism
0.000 0.877 0.123
E83.2 Disorders of zinc metabolism
0.000 0.877 0.123
E83.0 Disorders of copper metabolism
0.000 0.877 0.123
G99.2 Myelopathy in diseases classified elsewhere
0.000 0.877 0.123
G99 Other disorders of nervous system in diseases classified elsewhere
0.000 0.878 0.122
G81.9 Hemiplegia, unspecified
0.000 0.881 0.119
E05.5 Thyroid crisis or storm
0.000 0.881 0.118
E05.4 Thyrotoxicosis factitia
0.000 0.881 0.118
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.881 0.118
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.881 0.118
G40.4 Other generalised epilepsy and epileptic syndromes
0.000 0.882 0.118
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.882 0.118
K51.5 Mucosal proctocolitis
0.116 0.884 0.000
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.885 0.115
K51.8 Other ulcerative colitis
0.114 0.886 0.000
G31.2 Degeneration of nervous system due to alcohol
0.000 0.886 0.114
K51.1 Ulcerative (chronic) ileocolitis
0.113 0.887 0.000
G82 Paraplegia and tetraplegia
0.000 0.887 0.113
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.887 0.112
G41 Status epilepticus
0.000 0.888 0.112
E83.3 Disorders of phosphorus metabolism
0.000 0.889 0.111
E05.8 Other thyrotoxicosis
0.000 0.889 0.110
G04 Encephalitis, myelitis and encephalomyelitis
0.000 0.890 0.110
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.890 0.110
G96 Other disorders of central nervous system
0.000 0.890 0.110
K51.4 Pseudopolyposis of colon
0.108 0.892 0.000
E03 Other hypothyroidism
0.000 0.892 0.108
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.000 0.893 0.107
G40.9 Epilepsy, unspecified
0.000 0.893 0.107
G31.0 Circumscribed brain atrophy
0.000 0.893 0.107
E06.5 Other chronic thyroiditis
0.000 0.894 0.106
G44 Other headache syndromes
0.000 0.895 0.105
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.000 0.896 0.104
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.000 0.897 0.103
G47.4 Narcolepsy and cataplexy
0.000 0.898 0.102
G46.7 Other lacunar syndromes
0.000 0.900 0.100
G40.7 Petit mal, unspecified, without grand mal seizures
0.000 0.900 0.100
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.900 0.100
G96.1 Disorders of meninges, not elsewhere classified
0.000 0.900 0.099
G40.5 Special epileptic syndromes
0.000 0.901 0.099
E06.4 Drug-induced thyroiditis
0.000 0.901 0.098
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.901 0.098
E06.0 Acute thyroiditis
0.000 0.901 0.098
G00 Bacterial meningitis, not elsewhere classified
0.000 0.902 0.098
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.902 0.097
G81.1 Spastic hemiplegia
0.000 0.903 0.097
G98 Other disorders of nervous system, not elsewhere classified
0.000 0.903 0.097
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.903 0.097
E00 Congenital iodine-deficiency syndrome
0.000 0.903 0.097
M35 Other systemic involvement of connective tissue
0.000 0.905 0.095
G40.8 Other epilepsy
0.000 0.905 0.095
G82.1 Spastic paraplegia
0.000 0.906 0.094
G43.2 Status migrainosus
0.000 0.906 0.094
G46.3 Brain stem stroke syndrome
0.000 0.906 0.093
G81.0 Flaccid hemiplegia
0.000 0.907 0.093
G03 Meningitis due to other and unspecified causes
0.000 0.907 0.093
G46.8 Other vascular syndromes of brain in cerebrovascular diseases
0.000 0.907 0.093
G46.6 Pure sensory lacunar syndrome
0.000 0.907 0.093
G46.5 Pure motor lacunar syndrome
0.000 0.907 0.093
G46.2 Posterior cerebral artery syndrome
0.000 0.907 0.093
G46.1 Anterior cerebral artery syndrome
0.000 0.907 0.093
G46.0 Middle cerebral artery syndrome
0.000 0.907 0.093
G70-G73 Diseases of myoneural junction and muscle
0.000 0.907 0.093
G43.0 Migraine without aura [common migraine]
0.000 0.908 0.092
G80 Infantile cerebral palsy
0.000 0.908 0.092
G46.4 Cerebellar stroke syndrome
0.000 0.908 0.092
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.908 0.091
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.000 0.908 0.091
G06.1 Intraspinal abscess and granuloma
0.000 0.909 0.091
G45 Transient cerebral ischaemic attacks and related syndromes
0.000 0.910 0.090
G06.2 Extradural and subdural abscess, unspecified
0.000 0.910 0.090
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.000 0.911 0.089
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.911 0.089
M35.7 Hypermobility syndrome
0.000 0.911 0.089
E07 Other disorders of thyroid
0.000 0.911 0.088
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.000 0.912 0.088
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.000 0.912 0.088
G82.5 Tetraplegia, unspecified
0.000 0.913 0.087
K50-K52 Noninfective enteritis and colitis
0.086 0.914 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.914 0.086
G94 Other disorders of brain in diseases classified elsewhere
0.000 0.915 0.085
G82.4 Spastic tetraplegia
0.000 0.915 0.085
E06.1 Subacute thyroiditis
0.000 0.915 0.085
E03.9 Hypothyroidism, unspecified
0.000 0.915 0.085
G45.3 Amaurosis fugax
0.000 0.916 0.084
K50.9 Crohn's disease, unspecified
0.084 0.916 0.000
K50 Crohn's disease [regional enteritis]
0.084 0.916 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.000 0.917 0.083
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.000 0.917 0.083
G44.3 Chronic posttraumatic headache
0.000 0.918 0.082
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.918 0.082
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.000 0.919 0.081
G82.3 Flaccid tetraplegia
0.000 0.919 0.081
G82.0 Flaccid paraplegia
0.000 0.919 0.081
G41.8 Other status epilepticus
0.000 0.920 0.080
G41.2 Complex partial status epilepticus
0.000 0.920 0.080
G41.1 Petit mal status epilepticus
0.000 0.920 0.080
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.000 0.920 0.080
G44.2 Tension-type headache
0.000 0.920 0.080
G96.0 Cerebrospinal fluid leak
0.000 0.921 0.079
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.000 0.921 0.079
G04.1 Tropical spastic paraplegia
0.000 0.921 0.079
G04.0 Acute disseminated encephalitis
0.000 0.921 0.079
G41.0 Grand mal status epilepticus
0.000 0.921 0.079
G96.9 Disorder of central nervous system, unspecified
0.000 0.921 0.079
G95 Other diseases of spinal cord
0.000 0.922 0.078
G43.3 Complicated migraine
0.000 0.922 0.078
G47.8 Other sleep disorders
0.000 0.922 0.078
E03.5 Myxoedema coma
0.000 0.922 0.078
E03.4 Atrophy of thyroid (acquired)
0.000 0.922 0.078
E03.3 Postinfectious hypothyroidism
0.000 0.922 0.078
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.000 0.923 0.077
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.000 0.923 0.077
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.000 0.923 0.077
G30 Alzheimer's disease
0.000 0.923 0.077
K50.8 Other Crohn's disease
0.076 0.924 0.000
E03.8 Other specified hypothyroidism
0.000 0.925 0.075
G92 Toxic encephalopathy
0.000 0.925 0.074
G00.1 Pneumococcal meningitis
0.000 0.926 0.074
G91 Hydrocephalus
0.000 0.926 0.074
G80.8 Other infantile cerebral palsy
0.000 0.926 0.073
G44.8 Other specified headache syndromes
0.000 0.927 0.073
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.927 0.073
G97.1 Other reaction to spinal and lumbar puncture
0.000 0.928 0.072
G70 Myasthenia gravis and other myoneural disorders
0.000 0.928 0.072
E03.1 Congenital hypothyroidism without goitre
0.000 0.929 0.071
G96.8 Other specified disorders of central nervous system
0.000 0.929 0.071
G00.8 Other bacterial meningitis
0.000 0.929 0.070
G00.3 Staphylococcal meningitis
0.000 0.929 0.070
G00.2 Streptococcal meningitis
0.000 0.929 0.070
G00.0 Haemophilus meningitis
0.000 0.929 0.070
E07.8 Other specified disorders of thyroid
0.000 0.930 0.070
G90 Disorders of autonomic nervous system
0.000 0.930 0.070
G83 Other paralytic syndromes
0.000 0.930 0.070
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.930 0.069
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.930 0.069
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.930 0.069
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.930 0.069
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.930 0.069
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.930 0.069
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.930 0.069
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.930 0.069
G41.9 Status epilepticus, unspecified
0.000 0.930 0.069
G44.0 Cluster headache syndrome
0.000 0.931 0.069
G95.1 Vascular myelopathies
0.000 0.931 0.069
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.931 0.068
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.931 0.068
M35.5 Multifocal fibrosclerosis
0.000 0.931 0.068
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.931 0.068
K51.3 Ulcerative (chronic) rectosigmoiditis
0.068 0.932 0.000
G43.1 Migraine with aura [classical migraine]
0.000 0.932 0.068
M35.8 Other specified systemic involvement of connective tissue
0.000 0.933 0.067
G93 Other disorders of brain
0.000 0.933 0.067
G03.8 Meningitis due to other specified causes
0.000 0.933 0.067
G03.2 Benign recurrent meningitis [Mollaret]
0.000 0.933 0.067
G03.1 Chronic meningitis
0.000 0.933 0.067
G03.0 Nonpyogenic meningitis
0.000 0.933 0.067
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.933 0.067
G80.9 Infantile cerebral palsy, unspecified
0.000 0.933 0.067
M35.1 Other overlap syndromes
0.000 0.934 0.066
G80.4 Ataxic cerebral palsy
0.000 0.934 0.066
G80.3 Dyskinetic cerebral palsy
0.000 0.934 0.066
G97.9 Postprocedural disorder of nervous system, unspecified
0.000 0.934 0.066
G97.2 Intracranial hypotension following ventricular shunting
0.000 0.934 0.066
G44.1 Vascular headache, not elsewhere classified
0.000 0.934 0.065
G80.1 Spastic diplegia
0.000 0.935 0.065
G45.2 Multiple and bilateral precerebral artery syndromes
0.000 0.935 0.065
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.000 0.936 0.064
G02.1 Meningitis in mycoses
0.000 0.936 0.064
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.936 0.064
G95.8 Other specified diseases of spinal cord
0.000 0.936 0.064
E07.1 Dyshormogenetic goitre
0.000 0.936 0.064
E07.0 Hypersecretion of calcitonin
0.000 0.936 0.064
M35.2 Behcet's disease
0.000 0.937 0.063
G97.8 Other postprocedural disorders of nervous system
0.000 0.937 0.063
G43.8 Other migraine
0.000 0.938 0.062
G45.1 Carotid artery syndrome (hemispheric)
0.000 0.938 0.062
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.000 0.938 0.061
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.000 0.938 0.061
G94.2 Hydrocephalus in other diseases classified elsewhere
0.000 0.939 0.061
G91.0 Communicating hydrocephalus
0.000 0.939 0.060
G82.2 Paraplegia, unspecified
0.000 0.940 0.060
G93.8 Other specified disorders of brain
0.000 0.940 0.060
G44.4 Drug-induced headache, not elsewhere classified
0.000 0.941 0.059
G91.2 Normal-pressure hydrocephalus
0.000 0.941 0.059
G97.0 Cerebrospinal fluid leak from spinal puncture
0.000 0.941 0.059
G30.0 Alzheimer's disease with early onset
0.000 0.941 0.059
G00.9 Bacterial meningitis, unspecified
0.000 0.941 0.058
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.000 0.941 0.058
G80.0 Spastic cerebral palsy
0.000 0.942 0.058
G95.0 Syringomyelia and syringobulbia
0.000 0.943 0.057
G83.2 Monoplegia of upper limb
0.000 0.943 0.057
G93.4 Encephalopathy, unspecified
0.000 0.944 0.056
G03.9 Meningitis, unspecified
0.000 0.944 0.056
G93.0 Cerebral cysts
0.000 0.944 0.056
G70.0 Myasthenia gravis
0.000 0.945 0.055
G94.1 Hydrocephalus in neoplastic disease
0.000 0.945 0.055
G90.9 Disorder of autonomic nervous system, unspecified
0.000 0.945 0.055
G70.9 Myoneural disorder, unspecified
0.000 0.945 0.055
G20-G26 Extrapyramidal and movement disorders
0.000 0.946 0.054
G91.3 Posttraumatic hydrocephalus, unspecified
0.000 0.946 0.053
G45.4 Transient global amnesia
0.000 0.947 0.053
G83.1 Monoplegia of lower limb
0.000 0.948 0.052
N76 Other inflammation of vagina and vulva
0.000 0.948 0.052
G70.8 Other specified myoneural disorders
0.000 0.948 0.052
G70.2 Congenital and developmental myasthenia
0.000 0.948 0.052
G70.1 Toxic myoneural disorders
0.000 0.948 0.052
G93.1 Anoxic brain damage, not elsewhere classified
0.000 0.948 0.052
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.948 0.052
G80.2 Infantile hemiplegia
0.000 0.948 0.051
N76.8 Other specified inflammation of vagina and vulva
0.000 0.949 0.051
N76.4 Abscess of vulva
0.000 0.949 0.051
G90.8 Other disorders of autonomic nervous system
0.000 0.949 0.050
G90.4 Autonomic dysreflexia
0.000 0.950 0.050
G90.1 Familial dysautonomia [Riley-Day]
0.000 0.950 0.050
K50.1 Crohn's disease of large intestine
0.050 0.950 0.000
G71 Primary disorders of muscles
0.000 0.950 0.050
G83.5 Locked-in syndrome
0.000 0.950 0.050
G83.0 Diplegia of upper limbs
0.000 0.950 0.050
G91.8 Other hydrocephalus
0.000 0.950 0.050
G93.5 Compression of brain
0.000 0.950 0.050
N76.0 Acute vaginitis
0.000 0.951 0.049
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.951 0.049
G02.0 Meningitis in viral diseases classified elsewhere
0.000 0.951 0.049
G83.8 Other specified paralytic syndromes
0.000 0.951 0.049
G45.0 Vertebro-basilar artery syndrome
0.000 0.951 0.049
G30.9 Alzheimer's disease, unspecified
0.000 0.951 0.049
G93.7 Reye's syndrome
0.000 0.951 0.048
G73.7 Myopathy other diseases classified elsewhere
0.000 0.952 0.048
G73.6 Myopathy in metabolic diseases
0.000 0.952 0.048
G73.5 Myopathy in endocrine diseases
0.000 0.952 0.048
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.000 0.952 0.048
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.000 0.952 0.048
G73.2 Other myasthenic syndromes in neoplastic disease
0.000 0.952 0.048
G73.1 Eaton-Lambert syndrome
0.000 0.952 0.048
G73.0 Myasthenic syndromes in endocrine diseases
0.000 0.952 0.048
G06.0 Intracranial abscess and granuloma
0.001 0.953 0.046
G83.3 Monoplegia, unspecified
0.000 0.953 0.047
G90.3 Multisystem degeneration
0.000 0.953 0.047
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.000 0.954 0.046
G90.2 Horner's syndrome
0.000 0.955 0.045
N76.3 Subacute and chronic vulvitis
0.000 0.956 0.044
I69 Sequelae of cerebrovascular disease
0.000 0.956 0.044
G10 Huntington's disease
0.000 0.956 0.043
E07.9 Disorder of thyroid, unspecified
0.000 0.956 0.044
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.004 0.956 0.040
G14 Postpolio syndrome
0.000 0.956 0.043
G72 Other myopathies
0.000 0.957 0.043
G91.1 Obstructive hydrocephalus
0.000 0.957 0.043
G30.8 Other Alzheimer's disease
0.000 0.958 0.042
N76.5 Ulceration of vagina
0.000 0.958 0.042
G30.1 Alzheimer's disease with late onset
0.000 0.959 0.040
N76.2 Acute vulvitis
0.000 0.960 0.040
G23 Other degenerative diseases of basal ganglia
0.000 0.960 0.040
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.960 0.040
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.960 0.040
N76.1 Subacute and chronic vaginitis
0.000 0.961 0.039
G95.9 Disease of spinal cord, unspecified
0.000 0.961 0.039
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.000 0.961 0.039
G22 Parkinsonism in diseases classified elsewhere
0.000 0.961 0.039
Z37.0 Single live birth
0.038 0.962 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.963 0.037
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.963 0.036
G71.9 Primary disorder of muscle, unspecified
0.000 0.964 0.036
G71.8 Other primary disorders of muscles
0.000 0.964 0.036
G71.2 Congenital myopathies
0.000 0.964 0.036
G21 Secondary Parkinsonism
0.000 0.964 0.036
G93.3 Postviral fatigue syndrome
0.000 0.965 0.035
G71.1 Myotonic disorders
0.000 0.965 0.035
I69.3 Sequelae of cerebral infarction
0.000 0.965 0.035
G25 Other extrapyramidal and movement disorders
0.000 0.965 0.035
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.034 0.966 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.001 0.966 0.033
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.000 0.966 0.033
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.000 0.966 0.033
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.000 0.966 0.033
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.000 0.966 0.033
G90.0 Idiopathic peripheral autonomic neuropathy
0.000 0.967 0.033
G83.9 Paralytic syndrome, unspecified
0.000 0.967 0.033
N76.6 Ulceration of vulva
0.000 0.967 0.032
Z37 Outcome of delivery
0.032 0.968 0.000
G72.1 Alcoholic myopathy
0.000 0.968 0.032
G83.4 Cauda equina syndrome
0.000 0.968 0.032
G12 Spinal muscular atrophy and related syndromes
0.001 0.968 0.031
G64 Other disorders of peripheral nervous system
0.003 0.968 0.029
G72.3 Periodic paralysis
0.000 0.969 0.031
G72.2 Myopathy due to other toxic agents
0.000 0.969 0.031
Z37.2 Twins, both liveborn
0.031 0.969 0.000
G72.8 Other specified myopathies
0.000 0.970 0.030
G23.8 Other specified degenerative diseases of basal ganglia
0.000 0.970 0.030
G72.4 Inflammatory myopathy, not elsewhere classified
0.000 0.970 0.029
G11 Hereditary ataxia
0.001 0.970 0.029
E83.4 Disorders of magnesium metabolism
0.000 0.971 0.029
G62 Other polyneuropathies
0.001 0.971 0.028
G23.9 Degenerative disease of basal ganglia, unspecified
0.000 0.971 0.029
G23.3 Multiple system atrophy, cerebellar type
0.000 0.971 0.029
G23.2 Striatonigral degeneration
0.000 0.971 0.029
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.000 0.971 0.029
G23.0 Hallervorden-Spatz disease
0.000 0.971 0.029
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.971 0.028
G93.6 Cerebral oedema
0.000 0.972 0.028
G72.0 Drug-induced myopathy
0.000 0.972 0.028
G91.9 Hydrocephalus, unspecified
0.000 0.972 0.028
M35.3 Polymyalgia rheumatica
0.000 0.972 0.028
G21.1 Other drug-induced secondary Parkinsonism
0.000 0.973 0.027
G25.3 Myoclonus
0.000 0.973 0.027
K50.0 Crohn's disease of small intestine
0.027 0.973 0.000
G25.0 Essential tremor
0.000 0.974 0.026
G60 Hereditary and idiopathic neuropathy
0.004 0.974 0.022
G21.8 Other secondary Parkinsonism
0.000 0.974 0.026
G21.4 Vascular parkinsonism
0.000 0.974 0.026
G21.3 Postencephalitic Parkinsonism
0.000 0.974 0.026
G21.2 Secondary Parkinsonism due to other external agents
0.000 0.974 0.026
G21.0 Malignant neuroleptic syndrome
0.000 0.974 0.026
G25.2 Other specified forms of tremor
0.000 0.974 0.026
Z37.1 Single stillbirth
0.026 0.974 0.000
G25.9 Extrapyramidal and movement disorder, unspecified
0.000 0.974 0.026
G24 Dystonia
0.000 0.974 0.026
G25.5 Other chorea
0.000 0.975 0.025
G25.6 Drug-induced tics and other tics of organic origin
0.000 0.975 0.025
G25.4 Drug-induced chorea
0.000 0.975 0.025
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.975 0.025
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.976 0.024
G62.1 Alcoholic polyneuropathy
0.001 0.976 0.023
G62.9 Polyneuropathy, unspecified
0.000 0.976 0.024
I65.2 Occlusion and stenosis of carotid artery
0.000 0.976 0.024
Z37.3 Twins, one liveborn and one stillborn
0.023 0.977 0.000
G93.2 Benign intracranial hypertension
0.000 0.977 0.023
Z37.9 Outcome of delivery unspecified
0.023 0.977 0.000
Z37.7 Other multiple births, all stillborn
0.023 0.977 0.000
Z37.6 Other multiple births, some liveborn
0.023 0.977 0.000
Z37.4 Twins, both stillborn
0.023 0.977 0.000
G25.1 Drug-induced tremor
0.000 0.977 0.023
G12.9 Spinal muscular atrophy, unspecified
0.001 0.977 0.022
G12.8 Other spinal muscular atrophies and related syndromes
0.001 0.977 0.022
G12.1 Other inherited spinal muscular atrophy
0.001 0.977 0.022
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.001 0.977 0.022
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.977 0.023
Z37.5 Other multiple births, all liveborn
0.023 0.977 0.000
I71 Aortic aneurysm and dissection
0.000 0.978 0.022
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.978 0.022
G11.8 Other hereditary ataxias
0.001 0.978 0.021
G11.3 Cerebellar ataxia with defective DNA repair
0.001 0.978 0.021
G11.2 Late-onset cerebellar ataxia
0.001 0.978 0.021
G11.0 Congenital nonprogressive ataxia
0.001 0.978 0.021
G63 Polyneuropathy in diseases classified elsewhere
0.004 0.978 0.018
G71.0 Muscular dystrophy
0.000 0.978 0.021
G62.2 Polyneuropathy due to other toxic agents
0.001 0.979 0.020
G93.9 Disorder of brain, unspecified
0.000 0.979 0.021
G21.9 Secondary Parkinsonism, unspecified
0.000 0.979 0.020
G11.1 Early-onset cerebellar ataxia
0.001 0.980 0.020
I60-I69 Cerebrovascular diseases
0.000 0.980 0.020
G60.8 Other hereditary and idiopathic neuropathies
0.002 0.980 0.018
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.980 0.020
K90-K93 Other diseases of the digestive system
0.000 0.980 0.020
G11.4 Hereditary spastic paraplegia
0.001 0.981 0.019
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.003 0.981 0.017
G60.3 Idiopathic progressive neuropathy
0.003 0.981 0.016
G60.2 Neuropathy in association with hereditary ataxia
0.003 0.981 0.016
G60.1 Refsum's disease
0.003 0.981 0.016
G24.3 Spasmodic torticollis
0.000 0.981 0.019
G72.9 Myopathy, unspecified
0.000 0.981 0.018
G24.4 Idiopathic orofacial dystonia
0.000 0.981 0.018
G24.2 Idiopathic nonfamilial dystonia
0.000 0.981 0.018
G24.1 Idiopathic familial dystonia
0.000 0.981 0.018
G24.0 Drug-induced dystonia
0.000 0.981 0.018
G20 Parkinson's disease
0.000 0.981 0.019
E04 Other non-toxic goitre
0.000 0.982 0.018
G45.9 Transient cerebral ischaemic attack, unspecified
0.000 0.982 0.018
I73.9 Peripheral vascular disease, unspecified
0.000 0.982 0.018
G62.0 Drug-induced polyneuropathy
0.001 0.982 0.017
G24.9 Dystonia, unspecified
0.000 0.982 0.018
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.982 0.018
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.983 0.017
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.983 0.017
G24.8 Other dystonia
0.000 0.983 0.017
S06.3 Focal brain injury
0.000 0.983 0.017
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.983 0.017
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.983 0.017
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.983 0.017
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.983 0.016
I73 Other peripheral vascular diseases
0.000 0.983 0.016
G25.8 Other specified extrapyramidal and movement disorders
0.000 0.984 0.016
I63 Cerebral infarction
0.000 0.984 0.016
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.984 0.016
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.984 0.016
I77 Other disorders of arteries and arterioles
0.000 0.984 0.016
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.984 0.016
I71.0 Dissection of aorta [any part]
0.000 0.984 0.016
G63.8 Polyneuropathy in other diseases classified elsewhere
0.003 0.984 0.013
G63.6 Polyneuropathy in other musculoskeletal disorders
0.003 0.984 0.013
G63.5 Polyneuropathy in systemic connective tissue disorders
0.003 0.984 0.013
G63.4 Polyneuropathy in nutritional deficiency
0.003 0.984 0.013
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.003 0.984 0.013
G63.1 Polyneuropathy in neoplastic disease
0.003 0.984 0.013
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.003 0.984 0.013
I65.1 Occlusion and stenosis of basilar artery
0.000 0.984 0.016
I77.2 Rupture of artery
0.000 0.985 0.015
G61 Inflammatory polyneuropathy
0.004 0.985 0.010
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.985 0.014
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.986 0.014
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.986 0.014
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.986 0.014
Z41 Procedures for purposes other than remedying health state
0.014 0.986 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.986 0.014
I84.9 Unspecified haemorrhoids without complication
0.014 0.986 0.000
H53.2 Diplopia
0.000 0.986 0.014
I74 Arterial embolism and thrombosis
0.000 0.986 0.014
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.986 0.014
E04.8 Other specified non-toxic goitre
0.000 0.986 0.013
I77.8 Other specified disorders of arteries and arterioles
0.000 0.986 0.013
E70-E90 Metabolic disorders
0.000 0.987 0.013
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.987 0.013
E04.0 Non-toxic diffuse goitre
0.000 0.987 0.013
I72 Other aneurysm
0.000 0.987 0.013
I77.1 Stricture of artery
0.000 0.987 0.013
I61 Intracerebral haemorrhage
0.000 0.987 0.013
I62 Other nontraumatic intracranial haemorrhage
0.000 0.987 0.013
I74.8 Embolism and thrombosis of other arteries
0.000 0.987 0.013
G11.9 Hereditary ataxia, unspecified
0.001 0.987 0.012
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.987 0.012
S06.31 Focal brain injury (with open intracranial wound)
0.000 0.987 0.012
I70 Atherosclerosis
0.000 0.988 0.012
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.988 0.012
E89.0 Postprocedural hypothyroidism
0.000 0.988 0.012
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.988 0.012
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.988 0.012
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.988 0.012
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.988 0.012
I77.5 Necrosis of artery
0.000 0.988 0.012
I77.4 Coeliac artery compression syndrome
0.000 0.988 0.012
I77.3 Arterial fibromuscular dysplasia
0.000 0.988 0.012
Z41.8 Other procedures for purposes other than remedying health state
0.012 0.988 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.988 0.012
I72.4 Aneurysm of artery of lower extremity
0.000 0.988 0.012
C32.0 Glottis
0.011 0.989 0.000
R03.1 Nonspecific low blood-pressure reading
0.000 0.989 0.011

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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