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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2394423
log Bayes Factor = 62.0314
Chromosome 6   position 31,032,042  (GRCh37) Explore rs2394423 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
R31 Unspecified haematuria
0.931 0.069 0.000
L40.9 Psoriasis, unspecified
0.000 0.160 0.840
L40 Psoriasis
0.000 0.231 0.769
L40.0 Psoriasis vulgaris
0.000 0.287 0.713
L40.5 Arthropathic psoriasis
0.000 0.295 0.705
G93 Other disorders of brain
0.684 0.316 0.000
G90-G99 Other disorders of the nervous system
0.681 0.319 0.000
G91 Hydrocephalus
0.678 0.322 0.000
G93.2 Benign intracranial hypertension
0.667 0.333 0.000
G91.9 Hydrocephalus, unspecified
0.664 0.336 0.000
K90 Intestinal malabsorption
0.000 0.348 0.652
G93.0 Cerebral cysts
0.649 0.351 0.000
G93.8 Other specified disorders of brain
0.640 0.360 0.000
G90 Disorders of autonomic nervous system
0.624 0.376 0.000
G91.1 Obstructive hydrocephalus
0.619 0.381 0.000
G35 Multiple sclerosis
0.000 0.399 0.601
G94 Other disorders of brain in diseases classified elsewhere
0.595 0.405 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.437 0.563
G90.3 Multisystem degeneration
0.563 0.437 0.000
G93.6 Cerebral oedema
0.551 0.449 0.000
L40.4 Guttate psoriasis
0.000 0.449 0.551
L40.3 Pustulosis palmaris et plantaris
0.000 0.449 0.551
L40.2 Acrodermatitis continua
0.000 0.449 0.551
L40.1 Generalised pustular psoriasis
0.000 0.449 0.551
G93.5 Compression of brain
0.541 0.459 0.000
G95 Other diseases of spinal cord
0.538 0.462 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.537 0.463 0.000
G91.8 Other hydrocephalus
0.522 0.478 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.519 0.481 0.000
G91.2 Normal-pressure hydrocephalus
0.519 0.481 0.000
L40.8 Other psoriasis
0.000 0.483 0.517
G90.9 Disorder of autonomic nervous system, unspecified
0.509 0.491 0.000
K90.8 Other intestinal malabsorption
0.000 0.498 0.501
G94.2 Hydrocephalus in other diseases classified elsewhere
0.496 0.504 0.000
G94.1 Hydrocephalus in neoplastic disease
0.491 0.509 0.000
G93.7 Reye's syndrome
0.490 0.510 0.000
G92 Toxic encephalopathy
0.488 0.512 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.486 0.514 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.483 0.517 0.000
G95.9 Disease of spinal cord, unspecified
0.481 0.519 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.532 0.468
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.532 0.468
K90.1 Tropical sprue
0.000 0.532 0.468
G90.0 Idiopathic peripheral autonomic neuropathy
0.467 0.533 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.539 0.461
G91.0 Communicating hydrocephalus
0.460 0.540 0.000
G90.8 Other disorders of autonomic nervous system
0.448 0.552 0.000
G90.4 Autonomic dysreflexia
0.448 0.552 0.000
G90.1 Familial dysautonomia [Riley-Day]
0.448 0.552 0.000
G93.3 Postviral fatigue syndrome
0.439 0.561 0.000
G95.0 Syringomyelia and syringobulbia
0.435 0.565 0.000
G97.8 Other postprocedural disorders of nervous system
0.427 0.572 0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere
0.427 0.573 0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere
0.427 0.573 0.000
G90.2 Horner's syndrome
0.424 0.576 0.000
G96 Other disorders of central nervous system
0.405 0.594 0.000
G95.8 Other specified diseases of spinal cord
0.400 0.600 0.000
E03 Other hypothyroidism
0.392 0.604 0.004
G97.0 Cerebrospinal fluid leak from spinal puncture
0.390 0.610 0.000
G97.9 Postprocedural disorder of nervous system, unspecified
0.372 0.627 0.000
G97.2 Intracranial hypotension following ventricular shunting
0.372 0.627 0.000
G93.9 Disorder of brain, unspecified
0.357 0.642 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.340 0.660 0.000
G95.1 Vascular myelopathies
0.317 0.683 0.000
G96.8 Other specified disorders of central nervous system
0.312 0.688 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.310 0.690 0.000
G96.9 Disorder of central nervous system, unspecified
0.291 0.709 0.000
G96.0 Cerebrospinal fluid leak
0.287 0.713 0.000
E03.5 Myxoedema coma
0.281 0.716 0.003
E03.4 Atrophy of thyroid (acquired)
0.281 0.716 0.003
E03.3 Postinfectious hypothyroidism
0.281 0.716 0.003
E03.1 Congenital hypothyroidism without goitre
0.281 0.716 0.003
E03.0 Congenital hypothyroidism with diffuse goitre
0.281 0.716 0.003
D86.9 Sarcoidosis, unspecified
0.000 0.727 0.273
G93.4 Encephalopathy, unspecified
0.267 0.732 0.000
M45 Ankylosing spondylitis
0.267 0.733 0.000
D86 Sarcoidosis
0.000 0.735 0.265
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.262 0.735 0.003
E03.8 Other specified hypothyroidism
0.251 0.746 0.003
G35-G37 Demyelinating diseases of the central nervous system
0.001 0.749 0.250
M51.2 Other specified intervertebral disk displacement
0.000 0.749 0.251
D86.8 Sarcoidosis of other and combined sites
0.000 0.752 0.248
D86.0 Sarcoidosis of lung
0.000 0.762 0.238
D86.1 Sarcoidosis of lymph nodes
0.000 0.767 0.233
G95.2 Cord compression, unspecified
0.226 0.774 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.224 0.776 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.222 0.778 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.218 0.782 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.215 0.785 0.000
D86.3 Sarcoidosis of skin
0.000 0.802 0.198
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.192 0.808 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.192 0.808 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.192 0.808 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.192 0.808 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.192 0.808 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.192 0.808 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.809 0.190
G37 Other demyelinating diseases of central nervous system
0.001 0.812 0.187
L40-L45 Papulosquamous disorders
0.000 0.817 0.183
G96.1 Disorders of meninges, not elsewhere classified
0.170 0.829 0.001
G36 Other acute disseminated demyelination
0.001 0.830 0.168
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.156 0.843 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.156 0.843 0.000
E83.1 Disorders of iron metabolism
0.000 0.853 0.147
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.858 0.142
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.859 0.140
K51.9 Ulcerative colitis, unspecified
0.136 0.864 0.000
G37.5 Concentric sclerosis [Balo]
0.001 0.865 0.134
G37.4 Subacute necrotising myelitis
0.001 0.865 0.134
G37.2 Central pontine myelinolysis
0.001 0.865 0.134
G37.1 Central demyelination of corpus callosum
0.001 0.865 0.134
G37.0 Diffuse sclerosis
0.001 0.865 0.134
L44 Other papulosquamous disorders
0.000 0.869 0.131
L41 Parapsoriasis
0.000 0.869 0.131
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.869 0.131
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.871 0.129
K51.4 Pseudopolyposis of colon
0.127 0.873 0.000
L42 Pityriasis rosea
0.000 0.873 0.126
K51 Ulcerative colitis
0.126 0.874 0.000
G36.9 Acute disseminated demyelination, unspecified
0.001 0.878 0.121
G36.8 Other specified acute disseminated demyelination
0.001 0.878 0.121
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.001 0.878 0.121
K51.8 Other ulcerative colitis
0.112 0.888 0.000
G36.0 Neuromyelitis optica [Devic]
0.001 0.889 0.110
M51 Other intervertebral disk disorders
0.000 0.891 0.109
E00-E07 Disorders of thyroid gland
0.097 0.894 0.009
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.097 0.902 0.000
K51.2 Ulcerative (chronic) proctitis
0.097 0.903 0.000
E07 Other disorders of thyroid
0.091 0.904 0.005
L41.9 Parapsoriasis, unspecified
0.000 0.906 0.094
L41.8 Other parapsoriasis
0.000 0.906 0.094
L41.5 Retiform parapsoriasis
0.000 0.906 0.094
L41.4 Large plaque parapsoriasis
0.000 0.906 0.094
L41.3 Small plaque parapsoriasis
0.000 0.906 0.094
L41.2 Lymphomatoid papulosis
0.000 0.906 0.094
L41.1 Pityriasis lichenoides chronica
0.000 0.906 0.094
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.906 0.094
L44.9 Papulosquamous disorder, unspecified
0.000 0.906 0.094
L44.8 Other specified papulosquamous disorders
0.000 0.906 0.094
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.906 0.094
L44.3 Lichen ruber moniliformis
0.000 0.906 0.094
L44.2 Lichen striatus
0.000 0.906 0.094
L44.1 Lichen nitidus
0.000 0.906 0.094
L44.0 Pityriasis rubra pilaris
0.000 0.906 0.094
K51.1 Ulcerative (chronic) ileocolitis
0.091 0.909 0.000
E07.9 Disorder of thyroid, unspecified
0.090 0.910 0.000
K51.5 Mucosal proctocolitis
0.090 0.910 0.000
M51.8 Other specified intervertebral disk disorders
0.000 0.910 0.090
M51.4 Schmorl's nodes
0.000 0.913 0.087
D80-D89 Certain disorders involving the immune mechanism
0.000 0.921 0.079
M51.3 Other specified intervertebral disk degeneration
0.000 0.921 0.078
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.000 0.921 0.078
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.070 0.924 0.006
E00 Congenital iodine-deficiency syndrome
0.070 0.924 0.006
E02 Subclinical iodine-deficiency hypothyroidism
0.070 0.924 0.006
L43 Lichen planus
0.000 0.926 0.073
E07.1 Dyshormogenetic goitre
0.065 0.931 0.004
E07.0 Hypersecretion of calcitonin
0.065 0.931 0.004
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.000 0.933 0.067
K51.0 Ulcerative (chronic) enterocolitis
0.066 0.933 0.000
E06 Thyroiditis
0.061 0.934 0.005
M51.9 Intervertebral disk disorder, unspecified
0.000 0.939 0.060
D81 Combined immunodeficiencies
0.000 0.943 0.057
D82 Immunodeficiency associated with other major defects
0.000 0.943 0.057
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified
0.000 0.943 0.056
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region
0.000 0.943 0.056
M51.37 Other intervertebral disc degeneration, lumbosacral region
0.000 0.943 0.056
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.945 0.055
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.050 0.945 0.005
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.050 0.945 0.005
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.050 0.945 0.005
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.050 0.945 0.005
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.050 0.945 0.005
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.050 0.945 0.005
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.050 0.945 0.005
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.050 0.945 0.005
D83 Common variable immunodeficiency
0.000 0.945 0.055
L43.3 Subacute (active) lichen planus
0.000 0.947 0.053
L43.2 Lichenoid drug reaction
0.000 0.947 0.053
L43.1 Bullous lichen planus
0.000 0.947 0.053
L43.0 Hypertrophic lichen planus
0.000 0.947 0.053
K51.3 Ulcerative (chronic) rectosigmoiditis
0.052 0.948 0.000
E06.5 Other chronic thyroiditis
0.049 0.948 0.003
D80 Immunodeficiency with predominantly antibody defects
0.000 0.949 0.051
E07.8 Other specified disorders of thyroid
0.047 0.949 0.004
E06.1 Subacute thyroiditis
0.046 0.950 0.003
M45-M49 Spondylopathies
0.049 0.951 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.952 0.048
G99.2 Myelopathy in diseases classified elsewhere
0.048 0.952 0.000
E06.4 Drug-induced thyroiditis
0.044 0.952 0.004
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.044 0.952 0.004
E06.0 Acute thyroiditis
0.044 0.952 0.004
L43.8 Other lichen planus
0.000 0.953 0.046
M46 Other inflammatory spondylopathies
0.045 0.955 0.000
K90-K93 Other diseases of the digestive system
0.000 0.955 0.045
E10.3 With ophthalmic complications
0.000 0.956 0.044
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.958 0.042
M46.9 Inflammatory spondylopathy, unspecified
0.041 0.959 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.959 0.041
D84 Other immunodeficiencies
0.001 0.959 0.040
D81.9 Combined immunodeficiency, unspecified
0.000 0.959 0.041
D81.8 Other combined immunodeficiencies
0.000 0.959 0.041
D81.7 Major histocompatibility complex class II deficiency
0.000 0.959 0.041
D81.6 Major histocompatibility complex class I deficiency
0.000 0.959 0.041
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.959 0.041
D81.4 Nezelof's syndrome
0.000 0.959 0.041
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.959 0.041
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.959 0.041
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.959 0.041
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.959 0.041
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.959 0.041
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.959 0.041
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.959 0.041
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.959 0.041
D82.2 Immunodeficiency with short-limbed stature
0.000 0.959 0.041
D82.0 Wiskott-Aldrich syndrome
0.000 0.959 0.041
D89.1 Cryoglobulinaemia
0.000 0.959 0.041
D82.1 Di George's syndrome
0.000 0.959 0.041
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.040 0.960 0.000
E06.3 Autoimmune thyroiditis
0.038 0.960 0.003
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.960 0.040
D89.3 Immune reconstitution syndrome
0.000 0.960 0.040
C90.0 Multiple myeloma
0.000 0.960 0.040
D83.8 Other common variable immunodeficiencies
0.000 0.960 0.039
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.960 0.039
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.960 0.039
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.960 0.039
E16 Other disorders of pancreatic internal secretion
0.000 0.961 0.039
E10.1 With ketoacidosis
0.000 0.962 0.038
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.962 0.038
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.038 0.962 0.000
D83.9 Common variable immunodeficiency, unspecified
0.000 0.963 0.037
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.963 0.037
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.963 0.036
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.963 0.036
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.963 0.036
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.963 0.036
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.963 0.036
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.963 0.036
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.963 0.036
E04 Other non-toxic goitre
0.035 0.964 0.001
E06.9 Thyroiditis, unspecified
0.032 0.964 0.004
M06.9 Rheumatoid arthritis, unspecified
0.036 0.964 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.964 0.036
M46.2 Osteomyelitis of vertebra
0.035 0.965 0.000
E10.2 With renal complications
0.000 0.965 0.035
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.965 0.034
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.966 0.034
M06 Other rheumatoid arthritis
0.034 0.966 0.000
M46.4 Discitis, unspecified
0.033 0.967 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.033 0.967 0.000
E10.0 With coma
0.000 0.967 0.033
M06.0 Seronegative rheumatoid arthritis
0.032 0.968 0.000
M46.8 Other specified inflammatory spondylopathies
0.032 0.968 0.000
M46.5 Other infective spondylopathies
0.032 0.968 0.000
M46.0 Spinal enthesopathy
0.032 0.968 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.968 0.032
R04.0 Epistaxis
0.032 0.968 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.968 0.032
M46.3 Infection of intervertebral disk (pyogenic)
0.031 0.969 0.000
E10.6 With other specified complications
0.000 0.969 0.031
M06.3 Rheumatoid nodule
0.031 0.969 0.000
M49 Spondylopathies in diseases classified elsewhere
0.030 0.969 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.030 0.969 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.030 0.970 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.030 0.970 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.030 0.970 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.030 0.970 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.030 0.970 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.030 0.970 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.030 0.970 0.000
E10.7 With multiple complications
0.000 0.970 0.030
D84.8 Other specified immunodeficiencies
0.001 0.970 0.029
D84.1 Defects in the complement system
0.001 0.970 0.029
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.001 0.970 0.029
E10.8 With unspecified complications
0.000 0.970 0.029
M46.1 Sacro-iliitis, not elsewhere classified
0.029 0.971 0.000
E10.5 With peripheral circulatory complications
0.000 0.971 0.029
M06.34 Rheumatoid nodule (Hand)
0.029 0.971 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.029 0.971 0.000
E83 Disorders of mineral metabolism
0.000 0.971 0.029
E16.1 Other hypoglycaemia
0.000 0.971 0.028
M06.1 Adult-onset Still's disease
0.028 0.972 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.028 0.972 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.972 0.028
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.972 0.028
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.972 0.028
E16.4 Abnormal secretion of gastrin
0.000 0.972 0.028
E16.3 Increased secretion of glucagon
0.000 0.972 0.028
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.028 0.972 0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)
0.028 0.972 0.000
E10.4 With neurological complications
0.000 0.972 0.028
E04.1 Non-toxic single thyroid nodule
0.027 0.973 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.973 0.027
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.027 0.973 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.027 0.973 0.000
E10.9 Without complications
0.000 0.973 0.027
D51 Vitamin B12 deficiency anaemia
0.000 0.973 0.027
M46.40 Discitis, unspecified (Multiple sites in spine)
0.027 0.973 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.973 0.027
E10-E14 Diabetes mellitus
0.000 0.974 0.026
E04.8 Other specified non-toxic goitre
0.025 0.974 0.001
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.974 0.026
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.026 0.974 0.000
C90.2 Plasmacytoma, extramedullary
0.000 0.974 0.026
M46.29 Osteomyelitis of vertebra (Site unspecified)
0.025 0.975 0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)
0.025 0.975 0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)
0.025 0.975 0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)
0.025 0.975 0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)
0.025 0.975 0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)
0.025 0.975 0.000
M46.22 Osteomyelitis of vertebra (Cervical region)
0.025 0.975 0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)
0.025 0.975 0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)
0.025 0.975 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.025 0.975 0.000
R04 Haemorrhage from respiratory passages
0.025 0.975 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.025 0.975 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.025 0.975 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.025 0.975 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.975 0.025
D50-D53 Nutritional anaemias
0.000 0.975 0.025
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.025 0.975 0.000
M06.8 Other specified rheumatoid arthritis
0.025 0.975 0.000
M06.2 Rheumatoid bursitis
0.025 0.975 0.000
E13 Other specified diabetes mellitus
0.000 0.976 0.024
M06.10 Adult-onset Still's disease (Multiple sites)
0.024 0.976 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.024 0.976 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.024 0.976 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.024 0.976 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.024 0.976 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.024 0.976 0.000
M46.42 Discitis, unspecified (Cervical region)
0.024 0.976 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.024 0.976 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.024 0.976 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.024 0.976 0.000
E13.9 Without complications
0.000 0.977 0.023
M06.08 Seronegative rheumatoid arthritis (Other)
0.023 0.977 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.023 0.977 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.023 0.977 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.023 0.977 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.023 0.977 0.000
M46.09 Spinal enthesopathy (Site unspecified)
0.023 0.977 0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)
0.023 0.977 0.000
M46.07 Spinal enthesopathy (Lumbosacral region)
0.023 0.977 0.000
M46.06 Spinal enthesopathy (Lumbar region)
0.023 0.977 0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)
0.023 0.977 0.000
M46.04 Spinal enthesopathy (Thoracic region)
0.023 0.977 0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)
0.023 0.977 0.000
M46.02 Spinal enthesopathy (Cervical region)
0.023 0.977 0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)
0.023 0.977 0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)
0.023 0.977 0.000
M46.59 Other infective spondylopathies (Site unspecified)
0.023 0.977 0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)
0.023 0.977 0.000
M46.57 Other infective spondylopathies (Lumbosacral region)
0.023 0.977 0.000
M46.56 Other infective spondylopathies (Lumbar region)
0.023 0.977 0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)
0.023 0.977 0.000
M46.54 Other infective spondylopathies (Thoracic region)
0.023 0.977 0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)
0.023 0.977 0.000
M46.52 Other infective spondylopathies (Cervical region)
0.023 0.977 0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)
0.023 0.977 0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)
0.023 0.977 0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)
0.023 0.977 0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)
0.023 0.977 0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)
0.023 0.977 0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)
0.023 0.977 0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)
0.023 0.977 0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)
0.023 0.977 0.000
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)
0.023 0.977 0.000
M46.82 Other specified inflammatory spondylopathies (Cervical region)
0.023 0.977 0.000
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)
0.023 0.977 0.000
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)
0.023 0.977 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.977 0.023
K93.1 Megacolon in Chagas' disease
0.000 0.977 0.023
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.977 0.023
M06.37 Rheumatoid nodule (Ankle and foot)
0.023 0.977 0.000
E04.0 Non-toxic diffuse goitre
0.022 0.977 0.001
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)
0.022 0.977 0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)
0.022 0.977 0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)
0.022 0.977 0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)
0.022 0.977 0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)
0.022 0.977 0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)
0.022 0.977 0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)
0.022 0.977 0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)
0.022 0.977 0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)
0.022 0.977 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.022 0.977 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.022 0.978 0.000
M06.38 Rheumatoid nodule (Other)
0.022 0.978 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.022 0.978 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.022 0.978 0.000
M06.33 Rheumatoid nodule (Forearm)
0.022 0.978 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.022 0.978 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.022 0.978 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.022 0.978 0.000
M49.4 Neuropathic spondylopathy
0.022 0.978 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.022 0.978 0.000
M49.2 Enterobacterial spondylitis
0.022 0.978 0.000
M49.1 Brucella spondylitis
0.022 0.978 0.000
M49.0 Tuberculosis of spine
0.022 0.978 0.000
C71 Malignant neoplasm of brain
0.022 0.978 0.000
M06.4 Inflammatory polyarthropathy
0.022 0.978 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.978 0.022
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)
0.021 0.978 0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe
0.021 0.979 0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral
0.021 0.979 0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar
0.021 0.979 0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar
0.021 0.979 0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic
0.021 0.979 0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic
0.021 0.979 0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical
0.021 0.979 0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl
0.021 0.979 0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site
0.021 0.979 0.000
D72.8 Other specified disorders of white blood cells
0.000 0.979 0.021
E05 Thyrotoxicosis [hyperthyroidism]
0.012 0.979 0.009
C71.0 Cerebrum, except lobes and ventricles
0.021 0.979 0.000
C71.9 Brain, unspecified
0.021 0.979 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.979 0.021
E83.8 Other disorders of mineral metabolism
0.000 0.979 0.021
E83.2 Disorders of zinc metabolism
0.000 0.979 0.021
E83.0 Disorders of copper metabolism
0.000 0.979 0.021
D72 Other disorders of white blood cells
0.000 0.979 0.021
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.979 0.020
M06.19 Adult-onset Still's disease (Site unspecified)
0.020 0.979 0.000
M06.18 Adult-onset Still's disease (Other)
0.020 0.979 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.020 0.979 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.020 0.979 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.020 0.979 0.000
M06.14 Adult-onset Still's disease (Hand)
0.020 0.979 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.020 0.979 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.020 0.979 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.020 0.979 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.979 0.020
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.020 0.979 0.000
D53 Other nutritional anaemias
0.000 0.980 0.020
E83.5 Disorders of calcium metabolism
0.000 0.980 0.020
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.020 0.980 0.000
C90.1 Plasma cell leukaemia
0.000 0.980 0.020
R04.2 Haemoptysis
0.020 0.980 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.981 0.019
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.981 0.019
D51.2 Transcobalamin II deficiency
0.000 0.981 0.019
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.981 0.019
C71.6 Cerebellum
0.019 0.981 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.981 0.019
C71.3 Parietal lobe
0.019 0.981 0.000
C90.3 Solitary plasmacytoma
0.000 0.981 0.019
M06.32 Rheumatoid nodule (Upper arm)
0.018 0.981 0.000
C71.4 Occipital lobe
0.019 0.981 0.000
E04.2 Non-toxic multinodular goitre
0.018 0.981 0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ
0.018 0.981 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.018 0.982 0.000
R04.1 Haemorrhage from throat
0.018 0.982 0.000
D70 Agranulocytosis
0.000 0.982 0.018
M06.29 Rheumatoid bursitis (Site unspecified)
0.018 0.982 0.000
M06.28 Rheumatoid bursitis (Other)
0.018 0.982 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.018 0.982 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.018 0.982 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.018 0.982 0.000
M06.24 Rheumatoid bursitis (Hand)
0.018 0.982 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.018 0.982 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.018 0.982 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.018 0.982 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.018 0.982 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.018 0.982 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.018 0.982 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.018 0.982 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.018 0.982 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.018 0.982 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.018 0.982 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.018 0.982 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.018 0.982 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.018 0.982 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.018 0.982 0.000
E13.8 With unspecified complications
0.000 0.982 0.018
E13.7 With multiple complications
0.000 0.982 0.018
E13.6 With other specified complications
0.000 0.982 0.018
E13.5 With peripheral circulatory complications
0.000 0.982 0.018
E13.4 With neurological complications
0.000 0.982 0.018
E13.2 With renal complications
0.000 0.982 0.018
E13.1 With ketoacidosis
0.000 0.982 0.018
E13.0 With coma
0.000 0.982 0.018
M48 Other spondylopathies
0.017 0.982 0.000
D53.9 Nutritional anaemia, unspecified
0.000 0.983 0.017
M49.5 Collapsed vertebra in diseases classified elsewhere
0.017 0.983 0.000
E13.3 With ophthalmic complications
0.000 0.983 0.017
E70-E90 Metabolic disorders
0.000 0.983 0.017
C71.2 Temporal lobe
0.017 0.983 0.000
E88 Other metabolic disorders
0.000 0.983 0.017
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.984 0.016
H40.2 Primary angle-closure glaucoma
0.016 0.984 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.016 0.984 0.000
M49.09 Tuberculosis of spine (Site unspecified)
0.016 0.984 0.000
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.016 0.984 0.000
M49.07 Tuberculosis of spine (Lumbosacral region)
0.016 0.984 0.000
M49.06 Tuberculosis of spine (Lumbar region)
0.016 0.984 0.000
M49.05 Tuberculosis of spine (Thoracolumbar region)
0.016 0.984 0.000
M49.04 Tuberculosis of spine (Thoracic region)
0.016 0.984 0.000
M49.03 Tuberculosis of spine (Cervicothoracic region)
0.016 0.984 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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