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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2394450
log Bayes Factor = 57.2005
Chromosome 6   position 30,817,501  (GRCh37) Explore rs2394450 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
E11.9 Without complications
0.000 0.001 0.999
M06.9 Rheumatoid arthritis, unspecified
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E11 Non-insulin-dependent diabetes mellitus
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.003 0.997
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.012 0.988
E10.4 With neurological complications
0.000 0.020 0.980
E10.5 With peripheral circulatory complications
0.000 0.022 0.978
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.030 0.970
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.037 0.963
E16 Other disorders of pancreatic internal secretion
0.000 0.052 0.948
E14 Unspecified diabetes mellitus
0.000 0.055 0.945
E10.1 With ketoacidosis
0.000 0.057 0.943
E16.2 Hypoglycaemia, unspecified
0.000 0.084 0.916
L40.9 Psoriasis, unspecified
0.905 0.095 0.000
E10.2 With renal complications
0.000 0.097 0.903
E14.3 With ophthalmic complications
0.000 0.120 0.880
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.120 0.880
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.121 0.879
E11.0 With coma
0.000 0.139 0.861
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.173 0.827
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.179 0.821
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.185 0.815
E10.0 With coma
0.000 0.191 0.809
E14.8 With unspecified complications
0.000 0.202 0.798
E14.6 With other specified complications
0.000 0.204 0.796
E50-E64 Other nutritional deficiencies
0.000 0.205 0.795
E11.5 With peripheral circulatory complications
0.000 0.217 0.783
E11.6 With other specified complications
0.000 0.223 0.777
E10.6 With other specified complications
0.000 0.224 0.776
E10.7 With multiple complications
0.000 0.224 0.776
L40 Psoriasis
0.747 0.253 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.265 0.735
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.270 0.730
E13 Other specified diabetes mellitus
0.000 0.271 0.729
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.284 0.716
E14.1 With ketoacidosis
0.000 0.285 0.715
E07 Other disorders of thyroid
0.000 0.288 0.712
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.294 0.706
E14.2 Withrenal complications
0.000 0.301 0.699
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.302 0.698
E15 Nondiabetic hypoglycaemic coma
0.000 0.305 0.695
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.307 0.693
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.318 0.682
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.320 0.680
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.320 0.680
E16.4 Abnormal secretion of gastrin
0.000 0.320 0.680
E16.3 Increased secretion of glucagon
0.000 0.320 0.680
E06 Thyroiditis
0.000 0.320 0.680
E14.7 With multiple complications
0.000 0.322 0.677
E14.0 With coma
0.000 0.322 0.677
E16.1 Other hypoglycaemia
0.000 0.324 0.676
E11.3 With ophthalmic complications
0.000 0.328 0.672
E10.8 With unspecified complications
0.000 0.328 0.672
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.340 0.660
E21.3 Hyperparathyroidism, unspecified
0.000 0.344 0.656
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.356 0.644
E03.1 Congenital hypothyroidism without goitre
0.000 0.359 0.641
L40.0 Psoriasis vulgaris
0.641 0.359 0.000
E05.8 Other thyrotoxicosis
0.000 0.366 0.634
E11.8 With unspecified complications
0.000 0.370 0.629
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.371 0.629
E51 Thiamine deficiency
0.000 0.384 0.616
K90 Intestinal malabsorption
0.000 0.386 0.614
E58 Dietary calcium deficiency
0.000 0.387 0.613
E55 Vitamin D deficiency
0.000 0.390 0.610
L40.8 Other psoriasis
0.609 0.391 0.000
E53 Deficiency of other B group vitamins
0.000 0.394 0.606
M35.0 Sicca syndrome [Sjogren]
0.000 0.397 0.603
E21.0 Primary hyperparathyroidism
0.000 0.404 0.596
E14.5 With peripheral circulatory complications
0.000 0.404 0.596
E22 Hyperfunction of pituitary gland
0.000 0.405 0.595
E14.9 Without complications
0.000 0.414 0.586
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.430 0.570
E63 Other nutritional deficiencies
0.000 0.430 0.570
E50 Vitamin A deficiency
0.000 0.430 0.570
E60 Dietary zinc deficiency
0.000 0.430 0.570
E59 Dietary selenium deficiency
0.000 0.430 0.570
E54 Ascorbic acid deficiency
0.000 0.430 0.570
E52 Niacin deficiency [pellagra]
0.000 0.430 0.570
L40.3 Pustulosis palmaris et plantaris
0.569 0.430 0.000
E56 Other vitamin deficiencies
0.000 0.438 0.562
L40.5 Arthropathic psoriasis
0.561 0.439 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.439 0.561
E14.4 With neurological complications
0.000 0.440 0.559
E40-E46 Malnutrition
0.000 0.442 0.557
E13.9 Without complications
0.000 0.443 0.557
E24 Cushing's syndrome
0.000 0.448 0.552
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.456 0.543
L40.1 Generalised pustular psoriasis
0.542 0.458 0.000
E03.8 Other specified hypothyroidism
0.000 0.462 0.538
L40.4 Guttate psoriasis
0.536 0.464 0.000
L40.2 Acrodermatitis continua
0.536 0.464 0.000
E06.5 Other chronic thyroiditis
0.000 0.465 0.535
E31 Polyglandular dysfunction
0.000 0.467 0.533
E23 Hypofunction and other disorders of pituitary gland
0.000 0.470 0.530
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.473 0.527
E32 Diseases of thymus
0.000 0.473 0.527
E30 Disorders of puberty, not elsewhere classified
0.000 0.473 0.527
E13.8 With unspecified complications
0.000 0.477 0.523
E13.7 With multiple complications
0.000 0.477 0.523
E13.6 With other specified complications
0.000 0.477 0.523
E13.5 With peripheral circulatory complications
0.000 0.477 0.523
E13.4 With neurological complications
0.000 0.477 0.523
E13.2 With renal complications
0.000 0.477 0.523
E13.1 With ketoacidosis
0.000 0.477 0.523
E13.0 With coma
0.000 0.477 0.523
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E07.1 Dyshormogenetic goitre
0.000 0.489 0.510
E07.0 Hypersecretion of calcitonin
0.000 0.489 0.510
E22.1 Hyperprolactinaemia
0.000 0.491 0.509
E11.1 With ketoacidosis
0.000 0.499 0.501
E27 Other disorders of adrenal gland
0.000 0.499 0.501
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.501 0.499
E53.8 Deficiency of other specified B group vitamins
0.000 0.502 0.498
E13.3 With ophthalmic complications
0.000 0.504 0.496
E21.2 Other hyperparathyroidism
0.000 0.507 0.493
E28 Ovarian dysfunction
0.000 0.508 0.492
E06.4 Drug-induced thyroiditis
0.000 0.512 0.487
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.512 0.487
E06.0 Acute thyroiditis
0.000 0.512 0.487
E51.2 Wernicke's encephalopathy
0.000 0.513 0.487
E06.9 Thyroiditis, unspecified
0.000 0.517 0.483
E55.9 Vitamin D deficiency, unspecified
0.000 0.522 0.478
E20 Hypoparathyroidism
0.000 0.522 0.478
E61 Deficiency of other nutrient elements
0.000 0.526 0.474
E27.1 Primary adrenocortical insufficiency
0.000 0.531 0.469
E21.4 Other specified disorders of parathyroid gland
0.000 0.538 0.461
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.541 0.459
E25 Adrenogenital disorders
0.000 0.544 0.456
E06.1 Subacute thyroiditis
0.000 0.545 0.454
E11.2 With renal complications
0.000 0.550 0.450
K90.9 Intestinal malabsorption, unspecified
0.000 0.553 0.447
E51.9 Thiamine deficiency, unspecified
0.000 0.558 0.441
E51.8 Other manifestations of thiamine deficiency
0.000 0.558 0.441
E51.1 Beriberi
0.000 0.558 0.441
E34 Other endocrine disorders
0.000 0.559 0.441
K90.3 Pancreatic steatorrhoea
0.000 0.560 0.440
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.560 0.440
K90.1 Tropical sprue
0.000 0.560 0.440
E55.0 Rickets, active
0.000 0.562 0.438
E07.8 Other specified disorders of thyroid
0.000 0.563 0.437
E53.1 Pyridoxine deficiency
0.000 0.565 0.435
E53.0 Riboflavin deficiency
0.000 0.565 0.435
E29 Testicular dysfunction
0.000 0.570 0.430
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.573 0.427
E22.8 Other hyperfunction of pituitary gland
0.000 0.573 0.427
E06.3 Autoimmune thyroiditis
0.000 0.574 0.426
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.574 0.426
E65-E68 Obesity and other hyperalimentation
0.000 0.579 0.420
E23.0 Hypopituitarism
0.000 0.582 0.418
M35 Other systemic involvement of connective tissue
0.000 0.585 0.415
E24.2 Drug-induced Cushing's syndrome
0.000 0.590 0.410
E50.9 Vitamin A deficiency, unspecified
0.000 0.591 0.409
E50.8 Other manifestations of vitamin A deficiency
0.000 0.591 0.409
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.591 0.409
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.591 0.409
E50.5 Vitamin A deficiency with night blindness
0.000 0.591 0.409
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.591 0.409
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.591 0.409
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.591 0.409
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.591 0.409
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.591 0.409
E63.9 Nutritional deficiency, unspecified
0.000 0.591 0.409
E63.8 Other specified nutritional deficiencies
0.000 0.591 0.409
E63.1 Imbalance of constituents of food intake
0.000 0.591 0.409
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.591 0.409
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.591 0.409
E64.8 Sequelae of other nutritional deficiencies
0.000 0.591 0.409
E64.3 Sequelae of rickets
0.000 0.591 0.409
E64.2 Sequelae of vitamin C deficiency
0.000 0.591 0.409
E64.1 Sequelae of vitamin A deficiency
0.000 0.591 0.409
E64.0 Sequelae of protein-energy malnutrition
0.000 0.591 0.409
M06 Other rheumatoid arthritis
0.000 0.592 0.408
E24.9 Cushing's syndrome, unspecified
0.000 0.596 0.404
E56.9 Vitamin deficiency, unspecified
0.000 0.597 0.403
E56.8 Deficiency of other vitamins
0.000 0.597 0.403
E56.0 Deficiency of vitamin E
0.000 0.597 0.403
E24.0 Pituitary-dependent Cushing's disease
0.000 0.599 0.401
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.600 0.400
E45 Retarded development following protein-energy malnutrition
0.000 0.600 0.400
E43 Unspecified severe protein-energy malnutrition
0.000 0.600 0.400
E42 Marasmic kwashiorkor
0.000 0.600 0.400
E41 Nutritional marasmus
0.000 0.600 0.400
E40 Kwashiorkor
0.000 0.600 0.400
K90.8 Other intestinal malabsorption
0.000 0.600 0.400
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.601 0.399
E24.8 Other Cushing's syndrome
0.000 0.604 0.396
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.604 0.396
E24.3 Ectopic ACTH syndrome
0.000 0.604 0.396
E24.1 Nelson's syndrome
0.000 0.604 0.396
E56.1 Deficiency of vitamin K
0.000 0.605 0.395
E53.9 Vitamin B deficiency, unspecified
0.000 0.608 0.392
E31.0 Autoimmune polyglandular failure
0.000 0.611 0.389
E31.9 Polyglandular dysfunction, unspecified
0.000 0.617 0.382
E31.8 Other polyglandular dysfunction
0.000 0.617 0.382
E31.1 Polyglandular hyperfunction
0.000 0.617 0.382
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.620 0.380
E23.1 Drug-induced hypopituitarism
0.000 0.620 0.380
E30.9 Disorder of puberty, unspecified
0.000 0.622 0.378
E30.8 Other disorders of puberty
0.000 0.622 0.378
E30.1 Precocious puberty
0.000 0.622 0.378
E30.0 Delayed puberty
0.000 0.622 0.378
E32.9 Disease of thymus, unspecified
0.000 0.622 0.378
E32.8 Other diseases of thymus
0.000 0.622 0.378
E32.1 Abscess of thymus
0.000 0.622 0.378
E32.0 Persistent hyperplasia of thymus
0.000 0.622 0.378
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.622 0.378
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.622 0.378
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.622 0.378
E23.7 Disorder of pituitary gland, unspecified
0.000 0.626 0.374
E23.2 Diabetes insipidus
0.000 0.631 0.369
E28.3 Primary ovarian failure
0.000 0.633 0.367
M35.1 Other overlap syndromes
0.000 0.639 0.361
E27.5 Adrenomedullary hyperfunction
0.000 0.641 0.359
E27.0 Other adrenocortical overactivity
0.000 0.641 0.359
E26 Hyperaldosteronism
0.000 0.641 0.358
M06.4 Inflammatory polyarthropathy
0.000 0.645 0.355
E22.0 Acromegaly and pituitary gigantism
0.000 0.646 0.354
E23.6 Other disorders of pituitary gland
0.000 0.647 0.353
E28.9 Ovarian dysfunction, unspecified
0.000 0.647 0.353
E28.8 Other ovarian dysfunction
0.000 0.647 0.353
E28.1 Androgen excess
0.000 0.647 0.353
E28.0 Oestrogen excess
0.000 0.647 0.353
M35.2 Behcet's disease
0.000 0.647 0.353
E20.8 Other hypoparathyroidism
0.000 0.657 0.343
E20.1 Pseudohypoparathyroidism
0.000 0.657 0.343
E20.0 Idiopathic hypoparathyroidism
0.000 0.657 0.343
E61.9 Deficiency of nutrient element, unspecified
0.000 0.660 0.340
E61.8 Deficiency of other specified nutrient elements
0.000 0.660 0.340
E61.7 Deficiency of multiple nutrient elements
0.000 0.660 0.340
E61.6 Vanadium deficiency
0.000 0.660 0.340
E61.5 Molybdenum deficiency
0.000 0.660 0.340
E61.4 Chromium deficiency
0.000 0.660 0.340
E61.3 Manganese deficiency
0.000 0.660 0.340
E61.0 Copper deficiency
0.000 0.660 0.340
E27.2 Addisonian crisis
0.000 0.672 0.328
E25.9 Adrenogenital disorder, unspecified
0.000 0.673 0.327
E25.8 Other adrenogenital disorders
0.000 0.673 0.327
E34.3 Short stature, not elsewhere classified
0.000 0.676 0.324
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.678 0.322
E34.5 Androgen resistance syndrome
0.000 0.684 0.316
E34.4 Constitutional tall stature
0.000 0.684 0.316
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.684 0.316
E34.1 Other hypersecretion of intestinal hormones
0.000 0.684 0.316
E34.8 Other specified endocrine disorders
0.000 0.685 0.315
E29.9 Testicular dysfunction, unspecified
0.000 0.692 0.308
E29.8 Other testicular dysfunction
0.000 0.692 0.308
E29.0 Testicular hyperfunction
0.000 0.692 0.308
E04 Other non-toxic goitre
0.000 0.693 0.307
M35.3 Polymyalgia rheumatica
0.000 0.694 0.306
E61.1 Iron deficiency
0.000 0.695 0.305
E67 Other hyperalimentation
0.000 0.698 0.301
E68 Sequelae of hyperalimentation
0.000 0.698 0.301
E11.4 With neurological complications
0.000 0.700 0.300
E28.2 Polycystic ovarian syndrome
0.000 0.701 0.299
M35.7 Hypermobility syndrome
0.000 0.702 0.298
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.702 0.297
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.702 0.297
M35.5 Multifocal fibrosclerosis
0.000 0.702 0.297
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.702 0.297
E34.9 Endocrine disorder, unspecified
0.000 0.703 0.297
E20.9 Hypoparathyroidism, unspecified
0.000 0.705 0.294
M06.8 Other specified rheumatoid arthritis
0.000 0.707 0.293
M06.2 Rheumatoid bursitis
0.000 0.707 0.293
M06.1 Adult-onset Still's disease
0.000 0.707 0.293
E61.2 Magnesium deficiency
0.000 0.708 0.292
E44.1 Mild protein-energy malnutrition
0.000 0.713 0.287
E44.0 Moderate protein-energy malnutrition
0.000 0.713 0.287
L40-L45 Papulosquamous disorders
0.273 0.727 0.000
M06.3 Rheumatoid nodule
0.000 0.729 0.271
E26.8 Other hyperaldosteronism
0.000 0.743 0.257
E26.1 Secondary hyperaldosteronism
0.000 0.743 0.257
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.743 0.256
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.746 0.254
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.746 0.254
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.746 0.254
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.746 0.254
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.746 0.254
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.746 0.254
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.746 0.254
E27.9 Disorder of adrenal gland, unspecified
0.000 0.749 0.250
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.750 0.250
E34.0 Carcinoid syndrome
0.000 0.751 0.248
E27.8 Other specified disorders of adrenal gland
0.000 0.753 0.247
M35.8 Other specified systemic involvement of connective tissue
0.000 0.758 0.242
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.759 0.241
E46 Unspecified protein-energy malnutrition
0.000 0.759 0.240
E04.9 Non-toxic goitre, unspecified
0.000 0.762 0.238
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.767 0.233
E04.0 Non-toxic diffuse goitre
0.000 0.770 0.230
L42 Pityriasis rosea
0.229 0.771 0.000
E26.9 Hyperaldosteronism, unspecified
0.001 0.778 0.221
E04.8 Other specified non-toxic goitre
0.000 0.780 0.220
E66 Obesity
0.000 0.780 0.220
E67.8 Other specified hyperalimentation
0.000 0.783 0.216
E67.3 Hypervitaminosis D
0.000 0.783 0.216
E67.2 Megavitamin-B6 syndrome
0.000 0.783 0.216
E67.1 Hypercarotenaemia
0.000 0.783 0.216
E67.0 Hypervitaminosis A
0.000 0.783 0.216
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.786 0.213
E29.1 Testicular hypofunction
0.000 0.788 0.211
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.789 0.211
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.789 0.210
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.789 0.210
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.789 0.210
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.789 0.210
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.789 0.210
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.789 0.210
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.789 0.210
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.789 0.210
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.789 0.210
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.790 0.210
M06.18 Adult-onset Still's disease (Other)
0.000 0.790 0.210
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.790 0.210
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.790 0.210
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.790 0.210
M06.14 Adult-onset Still's disease (Hand)
0.000 0.790 0.210
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.790 0.210
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.790 0.210
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.790 0.210
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.790 0.210
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.790 0.210
M06.28 Rheumatoid bursitis (Other)
0.000 0.790 0.210
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.790 0.210
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.790 0.210
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.790 0.210
M06.24 Rheumatoid bursitis (Hand)
0.000 0.790 0.210
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.790 0.210
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.790 0.210
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.790 0.210
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.790 0.210
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.793 0.207
M06.34 Rheumatoid nodule (Hand)
0.000 0.800 0.199
L44 Other papulosquamous disorders
0.196 0.804 0.000
L41 Parapsoriasis
0.196 0.804 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.196 0.804 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.806 0.194
M06.38 Rheumatoid nodule (Other)
0.000 0.806 0.194
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.806 0.194
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.806 0.194
M06.33 Rheumatoid nodule (Forearm)
0.000 0.806 0.194
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.806 0.194
E66.8 Other obesity
0.000 0.811 0.189
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.820 0.180
E65 Localised adiposity
0.001 0.825 0.174
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.836 0.163
E26.0 Primary hyperaldosteronism
0.001 0.841 0.158
E66.1 Drug-induced obesity
0.000 0.842 0.158
E66.0 Obesity due to excess calories
0.000 0.852 0.148
L41.9 Parapsoriasis, unspecified
0.140 0.859 0.000
L41.8 Other parapsoriasis
0.140 0.859 0.000
L41.5 Retiform parapsoriasis
0.140 0.859 0.000
L41.4 Large plaque parapsoriasis
0.140 0.859 0.000
L41.3 Small plaque parapsoriasis
0.140 0.859 0.000
L41.2 Lymphomatoid papulosis
0.140 0.859 0.000
L41.1 Pityriasis lichenoides chronica
0.140 0.859 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.140 0.859 0.000
L44.9 Papulosquamous disorder, unspecified
0.140 0.859 0.000
L44.8 Other specified papulosquamous disorders
0.140 0.859 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.140 0.859 0.000
L44.3 Lichen ruber moniliformis
0.140 0.859 0.000
L44.2 Lichen striatus
0.140 0.859 0.000
L44.1 Lichen nitidus
0.140 0.859 0.000
L44.0 Pityriasis rubra pilaris
0.140 0.859 0.000
M05-M14 Inflammatory polyarthropathies
0.000 0.875 0.125
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.878 0.121
M05 Seropositive rheumatoid arthritis
0.000 0.879 0.120
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.883 0.117
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.885 0.115
L43 Lichen planus
0.102 0.897 0.001
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.902 0.098
M12 Other specific arthropathies
0.000 0.903 0.097
M06.0 Seronegative rheumatoid arthritis
0.001 0.904 0.095
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.909 0.091
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.910 0.090
M05.8 Other seropositive rheumatoid arthritis
0.000 0.910 0.089
M08 Juvenile arthritis
0.000 0.913 0.087
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.913 0.086
M05.1 Rheumatoid lung disease
0.000 0.913 0.086
M05.0 Felty's syndrome
0.000 0.913 0.086
M05.2 Rheumatoid vasculitis
0.000 0.914 0.085
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.916 0.084
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.916 0.084
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.916 0.084
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.916 0.084
M10 Gout
0.000 0.918 0.081
M14 Arthropathies in other diseases classified elsewhere
0.000 0.919 0.081
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.922 0.078
M12.3 Palindromic rheumatism
0.000 0.923 0.077
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.924 0.076
E04.2 Non-toxic multinodular goitre
0.000 0.924 0.076
L43.3 Subacute (active) lichen planus
0.074 0.926 0.001
L43.2 Lichenoid drug reaction
0.074 0.926 0.001
L43.1 Bullous lichen planus
0.074 0.926 0.001
L43.0 Hypertrophic lichen planus
0.074 0.926 0.001
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.001 0.927 0.072
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.927 0.073
M11 Other crystal arthropathies
0.000 0.928 0.072
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.928 0.071
M12.5 Traumatic arthropathy
0.000 0.929 0.071
M12.4 Intermittent hydrarthrosis
0.000 0.930 0.070
M12.1 Kaschin-Beck disease
0.000 0.930 0.070
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.930 0.070
M06.08 Seronegative rheumatoid arthritis (Other)
0.001 0.931 0.068
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.001 0.931 0.068
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.001 0.931 0.068
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.001 0.931 0.068
M10.0 Idiopathic gout
0.000 0.931 0.069
M06.04 Seronegative rheumatoid arthritis (Hand)
0.001 0.932 0.067
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.933 0.067
M12.2 Villonodular synovitis (pigmented)
0.000 0.934 0.066
L43.8 Other lichen planus
0.065 0.934 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.935 0.065
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.935 0.065
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.935 0.065
M09.0 Juvenile arthritis in psoriasis
0.000 0.935 0.065
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.935 0.064
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.935 0.064
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.935 0.064
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.935 0.064
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.935 0.064
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.935 0.064
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.935 0.064
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.935 0.064
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.935 0.064
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.935 0.064
M08.9 Juvenile arthritis, unspecified
0.000 0.937 0.063
M08.8 Other juvenile arthritis
0.000 0.937 0.063
M08.4 Pauciarticular juvenile arthritis
0.000 0.937 0.063
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.937 0.063
M08.2 Juvenile arthritis with systemic onset
0.000 0.937 0.063
M08.1 Juvenile ankylosing spondylitis
0.000 0.937 0.063
M05.09 Felty's syndrome (Site unspecified)
0.000 0.938 0.062
M05.08 Felty's syndrome (Other)
0.000 0.938 0.062
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.938 0.062
M05.06 Felty's syndrome (Lower leg)
0.000 0.938 0.062
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.938 0.062
M05.04 Felty's syndrome (Hand)
0.000 0.938 0.062
M05.03 Felty's syndrome (Forearm)
0.000 0.938 0.062
M05.02 Felty's syndrome (Upper arm)
0.000 0.938 0.062
M05.01 Felty's syndrome (Shoulder region)
0.000 0.938 0.062
M05.00 Felty's syndrome (Multiple sites)
0.000 0.938 0.062
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.938 0.062
M05.18 Rheumatoid lung disease (Other)
0.000 0.938 0.062
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.938 0.062
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.938 0.062
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.938 0.062
M05.14 Rheumatoid lung disease (Hand)
0.000 0.938 0.062
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.938 0.062
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.938 0.062
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.938 0.062
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.938 0.062
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.938 0.062
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.938 0.062
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.938 0.062
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.938 0.062
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.938 0.062
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.938 0.062
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.938 0.062
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.938 0.062

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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