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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2394609
log Bayes Factor = 37.9354
Chromosome 6   position 29,398,000  (GRCh37) Explore rs2394609 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.005 0.995
E10.3 With ophthalmic complications
0.000 0.015 0.985
E10.9 Without complications
0.000 0.022 0.978
E10.2 With renal complications
0.000 0.037 0.963
E10.1 With ketoacidosis
0.000 0.046 0.954
E10-E14 Diabetes mellitus
0.000 0.074 0.926
E13 Other specified diabetes mellitus
0.000 0.091 0.909
E10.4 With neurological complications
0.000 0.095 0.905
E13.9 Without complications
0.000 0.103 0.897
E10.0 With coma
0.000 0.207 0.793
E14 Unspecified diabetes mellitus
0.000 0.245 0.755
E10.6 With other specified complications
0.000 0.252 0.748
E10.5 With peripheral circulatory complications
0.000 0.267 0.733
E10.7 With multiple complications
0.000 0.280 0.720
E12 Malnutrition-related diabetes mellitus
0.000 0.336 0.664
E13.8 With unspecified complications
0.000 0.348 0.652
E13.7 With multiple complications
0.000 0.348 0.652
E13.6 With other specified complications
0.000 0.348 0.652
E13.5 With peripheral circulatory complications
0.000 0.348 0.652
E13.4 With neurological complications
0.000 0.348 0.652
E13.2 With renal complications
0.000 0.348 0.652
E13.1 With ketoacidosis
0.000 0.348 0.652
E13.0 With coma
0.000 0.348 0.652
E13.3 With ophthalmic complications
0.000 0.352 0.647
E14.9 Without complications
0.000 0.368 0.632
E14.2 Withrenal complications
0.000 0.414 0.586
E14.4 With neurological complications
0.000 0.442 0.558
E14.8 With unspecified complications
0.000 0.448 0.552
E14.1 With ketoacidosis
0.000 0.451 0.549
E14.7 With multiple complications
0.000 0.459 0.541
E14.6 With other specified complications
0.000 0.459 0.541
E14.5 With peripheral circulatory complications
0.000 0.459 0.541
E14.0 With coma
0.000 0.459 0.541
E10.8 With unspecified complications
0.000 0.473 0.527
K90 Intestinal malabsorption
0.000 0.501 0.499
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.519 0.481
E12.9 Without complications
0.000 0.524 0.476
E12.8 With unspecified complications
0.000 0.524 0.476
E12.7 With multiple complications
0.000 0.524 0.476
E12.6 With other specified complications
0.000 0.524 0.476
E12.5 With peripheral circulatory complications
0.000 0.524 0.476
E12.4 With neurological complications
0.000 0.524 0.476
E12.3 With ophthalmic complications
0.000 0.524 0.476
E12.2 With renal complications
0.000 0.524 0.476
E12.1 With ketoacidosis
0.000 0.524 0.476
E12.0 With coma
0.000 0.524 0.476
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.525 0.475
E16 Other disorders of pancreatic internal secretion
0.000 0.529 0.471
E16.2 Hypoglycaemia, unspecified
0.000 0.532 0.468
E14.3 With ophthalmic complications
0.000 0.566 0.434
E00-E07 Disorders of thyroid gland
0.000 0.569 0.431
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.574 0.426
E05.9 Thyrotoxicosis, unspecified
0.000 0.582 0.418
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.598 0.402
E16.1 Other hypoglycaemia
0.000 0.601 0.399
K51 Ulcerative colitis
0.378 0.622 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.625 0.375
K51.9 Ulcerative colitis, unspecified
0.370 0.630 0.000
K51.4 Pseudopolyposis of colon
0.366 0.634 0.000
E05.8 Other thyrotoxicosis
0.000 0.637 0.363
K90.3 Pancreatic steatorrhoea
0.000 0.642 0.358
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.642 0.358
K90.1 Tropical sprue
0.000 0.642 0.358
K90.9 Intestinal malabsorption, unspecified
0.000 0.646 0.354
K51.2 Ulcerative (chronic) proctitis
0.353 0.647 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.352 0.648 0.000
K90.8 Other intestinal malabsorption
0.000 0.652 0.348
E15 Nondiabetic hypoglycaemic coma
0.000 0.659 0.340
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.662 0.338
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.662 0.338
E16.4 Abnormal secretion of gastrin
0.000 0.662 0.338
E16.3 Increased secretion of glucagon
0.000 0.662 0.338
K51.0 Ulcerative (chronic) enterocolitis
0.323 0.677 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.680 0.320
E40-E46 Malnutrition
0.000 0.684 0.316
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.691 0.309
E00 Congenital iodine-deficiency syndrome
0.000 0.691 0.309
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.694 0.306
E05.5 Thyroid crisis or storm
0.000 0.694 0.306
E05.4 Thyrotoxicosis factitia
0.000 0.694 0.306
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.694 0.306
E07 Other disorders of thyroid
0.000 0.718 0.282
K51.1 Ulcerative (chronic) ileocolitis
0.280 0.720 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.726 0.274
K51.8 Other ulcerative colitis
0.272 0.728 0.000
K51.5 Mucosal proctocolitis
0.267 0.733 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.739 0.261
E20-E35 Disorders of other endocrine glands
0.000 0.747 0.253
E11.2 With renal complications
0.000 0.759 0.241
E83 Disorders of mineral metabolism
0.238 0.762 0.000
E11.0 With coma
0.000 0.763 0.237
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.764 0.236
E04 Other non-toxic goitre
0.000 0.768 0.232
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.773 0.227
E45 Retarded development following protein-energy malnutrition
0.000 0.773 0.227
E43 Unspecified severe protein-energy malnutrition
0.000 0.773 0.227
E42 Marasmic kwashiorkor
0.000 0.773 0.227
E41 Nutritional marasmus
0.000 0.773 0.227
E40 Kwashiorkor
0.000 0.773 0.227
E50-E64 Other nutritional deficiencies
0.000 0.773 0.227
E04.9 Non-toxic goitre, unspecified
0.000 0.775 0.225
E23 Hypofunction and other disorders of pituitary gland
0.000 0.776 0.224
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.778 0.221
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.778 0.221
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.778 0.221
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.778 0.221
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.778 0.221
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.778 0.221
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.778 0.221
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.778 0.221
E03 Other hypothyroidism
0.000 0.778 0.222
E07.8 Other specified disorders of thyroid
0.000 0.779 0.221
E06 Thyroiditis
0.000 0.788 0.212
E11.6 With other specified complications
0.000 0.789 0.211
E24 Cushing's syndrome
0.000 0.792 0.207
E20 Hypoparathyroidism
0.000 0.795 0.205
E07.1 Dyshormogenetic goitre
0.000 0.798 0.202
E07.0 Hypersecretion of calcitonin
0.000 0.798 0.202
E46 Unspecified protein-energy malnutrition
0.000 0.801 0.198
E11.7 With multiple complications
0.000 0.803 0.197
E23.0 Hypopituitarism
0.000 0.805 0.195
E23.2 Diabetes insipidus
0.000 0.806 0.194
E29 Testicular dysfunction
0.000 0.812 0.188
E83.3 Disorders of phosphorus metabolism
0.184 0.816 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.818 0.181
E32 Diseases of thymus
0.000 0.818 0.181
E30 Disorders of puberty, not elsewhere classified
0.000 0.818 0.181
E25 Adrenogenital disorders
0.000 0.818 0.181
E51 Thiamine deficiency
0.000 0.822 0.177
E11.1 With ketoacidosis
0.000 0.823 0.177
E03.8 Other specified hypothyroidism
0.000 0.825 0.175
E24.9 Cushing's syndrome, unspecified
0.000 0.829 0.171
E83.9 Disorder of mineral metabolism, unspecified
0.171 0.829 0.000
E83.8 Other disorders of mineral metabolism
0.171 0.829 0.000
E83.2 Disorders of zinc metabolism
0.171 0.829 0.000
E83.0 Disorders of copper metabolism
0.171 0.829 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.829 0.170
E22 Hyperfunction of pituitary gland
0.000 0.831 0.169
E56 Other vitamin deficiencies
0.000 0.831 0.169
E06.9 Thyroiditis, unspecified
0.000 0.832 0.168
E04.8 Other specified non-toxic goitre
0.000 0.833 0.166
E11.8 With unspecified complications
0.000 0.834 0.166
E31 Polyglandular dysfunction
0.000 0.835 0.165
E65-E68 Obesity and other hyperalimentation
0.000 0.835 0.165
E03.1 Congenital hypothyroidism without goitre
0.000 0.836 0.164
E44.1 Mild protein-energy malnutrition
0.000 0.837 0.163
E44.0 Moderate protein-energy malnutrition
0.000 0.837 0.163
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.837 0.163
E63 Other nutritional deficiencies
0.000 0.837 0.163
E50 Vitamin A deficiency
0.000 0.837 0.163
E60 Dietary zinc deficiency
0.000 0.837 0.163
E59 Dietary selenium deficiency
0.000 0.837 0.163
E54 Ascorbic acid deficiency
0.000 0.837 0.163
E52 Niacin deficiency [pellagra]
0.000 0.837 0.163
E28 Ovarian dysfunction
0.000 0.838 0.162
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.839 0.161
E23.1 Drug-induced hypopituitarism
0.000 0.839 0.161
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.840 0.160
E83.4 Disorders of magnesium metabolism
0.159 0.841 0.000
E03.5 Myxoedema coma
0.000 0.841 0.159
E03.4 Atrophy of thyroid (acquired)
0.000 0.841 0.159
E03.3 Postinfectious hypothyroidism
0.000 0.841 0.159
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.841 0.159
E11.4 With neurological complications
0.000 0.841 0.159
E11.5 With peripheral circulatory complications
0.000 0.842 0.158
E24.2 Drug-induced Cushing's syndrome
0.000 0.845 0.155
E06.4 Drug-induced thyroiditis
0.000 0.848 0.152
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.848 0.152
E06.1 Subacute thyroiditis
0.000 0.848 0.152
E06.0 Acute thyroiditis
0.000 0.848 0.152
E24.8 Other Cushing's syndrome
0.000 0.851 0.149
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.851 0.149
E24.3 Ectopic ACTH syndrome
0.000 0.851 0.149
E24.1 Nelson's syndrome
0.000 0.851 0.149
E24.0 Pituitary-dependent Cushing's disease
0.000 0.851 0.149
E23.7 Disorder of pituitary gland, unspecified
0.000 0.852 0.148
E20.8 Other hypoparathyroidism
0.000 0.853 0.147
E20.1 Pseudohypoparathyroidism
0.000 0.853 0.147
E20.0 Idiopathic hypoparathyroidism
0.000 0.853 0.147
E34 Other endocrine disorders
0.000 0.854 0.146
E58 Dietary calcium deficiency
0.000 0.854 0.145
E26 Hyperaldosteronism
0.000 0.855 0.145
E53 Deficiency of other B group vitamins
0.000 0.856 0.144
E51.2 Wernicke's encephalopathy
0.000 0.858 0.142
E29.1 Testicular hypofunction
0.000 0.858 0.142
E23.6 Other disorders of pituitary gland
0.000 0.858 0.142
E07.9 Disorder of thyroid, unspecified
0.000 0.859 0.141
E55 Vitamin D deficiency
0.000 0.863 0.137
E29.9 Testicular dysfunction, unspecified
0.000 0.865 0.135
E29.8 Other testicular dysfunction
0.000 0.865 0.135
E29.0 Testicular hyperfunction
0.000 0.865 0.135
E22.0 Acromegaly and pituitary gigantism
0.000 0.867 0.133
E25.9 Adrenogenital disorder, unspecified
0.000 0.870 0.130
E25.8 Other adrenogenital disorders
0.000 0.870 0.130
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.870 0.130
E30.9 Disorder of puberty, unspecified
0.000 0.870 0.130
E30.8 Other disorders of puberty
0.000 0.870 0.130
E30.1 Precocious puberty
0.000 0.870 0.130
E30.0 Delayed puberty
0.000 0.870 0.130
E32.9 Disease of thymus, unspecified
0.000 0.870 0.130
E32.8 Other diseases of thymus
0.000 0.870 0.130
E32.1 Abscess of thymus
0.000 0.870 0.130
E32.0 Persistent hyperplasia of thymus
0.000 0.870 0.130
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.870 0.130
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.870 0.130
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.870 0.130
E56.1 Deficiency of vitamin K
0.000 0.872 0.128
E51.9 Thiamine deficiency, unspecified
0.000 0.872 0.127
E51.8 Other manifestations of thiamine deficiency
0.000 0.872 0.127
E51.1 Beriberi
0.000 0.872 0.127
E28.3 Primary ovarian failure
0.000 0.873 0.127
E27 Other disorders of adrenal gland
0.000 0.876 0.124
E53.9 Vitamin B deficiency, unspecified
0.000 0.877 0.123
E06.5 Other chronic thyroiditis
0.000 0.877 0.122
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.878 0.121
E22.8 Other hyperfunction of pituitary gland
0.000 0.878 0.121
E56.9 Vitamin deficiency, unspecified
0.000 0.878 0.121
E56.8 Deficiency of other vitamins
0.000 0.878 0.121
E56.0 Deficiency of vitamin E
0.000 0.878 0.121
E31.9 Polyglandular dysfunction, unspecified
0.000 0.881 0.119
E31.8 Other polyglandular dysfunction
0.000 0.881 0.119
E31.1 Polyglandular hyperfunction
0.000 0.881 0.119
E67 Other hyperalimentation
0.000 0.882 0.118
E68 Sequelae of hyperalimentation
0.000 0.882 0.118
E50.9 Vitamin A deficiency, unspecified
0.000 0.883 0.117
E50.8 Other manifestations of vitamin A deficiency
0.000 0.883 0.117
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.883 0.117
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.883 0.117
E50.5 Vitamin A deficiency with night blindness
0.000 0.883 0.117
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.883 0.117
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.883 0.117
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.883 0.117
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.883 0.117
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.883 0.117
E63.9 Nutritional deficiency, unspecified
0.000 0.883 0.117
E63.8 Other specified nutritional deficiencies
0.000 0.883 0.117
E63.1 Imbalance of constituents of food intake
0.000 0.883 0.117
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.883 0.117
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.883 0.117
E64.8 Sequelae of other nutritional deficiencies
0.000 0.883 0.117
E64.3 Sequelae of rickets
0.000 0.883 0.117
E64.2 Sequelae of vitamin C deficiency
0.000 0.883 0.117
E64.1 Sequelae of vitamin A deficiency
0.000 0.883 0.117
E64.0 Sequelae of protein-energy malnutrition
0.000 0.883 0.117
E28.9 Ovarian dysfunction, unspecified
0.000 0.884 0.116
E28.8 Other ovarian dysfunction
0.000 0.884 0.116
E28.1 Androgen excess
0.000 0.884 0.116
E28.0 Oestrogen excess
0.000 0.884 0.116
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.884 0.116
E22.1 Hyperprolactinaemia
0.000 0.887 0.113
E61 Deficiency of other nutrient elements
0.000 0.888 0.111
E04.0 Non-toxic diffuse goitre
0.000 0.889 0.110
E34.5 Androgen resistance syndrome
0.000 0.895 0.105
E34.4 Constitutional tall stature
0.000 0.895 0.105
E34.3 Short stature, not elsewhere classified
0.000 0.895 0.105
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.895 0.105
E34.1 Other hypersecretion of intestinal hormones
0.000 0.895 0.105
E26.9 Hyperaldosteronism, unspecified
0.000 0.896 0.104
E26.8 Other hyperaldosteronism
0.000 0.896 0.104
E26.1 Secondary hyperaldosteronism
0.000 0.896 0.104
E53.1 Pyridoxine deficiency
0.000 0.896 0.103
E53.0 Riboflavin deficiency
0.000 0.896 0.103
E34.8 Other specified endocrine disorders
0.000 0.896 0.103
E31.0 Autoimmune polyglandular failure
0.000 0.897 0.102
E27.1 Primary adrenocortical insufficiency
0.000 0.898 0.102
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.898 0.102
E34.9 Endocrine disorder, unspecified
0.000 0.899 0.101
E55.0 Rickets, active
0.000 0.902 0.098
E65 Localised adiposity
0.000 0.908 0.092
E21.3 Hyperparathyroidism, unspecified
0.000 0.911 0.089
E27.5 Adrenomedullary hyperfunction
0.000 0.911 0.089
E27.0 Other adrenocortical overactivity
0.000 0.911 0.089
E27.8 Other specified disorders of adrenal gland
0.000 0.912 0.088
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.915 0.085
E67.8 Other specified hyperalimentation
0.000 0.915 0.085
E67.3 Hypervitaminosis D
0.000 0.915 0.085
E67.2 Megavitamin-B6 syndrome
0.000 0.915 0.085
E67.1 Hypercarotenaemia
0.000 0.915 0.085
E67.0 Hypervitaminosis A
0.000 0.915 0.085
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.917 0.083
E21.4 Other specified disorders of parathyroid gland
0.000 0.917 0.083
E21.2 Other hyperparathyroidism
0.000 0.917 0.083
E61.9 Deficiency of nutrient element, unspecified
0.000 0.920 0.080
E61.8 Deficiency of other specified nutrient elements
0.000 0.920 0.080
E61.7 Deficiency of multiple nutrient elements
0.000 0.920 0.080
E61.6 Vanadium deficiency
0.000 0.920 0.080
E61.5 Molybdenum deficiency
0.000 0.920 0.080
E61.4 Chromium deficiency
0.000 0.920 0.080
E61.3 Manganese deficiency
0.000 0.920 0.080
E61.0 Copper deficiency
0.000 0.920 0.080
E27.9 Disorder of adrenal gland, unspecified
0.000 0.920 0.080
E34.0 Carcinoid syndrome
0.000 0.922 0.078
E28.2 Polycystic ovarian syndrome
0.000 0.924 0.076
E55.9 Vitamin D deficiency, unspecified
0.000 0.928 0.072
K50-K52 Noninfective enteritis and colitis
0.071 0.929 0.000
E83.5 Disorders of calcium metabolism
0.070 0.930 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.930 0.070
E06.3 Autoimmune thyroiditis
0.000 0.930 0.069
E61.2 Magnesium deficiency
0.000 0.931 0.069
E26.0 Primary hyperaldosteronism
0.001 0.933 0.067
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.933 0.067
E11.3 With ophthalmic complications
0.000 0.934 0.066
E27.2 Addisonian crisis
0.000 0.935 0.065
K50 Crohn's disease [regional enteritis]
0.052 0.948 0.000
E61.1 Iron deficiency
0.000 0.949 0.051
K50.9 Crohn's disease, unspecified
0.046 0.954 0.000
K50.0 Crohn's disease of small intestine
0.040 0.960 0.000
K50.1 Crohn's disease of large intestine
0.033 0.967 0.000
K90-K93 Other diseases of the digestive system
0.000 0.969 0.031
E04.1 Non-toxic single thyroid nodule
0.000 0.969 0.030
E53.8 Deficiency of other specified B group vitamins
0.000 0.970 0.029
K50.8 Other Crohn's disease
0.027 0.973 0.000
E21.0 Primary hyperparathyroidism
0.000 0.977 0.023
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.977 0.022
E04.2 Non-toxic multinodular goitre
0.000 0.979 0.021
E66 Obesity
0.000 0.980 0.020
A08.4 Viral intestinal infection, unspecified
0.000 0.983 0.017
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.983 0.016
K93.1 Megacolon in Chagas' disease
0.000 0.983 0.016
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.983 0.016
E66.1 Drug-induced obesity
0.000 0.986 0.014
C43.5 Malignant melanoma of trunk
0.000 0.986 0.014
H54.0 Blindness, both eyes
0.000 0.988 0.012
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.012 0.988 0.000
E66.0 Obesity due to excess calories
0.000 0.989 0.011
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.989 0.011
E11.9 Without complications
0.000 0.989 0.011
K04.5 Chronic apical periodontitis
0.011 0.989 0.000
V18.0 Driver injured in nontraffic accident
0.010 0.990 0.000
M25.76 Osteophyte (Lower leg)
0.000 0.991 0.009
S64.0 Injury of ulnar nerve at wrist and hand level
0.008 0.991 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.992 0.008
H54 Blindness and low vision
0.000 0.992 0.008
C43 Malignant melanoma of skin
0.000 0.992 0.008
E66.8 Other obesity
0.000 0.992 0.008
T85.4 Mechanical complication of breast prosthesis and implant
0.000 0.992 0.008
C43.6 Malignant melanoma of upper limb, including shoulder
0.000 0.993 0.007
H54.9 Unspecified visual impairment (binocular)
0.000 0.993 0.007
H54.6 Unqualified visual loss, one eye
0.000 0.993 0.007
C43.3 Malignant melanoma of other and unspecified parts of face
0.000 0.993 0.007
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.993 0.007
H54.5 Low vision, one eye
0.000 0.993 0.007
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.993 0.007
H54.7 Unspecified visual loss
0.000 0.994 0.006
H54.3 Unqualified visual loss, both eyes
0.000 0.994 0.006
C43.9 Malignant melanoma of skin, unspecified
0.000 0.994 0.006
C43.4 Malignant melanoma of scalp and neck
0.000 0.994 0.006
C43.8 Overlapping malignant melanoma of skin
0.000 0.994 0.006
C43.0 Malignant melanoma of lip
0.000 0.994 0.006
S42.10 Fracture of scapula (closed)
0.000 0.994 0.006
J38.4 Oedema of larynx
0.006 0.994 0.000
I83 Varicose veins of lower extremities
0.006 0.994 0.000
J38.7 Other diseases of larynx
0.006 0.994 0.000
J38.2 Nodules of vocal cords
0.006 0.994 0.000
N18.5 Chronic kidney disease, stage 5
0.000 0.994 0.006
K52 Other non-infective gastro-enteritis and colitis
0.006 0.994 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.994 0.006
J38.3 Other diseases of vocal cords
0.006 0.994 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.006 0.994 0.000
J81 Pulmonary oedema
0.000 0.994 0.006
A08 Viral and other specified intestinal infections
0.000 0.994 0.006
C43.1 Malignant melanoma of eyelid, including canthus
0.000 0.994 0.005
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.005 0.995 0.000
Z99.1 Dependence on respirator
0.000 0.995 0.005
H54.1 Blindness, one eye, low vision, other eye
0.000 0.995 0.005
H54.2 Low vision, both eyes
0.000 0.995 0.005
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.005 0.995 0.000
H54.4 Blindness, one eye
0.000 0.995 0.005
V18 Pedal cyclist injured in noncollision transport accident
0.005 0.995 0.000
F45.8 Other somatoform disorders
0.000 0.995 0.005
N08.8 Glomerular disorders in other diseases classified elsewhere
0.000 0.995 0.005
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.000 0.995 0.005
N08.1 Glomerular disorders in neoplastic diseases
0.000 0.995 0.005
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.000 0.995 0.005
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.000 0.995 0.005
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.000 0.995 0.005
I83.1 Varicose veins of lower extremities with inflammation
0.005 0.995 0.000
J38.5 Laryngeal spasm
0.005 0.995 0.000
A08.3 Other viral enteritis
0.000 0.995 0.005
H53.2 Diplopia
0.000 0.995 0.005
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.000 0.995 0.005
M25.71 Osteophyte (Shoulder region)
0.000 0.995 0.005
N60.2 Fibroadenosis of breast
0.005 0.995 0.000
K14.8 Other diseases of tongue
0.000 0.996 0.004
E70-E90 Metabolic disorders
0.001 0.996 0.003
C43.7 Malignant melanoma of lower limb, including hip
0.000 0.996 0.004
N18.4 Chronic kidney disease, stage 4
0.000 0.996 0.004
C43.2 Malignant melanoma of ear and external auricular canal
0.000 0.996 0.004
A08.5 Other specified intestinal infections
0.000 0.996 0.004
A08.2 Adenoviral enteritis
0.000 0.996 0.004
A08.0 Rotaviral enteritis
0.000 0.996 0.004
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.004 0.996 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.004 0.996 0.000
S64 Injury of nerves at wrist and hand level
0.004 0.996 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.000 0.996 0.004
L43.9 Lichen planus, unspecified
0.000 0.996 0.004
R01.1 Cardiac murmur, unspecified
0.000 0.996 0.004
V18.5 Passenger injured in traffic accident
0.004 0.996 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.000 0.996 0.004
V18.9 Unspecified pedal cyclist injured in traffic accident
0.004 0.996 0.000
V18.4 Driver injured in traffic accident
0.004 0.996 0.000
X41.9 Unspecified place
0.004 0.996 0.000
M25.7 Osteophyte
0.000 0.996 0.004
S64.2 Injury of radial nerve at wrist and hand level
0.004 0.996 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.004 0.996 0.000
E73 Lactose intolerance
0.001 0.996 0.003
V18.1 Passenger injured in nontraffic accident
0.004 0.996 0.000
V18.3 Person injured while boarding or alighting
0.004 0.996 0.000
S64.1 Injury of median nerve at wrist and hand level
0.004 0.996 0.000
E79 Disorders of purine and pyrimidine metabolism
0.001 0.996 0.003
I83.0 Varicose veins of lower extremities with ulcer
0.004 0.996 0.000
J35.8 Other chronic diseases of tonsils and adenoids
0.004 0.996 0.000
L53.9 Erythematous condition, unspecified
0.004 0.996 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.996 0.003
N18.0 End-stage renal disease
0.000 0.996 0.004
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.003 0.996 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.000 0.996 0.003
J38.1 Polyp of vocal cord and larynx
0.003 0.996 0.000
E73.9 Lactose intolerance, unspecified
0.000 0.997 0.003
M62.8 Other specified disorders of muscle
0.000 0.997 0.003
E77 Disorders of glycoprotein metabolism
0.001 0.997 0.003
E76 Disorders of glycosaminoglycan metabolism
0.001 0.997 0.003
E72 Other disorders of amino-acid metabolism
0.001 0.997 0.003
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.997 0.003
E70 Disorders of aromatic amino-acid metabolism
0.001 0.997 0.003
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.997 0.003
E74 Other disorders of carbohydrate metabolism
0.001 0.997 0.003
S62.3 Fracture of other metacarpal bone
0.000 0.997 0.003
N18 Chronic renal failure
0.000 0.997 0.003
E84 Cystic fibrosis
0.001 0.997 0.003
K52.1 Toxic gastro-enteritis and colitis
0.003 0.997 0.000
S64.9 Injury of unspecified nerve at wrist and hand level
0.003 0.997 0.000
S64.8 Injury of other nerves at wrist and hand level
0.003 0.997 0.000
M25.79 Osteophyte (Site unspecified)
0.000 0.997 0.003
H53-H54 Visual disturbances and blindness
0.000 0.997 0.003
S42.1 Fracture of scapula
0.000 0.997 0.003
Z99.8 Dependence on other enabling machines and devices
0.000 0.997 0.003
K92.1 Melaena
0.003 0.997 0.000
J38.6 Stenosis of larynx
0.003 0.997 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.997 0.003
O43.8 Other placental disorders
0.000 0.997 0.003
K52.3 Indeterminate colitis
0.003 0.997 0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity
0.003 0.997 0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity
0.003 0.997 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.997 0.003
S64.4 Injury of digital nerve of other finger
0.003 0.997 0.000
M25.70 Osteophyte (Multiple sites)
0.000 0.997 0.003
S64.7 Injury of multiple nerves at wrist and hand level
0.003 0.997 0.000
Q23.1 Congenital insufficiency of aortic valve
0.003 0.997 0.000
M25.72 Osteophyte (Upper arm)
0.000 0.997 0.003
E73.8 Other lactose intolerance
0.001 0.997 0.002
E73.1 Secondary lactase deficiency
0.001 0.997 0.002
E73.0 Congenital lactase deficiency
0.001 0.997 0.002
S62.31 Fracture of other metacarpal bone (open)
0.000 0.997 0.003
E75.5 Other lipid storage disorders
0.001 0.997 0.002
N85.1 Endometrial adenomatous hyperplasia
0.000 0.997 0.003
Q23.0 Congenital stenosis of aortic valve
0.003 0.997 0.000
R01.0 Benign and innocent cardiac murmurs
0.000 0.997 0.003
Q23 Congenital malformations of aortic and mitral valves
0.003 0.997 0.000
M25.73 Osteophyte (Forearm)
0.000 0.997 0.003
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.000 0.997 0.003
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.997 0.002
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.997 0.002
E79.1 Lesch-Nyhan syndrome
0.001 0.997 0.002
M25.75 Osteophyte (Pelvic region and thigh)
0.000 0.997 0.003
E85 Amyloidosis
0.001 0.997 0.002
M62.83 Other specified disorders of muscle (Forearm)
0.000 0.997 0.003
D47.2 Monoclonal gammopathy
0.000 0.997 0.003
E75.6 Lipid storage disorder, unspecified
0.001 0.997 0.002
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.997 0.002
E75.3 Sphingolipidosis, unspecified
0.001 0.997 0.002
E75.2 Other sphingolipidosis
0.001 0.997 0.002
E75.1 Other gangliosidosis
0.001 0.997 0.002
E75.0 GM2 gangliosidosis
0.001 0.997 0.002
M62.88 Other specified disorders of muscle (Other)
0.000 0.997 0.003
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.997 0.003
D47.4 Osteomyelofibrosis
0.000 0.997 0.003
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.997 0.003
R01 Cardiac murmurs and other cardiac sounds
0.000 0.997 0.003
M62.87 Other specified disorders of muscle (Ankle and foot)
0.000 0.997 0.003
M62.86 Other specified disorders of muscle (Lower leg)
0.000 0.997 0.003
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.997 0.002
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.997 0.002
E70.3 Albinism
0.001 0.997 0.002
E70.2 Disorders of tyrosine metabolism
0.001 0.997 0.002
E70.1 Other hyperphenylalaninaemias
0.001 0.997 0.002
E70.0 Classical phenylketonuria
0.001 0.997 0.002
E71.3 Disorders of fatty-acid metabolism
0.001 0.997 0.002
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.997 0.002
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.997 0.002
E71.0 Maple-syrup-urine disease
0.001 0.997 0.002
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.997 0.002
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.997 0.002
E72.5 Disorders of glycine metabolism
0.001 0.997 0.002
E72.4 Disorders of ornithine metabolism
0.001 0.997 0.002
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.997 0.002
E72.2 Disorders of urea cycle metabolism
0.001 0.997 0.002
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.997 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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