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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2394660
log Bayes Factor = 36.24
Chromosome 6   position 29,672,686  (GRCh37) Explore rs2394660 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.002 0.998
L40 Psoriasis
0.000 0.006 0.994
L40.5 Arthropathic psoriasis
0.000 0.007 0.993
E10.1 With ketoacidosis
0.000 0.011 0.989
E10.3 With ophthalmic complications
0.000 0.028 0.972
E10.0 With coma
0.000 0.122 0.878
G35 Multiple sclerosis
0.870 0.130 0.000
L40.8 Other psoriasis
0.000 0.205 0.795
E10.2 With renal complications
0.000 0.216 0.784
L40.0 Psoriasis vulgaris
0.000 0.240 0.760
E10.6 With other specified complications
0.000 0.274 0.726
L40.2 Acrodermatitis continua
0.000 0.287 0.713
L40.1 Generalised pustular psoriasis
0.000 0.287 0.713
E10.8 With unspecified complications
0.000 0.323 0.676
E10.7 With multiple complications
0.000 0.332 0.667
L40.3 Pustulosis palmaris et plantaris
0.000 0.360 0.640
L40.4 Guttate psoriasis
0.000 0.361 0.639
E10.4 With neurological complications
0.000 0.369 0.631
E10.5 With peripheral circulatory complications
0.000 0.380 0.620
K90 Intestinal malabsorption
0.000 0.502 0.498
G35-G37 Demyelinating diseases of the central nervous system
0.474 0.526 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.588 0.412
G37 Other demyelinating diseases of central nervous system
0.384 0.616 0.000
K90.8 Other intestinal malabsorption
0.000 0.634 0.366
K90.3 Pancreatic steatorrhoea
0.000 0.643 0.357
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.643 0.357
K90.1 Tropical sprue
0.000 0.643 0.357
G36 Other acute disseminated demyelination
0.354 0.646 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.336 0.664 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.695 0.305
G37.8 Other specified demyelinating diseases of central nervous system
0.281 0.719 0.000
G37.5 Concentric sclerosis [Balo]
0.275 0.725 0.000
G37.4 Subacute necrotising myelitis
0.275 0.725 0.000
G37.2 Central pontine myelinolysis
0.275 0.725 0.000
G37.1 Central demyelination of corpus callosum
0.275 0.725 0.000
G37.0 Diffuse sclerosis
0.275 0.725 0.000
E83 Disorders of mineral metabolism
0.270 0.730 0.000
G36.0 Neuromyelitis optica [Devic]
0.268 0.731 0.000
G36.9 Acute disseminated demyelination, unspecified
0.254 0.746 0.000
G36.8 Other specified acute disseminated demyelination
0.254 0.746 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.254 0.746 0.000
E10-E14 Diabetes mellitus
0.000 0.746 0.254
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.247 0.753 0.000
E83.3 Disorders of phosphorus metabolism
0.239 0.761 0.000
L40-L45 Papulosquamous disorders
0.013 0.761 0.225
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.229 0.771 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.779 0.221
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.783 0.217
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.785 0.215
I71 Aortic aneurysm and dissection
0.211 0.789 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.804 0.196
E14 Unspecified diabetes mellitus
0.000 0.804 0.196
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.805 0.195
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.805 0.195
I71.3 Abdominal aortic aneurysm, ruptured
0.195 0.805 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.194 0.806 0.000
E83.8 Other disorders of mineral metabolism
0.194 0.806 0.000
E83.2 Disorders of zinc metabolism
0.194 0.806 0.000
E83.0 Disorders of copper metabolism
0.194 0.806 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.813 0.187
I71.0 Dissection of aorta [any part]
0.185 0.815 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.817 0.182
L44 Other papulosquamous disorders
0.010 0.829 0.162
L41 Parapsoriasis
0.010 0.829 0.162
L45 Papulosquamous disorders in diseases classified elsewhere
0.010 0.829 0.162
E13 Other specified diabetes mellitus
0.000 0.831 0.169
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.831 0.169
L42 Pityriasis rosea
0.009 0.833 0.158
E14.3 With ophthalmic complications
0.000 0.836 0.164
I71.1 Thoracic aortic aneurysm, ruptured
0.162 0.838 0.000
E14.4 With neurological complications
0.000 0.840 0.159
E14.5 With peripheral circulatory complications
0.000 0.842 0.158
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.156 0.844 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.151 0.848 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.151 0.848 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.145 0.855 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.857 0.143
E14.1 With ketoacidosis
0.000 0.857 0.143
E14.7 With multiple complications
0.000 0.859 0.141
E14.2 Withrenal complications
0.000 0.859 0.141
E14.0 With coma
0.000 0.859 0.141
E14.8 With unspecified complications
0.000 0.860 0.140
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.133 0.867 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.868 0.132
E12.9 Without complications
0.000 0.869 0.131
E12.8 With unspecified complications
0.000 0.869 0.131
E12.7 With multiple complications
0.000 0.869 0.131
E12.6 With other specified complications
0.000 0.869 0.131
E12.5 With peripheral circulatory complications
0.000 0.869 0.131
E12.4 With neurological complications
0.000 0.869 0.131
E12.3 With ophthalmic complications
0.000 0.869 0.131
E12.2 With renal complications
0.000 0.869 0.131
E12.1 With ketoacidosis
0.000 0.869 0.131
E12.0 With coma
0.000 0.869 0.131
E14.6 With other specified complications
0.000 0.869 0.131
E13.3 With ophthalmic complications
0.000 0.876 0.124
L41.9 Parapsoriasis, unspecified
0.007 0.877 0.116
L41.8 Other parapsoriasis
0.007 0.877 0.116
L41.5 Retiform parapsoriasis
0.007 0.877 0.116
L41.4 Large plaque parapsoriasis
0.007 0.877 0.116
L41.3 Small plaque parapsoriasis
0.007 0.877 0.116
L41.2 Lymphomatoid papulosis
0.007 0.877 0.116
L41.1 Pityriasis lichenoides chronica
0.007 0.877 0.116
L41.0 Pityriasis lichenoides et varioliformis acuta
0.007 0.877 0.116
L44.9 Papulosquamous disorder, unspecified
0.007 0.877 0.116
L44.8 Other specified papulosquamous disorders
0.007 0.877 0.116
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.007 0.877 0.116
L44.3 Lichen ruber moniliformis
0.007 0.877 0.116
L44.2 Lichen striatus
0.007 0.877 0.116
L44.1 Lichen nitidus
0.007 0.877 0.116
L44.0 Pityriasis rubra pilaris
0.007 0.877 0.116
E13.8 With unspecified complications
0.000 0.879 0.121
E13.7 With multiple complications
0.000 0.879 0.121
E13.6 With other specified complications
0.000 0.879 0.121
E13.5 With peripheral circulatory complications
0.000 0.879 0.121
E13.4 With neurological complications
0.000 0.879 0.121
E13.2 With renal complications
0.000 0.879 0.121
E13.1 With ketoacidosis
0.000 0.879 0.121
E13.0 With coma
0.000 0.879 0.121
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.884 0.115
L43 Lichen planus
0.042 0.888 0.070
E13.9 Without complications
0.000 0.895 0.104
M06 Other rheumatoid arthritis
0.000 0.896 0.104
E83.5 Disorders of calcium metabolism
0.098 0.902 0.000
E83.4 Disorders of magnesium metabolism
0.084 0.916 0.000
M06.3 Rheumatoid nodule
0.000 0.919 0.081
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.000 0.919 0.081
N13.5 Kinking and stricture of ureter without hydronephrosis
0.000 0.919 0.081
L43.3 Subacute (active) lichen planus
0.030 0.919 0.050
L43.2 Lichenoid drug reaction
0.030 0.919 0.050
L43.1 Bullous lichen planus
0.030 0.919 0.050
L43.0 Hypertrophic lichen planus
0.030 0.919 0.050
N13 Obstructive and reflux uropathy
0.000 0.920 0.080
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.000 0.922 0.078
M06.8 Other specified rheumatoid arthritis
0.000 0.925 0.075
M06.2 Rheumatoid bursitis
0.000 0.925 0.075
M06.1 Adult-onset Still's disease
0.000 0.925 0.075
L43.8 Other lichen planus
0.033 0.928 0.038
M06.4 Inflammatory polyarthropathy
0.000 0.930 0.070
L43.9 Lichen planus, unspecified
0.069 0.930 0.002
N13.9 Obstructive and reflux uropathy, unspecified
0.000 0.931 0.069
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.931 0.069
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.000 0.936 0.064
N13.7 Vesicoureteral-reflux-associated uropathy
0.000 0.936 0.064
Chapter IV Endocrine, nutritional and metabolic diseases
0.003 0.938 0.059
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.940 0.060
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.940 0.060
E14.9 Without complications
0.000 0.940 0.060
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.001 0.941 0.058
E89.0 Postprocedural hypothyroidism
0.059 0.941 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.941 0.058
M06.38 Rheumatoid nodule (Other)
0.000 0.941 0.058
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.941 0.058
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.941 0.058
M06.33 Rheumatoid nodule (Forearm)
0.000 0.941 0.058
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.941 0.058
E21.3 Hyperparathyroidism, unspecified
0.000 0.942 0.058
E16 Other disorders of pancreatic internal secretion
0.000 0.943 0.057
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.055 0.944 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.946 0.054
E16.2 Hypoglycaemia, unspecified
0.000 0.946 0.054
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.946 0.054
M06.18 Adult-onset Still's disease (Other)
0.000 0.946 0.054
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.946 0.054
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.946 0.054
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.946 0.054
M06.14 Adult-onset Still's disease (Hand)
0.000 0.946 0.054
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.946 0.054
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.946 0.054
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.946 0.054
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.946 0.054
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.946 0.054
M06.28 Rheumatoid bursitis (Other)
0.000 0.946 0.054
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.946 0.054
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.946 0.054
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.946 0.054
M06.24 Rheumatoid bursitis (Hand)
0.000 0.946 0.054
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.946 0.054
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.946 0.054
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.946 0.054
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.946 0.054
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.946 0.054
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.946 0.054
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.946 0.054
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.946 0.054
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.946 0.054
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.946 0.054
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.946 0.054
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.946 0.054
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.946 0.054
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.946 0.054
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.946 0.054
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.948 0.052
M07.3 Other psoriatic arthropathies
0.000 0.948 0.052
M06.0 Seronegative rheumatoid arthritis
0.000 0.948 0.052
M05-M14 Inflammatory polyarthropathies
0.000 0.949 0.051
M07 Psoriatic and enteropathic arthropathies
0.000 0.949 0.051
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.949 0.050
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.949 0.050
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.949 0.050
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.949 0.050
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.949 0.050
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.949 0.050
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.949 0.050
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.949 0.050
E50-E64 Other nutritional deficiencies
0.001 0.950 0.049
E20-E35 Disorders of other endocrine glands
0.000 0.950 0.050
E89.2 Postprocedural hypoparathyroidism
0.050 0.950 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.049 0.951 0.000
E61 Deficiency of other nutrient elements
0.000 0.951 0.048
M06.34 Rheumatoid nodule (Hand)
0.000 0.951 0.049
E11 Non-insulin-dependent diabetes mellitus
0.000 0.951 0.049
N13.3 Other and unspecified hydronephrosis
0.000 0.951 0.049
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.952 0.048
N13.6 Pyonephrosis
0.000 0.952 0.048
E16.1 Other hypoglycaemia
0.000 0.952 0.048
E61.1 Iron deficiency
0.000 0.952 0.048
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.955 0.045
E70-E90 Metabolic disorders
0.043 0.955 0.002
E89.4 Postprocedural ovarian failure
0.044 0.955 0.000
E89.1 Postprocedural hypoinsulinaemia
0.043 0.957 0.000
E24 Cushing's syndrome
0.000 0.957 0.043
E11.0 With coma
0.000 0.957 0.043
E15 Nondiabetic hypoglycaemic coma
0.001 0.957 0.041
M12 Other specific arthropathies
0.000 0.958 0.042
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.959 0.041
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.959 0.041
E16.4 Abnormal secretion of gastrin
0.000 0.959 0.041
E16.3 Increased secretion of glucagon
0.000 0.959 0.041
E11.6 With other specified complications
0.000 0.959 0.041
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.959 0.041
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.960 0.040
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.040 0.960 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.040 0.960 0.000
E89.5 Postprocedural testicular hypofunction
0.040 0.960 0.000
E21.0 Primary hyperparathyroidism
0.000 0.960 0.040
E28 Ovarian dysfunction
0.000 0.961 0.039
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.961 0.039
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.961 0.039
K90-K93 Other diseases of the digestive system
0.000 0.961 0.039
E61.2 Magnesium deficiency
0.000 0.962 0.038
E21.4 Other specified disorders of parathyroid gland
0.000 0.962 0.038
M07.38 Other psoriatic arthropathies (Other)
0.000 0.962 0.037
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.962 0.037
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.962 0.037
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.962 0.037
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.963 0.037
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.963 0.037
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.963 0.037
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.963 0.037
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.963 0.037
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.963 0.037
M11 Other crystal arthropathies
0.000 0.963 0.037
E29 Testicular dysfunction
0.000 0.963 0.037
E11.8 With unspecified complications
0.000 0.963 0.037
M07.5 Arthropathy in ulcerative colitis
0.000 0.963 0.037
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.963 0.037
M07.2 Psoriatic spondylitis
0.000 0.963 0.037
M07.1 Arthritis mutilans
0.000 0.963 0.037
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.963 0.037
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.963 0.037
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.963 0.036
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.964 0.035
E63 Other nutritional deficiencies
0.001 0.964 0.035
E56 Other vitamin deficiencies
0.001 0.964 0.035
E50 Vitamin A deficiency
0.001 0.964 0.035
E60 Dietary zinc deficiency
0.001 0.964 0.035
E59 Dietary selenium deficiency
0.001 0.964 0.035
E54 Ascorbic acid deficiency
0.001 0.964 0.035
E52 Niacin deficiency [pellagra]
0.001 0.964 0.035
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.964 0.036
E32 Diseases of thymus
0.000 0.964 0.036
E31 Polyglandular dysfunction
0.000 0.964 0.036
E30 Disorders of puberty, not elsewhere classified
0.000 0.964 0.036
M07.6 Other enteropathic arthropathies
0.000 0.964 0.036
E51 Thiamine deficiency
0.001 0.964 0.035
M08 Juvenile arthritis
0.000 0.964 0.035
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.965 0.035
C73 Malignant neoplasm of thyroid gland
0.035 0.965 0.000
E25 Adrenogenital disorders
0.000 0.965 0.035
E61.9 Deficiency of nutrient element, unspecified
0.000 0.965 0.035
E61.8 Deficiency of other specified nutrient elements
0.000 0.965 0.035
E61.7 Deficiency of multiple nutrient elements
0.000 0.965 0.035
E61.6 Vanadium deficiency
0.000 0.965 0.035
E61.5 Molybdenum deficiency
0.000 0.965 0.035
E61.4 Chromium deficiency
0.000 0.965 0.035
E61.3 Manganese deficiency
0.000 0.965 0.035
E61.0 Copper deficiency
0.000 0.965 0.035
E11.7 With multiple complications
0.000 0.965 0.035
E24.2 Drug-induced Cushing's syndrome
0.000 0.965 0.035
E24.0 Pituitary-dependent Cushing's disease
0.000 0.965 0.035
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.966 0.034
E84 Cystic fibrosis
0.033 0.966 0.001
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.966 0.034
E28.2 Polycystic ovarian syndrome
0.000 0.966 0.034
E21.2 Other hyperparathyroidism
0.000 0.966 0.034
E40-E46 Malnutrition
0.002 0.966 0.031
M12.3 Palindromic rheumatism
0.000 0.967 0.033
E74 Other disorders of carbohydrate metabolism
0.032 0.967 0.001
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.032 0.967 0.001
N13.8 Other obstructive and reflux uropathy
0.000 0.967 0.033
M14 Arthropathies in other diseases classified elsewhere
0.000 0.967 0.033
M12.2 Villonodular synovitis (pigmented)
0.000 0.967 0.032
E77 Disorders of glycoprotein metabolism
0.031 0.968 0.001
E76 Disorders of glycosaminoglycan metabolism
0.031 0.968 0.001
E72 Other disorders of amino-acid metabolism
0.031 0.968 0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.031 0.968 0.001
E70 Disorders of aromatic amino-acid metabolism
0.031 0.968 0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.031 0.968 0.001
E58 Dietary calcium deficiency
0.001 0.968 0.031
E11.2 With renal complications
0.000 0.968 0.032
E24.9 Cushing's syndrome, unspecified
0.000 0.969 0.031
E55 Vitamin D deficiency
0.001 0.969 0.031
E20 Hypoparathyroidism
0.000 0.969 0.031
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.969 0.031
E24.8 Other Cushing's syndrome
0.000 0.969 0.031
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.969 0.031
E24.3 Ectopic ACTH syndrome
0.000 0.969 0.031
E24.1 Nelson's syndrome
0.000 0.969 0.031
N13.4 Hydroureter
0.000 0.970 0.030
E11.1 With ketoacidosis
0.000 0.970 0.030
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.970 0.030
M12.5 Traumatic arthropathy
0.000 0.970 0.030
M12.4 Intermittent hydrarthrosis
0.000 0.970 0.030
M12.1 Kaschin-Beck disease
0.000 0.970 0.030
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.970 0.030
E79 Disorders of purine and pyrimidine metabolism
0.029 0.970 0.001
E34 Other endocrine disorders
0.000 0.970 0.030
N10-N16 Renal tubulo-interstitial diseases
0.000 0.970 0.030
M13 Other arthritis
0.000 0.971 0.029
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.971 0.028
E23 Hypofunction and other disorders of pituitary gland
0.000 0.971 0.029
E28.9 Ovarian dysfunction, unspecified
0.000 0.971 0.028
E28.8 Other ovarian dysfunction
0.000 0.971 0.028
E28.1 Androgen excess
0.000 0.971 0.028
E28.0 Oestrogen excess
0.000 0.971 0.028
N11 Chronic tubulo-interstitial nephritis
0.000 0.972 0.028
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.972 0.028
E73 Lactose intolerance
0.027 0.972 0.001
M11.2 Other chondrocalcinosis
0.000 0.972 0.028
E29.1 Testicular hypofunction
0.000 0.972 0.028
N11.9 Chronic tubulo-interstitial nephritis, unspecified
0.000 0.973 0.027
M11.1 Familial chondrocalcinosis
0.000 0.973 0.027
M11.0 Hydroxyapatite deposition disease
0.000 0.973 0.027
M12.26 Villonodular synovitis (pigmented) (Lower leg)
0.000 0.973 0.027
E29.9 Testicular dysfunction, unspecified
0.000 0.973 0.027
E29.8 Other testicular dysfunction
0.000 0.973 0.027
E29.0 Testicular hyperfunction
0.000 0.973 0.027
E22 Hyperfunction of pituitary gland
0.000 0.973 0.027
E84.9 Cystic fibrosis, unspecified
0.026 0.973 0.001
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.973 0.027
E11.4 With neurological complications
0.000 0.973 0.027
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.973 0.026
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.973 0.026
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.973 0.026
M09.0 Juvenile arthritis in psoriasis
0.000 0.973 0.026
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.000 0.973 0.026
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.000 0.973 0.026
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.000 0.973 0.026
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.000 0.973 0.026
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.000 0.973 0.026
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.000 0.973 0.026
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.000 0.973 0.026
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.000 0.973 0.026
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.000 0.973 0.026
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.000 0.973 0.026
M07.19 Arthritis mutilans (Site unspecified)
0.000 0.973 0.026
M07.18 Arthritis mutilans (Other)
0.000 0.973 0.026
M07.17 Arthritis mutilans (Ankle and foot)
0.000 0.973 0.026
M07.16 Arthritis mutilans (Lower leg)
0.000 0.973 0.026
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.000 0.973 0.026
M07.14 Arthritis mutilans (Hand)
0.000 0.973 0.026
M07.13 Arthritis mutilans (Forearm)
0.000 0.973 0.026
M07.12 Arthritis mutilans (Upper arm)
0.000 0.973 0.026
M07.11 Arthritis mutilans (Shoulder region)
0.000 0.973 0.026
M07.10 Arthritis mutilans (Multiple sites)
0.000 0.973 0.026
M07.29 Psoriatic spondylitis (Site unspecified)
0.000 0.973 0.026
M07.28 Psoriatic spondylitis (Other)
0.000 0.973 0.026
M07.27 Psoriatic spondylitis (Ankle and foot)
0.000 0.973 0.026
M07.26 Psoriatic spondylitis (Lower leg)
0.000 0.973 0.026
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.000 0.973 0.026
M07.24 Psoriatic spondylitis (Hand)
0.000 0.973 0.026
M07.23 Psoriatic spondylitis (Forearm)
0.000 0.973 0.026
M07.22 Psoriatic spondylitis (Upper arm)
0.000 0.973 0.026
M07.21 Psoriatic spondylitis (Shoulder region)
0.000 0.973 0.026
M07.20 Psoriatic spondylitis (Multiple sites)
0.000 0.973 0.026
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.000 0.973 0.026
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.000 0.973 0.026
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.000 0.973 0.026
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.000 0.973 0.026
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.000 0.973 0.026
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.000 0.973 0.026
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.000 0.973 0.026
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.000 0.973 0.026
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.000 0.973 0.026
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.000 0.973 0.026
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.000 0.973 0.026
M07.58 Arthropathy in ulcerative colitis (Other)
0.000 0.973 0.026
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.000 0.973 0.026
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.000 0.973 0.026
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.000 0.973 0.026
M07.54 Arthropathy in ulcerative colitis (Hand)
0.000 0.973 0.026
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.000 0.973 0.026
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.000 0.973 0.026
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.000 0.973 0.026
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.000 0.973 0.026
M11.9 Crystal arthropathy, unspecified
0.000 0.973 0.026
M11.8 Other specified crystal arthropathies
0.000 0.973 0.026
E50.9 Vitamin A deficiency, unspecified
0.001 0.974 0.026
E50.8 Other manifestations of vitamin A deficiency
0.001 0.974 0.026
E50.7 Other ocular manifestations of vitamin A deficiency
0.001 0.974 0.026
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.001 0.974 0.026
E50.5 Vitamin A deficiency with night blindness
0.001 0.974 0.026
E50.4 Vitamin A deficiency with keratomalacia
0.001 0.974 0.026
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.001 0.974 0.026
E50.2 Vitamin A deficiency with corneal xerosis
0.001 0.974 0.026
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.001 0.974 0.026
E50.0 Vitamin A deficiency with conjunctival xerosis
0.001 0.974 0.026
E56.9 Vitamin deficiency, unspecified
0.001 0.974 0.026
E56.8 Deficiency of other vitamins
0.001 0.974 0.026
E56.1 Deficiency of vitamin K
0.001 0.974 0.026
E56.0 Deficiency of vitamin E
0.001 0.974 0.026
E63.9 Nutritional deficiency, unspecified
0.001 0.974 0.026
E63.8 Other specified nutritional deficiencies
0.001 0.974 0.026
E63.1 Imbalance of constituents of food intake
0.001 0.974 0.026
E63.0 Essential fatty acid [EFA] deficiency
0.001 0.974 0.026
E64.9 Sequelae of unspecified nutritional deficiency
0.001 0.974 0.026
E64.8 Sequelae of other nutritional deficiencies
0.001 0.974 0.026
E64.3 Sequelae of rickets
0.001 0.974 0.026
E64.2 Sequelae of vitamin C deficiency
0.001 0.974 0.026
E64.1 Sequelae of vitamin A deficiency
0.001 0.974 0.026
E64.0 Sequelae of protein-energy malnutrition
0.001 0.974 0.026
E30.9 Disorder of puberty, unspecified
0.000 0.974 0.026
E30.8 Other disorders of puberty
0.000 0.974 0.026
E30.1 Precocious puberty
0.000 0.974 0.026
E30.0 Delayed puberty
0.000 0.974 0.026
E31.9 Polyglandular dysfunction, unspecified
0.000 0.974 0.026
E31.8 Other polyglandular dysfunction
0.000 0.974 0.026
E31.1 Polyglandular hyperfunction
0.000 0.974 0.026
E31.0 Autoimmune polyglandular failure
0.000 0.974 0.026
E32.9 Disease of thymus, unspecified
0.000 0.974 0.026
E32.8 Other diseases of thymus
0.000 0.974 0.026
E32.1 Abscess of thymus
0.000 0.974 0.026
E32.0 Persistent hyperplasia of thymus
0.000 0.974 0.026
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.974 0.026
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.974 0.026
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.974 0.026
M07.68 Other enteropathic arthropathies (Other)
0.000 0.974 0.026
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.000 0.974 0.026
M07.66 Other enteropathic arthropathies (Lower leg)
0.000 0.974 0.026
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.000 0.974 0.026
M07.64 Other enteropathic arthropathies (Hand)
0.000 0.974 0.026
M07.63 Other enteropathic arthropathies (Forearm)
0.000 0.974 0.026
M07.62 Other enteropathic arthropathies (Upper arm)
0.000 0.974 0.026
M07.61 Other enteropathic arthropathies (Shoulder region)
0.000 0.974 0.026
M07.60 Other enteropathic arthropathies (Multiple sites)
0.000 0.974 0.026
E51.9 Thiamine deficiency, unspecified
0.001 0.974 0.025
E51.8 Other manifestations of thiamine deficiency
0.001 0.974 0.025
E51.1 Beriberi
0.001 0.974 0.025
M08.9 Juvenile arthritis, unspecified
0.000 0.974 0.026
M08.8 Other juvenile arthritis
0.000 0.974 0.026
M08.4 Pauciarticular juvenile arthritis
0.000 0.974 0.026
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.974 0.026
M08.2 Juvenile arthritis with systemic onset
0.000 0.974 0.026
M08.1 Juvenile ankylosing spondylitis
0.000 0.974 0.026
E26 Hyperaldosteronism
0.000 0.974 0.025
M07.69 Other enteropathic arthropathies (Site unspecified)
0.000 0.974 0.025
E25.9 Adrenogenital disorder, unspecified
0.000 0.974 0.025
E25.8 Other adrenogenital disorders
0.000 0.974 0.025
E51.2 Wernicke's encephalopathy
0.001 0.974 0.025
M12.30 Palindromic rheumatism (Multiple sites)
0.000 0.975 0.025
E74.3 Other disorders of intestinal carbohydrate absorption
0.025 0.975 0.001
E84.8 Cystic fibrosis with other manifestations
0.024 0.975 0.001
E84.1 Cystic fibrosis with intestinal manifestations
0.024 0.975 0.001
E84.0 Cystic fibrosis with pulmonary manifestations
0.024 0.975 0.001
E75.5 Other lipid storage disorders
0.024 0.975 0.001
E80 Disorders of porphyrin and bilirubin metabolism
0.023 0.975 0.001
M13.0 Polyarthritis, unspecified
0.000 0.975 0.025
M08.0 Juvenile rheumatoid arthritis
0.000 0.975 0.024
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.975 0.024
E44 Protein-energy malnutrition of moderate and mild degree
0.002 0.976 0.023
E45 Retarded development following protein-energy malnutrition
0.002 0.976 0.023
E43 Unspecified severe protein-energy malnutrition
0.002 0.976 0.023
E42 Marasmic kwashiorkor
0.002 0.976 0.023
E41 Nutritional marasmus
0.002 0.976 0.023
E40 Kwashiorkor
0.002 0.976 0.023
E28.3 Primary ovarian failure
0.000 0.976 0.024
M12.38 Palindromic rheumatism (Other)
0.000 0.976 0.024
M12.37 Palindromic rheumatism (Ankle and foot)
0.000 0.976 0.024
M12.36 Palindromic rheumatism (Lower leg)
0.000 0.976 0.024
M12.35 Palindromic rheumatism (Pelvic region and thigh)
0.000 0.976 0.024
M12.34 Palindromic rheumatism (Hand)
0.000 0.976 0.024
M12.33 Palindromic rheumatism (Forearm)
0.000 0.976 0.024
M12.32 Palindromic rheumatism (Upper arm)
0.000 0.976 0.024
M12.31 Palindromic rheumatism (Shoulder region)
0.000 0.976 0.024
E74.9 Disorder of carbohydrate metabolism, unspecified
0.023 0.976 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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