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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2394882
log Bayes Factor = 75.4285
Chromosome 6   position 31,132,649  (GRCh37) Explore rs2394882 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
G35 Multiple sclerosis
0.996 0.004 0.000
E14 Unspecified diabetes mellitus
0.000 0.005 0.995
M06.9 Rheumatoid arthritis, unspecified
0.000 0.005 0.995
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.006 0.994
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.028 0.972
E14.3 With ophthalmic complications
0.000 0.038 0.962
E14.9 Without complications
0.000 0.046 0.954
L40 Psoriasis
0.000 0.049 0.951
E11 Non-insulin-dependent diabetes mellitus
0.000 0.054 0.946
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.057 0.943
E10.3 With ophthalmic complications
0.000 0.057 0.943
E11.9 Without complications
0.000 0.066 0.934
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.069 0.931
K51.9 Ulcerative colitis, unspecified
0.923 0.077 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.081 0.919
K51 Ulcerative colitis
0.910 0.090 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.096 0.904
K51.2 Ulcerative (chronic) proctitis
0.890 0.110 0.000
L40.5 Arthropathic psoriasis
0.000 0.128 0.872
K51.4 Pseudopolyposis of colon
0.867 0.133 0.000
E11.1 With ketoacidosis
0.000 0.141 0.859
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.147 0.853
L40.0 Psoriasis vulgaris
0.000 0.156 0.844
K51.3 Ulcerative (chronic) rectosigmoiditis
0.837 0.163 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.819 0.181 0.000
E13 Other specified diabetes mellitus
0.000 0.183 0.817
E03 Other hypothyroidism
0.000 0.184 0.816
E00-E07 Disorders of thyroid gland
0.000 0.187 0.813
E03.9 Hypothyroidism, unspecified
0.000 0.187 0.813
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.191 0.809
L40.8 Other psoriasis
0.000 0.194 0.806
E05.9 Thyrotoxicosis, unspecified
0.000 0.198 0.802
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.200 0.800
E10.8 With unspecified complications
0.000 0.201 0.799
E10.1 With ketoacidosis
0.000 0.218 0.782
L40.1 Generalised pustular psoriasis
0.000 0.223 0.777
E10.0 With coma
0.000 0.223 0.777
E14.4 With neurological complications
0.000 0.224 0.776
E83.1 Disorders of iron metabolism
0.774 0.226 0.000
G37 Other demyelinating diseases of central nervous system
0.769 0.231 0.000
E10.6 With other specified complications
0.000 0.232 0.768
E14.5 With peripheral circulatory complications
0.000 0.234 0.766
K90 Intestinal malabsorption
0.000 0.240 0.760
E14.1 With ketoacidosis
0.000 0.240 0.759
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.243 0.756
E14.6 With other specified complications
0.000 0.262 0.738
E11.0 With coma
0.000 0.277 0.723
K51.5 Mucosal proctocolitis
0.722 0.278 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.719 0.281 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.716
E14.7 With multiple complications
0.000 0.286 0.713
E14.0 With coma
0.000 0.286 0.713
E03.8 Other specified hypothyroidism
0.000 0.287 0.713
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.289 0.711
E14.2 Withrenal complications
0.000 0.296 0.704
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.297 0.703
E13.9 Without complications
0.000 0.298 0.702
L40.4 Guttate psoriasis
0.000 0.312 0.688
L40.2 Acrodermatitis continua
0.000 0.318 0.681
E11.7 With multiple complications
0.000 0.322 0.678
K90.9 Intestinal malabsorption, unspecified
0.000 0.332 0.668
E11.4 With neurological complications
0.000 0.332 0.668
E11.5 With peripheral circulatory complications
0.000 0.342 0.658
G36 Other acute disseminated demyelination
0.647 0.353 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.645 0.355 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.358 0.642
E14.8 With unspecified complications
0.000 0.366 0.634
J45.9 Asthma, unspecified
0.000 0.371 0.629
E10.2 With renal complications
0.000 0.372 0.628
E16 Other disorders of pancreatic internal secretion
0.000 0.373 0.627
E07 Other disorders of thyroid
0.000 0.373 0.626
E10.5 With peripheral circulatory complications
0.000 0.382 0.618
L40.3 Pustulosis palmaris et plantaris
0.000 0.392 0.608
G37.8 Other specified demyelinating diseases of central nervous system
0.607 0.393 0.000
E11.2 With renal complications
0.000 0.394 0.606
E10.4 With neurological complications
0.000 0.394 0.606
E83 Disorders of mineral metabolism
0.603 0.396 0.000
E11.8 With unspecified complications
0.000 0.408 0.592
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.408 0.592
E13.8 With unspecified complications
0.000 0.414 0.586
E13.7 With multiple complications
0.000 0.414 0.586
E13.6 With other specified complications
0.000 0.414 0.586
E13.5 With peripheral circulatory complications
0.000 0.414 0.586
E13.4 With neurological complications
0.000 0.414 0.586
E13.2 With renal complications
0.000 0.414 0.586
E13.1 With ketoacidosis
0.000 0.414 0.586
E13.0 With coma
0.000 0.414 0.586
E03.5 Myxoedema coma
0.000 0.415 0.585
E03.4 Atrophy of thyroid (acquired)
0.000 0.415 0.585
E03.3 Postinfectious hypothyroidism
0.000 0.415 0.585
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.415 0.585
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.417 0.583
E00 Congenital iodine-deficiency syndrome
0.000 0.417 0.583
E05.5 Thyroid crisis or storm
0.000 0.426 0.574
E05.4 Thyrotoxicosis factitia
0.000 0.426 0.574
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.426 0.574
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.426 0.574
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.564 0.436 0.000
E13.3 With ophthalmic complications
0.000 0.445 0.555
E16.2 Hypoglycaemia, unspecified
0.000 0.446 0.554
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.447 0.553
G37.5 Concentric sclerosis [Balo]
0.552 0.448 0.000
G37.4 Subacute necrotising myelitis
0.552 0.448 0.000
G37.2 Central pontine myelinolysis
0.552 0.448 0.000
G37.1 Central demyelination of corpus callosum
0.552 0.448 0.000
G37.0 Diffuse sclerosis
0.552 0.448 0.000
J47 Bronchiectasis
0.551 0.449 0.000
E83.3 Disorders of phosphorus metabolism
0.546 0.454 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.455 0.545
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.455 0.545
K90.1 Tropical sprue
0.000 0.455 0.545
K90.8 Other intestinal malabsorption
0.000 0.470 0.529
G36.0 Neuromyelitis optica [Devic]
0.524 0.476 0.000
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E03.1 Congenital hypothyroidism without goitre
0.000 0.491 0.509
E83.4 Disorders of magnesium metabolism
0.507 0.493 0.000
E40-E46 Malnutrition
0.000 0.495 0.505
E15 Nondiabetic hypoglycaemic coma
0.000 0.496 0.504
E16.1 Other hypoglycaemia
0.000 0.507 0.493
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.522 0.478
E07.8 Other specified disorders of thyroid
0.000 0.523 0.477
E07.9 Disorder of thyroid, unspecified
0.000 0.532 0.468
E05.8 Other thyrotoxicosis
0.000 0.533 0.467
G36.9 Acute disseminated demyelination, unspecified
0.464 0.536 0.000
G36.8 Other specified acute disseminated demyelination
0.464 0.536 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.464 0.536 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.538 0.462
E20-E35 Disorders of other endocrine glands
0.000 0.539 0.461
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.547 0.452
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.550 0.449
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.550 0.449
E16.4 Abnormal secretion of gastrin
0.000 0.550 0.449
E16.3 Increased secretion of glucagon
0.000 0.550 0.449
E07.1 Dyshormogenetic goitre
0.000 0.551 0.449
E07.0 Hypersecretion of calcitonin
0.000 0.551 0.449
E83.9 Disorder of mineral metabolism, unspecified
0.448 0.552 0.000
E83.8 Other disorders of mineral metabolism
0.433 0.567 0.000
E83.2 Disorders of zinc metabolism
0.433 0.567 0.000
E83.0 Disorders of copper metabolism
0.433 0.567 0.000
K51.8 Other ulcerative colitis
0.432 0.568 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.582 0.418
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.582 0.418
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.582 0.418
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.582 0.418
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.582 0.418
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.582 0.418
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.582 0.418
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.582 0.418
E23 Hypofunction and other disorders of pituitary gland
0.000 0.583 0.417
E28 Ovarian dysfunction
0.000 0.599 0.401
E11.6 With other specified complications
0.001 0.601 0.399
E83.5 Disorders of calcium metabolism
0.397 0.603 0.000
M06 Other rheumatoid arthritis
0.000 0.617 0.383
E24 Cushing's syndrome
0.000 0.619 0.381
E28.2 Polycystic ovarian syndrome
0.000 0.627 0.373
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.638 0.362
E45 Retarded development following protein-energy malnutrition
0.000 0.638 0.362
E43 Unspecified severe protein-energy malnutrition
0.000 0.638 0.362
E42 Marasmic kwashiorkor
0.000 0.638 0.362
E41 Nutritional marasmus
0.000 0.638 0.362
E40 Kwashiorkor
0.000 0.638 0.362
E23.2 Diabetes insipidus
0.000 0.652 0.348
K51.0 Ulcerative (chronic) enterocolitis
0.346 0.653 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.654 0.346
M06.3 Rheumatoid nodule
0.000 0.661 0.339
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.666 0.334
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.667 0.333
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.670 0.330
E32 Diseases of thymus
0.000 0.670 0.330
E31 Polyglandular dysfunction
0.000 0.670 0.330
E30 Disorders of puberty, not elsewhere classified
0.000 0.670 0.330
E25 Adrenogenital disorders
0.000 0.670 0.330
E23.0 Hypopituitarism
0.000 0.685 0.315
E23.6 Other disorders of pituitary gland
0.000 0.687 0.312
E24.2 Drug-induced Cushing's syndrome
0.000 0.688 0.312
E29 Testicular dysfunction
0.000 0.689 0.311
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.701 0.299
E23.1 Drug-induced hypopituitarism
0.000 0.701 0.299
E24.9 Cushing's syndrome, unspecified
0.000 0.703 0.297
E20 Hypoparathyroidism
0.000 0.704 0.296
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.705 0.295
E21.3 Hyperparathyroidism, unspecified
0.000 0.706 0.294
E28.9 Ovarian dysfunction, unspecified
0.000 0.712 0.288
E28.8 Other ovarian dysfunction
0.000 0.712 0.288
E28.1 Androgen excess
0.000 0.712 0.288
E28.0 Oestrogen excess
0.000 0.712 0.288
E46 Unspecified protein-energy malnutrition
0.000 0.713 0.287
M06.34 Rheumatoid nodule (Hand)
0.000 0.719 0.281
M06.2 Rheumatoid bursitis
0.000 0.725 0.275
M06.1 Adult-onset Still's disease
0.000 0.725 0.275
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.726 0.273
E24.3 Ectopic ACTH syndrome
0.000 0.726 0.273
E24.1 Nelson's syndrome
0.000 0.726 0.273
E24.0 Pituitary-dependent Cushing's disease
0.000 0.726 0.273
E24.8 Other Cushing's syndrome
0.000 0.732 0.267
M06.8 Other specified rheumatoid arthritis
0.000 0.736 0.264
J45 Asthma
0.011 0.736 0.253
M06.4 Inflammatory polyarthropathy
0.000 0.738 0.262
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.740 0.260
E44.1 Mild protein-energy malnutrition
0.000 0.740 0.260
E44.0 Moderate protein-energy malnutrition
0.000 0.740 0.260
L40-L45 Papulosquamous disorders
0.000 0.756 0.244
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.757 0.243
M06.38 Rheumatoid nodule (Other)
0.000 0.757 0.243
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.757 0.243
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.757 0.243
M06.33 Rheumatoid nodule (Forearm)
0.000 0.757 0.243
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.757 0.243
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.757 0.243
E22 Hyperfunction of pituitary gland
0.000 0.758 0.242
E21.4 Other specified disorders of parathyroid gland
0.000 0.761 0.239
E21.2 Other hyperparathyroidism
0.000 0.761 0.239
E26 Hyperaldosteronism
0.000 0.761 0.238
E25.9 Adrenogenital disorder, unspecified
0.000 0.763 0.237
E25.8 Other adrenogenital disorders
0.000 0.763 0.237
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.763 0.237
E30.9 Disorder of puberty, unspecified
0.000 0.763 0.237
E30.8 Other disorders of puberty
0.000 0.763 0.237
E30.1 Precocious puberty
0.000 0.763 0.237
E30.0 Delayed puberty
0.000 0.763 0.237
E31.9 Polyglandular dysfunction, unspecified
0.000 0.763 0.237
E31.8 Other polyglandular dysfunction
0.000 0.763 0.237
E31.1 Polyglandular hyperfunction
0.000 0.763 0.237
E31.0 Autoimmune polyglandular failure
0.000 0.763 0.237
E32.9 Disease of thymus, unspecified
0.000 0.763 0.237
E32.8 Other diseases of thymus
0.000 0.763 0.237
E32.1 Abscess of thymus
0.000 0.763 0.237
E32.0 Persistent hyperplasia of thymus
0.000 0.763 0.237
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.763 0.237
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.763 0.237
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.763 0.237
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.763 0.236
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.768 0.232
E28.3 Primary ovarian failure
0.000 0.770 0.230
K91.4 Colostomy and enterostomy malfunction
0.228 0.772 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.777 0.223
E29.8 Other testicular dysfunction
0.000 0.777 0.223
E29.0 Testicular hyperfunction
0.000 0.777 0.223
E65-E68 Obesity and other hyperalimentation
0.001 0.777 0.222
E20.8 Other hypoparathyroidism
0.000 0.788 0.212
E20.1 Pseudohypoparathyroidism
0.000 0.788 0.212
E20.0 Idiopathic hypoparathyroidism
0.000 0.788 0.212
E29.1 Testicular hypofunction
0.000 0.796 0.204
J45.8 Mixed asthma
0.007 0.798 0.195
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.799 0.201
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.803 0.197
M06.18 Adult-onset Still's disease (Other)
0.000 0.803 0.197
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.803 0.197
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.803 0.197
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.803 0.197
M06.14 Adult-onset Still's disease (Hand)
0.000 0.803 0.197
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.803 0.197
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.803 0.197
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.803 0.197
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.803 0.197
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.803 0.197
M06.28 Rheumatoid bursitis (Other)
0.000 0.803 0.197
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.803 0.197
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.803 0.197
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.803 0.197
M06.24 Rheumatoid bursitis (Hand)
0.000 0.803 0.197
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.803 0.197
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.803 0.197
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.803 0.197
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.803 0.197
J45.1 Nonallergic asthma
0.007 0.810 0.182
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.810 0.189
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.810 0.189
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.810 0.189
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.810 0.189
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.810 0.189
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.810 0.189
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.810 0.189
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.810 0.189
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.810 0.189
E34 Other endocrine disorders
0.001 0.811 0.188
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.812 0.188
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.812 0.188
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.812 0.188
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.812 0.188
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.812 0.188
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.812 0.188
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.812 0.188
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.812 0.188
E06 Thyroiditis
0.002 0.819 0.179
L42 Pityriasis rosea
0.000 0.819 0.181
E11.3 With ophthalmic complications
0.000 0.820 0.180
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.821 0.179
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.821 0.179
E20.9 Hypoparathyroidism, unspecified
0.000 0.822 0.177
L44 Other papulosquamous disorders
0.000 0.825 0.175
L41 Parapsoriasis
0.000 0.825 0.175
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.825 0.175
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.826 0.174
E22.8 Other hyperfunction of pituitary gland
0.000 0.826 0.174
E26.8 Other hyperaldosteronism
0.000 0.829 0.171
E26.1 Secondary hyperaldosteronism
0.000 0.829 0.171
E22.1 Hyperprolactinaemia
0.000 0.837 0.162
E67 Other hyperalimentation
0.001 0.840 0.159
E68 Sequelae of hyperalimentation
0.001 0.840 0.159
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.842 0.158
E26.9 Hyperaldosteronism, unspecified
0.000 0.848 0.151
E50-E64 Other nutritional deficiencies
0.000 0.849 0.150
E27 Other disorders of adrenal gland
0.000 0.855 0.145
E34.5 Androgen resistance syndrome
0.001 0.865 0.135
E34.4 Constitutional tall stature
0.001 0.865 0.135
E34.3 Short stature, not elsewhere classified
0.001 0.865 0.135
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.865 0.135
E34.1 Other hypersecretion of intestinal hormones
0.001 0.865 0.135
E06.4 Drug-induced thyroiditis
0.002 0.870 0.129
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.002 0.870 0.129
E06.0 Acute thyroiditis
0.002 0.870 0.129
E06.5 Other chronic thyroiditis
0.002 0.871 0.128
L41.9 Parapsoriasis, unspecified
0.000 0.874 0.126
L41.8 Other parapsoriasis
0.000 0.874 0.126
L41.5 Retiform parapsoriasis
0.000 0.874 0.126
L41.4 Large plaque parapsoriasis
0.000 0.874 0.126
L41.3 Small plaque parapsoriasis
0.000 0.874 0.126
L41.2 Lymphomatoid papulosis
0.000 0.874 0.126
L41.1 Pityriasis lichenoides chronica
0.000 0.874 0.126
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.874 0.126
L44.9 Papulosquamous disorder, unspecified
0.000 0.874 0.126
L44.8 Other specified papulosquamous disorders
0.000 0.874 0.126
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.874 0.126
L44.3 Lichen ruber moniliformis
0.000 0.874 0.126
L44.2 Lichen striatus
0.000 0.874 0.126
L44.1 Lichen nitidus
0.000 0.874 0.126
L44.0 Pityriasis rubra pilaris
0.000 0.874 0.126
E34.8 Other specified endocrine disorders
0.001 0.876 0.124
J45.0 Predominantly allergic asthma
0.003 0.878 0.119
J40-J47 Chronic lower respiratory diseases
0.058 0.879 0.062
M06.0 Seronegative rheumatoid arthritis
0.000 0.883 0.117
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.883 0.117
E26.0 Primary hyperaldosteronism
0.001 0.885 0.115
E67.8 Other specified hyperalimentation
0.001 0.885 0.114
E67.3 Hypervitaminosis D
0.001 0.885 0.114
E67.2 Megavitamin-B6 syndrome
0.001 0.885 0.114
E67.1 Hypercarotenaemia
0.001 0.885 0.114
E67.0 Hypervitaminosis A
0.001 0.885 0.114
E27.9 Disorder of adrenal gland, unspecified
0.000 0.887 0.113
E34.9 Endocrine disorder, unspecified
0.000 0.888 0.111
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.892 0.108
E63 Other nutritional deficiencies
0.000 0.892 0.108
E50 Vitamin A deficiency
0.000 0.892 0.108
E60 Dietary zinc deficiency
0.000 0.892 0.108
E59 Dietary selenium deficiency
0.000 0.892 0.108
E54 Ascorbic acid deficiency
0.000 0.892 0.108
E52 Niacin deficiency [pellagra]
0.000 0.892 0.108
E56 Other vitamin deficiencies
0.000 0.895 0.105
E27.5 Adrenomedullary hyperfunction
0.000 0.895 0.104
E27.0 Other adrenocortical overactivity
0.000 0.895 0.104
E06.1 Subacute thyroiditis
0.002 0.897 0.101
E58 Dietary calcium deficiency
0.000 0.900 0.099
E51 Thiamine deficiency
0.000 0.902 0.098
E22.0 Acromegaly and pituitary gigantism
0.000 0.902 0.098
L43 Lichen planus
0.000 0.911 0.089
J41 Simple and mucopurulent chronic bronchitis
0.044 0.915 0.041
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.916 0.084
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.916 0.084
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.916 0.084
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.916 0.084
E65 Localised adiposity
0.001 0.917 0.082
E55 Vitamin D deficiency
0.000 0.918 0.081
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.920 0.080
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.920 0.080
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.920 0.080
K50-K52 Noninfective enteritis and colitis
0.079 0.920 0.000
K90-K93 Other diseases of the digestive system
0.001 0.922 0.077
E50.9 Vitamin A deficiency, unspecified
0.000 0.922 0.078
E50.8 Other manifestations of vitamin A deficiency
0.000 0.922 0.078
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.922 0.078
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.922 0.078
E50.5 Vitamin A deficiency with night blindness
0.000 0.922 0.078
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.922 0.078
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.922 0.078
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.922 0.078
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.922 0.078
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.922 0.078
E63.9 Nutritional deficiency, unspecified
0.000 0.922 0.078
E63.8 Other specified nutritional deficiencies
0.000 0.922 0.078
E63.1 Imbalance of constituents of food intake
0.000 0.922 0.078
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.922 0.078
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.922 0.078
E64.8 Sequelae of other nutritional deficiencies
0.000 0.922 0.078
E64.3 Sequelae of rickets
0.000 0.922 0.078
E64.2 Sequelae of vitamin C deficiency
0.000 0.922 0.078
E64.1 Sequelae of vitamin A deficiency
0.000 0.922 0.078
E64.0 Sequelae of protein-energy malnutrition
0.000 0.922 0.078
E34.0 Carcinoid syndrome
0.001 0.923 0.076
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.923 0.077
I10 Essential (primary) hypertension
0.000 0.923 0.077
E56.9 Vitamin deficiency, unspecified
0.000 0.925 0.075
E56.8 Deficiency of other vitamins
0.000 0.925 0.075
E56.0 Deficiency of vitamin E
0.000 0.925 0.075
E61 Deficiency of other nutrient elements
0.000 0.925 0.074
J46 Status asthmaticus
0.004 0.926 0.070
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.926 0.074
E27.2 Addisonian crisis
0.000 0.927 0.073
E56.1 Deficiency of vitamin K
0.000 0.928 0.072
E51.9 Thiamine deficiency, unspecified
0.000 0.929 0.070
E51.8 Other manifestations of thiamine deficiency
0.000 0.929 0.070
E51.1 Beriberi
0.000 0.929 0.070
E27.8 Other specified disorders of adrenal gland
0.000 0.931 0.069
E27.1 Primary adrenocortical insufficiency
0.000 0.933 0.066
E06.9 Thyroiditis, unspecified
0.003 0.935 0.063
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.935 0.065
L43.3 Subacute (active) lichen planus
0.000 0.936 0.064
L43.2 Lichenoid drug reaction
0.000 0.936 0.064
L43.1 Bullous lichen planus
0.000 0.936 0.064
L43.0 Hypertrophic lichen planus
0.000 0.936 0.064
J42 Unspecified chronic bronchitis
0.048 0.938 0.015
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.032 0.939 0.030
J41.1 Mucopurulent chronic bronchitis
0.032 0.939 0.030
E51.2 Wernicke's encephalopathy
0.001 0.939 0.060
J43 Emphysema
0.024 0.940 0.036
J41.0 Simple chronic bronchitis
0.033 0.940 0.027
J40 Bronchitis, not specified as acute or chronic
0.056 0.941 0.003
E55.0 Rickets, active
0.000 0.941 0.058
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.941 0.058
K93 Disorders of other digestive organs in diseases classified elsewhere
0.001 0.944 0.055
E06.3 Autoimmune thyroiditis
0.002 0.946 0.052
E61.9 Deficiency of nutrient element, unspecified
0.000 0.946 0.053
E61.8 Deficiency of other specified nutrient elements
0.000 0.946 0.053
E61.7 Deficiency of multiple nutrient elements
0.000 0.946 0.053
E61.6 Vanadium deficiency
0.000 0.946 0.053
E61.5 Molybdenum deficiency
0.000 0.946 0.053
E61.4 Chromium deficiency
0.000 0.946 0.053
E61.3 Manganese deficiency
0.000 0.946 0.053
E61.0 Copper deficiency
0.000 0.946 0.053
K60.2 Anal fissure, unspecified
0.000 0.947 0.053
E53 Deficiency of other B group vitamins
0.000 0.950 0.050
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.047 0.953 0.000
E04 Other non-toxic goitre
0.001 0.954 0.045
I10-I15 Hypertensive diseases
0.000 0.955 0.045
E21.0 Primary hyperparathyroidism
0.000 0.956 0.044
J43.1 Panlobular emphysema
0.017 0.956 0.026
J43.0 MacLeod's syndrome
0.017 0.956 0.026
J43.8 Other emphysema
0.016 0.957 0.027
E61.2 Magnesium deficiency
0.001 0.959 0.041
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.001 0.959 0.040
K93.1 Megacolon in Chagas' disease
0.001 0.959 0.040
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.001 0.959 0.040
E61.1 Iron deficiency
0.000 0.960 0.040
L43.8 Other lichen planus
0.001 0.960 0.039
I12 Hypertensive renal disease
0.000 0.961 0.039
J43.2 Centrilobular emphysema
0.018 0.962 0.020
I11 Hypertensive heart disease
0.000 0.963 0.037
E53.1 Pyridoxine deficiency
0.000 0.964 0.036
E53.0 Riboflavin deficiency
0.000 0.964 0.036
E66 Obesity
0.001 0.966 0.033
E04.8 Other specified non-toxic goitre
0.001 0.967 0.032
E70-E90 Metabolic disorders
0.002 0.967 0.031
I12.9 Hypertensive renal disease without renal failure
0.000 0.967 0.033
L43.9 Lichen planus, unspecified
0.000 0.967 0.033
I12.0 Hypertensive renal disease with renal failure
0.000 0.968 0.032
E55.9 Vitamin D deficiency, unspecified
0.000 0.968 0.032
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.031 0.969 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.010 0.970 0.021
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.970 0.030
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.970 0.030
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.030 0.970 0.000
I15 Secondary hypertension
0.000 0.971 0.029
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.028 0.972 0.000
E04.0 Non-toxic diffuse goitre
0.001 0.972 0.027
E88 Other metabolic disorders
0.000 0.972 0.027
I13 Hypertensive heart and renal disease
0.000 0.973 0.027
K56.2 Volvulus
0.027 0.973 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.001 0.973 0.026
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.974 0.026
K52 Other non-infective gastro-enteritis and colitis
0.026 0.974 0.000
J98.4 Other disorders of lung
0.000 0.974 0.026
E53.9 Vitamin B deficiency, unspecified
0.001 0.975 0.025
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.975 0.025
E79 Disorders of purine and pyrimidine metabolism
0.001 0.975 0.024
E74 Other disorders of carbohydrate metabolism
0.001 0.975 0.024
E66.1 Drug-induced obesity
0.001 0.975 0.024
M05-M14 Inflammatory polyarthropathies
0.000 0.975 0.025
J43.9 Emphysema, unspecified
0.001 0.976 0.024
E77 Disorders of glycoprotein metabolism
0.001 0.976 0.023
E76 Disorders of glycosaminoglycan metabolism
0.001 0.976 0.023
E72 Other disorders of amino-acid metabolism
0.001 0.976 0.023
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.976 0.023
E70 Disorders of aromatic amino-acid metabolism
0.001 0.976 0.023
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.976 0.023
I15.9 Seconday hypertension, unspecified
0.000 0.976 0.024

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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