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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2395004
log Bayes Factor = 140.498
Chromosome 6   position 31,412,513  (GRCh37) Explore rs2395004 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
J45.9 Asthma, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E03 Other hypothyroidism
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
E03.9 Hypothyroidism, unspecified
0.998 0.002 0.000
L40.5 Arthropathic psoriasis
0.000 0.005 0.995
E10.3 With ophthalmic complications
0.994 0.006 0.000
L40 Psoriasis
0.000 0.006 0.994
L40.9 Psoriasis, unspecified
0.000 0.006 0.994
E14 Unspecified diabetes mellitus
0.980 0.020 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.980 0.020 0.000
E10.1 With ketoacidosis
0.978 0.022 0.000
M45 Ankylosing spondylitis
0.000 0.026 0.974
E16 Other disorders of pancreatic internal secretion
0.966 0.034 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.042 0.958
E05.0 Thyrotoxicosis with diffuse goitre
0.950 0.050 0.000
E10.0 With coma
0.942 0.058 0.000
E16.2 Hypoglycaemia, unspecified
0.940 0.060 0.000
E10.2 With renal complications
0.923 0.077 0.000
E14.3 With ophthalmic complications
0.911 0.089 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.902 0.098 0.000
E13 Other specified diabetes mellitus
0.876 0.124 0.000
L40.0 Psoriasis vulgaris
0.000 0.141 0.859
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.159 0.841
E14.2 Withrenal complications
0.835 0.165 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.823 0.177 0.000
K90 Intestinal malabsorption
0.819 0.181 0.000
E13.9 Without complications
0.799 0.201 0.000
E14.8 With unspecified complications
0.788 0.212 0.000
E14.6 With other specified complications
0.787 0.213 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.214 0.786
L40.4 Guttate psoriasis
0.000 0.219 0.781
E16.1 Other hypoglycaemia
0.763 0.237 0.000
E14.1 With ketoacidosis
0.761 0.239 0.000
L40.1 Generalised pustular psoriasis
0.000 0.253 0.747
E14.5 With peripheral circulatory complications
0.741 0.259 0.000
K90.9 Intestinal malabsorption, unspecified
0.736 0.264 0.000
E03.8 Other specified hypothyroidism
0.735 0.265 0.000
E10.6 With other specified complications
0.735 0.265 0.000
E10.8 With unspecified complications
0.731 0.269 0.000
E10.4 With neurological complications
0.729 0.271 0.000
E14.0 With coma
0.722 0.278 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.716 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.716 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.716 0.283 0.000
L40.2 Acrodermatitis continua
0.000 0.287 0.713
E07 Other disorders of thyroid
0.710 0.290 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.708 0.292 0.000
E03.1 Congenital hypothyroidism without goitre
0.706 0.294 0.000
E40-E46 Malnutrition
0.704 0.296 0.000
E14.7 With multiple complications
0.702 0.297 0.000
E15 Nondiabetic hypoglycaemic coma
0.702 0.298 0.000
E10.7 With multiple complications
0.702 0.298 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.301 0.698
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.301 0.698
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.301 0.698
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.301 0.698
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.301 0.698
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.301 0.698
L40.3 Pustulosis palmaris et plantaris
0.000 0.303 0.697
E16.9 Disorder of pancreatic internal secretion, unspecified
0.692 0.308 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.692 0.308 0.000
E16.4 Abnormal secretion of gastrin
0.692 0.308 0.000
E16.3 Increased secretion of glucagon
0.692 0.308 0.000
K90.8 Other intestinal malabsorption
0.690 0.310 0.000
E05.8 Other thyrotoxicosis
0.687 0.313 0.000
E14.9 Without complications
0.677 0.323 0.000
E14.4 With neurological complications
0.645 0.355 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.644 0.356 0.000
L40.8 Other psoriasis
0.000 0.361 0.639
E13.8 With unspecified complications
0.628 0.371 0.000
E13.7 With multiple complications
0.628 0.371 0.000
E13.6 With other specified complications
0.628 0.371 0.000
E13.5 With peripheral circulatory complications
0.628 0.371 0.000
E13.4 With neurological complications
0.628 0.371 0.000
E13.2 With renal complications
0.628 0.371 0.000
E13.1 With ketoacidosis
0.628 0.371 0.000
E13.0 With coma
0.628 0.371 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.615 0.385 0.000
E13.3 With ophthalmic complications
0.594 0.406 0.000
K90.3 Pancreatic steatorrhoea
0.587 0.412 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.587 0.412 0.000
K90.1 Tropical sprue
0.587 0.412 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.580 0.420 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.574 0.425 0.000
J45 Asthma
0.570 0.430 0.000
E07.8 Other specified disorders of thyroid
0.550 0.450 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.539 0.461 0.000
E10.5 With peripheral circulatory complications
0.531 0.469 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E07.1 Dyshormogenetic goitre
0.509 0.491 0.000
E07.0 Hypersecretion of calcitonin
0.509 0.491 0.000
J45.1 Nonallergic asthma
0.509 0.491 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.505 0.495 0.000
E45 Retarded development following protein-energy malnutrition
0.505 0.495 0.000
E43 Unspecified severe protein-energy malnutrition
0.505 0.495 0.000
E42 Marasmic kwashiorkor
0.505 0.495 0.000
E41 Nutritional marasmus
0.505 0.495 0.000
E40 Kwashiorkor
0.505 0.495 0.000
E46 Unspecified protein-energy malnutrition
0.492 0.507 0.000
E07.9 Disorder of thyroid, unspecified
0.451 0.549 0.000
J45.8 Mixed asthma
0.434 0.566 0.000
E65-E68 Obesity and other hyperalimentation
0.396 0.567 0.037
E20-E35 Disorders of other endocrine glands
0.399 0.601 0.000
E11 Non-insulin-dependent diabetes mellitus
0.386 0.614 0.000
E44.1 Mild protein-energy malnutrition
0.362 0.638 0.000
E44.0 Moderate protein-energy malnutrition
0.362 0.638 0.000
E11.1 With ketoacidosis
0.349 0.651 0.000
E06 Thyroiditis
0.341 0.659 0.000
E50-E64 Other nutritional deficiencies
0.340 0.660 0.000
E11.0 With coma
0.318 0.682 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.318 0.682 0.000
E67 Other hyperalimentation
0.284 0.689 0.027
E68 Sequelae of hyperalimentation
0.284 0.689 0.027
E31 Polyglandular dysfunction
0.308 0.692 0.000
E11.7 With multiple complications
0.306 0.694 0.000
E25 Adrenogenital disorders
0.298 0.701 0.000
E11.6 With other specified complications
0.295 0.705 0.000
J45.0 Predominantly allergic asthma
0.295 0.705 0.000
G35 Multiple sclerosis
0.000 0.707 0.293
E20 Hypoparathyroidism
0.290 0.710 0.000
E23 Hypofunction and other disorders of pituitary gland
0.289 0.711 0.000
E11.5 With peripheral circulatory complications
0.289 0.711 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.286 0.714 0.000
E32 Diseases of thymus
0.286 0.714 0.000
E30 Disorders of puberty, not elsewhere classified
0.286 0.714 0.000
E22 Hyperfunction of pituitary gland
0.283 0.717 0.000
E66.8 Other obesity
0.000 0.725 0.274
E65 Localised adiposity
0.250 0.727 0.023
E24 Cushing's syndrome
0.268 0.732 0.000
E11.8 With unspecified complications
0.266 0.734 0.000
E27 Other disorders of adrenal gland
0.266 0.734 0.000
E23.2 Diabetes insipidus
0.265 0.735 0.000
E21.3 Hyperparathyroidism, unspecified
0.265 0.735 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.000 0.736 0.264
E29 Testicular dysfunction
0.261 0.739 0.000
E27.1 Primary adrenocortical insufficiency
0.253 0.747 0.000
E51 Thiamine deficiency
0.246 0.753 0.000
E06.4 Drug-induced thyroiditis
0.245 0.755 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.245 0.755 0.000
E06.0 Acute thyroiditis
0.245 0.755 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.244 0.756 0.000
E63 Other nutritional deficiencies
0.244 0.756 0.000
E50 Vitamin A deficiency
0.244 0.756 0.000
E60 Dietary zinc deficiency
0.244 0.756 0.000
E59 Dietary selenium deficiency
0.244 0.756 0.000
E52 Niacin deficiency [pellagra]
0.244 0.756 0.000
E31.0 Autoimmune polyglandular failure
0.243 0.756 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.243 0.757 0.000
E21.4 Other specified disorders of parathyroid gland
0.243 0.757 0.000
E28 Ovarian dysfunction
0.241 0.759 0.000
E54 Ascorbic acid deficiency
0.241 0.759 0.000
E06.5 Other chronic thyroiditis
0.239 0.760 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.238 0.762 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.232 0.768 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.226 0.773 0.000
E67.8 Other specified hyperalimentation
0.204 0.777 0.019
E67.3 Hypervitaminosis D
0.204 0.777 0.019
E67.2 Megavitamin-B6 syndrome
0.204 0.777 0.019
E67.1 Hypercarotenaemia
0.204 0.777 0.019
E67.0 Hypervitaminosis A
0.204 0.777 0.019
E31.9 Polyglandular dysfunction, unspecified
0.221 0.779 0.000
E31.8 Other polyglandular dysfunction
0.221 0.779 0.000
E31.1 Polyglandular hyperfunction
0.221 0.779 0.000
E56 Other vitamin deficiencies
0.220 0.779 0.000
E24.2 Drug-induced Cushing's syndrome
0.215 0.785 0.000
E21.2 Other hyperparathyroidism
0.214 0.786 0.000
E25.9 Adrenogenital disorder, unspecified
0.214 0.786 0.000
E25.8 Other adrenogenital disorders
0.214 0.786 0.000
E06.9 Thyroiditis, unspecified
0.212 0.788 0.000
E20.9 Hypoparathyroidism, unspecified
0.212 0.788 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.789 0.211
E53 Deficiency of other B group vitamins
0.211 0.789 0.000
E06.1 Subacute thyroiditis
0.210 0.790 0.001
E20.8 Other hypoparathyroidism
0.208 0.792 0.000
E20.1 Pseudohypoparathyroidism
0.208 0.792 0.000
E20.0 Idiopathic hypoparathyroidism
0.208 0.792 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.208 0.792 0.000
E23.1 Drug-induced hypopituitarism
0.208 0.792 0.000
E55 Vitamin D deficiency
0.205 0.794 0.000
E30.9 Disorder of puberty, unspecified
0.205 0.795 0.000
E30.8 Other disorders of puberty
0.205 0.795 0.000
E30.1 Precocious puberty
0.205 0.795 0.000
E30.0 Delayed puberty
0.205 0.795 0.000
E32.9 Disease of thymus, unspecified
0.205 0.795 0.000
E32.8 Other diseases of thymus
0.205 0.795 0.000
E32.1 Abscess of thymus
0.205 0.795 0.000
E32.0 Persistent hyperplasia of thymus
0.205 0.795 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.205 0.795 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.205 0.795 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.205 0.795 0.000
E11.2 With renal complications
0.204 0.796 0.000
E23.6 Other disorders of pituitary gland
0.204 0.796 0.000
E61 Deficiency of other nutrient elements
0.203 0.796 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.203 0.797 0.000
E22.8 Other hyperfunction of pituitary gland
0.203 0.797 0.000
E22.1 Hyperprolactinaemia
0.201 0.798 0.000
E21.0 Primary hyperparathyroidism
0.198 0.802 0.000
E34 Other endocrine disorders
0.197 0.803 0.000
E58 Dietary calcium deficiency
0.197 0.803 0.000
E23.7 Disorder of pituitary gland, unspecified
0.195 0.805 0.000
E29.9 Testicular dysfunction, unspecified
0.193 0.807 0.000
E24.8 Other Cushing's syndrome
0.192 0.808 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.192 0.808 0.000
E24.3 Ectopic ACTH syndrome
0.192 0.808 0.000
E24.1 Nelson's syndrome
0.192 0.808 0.000
E26 Hyperaldosteronism
0.191 0.809 0.000
E27.5 Adrenomedullary hyperfunction
0.190 0.809 0.000
E27.0 Other adrenocortical overactivity
0.190 0.809 0.000
G37 Other demyelinating diseases of central nervous system
0.000 0.811 0.189
E29.8 Other testicular dysfunction
0.187 0.812 0.000
E29.0 Testicular hyperfunction
0.187 0.812 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.185 0.815 0.000
L40-L45 Papulosquamous disorders
0.000 0.818 0.182
E51.2 Wernicke's encephalopathy
0.179 0.820 0.000
E24.0 Pituitary-dependent Cushing's disease
0.178 0.822 0.000
E51.9 Thiamine deficiency, unspecified
0.177 0.823 0.000
E51.8 Other manifestations of thiamine deficiency
0.177 0.823 0.000
E51.1 Beriberi
0.177 0.823 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.177 0.823 0.000
E50.9 Vitamin A deficiency, unspecified
0.175 0.825 0.000
E50.8 Other manifestations of vitamin A deficiency
0.175 0.825 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.175 0.825 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.175 0.825 0.000
E50.5 Vitamin A deficiency with night blindness
0.175 0.825 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.175 0.825 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.175 0.825 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.175 0.825 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.175 0.825 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.175 0.825 0.000
E63.9 Nutritional deficiency, unspecified
0.175 0.825 0.000
E63.8 Other specified nutritional deficiencies
0.175 0.825 0.000
E63.1 Imbalance of constituents of food intake
0.175 0.825 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.175 0.825 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.175 0.825 0.000
E64.8 Sequelae of other nutritional deficiencies
0.175 0.825 0.000
E64.3 Sequelae of rickets
0.175 0.825 0.000
E64.2 Sequelae of vitamin C deficiency
0.175 0.825 0.000
E64.1 Sequelae of vitamin A deficiency
0.175 0.825 0.000
E64.0 Sequelae of protein-energy malnutrition
0.175 0.825 0.000
E28.9 Ovarian dysfunction, unspecified
0.173 0.827 0.000
E28.8 Other ovarian dysfunction
0.173 0.827 0.000
E28.1 Androgen excess
0.173 0.827 0.000
E28.0 Oestrogen excess
0.173 0.827 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.830 0.170
E28.3 Primary ovarian failure
0.168 0.831 0.000
G36 Other acute disseminated demyelination
0.000 0.834 0.166
E56.9 Vitamin deficiency, unspecified
0.158 0.842 0.000
E56.8 Deficiency of other vitamins
0.158 0.842 0.000
E56.0 Deficiency of vitamin E
0.158 0.842 0.000
E24.9 Cushing's syndrome, unspecified
0.155 0.845 0.000
E29.1 Testicular hypofunction
0.155 0.845 0.000
E27.2 Addisonian crisis
0.152 0.848 0.000
E61.2 Magnesium deficiency
0.152 0.848 0.000
E66 Obesity
0.056 0.848 0.096
E53.1 Pyridoxine deficiency
0.151 0.849 0.000
E53.0 Riboflavin deficiency
0.151 0.849 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.851 0.149
E55.0 Rickets, active
0.147 0.852 0.000
E61.9 Deficiency of nutrient element, unspecified
0.146 0.854 0.000
E61.8 Deficiency of other specified nutrient elements
0.146 0.854 0.000
E61.7 Deficiency of multiple nutrient elements
0.146 0.854 0.000
E61.6 Vanadium deficiency
0.146 0.854 0.000
E61.5 Molybdenum deficiency
0.146 0.854 0.000
E61.4 Chromium deficiency
0.146 0.854 0.000
E61.3 Manganese deficiency
0.146 0.854 0.000
E61.0 Copper deficiency
0.146 0.854 0.000
E53.8 Deficiency of other specified B group vitamins
0.146 0.854 0.000
E34.3 Short stature, not elsewhere classified
0.145 0.855 0.000
E34.5 Androgen resistance syndrome
0.142 0.858 0.000
E34.4 Constitutional tall stature
0.142 0.858 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.142 0.858 0.000
E34.1 Other hypersecretion of intestinal hormones
0.142 0.858 0.000
E27.9 Disorder of adrenal gland, unspecified
0.140 0.860 0.000
E26.8 Other hyperaldosteronism
0.137 0.863 0.000
E26.1 Secondary hyperaldosteronism
0.137 0.863 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.864 0.136
G37.4 Subacute necrotising myelitis
0.000 0.864 0.136
G37.2 Central pontine myelinolysis
0.000 0.864 0.136
G37.1 Central demyelination of corpus callosum
0.000 0.864 0.136
G37.0 Diffuse sclerosis
0.000 0.864 0.136
E56.1 Deficiency of vitamin K
0.135 0.865 0.000
E28.2 Polycystic ovarian syndrome
0.135 0.865 0.000
E34.8 Other specified endocrine disorders
0.135 0.865 0.000
G36.0 Neuromyelitis optica [Devic]
0.000 0.866 0.134
L41 Parapsoriasis
0.000 0.869 0.130
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.869 0.130
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.870 0.130
E53.9 Vitamin B deficiency, unspecified
0.126 0.874 0.000
L44 Other papulosquamous disorders
0.000 0.878 0.122
L42 Pityriasis rosea
0.000 0.878 0.122
E22.0 Acromegaly and pituitary gigantism
0.121 0.879 0.000
G36.9 Acute disseminated demyelination, unspecified
0.000 0.881 0.119
G36.8 Other specified acute disseminated demyelination
0.000 0.881 0.119
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.881 0.119
E26.9 Hyperaldosteronism, unspecified
0.117 0.882 0.001
E34.0 Carcinoid syndrome
0.115 0.885 0.000
E55.9 Vitamin D deficiency, unspecified
0.109 0.891 0.000
E66.1 Drug-induced obesity
0.040 0.891 0.069
E66.0 Obesity due to excess calories
0.029 0.895 0.076
E34.9 Endocrine disorder, unspecified
0.105 0.895 0.000
E27.8 Other specified disorders of adrenal gland
0.102 0.897 0.000
E11.4 With neurological complications
0.101 0.899 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.041 0.902 0.058
E06.3 Autoimmune thyroiditis
0.095 0.904 0.001
E61.1 Iron deficiency
0.095 0.905 0.000
L41.9 Parapsoriasis, unspecified
0.000 0.906 0.094
L41.8 Other parapsoriasis
0.000 0.906 0.094
L41.5 Retiform parapsoriasis
0.000 0.906 0.094
L41.4 Large plaque parapsoriasis
0.000 0.906 0.094
L41.3 Small plaque parapsoriasis
0.000 0.906 0.094
L41.2 Lymphomatoid papulosis
0.000 0.906 0.094
L41.1 Pityriasis lichenoides chronica
0.000 0.906 0.094
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.906 0.094
L44.9 Papulosquamous disorder, unspecified
0.000 0.912 0.087
L44.8 Other specified papulosquamous disorders
0.000 0.912 0.087
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.912 0.087
L44.3 Lichen ruber moniliformis
0.000 0.912 0.087
L44.2 Lichen striatus
0.000 0.912 0.087
L44.1 Lichen nitidus
0.000 0.912 0.087
K90-K93 Other diseases of the digestive system
0.087 0.913 0.000
E11.9 Without complications
0.086 0.914 0.000
K60.2 Anal fissure, unspecified
0.084 0.916 0.000
E11.3 With ophthalmic complications
0.083 0.917 0.000
E26.0 Primary hyperaldosteronism
0.081 0.919 0.001
L44.0 Pityriasis rubra pilaris
0.000 0.921 0.079
E23.0 Hypopituitarism
0.073 0.927 0.000
E04 Other non-toxic goitre
0.072 0.928 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.063 0.937 0.000
L43 Lichen planus
0.000 0.940 0.059
Z83.7 Family history of diseases of the digestive system
0.059 0.941 0.000
Z83 Family history of other specific disorders
0.053 0.947 0.000
E04.8 Other specified non-toxic goitre
0.052 0.948 0.000
Z83.5 Family history of eye and ear disorders
0.048 0.952 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.046 0.954 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.045 0.955 0.000
K93.1 Megacolon in Chagas' disease
0.045 0.955 0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.045 0.955 0.000
K91.3 Postoperative intestinal obstruction
0.045 0.955 0.000
Z83.1 Family history of other infectious and parasitic diseases
0.044 0.956 0.000
Z83.6 Family history of diseases of the respiratory system
0.043 0.957 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.043 0.957 0.000
L43.3 Subacute (active) lichen planus
0.000 0.957 0.043
L43.2 Lichenoid drug reaction
0.000 0.957 0.043
L43.1 Bullous lichen planus
0.000 0.957 0.043
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.958 0.042
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.042 0.958 0.000
E04.0 Non-toxic diffuse goitre
0.041 0.959 0.000
L43.8 Other lichen planus
0.000 0.960 0.039
Z83.0 Family history of human immunodeficiency virus [HIV]
0.038 0.962 0.000
L43.0 Hypertrophic lichen planus
0.000 0.963 0.036
N48.6 Balanitis xerotica obliterans
0.035 0.965 0.000
R31 Unspecified haematuria
0.000 0.967 0.033
M45-M49 Spondylopathies
0.000 0.967 0.033
K91.5 Postcholecystectomy syndrome
0.033 0.967 0.000
K91.1 Postgastric surgery syndromes
0.030 0.970 0.000
N48 Other disorders of penis
0.029 0.971 0.000
N48.0 Leukoplakia of penis
0.028 0.972 0.000
E04.1 Non-toxic single thyroid nodule
0.028 0.972 0.000
N40-N51 Diseases of male genital organs
0.027 0.973 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.027 0.973 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.026 0.974 0.000
N48.9 Disorder of penis, unspecified
0.026 0.974 0.000
G20 Parkinson's disease
0.000 0.976 0.024
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.023 0.977 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.022 0.978 0.000
M49 Spondylopathies in diseases classified elsewhere
0.000 0.979 0.021
H20.9 Iridocyclitis, unspecified
0.000 0.979 0.021
J33.0 Polyp of nasal cavity
0.021 0.979 0.000
N48.8 Other specified disorders of penis
0.021 0.979 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.020 0.980 0.000
N49.8 Inflammatory disorders of other specified male genital organs
0.020 0.980 0.000
N48.5 Ulcer of penis
0.019 0.981 0.000
Z83.3 Family history of diabetes mellitus
0.019 0.981 0.000
J33.9 Nasal polyp, unspecified
0.018 0.982 0.000
N49.2 Inflammatory disorders of scrotum
0.018 0.982 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.017 0.982 0.000
N46 Male infertility
0.018 0.982 0.000
N44 Torsion of testis
0.017 0.983 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.017 0.983 0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.017 0.983 0.000
N49.0 Inflammatory disorders of seminal vesicle
0.017 0.983 0.000
H20 Iridocyclitis
0.000 0.983 0.017
J33 Nasal polyp
0.017 0.983 0.000
N48.2 Other inflammatory disorders of penis
0.016 0.984 0.000
H20.1 Chronic iridocyclitis
0.000 0.984 0.016
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.984 0.015
M49.4 Neuropathic spondylopathy
0.000 0.984 0.015
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.984 0.015
M49.2 Enterobacterial spondylitis
0.000 0.984 0.015
M49.1 Brucella spondylitis
0.000 0.984 0.015
M49.0 Tuberculosis of spine
0.000 0.984 0.015
N48.4 Impotence of organic origin
0.015 0.985 0.000
N42 Other disorders of prostate
0.015 0.985 0.000
M48 Other spondylopathies
0.000 0.985 0.015
N42.1 Congestion and haemorrhage of prostate
0.015 0.985 0.000
N51.2 Balanitis in diseases classified elsewhere
0.015 0.985 0.000
N83.1 Corpus luteum cyst
0.015 0.985 0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.014 0.985 0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.014 0.985 0.000
N51.0 Disorders of prostate in diseases classified elsewhere
0.014 0.985 0.000
N48.3 Priapism
0.013 0.986 0.000
H20.0 Acute and subacute iridocyclitis
0.000 0.986 0.013
J33.1 Polypoid sinus degeneration
0.013 0.987 0.000
N43 Hydrocele and spermatocele
0.013 0.987 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.987 0.013
M48.5 Collapsed vertebra, not elsewhere classified
0.000 0.987 0.013
H20.2 Lens-induced iridocyclitis
0.000 0.988 0.012
H20.8 Other iridocyclitis
0.000 0.988 0.012
K60 Fissure and fistula of anal and rectal regions
0.011 0.989 0.000
M49.09 Tuberculosis of spine (Site unspecified)
0.000 0.989 0.011
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.000 0.989 0.011
M49.07 Tuberculosis of spine (Lumbosacral region)
0.000 0.989 0.011
M49.06 Tuberculosis of spine (Lumbar region)
0.000 0.989 0.011
M49.05 Tuberculosis of spine (Thoracolumbar region)
0.000 0.989 0.011
M49.04 Tuberculosis of spine (Thoracic region)
0.000 0.989 0.011
M49.03 Tuberculosis of spine (Cervicothoracic region)
0.000 0.989 0.011
M49.02 Tuberculosis of spine (Cervical region)
0.000 0.989 0.011
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)
0.000 0.989 0.011
M49.00 Tuberculosis of spine (Multiple sites in spine)
0.000 0.989 0.011
M49.19 Brucella spondylitis (Site unspecified)
0.000 0.989 0.011
M49.18 Brucella spondylitis (Sacral and sacrococcygeal region)
0.000 0.989 0.011
M49.17 Brucella spondylitis (Lumbosacral region)
0.000 0.989 0.011
M49.16 Brucella spondylitis (Lumbar region)
0.000 0.989 0.011
M49.15 Brucella spondylitis (Thoracolumbar region)
0.000 0.989 0.011
M49.14 Brucella spondylitis (Thoracic region)
0.000 0.989 0.011
M49.13 Brucella spondylitis (Cervicothoracic region)
0.000 0.989 0.011
M49.12 Brucella spondylitis (Cervical region)
0.000 0.989 0.011
M49.11 Brucella spondylitis (Occipito-atlanto-axial region)
0.000 0.989 0.011
M49.10 Brucella spondylitis (Multiple sites in spine)
0.000 0.989 0.011
M49.29 Enterobacterial spondylitis (Site unspecified)
0.000 0.989 0.011
M49.28 Enterobacterial spondylitis (Sacral and sacrococcygeal region)
0.000 0.989 0.011
M49.27 Enterobacterial spondylitis (Lumbosacral region)
0.000 0.989 0.011
M49.26 Enterobacterial spondylitis (Lumbar region)
0.000 0.989 0.011
M49.25 Enterobacterial spondylitis (Thoracolumbar region)
0.000 0.989 0.011
M49.24 Enterobacterial spondylitis (Thoracic region)
0.000 0.989 0.011
M49.23 Enterobacterial spondylitis (Cervicothoracic region)
0.000 0.989 0.011
M49.22 Enterobacterial spondylitis (Cervical region)
0.000 0.989 0.011
M49.21 Enterobacterial spondylitis (Occipito-atlanto-axial region)
0.000 0.989 0.011
M49.20 Enterobacterial spondylitis (Multiple sites in spine)
0.000 0.989 0.011
M49.39 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Site unspecified)
0.000 0.989 0.011
M49.38 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Sacral and sacrococcygeal region)
0.000 0.989 0.011
M49.37 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbosacral region)
0.000 0.989 0.011
M49.36 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbar region)
0.000 0.989 0.011
M49.35 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracolumbar region)
0.000 0.989 0.011
M49.34 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracic region)
0.000 0.989 0.011
M49.33 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervicothoracic region)
0.000 0.989 0.011
M49.32 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervical region)
0.000 0.989 0.011
M49.31 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Occipito-atlanto-axial region)
0.000 0.989 0.011
M49.30 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Multiple sites in spine)
0.000 0.989 0.011
M49.49 Neuropathic spondylopathy (Site unspecified)
0.000 0.989 0.011
M49.48 Neuropathic spondylopathy (Sacral and sacrococcygeal region)
0.000 0.989 0.011
M49.47 Neuropathic spondylopathy (Lumbosacral region)
0.000 0.989 0.011
M49.46 Neuropathic spondylopathy (Lumbar region)
0.000 0.989 0.011
M49.45 Neuropathic spondylopathy (Thoracolumbar region)
0.000 0.989 0.011
M49.44 Neuropathic spondylopathy (Thoracic region)
0.000 0.989 0.011
M49.43 Neuropathic spondylopathy (Cervicothoracic region)
0.000 0.989 0.011
M49.42 Neuropathic spondylopathy (Cervical region)
0.000 0.989 0.011
M49.41 Neuropathic spondylopathy (Occipito-atlanto-axial region)
0.000 0.989 0.011
M49.40 Neuropathic spondylopathy (Multiple sites in spine)
0.000 0.989 0.011
M49.89 Spondylopathy in other diseases classified elsewhere (Site unspecified)
0.000 0.989 0.011
M49.88 Spondylopathy in other diseases classified elsewhere (Sacral and sacrococcygeal region)
0.000 0.989 0.011
M49.87 Spondylopathy in other diseases classified elsewhere (Lumbosacral region)
0.000 0.989 0.011
M49.86 Spondylopathy in other diseases classified elsewhere (Lumbar region)
0.000 0.989 0.011
M49.85 Spondylopathy in other diseases classified elsewhere (Thoracolumbar region)
0.000 0.989 0.011
M49.84 Spondylopathy in other diseases classified elsewhere (Thoracic region)
0.000 0.989 0.011
M49.83 Spondylopathy in other diseases classified elsewhere (Cervicothoracic region)
0.000 0.989 0.011
M49.82 Spondylopathy in other diseases classified elsewhere (Cervical region)
0.000 0.989 0.011
M49.81 Spondylopathy in other diseases classified elsewhere (Occipito-atlanto-axial region)
0.000 0.989 0.011
M49.80 Spondylopathy in other diseases classified elsewhere (Multiple sites in spine)
0.000 0.989 0.011

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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