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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2395269
log Bayes Factor = 12.7147
Chromosome 6   position 32,817,774  (GRCh37) Explore rs2395269 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E10.9 Without complications
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10.1 With ketoacidosis
0.994 0.006 0.000
E10.3 With ophthalmic complications
0.993 0.007 0.000
E10.4 With neurological complications
0.964 0.036 0.000
E10.5 With peripheral circulatory complications
0.882 0.118 0.000
E10.8 With unspecified complications
0.874 0.126 0.000
E10.0 With coma
0.831 0.168 0.000
E10.2 With renal complications
0.774 0.226 0.000
E10.6 With other specified complications
0.722 0.277 0.000
E10.7 With multiple complications
0.717 0.283 0.000
K90 Intestinal malabsorption
0.000 0.619 0.381
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.687 0.313
K90.3 Pancreatic steatorrhoea
0.000 0.727 0.273
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.727 0.273
K90.1 Tropical sprue
0.000 0.727 0.273
K90.8 Other intestinal malabsorption
0.000 0.764 0.236
K90.9 Intestinal malabsorption, unspecified
0.000 0.780 0.220
E10-E14 Diabetes mellitus
0.135 0.865 0.000
E12 Malnutrition-related diabetes mellitus
0.097 0.903 0.000
E13 Other specified diabetes mellitus
0.086 0.913 0.000
E14 Unspecified diabetes mellitus
0.079 0.921 0.000
E12.9 Without complications
0.070 0.930 0.000
E12.8 With unspecified complications
0.070 0.930 0.000
E12.7 With multiple complications
0.070 0.930 0.000
E12.6 With other specified complications
0.070 0.930 0.000
E12.5 With peripheral circulatory complications
0.070 0.930 0.000
E12.4 With neurological complications
0.070 0.930 0.000
E12.3 With ophthalmic complications
0.070 0.930 0.000
E12.2 With renal complications
0.070 0.930 0.000
E12.1 With ketoacidosis
0.070 0.930 0.000
E12.0 With coma
0.070 0.930 0.000
E14.8 With unspecified complications
0.068 0.932 0.000
E13.8 With unspecified complications
0.062 0.938 0.000
E13.7 With multiple complications
0.062 0.938 0.000
E13.6 With other specified complications
0.062 0.938 0.000
E13.5 With peripheral circulatory complications
0.062 0.938 0.000
E13.4 With neurological complications
0.062 0.938 0.000
E13.3 With ophthalmic complications
0.062 0.938 0.000
E13.2 With renal complications
0.062 0.938 0.000
E13.1 With ketoacidosis
0.062 0.938 0.000
E13.0 With coma
0.062 0.938 0.000
E14.7 With multiple complications
0.057 0.943 0.000
E14.6 With other specified complications
0.057 0.943 0.000
E14.5 With peripheral circulatory complications
0.057 0.943 0.000
E14.2 Withrenal complications
0.057 0.943 0.000
E14.1 With ketoacidosis
0.057 0.943 0.000
E14.0 With coma
0.057 0.943 0.000
E14.4 With neurological complications
0.055 0.945 0.000
E13.9 Without complications
0.051 0.949 0.000
E14.3 With ophthalmic complications
0.051 0.949 0.000
G35 Multiple sclerosis
0.000 0.951 0.049
K90-K93 Other diseases of the digestive system
0.000 0.966 0.034
J06.9 Acute upper respiratory infection, unspecified
0.000 0.972 0.028
E11 Non-insulin-dependent diabetes mellitus
0.026 0.974 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.976 0.024
E11.5 With peripheral circulatory complications
0.023 0.977 0.000
E16.2 Hypoglycaemia, unspecified
0.022 0.978 0.000
E16 Other disorders of pancreatic internal secretion
0.021 0.979 0.000
F33.9 Recurrent depressive disorder, unspecified
0.000 0.979 0.021
E11.1 With ketoacidosis
0.020 0.979 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.020 0.979 0.000
F33 Recurrent depressive disorder
0.000 0.980 0.020
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.020 0.980 0.000
E14.9 Without complications
0.020 0.980 0.000
F31 Bipolar affective disorder
0.000 0.981 0.019
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.000 0.981 0.019
E40-E46 Malnutrition
0.019 0.981 0.000
E11.7 With multiple complications
0.019 0.981 0.000
F31.9 Bipolar affective disorder, unspecified
0.000 0.981 0.019
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.982 0.018
E46 Unspecified protein-energy malnutrition
0.018 0.982 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.982 0.018
K93.1 Megacolon in Chagas' disease
0.000 0.982 0.018
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.982 0.018
L05.9 Pilonidal cyst without abscess
0.018 0.982 0.000
E11.3 With ophthalmic complications
0.018 0.982 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.000 0.983 0.017
E11.0 With coma
0.017 0.983 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.000 0.983 0.017
E11.6 With other specified complications
0.017 0.983 0.000
E11.2 With renal complications
0.016 0.983 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.000 0.983 0.017
F30-F39 Mood [affective] disorders
0.000 0.983 0.016
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.984 0.016
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.000 0.984 0.016
E16.0 Drug-induced hypoglycaemia without coma
0.016 0.984 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.000 0.984 0.016
L05 Pilonidal cyst
0.015 0.985 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.015 0.985 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.015 0.985 0.000
E16.4 Abnormal secretion of gastrin
0.015 0.985 0.000
E16.3 Increased secretion of glucagon
0.015 0.985 0.000
E16.1 Other hypoglycaemia
0.015 0.985 0.000
E11.8 With unspecified complications
0.015 0.985 0.000
F33.8 Other recurrent depressive disorders
0.000 0.985 0.015
F33.4 Recurrent depressive disorder, currently in remission
0.000 0.985 0.015
E15 Nondiabetic hypoglycaemic coma
0.015 0.985 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.000 0.985 0.015
F31.6 Bipolar affective disorder, current episode mixed
0.000 0.986 0.014
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.000 0.986 0.014
F31.8 Other bipolar affective disorders
0.000 0.986 0.014
F31.7 Bipolar affective disorder, currently in remission
0.000 0.986 0.014
E44 Protein-energy malnutrition of moderate and mild degree
0.014 0.986 0.000
E45 Retarded development following protein-energy malnutrition
0.014 0.986 0.000
E43 Unspecified severe protein-energy malnutrition
0.014 0.986 0.000
E42 Marasmic kwashiorkor
0.014 0.986 0.000
E41 Nutritional marasmus
0.014 0.986 0.000
E40 Kwashiorkor
0.014 0.986 0.000
G36 Other acute disseminated demyelination
0.000 0.987 0.013
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.000 0.987 0.013
L05.0 Pilonidal cyst with abscess
0.013 0.987 0.000
F34 Persistent mood [affective] disorders
0.000 0.987 0.013
G37 Other demyelinating diseases of central nervous system
0.000 0.988 0.012
F30 Manic episode
0.000 0.988 0.012
L00-L08 Infections of the skin and subcutaneous tissue
0.012 0.988 0.000
L03.1 Cellulitis of other parts of limb
0.012 0.988 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.000 0.988 0.012
E65-E68 Obesity and other hyperalimentation
0.012 0.988 0.000
F38 Other mood [affective] disorders
0.000 0.988 0.012
J06.8 Other acute upper respiratory infections of multiple sites
0.000 0.988 0.012
J06.0 Acute laryngopharyngitis
0.000 0.988 0.012
L03 Cellulitis
0.012 0.988 0.000
N21.0 Calculus in bladder
0.012 0.988 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.000 0.989 0.011
L03.9 Cellulitis, unspecified
0.011 0.989 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.989 0.010
E65 Localised adiposity
0.010 0.990 0.000
E44.1 Mild protein-energy malnutrition
0.010 0.990 0.000
E44.0 Moderate protein-energy malnutrition
0.010 0.990 0.000
L03.8 Cellulitis of other sites
0.010 0.990 0.000
F34.1 Dysthymia
0.000 0.990 0.010
F30.0 Hypomania
0.000 0.990 0.010
G36.9 Acute disseminated demyelination, unspecified
0.000 0.990 0.010
G36.8 Other specified acute disseminated demyelination
0.000 0.990 0.010
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.990 0.010
G36.0 Neuromyelitis optica [Devic]
0.000 0.990 0.010
F39 Unspecified mood [affective] disorder
0.000 0.990 0.010
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.000 0.990 0.010
L01 Impetigo
0.010 0.990 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.990 0.010
E00-E07 Disorders of thyroid gland
0.006 0.990 0.004
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.010 0.990 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.991 0.009
F34.9 Persistent mood [affective] disorder, unspecified
0.000 0.991 0.009
F34.8 Other persistent mood [affective] disorders
0.000 0.991 0.009
F34.0 Cyclothymia
0.000 0.991 0.009
E11.4 With neurological complications
0.009 0.991 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.009 0.991 0.000
G37.5 Concentric sclerosis [Balo]
0.000 0.991 0.009
G37.4 Subacute necrotising myelitis
0.000 0.991 0.009
G37.2 Central pontine myelinolysis
0.000 0.991 0.009
G37.1 Central demyelination of corpus callosum
0.000 0.991 0.009
G37.0 Diffuse sclerosis
0.000 0.991 0.009
F30.8 Other manic episodes
0.000 0.991 0.009
F30.1 Mania without psychotic symptoms
0.000 0.991 0.009
L08 Other local infections of skin and subcutaneous tissue
0.009 0.991 0.000
L04 Acute lymphadenitis
0.009 0.991 0.000
L00 Staphylococcal scalded skin syndrome
0.009 0.991 0.000
F30.2 Mania with psychotic symptoms
0.000 0.991 0.009
F38.8 Other specified mood [affective] disorders
0.000 0.991 0.009
F38.1 Other recurrent mood [affective] disorders
0.000 0.991 0.009
F38.0 Other single mood [affective] disorders
0.000 0.991 0.009
E67 Other hyperalimentation
0.009 0.991 0.000
E68 Sequelae of hyperalimentation
0.009 0.991 0.000
F30.9 Manic episode, unspecified
0.000 0.991 0.008
E50-E64 Other nutritional deficiencies
0.008 0.991 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.991 0.008
N21 Calculus of lower urinary tract
0.008 0.991 0.000
J02.9 Acute pharyngitis, unspecified
0.000 0.992 0.008
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.000 0.992 0.008
E05.9 Thyrotoxicosis, unspecified
0.000 0.992 0.008
J02 Acute pharyngitis
0.000 0.992 0.008
J00-J06 Acute upper respiratory infections
0.000 0.992 0.008
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.008 0.992 0.000
N21.1 Calculus in urethra
0.008 0.992 0.000
L01.0 Impetigo [any organism] [any site]
0.008 0.992 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.992 0.008
L08.8 Other specified local infections of skin and subcutaneous tissue
0.008 0.992 0.000
E20-E35 Disorders of other endocrine glands
0.008 0.992 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.992 0.008
E03 Other hypothyroidism
0.001 0.992 0.006
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.007 0.993 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.007 0.993 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.001 0.993 0.007
L01.1 Impetiginisation of other dermatoses
0.007 0.993 0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.000 0.993 0.007
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.000 0.993 0.007
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.000 0.993 0.007
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.000 0.993 0.007
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.000 0.993 0.007
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.000 0.993 0.007
L03.3 Cellulitis of trunk
0.007 0.993 0.000
K92 Other diseases of digestive system
0.000 0.993 0.007
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.004 0.993 0.003
E00 Congenital iodine-deficiency syndrome
0.004 0.993 0.003
E02 Subclinical iodine-deficiency hypothyroidism
0.004 0.993 0.003
E22 Hyperfunction of pituitary gland
0.007 0.993 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.993 0.007
K22.7 Barrett's oesophagus
0.000 0.993 0.007
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.007 0.993 0.000
H36.0 Diabetic retinopathy
0.007 0.993 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.007 0.993 0.000
K91.1 Postgastric surgery syndromes
0.000 0.993 0.007
E22.0 Acromegaly and pituitary gigantism
0.007 0.993 0.000
L08.1 Erythrasma
0.007 0.993 0.000
L08.0 Pyoderma
0.007 0.993 0.000
L04.9 Acute lymphadenitis, unspecified
0.007 0.993 0.000
L04.8 Acute lymphadenitis of other sites
0.007 0.993 0.000
L04.3 Acute lymphadenitis of lower limb
0.007 0.993 0.000
L04.2 Acute lymphadenitis of upper limb
0.007 0.993 0.000
L04.1 Acute lymphadenitis of trunk
0.007 0.993 0.000
L04.0 Acute lymphadenitis of face, head and neck
0.007 0.993 0.000
E67.8 Other specified hyperalimentation
0.006 0.993 0.000
E67.3 Hypervitaminosis D
0.006 0.993 0.000
E67.2 Megavitamin-B6 syndrome
0.006 0.993 0.000
E67.1 Hypercarotenaemia
0.006 0.993 0.000
E67.0 Hypervitaminosis A
0.006 0.993 0.000
E24 Cushing's syndrome
0.007 0.993 0.000
J04 Acute laryngitis and tracheitis
0.000 0.993 0.007
E26 Hyperaldosteronism
0.006 0.993 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.006 0.994 0.000
E63 Other nutritional deficiencies
0.006 0.994 0.000
E56 Other vitamin deficiencies
0.006 0.994 0.000
E51 Thiamine deficiency
0.006 0.994 0.000
E50 Vitamin A deficiency
0.006 0.994 0.000
E60 Dietary zinc deficiency
0.006 0.994 0.000
E59 Dietary selenium deficiency
0.006 0.994 0.000
E58 Dietary calcium deficiency
0.006 0.994 0.000
E54 Ascorbic acid deficiency
0.006 0.994 0.000
E52 Niacin deficiency [pellagra]
0.006 0.994 0.000
K91.5 Postcholecystectomy syndrome
0.000 0.994 0.006
N21.9 Calculus of lower urinary tract, unspecified
0.006 0.994 0.000
N21.8 Other lower urinary tract calculus
0.006 0.994 0.000
E07 Other disorders of thyroid
0.004 0.994 0.002
E25 Adrenogenital disorders
0.006 0.994 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.994 0.006
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.994 0.006
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.000 0.994 0.006
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.994 0.006
Z36.9 Antenatal screening, unspecified
0.006 0.994 0.000
E06 Thyroiditis
0.003 0.994 0.003
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.994 0.006
J02.0 Streptococcal pharyngitis
0.000 0.994 0.006
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.006 0.994 0.000
E22.1 Hyperprolactinaemia
0.006 0.994 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.994 0.006
E61 Deficiency of other nutrient elements
0.006 0.994 0.000
E03.8 Other specified hypothyroidism
0.001 0.994 0.005
J01 Acute sinusitis
0.000 0.994 0.006
K92.8 Other specified diseases of digestive system
0.000 0.994 0.006
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.006 0.994 0.000
E26.0 Primary hyperaldosteronism
0.006 0.994 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.006 0.994 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.006 0.994 0.000
E32 Diseases of thymus
0.006 0.994 0.000
E31 Polyglandular dysfunction
0.006 0.994 0.000
E30 Disorders of puberty, not elsewhere classified
0.006 0.994 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.006 0.994 0.000
E03.5 Myxoedema coma
0.001 0.994 0.005
E03.4 Atrophy of thyroid (acquired)
0.001 0.994 0.005
E03.3 Postinfectious hypothyroidism
0.001 0.994 0.005
E03.1 Congenital hypothyroidism without goitre
0.001 0.994 0.005
E03.0 Congenital hypothyroidism with diffuse goitre
0.001 0.994 0.005
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.001 0.994 0.005
E05.8 Other thyrotoxicosis
0.001 0.994 0.005
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.000 0.994 0.005
L03.2 Cellulitis of face
0.006 0.994 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.994 0.005
E05.5 Thyroid crisis or storm
0.001 0.994 0.005
E05.4 Thyrotoxicosis factitia
0.001 0.994 0.005
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.001 0.994 0.005
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.001 0.994 0.005
E24.2 Drug-induced Cushing's syndrome
0.005 0.995 0.000
K91.3 Postoperative intestinal obstruction
0.000 0.995 0.005
J04.0 Acute laryngitis
0.000 0.995 0.005
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.005 0.995 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.003 0.995 0.002
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.003 0.995 0.002
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.003 0.995 0.002
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.003 0.995 0.002
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.003 0.995 0.002
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.003 0.995 0.002
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.003 0.995 0.002
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.003 0.995 0.002
E04 Other non-toxic goitre
0.005 0.995 0.000
E24.0 Pituitary-dependent Cushing's disease
0.005 0.995 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.005 0.995 0.000
E22.8 Other hyperfunction of pituitary gland
0.005 0.995 0.000
E24.9 Cushing's syndrome, unspecified
0.005 0.995 0.000
J04.1 Acute tracheitis
0.000 0.995 0.005
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.005 0.995 0.000
E20 Hypoparathyroidism
0.005 0.995 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.005 0.995 0.000
E24.8 Other Cushing's syndrome
0.005 0.995 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.005 0.995 0.000
E24.3 Ectopic ACTH syndrome
0.005 0.995 0.000
E24.1 Nelson's syndrome
0.005 0.995 0.000
J04.2 Acute laryngotracheitis
0.000 0.995 0.005
E26.9 Hyperaldosteronism, unspecified
0.005 0.995 0.000
E26.8 Other hyperaldosteronism
0.005 0.995 0.000
E26.1 Secondary hyperaldosteronism
0.005 0.995 0.000
E07.8 Other specified disorders of thyroid
0.004 0.995 0.001
E50.9 Vitamin A deficiency, unspecified
0.005 0.995 0.000
E50.8 Other manifestations of vitamin A deficiency
0.005 0.995 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.005 0.995 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.005 0.995 0.000
E50.5 Vitamin A deficiency with night blindness
0.005 0.995 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.005 0.995 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.005 0.995 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.005 0.995 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.005 0.995 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.005 0.995 0.000
E51.9 Thiamine deficiency, unspecified
0.005 0.995 0.000
E51.8 Other manifestations of thiamine deficiency
0.005 0.995 0.000
E51.2 Wernicke's encephalopathy
0.005 0.995 0.000
E51.1 Beriberi
0.005 0.995 0.000
E56.9 Vitamin deficiency, unspecified
0.005 0.995 0.000
E56.8 Deficiency of other vitamins
0.005 0.995 0.000
E56.1 Deficiency of vitamin K
0.005 0.995 0.000
E56.0 Deficiency of vitamin E
0.005 0.995 0.000
E63.9 Nutritional deficiency, unspecified
0.005 0.995 0.000
E63.8 Other specified nutritional deficiencies
0.005 0.995 0.000
E63.1 Imbalance of constituents of food intake
0.005 0.995 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.005 0.995 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.005 0.995 0.000
E64.8 Sequelae of other nutritional deficiencies
0.005 0.995 0.000
E64.3 Sequelae of rickets
0.005 0.995 0.000
E64.2 Sequelae of vitamin C deficiency
0.005 0.995 0.000
E64.1 Sequelae of vitamin A deficiency
0.005 0.995 0.000
E64.0 Sequelae of protein-energy malnutrition
0.005 0.995 0.000
F32 Depressive episode
0.000 0.995 0.005
E55 Vitamin D deficiency
0.004 0.995 0.001
E07.1 Dyshormogenetic goitre
0.003 0.995 0.002
E07.0 Hypersecretion of calcitonin
0.003 0.995 0.002
E25.9 Adrenogenital disorder, unspecified
0.005 0.995 0.000
E25.8 Other adrenogenital disorders
0.005 0.995 0.000
J05.1 Acute epiglottitis
0.000 0.995 0.005
R40.0 Somnolence
0.005 0.995 0.000
J03 Acute tonsillitis
0.000 0.995 0.005
J05.0 Acute obstructive laryngitis [croup]
0.000 0.995 0.004
L03.0 Cellulitis of finger and toe
0.005 0.995 0.000
E28 Ovarian dysfunction
0.004 0.995 0.000
E06.5 Other chronic thyroiditis
0.002 0.995 0.002
E06.4 Drug-induced thyroiditis
0.002 0.995 0.002
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.002 0.995 0.002
E06.1 Subacute thyroiditis
0.002 0.995 0.002
E06.0 Acute thyroiditis
0.002 0.995 0.002
E53 Deficiency of other B group vitamins
0.004 0.995 0.000
E61.9 Deficiency of nutrient element, unspecified
0.004 0.995 0.000
E61.8 Deficiency of other specified nutrient elements
0.004 0.995 0.000
E61.7 Deficiency of multiple nutrient elements
0.004 0.995 0.000
E61.6 Vanadium deficiency
0.004 0.995 0.000
E61.5 Molybdenum deficiency
0.004 0.995 0.000
E61.4 Chromium deficiency
0.004 0.995 0.000
E61.3 Manganese deficiency
0.004 0.995 0.000
E61.2 Magnesium deficiency
0.004 0.995 0.000
E61.0 Copper deficiency
0.004 0.995 0.000
E04.9 Non-toxic goitre, unspecified
0.004 0.995 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.004 0.995 0.000
E29 Testicular dysfunction
0.004 0.995 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.004 0.995 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.001 0.995 0.004
J01.8 Other acute sinusitis
0.000 0.996 0.004
J01.4 Acute pansinusitis
0.000 0.996 0.004
J01.3 Acute sphenoidal sinusitis
0.000 0.996 0.004
J01.2 Acute ethmoidal sinusitis
0.000 0.996 0.004
J01.1 Acute frontal sinusitis
0.000 0.996 0.004
K83.8 Other specified diseases of biliary tract
0.000 0.996 0.004
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.004 0.996 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.004 0.996 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.004 0.996 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.004 0.996 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.004 0.996 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.004 0.996 0.000
T44.0 Anticholinesterase agents
0.004 0.996 0.000
E30.9 Disorder of puberty, unspecified
0.004 0.996 0.000
E30.8 Other disorders of puberty
0.004 0.996 0.000
E30.1 Precocious puberty
0.004 0.996 0.000
E30.0 Delayed puberty
0.004 0.996 0.000
E31.9 Polyglandular dysfunction, unspecified
0.004 0.996 0.000
E31.8 Other polyglandular dysfunction
0.004 0.996 0.000
E31.1 Polyglandular hyperfunction
0.004 0.996 0.000
E31.0 Autoimmune polyglandular failure
0.004 0.996 0.000
E32.9 Disease of thymus, unspecified
0.004 0.996 0.000
E32.8 Other diseases of thymus
0.004 0.996 0.000
E32.1 Abscess of thymus
0.004 0.996 0.000
E32.0 Persistent hyperplasia of thymus
0.004 0.996 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.004 0.996 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.004 0.996 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.004 0.996 0.000
E06.9 Thyroiditis, unspecified
0.002 0.996 0.002
J01.9 Acute sinusitis, unspecified
0.000 0.996 0.004
J01.0 Acute maxillary sinusitis
0.000 0.996 0.004
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.004 0.996 0.000
E04.1 Non-toxic single thyroid nodule
0.004 0.996 0.000
K91.4 Colostomy and enterostomy malfunction
0.000 0.996 0.004
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.004 0.996 0.000
E04.8 Other specified non-toxic goitre
0.004 0.996 0.000
E27 Other disorders of adrenal gland
0.004 0.996 0.000
M46 Other inflammatory spondylopathies
0.000 0.996 0.004
F32.0 Mild depressive episode
0.000 0.996 0.004
E04.0 Non-toxic diffuse goitre
0.004 0.996 0.000
R47.0 Dysphasia and aphasia
0.004 0.996 0.000
E61.1 Iron deficiency
0.004 0.996 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.004 0.996 0.000
D12.4 Descending colon
0.000 0.996 0.004
E04.2 Non-toxic multinodular goitre
0.004 0.996 0.000
E20.8 Other hypoparathyroidism
0.004 0.996 0.000
E20.1 Pseudohypoparathyroidism
0.004 0.996 0.000
E20.0 Idiopathic hypoparathyroidism
0.004 0.996 0.000
K92.1 Melaena
0.000 0.996 0.004
Z36 Antenatal screening
0.004 0.996 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.004 0.996 0.000
E06.3 Autoimmune thyroiditis
0.002 0.996 0.002
E34 Other endocrine disorders
0.003 0.996 0.001
K92.9 Disease of digestive system, unspecified
0.000 0.996 0.004
E55.0 Rickets, active
0.003 0.996 0.001
E28.3 Primary ovarian failure
0.003 0.996 0.000
J03.8 Acute tonsillitis due to other specified organisms
0.000 0.996 0.004
J03.0 Streptococcal tonsillitis
0.000 0.996 0.004
M45.X9 Ankylosing spondylitis (Site unspecified)
0.004 0.996 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.004 0.996 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.000 0.996 0.004
N64.1 Fat necrosis of breast
0.000 0.996 0.004
M25.56 Pain in joint (Lower leg)
0.004 0.996 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.004 0.996 0.000
K92.0 Haematemesis
0.000 0.996 0.004
E28.9 Ovarian dysfunction, unspecified
0.003 0.996 0.000
E28.8 Other ovarian dysfunction
0.003 0.996 0.000
E28.1 Androgen excess
0.003 0.996 0.000
E28.0 Oestrogen excess
0.003 0.996 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.000 0.996 0.004
Z36.8 Other antenatal screening
0.004 0.996 0.000
E53.1 Pyridoxine deficiency
0.003 0.996 0.000
E53.0 Riboflavin deficiency
0.003 0.996 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.004 0.996 0.000
E29.9 Testicular dysfunction, unspecified
0.003 0.996 0.000
E29.8 Other testicular dysfunction
0.003 0.996 0.000
E29.0 Testicular hyperfunction
0.003 0.996 0.000
M25.51 Pain in joint (Shoulder region)
0.004 0.996 0.000
Z87.0 Personal history of diseases of the respiratory system
0.004 0.996 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.003 0.997 0.000
E07.9 Disorder of thyroid, unspecified
0.002 0.997 0.002
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.003 0.997 0.000
M65.34 Trigger finger-Hand
0.000 0.997 0.003
E27.8 Other specified disorders of adrenal gland
0.003 0.997 0.000
Z37.2 Twins, both liveborn
0.003 0.997 0.000
J33.0 Polyp of nasal cavity
0.003 0.997 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.000 0.997 0.003
E21.4 Other specified disorders of parathyroid gland
0.003 0.997 0.000
E21.2 Other hyperparathyroidism
0.003 0.997 0.000
E27.9 Disorder of adrenal gland, unspecified
0.003 0.997 0.000
E27.2 Addisonian crisis
0.003 0.997 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.003 0.997 0.000
E20.9 Hypoparathyroidism, unspecified
0.003 0.997 0.000
F32.8 Other depressive episodes
0.000 0.997 0.003
E27.5 Adrenomedullary hyperfunction
0.003 0.997 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.003 0.997 0.000
E27.0 Other adrenocortical overactivity
0.003 0.997 0.000
E23 Hypofunction and other disorders of pituitary gland
0.003 0.997 0.000
M46.8 Other specified inflammatory spondylopathies
0.000 0.997 0.003
M46.5 Other infective spondylopathies
0.000 0.997 0.003
M46.3 Infection of intervertebral disk (pyogenic)
0.000 0.997 0.003
M46.2 Osteomyelitis of vertebra
0.000 0.997 0.003
M46.1 Sacro-iliitis, not elsewhere classified
0.000 0.997 0.003
M46.0 Spinal enthesopathy
0.000 0.997 0.003
Z36.2 Other antenatal screening based on amniocentesis
0.003 0.997 0.000
M54.4 Lumbago with sciatica
0.003 0.997 0.000
E53.9 Vitamin B deficiency, unspecified
0.003 0.997 0.000
M25.78 Osteophyte (Other)
0.003 0.997 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.003 0.997 0.000
K86.1 Other chronic pancreatitis
0.003 0.997 0.000
M46.4 Discitis, unspecified
0.000 0.997 0.003
Z36.5 Antenatal screening for isoimmunisation
0.003 0.997 0.000
E34.5 Androgen resistance syndrome
0.002 0.997 0.001
E34.4 Constitutional tall stature
0.002 0.997 0.001
E34.3 Short stature, not elsewhere classified
0.002 0.997 0.001
E34.2 Ectopic hormone secretion, not elsewhere classified
0.002 0.997 0.001
E34.1 Other hypersecretion of intestinal hormones
0.002 0.997 0.001
K01.1 Impacted teeth
0.000 0.997 0.003
H36 Retinal disorders in diseases classified elsewhere
0.003 0.997 0.000
H50.9 Strabismus, unspecified
0.000 0.997 0.003
M25.71 Osteophyte (Shoulder region)
0.003 0.997 0.000
C79 Secondary malignant neoplasm of other sites
0.003 0.997 0.000
C79.6 Secondary malignant neoplasm of ovary
0.003 0.997 0.000
M25.7 Osteophyte
0.003 0.997 0.000
D12.5 Sigmoid colon
0.000 0.997 0.003
N85.9 Noninflammatory disorder of uterus, unspecified
0.003 0.997 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.003 0.997 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.003 0.997 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.003 0.997 0.000
M86.9 Osteomyelitis, unspecified
0.003 0.997 0.000
M25.72 Osteophyte (Upper arm)
0.003 0.997 0.000
E34.0 Carcinoid syndrome
0.002 0.997 0.001
N73.6 Female pelvic peritoneal adhesions
0.000 0.997 0.003
E34.8 Other specified endocrine disorders
0.002 0.997 0.001
F32.1 Moderate depressive episode
0.000 0.997 0.003
G51.0 Bell's palsy
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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