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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2395296
log Bayes Factor = 50.4198
Chromosome 6   position 32,911,814  (GRCh37) Explore rs2395296 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.999 0.001 0.000
E10.1 With ketoacidosis
0.000 0.012 0.988
L40 Psoriasis
0.986 0.014 0.000
L40.5 Arthropathic psoriasis
0.984 0.016 0.000
E10.4 With neurological complications
0.000 0.027 0.973
E10-E14 Diabetes mellitus
0.000 0.060 0.940
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.064 0.936
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.065 0.935
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.067 0.933
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.071 0.929
E16 Other disorders of pancreatic internal secretion
0.000 0.073 0.927
E05.9 Thyrotoxicosis, unspecified
0.000 0.075 0.925
E16.2 Hypoglycaemia, unspecified
0.000 0.077 0.923
E00-E07 Disorders of thyroid gland
0.000 0.080 0.920
E10.2 With renal complications
0.000 0.110 0.890
E40-E46 Malnutrition
0.000 0.122 0.878
L40.8 Other psoriasis
0.848 0.152 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.161 0.839
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.170 0.830
E10.5 With peripheral circulatory complications
0.000 0.209 0.791
K90 Intestinal malabsorption
0.000 0.258 0.742
E10.7 With multiple complications
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.289 0.711
L40.4 Guttate psoriasis
0.707 0.293 0.000
L40.2 Acrodermatitis continua
0.707 0.293 0.000
E10.8 With unspecified complications
0.000 0.304 0.696
E13 Other specified diabetes mellitus
0.000 0.320 0.680
L40.1 Generalised pustular psoriasis
0.676 0.323 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.326 0.674
E05.5 Thyroid crisis or storm
0.000 0.329 0.671
E05.4 Thyrotoxicosis factitia
0.000 0.329 0.671
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.329 0.671
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.329 0.671
E15 Nondiabetic hypoglycaemic coma
0.000 0.334 0.666
E10.0 With coma
0.000 0.334 0.666
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.335 0.665
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.335 0.665
E16.4 Abnormal secretion of gastrin
0.000 0.335 0.665
E16.3 Increased secretion of glucagon
0.000 0.335 0.665
K90.9 Intestinal malabsorption, unspecified
0.000 0.337 0.663
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.340 0.660
E00 Congenital iodine-deficiency syndrome
0.000 0.340 0.660
L40.3 Pustulosis palmaris et plantaris
0.648 0.351 0.000
E10.6 With other specified complications
0.000 0.359 0.641
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.370 0.630
E45 Retarded development following protein-energy malnutrition
0.000 0.370 0.630
E43 Unspecified severe protein-energy malnutrition
0.000 0.370 0.630
E42 Marasmic kwashiorkor
0.000 0.370 0.630
E41 Nutritional marasmus
0.000 0.370 0.630
E40 Kwashiorkor
0.000 0.370 0.630
E16.1 Other hypoglycaemia
0.000 0.396 0.604
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.401 0.599
E65-E68 Obesity and other hyperalimentation
0.000 0.412 0.588
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.412 0.588
K90.3 Pancreatic steatorrhoea
0.000 0.468 0.532
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.468 0.532
K90.1 Tropical sprue
0.000 0.468 0.532
E13.9 Without complications
0.000 0.476 0.524
K90.8 Other intestinal malabsorption
0.000 0.477 0.523
E65 Localised adiposity
0.000 0.493 0.507
E13.8 With unspecified complications
0.000 0.513 0.487
E13.7 With multiple complications
0.000 0.513 0.487
E13.6 With other specified complications
0.000 0.513 0.487
E13.5 With peripheral circulatory complications
0.000 0.513 0.487
E13.4 With neurological complications
0.000 0.513 0.487
E13.2 With renal complications
0.000 0.513 0.487
E13.1 With ketoacidosis
0.000 0.513 0.487
E13.0 With coma
0.000 0.513 0.487
E12.9 Without complications
0.000 0.516 0.483
E12.8 With unspecified complications
0.000 0.516 0.483
E12.7 With multiple complications
0.000 0.516 0.483
E12.6 With other specified complications
0.000 0.516 0.483
E12.5 With peripheral circulatory complications
0.000 0.516 0.483
E12.4 With neurological complications
0.000 0.516 0.483
E12.3 With ophthalmic complications
0.000 0.516 0.483
E12.2 With renal complications
0.000 0.516 0.483
E12.1 With ketoacidosis
0.000 0.516 0.483
E12.0 With coma
0.000 0.516 0.483
E07 Other disorders of thyroid
0.000 0.521 0.478
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.527 0.473
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.527 0.473
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.527 0.473
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.527 0.473
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.527 0.473
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.527 0.473
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.527 0.473
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.527 0.473
E14 Unspecified diabetes mellitus
0.000 0.547 0.453
E44.1 Mild protein-energy malnutrition
0.000 0.548 0.452
E44.0 Moderate protein-energy malnutrition
0.000 0.548 0.452
E13.3 With ophthalmic complications
0.000 0.551 0.449
E67 Other hyperalimentation
0.000 0.578 0.422
E68 Sequelae of hyperalimentation
0.000 0.578 0.422
L40.0 Psoriasis vulgaris
0.415 0.585 0.000
E14.3 With ophthalmic complications
0.000 0.602 0.398
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.604 0.396
E14.8 With unspecified complications
0.000 0.638 0.362
E06 Thyroiditis
0.000 0.639 0.361
L40-L45 Papulosquamous disorders
0.344 0.656 0.000
E07.1 Dyshormogenetic goitre
0.000 0.657 0.343
E07.0 Hypersecretion of calcitonin
0.000 0.657 0.343
E14.7 With multiple complications
0.000 0.675 0.325
E14.0 With coma
0.000 0.675 0.325
E07.9 Disorder of thyroid, unspecified
0.000 0.677 0.323
E14.6 With other specified complications
0.000 0.693 0.307
E03 Other hypothyroidism
0.000 0.694 0.306
E67.8 Other specified hyperalimentation
0.000 0.697 0.302
E67.3 Hypervitaminosis D
0.000 0.697 0.302
E67.2 Megavitamin-B6 syndrome
0.000 0.697 0.302
E67.1 Hypercarotenaemia
0.000 0.697 0.302
E67.0 Hypervitaminosis A
0.000 0.697 0.302
E14.1 With ketoacidosis
0.000 0.703 0.297
E14.4 With neurological complications
0.000 0.704 0.295
E14.2 Withrenal complications
0.000 0.705 0.295
E14.5 With peripheral circulatory complications
0.000 0.710 0.290
E50-E64 Other nutritional deficiencies
0.000 0.721 0.278
L42 Pityriasis rosea
0.275 0.725 0.000
E06.4 Drug-induced thyroiditis
0.000 0.741 0.259
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.741 0.259
E06.1 Subacute thyroiditis
0.000 0.741 0.259
E06.0 Acute thyroiditis
0.000 0.741 0.259
E03.8 Other specified hypothyroidism
0.000 0.741 0.259
E06.5 Other chronic thyroiditis
0.000 0.748 0.252
L44 Other papulosquamous disorders
0.247 0.753 0.000
L41 Parapsoriasis
0.247 0.753 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.247 0.753 0.000
E03.5 Myxoedema coma
0.000 0.780 0.220
E03.4 Atrophy of thyroid (acquired)
0.000 0.780 0.220
E03.3 Postinfectious hypothyroidism
0.000 0.780 0.220
E07.8 Other specified disorders of thyroid
0.001 0.797 0.203
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.798 0.202
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.800 0.200
E63 Other nutritional deficiencies
0.000 0.800 0.200
E50 Vitamin A deficiency
0.000 0.800 0.200
E60 Dietary zinc deficiency
0.000 0.800 0.200
E59 Dietary selenium deficiency
0.000 0.800 0.200
E58 Dietary calcium deficiency
0.000 0.800 0.200
E54 Ascorbic acid deficiency
0.000 0.800 0.200
E52 Niacin deficiency [pellagra]
0.000 0.800 0.200
E56 Other vitamin deficiencies
0.000 0.809 0.190
E03.1 Congenital hypothyroidism without goitre
0.000 0.810 0.189
E06.9 Thyroiditis, unspecified
0.001 0.812 0.187
E51 Thiamine deficiency
0.000 0.820 0.180
E61 Deficiency of other nutrient elements
0.000 0.821 0.179
L41.9 Parapsoriasis, unspecified
0.177 0.823 0.000
L41.8 Other parapsoriasis
0.177 0.823 0.000
L41.5 Retiform parapsoriasis
0.177 0.823 0.000
L41.4 Large plaque parapsoriasis
0.177 0.823 0.000
L41.3 Small plaque parapsoriasis
0.177 0.823 0.000
L41.2 Lymphomatoid papulosis
0.177 0.823 0.000
L41.1 Pityriasis lichenoides chronica
0.177 0.823 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.177 0.823 0.000
L44.9 Papulosquamous disorder, unspecified
0.177 0.823 0.000
L44.8 Other specified papulosquamous disorders
0.177 0.823 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.177 0.823 0.000
L44.3 Lichen ruber moniliformis
0.177 0.823 0.000
L44.2 Lichen striatus
0.177 0.823 0.000
L44.1 Lichen nitidus
0.177 0.823 0.000
L44.0 Pityriasis rubra pilaris
0.177 0.823 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.835 0.165
L43 Lichen planus
0.160 0.840 0.000
E55 Vitamin D deficiency
0.000 0.842 0.158
E20-E35 Disorders of other endocrine glands
0.000 0.847 0.153
R06.8 Other and unspecified abnormalities of breathing
0.145 0.855 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.856 0.143
E50.8 Other manifestations of vitamin A deficiency
0.000 0.856 0.143
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.856 0.143
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.856 0.143
E50.5 Vitamin A deficiency with night blindness
0.000 0.856 0.143
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.856 0.143
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.856 0.143
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.856 0.143
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.856 0.143
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.856 0.143
E63.9 Nutritional deficiency, unspecified
0.000 0.856 0.143
E63.8 Other specified nutritional deficiencies
0.000 0.856 0.143
E63.1 Imbalance of constituents of food intake
0.000 0.856 0.143
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.856 0.143
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.856 0.143
E64.8 Sequelae of other nutritional deficiencies
0.000 0.856 0.143
E64.3 Sequelae of rickets
0.000 0.856 0.143
E64.2 Sequelae of vitamin C deficiency
0.000 0.856 0.143
E64.1 Sequelae of vitamin A deficiency
0.000 0.856 0.143
E64.0 Sequelae of protein-energy malnutrition
0.000 0.856 0.143
E06.3 Autoimmune thyroiditis
0.000 0.859 0.141
E56.9 Vitamin deficiency, unspecified
0.000 0.863 0.137
E56.8 Deficiency of other vitamins
0.000 0.863 0.137
E56.0 Deficiency of vitamin E
0.000 0.863 0.137
E22 Hyperfunction of pituitary gland
0.000 0.864 0.136
E51.9 Thiamine deficiency, unspecified
0.000 0.871 0.129
E51.8 Other manifestations of thiamine deficiency
0.000 0.871 0.129
E51.1 Beriberi
0.000 0.871 0.129
E61.9 Deficiency of nutrient element, unspecified
0.000 0.871 0.128
E61.8 Deficiency of other specified nutrient elements
0.000 0.871 0.128
E61.7 Deficiency of multiple nutrient elements
0.000 0.871 0.128
E61.6 Vanadium deficiency
0.000 0.871 0.128
E61.5 Molybdenum deficiency
0.000 0.871 0.128
E61.4 Chromium deficiency
0.000 0.871 0.128
E61.3 Manganese deficiency
0.000 0.871 0.128
E61.0 Copper deficiency
0.000 0.871 0.128
E56.1 Deficiency of vitamin K
0.000 0.872 0.127
E61.2 Magnesium deficiency
0.000 0.874 0.125
E26 Hyperaldosteronism
0.000 0.877 0.123
E11 Non-insulin-dependent diabetes mellitus
0.000 0.877 0.123
E22.1 Hyperprolactinaemia
0.000 0.879 0.121
E11.5 With peripheral circulatory complications
0.000 0.881 0.119
L43.3 Subacute (active) lichen planus
0.115 0.885 0.000
L43.2 Lichenoid drug reaction
0.115 0.885 0.000
L43.1 Bullous lichen planus
0.115 0.885 0.000
L43.0 Hypertrophic lichen planus
0.115 0.885 0.000
E83.1 Disorders of iron metabolism
0.114 0.886 0.000
E55.0 Rickets, active
0.000 0.886 0.113
E61.1 Iron deficiency
0.000 0.889 0.111
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.889 0.111
E34 Other endocrine disorders
0.000 0.890 0.110
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.890 0.110
E32 Diseases of thymus
0.000 0.890 0.110
E30 Disorders of puberty, not elsewhere classified
0.000 0.890 0.110
E51.2 Wernicke's encephalopathy
0.001 0.891 0.109
E25 Adrenogenital disorders
0.000 0.892 0.108
L43.8 Other lichen planus
0.107 0.893 0.000
E53 Deficiency of other B group vitamins
0.001 0.894 0.106
E29 Testicular dysfunction
0.000 0.898 0.102
E31 Polyglandular dysfunction
0.000 0.902 0.098
E26.0 Primary hyperaldosteronism
0.000 0.902 0.098
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.902 0.097
E22.8 Other hyperfunction of pituitary gland
0.000 0.902 0.097
E26.9 Hyperaldosteronism, unspecified
0.000 0.906 0.094
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.906 0.094
E34.8 Other specified endocrine disorders
0.000 0.907 0.093
E24 Cushing's syndrome
0.000 0.911 0.089
E26.8 Other hyperaldosteronism
0.000 0.911 0.088
E26.1 Secondary hyperaldosteronism
0.000 0.911 0.088
E11.7 With multiple complications
0.000 0.912 0.088
E22.0 Acromegaly and pituitary gigantism
0.000 0.913 0.087
E23 Hypofunction and other disorders of pituitary gland
0.000 0.914 0.086
E11.2 With renal complications
0.000 0.915 0.084
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.918 0.082
E11.8 With unspecified complications
0.000 0.918 0.082
E34.5 Androgen resistance syndrome
0.000 0.921 0.079
E34.4 Constitutional tall stature
0.000 0.921 0.079
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.921 0.079
E34.1 Other hypersecretion of intestinal hormones
0.000 0.921 0.079
E34.0 Carcinoid syndrome
0.000 0.921 0.079
E30.9 Disorder of puberty, unspecified
0.000 0.921 0.079
E30.8 Other disorders of puberty
0.000 0.921 0.079
E30.1 Precocious puberty
0.000 0.921 0.079
E30.0 Delayed puberty
0.000 0.921 0.079
E32.9 Disease of thymus, unspecified
0.000 0.921 0.079
E32.8 Other diseases of thymus
0.000 0.921 0.079
E32.1 Abscess of thymus
0.000 0.921 0.079
E32.0 Persistent hyperplasia of thymus
0.000 0.921 0.079
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.921 0.079
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.921 0.079
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.921 0.079
E66 Obesity
0.000 0.921 0.079
E25.9 Adrenogenital disorder, unspecified
0.000 0.922 0.078
E25.8 Other adrenogenital disorders
0.000 0.922 0.078
E53.1 Pyridoxine deficiency
0.001 0.923 0.076
E53.0 Riboflavin deficiency
0.001 0.923 0.076
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.924 0.076
E34.3 Short stature, not elsewhere classified
0.000 0.925 0.075
E29.9 Testicular dysfunction, unspecified
0.000 0.926 0.073
E29.8 Other testicular dysfunction
0.000 0.926 0.073
E29.0 Testicular hyperfunction
0.000 0.926 0.073
E55.9 Vitamin D deficiency, unspecified
0.000 0.928 0.072
E20 Hypoparathyroidism
0.001 0.928 0.071
E31.9 Polyglandular dysfunction, unspecified
0.000 0.929 0.070
E31.8 Other polyglandular dysfunction
0.000 0.929 0.070
E31.1 Polyglandular hyperfunction
0.000 0.929 0.070
E21.2 Other hyperparathyroidism
0.000 0.930 0.069
E53.9 Vitamin B deficiency, unspecified
0.001 0.931 0.069
E11.6 With other specified complications
0.000 0.931 0.069
E21.4 Other specified disorders of parathyroid gland
0.000 0.932 0.068
E29.1 Testicular hypofunction
0.000 0.934 0.066
E24.0 Pituitary-dependent Cushing's disease
0.000 0.935 0.065
E24.8 Other Cushing's syndrome
0.000 0.936 0.064
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.936 0.064
E24.3 Ectopic ACTH syndrome
0.000 0.936 0.064
E24.1 Nelson's syndrome
0.000 0.936 0.064
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.938 0.062
E23.1 Drug-induced hypopituitarism
0.000 0.938 0.062
E83 Disorders of mineral metabolism
0.062 0.938 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.939 0.061
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.939 0.060
E23.7 Disorder of pituitary gland, unspecified
0.000 0.940 0.060
E34.9 Endocrine disorder, unspecified
0.000 0.940 0.060
E28 Ovarian dysfunction
0.001 0.941 0.059
E23.2 Diabetes insipidus
0.000 0.941 0.059
E31.0 Autoimmune polyglandular failure
0.000 0.941 0.058
E11.0 With coma
0.000 0.942 0.058
E21.0 Primary hyperparathyroidism
0.000 0.942 0.058
E04 Other non-toxic goitre
0.000 0.942 0.057
E66.1 Drug-induced obesity
0.000 0.943 0.057
E23.0 Hypopituitarism
0.000 0.943 0.057
E11.4 With neurological complications
0.000 0.943 0.057
E11.1 With ketoacidosis
0.000 0.944 0.056
E23.6 Other disorders of pituitary gland
0.000 0.945 0.054
E27 Other disorders of adrenal gland
0.000 0.947 0.053
E66.0 Obesity due to excess calories
0.000 0.947 0.053
E20.1 Pseudohypoparathyroidism
0.001 0.948 0.051
E20.0 Idiopathic hypoparathyroidism
0.001 0.948 0.051
E83.3 Disorders of phosphorus metabolism
0.050 0.950 0.000
R40.2 Coma, unspecified
0.000 0.951 0.049
E83.9 Disorder of mineral metabolism, unspecified
0.049 0.951 0.000
K90-K93 Other diseases of the digestive system
0.000 0.953 0.047
L43.9 Lichen planus, unspecified
0.047 0.953 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.954 0.046
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.954 0.046
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.955 0.045
E20.8 Other hypoparathyroidism
0.001 0.955 0.044
E83.8 Other disorders of mineral metabolism
0.044 0.956 0.000
E83.2 Disorders of zinc metabolism
0.044 0.956 0.000
E83.0 Disorders of copper metabolism
0.044 0.956 0.000
E28.9 Ovarian dysfunction, unspecified
0.001 0.957 0.042
E28.8 Other ovarian dysfunction
0.001 0.957 0.042
E28.1 Androgen excess
0.001 0.957 0.042
E28.0 Oestrogen excess
0.001 0.957 0.042
E04.8 Other specified non-toxic goitre
0.000 0.958 0.041
E83.4 Disorders of magnesium metabolism
0.041 0.959 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.961 0.038
E27.0 Other adrenocortical overactivity
0.000 0.961 0.038
E28.3 Primary ovarian failure
0.001 0.964 0.035
E21.3 Hyperparathyroidism, unspecified
0.000 0.964 0.036
E83.5 Disorders of calcium metabolism
0.035 0.965 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.966 0.034
E27.1 Primary adrenocortical insufficiency
0.000 0.966 0.034
E11.3 With ophthalmic complications
0.000 0.968 0.032
E27.9 Disorder of adrenal gland, unspecified
0.000 0.968 0.031
E27.2 Addisonian crisis
0.000 0.969 0.030
R06 Abnormalities of breathing
0.030 0.970 0.000
E20.9 Hypoparathyroidism, unspecified
0.001 0.972 0.027
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.972 0.027
E27.8 Other specified disorders of adrenal gland
0.000 0.974 0.026
E04.9 Non-toxic goitre, unspecified
0.000 0.975 0.025
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.975 0.024
K93.1 Megacolon in Chagas' disease
0.000 0.975 0.024
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.975 0.024
R06.2 Wheezing
0.025 0.975 0.000
E14.9 Without complications
0.000 0.975 0.025
R06.6 Hiccough
0.024 0.976 0.000
E70-E90 Metabolic disorders
0.022 0.978 0.001
R06.7 Sneezing
0.022 0.978 0.000
R06.3 Periodic breathing
0.022 0.978 0.000
R06.1 Stridor
0.022 0.978 0.000
E89.2 Postprocedural hypoparathyroidism
0.021 0.979 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.021 0.979 0.000
E66.8 Other obesity
0.000 0.979 0.021
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.021 0.979 0.000
E04.0 Non-toxic diffuse goitre
0.001 0.980 0.020
E88 Other metabolic disorders
0.020 0.980 0.000
R06.4 Hyperventilation
0.019 0.981 0.000
R06.5 Mouth breathing
0.019 0.981 0.000
E74 Other disorders of carbohydrate metabolism
0.017 0.982 0.000
R61.9 Hyperhidrosis, unspecified
0.018 0.982 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.018 0.982 0.000
E79 Disorders of purine and pyrimidine metabolism
0.017 0.983 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.017 0.983 0.000
E89.3 Postprocedural hypopituitarism
0.016 0.984 0.000
E89.4 Postprocedural ovarian failure
0.016 0.984 0.000
E77 Disorders of glycoprotein metabolism
0.016 0.984 0.001
E76 Disorders of glycosaminoglycan metabolism
0.016 0.984 0.001
E72 Other disorders of amino-acid metabolism
0.016 0.984 0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.016 0.984 0.001
E70 Disorders of aromatic amino-acid metabolism
0.016 0.984 0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.016 0.984 0.001
E89.8 Other postprocedural endocrine and metabolic disorders
0.016 0.984 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.015 0.984 0.001
E88.2 Lipomatosis, not elsewhere classified
0.016 0.984 0.000
E84 Cystic fibrosis
0.015 0.984 0.001
E73 Lactose intolerance
0.015 0.984 0.000
R61.0 Localised hyperhidrosis
0.016 0.984 0.000
E89.1 Postprocedural hypoinsulinaemia
0.015 0.984 0.000
R61 Hyperhidrosis
0.015 0.985 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.015 0.985 0.000
E89.5 Postprocedural testicular hypofunction
0.015 0.985 0.000
E88.8 Other specified metabolic disorders
0.015 0.985 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.000 0.985 0.015
E74.3 Other disorders of intestinal carbohydrate absorption
0.014 0.985 0.000
E88.3 Tumour lysis syndrome
0.014 0.985 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.014 0.986 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.014 0.986 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.013 0.986 0.000
E88.9 Metabolic disorder, unspecified
0.013 0.986 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.013 0.987 0.000
E74.8 Other specified disorders of carbohydrate metabolism
0.013 0.987 0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.013 0.987 0.000
E74.2 Disorders of galactose metabolism
0.013 0.987 0.000
E74.1 Disorders of fructose metabolism
0.013 0.987 0.000
E74.0 Glycogen storage disease
0.013 0.987 0.000
E85 Amyloidosis
0.013 0.987 0.000
H50.0 Convergent concomitant strabismus
0.000 0.987 0.013
H50.9 Strabismus, unspecified
0.000 0.987 0.013
H50 Other strabismus
0.000 0.987 0.013
R40 Somnolence, stupor and coma
0.000 0.987 0.013
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.012 0.987 0.000
E79.8 Other disorders of purine and pyrimidine metabolism
0.012 0.987 0.000
E79.1 Lesch-Nyhan syndrome
0.012 0.987 0.000
R61.1 Generalised hyperhidrosis
0.013 0.987 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.012 0.987 0.000
H50.2 Vertical strabismus
0.000 0.988 0.012
C79.2 Secondary malignant neoplasm of skin
0.012 0.988 0.000
C79 Secondary malignant neoplasm of other sites
0.012 0.988 0.000
E28.2 Polycystic ovarian syndrome
0.001 0.988 0.011
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.011 0.988 0.001
E70.8 Other disorders of aromatic amino-acid metabolism
0.011 0.988 0.001
E70.3 Albinism
0.011 0.988 0.001
E70.2 Disorders of tyrosine metabolism
0.011 0.988 0.001
E70.1 Other hyperphenylalaninaemias
0.011 0.988 0.001
E70.0 Classical phenylketonuria
0.011 0.988 0.001
E71.3 Disorders of fatty-acid metabolism
0.011 0.988 0.001
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.011 0.988 0.001
E71.1 Other disorders of branched-chain amino-acid metabolism
0.011 0.988 0.001
E71.0 Maple-syrup-urine disease
0.011 0.988 0.001
E72.9 Disorder of amino-acid metabolism, unspecified
0.011 0.988 0.001
E72.8 Other specified disorders of amino-acid metabolism
0.011 0.988 0.001
E72.5 Disorders of glycine metabolism
0.011 0.988 0.001
E72.4 Disorders of ornithine metabolism
0.011 0.988 0.001
E72.3 Disorders of lysine and hydroxylysine metabolism
0.011 0.988 0.001
E72.2 Disorders of urea cycle metabolism
0.011 0.988 0.001
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.011 0.988 0.001
E72.0 Disorders of amino-acid transport
0.011 0.988 0.001
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.011 0.988 0.001
E76.8 Other disorders of glucosaminoglycan metabolism
0.011 0.988 0.001
E76.3 Mucopolysaccharidosis, unspecified
0.011 0.988 0.001
E76.2 Other mucopolysaccharidoses
0.011 0.988 0.001
E76.1 Mucopolysaccharidosis, type II
0.011 0.988 0.001
E76.0 Mucopolysaccharidosis, type I
0.011 0.988 0.001
E77.9 Disorder of glycoprotein metabolism, unspecified
0.011 0.988 0.001
E77.8 Other disorders of glycoprotein metabolism
0.011 0.988 0.001
E77.1 Defects in glycoprotein degradation
0.011 0.988 0.001
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.011 0.988 0.001
E04.1 Non-toxic single thyroid nodule
0.000 0.988 0.012
E75.6 Lipid storage disorder, unspecified
0.011 0.988 0.001
E75.4 Neuronal ceroid lipofuscinosis
0.011 0.988 0.001
E75.3 Sphingolipidosis, unspecified
0.011 0.988 0.001
E75.2 Other sphingolipidosis
0.011 0.988 0.001
E75.1 Other gangliosidosis
0.011 0.988 0.001
E75.0 GM2 gangliosidosis
0.011 0.988 0.001
E80.1 Porphyria cutanea tarda
0.011 0.988 0.000
E84.8 Cystic fibrosis with other manifestations
0.011 0.988 0.001
E84.1 Cystic fibrosis with intestinal manifestations
0.011 0.988 0.001
E84.0 Cystic fibrosis with pulmonary manifestations
0.011 0.988 0.001
E73.8 Other lactose intolerance
0.011 0.988 0.000
E73.1 Secondary lactase deficiency
0.011 0.988 0.000
E73.0 Congenital lactase deficiency
0.011 0.988 0.000
E75.5 Other lipid storage disorders
0.011 0.989 0.001
E84.9 Cystic fibrosis, unspecified
0.011 0.989 0.001
E73.9 Lactose intolerance, unspecified
0.011 0.989 0.000
C91.1 Chronic lymphocytic leukaemia
0.000 0.989 0.011
H50.4 Other and unspecified heterotropia
0.000 0.989 0.011
E04.2 Non-toxic multinodular goitre
0.000 0.990 0.010
E80.2 Other porphyria
0.010 0.990 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.010 0.990 0.000
E80.5 Crigler-Najjar syndrome
0.010 0.990 0.000
E80.3 Defects of catalase and peroxydase
0.010 0.990 0.000
E80.0 Hereditary erythropoietic porphyria
0.010 0.990 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.010 0.990 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.010 0.990 0.000
M07.3 Other psoriatic arthropathies
0.010 0.990 0.000
E85.8 Other amyloidosis
0.010 0.990 0.000
E80.6 Other disorders of bilirubin metabolism
0.009 0.990 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.009 0.990 0.000
E85.1 Neuropathic heredofamilial amyloidosis
0.009 0.990 0.000
E85.0 Nonneuropathic heredofamilial amyloidosis
0.009 0.990 0.000
C79.6 Secondary malignant neoplasm of ovary
0.010 0.990 0.000
R40.1 Stupor
0.000 0.990 0.009
H50.3 Intermittent heterotropia
0.000 0.990 0.009
E85.3 Secondary systemic amyloidosis
0.009 0.991 0.000
H50.5 Heterophoria
0.000 0.991 0.009
H50.8 Other specified strabismus
0.000 0.991 0.009
H50.6 Mechanical strabismus
0.000 0.991 0.009
H50.1 Divergent concomitant strabismus
0.000 0.991 0.009
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.009 0.991 0.000
E85.4 Organ-limited amyloidosis
0.008 0.991 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.991 0.009
N04.9 Unspecified
0.000 0.991 0.009
N05.9 Unspecified
0.000 0.991 0.009
M07.38 Other psoriatic arthropathies (Other)
0.008 0.991 0.000
N05 Unspecified nephritic syndrome
0.000 0.992 0.008
N04 Nephrotic syndrome
0.000 0.992 0.008
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.008 0.992 0.000
M50.3 Other cervical disk degeneration
0.008 0.992 0.000
N05.1 Focal and segmental glomerular lesions
0.000 0.992 0.008
M07.31 Other psoriatic arthropathies (Shoulder region)
0.008 0.992 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.008 0.992 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.008 0.992 0.000
E85.9 Amyloidosis, unspecified
0.007 0.992 0.001
T39.1 4-Aminophenol derivatives
0.008 0.992 0.000
N00-N08 Glomerular diseases
0.000 0.993 0.007
M07.33 Other psoriatic arthropathies (Forearm)
0.007 0.993 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.007 0.993 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.007 0.993 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.993 0.007
N04.2 Diffuse membranous glomerulonephritis
0.000 0.993 0.007
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.007 0.993 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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