TreeWAS – Variant ID: rs2395528

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R47.8 Other and unspecified speech disturbances	0.035	0.965	0.000
Z93.1 Gastrostomy status	0.030	0.970	0.000
Z93.0 Tracheostomy status	0.023	0.977	0.000
Z93 Artificial opening status	0.022	0.978	0.000
R47 Speech disturbances, not elsewhere classified	0.021	0.979	0.000
Z93.3 Colostomy status	0.020	0.980	0.000
N32 Other disorders of bladder	0.020	0.980	0.000
N32.8 Other specified disorders of bladder	0.019	0.981	0.000
N32.3 Diverticulum of bladder	0.019	0.981	0.000
N32.9 Bladder disorder, unspecified	0.019	0.981	0.000
Z93.8 Other artificial opening status	0.017	0.983	0.000
Z93.6 Other artificial openings of urinary tract status	0.017	0.983	0.000
R47.0 Dysphasia and aphasia	0.017	0.983	0.000
N32.0 Bladder-neck obstruction	0.015	0.985	0.000
N32.4 Rupture of bladder, nontraumatic	0.014	0.985	0.000
N32.1 Vesicointestinal fistula	0.015	0.985	0.000
Z93.9 Artificial opening status, unspecified	0.014	0.986	0.000
N32.2 Vesical fistula, not elsewhere classified	0.014	0.986	0.000
N42.8 Other specified disorders of prostate	0.014	0.986	0.000
Z93.5 Cystostomy status	0.014	0.986	0.000
Z93.4 Other artificial openings of gastro-intestinal tract status	0.013	0.986	0.000
R47.1 Dysarthria and anarthria	0.012	0.988	0.000
R47-R49 Symptoms and signs involving speech and voice	0.012	0.988	0.000
R49 Voice disturbances	0.010	0.990	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.990	0.010
K86.8 Other specified diseases of pancreas	0.010	0.990	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.991	0.009
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.009	0.991	0.000
R49.1 Aphonia	0.008	0.992	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.992	0.008
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.992	0.008
N42 Other disorders of prostate	0.008	0.992	0.000
R49.0 Dysphonia	0.008	0.992	0.000
R49.8 Other and unspecified voice disturbances	0.007	0.993	0.000
R49.2 Hypernasality and hyponasality	0.007	0.993	0.000
N42.1 Congestion and haemorrhage of prostate	0.007	0.993	0.000
R48.0 Dyslexia and alexia	0.007	0.993	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.007	0.993	0.000
Z88.2 Personal history of allergy to sulphonamides	0.007	0.993	0.000
R48.8 Other and unspecified symbolic dysfunctions	0.007	0.993	0.000
R48.2 Apraxia	0.007	0.993	0.000
R48.1 Agnosia	0.007	0.993	0.000
K22.7 Barrett's oesophagus	0.000	0.993	0.007
C85.1 B-cell lymphoma, unspecified	0.000	0.994	0.006
N42.3 Dysplasia of prostate	0.006	0.994	0.000
C85.0 Lymphosarcoma	0.000	0.994	0.006
N42.9 Disorder of prostate, unspecified	0.006	0.994	0.000
N42.0 Calculus of prostate	0.006	0.994	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.994	0.006
V18 Pedal cyclist injured in noncollision transport accident	0.006	0.994	0.000
V18.0 Driver injured in nontraffic accident	0.005	0.995	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.995	0.005
N42.2 Atrophy of prostate	0.005	0.995	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.005	0.995	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.005	0.995	0.000
N81.4 Uterovaginal prolapse, unspecified	0.005	0.995	0.000
C81 Hodgkin's disease	0.000	0.995	0.005
C88 Malignant immunoproliferative diseases	0.000	0.995	0.005
V18.1 Passenger injured in nontraffic accident	0.005	0.995	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.000	0.995	0.005
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.000	0.995	0.005
V18.3 Person injured while boarding or alighting	0.005	0.995	0.000
C94 Other leukaemias of specified cell type	0.000	0.995	0.005
V18.5 Passenger injured in traffic accident	0.005	0.995	0.000
Z43.3 Attention to colostomy	0.004	0.996	0.000
V18.9 Unspecified pedal cyclist injured in traffic accident	0.004	0.996	0.000
V18.4 Driver injured in traffic accident	0.004	0.996	0.000
C93 Monocytic leukaemia	0.000	0.996	0.004
C86 Other specified types of T/NK-cell lymphoma	0.000	0.996	0.004
C81.0 Lymphocytic predominance	0.000	0.996	0.004
C91.5 Adult T-cell leukaemia	0.000	0.996	0.004
C81.7 Other Hodgkin's disease	0.000	0.996	0.004
C91 Lymphoid leukaemia	0.000	0.996	0.004
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.996	0.004
Z43 Attention to artificial openings	0.004	0.996	0.000
C92.1 Chronic myeloid leukaemia	0.000	0.996	0.004
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.996	0.004
C92 Myeloid leukaemia	0.000	0.996	0.004
C81.9 Hodgkin's disease, unspecified	0.000	0.996	0.004
C84.5 Other and unspecified T-cell lymphomas	0.000	0.996	0.004
C94.4 Acute panmyelosis	0.000	0.996	0.004
M79.2 Neuralgia and neuritis, unspecified	0.000	0.996	0.004
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.996	0.004
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.000	0.996	0.004
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.996	0.004
C81.3 Lymphocytic depletion	0.000	0.996	0.004
C88.9 Malignant immunoproliferative disease, unspecified	0.000	0.996	0.004
C88.7 Other malignant immunoproliferative diseases	0.000	0.996	0.004
C88.3 Immunoproliferative small intestinal disease	0.000	0.996	0.004
C88.2 Gamma heavy chain disease	0.000	0.996	0.004
C88.1 Alpha heavy chain disease	0.000	0.996	0.004
C81.2 Mixed cellularity	0.000	0.996	0.004
C93.1 Chronic monocytic leukaemia	0.000	0.996	0.004
C81.1 Nodular sclerosis	0.000	0.996	0.004
C86.5 Angioimmunoblastic T-cell lymphoma	0.000	0.996	0.004
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.004	0.996	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.004	0.996	0.000
M67.8 Other specified disorders of synovium and tendon	0.004	0.996	0.000
Z43.8 Attention to other artificial openings	0.004	0.996	0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.000	0.996	0.004
C94.7 Other specified leukaemias	0.000	0.996	0.003
C94.5 Acute myelofibrosis	0.000	0.996	0.003
C94.3 Mast cell leukaemia	0.000	0.996	0.003
C94.2 Acute megakaryoblastic leukaemia	0.000	0.996	0.003
C94.1 Chronic erythraemia	0.000	0.996	0.003
C94.0 Acute erythraemia and erythroleukaemia	0.000	0.996	0.003
Z43.1 Attention to gastrostomy	0.004	0.996	0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.003	0.997	0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.003	0.997	0.000
C93.9 Monocytic leukaemia, unspecified	0.000	0.997	0.003
C93.7 Other monocytic leukaemia	0.000	0.997	0.003
C93.3 Juvenile myelomonocytic leukaemia	0.000	0.997	0.003
C93.2 Subacute monocytic leukaemia	0.000	0.997	0.003
C93.0 Acute monocytic leukaemia	0.000	0.997	0.003
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.000	0.997	0.003
C86.4 Blastic NK-cell lymphoma	0.000	0.997	0.003
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.000	0.997	0.003
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.000	0.997	0.003
C86.1 Hepatosplenic T-cell lymphoma	0.000	0.997	0.003
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.000	0.997	0.003
O46.9 Antepartum haemorrhage, unspecified	0.003	0.997	0.000
Z43.0 Attention to tracheostomy	0.003	0.997	0.000
C95 Leukaemia of unspecified cell type	0.000	0.997	0.003
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.000	0.997	0.003
K70.0 Alcoholic fatty liver	0.003	0.997	0.000
C92.5 Acute myelomonocytic leukaemia	0.000	0.997	0.003
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.000	0.997	0.003
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.997	0.003
C91.7 Other lymphoid leukaemia	0.000	0.997	0.003
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.997	0.003
C91.3 Prolymphocytic leukaemia	0.000	0.997	0.003
C91.2 Subacute lymphocytic leukaemia	0.000	0.997	0.003
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.997	0.003
C84.9 Mature T/NK-cell lymphoma, unspecified	0.000	0.997	0.003
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.000	0.997	0.003
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.000	0.997	0.003
C84.3 Lymphoepithelioid lymphoma	0.000	0.997	0.003
C84.2 T-zone lymphoma	0.000	0.997	0.003
C84.1 Sezary's diease	0.000	0.997	0.003
C91.1 Chronic lymphocytic leukaemia	0.000	0.997	0.003
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
Z43.5 Attention to cyctostomy	0.003	0.997	0.000
Z43.9 Attention to unspecified artificial opening	0.003	0.997	0.000
Z43.7 Attention to artificial vagina	0.003	0.997	0.000
C84.4 Peripheral T-cell lymphoma	0.000	0.997	0.003
C92.7 Other myeloid leukaemia	0.000	0.997	0.003
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.997	0.003
C96.8 Histiocytic sarcoma	0.000	0.997	0.003
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.997	0.003
C96.6 Unifocal Langerhans-cell histiocytosis	0.000	0.997	0.003
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.000	0.997	0.003
C96.4 Sarcoma of dendritic cells (accessory cells)	0.000	0.997	0.003
C96.3 True histiocytic lymphoma	0.000	0.997	0.003
C96.2 Malignant mast cell tumour	0.000	0.997	0.003
C96.1 Malignant histiocytosis	0.000	0.997	0.003
C96.0 Letterer-Siwe disease	0.000	0.997	0.003
C84.0 Mycosis fungoides	0.000	0.997	0.003
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.997	0.003
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.997	0.003
C92.3 Myeloid sarcoma	0.000	0.997	0.003
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.000	0.997	0.003
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.000	0.997	0.003
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.000	0.997	0.003
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.000	0.997	0.003
Q21.1 Atrial septal defect	0.000	0.997	0.003
C91.0 Acute lymphoblastic leukaemia	0.000	0.997	0.003
C84.8 Cutaneous T-cell lymphoma, unspecified	0.000	0.997	0.003
C91.4 Hairy-cell leukaemia	0.000	0.997	0.003
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.997	0.003
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
K70 Alcoholic liver disease	0.003	0.997	0.000
K70.9 Alcoholic liver disease, unspecified	0.003	0.997	0.000
C91.9 Lymphoid leukaemia, unspecified	0.000	0.997	0.003
C92.9 Myeloid leukaemia, unspecified	0.000	0.997	0.003
C92.4 Acute promyelocytic leukaemia	0.000	0.997	0.003
C92.2 Subacute myeloid leukaemia	0.000	0.997	0.003
K70.3 Alcoholic cirrhosis of liver	0.003	0.997	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.000	0.997	0.003
C83.7 Burkitt's tumour	0.000	0.997	0.003
N13.8 Other obstructive and reflux uropathy	0.003	0.997	0.000
C95.7 Other leukaemia of unspecified cell type	0.000	0.997	0.002
C95.2 Subacute leukaemia of unspecified cell type	0.000	0.997	0.002
C83.6 Undifferentiated (diffuse)	0.000	0.997	0.003
C83.4 Immunoblastic (diffuse)	0.000	0.997	0.003
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.997	0.003
K70.1 Alcoholic hepatitis	0.003	0.997	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.997	0.003
C83.0 Small cell (diffuse)	0.000	0.997	0.003
I05.0 Mitral stenosis	0.000	0.997	0.003
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.997	0.003
C83.2 Mixed small and large cell (diffuse)	0.000	0.997	0.002
C95.0 Acute leukaemia of unspecified cell type	0.000	0.997	0.002
D05 Carcinoma in situ of breast	0.003	0.997	0.000
C95.9 Leukaemia, unspecified	0.000	0.997	0.002
C95.1 Chronic leukaemia of unspecified cell type	0.000	0.997	0.002
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.002	0.997	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.002	0.997	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.002	0.998	0.000
C83.5 Lymphoblastic (diffuse)	0.000	0.998	0.002
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.002	0.998	0.000
C92.0 Acute myeloid leukaemia	0.000	0.998	0.002
I05.2 Mitral stenosis with insufficiency	0.000	0.998	0.002
N13 Obstructive and reflux uropathy	0.002	0.998	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.998	0.002
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.002	0.998	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.998	0.002
C83.1 Small cleaved cell (diffuse)	0.000	0.998	0.002
N13.7 Vesicoureteral-reflux-associated uropathy	0.002	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.002	0.998	0.000
N13.6 Pyonephrosis	0.002	0.998	0.000
A02.0 Salmonella gastro-enteritis	0.000	0.998	0.002
C82.4 Follicular lymphoma grade IIIb	0.000	0.998	0.002
M67.43 Ganglion, wrist	0.002	0.998	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.002	0.998	0.000
O46.8 Other antepartum haemorrhage	0.002	0.998	0.000
C82.6 Cutaneous follicle centre lymphoma	0.000	0.998	0.002
C82.5 Diffuse follicle centre lymphoma	0.000	0.998	0.002
D05.7 Other carcinoma in situ of breast	0.002	0.998	0.000
D05.1 Intraductal carcinoma in situ	0.002	0.998	0.000
N13.3 Other and unspecified hydronephrosis	0.002	0.998	0.000
O04.4 Incomplete, without complication	0.000	0.998	0.002
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.002	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
F00 Dementia in Alzheimer's disease	0.002	0.998	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.002	0.998	0.000
C83.3 Large cell (diffuse)	0.000	0.998	0.002
F10.3 Withdrawal state	0.002	0.998	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.002	0.998	0.000
W06.0 Home	0.002	0.998	0.000
I05 Rheumatic mitral valve diseases	0.000	0.998	0.002
S32.0 Fracture of lumbar vertebra	0.002	0.998	0.000
C82.2 Large cell, follicular	0.000	0.998	0.002
H53.4 Visual field defects	0.002	0.998	0.000
M54.12 Radiculopathy (Cervical region)	0.000	0.998	0.002
C82.3 Follicular lymphoma grade IIIa	0.000	0.998	0.002
C90.2 Plasmacytoma, extramedullary	0.000	0.998	0.002
C90.1 Plasma cell leukaemia	0.000	0.998	0.002
M67.4 Ganglion	0.002	0.998	0.000
M67 Other disorders of synovium and tendon	0.002	0.998	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.002	0.998	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.002	0.998	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.002	0.998	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.998	0.002
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.002	0.998	0.000
C90.3 Solitary plasmacytoma	0.000	0.998	0.002
F00.0 Dementia in Alzheimer's disease with early onset	0.002	0.998	0.000
K74.3 Primary biliary cirrhosis	0.002	0.998	0.000
N99.5 Malfunction of external stoma of urinary tract	0.002	0.998	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.002	0.998	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.002	0.998	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.002	0.998	0.000
Z97.8 Presence of other specified devices	0.000	0.998	0.002
D05.0 Lobular carcinoma in situ	0.002	0.998	0.000
C49.4 Connective and soft tissue of abdomen	0.000	0.998	0.002
I51.9 Heart disease, unspecified	0.002	0.998	0.000
J15.1 Pneumonia due to Pseudomonas	0.002	0.998	0.000
C82.0 Small cleaved cell, follicular	0.000	0.998	0.002
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.002	0.998	0.000
Z93.2 Ileostomy status	0.002	0.998	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.002	0.998	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.002	0.998	0.000
F05.9 Delirium, unspecified	0.002	0.998	0.000
M67.0 Short Achilles tendon (acquired)	0.002	0.998	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.002	0.998	0.000
V10-V19 Pedal cyclist injured in transport accident	0.002	0.998	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.002	0.998	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.002	0.998	0.000
S37 Injury of urinary and pelvic organs	0.002	0.998	0.000
S31 Open wound of abdomen, lower back and pelvis	0.002	0.998	0.000
C49.3 Connective and soft tissue of thorax	0.000	0.998	0.002
J31.0 Chronic rhinitis	0.000	0.998	0.002
N99.0 Postprocedural renal failure	0.002	0.998	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.000	0.998	0.002
S32.01 Fracture of lumbar vertebra (open)	0.002	0.998	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.002	0.998	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.002	0.998	0.000
H25.8 Other senile cataract	0.000	0.998	0.002
K70.4 Alcoholic hepatic failure	0.002	0.998	0.000
S36 Injury of intra-abdominal organs	0.002	0.998	0.000
S32 Fracture of lumbar spine and pelvis	0.002	0.998	0.000
S33.1 Dislocation of lumbar vertebra	0.002	0.998	0.000
M67.49 Ganglion, multiple sites	0.002	0.998	0.000
M67.45 Ganglion, hip	0.002	0.998	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.002	0.998	0.000
M67.3 Transient synovitis	0.002	0.998	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.002	0.998	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.002	0.998	0.000
N10-N16 Renal tubulo-interstitial diseases	0.002	0.998	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.998	0.002
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.998	0.002
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.001	0.998	0.000
I05.8 Other mitral valve diseases	0.000	0.998	0.001
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.002	0.998	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.001	0.998	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.001	0.998	0.000
S37.2 Injury of bladder	0.001	0.998	0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van	0.002	0.998	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.002	0.998	0.000
V11 Pedal cyclist injured in collision with other pedal cycle	0.002	0.998	0.000
S37.3 Injury of urethra	0.001	0.998	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.002	0.998	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.998	0.002
O42.9 Premature rupture of membranes, unspecified	0.002	0.998	0.000
M67.47 Ganglion, ankle and foot	0.001	0.998	0.000
E78.2 Mixed hyperlipidaemia	0.002	0.998	0.000
K86.9 Disease of pancreas, unspecified	0.002	0.998	0.000
S31.4 Open wound of vagina and vulva	0.001	0.998	0.000
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.001	0.998	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.001	0.998	0.000
S33.4 Traumatic rupture of symphysis pubis	0.001	0.998	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.001	0.998	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.001	0.998	0.000
S36.6 Injury of rectum	0.001	0.998	0.000
S37.9 Injury of unspecified pelvic organ	0.001	0.998	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.002	0.998	0.000
V10 Pedal cyclist injured in collision with pedestrian or animal	0.001	0.998	0.000
C49.5 Connective and soft tissue of pelvis	0.000	0.998	0.001
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.001	0.998	0.000
S31.5 Open wound of other and unspecified external genital organs	0.001	0.998	0.000
S31.3 Open wound of scrotum and testes	0.001	0.998	0.000
S37.8 Injury of other pelvic organs	0.001	0.998	0.000
S37.7 Injury of multiple pelvic organs	0.001	0.998	0.000
S37.6 Injury of uterus	0.001	0.998	0.000
S37.5 Injury of Fallopian tube	0.001	0.998	0.000
S37.4 Injury of ovary	0.001	0.998	0.000
S37.1 Injury of ureter	0.001	0.998	0.000
V11.4 Driver injured in traffic accident	0.001	0.998	0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle	0.001	0.998	0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle	0.001	0.998	0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle	0.001	0.998	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.998	0.001
H02.3 Blepharochalasis	0.000	0.998	0.002
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.001	0.998	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.001	0.998	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.001	0.998	0.000
S34.4 Injury of lumbosacral plexus	0.001	0.998	0.000
S34.3 Injury of cauda equina	0.001	0.998	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.001	0.998	0.000
S37.20 Injury of bladder (without open wound into cavity)	0.001	0.998	0.000
F01.9 Vascular dementia, unspecified	0.002	0.998	0.000
S20.2 Contusion of thorax	0.002	0.998	0.000
S31.2 Open wound of penis	0.001	0.998	0.000
S32.2 Fracture of coccyx	0.001	0.998	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.001	0.998	0.000
S36.7 Injury of multiple intra-abdominal organs	0.001	0.998	0.000
S36.5 Injury of colon	0.001	0.998	0.000
S36.4 Injury of small intestine	0.001	0.998	0.000
S36.3 Injury of stomach	0.001	0.998	0.000
S36.2 Injury of pancreas	0.001	0.998	0.000
S37.0 Injury of kidney	0.001	0.998	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.001	0.998	0.000
R01.0 Benign and innocent cardiac murmurs	0.002	0.998	0.000
S34.1 Other injury of lumbar spinal cord	0.001	0.998	0.000
S36.1 Injury of liver or gallbladder	0.001	0.998	0.000
S36.0 Injury of spleen	0.001	0.998	0.000
V13.0 Driver injured in nontraffic accident	0.001	0.998	0.000
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.001	0.998	0.000
N99.2 Postprocedural adhesions of vagina	0.001	0.998	0.000
S33.5 Sprain and strain of lumbar spine	0.001	0.998	0.000
N15 Other renal tubulo-interstitial diseases	0.001	0.998	0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus	0.001	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.001
S30.0 Contusion of lower back and pelvis	0.001	0.998	0.000
S31.0 Open wound of lower back and pelvis	0.001	0.998	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.001	0.998	0.000
S38.2 Traumatic amputation of external genital organs	0.001	0.998	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.001	0.998	0.000
S38.0 Crushing injury of external genital organs	0.001	0.998	0.000
C41.9 Bone and articular cartilage, unspecified	0.000	0.999	0.001
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.999	0.001
H21.8 Other specified disorders of iris and ciliary body	0.001	0.999	0.000
K11.5 Sialolithiasis	0.000	0.999	0.001
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.001	0.999	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.001	0.999	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.001	0.999	0.000
S35.5 Injury of iliac blood vessels	0.001	0.999	0.000
S35.4 Injury of renal blood vessels	0.001	0.999	0.000
S35.3 Injury of portal or splenic vein	0.001	0.999	0.000
S35.1 Injury of inferior vena cava	0.001	0.999	0.000
S35.0 Injury of abdominal aorta	0.001	0.999	0.000
S36.8 Injury of other intra-abdominal organs	0.001	0.999	0.000
S36.60 Injury of rectum (without open wound into cavity)	0.001	0.999	0.000
S37.21 Injury of bladder (with open wound into cavity)	0.001	0.999	0.000
S37.30 Injury of urethra (without open wound into cavity)	0.001	0.999	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.001	0.999	0.000
Q61.5 Medullary cystic kidney	0.001	0.999	0.000
K86 Other diseases of pancreas	0.001	0.999	0.000
M84.01 Malunion of fracture (Shoulder region)	0.001	0.999	0.000
C41.0 Bones of skull and face	0.000	0.999	0.001
H69.9 Eustachian tube disorder, unspecified	0.001	0.999	0.000
V11.5 Passenger injured in traffic accident	0.001	0.999	0.000
V11.3 Person injured while boarding or alighting	0.001	0.999	0.000
V11.2 Unspecified pedal cyclist injured in nontraffic accident	0.001	0.999	0.000
V11.1 Passenger injured in nontraffic accident	0.001	0.999	0.000
V13.9 Unspecified pedal cyclist injured in traffic accident	0.001	0.999	0.000
V13.4 Driver injured in traffic accident	0.001	0.999	0.000
V13.2 Unspecified pedal cyclist injured in nontraffic accident	0.001	0.999	0.000
V13.5 Passenger injured in traffic accident	0.001	0.999	0.000
V13.3 Person injured while boarding or alighting	0.001	0.999	0.000
V13.1 Passenger injured in nontraffic accident	0.001	0.999	0.000
W02.9 Unspecified place	0.001	0.999	0.000
N10 Acute tubulo-interstitial nephritis	0.001	0.999	0.000
V19 Pedal cyclist injured in other and unspecified transport accidents	0.001	0.999	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.001	0.999	0.000
S36.41 Injury of small intestine (with open wound into cavity)	0.001	0.999	0.000
S37.31 Injury of urethra (with open wound into cavity)	0.001	0.999	0.000
S37.90 Injury of unspecified pelvic organ (without open wound into cavity)	0.001	0.999	0.000
C90.0 Multiple myeloma	0.000	0.999	0.001
H21.5 Other adhesions and disruptions of iris and ciliary body	0.001	0.999	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.001	0.999	0.000
N14.3 Nephropathy induced by heavy metals	0.001	0.999	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.001	0.999	0.000
N14.0 Analgesic nephropathy	0.001	0.999	0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.001	0.999	0.000
S32.1 Fracture of sacrum	0.001	0.999	0.000
S35.2 Injury of coeliac or mesenteric artery	0.001	0.999	0.000
V11.0 Driver injured in nontraffic accident	0.001	0.999	0.000
S36.61 Injury of rectum (with open wound into cavity)	0.001	0.999	0.000
S37.91 Injury of unspecified pelvic organ (with open wound into cavity)	0.001	0.999	0.000
C41.2 Vertebral column	0.000	0.999	0.001
H21.1 Other vascular disorders of iris and ciliary body	0.001	0.999	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.001	0.999	0.000
V10.9 Unspecified pedal cyclist injured in traffic accident	0.001	0.999	0.000
V10.5 Passenger injured in traffic accident	0.001	0.999	0.000
V10.4 Driver injured in traffic accident	0.001	0.999	0.000
V10.3 Person injured while boarding or alighting	0.001	0.999	0.000
V10.2 Unspecified pedal cyclist injured in nontraffic accident	0.001	0.999	0.000
V10.1 Passenger injured in nontraffic accident	0.001	0.999	0.000
V10.0 Driver injured in nontraffic accident	0.001	0.999	0.000
F01 Vascular dementia	0.001	0.999	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.001	0.999	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.000	0.999	0.001
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.001	0.999	0.000
S36.50 Injury of colon (without open wound into cavity)	0.001	0.999	0.000
S37.11 Injury of ureter (with open wound into cavity)	0.001	0.999	0.000
S37.10 Injury of ureter (without open wound into cavity)	0.001	0.999	0.000
S37.41 Injury of ovary (with open wound into cavity)	0.001	0.999	0.000
S37.40 Injury of ovary (without open wound into cavity)	0.001	0.999	0.000
S37.51 Injury of fallopian tube (with open wound into cavity)	0.001	0.999	0.000
S37.50 Injury of fallopian tube (without open wound into cavity)	0.001	0.999	0.000
S37.61 Injury of uterus (with open wound into cavity)	0.001	0.999	0.000
S37.60 Injury of uterus (without open wound into cavity)	0.001	0.999	0.000
S37.71 Injury of multiple pelvic organs (with open wound into cavity)	0.001	0.999	0.000
S37.70 Injury of multiple pelvic organs (without open wound into cavity)	0.001	0.999	0.000
S37.81 Injury of other pelvic organs (with open wound into cavity)	0.001	0.999	0.000
S37.80 Injury of other pelvic organs (without open wound into cavity)	0.001	0.999	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.001	0.999	0.000
V12.4 Driver injured in traffic accident	0.001	0.999	0.000
V12.9 Unspecified pedal cyclist injured in traffic accident	0.001	0.999	0.000
V12.5 Passenger injured in traffic accident	0.001	0.999	0.000
V12.3 Person injured while boarding or alighting	0.001	0.999	0.000
V12.2 Unspecified pedal cyclist injured in nontraffic accident	0.001	0.999	0.000
V12.1 Passenger injured in nontraffic accident	0.001	0.999	0.000
V12.0 Driver injured in nontraffic accident	0.001	0.999	0.000
V15.9 Unspecified pedal cyclist injured in traffic accident	0.001	0.999	0.000
V15.5 Passenger injured in traffic accident	0.001	0.999	0.000
V15.4 Driver injured in traffic accident	0.001	0.999	0.000
V15.3 Person injured while boarding or alighting	0.001	0.999	0.000
V15.2 Unspecified pedal cyclist injured in nontraffic accident	0.001	0.999	0.000
V15.1 Passenger injured in nontraffic accident	0.001	0.999	0.000
V15.0 Driver injured in nontraffic accident	0.001	0.999	0.000
V16.9 Unspecified pedal cyclist injured in traffic accident	0.001	0.999	0.000
V16.5 Passenger injured in traffic accident	0.001	0.999	0.000
V16.4 Driver injured in traffic accident	0.001	0.999	0.000
V16.3 Person injured while boarding or alighting	0.001	0.999	0.000
V16.2 Unspecified pedal cyclist injured in nontraffic accident	0.001	0.999	0.000
V16.1 Passenger injured in nontraffic accident	0.001	0.999	0.000
V16.0 Driver injured in nontraffic accident	0.001	0.999	0.000
M54.19 Radiculopathy (Site unspecified)	0.000	0.999	0.001
S36.51 Injury of colon (with open wound into cavity)	0.001	0.999	0.000
S37.01 Injury of kidney (with open wound into cavity)	0.001	0.999	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.999	0.001
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.001	0.999	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.001	0.999	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.001	0.999	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.001	0.999	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.001	0.999	0.000
N99.1 Postprocedural urethral stricture	0.001	0.999	0.000
L52 Erythema nodosum	0.000	0.999	0.001
S32.21 Fracture of coccyx (open)	0.001	0.999	0.000
S32.20 Fracture of coccyx (closed)	0.001	0.999	0.000
S36.01 Injury of spleen (with open wound into cavity)	0.001	0.999	0.000
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.001	0.999	0.000
S36.21 Injury of pancreas (with open wound into cavity)	0.001	0.999	0.000
S36.20 Injury of pancreas (without open wound into cavity)	0.001	0.999	0.000
S36.31 Injury of stomach (with open wound into cavity)	0.001	0.999	0.000
S36.30 Injury of stomach (without open wound into cavity)	0.001	0.999	0.000
S36.71 Injury of multiple intra-abdominal organs (with open wound into cavity)	0.001	0.999	0.000
S36.70 Injury of multiple intra-abdominal organs (without open wound into cavity)	0.001	0.999	0.000
S36.91 Injury of unspecified intra-abdominal organ (with open wound into cavity)	0.001	0.999	0.000
S36.90 Injury of unspecified intra-abdominal organ (without open wound into cavity)	0.001	0.999	0.000
E83.1 Disorders of iron metabolism	0.001	0.999	0.000
V11.9 Unspecified pedal cyclist injured in traffic accident	0.001	0.999	0.000
H21 Other disorders of iris and ciliary body	0.001	0.999	0.000
S32.10 Fracture of sacrum (closed)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations