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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs241405
log Bayes Factor = 120.324
Chromosome 6   position 32,865,798  (GRCh37) Explore rs241405 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
M35.3 Polymyalgia rheumatica
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
J45.9 Asthma, unspecified
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
E14 Unspecified diabetes mellitus
0.000 0.004 0.996
E10.2 With renal complications
0.000 0.013 0.987
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.013 0.987
E14.3 With ophthalmic complications
0.000 0.016 0.984
E10.8 With unspecified complications
0.000 0.017 0.983
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.022 0.978
E10.5 With peripheral circulatory complications
0.000 0.037 0.963
E10.0 With coma
0.000 0.043 0.957
H36.0 Diabetic retinopathy
0.000 0.047 0.953
E11 Non-insulin-dependent diabetes mellitus
0.000 0.054 0.946
J33.0 Polyp of nasal cavity
0.000 0.067 0.933
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.070 0.930
J33 Nasal polyp
0.000 0.086 0.914
J33.9 Nasal polyp, unspecified
0.000 0.095 0.905
E06 Thyroiditis
0.000 0.097 0.903
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.101 0.899
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.113 0.887
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.123 0.877
E14.9 Without complications
0.000 0.151 0.849
E11.2 With renal complications
0.000 0.163 0.837
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.164 0.836
E10.6 With other specified complications
0.000 0.175 0.825
M06 Other rheumatoid arthritis
0.000 0.180 0.820
E14.8 With unspecified complications
0.000 0.185 0.815
E11.1 With ketoacidosis
0.000 0.191 0.809
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.203 0.797
E14.6 With other specified complications
0.000 0.204 0.796
E14.1 With ketoacidosis
0.000 0.208 0.792
E11.5 With peripheral circulatory complications
0.000 0.213 0.787
E11.9 Without complications
0.000 0.214 0.786
J33.8 Other polyp of sinus
0.000 0.217 0.783
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.228 0.772
E06.3 Autoimmune thyroiditis
0.000 0.231 0.769
M05 Seropositive rheumatoid arthritis
0.000 0.233 0.767
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.233 0.767
M05-M14 Inflammatory polyarthropathies
0.000 0.234 0.765
E11.3 With ophthalmic complications
0.000 0.236 0.764
E11.6 With other specified complications
0.000 0.242 0.758
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.737 0.263 0.000
L40.9 Psoriasis, unspecified
0.729 0.271 0.000
E06.9 Thyroiditis, unspecified
0.000 0.277 0.723
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.285 0.715
E14.7 With multiple complications
0.000 0.286 0.714
E14.0 With coma
0.000 0.286 0.714
E06.5 Other chronic thyroiditis
0.000 0.295 0.705
J45 Asthma
0.000 0.295 0.705
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.299 0.701
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.302 0.698
E03.1 Congenital hypothyroidism without goitre
0.000 0.302 0.697
E40-E46 Malnutrition
0.000 0.305 0.695
E03.8 Other specified hypothyroidism
0.000 0.309 0.691
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.310 0.690
J33.1 Polypoid sinus degeneration
0.000 0.317 0.683
E11.7 With multiple complications
0.000 0.321 0.679
M06.4 Inflammatory polyarthropathy
0.000 0.323 0.677
M35 Other systemic involvement of connective tissue
0.000 0.326 0.674
E13 Other specified diabetes mellitus
0.000 0.327 0.673
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.327 0.673
E14.2 Withrenal complications
0.000 0.339 0.661
E06.1 Subacute thyroiditis
0.000 0.339 0.661
K90 Intestinal malabsorption
0.000 0.345 0.655
E06.4 Drug-induced thyroiditis
0.000 0.352 0.647
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.352 0.647
E06.0 Acute thyroiditis
0.000 0.352 0.647
E14.4 With neurological complications
0.000 0.354 0.646
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.358 0.642
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.362 0.638
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.625 0.374 0.000
E05.8 Other thyrotoxicosis
0.000 0.387 0.613
L40 Psoriasis
0.601 0.399 0.000
E11.8 With unspecified complications
0.000 0.400 0.600
M05.8 Other seropositive rheumatoid arthritis
0.000 0.404 0.596
E50-E64 Other nutritional deficiencies
0.000 0.404 0.595
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.407 0.593
M06.2 Rheumatoid bursitis
0.000 0.412 0.588
J40-J47 Chronic lower respiratory diseases
0.000 0.418 0.582
J44 Other chronic obstructive pulmonary disease
0.000 0.421 0.579
C82.0 Small cleaved cell, follicular
0.579 0.421 0.000
L40.5 Arthropathic psoriasis
0.579 0.421 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.422 0.578
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.424 0.576
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.430 0.570
E20-E35 Disorders of other endocrine glands
0.000 0.431 0.569
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.435 0.565
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.435 0.565
J43 Emphysema
0.000 0.443 0.557
K90.9 Intestinal malabsorption, unspecified
0.000 0.444 0.556
E07 Other disorders of thyroid
0.000 0.445 0.555
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.447 0.553
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.450 0.550
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.450 0.550
M05.1 Rheumatoid lung disease
0.000 0.450 0.550
M05.0 Felty's syndrome
0.000 0.450 0.550
M06.1 Adult-onset Still's disease
0.000 0.450 0.549
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.451 0.549
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.453 0.547
J43.9 Emphysema, unspecified
0.000 0.453 0.547
M35.7 Hypermobility syndrome
0.000 0.454 0.546
M20-M25 Other joint disorders
0.000 0.458 0.542
M08 Juvenile arthritis
0.000 0.467 0.533
C82.3 Follicular lymphoma grade IIIa
0.531 0.469 0.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.471 0.529
M12 Other specific arthropathies
0.000 0.472 0.528
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.475 0.525
E61 Deficiency of other nutrient elements
0.000 0.481 0.519
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.516 0.484 0.000
E16.1 Other hypoglycaemia
0.000 0.485 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.486 0.514
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.487 0.513
M06.8 Other specified rheumatoid arthritis
0.000 0.488 0.512
M86-M90 Other osteopathies
0.000 0.493 0.507
M34 Systemic sclerosis
0.000 0.499 0.501
J45.0 Predominantly allergic asthma
0.000 0.500 0.500
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.501 0.499
E45 Retarded development following protein-energy malnutrition
0.000 0.501 0.499
E43 Unspecified severe protein-energy malnutrition
0.000 0.501 0.499
E42 Marasmic kwashiorkor
0.000 0.501 0.499
E41 Nutritional marasmus
0.000 0.501 0.499
E40 Kwashiorkor
0.000 0.501 0.499
L40.1 Generalised pustular psoriasis
0.498 0.502 0.000
M86 Osteomyelitis
0.000 0.502 0.498
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.503 0.496
M86.9 Osteomyelitis, unspecified
0.000 0.508 0.492
M32 Systemic lupus erythematosus
0.000 0.510 0.490
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.514 0.486
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.514 0.486
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.514 0.486
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.514 0.486
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.514 0.486
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.514 0.486
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.514 0.486
E11.4 With neurological complications
0.000 0.516 0.484
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.517 0.483
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.517 0.483
M35.5 Multifocal fibrosclerosis
0.000 0.517 0.483
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.517 0.483
E13.8 With unspecified complications
0.000 0.517 0.482
E13.7 With multiple complications
0.000 0.517 0.482
E13.6 With other specified complications
0.000 0.517 0.482
E13.5 With peripheral circulatory complications
0.000 0.517 0.482
E13.4 With neurological complications
0.000 0.517 0.482
E13.2 With renal complications
0.000 0.517 0.482
E13.1 With ketoacidosis
0.000 0.517 0.482
E13.0 With coma
0.000 0.517 0.482
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.520 0.480
E04 Other non-toxic goitre
0.000 0.521 0.479
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.521 0.479
M06.3 Rheumatoid nodule
0.000 0.523 0.477
E23 Hypofunction and other disorders of pituitary gland
0.000 0.523 0.477
E46 Unspecified protein-energy malnutrition
0.000 0.523 0.477
E13.9 Without complications
0.000 0.527 0.473
E61.1 Iron deficiency
0.000 0.529 0.471
K90.3 Pancreatic steatorrhoea
0.000 0.530 0.470
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.530 0.470
K90.1 Tropical sprue
0.000 0.530 0.470
M05.2 Rheumatoid vasculitis
0.000 0.530 0.469
E11.0 With coma
0.000 0.532 0.468
K90.8 Other intestinal malabsorption
0.000 0.538 0.462
C82.4 Follicular lymphoma grade IIIb
0.460 0.540 0.000
E28 Ovarian dysfunction
0.000 0.542 0.458
M14 Arthropathies in other diseases classified elsewhere
0.000 0.543 0.457
E54 Ascorbic acid deficiency
0.000 0.547 0.453
E13.3 With ophthalmic complications
0.000 0.550 0.450
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.550 0.449
J45.8 Mixed asthma
0.000 0.551 0.448
C82.6 Cutaneous follicle centre lymphoma
0.448 0.551 0.000
C82.5 Diffuse follicle centre lymphoma
0.448 0.551 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.553 0.447
J45.1 Nonallergic asthma
0.000 0.554 0.446
M11 Other crystal arthropathies
0.000 0.558 0.442
E24 Cushing's syndrome
0.000 0.560 0.440
M10 Gout
0.000 0.560 0.440
M34.1 CR(E)ST syndrome
0.000 0.562 0.438
M90 Osteopathies in diseases classified elsewhere
0.000 0.563 0.437
M22 Disorders of patella
0.000 0.564 0.436
C82.2 Large cell, follicular
0.432 0.568 0.000
L40.2 Acrodermatitis continua
0.431 0.569 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.569 0.431
M86.94 Osteomyelitis, unspecified (Hand)
0.000 0.570 0.430
E51 Thiamine deficiency
0.000 0.571 0.429
E23.2 Diabetes insipidus
0.000 0.571 0.429
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.572 0.428
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.572 0.428
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.572 0.428
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.572 0.428
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.572 0.428
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.572 0.428
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.572 0.428
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.572 0.428
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.573 0.427
E50 Vitamin A deficiency
0.000 0.573 0.427
E60 Dietary zinc deficiency
0.000 0.573 0.427
E59 Dietary selenium deficiency
0.000 0.573 0.427
E52 Niacin deficiency [pellagra]
0.000 0.573 0.427
E29 Testicular dysfunction
0.000 0.573 0.427
H36 Retinal disorders in diseases classified elsewhere
0.000 0.574 0.426
L40.8 Other psoriasis
0.425 0.575 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.575 0.425
E63 Other nutritional deficiencies
0.000 0.576 0.423
L40.4 Guttate psoriasis
0.423 0.577 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.578 0.422
M06.28 Rheumatoid bursitis (Other)
0.000 0.578 0.422
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.578 0.422
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.578 0.422
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.578 0.422
M06.24 Rheumatoid bursitis (Hand)
0.000 0.578 0.422
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.578 0.422
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.578 0.422
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.578 0.422
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.578 0.422
E53 Deficiency of other B group vitamins
0.000 0.579 0.421
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.579 0.421
M31 Other necrotising vasculopathies
0.000 0.581 0.419
M21 Other acquired deformities of limbs
0.000 0.581 0.419
M35.1 Other overlap syndromes
0.000 0.583 0.417
E28.3 Primary ovarian failure
0.000 0.584 0.416
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.586 0.414
M91-M94 Chondropathies
0.000 0.589 0.411
M34.8 Other forms of systemic sclerosis
0.000 0.590 0.410
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.592 0.408
E32 Diseases of thymus
0.000 0.592 0.408
E30 Disorders of puberty, not elsewhere classified
0.000 0.592 0.408
J41 Simple and mucopurulent chronic bronchitis
0.000 0.594 0.406
L40.3 Pustulosis palmaris et plantaris
0.405 0.594 0.000
M90.7 Fracture of bone in neoplastic disease
0.000 0.596 0.404
M12.3 Palindromic rheumatism
0.000 0.597 0.403
E04.0 Non-toxic diffuse goitre
0.000 0.599 0.401
J43.1 Panlobular emphysema
0.000 0.601 0.399
J43.0 MacLeod's syndrome
0.000 0.601 0.399
E07.1 Dyshormogenetic goitre
0.000 0.602 0.398
E07.0 Hypersecretion of calcitonin
0.000 0.602 0.398
M12.5 Traumatic arthropathy
0.000 0.603 0.396
M05.09 Felty's syndrome (Site unspecified)
0.000 0.605 0.394
M05.08 Felty's syndrome (Other)
0.000 0.605 0.394
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.605 0.394
M05.06 Felty's syndrome (Lower leg)
0.000 0.605 0.394
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.605 0.394
M05.04 Felty's syndrome (Hand)
0.000 0.605 0.394
M05.03 Felty's syndrome (Forearm)
0.000 0.605 0.394
M05.02 Felty's syndrome (Upper arm)
0.000 0.605 0.394
M05.01 Felty's syndrome (Shoulder region)
0.000 0.605 0.394
M05.00 Felty's syndrome (Multiple sites)
0.000 0.605 0.394
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.605 0.394
M05.18 Rheumatoid lung disease (Other)
0.000 0.605 0.394
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.605 0.394
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.605 0.394
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.605 0.394
M05.14 Rheumatoid lung disease (Hand)
0.000 0.605 0.394
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.605 0.394
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.605 0.394
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.605 0.394
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.605 0.394
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.605 0.394
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.605 0.394
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.605 0.394
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.605 0.394
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.605 0.394
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.605 0.394
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.605 0.394
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.605 0.394
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.605 0.394
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.605 0.394
M06.18 Adult-onset Still's disease (Other)
0.000 0.606 0.394
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.606 0.394
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.606 0.394
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.606 0.394
M06.14 Adult-onset Still's disease (Hand)
0.000 0.606 0.394
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.606 0.394
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.606 0.394
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.606 0.394
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.606 0.394
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.606 0.394
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.606 0.394
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.606 0.394
M09.0 Juvenile arthritis in psoriasis
0.000 0.606 0.394
M75 Shoulder lesions
0.000 0.607 0.393
M34.0 Progressive systemic sclerosis
0.000 0.607 0.393
E20 Hypoparathyroidism
0.000 0.608 0.392
E23.7 Disorder of pituitary gland, unspecified
0.000 0.608 0.392
M86.96 Osteomyelitis, unspecified (Lower leg)
0.000 0.608 0.392
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.609 0.391
M75.3 Calcific tendinitis of shoulder
0.000 0.611 0.389
M70-M79 Other soft tissue disorders
0.000 0.613 0.387
E25 Adrenogenital disorders
0.000 0.613 0.387
E07.8 Other specified disorders of thyroid
0.000 0.613 0.387
E56 Other vitamin deficiencies
0.001 0.615 0.385
M08.9 Juvenile arthritis, unspecified
0.000 0.618 0.382
M08.8 Other juvenile arthritis
0.000 0.618 0.382
M08.4 Pauciarticular juvenile arthritis
0.000 0.618 0.382
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.618 0.382
M08.2 Juvenile arthritis with systemic onset
0.000 0.618 0.382
M08.1 Juvenile ankylosing spondylitis
0.000 0.618 0.382
M35.8 Other specified systemic involvement of connective tissue
0.000 0.619 0.380
E31 Polyglandular dysfunction
0.000 0.620 0.380
M86.6 Other chronic osteomyelitis
0.000 0.620 0.380
M12.4 Intermittent hydrarthrosis
0.000 0.621 0.379
M12.1 Kaschin-Beck disease
0.000 0.621 0.379
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.621 0.379
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.000 0.622 0.378
M21.4 Flat foot [pes planus] (acquired)
0.000 0.623 0.377
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.626 0.374
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.627 0.373
E61.9 Deficiency of nutrient element, unspecified
0.000 0.627 0.372
E61.8 Deficiency of other specified nutrient elements
0.000 0.627 0.372
E61.7 Deficiency of multiple nutrient elements
0.000 0.627 0.372
E61.6 Vanadium deficiency
0.000 0.627 0.372
E61.5 Molybdenum deficiency
0.000 0.627 0.372
E61.4 Chromium deficiency
0.000 0.627 0.372
E61.3 Manganese deficiency
0.000 0.627 0.372
E61.0 Copper deficiency
0.000 0.627 0.372
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.628 0.372
M32.8 Other forms of systemic lupus erythematosus
0.000 0.628 0.372
E26 Hyperaldosteronism
0.000 0.629 0.371
E22 Hyperfunction of pituitary gland
0.000 0.629 0.371
C82.1 Mixed small cleaved and large cell, follicular
0.370 0.629 0.000
M86.8 Other osteomyelitis
0.000 0.631 0.369
M60-M63 Disorders of muscles
0.000 0.632 0.368
E23.6 Other disorders of pituitary gland
0.000 0.632 0.367
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.633 0.367
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.633 0.367
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.633 0.367
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.633 0.367
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.633 0.367
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.633 0.367
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.633 0.367
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.633 0.367
J43.8 Other emphysema
0.000 0.633 0.367
E27 Other disorders of adrenal gland
0.000 0.633 0.367
M34.9 Systemic sclerosis, unspecified
0.000 0.633 0.367
M08.0 Juvenile rheumatoid arthritis
0.000 0.633 0.366
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.635 0.365
M22.0 Recurrent dislocation of patella
0.000 0.636 0.364
M21.0 Valgus deformity, not elsewhere classified
0.000 0.637 0.363
M13 Other arthritis
0.000 0.639 0.361
M90.78 Fracture of bone in neoplastic disease (Other)
0.000 0.640 0.360
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.640 0.360
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.641 0.359
M75.9 Shoulder lesion, unspecified
0.000 0.642 0.358
E44.1 Mild protein-energy malnutrition
0.000 0.642 0.358
E44.0 Moderate protein-energy malnutrition
0.000 0.642 0.358
M35.2 Behcet's disease
0.000 0.643 0.357
M86.5 Other chronic haematogenous osteomyelitis
0.000 0.643 0.357
M86.3 Chronic multifocal osteomyelitis
0.000 0.643 0.357
M86.2 Subacute osteomyelitis
0.000 0.643 0.357
M86.0 Acute haematogenous osteomyelitis
0.000 0.643 0.357
M22.9 Disorder of patella, unspecified
0.000 0.643 0.357
M75.0 Adhesive capsulitis of shoulder
0.000 0.643 0.357
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.644 0.355
E61.2 Magnesium deficiency
0.000 0.646 0.354
M86.93 Osteomyelitis, unspecified (Forearm)
0.000 0.647 0.353
M86.92 Osteomyelitis, unspecified (Upper arm)
0.000 0.647 0.353
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.000 0.647 0.353
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.000 0.647 0.353
M86.1 Other acute osteomyelitis
0.000 0.648 0.352
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.000 0.648 0.352
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.648 0.351
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.648 0.351
M22.4 Chondromalacia patellae
0.000 0.648 0.352
M75.2 Bicipital tendinitis
0.000 0.649 0.351
M21.1 Varus deformity, not elsewhere classified
0.000 0.650 0.350
E24.2 Drug-induced Cushing's syndrome
0.000 0.650 0.349
J42 Unspecified chronic bronchitis
0.000 0.652 0.348
E27.1 Primary adrenocortical insufficiency
0.000 0.653 0.347
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.000 0.653 0.347
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.653 0.347
M10.0 Idiopathic gout
0.000 0.656 0.344
E04.8 Other specified non-toxic goitre
0.000 0.656 0.344
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.658 0.342
M06.38 Rheumatoid nodule (Other)
0.000 0.658 0.342
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.658 0.342
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.658 0.342
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.658 0.342
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.658 0.342
E23.1 Drug-induced hypopituitarism
0.000 0.658 0.342
M88 Paget's disease of bone [osteitis deformans]
0.000 0.659 0.341
M30 Polyarteritis nodosa and related conditions
0.000 0.660 0.340
E53.9 Vitamin B deficiency, unspecified
0.000 0.661 0.339
M05.28 Rheumatoid vasculitis (Other)
0.000 0.663 0.337
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.663 0.337
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.663 0.337
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.663 0.337
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.663 0.337
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.663 0.337
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.663 0.337
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.663 0.337
J43.2 Centrilobular emphysema
0.000 0.666 0.334
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.669 0.331
M75.4 Impingement syndrome of shoulder
0.000 0.671 0.329
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.000 0.672 0.328
E28.9 Ovarian dysfunction, unspecified
0.000 0.672 0.328
E28.8 Other ovarian dysfunction
0.000 0.672 0.328
E28.1 Androgen excess
0.000 0.672 0.328
E28.0 Oestrogen excess
0.000 0.672 0.328
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.672 0.328
M14.4 Arthropathy in amyloidosis
0.000 0.672 0.328
M14.3 Lipoid dermatoarthritis
0.000 0.672 0.328
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.672 0.328
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.672 0.328
M93 Other osteochondropathies
0.000 0.672 0.328
M90.70 Fracture of bone in neoplastic disease (Multiple sites)
0.000 0.673 0.327
M86.4 Chronic osteomyelitis with draining sinus
0.000 0.673 0.326
E29.1 Testicular hypofunction
0.000 0.674 0.326
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.675 0.324
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.000 0.677 0.323
E04.9 Non-toxic goitre, unspecified
0.000 0.677 0.323
M07 Psoriatic and enteropathic arthropathies
0.002 0.678 0.320
M89 Other disorders of bone
0.000 0.679 0.321
M14.6 Neuropathic arthropathy
0.000 0.680 0.320
M00-M03 Infectious arthropathies
0.000 0.680 0.320
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.000 0.680 0.320
M11.9 Crystal arthropathy, unspecified
0.000 0.682 0.318
M11.1 Familial chondrocalcinosis
0.000 0.683 0.317
M11.0 Hydroxyapatite deposition disease
0.000 0.683 0.317
M13.8 Other specified arthritis
0.000 0.683 0.317
E65-E68 Obesity and other hyperalimentation
0.000 0.684 0.316
E24.8 Other Cushing's syndrome
0.000 0.684 0.316
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.684 0.316
E24.3 Ectopic ACTH syndrome
0.000 0.684 0.316
E24.1 Nelson's syndrome
0.000 0.684 0.316
M10.4 Other secondary gout
0.000 0.684 0.315
M10.3 Gout due to impairment of renal function
0.000 0.684 0.315
M10.2 Drug-induced gout
0.000 0.684 0.315
M10.1 Lead-induced gout
0.000 0.684 0.315
E24.0 Pituitary-dependent Cushing's disease
0.000 0.685 0.315
E24.9 Cushing's syndrome, unspecified
0.000 0.685 0.315
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)
0.000 0.686 0.314
M94 Other disorders of cartilage
0.000 0.686 0.314
M90.8 Osteopathy in other diseases classified elsewhere
0.000 0.687 0.313
M90.5 Osteonecrosis in other diseases classified elsewhere
0.000 0.687 0.313
M90.4 Osteonecrosis due to heamoglobinopathy
0.000 0.687 0.313
M90.3 Osteonecrosis in caisson disease
0.000 0.687 0.313
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.000 0.687 0.313
M90.0 Tuberculosis of bone
0.000 0.687 0.313
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.000 0.687 0.313
M86.86 Other osteomyelitis (Lower leg)
0.000 0.687 0.313
M22.1 Recurrent subluxation of patella
0.000 0.688 0.312
M22.2 Patellofemoral disorders
0.000 0.689 0.311
M12.39 Palindromic rheumatism (Site unspecified)
0.000 0.689 0.310
E51.2 Wernicke's encephalopathy
0.000 0.690 0.310
M06.33 Rheumatoid nodule (Forearm)
0.000 0.691 0.309
M92 Other juvenile osteochondrosis
0.000 0.691 0.309
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.691 0.309
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.691 0.309
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.691 0.309

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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