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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs241458
log Bayes Factor = 122.511
Chromosome 6   position 32,888,566  (GRCh37) Explore rs241458 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.001 0.999
J45.9 Asthma, unspecified
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.001 0.999
M35.3 Polymyalgia rheumatica
0.000 0.003 0.997
E14 Unspecified diabetes mellitus
0.000 0.003 0.997
E10.2 With renal complications
0.000 0.010 0.990
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.014 0.986
E14.3 With ophthalmic complications
0.000 0.016 0.984
E10.8 With unspecified complications
0.000 0.017 0.983
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.018 0.982
E10.5 With peripheral circulatory complications
0.000 0.031 0.969
E10.0 With coma
0.000 0.037 0.963
H36.0 Diabetic retinopathy
0.000 0.047 0.953
J33.0 Polyp of nasal cavity
0.000 0.048 0.952
J33 Nasal polyp
0.000 0.059 0.941
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.061 0.939
M06 Other rheumatoid arthritis
0.000 0.065 0.935
J33.9 Nasal polyp, unspecified
0.000 0.070 0.930
E06 Thyroiditis
0.000 0.080 0.920
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.081 0.919
M05 Seropositive rheumatoid arthritis
0.000 0.083 0.917
M05-M14 Inflammatory polyarthropathies
0.000 0.083 0.917
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.085 0.915
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.102 0.898
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.107 0.893
E11 Non-insulin-dependent diabetes mellitus
0.000 0.110 0.890
E14.9 Without complications
0.000 0.111 0.889
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.115 0.885
J33.8 Other polyp of sinus
0.000 0.134 0.866
E10.6 With other specified complications
0.000 0.155 0.845
M35 Other systemic involvement of connective tissue
0.000 0.156 0.844
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.167 0.833
E14.8 With unspecified complications
0.000 0.184 0.816
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.187 0.813
E06.3 Autoimmune thyroiditis
0.000 0.189 0.811
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.202 0.798
E14.6 With other specified complications
0.000 0.204 0.796
E14.1 With ketoacidosis
0.000 0.207 0.793
E11.2 With renal complications
0.000 0.215 0.785
M20-M25 Other joint disorders
0.000 0.226 0.774
M06.4 Inflammatory polyarthropathy
0.000 0.230 0.770
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.235 0.765
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.238 0.762
E11.1 With ketoacidosis
0.000 0.240 0.760
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.240 0.760
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.755 0.245 0.000
M86-M90 Other osteopathies
0.000 0.263 0.737
E11.5 With peripheral circulatory complications
0.000 0.264 0.736
E06.9 Thyroiditis, unspecified
0.000 0.265 0.735
J33.1 Polypoid sinus degeneration
0.000 0.272 0.728
E03.1 Congenital hypothyroidism without goitre
0.000 0.274 0.726
M86 Osteomyelitis
0.000 0.277 0.723
E06.5 Other chronic thyroiditis
0.000 0.282 0.718
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.285 0.715
E14.7 With multiple complications
0.000 0.285 0.715
E14.0 With coma
0.000 0.285 0.715
M34 Systemic sclerosis
0.000 0.287 0.713
M05.8 Other seropositive rheumatoid arthritis
0.000 0.287 0.712
M86.9 Osteomyelitis, unspecified
0.000 0.288 0.712
E40-E46 Malnutrition
0.000 0.288 0.712
E11.6 With other specified complications
0.000 0.289 0.711
M32 Systemic lupus erythematosus
0.000 0.291 0.709
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.299 0.700
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.303 0.697
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.000 0.304 0.696
E11.3 With ophthalmic complications
0.000 0.308 0.692
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.312 0.688
E03.8 Other specified hypothyroidism
0.000 0.312 0.688
J45 Asthma
0.000 0.317 0.683
M35.7 Hypermobility syndrome
0.000 0.318 0.682
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.322 0.678
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.327 0.673
E06.1 Subacute thyroiditis
0.000 0.327 0.673
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.328 0.672
K90 Intestinal malabsorption
0.000 0.330 0.670
M06.2 Rheumatoid bursitis
0.000 0.330 0.670
E13 Other specified diabetes mellitus
0.000 0.330 0.670
E14.2 Withrenal complications
0.000 0.338 0.662
E06.4 Drug-induced thyroiditis
0.000 0.340 0.660
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.340 0.660
E06.0 Acute thyroiditis
0.000 0.340 0.660
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.341 0.659
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.342 0.657
M05.1 Rheumatoid lung disease
0.000 0.342 0.657
M05.0 Felty's syndrome
0.000 0.342 0.657
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.343 0.657
M35.0 Sicca syndrome [Sjogren]
0.000 0.344 0.656
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.346 0.654
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.349 0.651
E14.4 With neurological complications
0.000 0.354 0.646
M90 Osteopathies in diseases classified elsewhere
0.000 0.357 0.642
M12 Other specific arthropathies
0.000 0.360 0.640
M21 Other acquired deformities of limbs
0.000 0.361 0.639
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.639 0.361 0.000
E11.7 With multiple complications
0.000 0.362 0.638
M08 Juvenile arthritis
0.000 0.362 0.638
E11.9 Without complications
0.000 0.363 0.637
M75 Shoulder lesions
0.000 0.372 0.628
M06.1 Adult-onset Still's disease
0.000 0.374 0.626
M70-M79 Other soft tissue disorders
0.000 0.375 0.625
M75.3 Calcific tendinitis of shoulder
0.000 0.376 0.624
M34.1 CR(E)ST syndrome
0.000 0.378 0.622
E05.8 Other thyrotoxicosis
0.000 0.388 0.612
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.394 0.606
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.395 0.605
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.395 0.605
M35.5 Multifocal fibrosclerosis
0.000 0.395 0.605
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.395 0.605
M31 Other necrotising vasculopathies
0.000 0.396 0.604
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.397 0.603
M90.7 Fracture of bone in neoplastic disease
0.000 0.401 0.599
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.408 0.592
M86.94 Osteomyelitis, unspecified (Hand)
0.000 0.408 0.592
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.408 0.592
C82.0 Small cleaved cell, follicular
0.592 0.408 0.000
M22 Disorders of patella
0.000 0.412 0.588
M06.8 Other specified rheumatoid arthritis
0.000 0.417 0.583
E50-E64 Other nutritional deficiencies
0.000 0.417 0.583
M34.8 Other forms of systemic sclerosis
0.000 0.418 0.582
M75.0 Adhesive capsulitis of shoulder
0.000 0.425 0.575
M21.4 Flat foot [pes planus] (acquired)
0.000 0.426 0.574
L40.9 Psoriasis, unspecified
0.573 0.427 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.428 0.572
M91-M94 Chondropathies
0.000 0.429 0.571
M21.0 Valgus deformity, not elsewhere classified
0.000 0.432 0.568
J40-J47 Chronic lower respiratory diseases
0.000 0.432 0.568
K90.9 Intestinal malabsorption, unspecified
0.000 0.433 0.567
M86.96 Osteomyelitis, unspecified (Lower leg)
0.000 0.434 0.566
M14 Arthropathies in other diseases classified elsewhere
0.000 0.434 0.566
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.436 0.564
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.000 0.437 0.563
J44 Other chronic obstructive pulmonary disease
0.000 0.437 0.563
M75.9 Shoulder lesion, unspecified
0.000 0.438 0.562
M05.2 Rheumatoid vasculitis
0.000 0.439 0.561
M11 Other crystal arthropathies
0.000 0.440 0.560
M34.0 Progressive systemic sclerosis
0.000 0.441 0.558
M06.3 Rheumatoid nodule
0.000 0.442 0.558
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.443 0.557
M86.8 Other osteomyelitis
0.000 0.448 0.552
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.448 0.552
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.448 0.552
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.448 0.552
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.448 0.552
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.448 0.552
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.448 0.552
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.448 0.552
M86.6 Other chronic osteomyelitis
0.000 0.450 0.550
M75.2 Bicipital tendinitis
0.000 0.450 0.550
E07 Other disorders of thyroid
0.000 0.450 0.550
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.452 0.548
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.000 0.454 0.546
M35.1 Other overlap syndromes
0.000 0.454 0.546
C82.3 Follicular lymphoma grade IIIa
0.543 0.457 0.000
J43 Emphysema
0.000 0.459 0.541
M60-M63 Disorders of muscles
0.000 0.459 0.541
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.460 0.540
M32.8 Other forms of systemic lupus erythematosus
0.000 0.463 0.537
E11.8 With unspecified complications
0.000 0.463 0.537
M90.78 Fracture of bone in neoplastic disease (Other)
0.000 0.468 0.532
J43.9 Emphysema, unspecified
0.000 0.470 0.530
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.000 0.472 0.528
M10 Gout
0.000 0.477 0.523
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.000 0.479 0.521
M75.4 Impingement syndrome of shoulder
0.000 0.480 0.520
M21.1 Varus deformity, not elsewhere classified
0.000 0.481 0.519
M86.5 Other chronic haematogenous osteomyelitis
0.000 0.481 0.519
M86.3 Chronic multifocal osteomyelitis
0.000 0.481 0.519
M86.2 Subacute osteomyelitis
0.000 0.481 0.519
M86.0 Acute haematogenous osteomyelitis
0.000 0.481 0.519
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.481 0.519
M34.9 Systemic sclerosis, unspecified
0.000 0.482 0.518
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.514 0.486 0.000
E16.1 Other hypoglycaemia
0.000 0.486 0.513
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.489 0.511
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.489 0.511
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.489 0.511
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.489 0.511
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.489 0.511
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.489 0.511
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.489 0.511
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.489 0.511
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.489 0.511
M86.93 Osteomyelitis, unspecified (Forearm)
0.000 0.489 0.511
M86.92 Osteomyelitis, unspecified (Upper arm)
0.000 0.489 0.511
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.000 0.489 0.511
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.000 0.489 0.511
M86.1 Other acute osteomyelitis
0.000 0.489 0.511
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.489 0.510
E45 Retarded development following protein-energy malnutrition
0.000 0.489 0.510
E43 Unspecified severe protein-energy malnutrition
0.000 0.489 0.510
E42 Marasmic kwashiorkor
0.000 0.489 0.510
E41 Nutritional marasmus
0.000 0.489 0.510
E40 Kwashiorkor
0.000 0.489 0.510
M88 Paget's disease of bone [osteitis deformans]
0.000 0.490 0.510
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.000 0.491 0.508
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.492 0.508
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.492 0.508
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.494 0.505
E46 Unspecified protein-energy malnutrition
0.000 0.494 0.506
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.497 0.503
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.498 0.502
M35.8 Other specified systemic involvement of connective tissue
0.000 0.498 0.501
E61 Deficiency of other nutrient elements
0.000 0.503 0.497
M22.0 Recurrent dislocation of patella
0.000 0.509 0.491
J45.0 Predominantly allergic asthma
0.000 0.509 0.491
M12.3 Palindromic rheumatism
0.000 0.512 0.488
M40-M43 Deforming dorsopathies
0.000 0.513 0.487
M90.70 Fracture of bone in neoplastic disease (Multiple sites)
0.000 0.515 0.484
M30 Polyarteritis nodosa and related conditions
0.000 0.516 0.483
M22.9 Disorder of patella, unspecified
0.000 0.518 0.482
K90.3 Pancreatic steatorrhoea
0.000 0.519 0.481
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.519 0.481
K90.1 Tropical sprue
0.000 0.519 0.481
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.519 0.480
M06.28 Rheumatoid bursitis (Other)
0.000 0.519 0.480
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.519 0.480
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.519 0.480
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.519 0.480
M06.24 Rheumatoid bursitis (Hand)
0.000 0.519 0.480
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.519 0.480
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.519 0.480
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.519 0.480
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.519 0.480
E13.8 With unspecified complications
0.000 0.519 0.480
E13.7 With multiple complications
0.000 0.519 0.480
E13.6 With other specified complications
0.000 0.519 0.480
E13.5 With peripheral circulatory complications
0.000 0.519 0.480
E13.4 With neurological complications
0.000 0.519 0.480
E13.2 With renal complications
0.000 0.519 0.480
E13.1 With ketoacidosis
0.000 0.519 0.480
E13.0 With coma
0.000 0.519 0.480
M12.5 Traumatic arthropathy
0.000 0.519 0.481
M86.86 Other osteomyelitis (Lower leg)
0.000 0.521 0.479
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)
0.000 0.521 0.479
M86.4 Chronic osteomyelitis with draining sinus
0.000 0.526 0.474
K90.8 Other intestinal malabsorption
0.000 0.528 0.472
M05.09 Felty's syndrome (Site unspecified)
0.000 0.528 0.471
M05.08 Felty's syndrome (Other)
0.000 0.528 0.471
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.528 0.471
M05.06 Felty's syndrome (Lower leg)
0.000 0.528 0.471
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.528 0.471
M05.04 Felty's syndrome (Hand)
0.000 0.528 0.471
M05.03 Felty's syndrome (Forearm)
0.000 0.528 0.471
M05.02 Felty's syndrome (Upper arm)
0.000 0.528 0.471
M05.01 Felty's syndrome (Shoulder region)
0.000 0.528 0.471
M05.00 Felty's syndrome (Multiple sites)
0.000 0.528 0.471
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.528 0.471
M05.18 Rheumatoid lung disease (Other)
0.000 0.528 0.471
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.528 0.471
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.528 0.471
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.528 0.471
M05.14 Rheumatoid lung disease (Hand)
0.000 0.528 0.471
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.528 0.471
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.528 0.471
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.528 0.471
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.528 0.471
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.528 0.471
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.528 0.471
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.528 0.471
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.528 0.471
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.528 0.471
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.528 0.471
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.528 0.471
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.528 0.471
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.528 0.471
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.528 0.471
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.529 0.471
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.529 0.471
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.529 0.471
M09.0 Juvenile arthritis in psoriasis
0.000 0.529 0.471
C82.4 Follicular lymphoma grade IIIb
0.470 0.530 0.000
E13.9 Without complications
0.000 0.532 0.468
E20-E35 Disorders of other endocrine glands
0.000 0.534 0.466
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.000 0.535 0.465
E11.0 With coma
0.000 0.537 0.462
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.000 0.539 0.461
M90.8 Osteopathy in other diseases classified elsewhere
0.000 0.539 0.461
M90.5 Osteonecrosis in other diseases classified elsewhere
0.000 0.539 0.461
M90.4 Osteonecrosis due to heamoglobinopathy
0.000 0.539 0.461
M90.3 Osteonecrosis in caisson disease
0.000 0.539 0.461
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.000 0.539 0.461
M90.0 Tuberculosis of bone
0.000 0.539 0.461
M13 Other arthritis
0.000 0.540 0.460
M12.4 Intermittent hydrarthrosis
0.000 0.541 0.459
M12.1 Kaschin-Beck disease
0.000 0.541 0.459
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.541 0.459
M22.4 Chondromalacia patellae
0.000 0.541 0.459
M70.4 Prepatellar bursitis
0.000 0.542 0.458
C82.6 Cutaneous follicle centre lymphoma
0.458 0.542 0.000
C82.5 Diffuse follicle centre lymphoma
0.458 0.542 0.000
M08.9 Juvenile arthritis, unspecified
0.000 0.542 0.457
M08.8 Other juvenile arthritis
0.000 0.542 0.457
M08.4 Pauciarticular juvenile arthritis
0.000 0.542 0.457
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.542 0.457
M08.2 Juvenile arthritis with systemic onset
0.000 0.542 0.457
M08.1 Juvenile ankylosing spondylitis
0.000 0.542 0.457
M70.2 Olecranon bursitis
0.000 0.542 0.458
M21.6 Other acquired deformities of ankle and foot
0.000 0.545 0.455
M00-M03 Infectious arthropathies
0.000 0.545 0.455
M86.67 Other chronic osteomyelitis (Ankle and foot)
0.000 0.547 0.453
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.548 0.452
M90.71 Fracture of bone in neoplastic disease (Shoulder region)
0.000 0.550 0.450
M06.18 Adult-onset Still's disease (Other)
0.000 0.551 0.449
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.551 0.449
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.551 0.449
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.551 0.449
M06.14 Adult-onset Still's disease (Hand)
0.000 0.551 0.449
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.551 0.449
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.551 0.449
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.551 0.449
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.551 0.449
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.552 0.448
E13.3 With ophthalmic complications
0.000 0.552 0.448
E11.4 With neurological complications
0.000 0.553 0.447
M60 Myositis
0.000 0.553 0.447
M35.2 Behcet's disease
0.000 0.554 0.446
M89 Other disorders of bone
0.000 0.554 0.446
M21.9 Acquired deformity of limb, unspecified
0.000 0.554 0.446
M06.0 Seronegative rheumatoid arthritis
0.000 0.555 0.444
E54 Ascorbic acid deficiency
0.000 0.556 0.443
M93 Other osteochondropathies
0.000 0.556 0.443
E61.1 Iron deficiency
0.000 0.557 0.443
M90.6 Osteitis deformans in neoplastic disease
0.000 0.558 0.442
M75.8 Other shoulder lesions
0.000 0.558 0.442
C82.2 Large cell, follicular
0.442 0.558 0.000
M31.7 Microscopic polyangiitis
0.000 0.560 0.440
M08.0 Juvenile rheumatoid arthritis
0.000 0.561 0.438
M31.6 Other giant cell arteritis
0.000 0.562 0.438
M86.98 Osteomyelitis, unspecified (Other)
0.000 0.563 0.437
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.565 0.434
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.566 0.434
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.567 0.433
M31.2 Lethal midline granuloma
0.000 0.567 0.433
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.000 0.568 0.432
J45.1 Nonallergic asthma
0.000 0.568 0.432
H36 Retinal disorders in diseases classified elsewhere
0.000 0.570 0.430
M90.79 Fracture of bone in neoplastic disease (Site unspecified)
0.000 0.571 0.429
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)
0.000 0.571 0.429
M90.76 Fracture of bone in neoplastic disease (Lower leg)
0.000 0.571 0.429
M90.74 Fracture of bone in neoplastic disease (Hand)
0.000 0.571 0.429
M90.73 Fracture of bone in neoplastic disease (Forearm)
0.000 0.571 0.429
M92 Other juvenile osteochondrosis
0.000 0.571 0.429
L40 Psoriasis
0.427 0.572 0.000
E53 Deficiency of other B group vitamins
0.000 0.573 0.427
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.574 0.426
M21.8 Other specified acquired deformities of limbs
0.000 0.575 0.425
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.000 0.576 0.424
M36.3 Arthropathy in other blood disorders
0.000 0.576 0.424
M36.2 Haemophilic arthropathy
0.000 0.576 0.424
M36.1 Arthropathy in neoplastic disease
0.000 0.576 0.424
M36.0 Dermato(poly)myositis in neoplastic disease
0.000 0.576 0.424
M94 Other disorders of cartilage
0.000 0.576 0.424
M31.8 Other specified necrotising vasculopathies
0.000 0.576 0.424
M22.1 Recurrent subluxation of patella
0.000 0.578 0.422
E51 Thiamine deficiency
0.000 0.580 0.420
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.580 0.420
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.582 0.418
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.582 0.418
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.582 0.418
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.582 0.418
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.582 0.418
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.582 0.418
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.582 0.418
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.582 0.418
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.582 0.418
E50 Vitamin A deficiency
0.000 0.582 0.418
E60 Dietary zinc deficiency
0.000 0.582 0.418
E59 Dietary selenium deficiency
0.000 0.582 0.418
E52 Niacin deficiency [pellagra]
0.000 0.582 0.418
E04 Other non-toxic goitre
0.000 0.582 0.418
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.585 0.415
E63 Other nutritional deficiencies
0.000 0.585 0.414
M11.9 Crystal arthropathy, unspecified
0.000 0.586 0.414
M21.49 Flat foot [pes planus] (acquired)-Site unspec
0.000 0.588 0.412
M21.48 Flat foot [pes planus] (acquired)-Other
0.000 0.588 0.412
M21.46 Flat foot [pes planus] (acquired)-Lower leg
0.000 0.588 0.412
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh
0.000 0.588 0.412
M21.44 Flat foot [pes planus] (acquired)-Hand
0.000 0.588 0.412
M21.43 Flat foot [pes planus] (acquired)-Forearm
0.000 0.588 0.412
M21.42 Flat foot [pes planus] (acquired)-Upper arm
0.000 0.588 0.412
M21.41 Flat foot [pes planus] (acquired)-Shldr region
0.000 0.588 0.412
M21.40 Flat foot [pes planus] (acquired)-Mult sites
0.000 0.588 0.412
J42 Unspecified chronic bronchitis
0.000 0.588 0.412
M70.22 Olecranon bursitis-Upper arm
0.000 0.588 0.411
M14.6 Neuropathic arthropathy
0.000 0.590 0.410
M13.8 Other specified arthritis
0.000 0.590 0.410
M10.0 Idiopathic gout
0.000 0.592 0.408
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)
0.000 0.592 0.407
M21.08 Valgus deformity, not elsewhere classified (Other)
0.000 0.592 0.407
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)
0.000 0.592 0.407
M21.04 Valgus deformity, not elsewhere classified (Hand)
0.000 0.592 0.407
M21.03 Valgus deformity, not elsewhere classified (Forearm)
0.000 0.592 0.407
M21.02 Valgus deformity, not elsewhere classified (Upper arm)
0.000 0.592 0.407
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)
0.000 0.592 0.407
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)
0.000 0.592 0.407
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.594 0.406
M14.4 Arthropathy in amyloidosis
0.000 0.594 0.406
M14.3 Lipoid dermatoarthritis
0.000 0.594 0.406
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.594 0.406
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.594 0.406
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.595 0.405
M90.72 Fracture of bone in neoplastic disease (Upper arm)
0.000 0.595 0.405
L40.5 Arthropathic psoriasis
0.404 0.596 0.000
M05.28 Rheumatoid vasculitis (Other)
0.000 0.598 0.402
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.598 0.402
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.598 0.402
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.598 0.402
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.598 0.402
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.598 0.402
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.598 0.402
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.598 0.402
M11.1 Familial chondrocalcinosis
0.000 0.598 0.402
M11.0 Hydroxyapatite deposition disease
0.000 0.598 0.402
M31.0 Hypersensitivity angiitis
0.000 0.598 0.402
M22.2 Patellofemoral disorders
0.000 0.598 0.402
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.599 0.401
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.600 0.400
M06.38 Rheumatoid nodule (Other)
0.000 0.600 0.400
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.600 0.400
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.600 0.400
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.600 0.400
M31.9 Necrotising vasculopathy, unspecified
0.000 0.601 0.399
C82.1 Mixed small cleaved and large cell, follicular
0.398 0.601 0.000
M86.89 Other osteomyelitis (Site unspecified)
0.000 0.604 0.396
M86.88 Other osteomyelitis (Other)
0.000 0.604 0.396
M86.84 Other osteomyelitis (Hand)
0.000 0.604 0.396
M86.83 Other osteomyelitis (Forearm)
0.000 0.604 0.396
M86.82 Other osteomyelitis (Upper arm)
0.000 0.604 0.396
M86.81 Other osteomyelitis (Shoulder region)
0.000 0.604 0.396
M86.80 Other osteomyelitis (Multiple sites)
0.000 0.604 0.396
J41 Simple and mucopurulent chronic bronchitis
0.000 0.604 0.396
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.000 0.605 0.395
M86.69 Other chronic osteomyelitis (Site unspecified)
0.000 0.605 0.395
M86.68 Other chronic osteomyelitis (Other)
0.000 0.605 0.395
M86.64 Other chronic osteomyelitis (Hand)
0.000 0.605 0.395
M86.63 Other chronic osteomyelitis (Forearm)
0.000 0.605 0.395
M86.62 Other chronic osteomyelitis (Upper arm)
0.000 0.605 0.395
M86.61 Other chronic osteomyelitis (Shoulder region)
0.000 0.605 0.395
M86.60 Other chronic osteomyelitis (Multiple sites)
0.000 0.605 0.395
E07.1 Dyshormogenetic goitre
0.000 0.606 0.394
E07.0 Hypersecretion of calcitonin
0.000 0.606 0.394
J45.8 Mixed asthma
0.000 0.609 0.391
M89.8 Other specified disorders of bone
0.000 0.609 0.391
M90.1 Periostitis in other infectious diseases classified elsewhere
0.000 0.611 0.388
J43.1 Panlobular emphysema
0.000 0.612 0.388
J43.0 MacLeod's syndrome
0.000 0.612 0.388
M63 Disorders of muscle in diseases classified elsewhere
0.000 0.612 0.388
M61 Calcification and ossification of muscle
0.000 0.612 0.388

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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