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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2417373
log Bayes Factor = 14.5305
Chromosome 12   position 14,744,468  (GRCh37) Explore rs2417373 on Ensembl!
Variant rs2417373 is part of Cluster X0164

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.998 0.002 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.994 0.006 0.000
M45-M49 Spondylopathies
0.994 0.006 0.000
Chapter XI Diseases of the digestive system
0.994 0.006 0.000
K55-K64 Other diseases of intestines
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.991 0.009 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.988 0.012 0.000
M47 Spondylosis
0.981 0.019 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.981 0.019 0.000
L60-L75 Disorders of skin appendages
0.979 0.021 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.977 0.023 0.000
Y83.6 Removal of other organ (partial) (total)
0.975 0.025 0.000
Chapter XIV Diseases of the genitourinary system
0.967 0.033 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.960 0.040 0.000
E78.0 Pure hypercholesterolaemia
0.955 0.045 0.000
Chapter V Mental and behavioural disorders
0.955 0.045 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.953 0.047 0.000
E10-E14 Diabetes mellitus
0.950 0.050 0.000
K63 Other diseases of intestine
0.948 0.052 0.000
M47.9 Spondylosis, unspecified
0.947 0.053 0.000
N30-N39 Other diseases of urinary system
0.944 0.056 0.000
Y83.4 Other reconstructive surgery
0.937 0.063 0.000
E11 Non-insulin-dependent diabetes mellitus
0.937 0.063 0.000
N39 Other disorders of urinary system
0.936 0.064 0.000
K59 Other functional intestinal disorders
0.928 0.072 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.926 0.074 0.000
M48 Other spondylopathies
0.924 0.076 0.000
E11.9 Without complications
0.920 0.080 0.000
A30-A49 Other bacterial diseases
0.919 0.081 0.000
E83 Disorders of mineral metabolism
0.914 0.086 0.000
L72.1 Trichilemmal cyst
0.914 0.086 0.000
N39.4 Other specified urinary incontinence
0.912 0.088 0.000
T81 Complications of procedures, not elsewhere classified
0.910 0.090 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.902 0.098 0.000
S00-S09 Injuries to the head
0.901 0.099 0.000
Chapter X Diseases of the respiratory system
0.901 0.099 0.000
Chapter VI Diseases of the nervous system
0.901 0.099 0.000
E20-E35 Disorders of other endocrine glands
0.897 0.103 0.000
L89 Decubitus ulcer
0.895 0.105 0.000
K63.8 Other specified diseases of intestine
0.895 0.105 0.000
M15-M19 Arthrosis
0.893 0.107 0.000
K58 Irritable bowel syndrome
0.890 0.110 0.000
M47.8 Other spondylosis
0.890 0.110 0.000
N39.3 Stress incontinence
0.889 0.111 0.000
E83.5 Disorders of calcium metabolism
0.886 0.114 0.000
M70-M79 Other soft tissue disorders
0.882 0.118 0.000
B95-B98 Bacterial, viral and other infectious agents
0.879 0.121 0.000
Chapter II Neoplasms
0.878 0.122 0.000
K70-K77 Diseases of liver
0.877 0.123 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.876 0.124 0.000
K57 Diverticular disease of intestine
0.876 0.124 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.874 0.126 0.000
E86 Volume depletion
0.874 0.126 0.000
M48.0 Spinal stenosis
0.874 0.126 0.000
M17 Gonarthrosis [arthrosis of knee]
0.871 0.129 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.870 0.130 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.870 0.130 0.000
B15-B19 Viral hepatitis
0.867 0.133 0.000
K90-K93 Other diseases of the digestive system
0.867 0.133 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.864 0.136 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.862 0.138 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.862 0.138 0.000
N99-N99 Other disorders of the genitourinary system
0.857 0.143 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.857 0.143 0.000
M17.1 Other primary gonarthrosis
0.856 0.144 0.000
K59.0 Constipation
0.855 0.145 0.000
L72.0 Epidermal cyst
0.852 0.148 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.850 0.150 0.000
A41 Other septicaemia
0.848 0.152 0.000
M40-M43 Deforming dorsopathies
0.848 0.152 0.000
Chapter VIII Diseases of the ear and mastoid process
0.846 0.154 0.000
J30-J39 Other diseases of upper respiratory tract
0.842 0.158 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.840 0.160 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.838 0.162 0.000
N88 Other noninflammatory disorders of cervix uteri
0.836 0.164 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.834 0.166 0.000
S40-S49 Injuries to the shoulder and upper arm
0.830 0.170 0.000
E78.2 Mixed hyperlipidaemia
0.826 0.174 0.000
K62 Other diseases of anus and rectum
0.824 0.176 0.000
Chapter XXI Factors influencing health status and contact with health services
0.823 0.177 0.000
K60 Fissure and fistula of anal and rectal regions
0.821 0.179 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.821 0.179 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.820 0.180 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.819 0.181 0.000
W00-W19 Falls
0.819 0.181 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.817 0.183 0.000
J20-J22 Other acute lower respiratory infections
0.816 0.184 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.812 0.188 0.000
A41.9 Septicaemia, unspecified
0.811 0.189 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.809 0.191 0.000
K63.9 Disease of intestine, unspecified
0.807 0.193 0.000
A00-A09 Intestinal infectious diseases
0.806 0.194 0.000
Chapter XXII Codes for special purposes
0.805 0.195 0.000
L89.1 Stage II decubitus ulcer
0.803 0.197 0.000
E27 Other disorders of adrenal gland
0.803 0.197 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.802 0.198 0.000
N92 Excessive, frequent and irregular menstruation
0.802 0.198 0.000
K63.2 Fistula of intestine
0.802 0.198 0.000
L60 Nail disorders
0.798 0.202 0.000
B35-B49 Mycoses
0.794 0.206 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.791 0.209 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.790 0.210 0.000
M17.0 Primary gonarthrosis, bilateral
0.789 0.211 0.000
S00 Superficial injury of head
0.788 0.212 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.788 0.212 0.000
D10-D36 Benign neoplasms
0.788 0.212 0.000
E11.5 With peripheral circulatory complications
0.785 0.215 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.785 0.215 0.000
E78.5 Hyperlipidaemia, unspecified
0.784 0.216 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.783 0.217 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.782 0.218 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.781 0.219 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.781 0.219 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.779 0.221 0.000
S70-S79 Injuries to the hip and thigh
0.777 0.223 0.000
F10.1 Harmful use
0.775 0.225 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.773 0.227 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.773 0.227 0.000
N34 Urethritis and urethral syndrome
0.773 0.227 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.772 0.228 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.771 0.229 0.000
X20-X29 Contact with venomous animals and plants
0.770 0.230 0.000
K62.3 Rectal prolapse
0.770 0.230 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.769 0.231 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.769 0.231 0.000
H65-H75 Diseases of middle ear and mastoid
0.767 0.233 0.000
F10.2 Dependence syndrome
0.764 0.236 0.000
L91 Hypertrophic disorders of skin
0.762 0.237 0.000
G30-G32 Other degenerative diseases of the nervous system
0.762 0.237 0.000
K13 Other diseases of lip and oral mucosa
0.762 0.238 0.000
N80 Endometriosis
0.761 0.238 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.761 0.239 0.000
M60-M63 Disorders of muscles
0.760 0.240 0.000
M80-M85 Disorders of bone density and structure
0.760 0.240 0.000
M86-M90 Other osteopathies
0.759 0.241 0.000
Z98 Other postsurgical states
0.759 0.241 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.759 0.241 0.000
N92.3 Ovulation bleeding
0.759 0.241 0.000
K75 Other inflammatory liver diseases
0.759 0.241 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.758 0.242 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.757 0.243 0.000
J32 Chronic sinusitis
0.756 0.244 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.756 0.244 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.756 0.244 0.000
E40-E46 Malnutrition
0.755 0.245 0.000
E11.6 With other specified complications
0.754 0.246 0.000
M47.2 Other spondylosis with radiculopathy
0.753 0.247 0.000
J34 Other disorders of nose and nasal sinuses
0.752 0.248 0.000
L50-L54 Urticaria and erythema
0.750 0.249 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.750 0.250 0.000
F30-F39 Mood [affective] disorders
0.748 0.252 0.000
M48.06 Spinal stenosis (Lumbar region)
0.747 0.253 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.746 0.254 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.746 0.254 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.745 0.255 0.000
Z88.0 Personal history of allergy to penicillin
0.745 0.255 0.000
M48.09 Spinal stenosis (Site unspecified)
0.745 0.255 0.000
D50-D53 Nutritional anaemias
0.745 0.255 0.000
M91-M94 Chondropathies
0.744 0.256 0.000
J22 Unspecified acute lower respiratory infection
0.744 0.256 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.744 0.256 0.000
L71 Rosacea
0.743 0.256 0.000
B25-B34 Other viral diseases
0.743 0.257 0.000
Y95 Nosocomial condition
0.743 0.257 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.742 0.258 0.000
F17.1 Harmful use
0.742 0.258 0.000
M43 Other deforming dorsopathies
0.741 0.259 0.000
F80-F89 Disorders of psychological development
0.741 0.259 0.000
K12 Stomatitis and related lesions
0.741 0.259 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.741 0.259 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.741 0.259 0.000
N10-N16 Renal tubulo-interstitial diseases
0.739 0.261 0.000
E65-E68 Obesity and other hyperalimentation
0.739 0.261 0.000
S10-S19 Injuries to the neck
0.739 0.261 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.739 0.261 0.000
T79-T79 Certain early complications of trauma
0.738 0.262 0.000
E13 Other specified diabetes mellitus
0.737 0.263 0.000
K62.1 Rectal polyp
0.735 0.265 0.000
N73 Other female pelvic inflammatory diseases
0.735 0.265 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.733 0.267 0.000
V20-V29 Motorcycle rider injured in transport accident
0.731 0.269 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.730 0.270 0.000
X60-X84 Intentional self-harm
0.730 0.270 0.000
N80.0 Endometriosis of uterus
0.730 0.270 0.000
A49 Bacterial infection of unspecified site
0.730 0.270 0.000
F10.4 Withdrawal state with delirium
0.730 0.270 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.730 0.270 0.000
L85 Other epidermal thickening
0.730 0.270 0.000
D22 Melanocytic naevi
0.728 0.272 0.000
S09 Other and unspecified injuries of head
0.727 0.273 0.000
Y83.9 Surgical procedure, unspecified
0.726 0.274 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.726 0.274 0.000
N39.0 Urinary tract infection, site not specified
0.726 0.274 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.726 0.274 0.000
K11 Diseases of salivary glands
0.722 0.278 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.721 0.278 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.720 0.280 0.000
T66-T78 Other and unspecified effects of external causes
0.719 0.281 0.000
C15-C26 Malignant neoplasms of digestive organs
0.719 0.281 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.718 0.282 0.000
E27.1 Primary adrenocortical insufficiency
0.718 0.282 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.718 0.282 0.000
N85.4 Malposition of uterus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D00-D09 In situ neoplasms
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.283 0.000
Y10-Y34 Event of undetermined intent
0.716 0.283 0.000
Y00-Y09 Assault
0.716 0.283 0.000
X85-X99 Assault
0.716 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.283 0.000
X50-X57 Overexertion, travel and privation
0.716 0.283 0.000
X30-X39 Exposure to forces of nature
0.716 0.283 0.000
X10-X19 Contact with heat and hot substances
0.716 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.283 0.000
W75-W84 Other accidental threats to breathing
0.716 0.283 0.000
W65-W74 Accidental drowning and submersion
0.716 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.283 0.000
V95-V97 Air and space transport accidents
0.716 0.283 0.000
V90-V94 Water transport accidents
0.716 0.283 0.000
V80-V89 Other land transport accidents
0.716 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.716 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
K59.8 Other specified functional intestinal disorders
0.716 0.284 0.000
K08 Other disorders of teeth and supporting structures
0.716 0.284 0.000
Y83.5 Amputation of limb(s)
0.715 0.284 0.000
E85 Amyloidosis
0.715 0.285 0.000
E84 Cystic fibrosis
0.715 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E74 Other disorders of carbohydrate metabolism
0.715 0.285 0.000
E73 Lactose intolerance
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.714 0.286 0.000
T81.9 Unspecified complication of procedure
0.714 0.286 0.000
Y83.0 Surgical operation with transplant of whole organ
0.713 0.287 0.000
L10-L14 Bullous disorders
0.713 0.287 0.000
M49 Spondylopathies in diseases classified elsewhere
0.713 0.287 0.000
S06 Intracranial injury
0.712 0.287 0.000
N00-N08 Glomerular diseases
0.712 0.288 0.000
S90-S99 Injuries to the ankle and foot
0.712 0.288 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.712 0.288 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.711 0.289 0.000
S20-S29 Injuries to the thorax
0.711 0.289 0.000
B99-B99 Other infectious diseases
0.711 0.289 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.711 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.711 0.289 0.000
B65-B83 Helminthiases
0.711 0.289 0.000
B50-B64 Protozoal diseases
0.711 0.289 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.711 0.289 0.000
A75-A79 Rickettsioses
0.711 0.289 0.000
A70-A74 Other diseases caused by chlamydiae
0.711 0.289 0.000
A65-A69 Other spirochaetal diseases
0.711 0.289 0.000
A20-A28 Certain zoonotic bacterial diseases
0.711 0.289 0.000
A15-A19 Tuberculosis
0.711 0.289 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.710 0.290 0.000
K59.3 Megacolon, not elsewhere classified
0.710 0.290 0.000
A80-A89 Viral infections of the central nervous system
0.709 0.291 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.708 0.292 0.000
K62.2 Anal prolapse
0.708 0.292 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.708 0.292 0.000
J95-J99 Other diseases of the respiratory system
0.707 0.293 0.000
Y83.8 Other surgical procedures
0.707 0.293 0.000
K63.1 Perforation of intestine (nontraumatic)
0.706 0.294 0.000
N88.2 Stricture and stenosis of cervix uteri
0.705 0.295 0.000
J34.2 Deviated nasal septum
0.704 0.296 0.000
F99-F99 Unspecified mental disorder
0.704 0.296 0.000
G90-G99 Other disorders of the nervous system
0.704 0.296 0.000
M47.1 Other spondylosis with myelopathy
0.703 0.296 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.703 0.296 0.000
E78.8 Other disorders of lipoprotein metabolism
0.703 0.296 0.000
E78.6 Lipoprotein deficiency
0.703 0.296 0.000
E78.4 Other hyperlipidaemia
0.703 0.296 0.000
E78.3 Hyperchylomicronaemia
0.703 0.296 0.000
E78.1 Pure hyperglyceridaemia
0.703 0.296 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.703 0.297 0.000
L73 Other follicular disorders
0.703 0.297 0.000
L75 Apocrine sweat disorders
0.702 0.298 0.000
L74 Eccrine sweat disorders
0.702 0.298 0.000
L70 Acne
0.702 0.298 0.000
L68 Hypertrichosis
0.702 0.298 0.000
L67 Hair colour and hair shaft abnormalities
0.702 0.298 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.702 0.298 0.000
L65 Other nonscarring hair loss
0.702 0.298 0.000
L64 Androgenic alopecia
0.702 0.298 0.000
L63 Alopecia areata
0.702 0.298 0.000
L62 Nail disorders in diseases classified elsewhere
0.702 0.298 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.702 0.298 0.000
D45 Polycythaemia vera
0.701 0.299 0.000
M79.0 Rheumatism, unspecified
0.701 0.299 0.000
T87 Complications peculiar to reattachment and amputation
0.700 0.299 0.000
T86 Failure and rejection of transplanted organs and tissues
0.700 0.299 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.700 0.299 0.000
M79.6 Pain in limb
0.700 0.300 0.000
E88 Other metabolic disorders
0.699 0.301 0.000
B18 Chronic viral hepatitis
0.699 0.301 0.000
J32.9 Chronic sinusitis, unspecified
0.698 0.302 0.000
J37 Chronic laryngitis and laryngotracheitis
0.697 0.303 0.000
M45 Ankylosing spondylitis
0.697 0.303 0.000
N76 Other inflammation of vagina and vulva
0.697 0.303 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.697 0.303 0.000
N30 Cystitis
0.697 0.303 0.000
E11.4 With neurological complications
0.696 0.304 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.696 0.304 0.000
K74 Fibrosis and cirrhosis of liver
0.696 0.304 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.696 0.304 0.000
M46 Other inflammatory spondylopathies
0.695 0.304 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.695 0.305 0.000
Z98.1 Arthrodesis status
0.694 0.306 0.000
D80-D89 Certain disorders involving the immune mechanism
0.693 0.307 0.000
T92 Sequelae of injuries of upper limb
0.692 0.307 0.000
S00.0 Superficial injury of scalp
0.692 0.308 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.692 0.308 0.000
E11.2 With renal complications
0.692 0.308 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.691 0.309 0.000
B17 Other acute viral hepatitis
0.690 0.310 0.000
M79.7 Fibromyalgia
0.689 0.311 0.000
L72.2 Steatocystoma multiplex
0.688 0.311 0.000
M77 Other enthesopathies
0.688 0.312 0.000
G20-G26 Extrapyramidal and movement disorders
0.687 0.313 0.000
M71 Other bursopathies
0.687 0.313 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.687 0.313 0.000
M47.86 Other spondylosis (Lumbar region)
0.687 0.313 0.000
L98.0 Pyogenic granuloma
0.686 0.314 0.000
L84 Corns and callosities
0.686 0.314 0.000
B16 Acute hepatitis B
0.685 0.315 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.684 0.315 0.000
F70-F79 Mental retardation
0.684 0.315 0.000
F60-F69 Disorders of adult personality and behaviour
0.684 0.315 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.684 0.315 0.000
Z98.8 Other specified postsurgical states
0.684 0.316 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.683 0.316 0.000
L94 Other localised connective tissue disorders
0.683 0.316 0.000
L93 Lupus erythematosus
0.683 0.316 0.000
L87 Transepidermal elimination disorders
0.683 0.316 0.000
L88 Pyoderma gangrenosum
0.683 0.316 0.000
L86 Keratoderma in diseases classified elsewhere
0.683 0.316 0.000
L83 Acanthosis nigricans
0.683 0.316 0.000
L80 Vitiligo
0.683 0.316 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.683 0.317 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.683 0.317 0.000
H66 Suppurative and unspecified otitis media
0.682 0.318 0.000
K63.3 Ulcer of intestine
0.682 0.318 0.000
E12 Malnutrition-related diabetes mellitus
0.681 0.319 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.681 0.319 0.000
K63.4 Enteroptosis
0.680 0.320 0.000
K63.0 Abscess of intestine
0.680 0.320 0.000
N92.6 Irregular menstruation, unspecified
0.680 0.320 0.000
K59.1 Functional diarrhoea
0.680 0.320 0.000
J33 Nasal polyp
0.680 0.320 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.679 0.321 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.679 0.321 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.679 0.321 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.679 0.321 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.679 0.321 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.679 0.321 0.000
Z88.2 Personal history of allergy to sulphonamides
0.679 0.321 0.000
S50-S59 Injuries to the elbow and forearm
0.678 0.321 0.000
S42 Fracture of shoulder and upper arm
0.678 0.322 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.678 0.322 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.678 0.322 0.000
T91 Sequelae of injuries of neck and trunk
0.678 0.322 0.000
M20-M25 Other joint disorders
0.677 0.323 0.000
N37 Urethral disorders in diseases classified elsewhere
0.677 0.323 0.000
N33 Bladder disorders in diseases classified elsewhere
0.677 0.323 0.000
K60.3 Anal fistula
0.676 0.324 0.000
K61 Abscess of anal and rectal regions
0.676 0.324 0.000
M16 Coxarthrosis [arthrosis of hip]
0.676 0.324 0.000
V10-V19 Pedal cyclist injured in transport accident
0.674 0.325 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.674 0.325 0.000
Y83.3 Surgical operation with formation of external stoma
0.673 0.327 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.673 0.327 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.673 0.327 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.672 0.328 0.000
E11.8 With unspecified complications
0.672 0.328 0.000
E11.7 With multiple complications
0.672 0.328 0.000
E11.1 With ketoacidosis
0.672 0.328 0.000
E11.0 With coma
0.672 0.328 0.000
N39.2 Orthostatic proteinuria, unspecified
0.671 0.329 0.000
N39.1 Persistent proteinuria, unspecified
0.671 0.329 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.670 0.329 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.670 0.330 0.000
N73.6 Female pelvic peritoneal adhesions
0.670 0.330 0.000
E29 Testicular dysfunction
0.670 0.330 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.670 0.330 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.670 0.330 0.000
J90-J94 Other diseases of pleura
0.669 0.331 0.000
L60.0 Ingrowing nail
0.667 0.333 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.666 0.333 0.000
K59.9 Functional intestinal disorder, unspecified
0.665 0.335 0.000
K59.4 Anal spasm
0.665 0.335 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.665 0.335 0.000
M43.1 Spondylolisthesis
0.665 0.335 0.000
T98 Sequelae of other and unspecified effects of external causes
0.665 0.335 0.000
M47.82 Other spondylosis (Cervical region)
0.664 0.336 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.664 0.336 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.664 0.336 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.664 0.336 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.664 0.336 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.664 0.336 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.664 0.336 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.664 0.336 0.000
F11 Mental and behavioural disorders due to use of opioids
0.664 0.336 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.663 0.336 0.000
M48.9 Spondylopathy, unspecified
0.663 0.337 0.000
M48.8 Other specified spondylopathies
0.663 0.337 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.663 0.337 0.000
M48.4 Fatigue fracture of vertebra
0.663 0.337 0.000
M48.3 Traumatic spondylopathy
0.663 0.337 0.000
M48.2 Kissing spine
0.663 0.337 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.663 0.337 0.000
D26 Other benign neoplasms of uterus
0.662 0.337 0.000
D10 Benign neoplasm of mouth and pharynx
0.662 0.338 0.000
S80-S89 Injuries to the knee and lower leg
0.662 0.338 0.000
D27 Benign neoplasm of ovary
0.662 0.338 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.662 0.338 0.000
K75.0 Abscess of liver
0.661 0.339 0.000
H80-H83 Diseases of inner ear
0.661 0.339 0.000
K60.2 Anal fissure, unspecified
0.661 0.339 0.000
K60.0 Acute anal fissure
0.660 0.340 0.000
A48 Other bacterial diseases, not elsewhere classified
0.659 0.341 0.000
A44 Bartonellosis
0.659 0.341 0.000
A43 Nocardiosis
0.659 0.341 0.000
A42 Actinomycosis
0.659 0.341 0.000
A40 Streptococcal septicaemia
0.659 0.341 0.000
A39 Meningococcal infection
0.659 0.341 0.000
A37 Whooping cough
0.659 0.341 0.000
A36 Diphtheria
0.659 0.341 0.000
A32 Listeriosis
0.659 0.341 0.000
A31 Infection due to other mycobacteria
0.659 0.341 0.000
A30 Leprosy [Hansen's disease]
0.659 0.341 0.000
A46 Erysipelas
0.659 0.341 0.000
A38 Scarlet fever
0.659 0.341 0.000
A35 Other tetanus
0.659 0.341 0.000
A34 Obstetrical tetanus
0.659 0.341 0.000
A33 Tetanus neonatorum
0.659 0.341 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.658 0.342 0.000
K91.3 Postoperative intestinal obstruction
0.658 0.342 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.658 0.342 0.000
M05-M14 Inflammatory polyarthropathies
0.657 0.343 0.000
Chapter VII Diseases of the eye and adnexa
0.657 0.343 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.657 0.343 0.000
N94.1 Dyspareunia
0.657 0.343 0.000
D55-D59 Haemolytic anaemias
0.655 0.345 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.655 0.345 0.000
E83.8 Other disorders of mineral metabolism
0.655 0.345 0.000
E83.3 Disorders of phosphorus metabolism
0.655 0.345 0.000
E83.2 Disorders of zinc metabolism
0.655 0.345 0.000
E83.0 Disorders of copper metabolism
0.655 0.345 0.000
D36 Benign neoplasm of other and unspecified sites
0.654 0.346 0.000
W08 Fall involving other furniture
0.654 0.346 0.000
M79.5 Residual foreign body in soft tissue
0.653 0.347 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.652 0.348 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.652 0.348 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.652 0.348 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.652 0.348 0.000
T90 Sequelae of injuries of head
0.652 0.348 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.651 0.349 0.000
N34.2 Other urethritis
0.651 0.349 0.000
M79.8 Other specified soft tissue disorders
0.650 0.350 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.650 0.350 0.000
E28 Ovarian dysfunction
0.650 0.350 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.648 0.352 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.648 0.352 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.648 0.352 0.000
N87 Dysplasia of cervix uteri
0.648 0.352 0.000
K13.0 Diseases of lips
0.648 0.352 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.647 0.353 0.000
B49 Unspecified mycosis
0.647 0.353 0.000
Z34 Supervision of normal pregnancy
0.647 0.353 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.647 0.353 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.647 0.353 0.000
L98.5 Mucinosis of skin
0.647 0.353 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.647 0.353 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.647 0.353 0.000
L98.1 Factitial dermatitis
0.647 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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