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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2425163
log Bayes Factor = 2.5363
Chromosome 20   position 34,432,670  (GRCh37) Explore rs2425163 on Ensembl!
Variant rs2425163 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M17.9 Gonarthrosis, unspecified
0.000 0.007 0.993
M17 Gonarthrosis [arthrosis of knee]
0.000 0.015 0.985
M17.1 Other primary gonarthrosis
0.000 0.021 0.979
M17.0 Primary gonarthrosis, bilateral
0.000 0.150 0.850
M17.5 Other secondary gonarthrosis
0.000 0.196 0.804
M17.3 Other posttraumatic gonarthrosis
0.000 0.286 0.714
M17.4 Other secondary gonarthrosis, bilateral
0.000 0.294 0.706
M17.2 Posttraumatic gonarthrosis, bilateral
0.000 0.294 0.706
M23.3 Other meniscus derangements
0.000 0.454 0.546
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.000 0.464 0.536
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.000 0.473 0.527
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.000 0.486 0.514
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.000 0.502 0.498
M23.30 Other meniscus derangements (Multiple sites)
0.000 0.552 0.448
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.000 0.563 0.437
M23 Internal derangement of knee
0.000 0.581 0.419
M23.2 Derangement of meniscus due to old tear or injury
0.000 0.596 0.404
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.000 0.600 0.400
M23.37 Other meniscus derangements-Capsular lig
0.000 0.608 0.391
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.000 0.643 0.357
M23.4 Loose body in knee
0.000 0.660 0.340
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.000 0.660 0.340
M23.8 Other internal derangements of knee
0.000 0.675 0.325
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.682 0.318
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.693 0.307
M23.9 Internal derangement of knee, unspecified
0.000 0.703 0.297
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.000 0.710 0.290
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.000 0.718 0.282
M23.43 Loose body in knee-Med lig/oth men
0.000 0.721 0.279
M23.1 Discoid meniscus (congenital)
0.000 0.721 0.278
M23.6 Other spontaneous disruption of ligament(s) of knee
0.000 0.726 0.274
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.000 0.733 0.267
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.000 0.733 0.267
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.000 0.746 0.253
M23.49 Loose body in knee-Unspec lig/men
0.000 0.750 0.250
M23.46 Loose body in knee-O/unsp lat men
0.000 0.752 0.248
M23.5 Chronic instability of knee
0.000 0.753 0.247
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.000 0.753 0.246
M23.47 Loose body in knee-Capsular lig
0.000 0.756 0.244
M23.45 Loose body in knee-Pst hrn lat men
0.000 0.756 0.244
M23.44 Loose body in knee-Lat lig/ant men
0.000 0.756 0.244
M23.42 Loose body in knee-Pst lig/hrn men
0.000 0.756 0.244
M23.41 Loose body in knee-Ant lig/hrn men
0.000 0.756 0.244
M23.40 Loose body in knee-Mult sites
0.000 0.756 0.244
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.760 0.240
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.000 0.765 0.235
M23.87 Other internal derangements of knee (Capsular ligament)
0.000 0.767 0.233
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.000 0.767 0.233
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.000 0.767 0.233
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.000 0.767 0.233
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.000 0.768 0.232
M23.80 Other internal derangements of knee (Multiple sites)
0.000 0.779 0.221
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.000 0.781 0.219
M23.97 Internal derangement of knee, unspecified (Capsular ligament)
0.000 0.787 0.213
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)
0.000 0.787 0.213
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)
0.000 0.787 0.213
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.000 0.787 0.213
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.000 0.787 0.213
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.787 0.213
M23.90 Internal derangement of knee, unspecified (Multiple sites)
0.000 0.787 0.213
M23.0 Cystic meniscus
0.000 0.787 0.212
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.000 0.790 0.210
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)
0.000 0.800 0.200
M23.17 Discoid meniscus (congenital)-Capsular lig
0.000 0.800 0.200
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)
0.000 0.800 0.200
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.000 0.800 0.200
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)
0.000 0.800 0.200
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.000 0.800 0.200
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.800 0.200
M23.10 Discoid meniscus (congenital) (Multiple sites)
0.000 0.800 0.200
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)
0.000 0.804 0.196
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)
0.000 0.804 0.196
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp
0.000 0.804 0.196
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn
0.000 0.804 0.196
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.000 0.804 0.196
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.000 0.804 0.196
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.000 0.804 0.196
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)
0.000 0.804 0.196
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)
0.000 0.816 0.183
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)
0.000 0.822 0.178
M23.57 Chronic instability of knee (Capsular ligament)
0.000 0.822 0.177
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)
0.000 0.822 0.177
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)
0.000 0.822 0.177
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.000 0.822 0.177
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.000 0.822 0.177
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.000 0.822 0.177
M23.50 Chronic instability of knee (Multiple sites)
0.000 0.822 0.177
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.830 0.169
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)
0.000 0.838 0.162
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)
0.000 0.845 0.155
M23.07 Cystic meniscus-Capsular lig
0.000 0.847 0.152
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)
0.000 0.847 0.152
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.000 0.847 0.152
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.000 0.847 0.152
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.847 0.152
M23.00 Cystic meniscus (Multiple sites)
0.000 0.847 0.152
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.000 0.853 0.147
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)
0.000 0.871 0.129
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)
0.001 0.898 0.101
M20.1 Hallux valgus (acquired)
0.000 0.919 0.081
M20 Acquired deformities of fingers and toes
0.000 0.942 0.058
M20-M25 Other joint disorders
0.000 0.943 0.057
M20.5 Other deformities of toe(s) (acquired)
0.000 0.944 0.056
M21 Other acquired deformities of limbs
0.000 0.951 0.049
M15-M19 Arthrosis
0.000 0.952 0.048
M21.1 Varus deformity, not elsewhere classified
0.000 0.954 0.046
M34 Systemic sclerosis
0.000 0.957 0.043
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.000 0.957 0.043
M32 Systemic lupus erythematosus
0.000 0.958 0.041
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.959 0.041
M21.6 Other acquired deformities of ankle and foot
0.000 0.959 0.041
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.959 0.041
M21.4 Flat foot [pes planus] (acquired)
0.000 0.961 0.039
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.000 0.963 0.037
M21.9 Acquired deformity of limb, unspecified
0.000 0.965 0.035
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.000 0.965 0.035
M21.3 Wrist or foot drop (acquired)
0.000 0.965 0.035
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.000 0.965 0.035
M34.8 Other forms of systemic sclerosis
0.000 0.966 0.034
Y43.3 Other antineoplastic drugs
0.034 0.966 0.000
M34.9 Systemic sclerosis, unspecified
0.000 0.966 0.034
M21.2 Flexion deformity
0.000 0.966 0.034
M30 Polyarteritis nodosa and related conditions
0.000 0.966 0.033
M33 Dermatopolymyositis
0.000 0.966 0.033
M21.19 Varus deformity, not elsewhere classified (Site unspecified)
0.000 0.967 0.033
M21.18 Varus deformity, not elsewhere classified (Other)
0.000 0.967 0.033
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)
0.000 0.967 0.033
M21.14 Varus deformity, not elsewhere classified (Hand)
0.000 0.967 0.033
M21.13 Varus deformity, not elsewhere classified (Forearm)
0.000 0.967 0.033
M21.12 Varus deformity, not elsewhere classified (Upper arm)
0.000 0.967 0.033
M21.11 Varus deformity, not elsewhere classified (Shoulder region)
0.000 0.967 0.033
M21.10 Varus deformity, not elsewhere classified (Multiple sites)
0.000 0.967 0.033
M21.8 Other specified acquired deformities of limbs
0.000 0.967 0.033
N93.8 Other specified abnormal uterine and vaginal bleeding
0.000 0.967 0.033
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.000 0.969 0.031
M34.2 Systemic sclerosis induced by drugs and chemicals
0.000 0.969 0.031
M34.0 Progressive systemic sclerosis
0.000 0.969 0.031
M18 Arthrosis of first carpometacarpal joint
0.000 0.969 0.031
M32.1 Systemic lupus erythematosus with organ or system involvement
0.000 0.969 0.031
M32.9 Systemic lupus erythematosus, unspecified
0.000 0.970 0.030
M32.8 Other forms of systemic lupus erythematosus
0.000 0.970 0.030
M32.0 Drug-induced systemic lupus erythematosus
0.000 0.970 0.030
Y43 Primarily systemic agents
0.030 0.970 0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec
0.000 0.970 0.029
M21.68 Other acquired deformities of ankle and foot-Other
0.000 0.970 0.029
M21.66 Other acquired deformities of ankle and foot-Lower leg
0.000 0.970 0.029
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh
0.000 0.970 0.029
M21.64 Other acquired deformities of ankle and foot-Hand
0.000 0.970 0.029
M21.63 Other acquired deformities of ankle and foot-Forearm
0.000 0.970 0.029
M21.62 Other acquired deformities of ankle and foot-Upper arm
0.000 0.970 0.029
M21.61 Other acquired deformities of ankle and foot-Shldr region
0.000 0.970 0.029
M21.60 Other acquired deformities of ankle and foot-Mult sites
0.000 0.970 0.029
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.000 0.970 0.029
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.000 0.970 0.029
M36.3 Arthropathy in other blood disorders
0.000 0.970 0.029
M36.2 Haemophilic arthropathy
0.000 0.970 0.029
M36.1 Arthropathy in neoplastic disease
0.000 0.970 0.029
M36.0 Dermato(poly)myositis in neoplastic disease
0.000 0.970 0.029
M15 Polyarthrosis
0.000 0.970 0.029
M21.7 Unequal limb length (acquired)
0.000 0.972 0.028
M31 Other necrotising vasculopathies
0.000 0.972 0.028
M21.27 Flexion deformity (Ankle and foot)
0.000 0.972 0.028
M21.49 Flat foot [pes planus] (acquired)-Site unspec
0.000 0.972 0.028
M21.48 Flat foot [pes planus] (acquired)-Other
0.000 0.972 0.028
M21.46 Flat foot [pes planus] (acquired)-Lower leg
0.000 0.972 0.028
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh
0.000 0.972 0.028
M21.44 Flat foot [pes planus] (acquired)-Hand
0.000 0.972 0.028
M21.43 Flat foot [pes planus] (acquired)-Forearm
0.000 0.972 0.028
M21.42 Flat foot [pes planus] (acquired)-Upper arm
0.000 0.972 0.028
M21.41 Flat foot [pes planus] (acquired)-Shldr region
0.000 0.972 0.028
M21.40 Flat foot [pes planus] (acquired)-Mult sites
0.000 0.972 0.028
M34.1 CR(E)ST syndrome
0.000 0.972 0.027
M20.0 Deformity of finger(s)
0.000 0.973 0.027
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.000 0.974 0.026
M31.3 Wegener's granulomatosis
0.000 0.974 0.026
Y43.4 Immunosuppressive agents
0.026 0.974 0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)
0.000 0.974 0.025
M21.98 Acquired deformity of limb, unspecified-Other
0.000 0.974 0.025
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)
0.000 0.974 0.025
M21.96 Acquired deformity of limb, unspecified (Lower leg)
0.000 0.974 0.025
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)
0.000 0.974 0.025
M21.94 Acquired deformity of limb, unspecified (Hand)
0.000 0.974 0.025
M21.93 Acquired deformity of limb, unspecified (Forearm)
0.000 0.974 0.025
M21.92 Acquired deformity of limb, unspecified (Upper arm)
0.000 0.974 0.025
M21.91 Acquired deformity of limb, unspecified (Shoulder region)
0.000 0.974 0.025
M21.90 Acquired deformity of limb, unspecified (Multiple sites)
0.000 0.974 0.025
M30.0 Polyarteritis nodosa
0.000 0.974 0.025
M20.4 Other hammer toe(s) (acquired)
0.000 0.975 0.025
M21.39 Wrist or foot drop (acquired)-Site unspec
0.000 0.975 0.025
M21.38 Wrist or foot drop (acquired)-Other
0.000 0.975 0.025
M21.36 Wrist or foot drop (acquired)-Lower leg
0.000 0.975 0.025
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh
0.000 0.975 0.025
M21.34 Wrist or foot drop (acquired) (Hand)
0.000 0.975 0.025
M21.33 Wrist or foot drop (acquired) (Forearm)
0.000 0.975 0.025
M21.32 Wrist or foot drop (acquired)-Upper arm
0.000 0.975 0.025
M21.31 Wrist or foot drop (acquired)-Shldr region
0.000 0.975 0.025
M21.30 Wrist or foot drop (acquired) (Multiple sites)
0.000 0.975 0.025
M21.0 Valgus deformity, not elsewhere classified
0.000 0.975 0.025
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns
0.000 0.975 0.025
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other
0.000 0.975 0.025
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le
0.000 0.975 0.025
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t
0.000 0.975 0.025
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)
0.000 0.975 0.025
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm
0.000 0.975 0.025
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar
0.000 0.975 0.025
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re
0.000 0.975 0.025
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)
0.000 0.975 0.025
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.000 0.975 0.025
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.000 0.975 0.024
M21.29 Flexion deformity (Site unspecified)
0.000 0.975 0.024
M21.28 Flexion deformity (Other)
0.000 0.975 0.024
M21.25 Flexion deformity (Pelvic region and thigh)
0.000 0.975 0.024
M21.23 Flexion deformity (Forearm)
0.000 0.975 0.024
M21.22 Flexion deformity (Upper arm)
0.000 0.975 0.024
M21.21 Flexion deformity (Shoulder region)
0.000 0.975 0.024
M21.20 Flexion deformity (Multiple sites)
0.000 0.975 0.024
M30.8 Other conditions related to polyarteritis nodosa
0.000 0.976 0.024
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.000 0.976 0.024
M30.2 Juvenile polyarteritis
0.000 0.976 0.024
M33.9 Dermatopolymyositis, unspecified
0.000 0.976 0.024
M33.0 Juvenile dermatomyositis
0.000 0.976 0.024
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.024 0.976 0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)
0.000 0.976 0.024
M21.88 Other specified acquired deformities of limbs-Other
0.000 0.976 0.024
M21.87 Other specified acquired deformities of limbs (Ankle and foot)
0.000 0.976 0.024
M21.86 Other specified acquired deformities of limbs (Lower leg)
0.000 0.976 0.024
M21.84 Other specified acquired deformities of limbs (Hand)
0.000 0.976 0.024
M21.83 Other specified acquired deformities of limbs (Forearm)
0.000 0.976 0.024
M21.82 Other specified acquired deformities of limbs (Upper arm)
0.000 0.976 0.024
M21.81 Other specified acquired deformities of limbs (Shoulder region)
0.000 0.976 0.024
M21.80 Other specified acquired deformities of limbs (Multiple sites)
0.000 0.976 0.024
K90.0 Coeliac disease
0.024 0.976 0.000
Y43.0 Antiallergic and antiemetic drugs
0.023 0.977 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.023 0.977 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.000 0.977 0.023
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.000 0.977 0.023
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.000 0.977 0.023
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.000 0.977 0.023
M33.1 Other dermatomyositis
0.000 0.978 0.022
M20.3 Other deformity of hallux (acquired)
0.000 0.978 0.022
M21.26 Flexion deformity (Lower leg)
0.000 0.978 0.022
Z96.0 Presence of urogenital implants
0.000 0.978 0.022
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)
0.000 0.978 0.022
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites
0.000 0.978 0.022
Y43.9 Primarily systemic agent, unspecified
0.022 0.978 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.022 0.978 0.000
Y43.6 Enzymes, not elsewhere classified
0.022 0.978 0.000
Y43.5 Acidifying and alkalising agents
0.022 0.978 0.000
Y43.2 Antineoplastic natural products
0.022 0.978 0.000
M15.0 Primary generalised (osteo)arthrosis
0.000 0.979 0.021
M15.8 Other polyarthrosis
0.000 0.979 0.021
M15.4 Erosive (osteo)arthrosis
0.000 0.979 0.021
M15.3 Secondary multiple arthrosis
0.000 0.979 0.021
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.021 0.979 0.000
M15.9 Polyarthrosis, unspecified
0.000 0.979 0.021
M21.79 Unequal limb length (acquired) (Site unspecified)
0.000 0.979 0.020
M21.78 Unequal limb length (acquired)-Other
0.000 0.979 0.020
M21.77 Unequal limb length (acquired) (Ankle and foot)
0.000 0.979 0.020
M21.76 Unequal limb length (acquired) (Lower leg)
0.000 0.979 0.020
M21.74 Unequal limb length (acquired) (Hand)
0.000 0.979 0.020
M21.73 Unequal limb length (acquired) (Forearm)
0.000 0.979 0.020
M21.72 Unequal limb length (acquired) (Upper arm)
0.000 0.979 0.020
M21.71 Unequal limb length (acquired)-Shldr region
0.000 0.979 0.020
M21.70 Unequal limb length (acquired) (Multiple sites)
0.000 0.979 0.020
M31.9 Necrotising vasculopathy, unspecified
0.000 0.979 0.020
M31.8 Other specified necrotising vasculopathies
0.000 0.979 0.020
M31.7 Microscopic polyangiitis
0.000 0.979 0.020
M31.4 Aortic arch syndrome [Takayasu]
0.000 0.979 0.020
M31.2 Lethal midline granuloma
0.000 0.979 0.020
M33.2 Polymyositis
0.000 0.980 0.020
Y44 Agents primarily affecting blood constituents
0.020 0.980 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.020 0.980 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.000 0.980 0.020
M15.1 Heberden's nodes (with arthropathy)
0.000 0.980 0.020
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.020 0.980 0.000
M21.24 Flexion deformity (Hand)
0.000 0.981 0.019
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.019 0.981 0.000
Y43.1 Antineoplastic antimetabolites
0.019 0.981 0.000
M15.2 Bouchard's nodes (with arthropathy)
0.000 0.981 0.019
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.019 0.981 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.019 0.981 0.000
M31.1 Thrombotic microangiopathy
0.000 0.981 0.019
Y59 Other and unspecified vaccines and biological substances
0.019 0.981 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.019 0.981 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.018 0.981 0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)
0.000 0.982 0.018
M21.08 Valgus deformity, not elsewhere classified (Other)
0.000 0.982 0.018
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)
0.000 0.982 0.018
M21.04 Valgus deformity, not elsewhere classified (Hand)
0.000 0.982 0.018
M21.03 Valgus deformity, not elsewhere classified (Forearm)
0.000 0.982 0.018
M21.02 Valgus deformity, not elsewhere classified (Upper arm)
0.000 0.982 0.018
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)
0.000 0.982 0.018
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)
0.000 0.982 0.018
M31.0 Hypersensitivity angiitis
0.000 0.982 0.018
Y52 Agents primarily affecting the cardiovascular system
0.018 0.982 0.000
B07 Viral warts
0.000 0.982 0.018
Y58 Bacterial vaccines
0.018 0.982 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.018 0.982 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.018 0.982 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.000 0.983 0.017
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.017 0.983 0.000
M35 Other systemic involvement of connective tissue
0.000 0.983 0.017
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.017 0.983 0.000
M22 Disorders of patella
0.000 0.983 0.016
Y46.2 Hydantoin derivatives
0.017 0.983 0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.016 0.983 0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.016 0.983 0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.016 0.983 0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.016 0.983 0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.016 0.983 0.000
Y51.1 Other parasympathomimetics [cholinergics]
0.016 0.983 0.000
Y51.0 Anticholinesterase agents
0.016 0.983 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.016 0.983 0.000
Y54.3 Benzothiadiazine derivatives
0.016 0.984 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.016 0.984 0.000
Y44.2 Anticoagulants
0.016 0.984 0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants
0.016 0.984 0.000
Y41.1 Antimycobacterial drugs
0.016 0.984 0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites
0.000 0.984 0.015
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.000 0.984 0.015
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.015 0.984 0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system
0.015 0.985 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.001 0.985 0.015
Y44.5 Thrombolytic drugs
0.015 0.985 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.015 0.985 0.000
Y59.3 Immunoglobulin
0.015 0.985 0.000
Y47.1 Benzodiazepines
0.015 0.985 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.015 0.985 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.015 0.985 0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified
0.014 0.985 0.000
Y41.4 Anthelminthics
0.014 0.985 0.000
Y41.3 Other antiprotozoal drugs
0.014 0.985 0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa
0.014 0.985 0.000
Y44.9 Other and unspecified agents affecting blood constituents
0.014 0.985 0.000
Y44.7 Plasma substitutes
0.014 0.985 0.000
Y44.6 Natural blood and blood products
0.014 0.985 0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.014 0.985 0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations
0.014 0.985 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.015 0.985 0.000
M15.99 Polyosteoarthritis, unspecified
0.000 0.985 0.014
Y57 Other and unspecified drugs and medicaments
0.015 0.985 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.014 0.985 0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations
0.014 0.986 0.000
Y54.5 Other diuretics
0.014 0.986 0.000
Y56.9 Topical agent, unspecified
0.014 0.986 0.000
Y56.8 Other topical agents
0.014 0.986 0.000
Y56.7 Dental drugs, topically applied
0.014 0.986 0.000
Y56.6 Otorhinolaryngological drugs and preparations
0.014 0.986 0.000
Y56.5 Ophthalmological drugs and preparations
0.014 0.986 0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.014 0.986 0.000
Y56.3 Emollients, demulcents and protectants
0.014 0.986 0.000
Y56.2 Local astringents and local detergents
0.014 0.986 0.000
Y56.1 Antipruritics
0.014 0.986 0.000
Y41.0 Sulphonamides
0.014 0.986 0.000
K81.9 Cholecystitis, unspecified
0.014 0.986 0.000
Y48 Anaesthetics and therapeutic gases
0.014 0.986 0.000
Y41.5 Antiviral drugs
0.014 0.986 0.000
Y54.9 Mineral salts, not elsewhere classified
0.014 0.986 0.000
Y54.7 Agents affecting calcification
0.014 0.986 0.000
Y54.6 Electrolytic, caloric and water-balance agents
0.014 0.986 0.000
Y54.2 Carbonic-anhydrase inhibitors
0.014 0.986 0.000
Y54.0 Mineralocorticoids
0.014 0.986 0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.014 0.986 0.000
Y53.7 Emetics
0.014 0.986 0.000
Y53.6 Antidiarrhoeal drugs
0.014 0.986 0.000
Y53.5 Digestants
0.014 0.986 0.000
Y53.3 Saline and osmotic laxatives
0.014 0.986 0.000
Y53.2 Stimulant laxatives
0.014 0.986 0.000
Y53.0 Histamine H2-receptor antagonists
0.014 0.986 0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)
0.001 0.986 0.013
Y59.9 Vaccine or biological substance, unspecified
0.014 0.986 0.000
Y59.8 Other specified vaccines and biological substances
0.014 0.986 0.000
Y59.2 Protozoal vaccines
0.014 0.986 0.000
Y59.1 Rickettsial vaccines
0.014 0.986 0.000
Y59.0 Viral vaccines
0.014 0.986 0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified
0.014 0.986 0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs
0.014 0.986 0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified
0.014 0.986 0.000
Y47.4 Bromine compounds
0.014 0.986 0.000
Y47.3 Paraldehyde
0.014 0.986 0.000
Y47.2 Chloral derivatives
0.014 0.986 0.000
Y47.0 Barbiturates, not elsewhere classified
0.014 0.986 0.000
Y52.1 Calcium-channel blockers
0.013 0.986 0.000
M22.2 Patellofemoral disorders
0.000 0.986 0.013
Y46.8 Antispasticity drugs
0.013 0.986 0.000
Y46.7 Anti-Parkinsonism drugs
0.013 0.986 0.000
Y46.5 Valproic acid
0.013 0.986 0.000
Y46.3 Deoxybarbiturates
0.013 0.986 0.000
Y46.1 Oxazolidinediones
0.013 0.986 0.000
Y46.0 Succinimides
0.013 0.986 0.000
M35.7 Hypermobility syndrome
0.000 0.986 0.013
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.001 0.987 0.013
M35.1 Other overlap syndromes
0.000 0.987 0.013
Y40 Systemic antibiotics
0.013 0.987 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.013 0.987 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.013 0.987 0.000
Y52.7 Peripheral vasodilators
0.013 0.987 0.000
Y54.4 Loop [high-ceiling] diuretics
0.013 0.987 0.000
Y53.4 Other laxatives
0.013 0.987 0.000
Y50.9 Central nervous system stimulant, unspecified
0.013 0.987 0.000
Y50.8 Other central nervous system stimulants
0.013 0.987 0.000
Y50.2 Methylxanthines, not elsewhere classified
0.013 0.987 0.000
Y50.1 Opioid receptor antagonists
0.013 0.987 0.000
Y50.0 Analeptics
0.013 0.987 0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system
0.013 0.987 0.000
Y55.6 Antiasthmatics, not elsewhere classified
0.013 0.987 0.000
Y55.5 Anticommon cold drugs
0.013 0.987 0.000
Y55.4 Expectorants
0.013 0.987 0.000
Y55.3 Antitussives
0.013 0.987 0.000
Y55.2 Other and unspecified agents primarily acting on muscles
0.013 0.987 0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.013 0.987 0.000
Y55.0 Oxytocic drugs
0.013 0.987 0.000
Y58.9 Other and unspecified bacterial vaccines
0.013 0.987 0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component
0.013 0.987 0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component
0.013 0.987 0.000
Y58.5 Diphtheria vaccine
0.013 0.987 0.000
Y58.4 Tetanus vaccine
0.013 0.987 0.000
Y58.3 Plague vaccine
0.013 0.987 0.000
Y58.2 Cholera vaccine
0.013 0.987 0.000
Y58.1 Typhoid and paratyphoid vaccine
0.013 0.987 0.000
Y58.0 BCG vaccine
0.013 0.987 0.000
Y45.5 4-Aminophenol derivatives
0.013 0.987 0.000
Y46.6 Other and unspecified antiepileptics
0.012 0.987 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.987 0.012
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.987 0.012
M35.5 Multifocal fibrosclerosis
0.000 0.987 0.012
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.987 0.012
M22.0 Recurrent dislocation of patella
0.000 0.988 0.012
N93 Other abnormal uterine and vaginal bleeding
0.000 0.988 0.012
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.012 0.988 0.000
M22.1 Recurrent subluxation of patella
0.000 0.988 0.012
M22.9 Disorder of patella, unspecified
0.000 0.988 0.012
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.012 0.988 0.000
Y54.8 Agents affecting uric acid metabolism
0.012 0.988 0.000
M35.2 Behcet's disease
0.000 0.988 0.012
M35.8 Other specified systemic involvement of connective tissue
0.000 0.988 0.012
Y52.3 Coronary vasodilators, not elsewhere classified
0.011 0.988 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.011 0.988 0.000
S52.10 Fracture of upper end of radius (closed)
0.000 0.989 0.011
Y42.1 Thyroid hormones and substitutes
0.011 0.989 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.011 0.989 0.000
Y40.6 Rifamycins
0.011 0.989 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.001 0.989 0.010
Y57.8 Other drugs and medicaments
0.011 0.989 0.000
Y42.9 Other and unspecified hormone antagonists
0.011 0.989 0.000
Y42.4 Oral contraceptives
0.011 0.989 0.000
Y42.2 Antithyroid drugs
0.011 0.989 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.011 0.989 0.000
Y45.4 Antirheumatics
0.011 0.989 0.000
Y57.7 Vitamins, not elsewhere classified
0.011 0.989 0.000
Y57.4 Pharmaceutical excipients
0.011 0.989 0.000
Y57.3 Alcohol deterrents
0.011 0.989 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.011 0.989 0.000
Y57.1 Lipotropic drugs
0.011 0.989 0.000
Y57.0 Appetite depressants [anorectics]
0.011 0.989 0.000
Y49.9 Psychotropic drug, unspecified
0.010 0.989 0.000
Y49.8 Other psychotropic drugs, not elsewhere classified
0.010 0.989 0.000
Y49.7 Psychostimulants with abuse potential
0.010 0.989 0.000
Y49.6 Psychodysleptics [hallucinogens]
0.010 0.989 0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics
0.010 0.989 0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics
0.010 0.989 0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants
0.010 0.989 0.000
X62.9 Unspecified place
0.011 0.989 0.000
Y57.5 X-ray contrast media
0.010 0.989 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.010 0.989 0.000
Y45.1 Salicylates
0.011 0.989 0.000
M22.3 Other derangements of patella
0.000 0.989 0.010
Y48.5 Therapeutic gases
0.010 0.989 0.000
Y48.1 Parenteral anaesthetics
0.010 0.989 0.000
Y48.0 Inhaled anaesthetics
0.010 0.989 0.000
Y40.9 Systemic antibiotic, unspecified
0.010 0.990 0.000
Y49.0 Tricyclic and tetracyclic antidepressants
0.010 0.990 0.000
Y40.3 Macrolides
0.010 0.990 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.010 0.990 0.000
Y46.4 Iminostilbenes
0.010 0.990 0.000
Y42.7 Androgens and anabolic congeners
0.010 0.990 0.000
Y49.2 Other and unspecified antidepressants
0.010 0.990 0.000
X60-X84 Intentional self-harm
0.010 0.990 0.000
Y57.6 Other diagnostic agents
0.010 0.990 0.000
Y48.3 Local anaesthetics
0.010 0.990 0.000
Chapter XX External causes of morbidity and mortality
0.010 0.990 0.000
Y40.7 Antifungal antibiotics, systemically used
0.010 0.990 0.000
Y40.5 Aminoglycosides
0.010 0.990 0.000
Y40.4 Tetracyclines
0.010 0.990 0.000
Y40.2 Chloramphenicol group
0.010 0.990 0.000
M24 Other specific joint derangements
0.001 0.990 0.009
Y48.2 Other and unspecified general anaesthetics
0.009 0.990 0.000
Y45.8 Other analgesics and antipyretics
0.009 0.991 0.000
Y48.4 Anaesthetic, unspecified
0.009 0.991 0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.991 0.009
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.009 0.991 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.000 0.991 0.009
Y49.5 Other antipsychotics and neuroleptics
0.009 0.991 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.009 0.991 0.000
M22.10 Recurrent subluxation of patella, unspecified knee
0.000 0.991 0.009
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.009 0.991 0.000
Y40.8 Other systemic antibiotics
0.009 0.991 0.000
R59.0 Localised enlarged lymph nodes
0.009 0.991 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.009 0.991 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.000 0.991 0.009

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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