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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2428475
log Bayes Factor = 82.1548
Chromosome 6   position 31,366,622  (GRCh37) Explore rs2428475 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
M07.30 Other psoriatic arthropathies (Multiple sites)
0.999 0.001 0.000
M07.3 Other psoriatic arthropathies
0.998 0.002 0.000
M45 Ankylosing spondylitis
0.998 0.002 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.998 0.002 0.000
E03 Other hypothyroidism
0.000 0.003 0.997
E27 Other disorders of adrenal gland
0.000 0.003 0.997
E27.1 Primary adrenocortical insufficiency
0.000 0.003 0.997
E03.9 Hypothyroidism, unspecified
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.004 0.996
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.004 0.996
E20-E35 Disorders of other endocrine glands
0.000 0.004 0.996
M07.39 Other psoriatic arthropathies (Site unspecified)
0.995 0.005 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.007 0.993
L40.0 Psoriasis vulgaris
0.992 0.008 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.010 0.990
E16.2 Hypoglycaemia, unspecified
0.000 0.011 0.989
E10.1 With ketoacidosis
0.000 0.016 0.984
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.042 0.958
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.046 0.954
E05.9 Thyrotoxicosis, unspecified
0.000 0.052 0.948
E10.4 With neurological complications
0.000 0.063 0.937
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.929 0.071 0.000
E10.0 With coma
0.000 0.080 0.920
E14 Unspecified diabetes mellitus
0.000 0.097 0.903
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.106 0.894
E27.2 Addisonian crisis
0.000 0.127 0.873
E20 Hypoparathyroidism
0.000 0.136 0.864
M07.34 Other psoriatic arthropathies (Hand)
0.859 0.141 0.000
K90 Intestinal malabsorption
0.000 0.149 0.851
L40.4 Guttate psoriasis
0.846 0.153 0.000
E14.9 Without complications
0.000 0.161 0.839
E10.2 With renal complications
0.000 0.176 0.824
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.808 0.192 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.200 0.800
M07.38 Other psoriatic arthropathies (Other)
0.791 0.209 0.000
L40.1 Generalised pustular psoriasis
0.777 0.223 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.774 0.226 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.230 0.770
M45.X6 Ankylosing spondylitis (Lumbar region)
0.767 0.233 0.000
L40-L45 Papulosquamous disorders
0.762 0.238 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.239 0.761
M45.X2 Ankylosing spondylitis (Cervical region)
0.759 0.241 0.000
E10.5 With peripheral circulatory complications
0.000 0.251 0.749
M07.31 Other psoriatic arthropathies (Shoulder region)
0.747 0.253 0.000
L40.8 Other psoriasis
0.738 0.262 0.000
K90.8 Other intestinal malabsorption
0.000 0.271 0.729
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.272 0.728
E10.7 With multiple complications
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.716
M07.33 Other psoriatic arthropathies (Forearm)
0.716 0.284 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.716 0.284 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.716 0.284 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.716 0.284 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.716 0.284 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.716 0.284 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.716 0.284 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.716 0.284 0.000
E03.5 Myxoedema coma
0.000 0.285 0.715
E03.4 Atrophy of thyroid (acquired)
0.000 0.285 0.715
E03.3 Postinfectious hypothyroidism
0.000 0.285 0.715
E27.5 Adrenomedullary hyperfunction
0.000 0.285 0.715
E27.0 Other adrenocortical overactivity
0.000 0.285 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.286 0.714
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.286 0.714
E32 Diseases of thymus
0.000 0.286 0.714
E31 Polyglandular dysfunction
0.000 0.286 0.714
E30 Disorders of puberty, not elsewhere classified
0.000 0.286 0.714
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.288 0.712
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.288 0.712
E16.4 Abnormal secretion of gastrin
0.000 0.288 0.712
E16.3 Increased secretion of glucagon
0.000 0.288 0.712
E05.5 Thyroid crisis or storm
0.000 0.290 0.710
E05.4 Thyrotoxicosis factitia
0.000 0.290 0.710
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.290 0.710
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.290 0.710
E10.6 With other specified complications
0.000 0.291 0.709
E03.1 Congenital hypothyroidism without goitre
0.000 0.297 0.703
L42 Pityriasis rosea
0.701 0.299 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.302 0.698
E14.6 With other specified complications
0.000 0.302 0.698
E27.8 Other specified disorders of adrenal gland
0.000 0.305 0.695
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.307 0.693
E25 Adrenogenital disorders
0.000 0.312 0.688
E40-E46 Malnutrition
0.000 0.312 0.688
L40.3 Pustulosis palmaris et plantaris
0.684 0.316 0.000
E14.1 With ketoacidosis
0.000 0.322 0.678
E07 Other disorders of thyroid
0.000 0.323 0.677
E10.8 With unspecified complications
0.000 0.331 0.669
E23 Hypofunction and other disorders of pituitary gland
0.000 0.337 0.663
E14.5 With peripheral circulatory complications
0.000 0.341 0.659
E34 Other endocrine disorders
0.000 0.342 0.658
E14.2 Withrenal complications
0.000 0.346 0.654
E14.7 With multiple complications
0.000 0.353 0.647
E14.0 With coma
0.000 0.353 0.647
E26 Hyperaldosteronism
0.000 0.354 0.645
E22 Hyperfunction of pituitary gland
0.000 0.364 0.636
E03.8 Other specified hypothyroidism
0.000 0.365 0.635
E20.8 Other hypoparathyroidism
0.000 0.380 0.620
E20.1 Pseudohypoparathyroidism
0.000 0.380 0.620
E20.0 Idiopathic hypoparathyroidism
0.000 0.380 0.620
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.380 0.620
E14.8 With unspecified complications
0.000 0.381 0.618
E05.8 Other thyrotoxicosis
0.000 0.382 0.618
E28 Ovarian dysfunction
0.000 0.385 0.615
K90.3 Pancreatic steatorrhoea
0.000 0.390 0.610
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.390 0.610
K90.1 Tropical sprue
0.000 0.390 0.610
E13 Other specified diabetes mellitus
0.000 0.393 0.607
L41 Parapsoriasis
0.601 0.398 0.000
E14.3 With ophthalmic complications
0.000 0.404 0.596
E14.4 With neurological complications
0.000 0.414 0.586
E23.2 Diabetes insipidus
0.000 0.421 0.579
E07.8 Other specified disorders of thyroid
0.000 0.422 0.577
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.452 0.548
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.547 0.453 0.000
L44 Other papulosquamous disorders
0.546 0.453 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.546 0.453 0.000
E06 Thyroiditis
0.000 0.455 0.544
L43 Lichen planus
0.534 0.466 0.000
E29 Testicular dysfunction
0.000 0.470 0.530
E34.9 Endocrine disorder, unspecified
0.000 0.475 0.525
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.520 0.480 0.000
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.488 0.512
E30.8 Other disorders of puberty
0.000 0.488 0.512
E30.1 Precocious puberty
0.000 0.488 0.512
E30.0 Delayed puberty
0.000 0.488 0.512
E31.9 Polyglandular dysfunction, unspecified
0.000 0.488 0.512
E31.8 Other polyglandular dysfunction
0.000 0.488 0.512
E31.1 Polyglandular hyperfunction
0.000 0.488 0.512
E31.0 Autoimmune polyglandular failure
0.000 0.488 0.512
E32.9 Disease of thymus, unspecified
0.000 0.488 0.512
E32.8 Other diseases of thymus
0.000 0.488 0.512
E32.1 Abscess of thymus
0.000 0.488 0.512
E32.0 Persistent hyperplasia of thymus
0.000 0.488 0.512
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.488 0.512
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.488 0.512
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.488 0.512
E28.3 Primary ovarian failure
0.000 0.493 0.507
E23.7 Disorder of pituitary gland, unspecified
0.000 0.494 0.506
E34.8 Other specified endocrine disorders
0.000 0.495 0.505
E65-E68 Obesity and other hyperalimentation
0.000 0.502 0.498
E27.9 Disorder of adrenal gland, unspecified
0.000 0.502 0.497
E16.1 Other hypoglycaemia
0.001 0.505 0.495
E25.9 Adrenogenital disorder, unspecified
0.000 0.506 0.493
E25.8 Other adrenogenital disorders
0.000 0.506 0.493
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.507 0.493
E45 Retarded development following protein-energy malnutrition
0.000 0.507 0.493
E43 Unspecified severe protein-energy malnutrition
0.000 0.507 0.493
E42 Marasmic kwashiorkor
0.000 0.507 0.493
E41 Nutritional marasmus
0.000 0.507 0.493
E40 Kwashiorkor
0.000 0.507 0.493
E22.1 Hyperprolactinaemia
0.000 0.509 0.491
L41.1 Pityriasis lichenoides chronica
0.486 0.514 0.000
E07.1 Dyshormogenetic goitre
0.000 0.514 0.486
E07.0 Hypersecretion of calcitonin
0.000 0.514 0.486
C82.0 Small cleaved cell, follicular
0.478 0.522 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.525 0.475
E23.1 Drug-induced hypopituitarism
0.000 0.525 0.475
E34.5 Androgen resistance syndrome
0.000 0.528 0.472
E34.4 Constitutional tall stature
0.000 0.528 0.472
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.528 0.472
E34.1 Other hypersecretion of intestinal hormones
0.000 0.528 0.472
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.532 0.468
E50-E64 Other nutritional deficiencies
0.000 0.533 0.467
E46 Unspecified protein-energy malnutrition
0.000 0.536 0.464
E26.8 Other hyperaldosteronism
0.000 0.537 0.463
E26.1 Secondary hyperaldosteronism
0.000 0.537 0.463
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.544 0.456
E22.8 Other hyperfunction of pituitary gland
0.000 0.544 0.456
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.454 0.546 0.000
M07 Psoriatic and enteropathic arthropathies
0.446 0.554 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.555 0.444
E28.9 Ovarian dysfunction, unspecified
0.000 0.559 0.441
E28.8 Other ovarian dysfunction
0.000 0.559 0.441
E28.1 Androgen excess
0.000 0.559 0.441
E28.0 Oestrogen excess
0.000 0.559 0.441
E13.8 With unspecified complications
0.000 0.564 0.435
E13.7 With multiple complications
0.000 0.564 0.435
E13.6 With other specified complications
0.000 0.564 0.435
E13.5 With peripheral circulatory complications
0.000 0.564 0.435
E13.4 With neurological complications
0.000 0.564 0.435
E13.3 With ophthalmic complications
0.000 0.564 0.435
E13.2 With renal complications
0.000 0.564 0.435
E13.1 With ketoacidosis
0.000 0.564 0.435
E13.0 With coma
0.000 0.564 0.435
E22.0 Acromegaly and pituitary gigantism
0.000 0.568 0.432
L41.9 Parapsoriasis, unspecified
0.431 0.569 0.000
L41.8 Other parapsoriasis
0.431 0.569 0.000
L41.5 Retiform parapsoriasis
0.431 0.569 0.000
L41.4 Large plaque parapsoriasis
0.431 0.569 0.000
L41.3 Small plaque parapsoriasis
0.431 0.569 0.000
L41.2 Lymphomatoid papulosis
0.431 0.569 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.431 0.569 0.000
E06.3 Autoimmune thyroiditis
0.000 0.573 0.427
E23.6 Other disorders of pituitary gland
0.000 0.577 0.422
C82.1 Mixed small cleaved and large cell, follicular
0.422 0.578 0.000
C82.4 Follicular lymphoma grade IIIb
0.421 0.579 0.000
E26.0 Primary hyperaldosteronism
0.000 0.582 0.418
L43.9 Lichen planus, unspecified
0.407 0.593 0.000
C82.3 Follicular lymphoma grade IIIa
0.405 0.595 0.000
C82.2 Large cell, follicular
0.398 0.602 0.000
E34.3 Short stature, not elsewhere classified
0.000 0.604 0.396
L44.9 Papulosquamous disorder, unspecified
0.392 0.608 0.000
L44.8 Other specified papulosquamous disorders
0.392 0.608 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.392 0.608 0.000
L44.3 Lichen ruber moniliformis
0.392 0.608 0.000
L44.2 Lichen striatus
0.392 0.608 0.000
L44.1 Lichen nitidus
0.392 0.608 0.000
L44.0 Pityriasis rubra pilaris
0.392 0.608 0.000
E06.4 Drug-induced thyroiditis
0.000 0.609 0.390
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.609 0.390
E06.0 Acute thyroiditis
0.000 0.609 0.390
L43.3 Subacute (active) lichen planus
0.383 0.617 0.000
L43.2 Lichenoid drug reaction
0.383 0.617 0.000
L43.1 Bullous lichen planus
0.383 0.617 0.000
L43.0 Hypertrophic lichen planus
0.383 0.617 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.620 0.380
E29.8 Other testicular dysfunction
0.000 0.620 0.380
E29.0 Testicular hyperfunction
0.000 0.620 0.380
E53 Deficiency of other B group vitamins
0.000 0.624 0.376
E24 Cushing's syndrome
0.001 0.625 0.374
C82.6 Cutaneous follicle centre lymphoma
0.373 0.627 0.000
C82.5 Diffuse follicle centre lymphoma
0.373 0.627 0.000
E65 Localised adiposity
0.000 0.633 0.367
E06.5 Other chronic thyroiditis
0.000 0.633 0.366
E34.0 Carcinoid syndrome
0.000 0.636 0.363
E67 Other hyperalimentation
0.000 0.643 0.357
E68 Sequelae of hyperalimentation
0.000 0.643 0.357
E44.1 Mild protein-energy malnutrition
0.000 0.646 0.353
E44.0 Moderate protein-energy malnutrition
0.000 0.646 0.353
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.647 0.353
E51 Thiamine deficiency
0.000 0.652 0.348
L43.8 Other lichen planus
0.340 0.660 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.665 0.335
E63 Other nutritional deficiencies
0.000 0.665 0.335
E50 Vitamin A deficiency
0.000 0.665 0.335
E60 Dietary zinc deficiency
0.000 0.665 0.335
E59 Dietary selenium deficiency
0.000 0.665 0.335
E54 Ascorbic acid deficiency
0.000 0.665 0.335
E52 Niacin deficiency [pellagra]
0.000 0.665 0.335
E56 Other vitamin deficiencies
0.000 0.669 0.331
E13.9 Without complications
0.000 0.674 0.326
M07.6 Other enteropathic arthropathies
0.320 0.680 0.000
M07.5 Arthropathy in ulcerative colitis
0.320 0.680 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.320 0.680 0.000
M07.2 Psoriatic spondylitis
0.320 0.680 0.000
M07.1 Arthritis mutilans
0.320 0.680 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.320 0.680 0.000
E06.9 Thyroiditis, unspecified
0.000 0.693 0.307
E06.1 Subacute thyroiditis
0.001 0.695 0.305
E53.8 Deficiency of other specified B group vitamins
0.000 0.696 0.304
E58 Dietary calcium deficiency
0.000 0.711 0.289
E53.9 Vitamin B deficiency, unspecified
0.000 0.720 0.280
E53.1 Pyridoxine deficiency
0.000 0.730 0.270
E53.0 Riboflavin deficiency
0.000 0.730 0.270
E24.8 Other Cushing's syndrome
0.001 0.731 0.268
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.731 0.268
E24.3 Ectopic ACTH syndrome
0.001 0.731 0.268
E24.1 Nelson's syndrome
0.001 0.731 0.268
E51.2 Wernicke's encephalopathy
0.000 0.737 0.263
E67.8 Other specified hyperalimentation
0.000 0.744 0.256
E67.3 Hypervitaminosis D
0.000 0.744 0.256
E67.2 Megavitamin-B6 syndrome
0.000 0.744 0.256
E67.1 Hypercarotenaemia
0.000 0.744 0.256
E67.0 Hypervitaminosis A
0.000 0.744 0.256
E55 Vitamin D deficiency
0.000 0.747 0.253
E24.2 Drug-induced Cushing's syndrome
0.001 0.748 0.250
E51.9 Thiamine deficiency, unspecified
0.000 0.750 0.250
E51.8 Other manifestations of thiamine deficiency
0.000 0.750 0.250
E51.1 Beriberi
0.000 0.750 0.250
E50.9 Vitamin A deficiency, unspecified
0.000 0.760 0.240
E50.8 Other manifestations of vitamin A deficiency
0.000 0.760 0.240
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.760 0.240
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.760 0.240
E50.5 Vitamin A deficiency with night blindness
0.000 0.760 0.240
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.760 0.240
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.760 0.240
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.760 0.240
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.760 0.240
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.760 0.240
E63.9 Nutritional deficiency, unspecified
0.000 0.760 0.240
E63.8 Other specified nutritional deficiencies
0.000 0.760 0.240
E63.1 Imbalance of constituents of food intake
0.000 0.760 0.240
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.760 0.240
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.760 0.240
E64.8 Sequelae of other nutritional deficiencies
0.000 0.760 0.240
E64.3 Sequelae of rickets
0.000 0.760 0.240
E64.2 Sequelae of vitamin C deficiency
0.000 0.760 0.240
E64.1 Sequelae of vitamin A deficiency
0.000 0.760 0.240
E64.0 Sequelae of protein-energy malnutrition
0.000 0.760 0.240
E56.9 Vitamin deficiency, unspecified
0.000 0.762 0.237
E56.8 Deficiency of other vitamins
0.000 0.762 0.237
E56.0 Deficiency of vitamin E
0.000 0.762 0.237
E07.9 Disorder of thyroid, unspecified
0.000 0.765 0.235
E56.1 Deficiency of vitamin K
0.000 0.767 0.233
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.229 0.770 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.229 0.770 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.229 0.770 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.229 0.770 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.229 0.770 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.229 0.770 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.229 0.770 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.229 0.770 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.229 0.770 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.229 0.770 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.229 0.770 0.000
M07.18 Arthritis mutilans (Other)
0.229 0.770 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.229 0.770 0.000
M07.16 Arthritis mutilans (Lower leg)
0.229 0.770 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.229 0.770 0.000
M07.14 Arthritis mutilans (Hand)
0.229 0.770 0.000
M07.13 Arthritis mutilans (Forearm)
0.229 0.770 0.000
M07.12 Arthritis mutilans (Upper arm)
0.229 0.770 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.229 0.770 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.229 0.770 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.229 0.770 0.000
M07.28 Psoriatic spondylitis (Other)
0.229 0.770 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.229 0.770 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.229 0.770 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.229 0.770 0.000
M07.24 Psoriatic spondylitis (Hand)
0.229 0.770 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.229 0.770 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.229 0.770 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.229 0.770 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.229 0.770 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.229 0.770 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.229 0.770 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.229 0.770 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.229 0.770 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.229 0.770 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.229 0.770 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.229 0.770 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.229 0.770 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.229 0.770 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.229 0.770 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.229 0.770 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.229 0.770 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.229 0.770 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.229 0.770 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.229 0.770 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.229 0.770 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.229 0.770 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.229 0.770 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.229 0.770 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.229 0.770 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.229 0.770 0.000
M07.68 Other enteropathic arthropathies (Other)
0.229 0.770 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.229 0.770 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.229 0.770 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.229 0.770 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.229 0.770 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.229 0.770 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.229 0.770 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.229 0.770 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.229 0.770 0.000
E24.0 Pituitary-dependent Cushing's disease
0.001 0.784 0.214
E29.1 Testicular hypofunction
0.001 0.804 0.195
E61 Deficiency of other nutrient elements
0.001 0.806 0.193
E04 Other non-toxic goitre
0.000 0.808 0.192
E55.0 Rickets, active
0.000 0.819 0.181
E28.2 Polycystic ovarian syndrome
0.001 0.827 0.173
E23.0 Hypopituitarism
0.000 0.835 0.164
E11 Non-insulin-dependent diabetes mellitus
0.000 0.845 0.155
E04.0 Non-toxic diffuse goitre
0.000 0.855 0.145
E61.9 Deficiency of nutrient element, unspecified
0.001 0.861 0.139
E61.8 Deficiency of other specified nutrient elements
0.001 0.861 0.139
E61.7 Deficiency of multiple nutrient elements
0.001 0.861 0.139
E61.6 Vanadium deficiency
0.001 0.861 0.139
E61.5 Molybdenum deficiency
0.001 0.861 0.139
E61.4 Chromium deficiency
0.001 0.861 0.139
E61.3 Manganese deficiency
0.001 0.861 0.139
E61.0 Copper deficiency
0.001 0.861 0.139
E04.8 Other specified non-toxic goitre
0.000 0.862 0.138
E11.5 With peripheral circulatory complications
0.000 0.867 0.133
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.869 0.131
E24.9 Cushing's syndrome, unspecified
0.002 0.877 0.121
E61.2 Magnesium deficiency
0.001 0.878 0.121
E11.3 With ophthalmic complications
0.000 0.880 0.120
E04.1 Non-toxic single thyroid nodule
0.000 0.887 0.113
E66 Obesity
0.000 0.887 0.113
E11.7 With multiple complications
0.000 0.888 0.112
M45-M49 Spondylopathies
0.108 0.892 0.000
E11.8 With unspecified complications
0.000 0.894 0.106
E11.1 With ketoacidosis
0.000 0.899 0.101
D69.6 Thrombocytopenia, unspecified
0.000 0.901 0.099
E55.9 Vitamin D deficiency, unspecified
0.000 0.901 0.099
D69 Purpura and other haemorrhagic conditions
0.000 0.902 0.098
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.903 0.097
E11.6 With other specified complications
0.000 0.903 0.097
E11.0 With coma
0.000 0.905 0.095
D69.5 Secondary thrombocytopenia
0.000 0.913 0.087
E21.4 Other specified disorders of parathyroid gland
0.000 0.914 0.085
E66.0 Obesity due to excess calories
0.000 0.918 0.082
E11.2 With renal complications
0.000 0.918 0.082
E66.1 Drug-induced obesity
0.000 0.919 0.081
E21.2 Other hyperparathyroidism
0.000 0.922 0.078
D69.0 Allergic purpura
0.000 0.923 0.077
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.923 0.076
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.923 0.076
D69.4 Other primary thrombocytopenia
0.000 0.924 0.076
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.924 0.076
D69.2 Other nonthrombocytopenic purpura
0.000 0.925 0.075
G35 Multiple sclerosis
0.000 0.926 0.074
E21.3 Hyperparathyroidism, unspecified
0.000 0.929 0.071
D69.8 Other specified haemorrhagic conditions
0.000 0.929 0.071
D69.1 Qualitative platelet defects
0.000 0.933 0.067
M49 Spondylopathies in diseases classified elsewhere
0.067 0.933 0.000
K90-K93 Other diseases of the digestive system
0.000 0.933 0.067
M35.0 Sicca syndrome [Sjogren]
0.000 0.937 0.063
D69.9 Haemorrhagic condition, unspecified
0.000 0.939 0.060
J33.0 Polyp of nasal cavity
0.000 0.940 0.060
M35 Other systemic involvement of connective tissue
0.000 0.940 0.060
E11.4 With neurological complications
0.000 0.941 0.059
M35.3 Polymyalgia rheumatica
0.000 0.941 0.059
M48 Other spondylopathies
0.057 0.943 0.000
M46 Other inflammatory spondylopathies
0.057 0.943 0.000
H20.9 Iridocyclitis, unspecified
0.054 0.946 0.000
M35.1 Other overlap syndromes
0.000 0.948 0.052
M05-M14 Inflammatory polyarthropathies
0.049 0.951 0.000
K59.8 Other specified functional intestinal disorders
0.049 0.951 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.048 0.952 0.000
M49.4 Neuropathic spondylopathy
0.048 0.952 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.048 0.952 0.000
M49.2 Enterobacterial spondylitis
0.048 0.952 0.000
M49.1 Brucella spondylitis
0.048 0.952 0.000
M49.0 Tuberculosis of spine
0.048 0.952 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.952 0.048
M46.4 Discitis, unspecified
0.048 0.952 0.000
M48.9 Spondylopathy, unspecified
0.047 0.953 0.000
M35.8 Other specified systemic involvement of connective tissue
0.000 0.953 0.047
E61.1 Iron deficiency
0.001 0.954 0.045
D86.9 Sarcoidosis, unspecified
0.000 0.954 0.046
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.957 0.043
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.957 0.043
M35.5 Multifocal fibrosclerosis
0.000 0.957 0.043
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.957 0.043
M48.8 Other specified spondylopathies
0.043 0.957 0.000
M35.2 Behcet's disease
0.000 0.958 0.042
M48.4 Fatigue fracture of vertebra
0.041 0.959 0.000
M48.3 Traumatic spondylopathy
0.041 0.959 0.000
M48.2 Kissing spine
0.041 0.959 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.041 0.959 0.000
M46.8 Other specified inflammatory spondylopathies
0.041 0.959 0.000
M46.5 Other infective spondylopathies
0.041 0.959 0.000
M46.2 Osteomyelitis of vertebra
0.041 0.959 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.041 0.959 0.000
M48.99 Spondylopathy, unspecified (Site unspecified)
0.039 0.961 0.000
M47 Spondylosis
0.039 0.961 0.000
M11 Other crystal arthropathies
0.039 0.961 0.000
M08 Juvenile arthritis
0.038 0.961 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.038 0.962 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.038 0.962 0.000
M35.7 Hypermobility syndrome
0.000 0.962 0.038
M48.5 Collapsed vertebra, not elsewhere classified
0.038 0.962 0.000
M48.92 Spondylopathy, unspecified (Cervical region)
0.037 0.963 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.037 0.963 0.000
D86 Sarcoidosis
0.000 0.963 0.037
M46.46 Discitis, unspecified (Lumbar region)
0.036 0.963 0.000
M46.0 Spinal enthesopathy
0.036 0.963 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.036 0.964 0.000
M46.42 Discitis, unspecified (Cervical region)
0.036 0.964 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.964 0.036
M09 Juvenile arthritis in diseases classified elsewhere
0.036 0.964 0.000
M47.8 Other spondylosis
0.036 0.964 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.965 0.035
M49.09 Tuberculosis of spine (Site unspecified)
0.035 0.965 0.000
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.035 0.965 0.000
M49.07 Tuberculosis of spine (Lumbosacral region)
0.035 0.965 0.000
M49.06 Tuberculosis of spine (Lumbar region)
0.035 0.965 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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