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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2428486
log Bayes Factor = 82.6568
Chromosome 6   position 31,354,104  (GRCh37) Explore rs2428486 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.999 0.001 0.000
M07.3 Other psoriatic arthropathies
0.999 0.001 0.000
M45 Ankylosing spondylitis
0.999 0.001 0.000
E00-E07 Disorders of thyroid gland
0.000 0.002 0.998
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.998 0.002 0.000
E27 Other disorders of adrenal gland
0.000 0.004 0.996
E10.3 With ophthalmic complications
0.000 0.004 0.996
M07.39 Other psoriatic arthropathies (Site unspecified)
0.996 0.004 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.004 0.996
E20-E35 Disorders of other endocrine glands
0.000 0.005 0.995
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.005 0.995
E03 Other hypothyroidism
0.000 0.005 0.995
E03.9 Hypothyroidism, unspecified
0.000 0.007 0.993
L40.0 Psoriasis vulgaris
0.992 0.008 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.008 0.992
E16.2 Hypoglycaemia, unspecified
0.000 0.012 0.988
E10.1 With ketoacidosis
0.000 0.016 0.984
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.016 0.984
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.042 0.958
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.052 0.948
E10.4 With neurological complications
0.000 0.063 0.937
E05.9 Thyrotoxicosis, unspecified
0.000 0.069 0.931
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.929 0.071 0.000
E10.0 With coma
0.000 0.080 0.920
E14 Unspecified diabetes mellitus
0.000 0.103 0.897
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.107 0.893
E27.2 Addisonian crisis
0.000 0.127 0.873
E20 Hypoparathyroidism
0.000 0.136 0.864
M07.34 Other psoriatic arthropathies (Hand)
0.860 0.140 0.000
K90 Intestinal malabsorption
0.000 0.149 0.851
L40.4 Guttate psoriasis
0.847 0.153 0.000
E10.2 With renal complications
0.000 0.176 0.824
E14.9 Without complications
0.000 0.181 0.819
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.808 0.191 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.200 0.800
M45.X6 Ankylosing spondylitis (Lumbar region)
0.793 0.207 0.000
M07.38 Other psoriatic arthropathies (Other)
0.792 0.208 0.000
L40.1 Generalised pustular psoriasis
0.777 0.223 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.774 0.226 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.231 0.769
M45.X2 Ankylosing spondylitis (Cervical region)
0.759 0.241 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.241 0.759
E10.5 With peripheral circulatory complications
0.000 0.250 0.750
L40-L45 Papulosquamous disorders
0.748 0.252 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.747 0.253 0.000
L40.8 Other psoriasis
0.738 0.262 0.000
E10.6 With other specified complications
0.000 0.262 0.738
K90.8 Other intestinal malabsorption
0.000 0.271 0.729
E10.7 With multiple complications
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
M07.33 Other psoriatic arthropathies (Forearm)
0.716 0.284 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.716 0.284 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.716 0.284 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.716 0.284 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.716 0.284 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.716 0.284 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.716 0.284 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.716 0.284 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E27.5 Adrenomedullary hyperfunction
0.000 0.286 0.714
E27.0 Other adrenocortical overactivity
0.000 0.286 0.714
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.286 0.714
E32 Diseases of thymus
0.000 0.286 0.714
E31 Polyglandular dysfunction
0.000 0.286 0.714
E30 Disorders of puberty, not elsewhere classified
0.000 0.286 0.714
E15 Nondiabetic hypoglycaemic coma
0.000 0.286 0.714
E03.5 Myxoedema coma
0.000 0.287 0.713
E03.4 Atrophy of thyroid (acquired)
0.000 0.287 0.713
E03.3 Postinfectious hypothyroidism
0.000 0.287 0.713
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.289 0.711
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.289 0.711
E16.4 Abnormal secretion of gastrin
0.000 0.289 0.711
E16.3 Increased secretion of glucagon
0.000 0.289 0.711
E05.5 Thyroid crisis or storm
0.000 0.294 0.706
E05.4 Thyrotoxicosis factitia
0.000 0.294 0.706
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.294 0.706
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.294 0.706
E03.1 Congenital hypothyroidism without goitre
0.000 0.299 0.701
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.303 0.697
E14.6 With other specified complications
0.000 0.306 0.694
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.307 0.692
L42 Pityriasis rosea
0.688 0.312 0.000
E25 Adrenogenital disorders
0.000 0.312 0.688
E14.2 Withrenal complications
0.000 0.315 0.685
L40.3 Pustulosis palmaris et plantaris
0.684 0.316 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.320 0.680
E27.8 Other specified disorders of adrenal gland
0.000 0.322 0.678
E14.1 With ketoacidosis
0.000 0.326 0.674
E34 Other endocrine disorders
0.000 0.331 0.669
E23 Hypofunction and other disorders of pituitary gland
0.000 0.334 0.666
E22 Hyperfunction of pituitary gland
0.000 0.342 0.658
E14.5 With peripheral circulatory complications
0.000 0.345 0.655
E07 Other disorders of thyroid
0.000 0.347 0.653
E40-E46 Malnutrition
0.000 0.347 0.653
E10.8 With unspecified complications
0.000 0.348 0.652
E26 Hyperaldosteronism
0.000 0.354 0.646
E14.7 With multiple complications
0.000 0.356 0.643
E14.0 With coma
0.000 0.356 0.643
E03.8 Other specified hypothyroidism
0.000 0.366 0.634
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.380 0.619
E20.8 Other hypoparathyroidism
0.000 0.381 0.619
E20.1 Pseudohypoparathyroidism
0.000 0.381 0.619
E20.0 Idiopathic hypoparathyroidism
0.000 0.381 0.619
E14.8 With unspecified complications
0.000 0.385 0.615
E05.8 Other thyrotoxicosis
0.000 0.386 0.614
E28 Ovarian dysfunction
0.000 0.386 0.614
K90.3 Pancreatic steatorrhoea
0.000 0.390 0.610
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.390 0.610
K90.1 Tropical sprue
0.000 0.390 0.610
E13 Other specified diabetes mellitus
0.000 0.401 0.599
E14.3 With ophthalmic complications
0.000 0.407 0.593
L41 Parapsoriasis
0.591 0.409 0.000
E14.4 With neurological complications
0.000 0.417 0.582
E23.2 Diabetes insipidus
0.000 0.418 0.582
E06 Thyroiditis
0.000 0.439 0.561
E29 Testicular dysfunction
0.000 0.449 0.550
E07.8 Other specified disorders of thyroid
0.000 0.451 0.549
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.452 0.548
E34.9 Endocrine disorder, unspecified
0.000 0.459 0.540
E16.1 Other hypoglycaemia
0.000 0.463 0.537
L44 Other papulosquamous disorders
0.537 0.463 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.537 0.463 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.473 0.527
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.487 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.487 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.487 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.487 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.487 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.487 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.487 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.487 0.513
E34.8 Other specified endocrine disorders
0.000 0.487 0.513
E30.9 Disorder of puberty, unspecified
0.000 0.488 0.512
E30.8 Other disorders of puberty
0.000 0.488 0.512
E30.1 Precocious puberty
0.000 0.488 0.512
E30.0 Delayed puberty
0.000 0.488 0.512
E31.9 Polyglandular dysfunction, unspecified
0.000 0.488 0.512
E31.8 Other polyglandular dysfunction
0.000 0.488 0.512
E31.1 Polyglandular hyperfunction
0.000 0.488 0.512
E31.0 Autoimmune polyglandular failure
0.000 0.488 0.512
E32.9 Disease of thymus, unspecified
0.000 0.488 0.512
E32.8 Other diseases of thymus
0.000 0.488 0.512
E32.1 Abscess of thymus
0.000 0.488 0.512
E32.0 Persistent hyperplasia of thymus
0.000 0.488 0.512
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.488 0.512
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.488 0.512
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.488 0.512
E23.7 Disorder of pituitary gland, unspecified
0.000 0.491 0.509
E22.1 Hyperprolactinaemia
0.000 0.492 0.508
L43 Lichen planus
0.507 0.493 0.000
E28.3 Primary ovarian failure
0.000 0.493 0.507
E25.9 Adrenogenital disorder, unspecified
0.000 0.506 0.493
E25.8 Other adrenogenital disorders
0.000 0.506 0.493
E34.5 Androgen resistance syndrome
0.000 0.520 0.479
E34.4 Constitutional tall stature
0.000 0.520 0.479
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.520 0.479
E34.1 Other hypersecretion of intestinal hormones
0.000 0.520 0.479
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.522 0.477
E23.1 Drug-induced hypopituitarism
0.000 0.522 0.477
L41.1 Pityriasis lichenoides chronica
0.478 0.522 0.000
E50-E64 Other nutritional deficiencies
0.000 0.527 0.473
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.528 0.472
E22.8 Other hyperfunction of pituitary gland
0.000 0.528 0.472
E07.1 Dyshormogenetic goitre
0.000 0.532 0.468
E07.0 Hypersecretion of calcitonin
0.000 0.532 0.468
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.532 0.468
E45 Retarded development following protein-energy malnutrition
0.000 0.532 0.468
E43 Unspecified severe protein-energy malnutrition
0.000 0.532 0.468
E42 Marasmic kwashiorkor
0.000 0.532 0.468
E41 Nutritional marasmus
0.000 0.532 0.468
E40 Kwashiorkor
0.000 0.532 0.468
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.532 0.468
E26.8 Other hyperaldosteronism
0.000 0.537 0.463
E26.1 Secondary hyperaldosteronism
0.000 0.537 0.463
E27.9 Disorder of adrenal gland, unspecified
0.001 0.547 0.452
M07 Psoriatic and enteropathic arthropathies
0.452 0.548 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.552 0.448
E26.9 Hyperaldosteronism, unspecified
0.000 0.555 0.444
E28.9 Ovarian dysfunction, unspecified
0.000 0.559 0.440
E28.8 Other ovarian dysfunction
0.000 0.559 0.440
E28.1 Androgen excess
0.000 0.559 0.440
E28.0 Oestrogen excess
0.000 0.559 0.440
E06.3 Autoimmune thyroiditis
0.000 0.560 0.440
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.438 0.562 0.000
E13.8 With unspecified complications
0.000 0.570 0.430
E13.7 With multiple complications
0.000 0.570 0.430
E13.6 With other specified complications
0.000 0.570 0.430
E13.5 With peripheral circulatory complications
0.000 0.570 0.430
E13.4 With neurological complications
0.000 0.570 0.430
E13.3 With ophthalmic complications
0.000 0.570 0.430
E13.2 With renal complications
0.000 0.570 0.430
E13.1 With ketoacidosis
0.000 0.570 0.430
E13.0 With coma
0.000 0.570 0.430
E23.6 Other disorders of pituitary gland
0.000 0.575 0.425
L41.9 Parapsoriasis, unspecified
0.423 0.576 0.000
L41.8 Other parapsoriasis
0.423 0.576 0.000
L41.5 Retiform parapsoriasis
0.423 0.576 0.000
L41.4 Large plaque parapsoriasis
0.423 0.576 0.000
L41.3 Small plaque parapsoriasis
0.423 0.576 0.000
L41.2 Lymphomatoid papulosis
0.423 0.576 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.423 0.576 0.000
E26.0 Primary hyperaldosteronism
0.000 0.582 0.418
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.415 0.585 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.596 0.404
E34.3 Short stature, not elsewhere classified
0.000 0.597 0.402
E06.4 Drug-induced thyroiditis
0.000 0.598 0.402
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.598 0.402
E06.0 Acute thyroiditis
0.000 0.598 0.402
E65 Localised adiposity
0.000 0.598 0.402
E29.9 Testicular dysfunction, unspecified
0.000 0.605 0.395
E29.8 Other testicular dysfunction
0.000 0.605 0.395
E29.0 Testicular hyperfunction
0.000 0.605 0.395
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.608 0.392
L44.9 Papulosquamous disorder, unspecified
0.385 0.615 0.000
L44.8 Other specified papulosquamous disorders
0.385 0.615 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.385 0.615 0.000
L44.3 Lichen ruber moniliformis
0.385 0.615 0.000
L44.2 Lichen striatus
0.385 0.615 0.000
L44.1 Lichen nitidus
0.385 0.615 0.000
L44.0 Pityriasis rubra pilaris
0.385 0.615 0.000
C82.0 Small cleaved cell, follicular
0.381 0.619 0.000
E53 Deficiency of other B group vitamins
0.000 0.621 0.379
E67 Other hyperalimentation
0.000 0.622 0.378
E68 Sequelae of hyperalimentation
0.000 0.622 0.378
E06.5 Other chronic thyroiditis
0.000 0.622 0.377
E24 Cushing's syndrome
0.001 0.625 0.374
L43.9 Lichen planus, unspecified
0.373 0.627 0.000
E34.0 Carcinoid syndrome
0.000 0.630 0.369
L43.3 Subacute (active) lichen planus
0.364 0.636 0.000
L43.2 Lichenoid drug reaction
0.364 0.636 0.000
L43.1 Bullous lichen planus
0.364 0.636 0.000
L43.0 Hypertrophic lichen planus
0.364 0.636 0.000
E51 Thiamine deficiency
0.000 0.647 0.353
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.351 0.648 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.342 0.657 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.661 0.339
E63 Other nutritional deficiencies
0.000 0.661 0.339
E50 Vitamin A deficiency
0.000 0.661 0.339
E60 Dietary zinc deficiency
0.000 0.661 0.339
E59 Dietary selenium deficiency
0.000 0.661 0.339
E54 Ascorbic acid deficiency
0.000 0.661 0.339
E52 Niacin deficiency [pellagra]
0.000 0.661 0.339
C82.4 Follicular lymphoma grade IIIb
0.336 0.664 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.664 0.336
E44.0 Moderate protein-energy malnutrition
0.000 0.664 0.336
E56 Other vitamin deficiencies
0.000 0.665 0.335
E06.9 Thyroiditis, unspecified
0.000 0.667 0.333
M07.6 Other enteropathic arthropathies
0.324 0.676 0.000
M07.5 Arthropathy in ulcerative colitis
0.324 0.676 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.324 0.676 0.000
M07.2 Psoriatic spondylitis
0.324 0.676 0.000
M07.1 Arthritis mutilans
0.324 0.676 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.324 0.676 0.000
C82.3 Follicular lymphoma grade IIIa
0.323 0.677 0.000
L43.8 Other lichen planus
0.323 0.677 0.000
C82.2 Large cell, follicular
0.317 0.683 0.000
E06.1 Subacute thyroiditis
0.000 0.686 0.314
E13.9 Without complications
0.000 0.688 0.312
E53.8 Deficiency of other specified B group vitamins
0.000 0.696 0.304
C82.6 Cutaneous follicle centre lymphoma
0.297 0.702 0.000
C82.5 Diffuse follicle centre lymphoma
0.297 0.702 0.000
E58 Dietary calcium deficiency
0.000 0.707 0.293
E53.9 Vitamin B deficiency, unspecified
0.000 0.718 0.282
E11 Non-insulin-dependent diabetes mellitus
0.000 0.727 0.273
E53.1 Pyridoxine deficiency
0.000 0.728 0.271
E53.0 Riboflavin deficiency
0.000 0.728 0.271
E67.8 Other specified hyperalimentation
0.000 0.729 0.271
E67.3 Hypervitaminosis D
0.000 0.729 0.271
E67.2 Megavitamin-B6 syndrome
0.000 0.729 0.271
E67.1 Hypercarotenaemia
0.000 0.729 0.271
E67.0 Hypervitaminosis A
0.000 0.729 0.271
E24.8 Other Cushing's syndrome
0.001 0.731 0.268
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.731 0.268
E24.3 Ectopic ACTH syndrome
0.001 0.731 0.268
E24.1 Nelson's syndrome
0.001 0.731 0.268
E51.2 Wernicke's encephalopathy
0.000 0.733 0.266
E55 Vitamin D deficiency
0.000 0.735 0.265
E51.9 Thiamine deficiency, unspecified
0.000 0.747 0.253
E51.8 Other manifestations of thiamine deficiency
0.000 0.747 0.253
E51.1 Beriberi
0.000 0.747 0.253
E24.2 Drug-induced Cushing's syndrome
0.001 0.748 0.250
E50.9 Vitamin A deficiency, unspecified
0.000 0.756 0.243
E50.8 Other manifestations of vitamin A deficiency
0.000 0.756 0.243
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.756 0.243
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.756 0.243
E50.5 Vitamin A deficiency with night blindness
0.000 0.756 0.243
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.756 0.243
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.756 0.243
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.756 0.243
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.756 0.243
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.756 0.243
E63.9 Nutritional deficiency, unspecified
0.000 0.756 0.243
E63.8 Other specified nutritional deficiencies
0.000 0.756 0.243
E63.1 Imbalance of constituents of food intake
0.000 0.756 0.243
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.756 0.243
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.756 0.243
E64.8 Sequelae of other nutritional deficiencies
0.000 0.756 0.243
E64.3 Sequelae of rickets
0.000 0.756 0.243
E64.2 Sequelae of vitamin C deficiency
0.000 0.756 0.243
E64.1 Sequelae of vitamin A deficiency
0.000 0.756 0.243
E64.0 Sequelae of protein-energy malnutrition
0.000 0.756 0.243
E56.9 Vitamin deficiency, unspecified
0.000 0.759 0.240
E56.8 Deficiency of other vitamins
0.000 0.759 0.240
E56.0 Deficiency of vitamin E
0.000 0.759 0.240
E11.5 With peripheral circulatory complications
0.000 0.762 0.238
E56.1 Deficiency of vitamin K
0.000 0.763 0.236
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.233 0.767 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.233 0.767 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.233 0.767 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.233 0.767 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.233 0.767 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.233 0.767 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.233 0.767 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.233 0.767 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.233 0.767 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.233 0.767 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.233 0.767 0.000
M07.18 Arthritis mutilans (Other)
0.233 0.767 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.233 0.767 0.000
M07.16 Arthritis mutilans (Lower leg)
0.233 0.767 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.233 0.767 0.000
M07.14 Arthritis mutilans (Hand)
0.233 0.767 0.000
M07.13 Arthritis mutilans (Forearm)
0.233 0.767 0.000
M07.12 Arthritis mutilans (Upper arm)
0.233 0.767 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.233 0.767 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.233 0.767 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.233 0.767 0.000
M07.28 Psoriatic spondylitis (Other)
0.233 0.767 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.233 0.767 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.233 0.767 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.233 0.767 0.000
M07.24 Psoriatic spondylitis (Hand)
0.233 0.767 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.233 0.767 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.233 0.767 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.233 0.767 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.233 0.767 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.233 0.767 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.233 0.767 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.233 0.767 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.233 0.767 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.233 0.767 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.233 0.767 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.233 0.767 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.233 0.767 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.233 0.767 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.233 0.767 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.233 0.767 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.233 0.767 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.233 0.767 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.233 0.767 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.233 0.767 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.233 0.767 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.233 0.767 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.233 0.767 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.233 0.767 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.233 0.767 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.233 0.767 0.000
M07.68 Other enteropathic arthropathies (Other)
0.233 0.767 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.233 0.767 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.233 0.767 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.233 0.767 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.233 0.767 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.233 0.767 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.233 0.767 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.233 0.767 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.233 0.767 0.000
E29.1 Testicular hypofunction
0.000 0.768 0.231
E11.3 With ophthalmic complications
0.000 0.782 0.218
E24.0 Pituitary-dependent Cushing's disease
0.001 0.784 0.214
E07.9 Disorder of thyroid, unspecified
0.000 0.787 0.213
E61 Deficiency of other nutrient elements
0.001 0.802 0.197
E11.7 With multiple complications
0.000 0.804 0.196
E04 Other non-toxic goitre
0.000 0.808 0.192
E55.0 Rickets, active
0.000 0.810 0.190
E11.8 With unspecified complications
0.000 0.811 0.189
E11.6 With other specified complications
0.000 0.822 0.178
E11.1 With ketoacidosis
0.000 0.822 0.178
E11.0 With coma
0.000 0.825 0.174
E23.0 Hypopituitarism
0.000 0.828 0.172
E28.2 Polycystic ovarian syndrome
0.001 0.828 0.172
E11.2 With renal complications
0.000 0.837 0.163
E04.0 Non-toxic diffuse goitre
0.000 0.850 0.150
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.851 0.148
E61.9 Deficiency of nutrient element, unspecified
0.001 0.858 0.141
E61.8 Deficiency of other specified nutrient elements
0.001 0.858 0.141
E61.7 Deficiency of multiple nutrient elements
0.001 0.858 0.141
E61.6 Vanadium deficiency
0.001 0.858 0.141
E61.5 Molybdenum deficiency
0.001 0.858 0.141
E61.4 Chromium deficiency
0.001 0.858 0.141
E61.3 Manganese deficiency
0.001 0.858 0.141
E61.0 Copper deficiency
0.001 0.858 0.141
E04.8 Other specified non-toxic goitre
0.000 0.862 0.138
D69 Purpura and other haemorrhagic conditions
0.000 0.870 0.130
D69.6 Thrombocytopenia, unspecified
0.000 0.870 0.130
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.870 0.130
E61.2 Magnesium deficiency
0.001 0.876 0.124
E66 Obesity
0.000 0.876 0.124
E24.9 Cushing's syndrome, unspecified
0.002 0.877 0.121
M45-M49 Spondylopathies
0.120 0.880 0.000
E11.4 With neurological complications
0.000 0.880 0.119
E55.9 Vitamin D deficiency, unspecified
0.000 0.884 0.116
D69.5 Secondary thrombocytopenia
0.000 0.884 0.116
D69.0 Allergic purpura
0.000 0.893 0.107
E04.1 Non-toxic single thyroid nodule
0.000 0.894 0.106
D69.4 Other primary thrombocytopenia
0.000 0.899 0.101
D69.2 Other nonthrombocytopenic purpura
0.000 0.900 0.100
E21.4 Other specified disorders of parathyroid gland
0.000 0.903 0.097
D69.8 Other specified haemorrhagic conditions
0.000 0.906 0.093
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.909 0.091
E66.0 Obesity due to excess calories
0.000 0.910 0.090
D69.1 Qualitative platelet defects
0.000 0.911 0.089
E21.2 Other hyperparathyroidism
0.000 0.911 0.089
E66.1 Drug-induced obesity
0.000 0.911 0.089
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.913 0.086
E21.3 Hyperparathyroidism, unspecified
0.000 0.914 0.086
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.916 0.084
D69.9 Haemorrhagic condition, unspecified
0.000 0.920 0.080
M49 Spondylopathies in diseases classified elsewhere
0.075 0.925 0.000
K90-K93 Other diseases of the digestive system
0.000 0.931 0.069
M46 Other inflammatory spondylopathies
0.069 0.931 0.000
J33.0 Polyp of nasal cavity
0.000 0.932 0.068
M48 Other spondylopathies
0.064 0.936 0.000
M05-M14 Inflammatory polyarthropathies
0.060 0.940 0.000
M46.4 Discitis, unspecified
0.059 0.941 0.000
G35 Multiple sclerosis
0.000 0.942 0.058
M49.8 Spondylopathy in other diseases classified elsewhere
0.054 0.946 0.000
M49.4 Neuropathic spondylopathy
0.054 0.946 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.054 0.946 0.000
M49.2 Enterobacterial spondylitis
0.054 0.946 0.000
M49.1 Brucella spondylitis
0.054 0.946 0.000
M49.0 Tuberculosis of spine
0.054 0.946 0.000
M48.9 Spondylopathy, unspecified
0.053 0.947 0.000
D86.9 Sarcoidosis, unspecified
0.000 0.948 0.052
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.950 0.050
M46.8 Other specified inflammatory spondylopathies
0.049 0.950 0.000
M46.5 Other infective spondylopathies
0.049 0.950 0.000
M46.2 Osteomyelitis of vertebra
0.049 0.950 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.049 0.951 0.000
E61.1 Iron deficiency
0.001 0.952 0.047
M48.8 Other specified spondylopathies
0.048 0.952 0.000
M11 Other crystal arthropathies
0.047 0.953 0.000
M08 Juvenile arthritis
0.047 0.953 0.000
M48.4 Fatigue fracture of vertebra
0.046 0.954 0.000
M48.3 Traumatic spondylopathy
0.046 0.954 0.000
M48.2 Kissing spine
0.046 0.954 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.046 0.954 0.000
K59.8 Other specified functional intestinal disorders
0.046 0.954 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.046 0.954 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.046 0.954 0.000
D86 Sarcoidosis
0.000 0.955 0.045
M46.3 Infection of intervertebral disk (pyogenic)
0.044 0.955 0.000
M48.99 Spondylopathy, unspecified (Site unspecified)
0.044 0.956 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.044 0.956 0.000
M46.42 Discitis, unspecified (Cervical region)
0.044 0.956 0.000
M46.0 Spinal enthesopathy
0.044 0.956 0.000
H20.9 Iridocyclitis, unspecified
0.044 0.956 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.043 0.957 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.043 0.957 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.042 0.957 0.000
M46.40 Discitis, unspecified (Multiple sites in spine)
0.042 0.957 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.042 0.958 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.042 0.958 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.042 0.958 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.042 0.958 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.042 0.958 0.000
M48.92 Spondylopathy, unspecified (Cervical region)
0.042 0.958 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.040 0.960 0.000
D86.1 Sarcoidosis of lymph nodes
0.000 0.960 0.040
M48.87 Other specified spondylopathies (Lumbosacral region)
0.039 0.961 0.000
M49.09 Tuberculosis of spine (Site unspecified)
0.039 0.961 0.000
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.039 0.961 0.000
M49.07 Tuberculosis of spine (Lumbosacral region)
0.039 0.961 0.000
M49.06 Tuberculosis of spine (Lumbar region)
0.039 0.961 0.000
M49.05 Tuberculosis of spine (Thoracolumbar region)
0.039 0.961 0.000
M49.04 Tuberculosis of spine (Thoracic region)
0.039 0.961 0.000
M49.03 Tuberculosis of spine (Cervicothoracic region)
0.039 0.961 0.000
M49.02 Tuberculosis of spine (Cervical region)
0.039 0.961 0.000
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)
0.039 0.961 0.000
M49.00 Tuberculosis of spine (Multiple sites in spine)
0.039 0.961 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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