TreeWAS – Variant ID: rs2444240

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K22 Other diseases of oesophagus	0.986	0.014	0.000
K22.8 Other specified diseases of oesophagus	0.984	0.016	0.000
K22.5 Diverticulum of oesophagus, acquired	0.978	0.022	0.000
K22.9 Disease of oesophagus, unspecified	0.968	0.032	0.000
K22.7 Barrett's oesophagus	0.968	0.032	0.000
K22.4 Dyskinesia of oesophagus	0.875	0.125	0.000
K22.1 Ulcer of oesophagus	0.774	0.226	0.000
K22.3 Perforation of oesophagus	0.645	0.354	0.000
K22.0 Achalasia of cardia	0.520	0.480	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.419	0.581	0.000
K22.2 Oesophageal obstruction	0.321	0.679	0.000
K20 Oesophagitis	0.249	0.751	0.000
K20-K31 Diseases of oesophagus, stomach and duodenum	0.241	0.759	0.000
K26 Duodenal ulcer	0.203	0.797	0.000
K26.7 Chronic without haemorrhage or perforation	0.192	0.808	0.000
K31.5 Obstruction of duodenum	0.189	0.811	0.000
K31 Other diseases of stomach and duodenum	0.187	0.813	0.000
K26.5 Chronic or unspecified with perforation	0.176	0.824	0.000
K26.3 Acute without haemorrhage or perforation	0.176	0.824	0.000
K28 Gastrojejunal ulcer	0.165	0.835	0.000
K23 Disorders of oesophagus in diseases classified elsewhere	0.161	0.838	0.000
K31.1 Adult hypertrophic pyloric stenosis	0.152	0.848	0.000
K31.6 Fistula of stomach and duodenum	0.145	0.855	0.000
K31.2 Hourglass stricture and stenosis of stomach	0.139	0.861	0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.139	0.861	0.000
K26.1 Acute with perforation	0.137	0.863	0.000
K26.2 Acute with both haemorrhage and perforation	0.134	0.865	0.000
K31.0 Acute dilatation of stomach	0.133	0.867	0.000
K31.4 Gastric diverticulum	0.130	0.870	0.000
K31.3 Pylorospasm, not elsewhere classified	0.123	0.877	0.000
K26.0 Acute with haemorrhage	0.120	0.880	0.000
K28.7 Chronic without haemorrhage or perforation	0.119	0.881	0.000
K28.6 Chronic or unspecified with both haemorrhage and perforation	0.119	0.881	0.000
K28.5 Chronic or unspecified with perforation	0.119	0.881	0.000
K28.4 Chronic or unspecified with haemorrhage	0.119	0.881	0.000
K28.3 Acute without haemorrhage or perforation	0.119	0.881	0.000
K28.2 Acute with both haemorrhage and perforation	0.119	0.881	0.000
K28.1 Acute with perforation	0.119	0.881	0.000
K28.0 Acute with haemorrhage	0.119	0.881	0.000
K26.4 Chronic or unspecified with haemorrhage	0.118	0.882	0.000
K23.1 Megaoesophagus in Chagas' disease	0.116	0.884	0.000
K23.0 Tuberculous oesophagitis	0.116	0.884	0.000
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.111	0.889	0.000
K27 Peptic ulcer, site unspecified	0.104	0.895	0.001
K23.8 Disorders of oesophagus in other diseases classified elsewhere	0.104	0.896	0.000
K27.4 Chronic or unspecified with haemorrhage	0.083	0.916	0.000
K27.3 Acute without haemorrhage or perforation	0.082	0.918	0.000
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.075	0.925	0.001
K27.5 Chronic or unspecified with perforation	0.075	0.925	0.001
K27.2 Acute with both haemorrhage and perforation	0.075	0.925	0.001
K27.1 Acute with perforation	0.075	0.925	0.001
K27.0 Acute with haemorrhage	0.075	0.925	0.001
Z89.4 Acquired absence of foot and ankle	0.000	0.948	0.052
K27.7 Chronic without haemorrhage or perforation	0.049	0.950	0.001
Z89 Acquired absence of limb	0.000	0.951	0.049
Z89.5 Acquired absence of leg at or below knee	0.000	0.953	0.047
Z89.6 Acquired absence of leg above knee	0.000	0.955	0.044
K21 Gastro-oesophageal reflux disease	0.044	0.956	0.000
E10.5 With peripheral circulatory complications	0.000	0.956	0.044
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.000	0.957	0.043
E10 Insulin-dependent diabetes mellitus	0.000	0.958	0.042
E10.4 With neurological complications	0.000	0.958	0.042
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.000	0.962	0.038
E14 Unspecified diabetes mellitus	0.000	0.963	0.037
Z89.9 Acquired absence of limb, unspecified	0.000	0.963	0.037
E10.0 With coma	0.000	0.964	0.036
Z89.3 Acquired absence of both upper limbs [any level]	0.000	0.964	0.036
Z89.1 Acquired absence of hand and wrist	0.000	0.964	0.036
E10.6 With other specified complications	0.000	0.964	0.035
E14.9 Without complications	0.000	0.965	0.035
Z89.8 Acquired absence of upper and lower limbs [any level]	0.000	0.966	0.034
E10.1 With ketoacidosis	0.000	0.966	0.034
E14.4 With neurological complications	0.000	0.967	0.033
E10-E14 Diabetes mellitus	0.000	0.967	0.033
E10.8 With unspecified complications	0.000	0.967	0.032
E14.8 With unspecified complications	0.000	0.968	0.032
E14.5 With peripheral circulatory complications	0.000	0.969	0.031
Z89.2 Acquired absence of upper limb above wrist	0.000	0.969	0.031
E10.2 With renal complications	0.000	0.969	0.031
E10.7 With multiple complications	0.000	0.970	0.030
E14.6 With other specified complications	0.000	0.970	0.030
E14.3 With ophthalmic complications	0.000	0.971	0.029
K31.8 Other specified diseases of stomach and duodenum	0.028	0.972	0.000
E14.7 With multiple complications	0.000	0.973	0.027
E14.0 With coma	0.000	0.973	0.027
J31.0 Chronic rhinitis	0.027	0.973	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.976	0.024
E14.2 Withrenal complications	0.000	0.976	0.024
E14.1 With ketoacidosis	0.000	0.977	0.023
K25 Gastric ulcer	0.022	0.978	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.978	0.022
I10 Essential (primary) hypertension	0.020	0.980	0.000
E12.9 Without complications	0.000	0.982	0.017
E12.8 With unspecified complications	0.000	0.982	0.017
E12.7 With multiple complications	0.000	0.982	0.017
E12.6 With other specified complications	0.000	0.982	0.017
E12.5 With peripheral circulatory complications	0.000	0.982	0.017
E12.4 With neurological complications	0.000	0.982	0.017
E12.3 With ophthalmic complications	0.000	0.982	0.017
E12.2 With renal complications	0.000	0.982	0.017
E12.1 With ketoacidosis	0.000	0.982	0.017
E12.0 With coma	0.000	0.982	0.017
E13 Other specified diabetes mellitus	0.000	0.982	0.017
K25.5 Chronic or unspecified with perforation	0.017	0.983	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.016	0.984	0.000
K25.2 Acute with both haemorrhage and perforation	0.016	0.984	0.000
K25.1 Acute with perforation	0.016	0.984	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.016	0.984	0.000
K25.3 Acute without haemorrhage or perforation	0.016	0.984	0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.015	0.985	0.000
H35.4 Peripheral retinal degeneration	0.000	0.985	0.015
H35.2 Other proliferative retinopathy	0.000	0.985	0.015
H35 Other retinal disorders	0.000	0.986	0.014
H35.6 Retinal haemorrhage	0.000	0.987	0.013
E13.8 With unspecified complications	0.000	0.987	0.013
E13.7 With multiple complications	0.000	0.987	0.013
E13.6 With other specified complications	0.000	0.987	0.013
E13.5 With peripheral circulatory complications	0.000	0.987	0.013
E13.4 With neurological complications	0.000	0.987	0.013
E13.2 With renal complications	0.000	0.987	0.013
E13.1 With ketoacidosis	0.000	0.987	0.013
E13.0 With coma	0.000	0.987	0.013
E13.3 With ophthalmic complications	0.000	0.987	0.012
H35.5 Hereditary retinal dystrophy	0.000	0.987	0.013
E11.5 With peripheral circulatory complications	0.000	0.988	0.012
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.011	0.988	0.001
H35.7 Separation of retinal layers	0.000	0.988	0.012
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.011	0.989	0.000
K25.0 Acute with haemorrhage	0.010	0.989	0.000
S83.2 Tear of meniscus, current	0.000	0.990	0.010
K25.7 Chronic without haemorrhage or perforation	0.010	0.990	0.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.990	0.010
H35.1 Retinopathy of prematurity	0.000	0.990	0.010
E10.3 With ophthalmic complications	0.000	0.991	0.009
H35.0 Background retinopathy and retinal vascular changes	0.000	0.991	0.009
E11.1 With ketoacidosis	0.000	0.992	0.008
J31.1 Chronic nasopharyngitis	0.008	0.992	0.000
H35.9 Retinal disorder, unspecified	0.000	0.992	0.008
J31.2 Chronic pharyngitis	0.007	0.992	0.000
E11.7 With multiple complications	0.000	0.992	0.007
E11.8 With unspecified complications	0.000	0.993	0.007
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.993	0.007
I49.3 Ventricular premature depolarisation	0.007	0.993	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.993	0.007
K29 Gastritis and duodenitis	0.007	0.993	0.000
R01.1 Cardiac murmur, unspecified	0.000	0.994	0.006
K25.4 Chronic or unspecified with haemorrhage	0.006	0.994	0.000
H35.8 Other specified retinal disorders	0.000	0.994	0.006
E13.9 Without complications	0.000	0.994	0.006
E11.0 With coma	0.000	0.994	0.006
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.994	0.006
K29.2 Alcoholic gastritis	0.006	0.994	0.000
E11.3 With ophthalmic complications	0.000	0.994	0.006
S83.7 Injury to multiple structures of knee	0.000	0.994	0.006
K29.4 Chronic atrophic gastritis	0.006	0.994	0.000
S83.3 Tear of articular cartilage of knee, current	0.000	0.994	0.006
S83.0 Dislocation of patella	0.000	0.994	0.005
S83.1 Dislocation of knee	0.000	0.994	0.005
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.995	0.005
K29.3 Chronic superficial gastritis	0.005	0.995	0.000
K29.9 Gastroduodenitis, unspecified	0.005	0.995	0.000
E11.4 With neurological complications	0.000	0.995	0.005
K29.8 Duodenitis	0.005	0.995	0.000
A04.8 Other specified bacterial intestinal infections	0.005	0.995	0.000
O16 Unspecified maternal hypertension	0.000	0.995	0.005
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.996	0.004
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.004	0.996	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.996	0.004
M24.02 Loose body in joint (Upper arm)	0.000	0.996	0.004
M89.8 Other specified disorders of bone	0.000	0.996	0.004
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.996	0.004
M75.2 Bicipital tendinitis	0.000	0.996	0.004
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.004	0.996	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.004	0.996	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.996	0.004
S70.8 Other superficial injuries of hip and thigh	0.000	0.996	0.004
N48.6 Balanitis xerotica obliterans	0.004	0.996	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.004	0.996	0.000
S70.0 Contusion of hip	0.000	0.996	0.004
D68.8 Other specified coagulation defects	0.000	0.996	0.004
K29.0 Acute haemorrhagic gastritis	0.000	0.996	0.003
S82.60 Fracture of lateral malleolus (closed)	0.000	0.996	0.004
M89.81 Other specified disorders of bone (Shoulder region)	0.000	0.996	0.003
S70 Superficial injury of hip and thigh	0.000	0.996	0.004
M24.0 Loose body in joint	0.000	0.997	0.003
O47.9 False labour, unspecified	0.000	0.997	0.003
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.997	0.003
E11.6 With other specified complications	0.001	0.997	0.003
X62.9 Unspecified place	0.000	0.997	0.003
M24.07 Loose body in joint (Ankle and foot)	0.000	0.997	0.003
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.997	0.003
M00.9 Pyogenic arthritis, unspecified	0.000	0.997	0.003
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.997	0.003
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.997	0.003
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.003	0.997	0.000
M66.2 Spontaneous rupture of extensor tendons	0.003	0.997	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.000	0.997	0.003
L73.2 Hidradenitis suppurativa	0.003	0.997	0.000
M24.01 Loose body in joint (Shoulder region)	0.000	0.997	0.003
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.997	0.003
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.997	0.003
S70.1 Contusion of thigh	0.000	0.997	0.003
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.000	0.997	0.003
L50.8 Other urticaria	0.003	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.997	0.003
M89.89 Other specified disorders of bone (Site unspecified)	0.000	0.997	0.003
M89.82 Other specified disorders of bone (Upper arm)	0.000	0.997	0.003
M89.80 Other specified disorders of bone (Multiple sites)	0.000	0.997	0.003
M86.9 Osteomyelitis, unspecified	0.000	0.997	0.003
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
L52 Erythema nodosum	0.003	0.997	0.000
M89.88 Other specified disorders of bone (Other)	0.000	0.997	0.003
I10-I15 Hypertensive diseases	0.003	0.997	0.000
M24.06 Loose body in joint-Lower leg	0.000	0.997	0.003
M24.04 Loose body in joint (Hand)	0.000	0.997	0.003
M24.03 Loose body in joint (Forearm)	0.000	0.997	0.003
M89.83 Other specified disorders of bone (Forearm)	0.000	0.997	0.003
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.997	0.003
M89.84 Other specified disorders of bone (Hand)	0.000	0.997	0.003
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.000	0.997	0.003
L50.9 Urticaria, unspecified	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.997	0.003
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.997	0.003
L89.1 Stage II decubitus ulcer	0.000	0.997	0.003
E11.2 With renal complications	0.000	0.997	0.003
I87.1 Compression of vein	0.000	0.997	0.003
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.003	0.997	0.000
M24.09 Loose body in joint (Site unspecified)	0.000	0.997	0.003
M24.08 Loose body in joint (Other)	0.000	0.997	0.003
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.997	0.003
M24.00 Loose body in joint (Multiple sites)	0.000	0.997	0.003
L50 Urticaria	0.003	0.997	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.000	0.997	0.003
S70.7 Multiple superficial injuries of hip and thigh	0.000	0.997	0.003
M89 Other disorders of bone	0.000	0.997	0.003
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.000	0.997	0.003
M00.98 Pyogenic arthritis, unspecified (Other)	0.000	0.997	0.003
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.000	0.997	0.003
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.997	0.003
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.997	0.003
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.997	0.003
K83.1 Obstruction of bile duct	0.003	0.997	0.000
L51.1 Bullous erythema multiforme	0.003	0.997	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.997	0.003
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.997	0.003
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.997	0.003
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.997	0.003
L51 Erythema multiforme	0.003	0.997	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.002	0.997	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.002	0.997	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.002	0.997	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.002	0.997	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.002	0.997	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.002	0.997	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.002	0.997	0.000
M84.03 Malunion of fracture (Forearm)	0.000	0.997	0.003
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.003	0.997	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.000	0.997	0.002
I15 Secondary hypertension	0.003	0.997	0.000
K29.1 Other acute gastritis	0.003	0.997	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.997	0.002
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.997	0.002
M86.93 Osteomyelitis, unspecified (Forearm)	0.000	0.998	0.002
M86.92 Osteomyelitis, unspecified (Upper arm)	0.000	0.998	0.002
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.000	0.998	0.002
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.000	0.998	0.002
D13.2 Duodenum	0.002	0.998	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.002	0.998	0.000
M89.3 Hypertrophy of bone	0.000	0.998	0.002
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.998	0.002
Y83.5 Amputation of limb(s)	0.000	0.998	0.002
I13 Hypertensive heart and renal disease	0.002	0.998	0.000
L50-L54 Urticaria and erythema	0.002	0.998	0.000
I15.1 Hypertension secondary to other renal disorders	0.002	0.998	0.000
L51.9 Erythema multiforme, unspecified	0.002	0.998	0.000
G25.3 Myoclonus	0.000	0.998	0.002
M84.06 Malunion of fracture (Lower leg)	0.000	0.998	0.002
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.998	0.002
M87.9 Osteonecrosis, unspecified	0.000	0.998	0.002
M89.4 Other hypertrophic osteo-arthropathy	0.000	0.998	0.002
R41.3 Other amnesia	0.002	0.998	0.000
F05.9 Delirium, unspecified	0.000	0.998	0.002
F06.7 Mild cognitive disorder	0.000	0.998	0.002
M84.0 Malunion of fracture	0.000	0.998	0.002
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.000	0.998	0.002
I15.0 Renovascular hypertension	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.998	0.002
M86 Osteomyelitis	0.000	0.998	0.002
L50.6 Contact urticaria	0.002	0.998	0.000
L50.5 Cholinergic urticaria	0.002	0.998	0.000
L50.4 Vibratory urticaria	0.002	0.998	0.000
L50.3 Dermatographic urticaria	0.002	0.998	0.000
L50.2 Urticaria due to cold and heat	0.002	0.998	0.000
M87 Osteonecrosis	0.000	0.998	0.002
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.998	0.002
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.998	0.002
M89.6 Osteopathy after poliomyelitis	0.000	0.998	0.002
M89.2 Other disorders of bone development and growth	0.000	0.998	0.002
M89.1 Epiphyseal arrest	0.000	0.998	0.002
S62.3 Fracture of other metacarpal bone	0.000	0.998	0.002
R01 Cardiac murmurs and other cardiac sounds	0.000	0.998	0.002
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.998	0.002
L51.8 Other erythema multiforme	0.002	0.998	0.000
L51.2 Toxic epidermal necrolysis [Lyell]	0.002	0.998	0.000
L51.0 Nonbullous erythema multiforme	0.002	0.998	0.000
N30.2 Other chronic cystitis	0.002	0.998	0.000
A04 Other bacterial intestinal infections	0.002	0.998	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.998	0.002
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.000	0.998	0.002
M89.38 Hypertrophy of bone (Other)	0.000	0.998	0.002
M89.37 Hypertrophy of bone (Ankle and foot)	0.000	0.998	0.002
I15.8 Other secondary hypertension	0.002	0.998	0.000
I15.2 Hypertension secondary to endocrine disorders	0.002	0.998	0.000
M86-M90 Other osteopathies	0.000	0.998	0.002
M84.04 Malunion of fracture (Hand)	0.000	0.998	0.002
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.000	0.998	0.002
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.000	0.998	0.002
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.998	0.002
G25.2 Other specified forms of tremor	0.000	0.998	0.002
T79.3 Post-traumatic wound infection, not elsewhere classified	0.002	0.998	0.000
S62.31 Fracture of other metacarpal bone (open)	0.000	0.998	0.002
K63.9 Disease of intestine, unspecified	0.000	0.998	0.002
M89.5 Osteolysis	0.000	0.998	0.002
Z12.8 Special screening examination for neoplasm of other sites	0.000	0.998	0.002
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.998	0.002
M89.39 Hypertrophy of bone (Site unspecified)	0.000	0.998	0.002
M89.36 Hypertrophy of bone (Lower leg)	0.000	0.998	0.002
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.000	0.998	0.002
M89.34 Hypertrophy of bone (Hand)	0.000	0.998	0.002
M89.33 Hypertrophy of bone (Forearm)	0.000	0.998	0.002
M89.32 Hypertrophy of bone (Upper arm)	0.000	0.998	0.002
M89.31 Hypertrophy of bone (Shoulder region)	0.000	0.998	0.002
M89.30 Hypertrophy of bone (Multiple sites)	0.000	0.998	0.002
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.002	0.998	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.002	0.998	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
L54 Erythema in diseases classified elsewhere	0.002	0.998	0.000
A04.4 Other intestinal Escherichia coli infections	0.002	0.998	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.002	0.998	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.000	0.998	0.002
M87.96 Osteonecrosis, unspecified (Lower leg)	0.000	0.998	0.002
M87.94 Osteonecrosis, unspecified (Hand)	0.000	0.998	0.002
M87.93 Osteonecrosis, unspecified (Forearm)	0.000	0.998	0.002
M87.92 Osteonecrosis, unspecified (Upper arm)	0.000	0.998	0.002
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.000	0.998	0.002
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.000	0.998	0.002
M89.48 Other hypertrophic osteoarthropathy (Other)	0.000	0.998	0.002
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.000	0.998	0.002
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.000	0.998	0.002
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.000	0.998	0.002
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.000	0.998	0.002
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.000	0.998	0.002
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.000	0.998	0.002
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.000	0.998	0.002
M87.2 Osteonecrosis due to previous trauma	0.000	0.998	0.002
Z29.2 Other prophylactic chemotherapy	0.000	0.998	0.002
M84.09 Malunion of fracture (Site unspecified)	0.000	0.998	0.002
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.998	0.002
M84.01 Malunion of fracture (Shoulder region)	0.000	0.998	0.002
M84.00 Malunion of fracture (Multiple sites)	0.000	0.998	0.002
A04.9 Bacterial intestinal infection, unspecified	0.002	0.998	0.000
M87.8 Other osteonecrosis	0.000	0.998	0.002
M84.02 Malunion of fracture (Upper arm)	0.000	0.998	0.002
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.000	0.998	0.002
L50.1 Idiopathic urticaria	0.002	0.998	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.000	0.998	0.002
M89.9 Disorder of bone, unspecified	0.000	0.998	0.002
M86.5 Other chronic haematogenous osteomyelitis	0.000	0.998	0.002
M86.3 Chronic multifocal osteomyelitis	0.000	0.998	0.002
M86.2 Subacute osteomyelitis	0.000	0.998	0.002
M86.0 Acute haematogenous osteomyelitis	0.000	0.998	0.002
M87.3 Other secondary osteonecrosis	0.000	0.998	0.002
M87.0 Idiopathic aseptic necrosis of bone	0.000	0.998	0.002
X62.8 Other specified place	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
R09.2 Respiratory arrest	0.000	0.998	0.002
M00 Pyogenic arthritis	0.000	0.998	0.002
M66 Spontaneous rupture of synovium and tendon	0.002	0.998	0.000
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.002	0.998	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.000	0.998	0.002
M89.18 Epiphyseal arrest (Other)	0.000	0.998	0.002
M89.17 Epiphyseal arrest (Ankle and foot)	0.000	0.998	0.002
M89.16 Epiphyseal arrest (Lower leg)	0.000	0.998	0.002
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.000	0.998	0.002
M89.14 Epiphyseal arrest (Hand)	0.000	0.998	0.002
M89.13 Epiphyseal arrest (Forearm)	0.000	0.998	0.002
M89.12 Epiphyseal arrest (Upper arm)	0.000	0.998	0.002
M89.11 Epiphyseal arrest (Shoulder region)	0.000	0.998	0.002
M89.10 Epiphyseal arrest (Multiple sites)	0.000	0.998	0.002
M89.29 Other disorders of bone development and growth (Site unspecified)	0.000	0.998	0.002
M89.28 Other disorders of bone development and growth (Other)	0.000	0.998	0.002
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.000	0.998	0.002
M89.26 Other disorders of bone development and growth (Lower leg)	0.000	0.998	0.002
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.000	0.998	0.002
M89.24 Other disorders of bone development and growth (Hand)	0.000	0.998	0.002
M89.23 Other disorders of bone development and growth (Forearm)	0.000	0.998	0.002
M89.22 Other disorders of bone development and growth (Upper arm)	0.000	0.998	0.002
M89.21 Other disorders of bone development and growth (Shoulder region)	0.000	0.998	0.002
M89.20 Other disorders of bone development and growth (Multiple sites)	0.000	0.998	0.002
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.000	0.998	0.002
M89.68 Osteopathy after poliomyelitis (Other)	0.000	0.998	0.002
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.000	0.998	0.002
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.000	0.998	0.002
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.000	0.998	0.002
M89.64 Osteopathy after poliomyelitis (Hand)	0.000	0.998	0.002
M89.63 Osteopathy after poliomyelitis (Forearm)	0.000	0.998	0.002
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.000	0.998	0.002
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.000	0.998	0.002
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.000	0.998	0.002
J98.0 Diseases of bronchus, not elsewhere classified	0.002	0.998	0.000
M66.4 Spontaneous rupture of other tendons	0.002	0.998	0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.998	0.002
M87.1 Osteonecrosis due to drugs	0.000	0.998	0.002
S82.6 Fracture of lateral malleolus	0.000	0.998	0.002
Z57.2 Occupational exposure to dust	0.002	0.998	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.000	0.998	0.002
I63.8 Other cerebral infarction	0.002	0.998	0.000
R01.2 Other cardiac sounds	0.000	0.998	0.002
M84.08 Malunion of fracture (Other)	0.000	0.998	0.002
S52.20 Fracture of shaft of ulna (closed)	0.000	0.998	0.002
A02.0 Salmonella gastro-enteritis	0.002	0.998	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.002	0.998	0.000
A04.3 Enterohaemorrhagic Escherichia coli infection	0.002	0.998	0.000
A04.2 Enteroinvasive Escherichia coli infection	0.002	0.998	0.000
A04.1 Enterotoxigenic Escherichia coli infection	0.002	0.998	0.000
A04.0 Enteropathogenic Escherichia coli infection	0.002	0.998	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.002	0.998	0.000
X62.0 Home	0.000	0.998	0.002
X62.7 Farm	0.000	0.998	0.002
X62.6 Industrial and construction area	0.000	0.998	0.002
X62.5 Trade and service area	0.000	0.998	0.002
X62.4 Street and highway	0.000	0.998	0.002
X62.3 Sports and athletics area	0.000	0.998	0.002
X62.2 School, other institution and public administrative area	0.000	0.998	0.002
X62.1 Residential institution	0.000	0.998	0.002
M86.1 Other acute osteomyelitis	0.000	0.998	0.002
N39.9 Disorder of urinary system, unspecified	0.002	0.998	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.998	0.002
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.998	0.002
L50.0 Allergic urticaria	0.002	0.998	0.000
V44.5 Driver injured in traffic accident	0.002	0.998	0.000
M84 Disorders of continuity of bone	0.000	0.998	0.002
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.000	0.998	0.002
M89.59 Osteolysis (Site unspecified)	0.000	0.998	0.002
M89.58 Osteolysis (Other)	0.000	0.998	0.002
M89.57 Osteolysis (Ankle and foot)	0.000	0.998	0.002
M89.56 Osteolysis (Lower leg)	0.000	0.998	0.002
M89.54 Osteolysis (Hand)	0.000	0.998	0.002
M89.53 Osteolysis (Forearm)	0.000	0.998	0.002
M89.52 Osteolysis (Upper arm)	0.000	0.998	0.002
M89.51 Osteolysis (Shoulder region)	0.000	0.998	0.002
M89.50 Osteolysis (Multiple sites)	0.000	0.998	0.002
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.998	0.002
F32.0 Mild depressive episode	0.000	0.998	0.002
M86.6 Other chronic osteomyelitis	0.000	0.998	0.002
I31.3 Pericardial effusion (noninflammatory)	0.002	0.998	0.000
L54.8 Erythema in other diseases classified elsewhere	0.001	0.998	0.000
L54.0 Erythema marginatum in acute rheumatic fever	0.001	0.998	0.000
Z04.1 Examination and observation following transport accident	0.002	0.998	0.000
M88 Paget's disease of bone [osteitis deformans]	0.000	0.998	0.002
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.002	0.998	0.000
S22.40 Multiple fractures of ribs (closed)	0.002	0.998	0.000
D04.3 Skin of other and unspecified parts of face	0.000	0.998	0.002
I15.9 Seconday hypertension, unspecified	0.001	0.998	0.000
K31.7 Polyp of stomach and duodenum	0.002	0.998	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.998	0.002
M84.48 Pathological fracture, not elsewhere classified (Other)	0.001	0.998	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.000	0.998	0.002
G25.0 Essential tremor	0.000	0.998	0.002
G83.4 Cauda equina syndrome	0.000	0.998	0.002
M89.0 Algoneurodystrophy	0.000	0.998	0.002
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.998	0.001
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.000	0.998	0.001
M87.28 Osteonecrosis due to previous trauma (Other)	0.000	0.998	0.001
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.000	0.998	0.001
M87.24 Osteonecrosis due to previous trauma (Hand)	0.000	0.998	0.001
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.000	0.998	0.001
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.000	0.998	0.001
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.000	0.998	0.001
M87.89 Other osteonecrosis (Site unspecified)	0.000	0.998	0.001
M87.88 Other osteonecrosis (Other)	0.000	0.998	0.001
M87.87 Other osteonecrosis (Ankle and foot)	0.000	0.998	0.001
M87.86 Other osteonecrosis (Lower leg)	0.000	0.998	0.001
M87.84 Other osteonecrosis (Hand)	0.000	0.998	0.001
M87.83 Other osteonecrosis (Forearm)	0.000	0.998	0.001
M87.82 Other osteonecrosis (Upper arm)	0.000	0.998	0.001
M87.81 Other osteonecrosis (Shoulder region)	0.000	0.998	0.001
M87.80 Other osteonecrosis (Multiple sites)	0.000	0.998	0.001
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.998	0.002
K85.9 Acute pancreatitis, unspecified	0.000	0.998	0.002
M86.09 Acute haematogenous osteomyelitis (Site unspecified)	0.000	0.998	0.001
M86.08 Acute haematogenous osteomyelitis (Other)	0.000	0.998	0.001
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)	0.000	0.998	0.001
M86.06 Acute haematogenous osteomyelitis (Lower leg)	0.000	0.998	0.001
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)	0.000	0.998	0.001
M86.04 Acute haematogenous osteomyelitis (Hand)	0.000	0.998	0.001
M86.03 Acute haematogenous osteomyelitis (Forearm)	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations