TreeWAS – Variant ID: rs2458413

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K56.5 Intestinal adhesions [bands] with obstruction	0.000	0.963	0.037
Z42.0 Follow-up care involving plastic surgery of head and neck	0.019	0.981	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.015	0.985	0.000
M17.3 Other posttraumatic gonarthrosis	0.000	0.986	0.014
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.012	0.988	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.989	0.011
T36-T50 Poisoning by drugs, medicaments and biological substances	0.011	0.989	0.000
T43.2 Other and unspecified antidepressants	0.011	0.989	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.011	0.989	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.010	0.990	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.010	0.990	0.000
T36 Poisoning by systemic antibiotics	0.010	0.990	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.010	0.990	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.010	0.990	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.009	0.991	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.009	0.991	0.000
T43.9 Psychotropic drug, unspecified	0.009	0.991	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.009	0.991	0.000
T40.2 Other opioids	0.009	0.991	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.008	0.991	0.000
K22.2 Oesophageal obstruction	0.000	0.991	0.009
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.009	0.991	0.000
T36.3 Macrolides	0.008	0.992	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.008	0.992	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.008	0.992	0.000
T46.1 Calcium-channel blockers	0.008	0.992	0.000
T50.8 Diagnostic agents	0.008	0.992	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.008	0.992	0.000
T36.4 Tetracyclines	0.008	0.992	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.008	0.992	0.000
T43.6 Psychostimulants with abuse potential	0.008	0.992	0.000
T36.0 Penicillins	0.008	0.992	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.008	0.992	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.008	0.992	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.008	0.992	0.000
T46.7 Peripheral vasodilators	0.008	0.992	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.000	0.992	0.008
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.008	0.992	0.000
T50.4 Drugs affecting uric acid metabolism	0.008	0.992	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.008	0.992	0.000
T36.8 Other systemic antibiotics	0.007	0.992	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.007	0.992	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.007	0.992	0.000
T50.7 Analeptics and opioid receptor antagonists	0.007	0.993	0.000
T50.5 Appetite depressants	0.007	0.993	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.007	0.993	0.000
T50.1 Loop [high-ceiling] diuretics	0.007	0.993	0.000
T50.0 Mineralocorticoids and their antagonists	0.007	0.993	0.000
L89 Decubitus ulcer	0.007	0.993	0.000
L89.1 Stage II decubitus ulcer	0.007	0.993	0.000
T36.9 Systemic antibiotic, unspecified	0.007	0.993	0.000
T36.7 Antifungal antibiotics, systemically used	0.007	0.993	0.000
T36.6 Rifamycins	0.007	0.993	0.000
T36.5 Aminoglycosides	0.007	0.993	0.000
T36.2 Chloramphenicol group	0.007	0.993	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.007	0.993	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.007	0.993	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.007	0.993	0.000
L89.2 Stage III decubitus ulcer	0.007	0.993	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.007	0.993	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.007	0.993	0.000
T40.5 Cocaine	0.007	0.993	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.007	0.993	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.007	0.993	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.007	0.993	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.007	0.993	0.000
T38.5 Other oestrogens and progestogens	0.006	0.993	0.000
T38.0 Glucocorticoids and synthetic analogues	0.006	0.993	0.000
T38.1 Thyroid hormones and substitutes	0.006	0.993	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.006	0.994	0.000
T40.8 Lysergide [LSD]	0.006	0.994	0.000
T40.7 Cannabis (derivatives)	0.006	0.994	0.000
T40.3 Methadone	0.006	0.994	0.000
T40.0 Opium	0.006	0.994	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.006	0.994	0.000
T38.9 Other and unspecified hormone antagonists	0.006	0.994	0.000
T38.7 Androgens and anabolic congeners	0.006	0.994	0.000
T38.4 Oral contraceptives	0.006	0.994	0.000
T38.2 Antithyroid drugs	0.006	0.994	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.006	0.994	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.006	0.994	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.006	0.994	0.000
T49.9 Topical agent, unspecified	0.006	0.994	0.000
T49.8 Other topical agents	0.006	0.994	0.000
T49.7 Dental drugs, topically applied	0.006	0.994	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.006	0.994	0.000
T49.5 Ophthalmological drugs and preparations	0.006	0.994	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.006	0.994	0.000
T49.3 Emollients, demulcents and protectants	0.006	0.994	0.000
T49.2 Local astringents and local detergents	0.006	0.994	0.000
T49.1 Antipruritics	0.006	0.994	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.006	0.994	0.000
L89.3 Stage IV decubitus ulcer	0.006	0.994	0.000
T40.1 Heroin	0.006	0.994	0.000
T48.5 Anti-common-cold drugs	0.006	0.994	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.006	0.994	0.000
T48.4 Expectorants	0.006	0.994	0.000
T48.3 Antitussives	0.006	0.994	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.006	0.994	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.006	0.994	0.000
T48.0 Oxytocic drugs	0.006	0.994	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.006	0.994	0.000
T41.5 Therapeutic gases	0.006	0.994	0.000
T41.4 Anaesthetic, unspecified	0.006	0.994	0.000
T41.3 Local anaesthetics	0.006	0.994	0.000
T41.2 Other and unspecified general anaesthetics	0.006	0.994	0.000
T41.1 Intravenous anaesthetics	0.006	0.994	0.000
T41.0 Inhaled anaesthetics	0.006	0.994	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.006	0.994	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.006	0.994	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.006	0.994	0.000
T42.2 Succinimides and oxazolidinediones	0.006	0.994	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.005	0.994	0.000
T37.5 Antiviral drugs	0.005	0.994	0.000
T37.4 Anthelminthics	0.005	0.994	0.000
T37.3 Other antiprotozoal drugs	0.005	0.994	0.000
T37.1 Antimycobacterial drugs	0.005	0.994	0.000
T37.0 Sulphonamides	0.005	0.994	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.994	0.006
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.006	0.994	0.000
T42.0 Hydantoin derivatives	0.006	0.994	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.005	0.995	0.000
T45.8 Other primarily systemic and haematological agents	0.005	0.995	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.005	0.995	0.000
T45.6 Fibrinolysis-affecting drugs	0.005	0.995	0.000
T45.4 Iron and its compounds	0.005	0.995	0.000
T45.3 Enzymes, not elsewhere classified	0.005	0.995	0.000
T42.3 Barbiturates	0.005	0.995	0.000
T45.0 Antiallergic and antiemetic drugs	0.005	0.995	0.000
T47.0 Histamine H(2)-receptor antagonists	0.005	0.995	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
T47.7 Emetics	0.005	0.995	0.000
T47.5 Digestants	0.005	0.995	0.000
T47.3 Saline and osmotic laxatives	0.005	0.995	0.000
T47.2 Stimulant laxatives	0.005	0.995	0.000
T45.2 Vitamins, not elsewhere classified	0.005	0.995	0.000
Z42 Follow-up care involving plastic surgery	0.005	0.995	0.000
M66.0 Rupture of popliteal cyst	0.000	0.995	0.005
T40.6 Other and unspecified narcotics	0.005	0.995	0.000
T47.6 Antidiarrhoeal drugs	0.005	0.995	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.995	0.005
T39.0 Salicylates	0.005	0.995	0.000
T42.1 Iminostilbenes	0.005	0.995	0.000
I31.9 Disease of pericardium, unspecified	0.000	0.995	0.005
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.005	0.995	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.005	0.995	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.005	0.995	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.005	0.995	0.000
H33.3 Retinal breaks without detachment	0.005	0.995	0.000
Q66.8 Other congenital deformities of feet	0.005	0.995	0.000
T47.4 Other laxatives	0.004	0.995	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.996	0.004
T43.0 Tricyclic and tetracyclic antidepressants	0.004	0.996	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.004	0.996	0.000
Z42.9 Follow-up care involving plastic surgery, unspecified	0.004	0.996	0.000
E21.3 Hyperparathyroidism, unspecified	0.004	0.996	0.000
T45.5 Anticoagulants	0.004	0.996	0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.004	0.996	0.000
C09.9 Tonsil, unspecified	0.004	0.996	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.996	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.996	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.004	0.996	0.000
T44.0 Anticholinesterase agents	0.004	0.996	0.000
I20.1 Angina pectoris with documented spasm	0.000	0.996	0.004
M66.09 Rupture of popliteal cyst-Site unspec	0.000	0.996	0.004
M66.08 Rupture of popliteal cyst-Other	0.000	0.996	0.004
M66.07 Rupture of popliteal cyst-Ankle/foot	0.000	0.996	0.004
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.000	0.996	0.004
M66.04 Rupture of popliteal cyst-Hand	0.000	0.996	0.004
M66.03 Rupture of popliteal cyst-Forearm	0.000	0.996	0.004
M66.02 Rupture of popliteal cyst-Upper arm	0.000	0.996	0.004
M66.01 Rupture of popliteal cyst-Shldr region	0.000	0.996	0.004
M66.00 Rupture of popliteal cyst-Mult sites	0.000	0.996	0.004
Z93.2 Ileostomy status	0.000	0.996	0.004
T88.5 Other complications of anaesthesia	0.000	0.996	0.004
I27.9 Pulmonary heart disease, unspecified	0.004	0.996	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.004	0.996	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.996	0.004
T39.4 Antirheumatics, not elsewhere classified	0.004	0.996	0.000
T39.2 Pyrazolone derivatives	0.004	0.996	0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.004	0.996	0.000
Q66 Congenital deformities of feet	0.004	0.996	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.996	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.004	0.996	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.996	0.000
M54.36 Sciatica (Lumbar region)	0.000	0.996	0.003
I30.9 Acute pericarditis, unspecified	0.003	0.997	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.003	0.997	0.000
M54.3 Sciatica	0.000	0.997	0.003
E21.5 Disorder of parathyroid gland, unspecified	0.003	0.997	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.003	0.997	0.000
Q66.7 Pes cavus	0.003	0.997	0.000
J00 Acute nasopharyngitis [common cold]	0.003	0.997	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.997	0.003
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
Q66.9 Congenital deformity of feet, unspecified	0.003	0.997	0.000
T42.4 Benzodiazepines	0.003	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.003	0.997	0.000
I27.8 Other specified pulmonary heart diseases	0.003	0.997	0.000
Q76.0 Spina bifida occulta	0.003	0.997	0.000
M66.2 Spontaneous rupture of extensor tendons	0.000	0.997	0.003
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.003	0.997	0.000
U51 Admission status on psychiatric patients	0.003	0.997	0.000
M66 Spontaneous rupture of synovium and tendon	0.000	0.997	0.003
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
U51.1 Previously admitted to a psychiatric hospital of the provider	0.003	0.997	0.000
E21.2 Other hyperparathyroidism	0.003	0.997	0.000
Q66.5 Congenital pes planus	0.003	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.003	0.997	0.000
Q66.1 Talipes calcaneovarus	0.003	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
Q66.2 Metatarsus varus	0.003	0.997	0.000
T40.4 Other synthetic narcotics	0.002	0.997	0.001
Q79.6 Ehlers-Danlos syndrome	0.003	0.997	0.000
S22.20 Fracture of sternum (closed)	0.003	0.997	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.000	0.997	0.003
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.000	0.997	0.003
Q66.6 Other congenital valgus deformities of feet	0.003	0.997	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.000	0.997	0.003
Q66.0 Talipes equinovarus	0.003	0.997	0.000
Q79.1 Other congenital malformations of diaphragm	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
Q66.3 Other congenital varus deformities of feet	0.003	0.997	0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
M54.35 Sciatica (Thoracolumbar region)	0.000	0.997	0.003
M54.34 Sciatica-Thoracic	0.000	0.997	0.003
M54.33 Sciatica-Cervicothoracic	0.000	0.997	0.003
M54.32 Sciatica-Cervical	0.000	0.997	0.003
M54.31 Sciatica-Occipit-atl-axl	0.000	0.997	0.003
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.997	0.003
E83.1 Disorders of iron metabolism	0.000	0.997	0.003
Q74.1 Congenital malformation of knee	0.003	0.997	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.000	0.997	0.002
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.997	0.003
M54.30 Sciatica (Multiple sites in spine)	0.000	0.997	0.002
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.000	0.997	0.002
M66.28 Spontaneous rupture of extensor tendons-Other	0.000	0.997	0.002
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.000	0.997	0.002
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.000	0.997	0.002
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.000	0.997	0.002
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.000	0.997	0.002
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.000	0.997	0.002
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.997	0.003
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.003	0.997	0.000
M54.37 Sciatica (Lumbosacral region)	0.000	0.998	0.002
Q79.0 Congenital diaphragmatic hernia	0.002	0.998	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.000	0.998	0.002
U51.2 Previously admitted to a psychiatric hospital of another provider	0.002	0.998	0.000
M66.1 Rupture of synovium	0.000	0.998	0.002
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.998	0.000
Q79.4 Prune belly syndrome	0.002	0.998	0.000
Q79.3 Gastroschisis	0.002	0.998	0.000
Q79.2 Exomphalos	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
E21.4 Other specified disorders of parathyroid gland	0.002	0.998	0.000
I27 Other pulmonary heart diseases	0.002	0.998	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.002
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
M66.3 Spontaneous rupture of flexor tendons	0.000	0.998	0.002
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.998	0.000
Q76.7 Congenital malformation of sternum	0.002	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.998	0.002
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
Q74.9 Unspecified congenital malformation of limb(s)	0.002	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.002	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.002	0.998	0.000
C09 Malignant neoplasm of tonsil	0.002	0.998	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.000	0.998	0.002
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.002	0.998	0.000
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.000	0.998	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
K12.1 Other forms of stomatitis	0.000	0.998	0.002
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
Q78.0 Osteogenesis imperfecta	0.002	0.998	0.000
D10.3 Other and unspecified parts of mouth	0.002	0.998	0.000
D10.1 Tongue	0.002	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.002	0.998	0.000
M66.4 Spontaneous rupture of other tendons	0.000	0.998	0.002
G82.4 Spastic tetraplegia	0.002	0.998	0.000
Q76.5 Cervical rib	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.000	0.998	0.002
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.000	0.998	0.002
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.000	0.998	0.002
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.000	0.998	0.002
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.000	0.998	0.002
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.000	0.998	0.002
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.000	0.998	0.002
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.000	0.998	0.002
S42.3 Fracture of shaft of humerus	0.000	0.998	0.002
M66.19 Rupture of synovium (Site unspecified)	0.000	0.998	0.002
M66.18 Rupture of synovium (Other)	0.000	0.998	0.002
M66.17 Rupture of synovium (Ankle and foot)	0.000	0.998	0.002
M66.16 Rupture of synovium (Lower leg)	0.000	0.998	0.002
M66.15 Rupture of synovium (Pelvic region and thigh)	0.000	0.998	0.002
M66.14 Rupture of synovium (Hand)	0.000	0.998	0.002
M66.13 Rupture of synovium (Forearm)	0.000	0.998	0.002
M66.12 Rupture of synovium (Upper arm)	0.000	0.998	0.002
M66.11 Rupture of synovium (Shoulder region)	0.000	0.998	0.002
M66.10 Rupture of synovium (Multiple sites)	0.000	0.998	0.002
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
Q69.9 Polydactyly, unspecified	0.002	0.998	0.000
Q69.2 Accessory toe(s)	0.002	0.998	0.000
Q69.1 Accessory thumb(s)	0.002	0.998	0.000
Q69.0 Accessory finger(s)	0.002	0.998	0.000
Q70.9 Syndactyly, unspecified	0.002	0.998	0.000
Q70.4 Polysyndactyly	0.002	0.998	0.000
Q70.3 Webbed toes	0.002	0.998	0.000
Q70.2 Fused toes	0.002	0.998	0.000
Q70.1 Webbed fingers	0.002	0.998	0.000
Q70.0 Fused fingers	0.002	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.998	0.000
Q71.6 Lobster-claw hand	0.002	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.002	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.002	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.002	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.002	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.002	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.002	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.002	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.002	0.998	0.000
Q72.7 Split foot	0.002	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.002	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.002	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.002	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.002	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.002	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.002	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.002	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.002	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.002	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.002	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.002	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.002	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.002	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.002	0.998	0.000
Q75.3 Macrocephaly	0.002	0.998	0.000
Q75.2 Hypertelorism	0.002	0.998	0.000
Q75.1 Craniofacial dysostosis	0.002	0.998	0.000
Q75.0 Craniosynostosis	0.002	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.998	0.000
Q77.5 Diastrophic dysplasia	0.002	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.998	0.000
Q77.2 Short rib syndrome	0.002	0.998	0.000
Q77.1 Thanatophoric short stature	0.002	0.998	0.000
Q77.0 Achondrogenesis	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
Q77.4 Achondroplasia	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.000	0.998	0.002
I27.1 Kyphoscoliotic heart disease	0.002	0.998	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
Q65.6 Unstable hip	0.002	0.998	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.998	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.998	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.998	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.998	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.998	0.000
Q68.3 Congenital bowing of femur	0.002	0.998	0.000
Q68.2 Congenital deformity of knee	0.002	0.998	0.000
Q68.1 Congenital deformity of hand	0.002	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.998	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.998	0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.000	0.998	0.002
M66.38 Spontaneous rupture of flexor tendons (Other)	0.000	0.998	0.002
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.000	0.998	0.002
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.000	0.998	0.002
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.000	0.998	0.002
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.000	0.998	0.002
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.000	0.998	0.002
M79.63 Pain in limb (Forearm)	0.000	0.998	0.002
Q65.9 Congenital deformity of hip, unspecified	0.002	0.998	0.000
Q78.2 Osteopetrosis	0.002	0.998	0.000
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.000	0.998	0.002
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.998	0.002
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.998	0.002
Q18.1 Preauricular sinus and cyst	0.000	0.998	0.002
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.002
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.000	0.998	0.002
C09.8 Overlapping lesion of tonsil	0.002	0.998	0.000
C09.0 Tonsillar fossa	0.002	0.998	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.000	0.998	0.002
T88.1 Other complications following immunisation, not elsewhere classified	0.000	0.998	0.002
T88.0 Infection following immunisation	0.000	0.998	0.002
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
I30 Acute pericarditis	0.002	0.998	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.998	0.002
C09.1 Tonsillar pillar (anterior) (posterior)	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
M76.86 Other enthesopathies of lower limb, excluding foot (Lower leg)	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.000	0.998	0.002
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.000	0.998	0.002
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.000	0.998	0.002
M66.48 Spontaneous rupture of other tendons (Other)	0.000	0.998	0.002
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.000	0.998	0.002
M66.44 Spontaneous rupture of other tendons (Hand)	0.000	0.998	0.002
M66.43 Spontaneous rupture of other tendons (Forearm)	0.000	0.998	0.002
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.000	0.998	0.002
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.000	0.998	0.002
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.002	0.998	0.000
M06.9 Rheumatoid arthritis, unspecified	0.000	0.998	0.002
S42.31 Fracture of shaft of humerus (open)	0.000	0.998	0.002
I45.3 Trifascicular block	0.002	0.998	0.000
D10.0 Lip	0.002	0.998	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.000	0.998	0.002
D10 Benign neoplasm of mouth and pharynx	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
Q67.6 Pectus excavatum	0.001	0.998	0.000
Z90.8 Acquired absence of other organs	0.000	0.998	0.002
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.998	0.001
F43.1 Posttraumatic stress disorder	0.002	0.998	0.000
I30.8 Other forms of acute pericarditis	0.002	0.998	0.000
T93.1 Sequelae of fracture of femur	0.000	0.998	0.002
I30.1 Infective pericarditis	0.002	0.998	0.000
L81.9 Disorder of pigmentation, unspecified	0.000	0.998	0.002
L95.8 Other vasculitis limited to skin	0.002	0.998	0.000
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.000	0.998	0.001
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
F23.9 Acute and transient psychotic disorder, unspecified	0.000	0.998	0.002
T88.2 Shock due to anaesthesia	0.000	0.998	0.001
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.998	0.001
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.998	0.001
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.001
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.001
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.001
K80.0 Calculus of gallbladder with acute cholecystitis	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.001	0.998	0.000
W44.0 Home	0.000	0.998	0.002
I30.0 Acute nonspecific idiopathic pericarditis	0.001	0.998	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.998	0.002
T88.9 Complication of surgical and medical care, unspecified	0.000	0.998	0.001
L29.0 Pruritus ani	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.998	0.002
F60.9 Personality disorder, unspecified	0.002	0.998	0.000
B15.9 Hepatitis A without hepatic coma	0.000	0.998	0.002
Q87.4 Marfan's syndrome	0.000	0.998	0.002
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.998	0.001
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.000	0.998	0.001
D10.7 Hypopharynx	0.001	0.998	0.000
D10.6 Nasopharynx	0.001	0.998	0.000
D10.2 Floor of mouth	0.001	0.998	0.000
L20.9 Atopic dermatitis, unspecified	0.000	0.998	0.001
F43.9 Reaction to severe stress, unspecified	0.001	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.000	0.998	0.001
T92.2 Sequelae of fracture at wrist and hand level	0.001	0.998	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.999	0.001
D10.9 Pharynx, unspecified	0.001	0.999	0.000
F80.1 Expressive language disorder	0.000	0.999	0.001
W19.3 Sports and athletics area	0.001	0.999	0.000
D10.4 Tonsil	0.001	0.999	0.000
I27.0 Primary pulmonary hypertension	0.001	0.999	0.000
D23.9 Skin, unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations