TreeWAS – Variant ID: rs2486152

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R47.0 Dysphasia and aphasia	0.020	0.980	0.000
R47 Speech disturbances, not elsewhere classified	0.013	0.987	0.000
R47.8 Other and unspecified speech disturbances	0.011	0.989	0.000
R47.1 Dysarthria and anarthria	0.010	0.990	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.991	0.009
C79 Secondary malignant neoplasm of other sites	0.000	0.991	0.009
C79.6 Secondary malignant neoplasm of ovary	0.000	0.992	0.008
C79.2 Secondary malignant neoplasm of skin	0.000	0.992	0.008
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.992	0.008
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.993	0.007
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.993	0.007
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.993	0.007
T42.4 Benzodiazepines	0.000	0.993	0.007
T42.1 Iminostilbenes	0.000	0.993	0.007
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.993	0.007
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.994	0.006
D23.4 Skin of scalp and neck	0.000	0.994	0.006
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.994	0.006
J33.0 Polyp of nasal cavity	0.005	0.995	0.000
T42.0 Hydantoin derivatives	0.000	0.995	0.005
O75 Other complications of labour and delivery, not elsewhere classified	0.005	0.995	0.000
O66 Other obstructed labour	0.005	0.995	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.995	0.005
T42.2 Succinimides and oxazolidinediones	0.000	0.995	0.005
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.995	0.005
O75.7 Vaginal delivery following previous Caesarean section	0.005	0.995	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.995	0.005
T42.3 Barbiturates	0.000	0.995	0.005
O66.0 Obstructed labour due to shoulder dystocia	0.005	0.995	0.000
O70.1 Second degree perineal laceration during delivery	0.005	0.995	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.005	0.995	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.995	0.005
N13 Obstructive and reflux uropathy	0.005	0.995	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.005	0.995	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.995	0.005
N13.5 Kinking and stricture of ureter without hydronephrosis	0.004	0.995	0.000
O60-O75 Complications of labour and delivery	0.004	0.996	0.000
O75.0 Maternal distress during labour and delivery	0.004	0.996	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.996	0.004
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.004	0.996	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.004	0.996	0.000
O66.2 Obstructed labour due to unusually large foetus	0.004	0.996	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.996	0.004
O75.5 Delayed delivery after artificial rupture of membranes	0.004	0.996	0.000
O66.4 Failed trial of labour, unspecified	0.004	0.996	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.004	0.996	0.000
D23.2 Skin of ear and external auricular canal	0.000	0.996	0.004
N13.6 Pyonephrosis	0.004	0.996	0.000
N13.8 Other obstructive and reflux uropathy	0.004	0.996	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.996	0.004
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.996	0.004
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.996	0.004
O66.9 Obstructed labour, unspecified	0.004	0.996	0.000
O66.8 Other specified obstructed labour	0.004	0.996	0.000
T40.4 Other synthetic narcotics	0.000	0.996	0.004
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.996	0.004
O64 Obstructed labour due to malposition and malpresentation of foetus	0.004	0.996	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.996	0.004
O64.1 Obstructed labour due to breech presentation	0.004	0.996	0.000
O75.4 Other complications of obstetric surgery and procedures	0.004	0.996	0.000
O75.1 Shock during or following labour and delivery	0.004	0.996	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.004	0.996	0.000
O75.8 Other specified complications of labour and delivery	0.004	0.996	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.004	0.996	0.000
O66.1 Obstructed labour due to locked twins	0.004	0.996	0.000
O75.9 Complication of labour and delivery, unspecified	0.004	0.996	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.996	0.004
N13.3 Other and unspecified hydronephrosis	0.004	0.996	0.000
F99 Mental disorder, not otherwise specified	0.000	0.996	0.004
O62 Abnormalities of forces of labour	0.004	0.996	0.000
O73 Retained placenta and membranes, without haemorrhage	0.004	0.996	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.996	0.004
S81.9 Open wound of lower leg, part unspecified	0.000	0.996	0.004
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.996	0.004
R47-R49 Symptoms and signs involving speech and voice	0.004	0.996	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.996	0.004
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.004	0.996	0.000
T47.2 Stimulant laxatives	0.000	0.996	0.004
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.996	0.004
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.996	0.003
O74 Complications of anaesthesia during labour and delivery	0.004	0.996	0.000
O71 Other obstetric trauma	0.004	0.996	0.000
O70 Perineal laceration during delivery	0.004	0.996	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.996	0.003
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.996	0.003
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.996	0.003
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.996	0.003
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.996	0.003
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.996	0.003
T44.0 Anticholinesterase agents	0.000	0.996	0.003
O62.1 Secondary uterine inertia	0.003	0.996	0.000
O75.3 Other infection during labour	0.003	0.996	0.000
T39.0 Salicylates	0.000	0.996	0.003
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.996	0.003
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.996	0.003
D23 Other benign neoplasms of skin	0.000	0.996	0.004
T40.6 Other and unspecified narcotics	0.000	0.997	0.003
T40.3 Methadone	0.000	0.997	0.003
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
O73.0 Retained placenta, without haemorrhage	0.003	0.997	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
N41 Inflammatory diseases of prostate	0.000	0.997	0.003
O60 Preterm delivery	0.003	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.997	0.003
T47.6 Antidiarrhoeal drugs	0.000	0.997	0.003
N13.7 Vesicoureteral-reflux-associated uropathy	0.003	0.997	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.997	0.003
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.997	0.003
O70.9 Perineal laceration during delivery, unspecified	0.003	0.997	0.000
M65.34 Trigger finger-Hand	0.000	0.997	0.003
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.997	0.003
N41.0 Acute prostatitis	0.000	0.997	0.003
T36 Poisoning by systemic antibiotics	0.000	0.997	0.003
T46.1 Calcium-channel blockers	0.000	0.997	0.003
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.997	0.003
T68 Hypothermia	0.000	0.997	0.003
T40.1 Heroin	0.000	0.997	0.003
O61 Failed induction of labour	0.003	0.997	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.997	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.997	0.003
O65 Obstructed labour due to maternal pelvic abnormality	0.003	0.997	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.003	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.000	0.997	0.003
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.003	0.997	0.000
O62.9 Abnormality of forces of labour, unspecified	0.003	0.997	0.000
O72 Postpartum haemorrhage	0.003	0.997	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.997	0.003
T40.8 Lysergide [LSD]	0.000	0.997	0.003
T40.7 Cannabis (derivatives)	0.000	0.997	0.003
T40.0 Opium	0.000	0.997	0.003
N13.4 Hydroureter	0.003	0.997	0.000
O64.3 Obstructed labour due to brow presentation	0.003	0.997	0.000
O71.7 Obstetric haematoma of pelvis	0.003	0.997	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.997	0.003
T46.7 Peripheral vasodilators	0.000	0.997	0.003
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.997	0.003
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.997	0.003
T47.7 Emetics	0.000	0.997	0.003
T47.5 Digestants	0.000	0.997	0.003
T47.3 Saline and osmotic laxatives	0.000	0.997	0.003
O68 Labour and delivery complicated by foetal stress [distress]	0.003	0.997	0.000
O64.5 Obstructed labour due to compound presentation	0.003	0.997	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.997	0.003
T47.0 Histamine H(2)-receptor antagonists	0.000	0.997	0.003
T50.8 Diagnostic agents	0.000	0.997	0.003
O62.8 Other abnormalities of forces of labour	0.003	0.997	0.000
O72.1 Other immediate postpartum haemorrhage	0.003	0.997	0.000
O64.4 Obstructed labour due to shoulder presentation	0.003	0.997	0.000
T50.7 Analeptics and opioid receptor antagonists	0.000	0.997	0.003
T50.5 Appetite depressants	0.000	0.997	0.003
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.997	0.003
T50.0 Mineralocorticoids and their antagonists	0.000	0.997	0.003
D23.9 Skin, unspecified	0.000	0.997	0.003
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.997	0.003
T47.4 Other laxatives	0.000	0.997	0.003
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.997	0.003
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.997	0.003
O71.6 Obstetric damage to pelvic joints and ligaments	0.003	0.997	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.997	0.003
T39.4 Antirheumatics, not elsewhere classified	0.000	0.997	0.003
T39.2 Pyrazolone derivatives	0.000	0.997	0.003
T40.5 Cocaine	0.000	0.997	0.003
D22.4 Melanocytic naevi of scalp and neck	0.003	0.997	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.997	0.003
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.003	0.997	0.000
N41.2 Abscess of prostate	0.000	0.997	0.003
O64.8 Obstructed labour due to other malposition and malpresentation	0.003	0.997	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.003	0.997	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.003	0.997	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.997	0.003
D23.5 Skin of trunk	0.000	0.997	0.003
C85.1 B-cell lymphoma, unspecified	0.000	0.997	0.003
O62.2 Other uterine inertia	0.003	0.997	0.000
D23.7 Skin of lower limb, including hip	0.000	0.997	0.003
O64.2 Obstructed labour due to face presentation	0.003	0.997	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.003	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.997	0.003
T48.4 Expectorants	0.000	0.997	0.003
T48.3 Antitussives	0.000	0.997	0.003
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.997	0.003
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.997	0.003
T48.0 Oxytocic drugs	0.000	0.997	0.003
T41.2 Other and unspecified general anaesthetics	0.000	0.997	0.003
O71.5 Other obstetric injury to pelvic organs	0.003	0.997	0.000
T41.5 Therapeutic gases	0.000	0.997	0.003
T41.4 Anaesthetic, unspecified	0.000	0.997	0.003
T41.3 Local anaesthetics	0.000	0.997	0.003
T41.1 Intravenous anaesthetics	0.000	0.997	0.003
T41.0 Inhaled anaesthetics	0.000	0.997	0.003
T48.5 Anti-common-cold drugs	0.000	0.997	0.003
O69 Labour and delivery complicated by umbilical cord complications	0.003	0.997	0.000
O61.1 Failed instrumental induction of labour	0.003	0.997	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.003	0.997	0.000
O71.2 Postpartum inversion of uterus	0.003	0.997	0.000
O71.1 Rupture of uterus during labour	0.003	0.997	0.000
O71.0 Rupture of uterus before onset of labour	0.003	0.997	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.003	0.997	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.003	0.997	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.003	0.997	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.003	0.997	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.003	0.997	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.003	0.997	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.003	0.997	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.003	0.997	0.000
D23.6 Skin of upper limb, including shoulder	0.000	0.997	0.003
T50.4 Drugs affecting uric acid metabolism	0.000	0.997	0.003
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.003	0.997	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.003	0.997	0.000
R60.9 Oedema, unspecified	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.997	0.003
N41.1 Chronic prostatitis	0.000	0.997	0.003
O62.3 Precipitate labour	0.003	0.997	0.000
O71.8 Other specified obstetric trauma	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.997	0.003
O71.9 Obstetric trauma, unspecified	0.003	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.997	0.003
T37.5 Antiviral drugs	0.000	0.997	0.003
T37.4 Anthelminthics	0.000	0.997	0.003
T37.3 Other antiprotozoal drugs	0.000	0.997	0.003
T37.1 Antimycobacterial drugs	0.000	0.997	0.003
T37.0 Sulphonamides	0.000	0.997	0.003
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.003	0.997	0.000
O71.3 Obstetric laceration of cervix	0.003	0.997	0.000
N41.3 Prostatocystitis	0.000	0.997	0.003
O60.3 Preterm delivery without spontaneous labour	0.003	0.997	0.000
O60.2 Preterm spontaneous labour with term delivery	0.003	0.997	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.003	0.997	0.000
O60.0 Preterm labour without delivery	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.000	0.997	0.002
T49.8 Other topical agents	0.000	0.997	0.002
T49.7 Dental drugs, topically applied	0.000	0.997	0.002
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.997	0.002
T49.5 Ophthalmological drugs and preparations	0.000	0.997	0.002
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.997	0.002
T49.3 Emollients, demulcents and protectants	0.000	0.997	0.002
T49.2 Local astringents and local detergents	0.000	0.997	0.002
T49.1 Antipruritics	0.000	0.997	0.002
T38.0 Glucocorticoids and synthetic analogues	0.000	0.997	0.003
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.997	0.002
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.997	0.003
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.997	0.002
O62.0 Primary inadequate contractions	0.002	0.997	0.000
O70.3 Fourth degree perineal laceration during delivery	0.002	0.997	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.997	0.002
T36.8 Other systemic antibiotics	0.000	0.997	0.002
T36.7 Antifungal antibiotics, systemically used	0.000	0.997	0.002
T36.6 Rifamycins	0.000	0.997	0.002
T36.5 Aminoglycosides	0.000	0.997	0.002
T36.2 Chloramphenicol group	0.000	0.997	0.002
N41.8 Other inflammatory diseases of prostate	0.000	0.997	0.002
O61.8 Other failed induction of labour	0.002	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.997	0.002
T38.7 Androgens and anabolic congeners	0.000	0.997	0.002
T38.5 Other oestrogens and progestogens	0.000	0.997	0.002
T38.4 Oral contraceptives	0.000	0.997	0.002
T38.2 Antithyroid drugs	0.000	0.997	0.002
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.002	0.997	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.002	0.997	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.002	0.997	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.002	0.997	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.002	0.997	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.002	0.997	0.000
O65.0 Obstructed labour due to deformed pelvis	0.002	0.997	0.000
T36.4 Tetracyclines	0.000	0.997	0.002
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.997	0.003
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.997	0.003
O71.4 Obstetric high vaginal laceration alone	0.002	0.997	0.000
O72.3 Postpartum coagulation defects	0.002	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.997	0.002
T36.0 Penicillins	0.000	0.997	0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.997	0.002
Z95.0 Presence of cardiac pacemaker	0.003	0.997	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.997	0.003
O67.8 Other intrapartum haemorrhage	0.002	0.997	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.997	0.002
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.997	0.002
N10-N16 Renal tubulo-interstitial diseases	0.003	0.997	0.000
C92.0 Acute myeloid leukaemia	0.000	0.997	0.002
D23.0 Skin of lip	0.000	0.997	0.002
T36.3 Macrolides	0.000	0.997	0.002
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.003	0.997	0.000
O61.9 Failed induction of labour, unspecified	0.002	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
O67.0 Intrapartum haemorrhage with coagulation defect	0.002	0.998	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.998	0.002
O47.9 False labour, unspecified	0.002	0.998	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.002	0.998	0.000
Y83.8 Other surgical procedures	0.002	0.998	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.998	0.002
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.002	0.998	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.002	0.998	0.000
O69.3 Labour and delivery complicated by short cord	0.002	0.998	0.000
Z86.5 Personal history of other mental and behavioural disorders	0.000	0.998	0.002
C92.9 Myeloid leukaemia, unspecified	0.000	0.998	0.002
R48.2 Apraxia	0.002	0.998	0.000
R48.1 Agnosia	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.002
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.002
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.002
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.002
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.002
T45.2 Vitamins, not elsewhere classified	0.000	0.998	0.002
C92 Myeloid leukaemia	0.000	0.998	0.002
N11 Chronic tubulo-interstitial nephritis	0.002	0.998	0.000
L85.8 Other specified epidermal thickening	0.002	0.998	0.000
R48.8 Other and unspecified symbolic dysfunctions	0.002	0.998	0.000
R94.5 Abnormal results of liver function studies	0.002	0.998	0.000
T45.4 Iron and its compounds	0.000	0.998	0.002
R48.0 Dyslexia and alexia	0.002	0.998	0.000
N11.1 Chronic obstructive pyelonephritis	0.002	0.998	0.000
O61.0 Failed medical induction of labour	0.002	0.998	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.002	0.998	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.002	0.998	0.000
L28.0 Lichen simplex chronicus	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
K61.3 Ischiorectal abscess	0.000	0.998	0.002
N99.4 Postprocedural pelvic peritoneal adhesions	0.002	0.998	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.002	0.998	0.000
H27.0 Aphakia	0.000	0.998	0.002
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.998	0.002
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.000	0.998	0.002
O69.8 Labour and delivery complicated by other cord complications	0.002	0.998	0.000
T51.0 Ethanol	0.000	0.998	0.002
Z04.9 Examination and observation for unspecified reason	0.000	0.998	0.002
R49 Voice disturbances	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.998	0.002
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
D23.3 Skin of other and unspecified parts of face	0.000	0.998	0.002
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.002	0.998	0.000
N99.2 Postprocedural adhesions of vagina	0.002	0.998	0.000
N04.9 Unspecified	0.002	0.998	0.000
O72.0 Third-stage haemorrhage	0.002	0.998	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.998	0.002
C92.7 Other myeloid leukaemia	0.000	0.998	0.002
C92.1 Chronic myeloid leukaemia	0.000	0.998	0.002
Z35.1 Supervision of pregnancy with history of abortive outcome	0.002	0.998	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.002	0.998	0.000
T39.1 4-Aminophenol derivatives	0.000	0.998	0.002
T45.5 Anticoagulants	0.000	0.998	0.002
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
L29.9 Pruritus, unspecified	0.002	0.998	0.000
C92.2 Subacute myeloid leukaemia	0.000	0.998	0.002
H65.2 Chronic serous otitis media	0.000	0.998	0.002
M11.2 Other chondrocalcinosis	0.000	0.998	0.002
O72.2 Delayed and secondary postpartum haemorrhage	0.002	0.998	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.002	0.998	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.002	0.998	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.998	0.002
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.998	0.002
C92.3 Myeloid sarcoma	0.000	0.998	0.002
M65.3 Trigger finger	0.000	0.998	0.002
R49.8 Other and unspecified voice disturbances	0.002	0.998	0.000
C90.0 Multiple myeloma	0.000	0.998	0.002
N11.8 Other chronic tubulo-interstitial nephritis	0.002	0.998	0.000
T40.2 Other opioids	0.000	0.998	0.002
S81 Open wound of lower leg	0.000	0.998	0.002
O67.9 Intrapartum haemorrhage, unspecified	0.002	0.998	0.000
S81.0 Open wound of knee	0.000	0.998	0.002
C92.5 Acute myelomonocytic leukaemia	0.000	0.998	0.002
N15 Other renal tubulo-interstitial diseases	0.002	0.998	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.000	0.998	0.002
S82.00 Fracture of patella (closed)	0.000	0.998	0.002
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.002
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.998	0.002
C92.4 Acute promyelocytic leukaemia	0.000	0.998	0.002
D38.1 Trachea, bronchus and lung	0.002	0.998	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.002	0.998	0.000
N10 Acute tubulo-interstitial nephritis	0.002	0.998	0.000
H17.9 Corneal scar and opacity, unspecified	0.000	0.998	0.002
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.002	0.998	0.000
O63 Long labour	0.002	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.998	0.002
Z92.4 Personal history of major surgery, not elsewhere classified	0.002	0.998	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.002	0.998	0.000
N14.3 Nephropathy induced by heavy metals	0.002	0.998	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.002	0.998	0.000
N14.0 Analgesic nephropathy	0.002	0.998	0.000
O70.2 Third degree perineal laceration during delivery	0.002	0.998	0.000
T51 Toxic effect of alcohol	0.000	0.998	0.002
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.998	0.002
O36.8 Maternal care for other specified foetal problems	0.002	0.998	0.000
R49.2 Hypernasality and hyponasality	0.002	0.998	0.000
Z12.4 Special screening examination for neoplasm of cervix	0.002	0.998	0.000
H65 Nonsuppurative otitis media	0.000	0.998	0.002
C85.0 Lymphosarcoma	0.000	0.998	0.002
M07.3 Other psoriatic arthropathies	0.000	0.998	0.002
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.002	0.998	0.000
F99-F99 Unspecified mental disorder	0.000	0.998	0.002
M11.21 Other chondrocalcinosis (Shoulder region)	0.000	0.998	0.002
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.998	0.002
I34.0 Mitral (valve) insufficiency	0.002	0.998	0.000
T51.9 Alcohol, unspecified	0.000	0.998	0.002
M11.29 Other chondrocalcinosis (Site unspecified)	0.000	0.998	0.002
M11.28 Other chondrocalcinosis (Other)	0.000	0.998	0.002
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.000	0.998	0.002
M11.24 Other chondrocalcinosis (Hand)	0.000	0.998	0.002
M11.22 Other chondrocalcinosis (Upper arm)	0.000	0.998	0.002
M11.20 Other chondrocalcinosis (Multiple sites)	0.000	0.998	0.002
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.998	0.002
N05.9 Unspecified	0.002	0.998	0.000
M65.38 Trigger finger-Other	0.000	0.998	0.001
M65.37 Trigger finger-Ankle/foot	0.000	0.998	0.001
M65.36 Trigger finger-Lower leg	0.000	0.998	0.001
M65.35 Trigger finger-Pelvic/thigh	0.000	0.998	0.001
M65.33 Trigger finger-Forearm	0.000	0.998	0.001
M65.32 Trigger finger-Upper arm	0.000	0.998	0.001
M65.31 Trigger finger-Shldr region	0.000	0.998	0.001
M65.30 Trigger finger-Mult sites	0.000	0.998	0.001
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.001	0.998	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.001	0.998	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.001	0.998	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.001	0.998	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.001	0.998	0.000
T63.4 Venom of other arthropods	0.000	0.998	0.002
O47 False labour	0.002	0.998	0.000
N18.5 Chronic kidney disease, stage 5	0.002	0.998	0.000
Z12.1 Special screening examination for neoplasm of intestinal tract	0.002	0.998	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.000	0.998	0.001
H65.4 Other chronic nonsuppurative otitis media	0.000	0.998	0.002
N15.8 Other specified renal tubulo-interstitial diseases	0.001	0.998	0.000
N15.0 Balkan nephropathy	0.001	0.998	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.001	0.998	0.000
H61.8 Other specified disorders of external ear	0.000	0.998	0.002
C81.1 Nodular sclerosis	0.000	0.998	0.002
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.998	0.001
M65.39 Trigger finger-Site unspec	0.000	0.998	0.001
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.998	0.002
O63.2 Delayed delivery of second twin, triplet, etc.	0.001	0.998	0.000
M07.38 Other psoriatic arthropathies (Other)	0.000	0.998	0.001
H65.1 Other acute nonsuppurative otitis media	0.000	0.998	0.001
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.001	0.998	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
D43.2 Brain, unspecified	0.002	0.998	0.000
H54.4 Blindness, one eye	0.000	0.998	0.002
J69.0 Pneumonitis due to food and vomit	0.002	0.998	0.000
L28.1 Prurigo nodularis	0.001	0.998	0.000
N15.1 Renal and perinephric abscess	0.001	0.998	0.000
N83.1 Corpus luteum cyst	0.000	0.998	0.002
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.001	0.998	0.000
T51.8 Other alcohols	0.000	0.998	0.001
T51.3 Fusel oil	0.000	0.998	0.001
T51.2 2-Propanol	0.000	0.998	0.001
T51.1 Methanol	0.000	0.998	0.001
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
T58 Toxic effect of carbon monoxide	0.000	0.998	0.002
T66-T78 Other and unspecified effects of external causes	0.000	0.998	0.002
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.998	0.001
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.998	0.002
N99.5 Malfunction of external stoma of urinary tract	0.001	0.998	0.000
O63.0 Prolonged first stage (of labour)	0.002	0.998	0.000
T71 Asphyxiation	0.000	0.998	0.001
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.998	0.001
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.998	0.001
H65.0 Acute serous otitis media	0.000	0.998	0.001
I71.0 Dissection of aorta [any part]	0.000	0.998	0.002
N05.1 Focal and segmental glomerular lesions	0.001	0.998	0.000
R49.1 Aphonia	0.001	0.998	0.000
S81.7 Multiple open wounds of lower leg	0.000	0.998	0.001
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.998	0.001
C81 Hodgkin's disease	0.000	0.998	0.002
L28 Lichen simplex chronicus and prurigo	0.001	0.998	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.002	0.998	0.000
T63 Toxic effect of contact with venomous animals	0.000	0.998	0.001
C71.9 Brain, unspecified	0.000	0.998	0.001
C71.3 Parietal lobe	0.000	0.998	0.001
C83.7 Burkitt's tumour	0.000	0.998	0.001
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.998	0.001
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.998	0.001
N15.9 Renal tubulo-interstitial disease, unspecified	0.001	0.998	0.000
Z35 Supervision of high-risk pregnancy	0.002	0.998	0.000
C81.0 Lymphocytic predominance	0.000	0.999	0.001
H27.1 Dislocation of lens	0.000	0.999	0.001
T66 Unspecified effects of radiation	0.000	0.999	0.001
I49.9 Cardiac arrhythmia, unspecified	0.000	0.999	0.001
S81.8 Open wound of other parts of lower leg	0.000	0.999	0.001
T63.9 Toxic effect of contact with unspecified venomous animal	0.000	0.999	0.001
C71.4 Occipital lobe	0.000	0.999	0.001
C71.1 Frontal lobe	0.000	0.999	0.001
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.999	0.001
Z35.0 Supervision of pregnancy with history of infertility	0.001	0.999	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.999	0.001
G70.0 Myasthenia gravis	0.000	0.999	0.001
K25.3 Acute without haemorrhage or perforation	0.001	0.999	0.000
L28.2 Other prurigo	0.001	0.999	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.001	0.999	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.999	0.001
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.999	0.001
Z35.4 Supervision of pregnancy with grand multiparity	0.001	0.999	0.000
N04 Nephrotic syndrome	0.001	0.999	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations