TreeWAS – Variant ID: rs2487928

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	0.954	0.046	0.000
I25 Chronic ischaemic heart disease	0.582	0.418	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.575	0.425	0.000
I25.3 Aneurysm of heart	0.500	0.500	0.000
I25.6 Silent myocardial ischaemia	0.417	0.583	0.000
I25.4 Coronary artery aneurysm	0.402	0.597	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.340	0.660	0.000
I25.5 Ischaemic cardiomyopathy	0.311	0.689	0.000
I25.2 Old myocardial infarction	0.154	0.846	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.090	0.910	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.955	0.045
Q21.1 Atrial septal defect	0.000	0.966	0.034
I20-I25 Ischaemic heart diseases	0.029	0.971	0.000
I20.9 Angina pectoris, unspecified	0.027	0.973	0.000
I20 Angina pectoris	0.024	0.976	0.000
S92.0 Fracture of calcaneus	0.000	0.980	0.020
A09.9 Gastroenteritis and colitis of unspecified origin	0.020	0.980	0.000
I23 Certain current complications following acute myocardial infarction	0.019	0.981	0.000
S92.01 Fracture of calcaneus (open)	0.000	0.985	0.015
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.014	0.986	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.014	0.986	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.014	0.986	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.014	0.986	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.014	0.986	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.014	0.986	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.014	0.986	0.000
I20.1 Angina pectoris with documented spasm	0.013	0.986	0.000
I31.3 Pericardial effusion (noninflammatory)	0.013	0.987	0.000
H65.3 Chronic mucoid otitis media	0.000	0.988	0.012
D14.0 Middle ear, nasal cavity and accessory sinuses	0.000	0.988	0.012
I23.8 Other current complications following acute myocardial infarction	0.012	0.988	0.000
I22 Subsequent myocardial infarction	0.011	0.989	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.990	0.009
H35.5 Hereditary retinal dystrophy	0.009	0.991	0.000
H65 Nonsuppurative otitis media	0.000	0.991	0.009
I21 Acute myocardial infarction	0.009	0.991	0.000
H35.8 Other specified retinal disorders	0.009	0.991	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.991	0.009
H35.6 Retinal haemorrhage	0.009	0.991	0.000
N76.2 Acute vulvitis	0.009	0.991	0.000
I22.8 Subsequent myocardial infarction of other sites	0.008	0.992	0.000
H35 Other retinal disorders	0.008	0.992	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.992	0.008
I21.0 Acute transmural myocardial infarction of anterior wall	0.008	0.992	0.000
Q21 Congenital malformations of cardiac septa	0.001	0.992	0.008
I21.3 Acute transmural myocardial infarction of unspecified site	0.008	0.992	0.000
H65.2 Chronic serous otitis media	0.000	0.992	0.008
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.007	0.993	0.000
I20.8 Other forms of angina pectoris	0.007	0.993	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.993	0.007
I22.1 Subsequent myocardial infarction of inferior wall	0.007	0.993	0.000
H35.2 Other proliferative retinopathy	0.007	0.993	0.000
N43.3 Hydrocele, unspecified	0.007	0.993	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.007	0.993	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.007	0.993	0.000
H65.0 Acute serous otitis media	0.000	0.994	0.006
B37.0 Candidal stomatitis	0.000	0.994	0.006
H35.7 Separation of retinal layers	0.006	0.994	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.006	0.994	0.000
I20.0 Unstable angina	0.006	0.994	0.000
H35.1 Retinopathy of prematurity	0.006	0.994	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.994	0.006
Q21.4 Aortopulmonary septal defect	0.001	0.994	0.006
Q21.2 Atrioventricular septal defect	0.001	0.994	0.006
Q21.8 Other congenital malformations of cardiac septa	0.001	0.994	0.006
N99.1 Postprocedural urethral stricture	0.000	0.994	0.006
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.000	0.994	0.006
N99.5 Malfunction of external stoma of urinary tract	0.000	0.994	0.006
N99.2 Postprocedural adhesions of vagina	0.000	0.994	0.006
Z95.1 Presence of aortocoronary bypass graft	0.006	0.994	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.994	0.006
N99.0 Postprocedural renal failure	0.000	0.994	0.006
D14 Benign neoplasm of middle ear and respiratory system	0.000	0.994	0.005
H65.1 Other acute nonsuppurative otitis media	0.000	0.995	0.005
Q21.3 Tetralogy of Fallot	0.001	0.995	0.005
H35.9 Retinal disorder, unspecified	0.005	0.995	0.000
N21.0 Calculus in bladder	0.000	0.995	0.005
I24 Other acute ischaemic heart diseases	0.005	0.995	0.000
D14.1 Larynx	0.000	0.995	0.005
H35.3 Degeneration of macula and posterior pole	0.005	0.995	0.000
K50.8 Other Crohn's disease	0.005	0.995	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.005	0.995	0.000
H31.0 Chorioretinal scars	0.005	0.995	0.000
I86.4 Gastric varices	0.000	0.996	0.004
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.996	0.004
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.996	0.004
D14.4 Respiratory system, unspecified	0.000	0.996	0.004
D14.2 Trachea	0.000	0.996	0.004
Q21.0 Ventricular septal defect	0.001	0.996	0.004
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.996	0.004
R84.5 Abnormal microbiological findings	0.004	0.996	0.000
H31 Other disorders of choroid	0.004	0.996	0.000
D23.4 Skin of scalp and neck	0.000	0.996	0.004
G93.2 Benign intracranial hypertension	0.000	0.996	0.004
I22.9 Subsequent myocardial infarction of unspecified site	0.003	0.996	0.000
H30-H36 Disorders of choroid and retina	0.004	0.996	0.000
H30 Chorioretinal inflammation	0.003	0.997	0.000
D14.3 Bronchus and lung	0.000	0.997	0.003
H31.9 Disorder of choroid, unspecified	0.003	0.997	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.997	0.003
I51.9 Heart disease, unspecified	0.003	0.997	0.000
H30.9 Chorioretinal inflammation, unspecified	0.003	0.997	0.000
I24.1 Dressler's syndrome	0.003	0.997	0.000
I21.9 Acute myocardial infarction, unspecified	0.003	0.997	0.000
I31 Other diseases of pericardium	0.003	0.997	0.000
N99-N99 Other disorders of the genitourinary system	0.000	0.997	0.003
B37.9 Candidiasis, unspecified	0.000	0.997	0.003
I34.0 Mitral (valve) insufficiency	0.003	0.997	0.000
H31.4 Choroidal detachment	0.003	0.997	0.000
H31.2 Hereditary choroidal dystrophy	0.003	0.997	0.000
I65.2 Occlusion and stenosis of carotid artery	0.003	0.997	0.000
H31.3 Choroidal haemorrhage and rupture	0.003	0.997	0.000
H30.2 Posterior cyclitis	0.003	0.997	0.000
C16.0 Cardia	0.000	0.997	0.003
H35.0 Background retinopathy and retinal vascular changes	0.003	0.997	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.003	0.997	0.000
B37 Candidiasis	0.000	0.997	0.003
Z80.4 Family history of malignant neoplasm of genital organs	0.000	0.997	0.003
I34.1 Mitral (valve) prolapse	0.003	0.997	0.000
H31.8 Other specified disorders of choroid	0.003	0.997	0.000
E61.1 Iron deficiency	0.000	0.997	0.003
Q38.7 Pharyngeal pouch	0.003	0.997	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.003	0.997	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.997	0.003
I34 Nonrheumatic mitral valve disorders	0.003	0.997	0.000
H30.8 Other chorioretinal inflammations	0.003	0.997	0.000
H30.1 Disseminated chorioretinal inflammation	0.003	0.997	0.000
H30.0 Focal chorioretinal inflammation	0.003	0.997	0.000
I31.0 Chronic adhesive pericarditis	0.003	0.997	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.001	0.997	0.002
G31.0 Circumscribed brain atrophy	0.003	0.997	0.000
O46.9 Antepartum haemorrhage, unspecified	0.003	0.997	0.000
B37.8 Candidiasis of other sites	0.000	0.997	0.003
H49.2 Sixth [abducent] nerve palsy	0.000	0.997	0.003
L98.0 Pyogenic granuloma	0.000	0.997	0.003
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.003	0.997	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.997	0.003
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.997	0.003
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.997	0.003
B37.2 Candidiasis of skin and nail	0.000	0.997	0.002
I31.8 Other specified diseases of pericardium	0.002	0.997	0.000
I31.2 Haemopericardium, not elsewhere classified	0.002	0.997	0.000
R59.9 Enlarged lymph nodes, unspecified	0.003	0.997	0.000
R06.6 Hiccough	0.000	0.997	0.002
W10.8 Other specified place	0.002	0.997	0.000
I35.8 Other aortic valve disorders	0.002	0.998	0.000
G59.0 Diabetic mononeuropathy	0.002	0.998	0.000
G97.8 Other postprocedural disorders of nervous system	0.000	0.998	0.002
H31.1 Choroidal degeneration	0.002	0.998	0.000
H34 Retinal vascular occlusions	0.002	0.998	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.002	0.998	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.002	0.998	0.000
N43 Hydrocele and spermatocele	0.002	0.998	0.000
B37.6 Candidal endocarditis	0.000	0.998	0.002
B37.5 Candidal meningitis	0.000	0.998	0.002
B37.4 Candidiasis of other urogenital sites	0.000	0.998	0.002
C61 Malignant neoplasm of prostate	0.000	0.998	0.002
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.002	0.998	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.002	0.998	0.000
S69.9 Unspecified injury of wrist and hand	0.000	0.998	0.002
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.998	0.002
S92.5 Fracture of other toe	0.000	0.998	0.002
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.002	0.998	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.002	0.998	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.000	0.998	0.002
G97.2 Intracranial hypotension following ventricular shunting	0.000	0.998	0.002
I34.8 Other nonrheumatic mitral valve disorders	0.002	0.998	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.001	0.998	0.002
H34.9 Retinal vascular occlusion, unspecified	0.002	0.998	0.000
N43.4 Spermatocele	0.002	0.998	0.000
I31.1 Chronic constrictive pericarditis	0.002	0.998	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.000	0.998	0.002
N21 Calculus of lower urinary tract	0.000	0.998	0.002
C78.2 Secondary malignant neoplasm of pleura	0.000	0.998	0.002
H35.4 Peripheral retinal degeneration	0.001	0.998	0.001
C60.9 Penis, unspecified	0.000	0.998	0.002
S92.50 Fracture of other toe (closed)	0.000	0.998	0.002
K10.8 Other specified diseases of jaws	0.002	0.998	0.000
B37.7 Candidal septicaemia	0.000	0.998	0.002
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.000	0.998	0.002
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.001	0.998	0.001
S92.4 Fracture of great toe	0.001	0.998	0.001
S92.1 Fracture of talus	0.001	0.998	0.002
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.998	0.002
G82.2 Paraplegia, unspecified	0.002	0.998	0.000
H34.0 Transient retinal artery occlusion	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.001	0.998	0.001
K01.0 Embedded teeth	0.002	0.998	0.000
N43.0 Encysted hydrocele	0.002	0.998	0.000
Q63.0 Accessory kidney	0.002	0.998	0.000
C60 Malignant neoplasm of penis	0.000	0.998	0.002
H34.1 Central retinal artery occlusion	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.001	0.998	0.001
H36 Retinal disorders in diseases classified elsewhere	0.002	0.998	0.000
M79.79 Fibromyalgia (Site unspecified)	0.000	0.998	0.002
C60.1 Glans penis	0.000	0.998	0.002
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
G82.5 Tetraplegia, unspecified	0.002	0.998	0.000
H92.0 Otalgia	0.000	0.998	0.002
R84 Abnormal findings in specimens from respiratory organs and thorax	0.002	0.998	0.000
B37.1 Pulmonary candidiasis	0.000	0.998	0.002
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.000	0.998	0.002
S92.91 Fracture of foot, unspecified (open)	0.001	0.998	0.001
S92.90 Fracture of foot, unspecified (closed)	0.001	0.998	0.001
C60.0 Prepuce	0.000	0.998	0.002
M86.66 Other chronic osteomyelitis (Lower leg)	0.002	0.998	0.000
N43.1 Infected hydrocele	0.002	0.998	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.000	0.998	0.002
M86.69 Other chronic osteomyelitis (Site unspecified)	0.002	0.998	0.000
D39.1 Ovary	0.002	0.998	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.000	0.998	0.002
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.002	0.998	0.000
N21.1 Calculus in urethra	0.000	0.998	0.002
M86.6 Other chronic osteomyelitis	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.001	0.998	0.001
B02.9 Zoster without complication	0.002	0.998	0.000
S92.11 Fracture of talus (open)	0.001	0.998	0.001
N42.2 Atrophy of prostate	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.001	0.998	0.001
S92.51 Fracture of other toe (open)	0.001	0.998	0.001
I44.7 Left bundle-branch block, unspecified	0.002	0.998	0.000
M88.9 Paget's disease of bone, unspecified	0.002	0.998	0.000
Q23.1 Congenital insufficiency of aortic valve	0.002	0.998	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.998	0.002
C60.8 Overlapping lesion of penis	0.000	0.998	0.002
C60.2 Body of penis	0.000	0.998	0.002
M70.4 Prepatellar bursitis	0.000	0.998	0.002
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.998	0.001
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.998	0.002
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.001	0.998	0.001
H36.8 Other retinal disorders in diseases classified elsewhere	0.002	0.998	0.000
N21.8 Other lower urinary tract calculus	0.000	0.998	0.002
N43.2 Other hydrocele	0.001	0.998	0.000
R84.7 Abnormal histological findings	0.002	0.998	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.002	0.998	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
I65.1 Occlusion and stenosis of basilar artery	0.002	0.998	0.000
R84.9 Unspecified abnormal finding	0.001	0.998	0.000
R84.8 Other abnormal findings	0.001	0.998	0.000
R84.6 Abnormal cytological findings	0.001	0.998	0.000
R84.4 Abnormal immunological findings	0.001	0.998	0.000
R84.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.998	0.000
R84.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.998	0.000
R84.1 Abnormal level of hormones	0.001	0.998	0.000
R84.0 Abnormal level of enzymes	0.001	0.998	0.000
G51.0 Bell's palsy	0.000	0.998	0.002
I65.8 Occlusion and stenosis of other precerebral artery	0.002	0.998	0.000
I95.1 Orthostatic hypotension	0.002	0.998	0.000
Z32.0 Pregnancy, not (yet) confirmed	0.002	0.998	0.000
Z52.4 Kidney donor	0.000	0.998	0.002
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.998	0.002
T14.0 Superficial injury of unspecified body region	0.000	0.998	0.002
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.002	0.998	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.001	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.001	0.998	0.001
O30.0 Twin pregnancy	0.002	0.998	0.000
E61 Deficiency of other nutrient elements	0.000	0.998	0.002
M86.68 Other chronic osteomyelitis (Other)	0.001	0.998	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.001	0.998	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.001	0.998	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.001	0.998	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.001	0.998	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.001	0.998	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.001	0.998	0.000
I73.9 Peripheral vascular disease, unspecified	0.002	0.998	0.000
Q38.8 Other congenital malformations of pharynx	0.001	0.998	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.001	0.998	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.001	0.998	0.000
Q38.3 Other congenital malformations of tongue	0.001	0.998	0.000
Q38.2 Macroglossia	0.001	0.998	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.001	0.998	0.000
G82 Paraplegia and tetraplegia	0.002	0.998	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.001	0.998	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.001	0.998	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.001	0.998	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.001	0.998	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.001	0.998	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.001	0.998	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.001	0.998	0.000
M70.49 Prepatellar bursitis-Site unspec	0.000	0.998	0.001
M70.48 Prepatellar bursitis-Other	0.000	0.998	0.001
M70.47 Prepatellar bursitis-Ankle/Foot	0.000	0.998	0.001
M70.45 Prepatellar bursitis-Pelvic/Thigh	0.000	0.998	0.001
M70.44 Prepatellar bursitis-Hand	0.000	0.998	0.001
M70.43 Prepatellar bursitis-Forearm	0.000	0.998	0.001
M70.42 Prepatellar bursitis-Upper arm	0.000	0.998	0.001
M70.41 Prepatellar bursitis-Shldr region	0.000	0.998	0.001
M70.40 Prepatellar bursitis-Mult sites	0.000	0.998	0.001
S92.10 Fracture of talus (closed)	0.001	0.998	0.001
Q27.3 Peripheral arteriovenous malformation	0.001	0.998	0.000
Q38.6 Other congenital malformations of mouth	0.001	0.998	0.000
Q38.1 Ankyloglossia	0.001	0.998	0.000
Q27 Other congenital malformations of peripheral vascular system	0.001	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.001	0.998	0.000
I24.8 Other forms of acute ischaemic heart disease	0.001	0.999	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.001	0.999	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.001	0.999	0.000
C60-C63 Malignant neoplasms of male genital organs	0.000	0.999	0.001
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.001	0.999	0.000
I27.2 Other secondary pulmonary hypertension	0.001	0.999	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.001	0.999	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.999	0.001
H57.8 Other specified disorders of eye and adnexa	0.000	0.999	0.001
R27.8 Other and unspecified lack of coordination	0.000	0.999	0.001
S67 Crushing injury of wrist and hand	0.000	0.999	0.001
C50.1 Central portion of breast	0.000	0.999	0.001
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.000	0.999	0.001
H83.0 Labyrinthitis	0.000	0.999	0.001
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.001	0.999	0.000
Z36 Antenatal screening	0.000	0.999	0.001
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.999	0.001
S50.9 Superficial injury of forearm, unspecified	0.000	0.999	0.001
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
E61.9 Deficiency of nutrient element, unspecified	0.000	0.999	0.001
E61.8 Deficiency of other specified nutrient elements	0.000	0.999	0.001
E61.7 Deficiency of multiple nutrient elements	0.000	0.999	0.001
E61.6 Vanadium deficiency	0.000	0.999	0.001
E61.5 Molybdenum deficiency	0.000	0.999	0.001
E61.4 Chromium deficiency	0.000	0.999	0.001
E61.3 Manganese deficiency	0.000	0.999	0.001
E61.0 Copper deficiency	0.000	0.999	0.001
G82.3 Flaccid tetraplegia	0.001	0.999	0.000
G82.0 Flaccid paraplegia	0.001	0.999	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.001	0.999	0.000
M79.63 Pain in limb (Forearm)	0.000	0.999	0.001
D37.0 Lip, oral cavity and pharynx	0.001	0.999	0.000
Q23.0 Congenital stenosis of aortic valve	0.001	0.999	0.000
F02.0 Dementia in Pick's disease	0.001	0.999	0.000
Q23.3 Congenital mitral insufficiency	0.001	0.999	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.001	0.999	0.000
Q27.4 Congenital phlebectasia	0.001	0.999	0.000
Q27.2 Other congenital malformations of renal artery	0.001	0.999	0.000
Q27.1 Congenital renal artery stenosis	0.001	0.999	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.001	0.999	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.001	0.999	0.000
C63 Malignant neoplasm of other and unspecified male genital organs	0.000	0.999	0.001
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.001	0.999	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.001	0.999	0.000
Q23.4 Hypoplastic left heart syndrome	0.001	0.999	0.000
Q23.2 Congenital mitral stenosis	0.001	0.999	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.999	0.001
Z85.4 Personal history of malignant neoplasm of genital organs	0.000	0.999	0.001
G51.3 Clonic hemifacial spasm	0.000	0.999	0.001
G82.1 Spastic paraplegia	0.001	0.999	0.000
M84.01 Malunion of fracture (Shoulder region)	0.000	0.999	0.001
M89.94 Disorder of bone, unspecified (Hand)	0.001	0.999	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.001	0.999	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.000	0.999	0.001
T86.0 Bone-marrow transplant rejection	0.001	0.999	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.001	0.999	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
S32.30 Fracture of ilium (closed)	0.000	0.999	0.001
B00.9 Herpesviral infection, unspecified	0.001	0.999	0.000
E61.2 Magnesium deficiency	0.000	0.999	0.001
K74.0 Hepatic fibrosis	0.000	0.999	0.001
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.001	0.999	0.000
Z36.5 Antenatal screening for isoimmunisation	0.000	0.999	0.001
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M81.98 Osteoporosis, unspecified (Other)	0.000	0.999	0.001
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.999	0.001
D46.9 Myelodysplastic syndrome, unspecified	0.001	0.999	0.000
G94.1 Hydrocephalus in neoplastic disease	0.000	0.999	0.001
M35.0 Sicca syndrome [Sjogren]	0.000	0.999	0.001
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.001	0.999	0.000
S69 Other and unspecified injuries of wrist and hand	0.000	0.999	0.001
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.001	0.999	0.000
C63.2 Scrotum	0.000	0.999	0.001
H70.9 Mastoiditis, unspecified	0.000	0.999	0.001
K29.0 Acute haemorrhagic gastritis	0.000	0.999	0.001
S80.1 Contusion of other and unspecified parts of lower leg	0.001	0.999	0.000
W49.0 Home	0.001	0.999	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.001	0.999	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.999	0.001
C63.9 Male genital organ, unspecified	0.000	0.999	0.001
C63.8 Overlapping lesion of male genital organs	0.000	0.999	0.001
C63.7 Other specified male genital organs	0.000	0.999	0.001
C63.1 Spermatic cord	0.000	0.999	0.001
C63.0 Epididymis	0.000	0.999	0.001
G82.4 Spastic tetraplegia	0.001	0.999	0.000
I63.8 Other cerebral infarction	0.000	0.999	0.001
M81.9 Osteoporosis, unspecified	0.000	0.999	0.001
S69.7 Multiple injuries of wrist and hand	0.000	0.999	0.001
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.001	0.999	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.001	0.999	0.000
D39.0 Uterus	0.001	0.999	0.000
H74.4 Polyp of middle ear	0.000	0.999	0.001
I51.8 Other ill-defined heart diseases	0.001	0.999	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.001	0.999	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.999	0.001
M89.90 Disorder of bone, unspecified (Multiple sites)	0.001	0.999	0.000
B02.2 Zoster with other nervous system involvement	0.001	0.999	0.000
J85.2 Abscess of lung without pneumonia	0.001	0.999	0.000
S60.8 Other superficial injuries of wrist and hand	0.000	0.999	0.001
Q26 Congenital malformations of great veins	0.001	0.999	0.000
Q25 Congenital malformations of great arteries	0.001	0.999	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.001	0.999	0.000
Q40 Other congenital malformations of upper alimentary tract	0.001	0.999	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.999	0.001
D48.7 Other specified sites	0.001	0.999	0.000
H70.8 Other mastoiditis and related conditions	0.000	0.999	0.001
Y52.3 Coronary vasodilators, not elsewhere classified	0.001	0.999	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.999	0.001
C91.1 Chronic lymphocytic leukaemia	0.001	0.999	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.001	0.999	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.001	0.999	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.001	0.999	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.999	0.001
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.999	0.001
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.999	0.001
H49.0 Third [oculomotor] nerve palsy	0.000	0.999	0.001
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.000	0.999	0.001
O46.8 Other antepartum haemorrhage	0.001	0.999	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.999	0.001
Q22 Congenital malformations of pulmonary and tricuspid valves	0.001	0.999	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.001	0.999	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.001	0.999	0.000
B02.1 Zoster meningitis	0.001	0.999	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.999	0.001
Q25.4 Other congenital malformations of aorta	0.001	0.999	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.001	0.999	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.001	0.999	0.000
Z36.9 Antenatal screening, unspecified	0.000	0.999	0.001
B02 Zoster [herpes zoster]	0.001	0.999	0.000
H49 Paralytic strabismus	0.000	0.999	0.001
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.999	0.001
F41.1 Generalised anxiety disorder	0.000	0.999	0.001
F43.2 Adjustment disorders	0.000	0.999	0.001
F51.5 Nightmares	0.001	0.999	0.000
H11.3 Conjunctival haemorrhage	0.000	0.999	0.001
N30.1 Interstitial cystitis (chronic)	0.000	0.999	0.001
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.001	0.999	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.001	0.999	0.000
Q20.6 Isomerism of atrial appendages	0.001	0.999	0.000
Q20.5 Discordant atrioventricular connexion	0.001	0.999	0.000
Q20.4 Double inlet ventricle	0.001	0.999	0.000
Q20.3 Discordant ventriculoarterial connexion	0.001	0.999	0.000
Q20.2 Double outlet left ventricle	0.001	0.999	0.000
Q20.1 Double outlet right ventricle	0.001	0.999	0.000
Q20.0 Common arterial trunk	0.001	0.999	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.001	0.999	0.000
Q25.8 Other congenital malformations of great arteries	0.001	0.999	0.000
Q25.5 Atresia of pulmonary artery	0.001	0.999	0.000
Q25.2 Atresia of aorta	0.001	0.999	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.001	0.999	0.000
Q26.8 Other congenital malformations of great veins	0.001	0.999	0.000
Q26.6 Portal vein-hepatic artery fistula	0.001	0.999	0.000
Q26.5 Anomalous portal venous connexion	0.001	0.999	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.001	0.999	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.001	0.999	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.001	0.999	0.000
Q26.1 Persistent left superior vena cava	0.001	0.999	0.000
Q26.0 Congenital stenosis of vena cava	0.001	0.999	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.999	0.001
Z58.1 Exposure to air pollution	0.001	0.999	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.001	0.999	0.000
Z82.1 Family history of blindness and visual loss	0.001	0.999	0.000
D86 Sarcoidosis	0.001	0.999	0.000
Q28 Other congenital malformations of circulatory system	0.001	0.999	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.999	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.999	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.999	0.001
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.001	0.999	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.001	0.999	0.000
D86.3 Sarcoidosis of skin	0.001	0.999	0.000
D86.0 Sarcoidosis of lung	0.001	0.999	0.000
H34.2 Other retinal artery occlusions	0.001	0.999	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.001	0.999	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.001	0.999	0.000
Q22.6 Hypoplastic right heart syndrome	0.001	0.999	0.000
Q22.4 Congenital tricuspid stenosis	0.001	0.999	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.001	0.999	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.001	0.999	0.000
Q22.0 Pulmonary valve atresia	0.001	0.999	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations