TreeWAS – Variant ID: rs2497155

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N20.1 Calculus of ureter	0.000	0.944	0.056
T43.2 Other and unspecified antidepressants	0.048	0.952	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.046	0.954	0.000
N20 Calculus of kidney and ureter	0.000	0.958	0.042
T36-T50 Poisoning by drugs, medicaments and biological substances	0.041	0.959	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.040	0.960	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.038	0.962	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.037	0.963	0.000
N20.9 Urinary calculus, unspecified	0.000	0.964	0.036
T46 Poisoning by agents primarily affecting the cardiovascular system	0.035	0.965	0.000
N20.2 Calculus of kidney with calculus of ureter	0.000	0.965	0.035
T43.6 Psychostimulants with abuse potential	0.034	0.965	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.034	0.966	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.034	0.966	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.034	0.966	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.033	0.966	0.000
T43.9 Psychotropic drug, unspecified	0.033	0.967	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.033	0.967	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.032	0.968	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.032	0.968	0.000
T36 Poisoning by systemic antibiotics	0.032	0.968	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.031	0.969	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.030	0.969	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.030	0.970	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.030	0.970	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.029	0.971	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.029	0.971	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.029	0.971	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.029	0.971	0.000
N20-N23 Urolithiasis	0.000	0.971	0.029
T40.2 Other opioids	0.029	0.971	0.000
N23 Unspecified renal colic	0.000	0.972	0.028
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.028	0.972	0.000
T46.1 Calcium-channel blockers	0.028	0.972	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.028	0.972	0.000
T40.4 Other synthetic narcotics	0.028	0.972	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.027	0.973	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.027	0.973	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.027	0.973	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.026	0.973	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.026	0.973	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.026	0.973	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.026	0.973	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.026	0.973	0.000
T44.0 Anticholinesterase agents	0.026	0.973	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.026	0.973	0.000
T40.1 Heroin	0.026	0.974	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.026	0.974	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.025	0.974	0.000
T46.7 Peripheral vasodilators	0.025	0.974	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.025	0.975	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.025	0.975	0.000
T47.4 Other laxatives	0.025	0.975	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.025	0.975	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.025	0.975	0.000
T40.8 Lysergide [LSD]	0.025	0.975	0.000
T40.7 Cannabis (derivatives)	0.025	0.975	0.000
T40.0 Opium	0.025	0.975	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.024	0.975	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.025	0.975	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.024	0.976	0.000
T36.8 Other systemic antibiotics	0.024	0.976	0.000
T36.0 Penicillins	0.024	0.976	0.000
T40.3 Methadone	0.024	0.976	0.000
T40.5 Cocaine	0.024	0.976	0.000
T36.4 Tetracyclines	0.024	0.976	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.024	0.976	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.024	0.976	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.023	0.976	0.000
T47.2 Stimulant laxatives	0.023	0.977	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.023	0.977	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.023	0.977	0.000
T47.7 Emetics	0.023	0.977	0.000
T47.5 Digestants	0.023	0.977	0.000
T47.3 Saline and osmotic laxatives	0.023	0.977	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.023	0.977	0.000
T37.5 Antiviral drugs	0.023	0.977	0.000
T37.4 Anthelminthics	0.023	0.977	0.000
T37.3 Other antiprotozoal drugs	0.023	0.977	0.000
T37.1 Antimycobacterial drugs	0.023	0.977	0.000
T37.0 Sulphonamides	0.023	0.977	0.000
T41.2 Other and unspecified general anaesthetics	0.023	0.977	0.000
T45.2 Vitamins, not elsewhere classified	0.023	0.977	0.000
T36.9 Systemic antibiotic, unspecified	0.023	0.977	0.000
T36.7 Antifungal antibiotics, systemically used	0.023	0.977	0.000
T36.6 Rifamycins	0.023	0.977	0.000
T36.5 Aminoglycosides	0.023	0.977	0.000
T36.2 Chloramphenicol group	0.023	0.977	0.000
T36.3 Macrolides	0.023	0.977	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.023	0.977	0.000
T47.6 Antidiarrhoeal drugs	0.023	0.977	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.022	0.978	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.022	0.978	0.000
T38.1 Thyroid hormones and substitutes	0.022	0.978	0.000
T41.5 Therapeutic gases	0.022	0.978	0.000
T41.4 Anaesthetic, unspecified	0.022	0.978	0.000
T41.3 Local anaesthetics	0.022	0.978	0.000
T41.1 Intravenous anaesthetics	0.022	0.978	0.000
T41.0 Inhaled anaesthetics	0.022	0.978	0.000
T49.9 Topical agent, unspecified	0.022	0.978	0.000
T49.8 Other topical agents	0.022	0.978	0.000
T49.7 Dental drugs, topically applied	0.022	0.978	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.022	0.978	0.000
T49.5 Ophthalmological drugs and preparations	0.022	0.978	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.022	0.978	0.000
T49.3 Emollients, demulcents and protectants	0.022	0.978	0.000
T49.2 Local astringents and local detergents	0.022	0.978	0.000
T49.1 Antipruritics	0.022	0.978	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.022	0.978	0.000
T38.9 Other and unspecified hormone antagonists	0.022	0.978	0.000
T38.7 Androgens and anabolic congeners	0.022	0.978	0.000
T38.4 Oral contraceptives	0.022	0.978	0.000
T38.2 Antithyroid drugs	0.022	0.978	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.022	0.978	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.021	0.978	0.000
T47.0 Histamine H(2)-receptor antagonists	0.021	0.978	0.000
T50.4 Drugs affecting uric acid metabolism	0.021	0.979	0.000
T38.0 Glucocorticoids and synthetic analogues	0.021	0.979	0.000
T38.5 Other oestrogens and progestogens	0.021	0.979	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.021	0.979	0.000
T48.4 Expectorants	0.021	0.979	0.000
T48.3 Antitussives	0.021	0.979	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.021	0.979	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.021	0.979	0.000
T48.0 Oxytocic drugs	0.021	0.979	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.021	0.979	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.021	0.979	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.000	0.979	0.021
T50.1 Loop [high-ceiling] diuretics	0.021	0.979	0.000
T45.4 Iron and its compounds	0.021	0.979	0.000
T50.8 Diagnostic agents	0.020	0.979	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.020	0.979	0.000
T45.8 Other primarily systemic and haematological agents	0.020	0.979	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.020	0.979	0.000
T45.6 Fibrinolysis-affecting drugs	0.020	0.979	0.000
T45.3 Enzymes, not elsewhere classified	0.020	0.979	0.000
T50.7 Analeptics and opioid receptor antagonists	0.020	0.979	0.000
T50.5 Appetite depressants	0.020	0.979	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.020	0.979	0.000
T50.0 Mineralocorticoids and their antagonists	0.020	0.979	0.000
T40.6 Other and unspecified narcotics	0.020	0.980	0.000
T48.5 Anti-common-cold drugs	0.020	0.980	0.000
S82.00 Fracture of patella (closed)	0.020	0.980	0.000
T45.0 Antiallergic and antiemetic drugs	0.020	0.980	0.000
S82.10 Fracture of upper end of tibia (closed)	0.020	0.980	0.000
T39.4 Antirheumatics, not elsewhere classified	0.019	0.980	0.000
T39.2 Pyrazolone derivatives	0.019	0.980	0.000
S82.0 Fracture of patella	0.019	0.981	0.000
T42.1 Iminostilbenes	0.019	0.981	0.000
S82 Fracture of lower leg, including ankle	0.019	0.981	0.000
S82.1 Fracture of upper end of tibia	0.019	0.981	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.019	0.981	0.000
H65.3 Chronic mucoid otitis media	0.000	0.982	0.018
H65-H75 Diseases of middle ear and mastoid	0.000	0.982	0.018
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.018	0.982	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.018	0.982	0.000
T39.0 Salicylates	0.018	0.982	0.000
H65 Nonsuppurative otitis media	0.000	0.982	0.018
K63.3 Ulcer of intestine	0.000	0.982	0.018
H72 Perforation of tympanic membrane	0.000	0.983	0.017
K63.2 Fistula of intestine	0.000	0.983	0.017
T42.5 Mixed antiepileptics, not elsewhere classified	0.017	0.983	0.000
T42.2 Succinimides and oxazolidinediones	0.017	0.983	0.000
S82.3 Fracture of lower end of tibia	0.017	0.983	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.983	0.017
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.017	0.983	0.000
T42.0 Hydantoin derivatives	0.017	0.983	0.000
H74 Other disorders of middle ear and mastoid	0.000	0.983	0.017
K63 Other diseases of intestine	0.000	0.983	0.017
S82.30 Fracture of lower end of tibia (closed)	0.016	0.984	0.000
F03 Unspecified dementia	0.016	0.984	0.000
H69 Other disorders of Eustachian tube	0.000	0.984	0.016
K63.9 Disease of intestine, unspecified	0.000	0.984	0.016
T42.3 Barbiturates	0.016	0.984	0.000
K63.4 Enteroptosis	0.000	0.984	0.016
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.000	0.985	0.015
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.000	0.985	0.015
F00-F09 Organic, including symptomatic, mental disorders	0.015	0.985	0.000
S82.2 Fracture of shaft of tibia	0.015	0.985	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.015	0.985	0.000
S82.5 Fracture of medial malleolus	0.015	0.985	0.000
H69.9 Eustachian tube disorder, unspecified	0.000	0.985	0.015
H73 Other disorders of tympanic membrane	0.000	0.985	0.015
H72.0 Central perforation of tympanic membrane	0.000	0.986	0.014
F05 Delirium, not induced by alcohol and other psychoactive substances	0.014	0.986	0.000
H66 Suppurative and unspecified otitis media	0.000	0.986	0.014
S82.7 Multiple fractures of lower leg	0.014	0.986	0.000
T45.5 Anticoagulants	0.014	0.986	0.001
H65.0 Acute serous otitis media	0.000	0.986	0.014
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.986	0.014
N21 Calculus of lower urinary tract	0.000	0.986	0.014
S82.01 Fracture of patella (open)	0.014	0.986	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.014	0.986	0.000
H68 Eustachian salpingitis and obstruction	0.000	0.986	0.014
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.013	0.987	0.000
H72.1 Attic perforation of tympanic membrane	0.000	0.987	0.013
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.987	0.013
H74.4 Polyp of middle ear	0.000	0.987	0.013
H74.1 Adhesive middle ear disease	0.000	0.987	0.013
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.987	0.013
H67 Otitis media in diseases classified elsewhere	0.000	0.987	0.013
S82.11 Fracture of upper end of tibia (open)	0.013	0.987	0.000
S82.9 Fracture of lower leg, part unspecified	0.013	0.987	0.000
H70 Mastoiditis and related conditions	0.000	0.987	0.013
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.987	0.013
H66.3 Other chronic suppurative otitis media	0.000	0.987	0.013
H65.4 Other chronic nonsuppurative otitis media	0.000	0.987	0.013
S80-S89 Injuries to the knee and lower leg	0.013	0.987	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.987	0.013
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.987	0.013
N20.0 Calculus of kidney	0.000	0.987	0.013
S82.20 Fracture of shaft of tibia (closed)	0.013	0.987	0.000
S82.8 Fractures of other parts of lower leg	0.013	0.987	0.000
H72.2 Other marginal perforations of tympanic membrane	0.000	0.987	0.012
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.012	0.988	0.000
F02 Dementia in other diseases classified elsewhere	0.012	0.988	0.000
K63.8 Other specified diseases of intestine	0.000	0.988	0.012
H74.0 Tympanosclerosis	0.000	0.988	0.012
F05.9 Delirium, unspecified	0.012	0.988	0.000
S82.4 Fracture of fibula alone	0.012	0.988	0.000
O36.5 Maternal care for poor foetal growth	0.000	0.988	0.012
F05.0 Delirium not superimposed on dementia, so described	0.012	0.988	0.000
O36 Maternal care for other known or suspected foetal problems	0.000	0.988	0.012
S82.31 Fracture of lower end of tibia (open)	0.012	0.988	0.000
T39.1 4-Aminophenol derivatives	0.012	0.988	0.000
F05.1 Delirium superimposed on dementia	0.012	0.988	0.000
T42.4 Benzodiazepines	0.012	0.988	0.000
H69.0 Patulous Eustachian tube	0.000	0.988	0.011
K63.1 Perforation of intestine (nontraumatic)	0.000	0.988	0.012
H71 Cholesteatoma of middle ear	0.000	0.988	0.012
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.988	0.011
S82.51 Fracture of medial malleolus (open)	0.011	0.988	0.000
O36.9 Maternal care for foetal problem, unspecified	0.000	0.989	0.011
F80-F89 Disorders of psychological development	0.011	0.989	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.989	0.011
S82.6 Fracture of lateral malleolus	0.011	0.989	0.000
H73.0 Acute myringitis	0.000	0.989	0.011
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.989	0.011
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.011	0.989	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.011	0.989	0.000
S82.50 Fracture of medial malleolus (closed)	0.011	0.989	0.000
F06.7 Mild cognitive disorder	0.011	0.989	0.000
H72.8 Other perforations of tympanic membrane	0.000	0.989	0.011
Chapter V Mental and behavioural disorders	0.011	0.989	0.000
F80 Specific developmental disorders of speech and language	0.011	0.989	0.000
H68.1 Obstruction of Eustachian tube	0.000	0.989	0.011
H70.9 Mastoiditis, unspecified	0.000	0.989	0.011
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.989	0.011
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.011	0.989	0.000
F09 Unspecified organic or symptomatic mental disorder	0.011	0.989	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.010	0.989	0.000
S82.70 Multiple fractures of lower leg (closed)	0.010	0.989	0.000
F05.8 Other delirium	0.010	0.989	0.000
S86 Injury of muscle and tendon at lower leg level	0.010	0.989	0.000
F06.3 Organic mood [affective] disorders	0.010	0.990	0.000
S80 Superficial injury of lower leg	0.010	0.990	0.000
S82.71 Multiple fractures of lower leg (open)	0.010	0.990	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.010	0.990	0.000
F31.9 Bipolar affective disorder, unspecified	0.010	0.990	0.000
F80.1 Expressive language disorder	0.010	0.990	0.000
H69.8 Other specified disorders of Eustachian tube	0.000	0.990	0.010
N21.8 Other lower urinary tract calculus	0.000	0.990	0.010
F07.2 Postconcussional syndrome	0.010	0.990	0.000
H68.0 Eustachian salpingitis	0.000	0.990	0.010
S82.21 Fracture of shaft of tibia (open)	0.010	0.990	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.990	0.010
S80.9 Superficial injury of lower leg, unspecified	0.010	0.990	0.000
F31 Bipolar affective disorder	0.010	0.990	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.000	0.990	0.010
H73.1 Chronic myringitis	0.000	0.990	0.010
H65.2 Chronic serous otitis media	0.000	0.990	0.010
O70.1 Second degree perineal laceration during delivery	0.000	0.990	0.010
F02.8 Dementia in other specified diseases classified elsewhere	0.010	0.990	0.000
F02.0 Dementia in Pick's disease	0.010	0.990	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.010	0.990	0.000
F06.5 Organic dissociative disorder	0.010	0.990	0.000
F06.4 Organic anxiety disorder	0.010	0.990	0.000
F06.1 Organic catatonic disorder	0.010	0.990	0.000
F06.0 Organic hallucinosis	0.010	0.990	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.010	0.990	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.990	0.010
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.990	0.010
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.990	0.010
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.990	0.010
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.990	0.010
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.990	0.010
H70.2 Petrositis	0.000	0.990	0.010
F30-F39 Mood [affective] disorders	0.010	0.990	0.000
F81 Specific developmental disorders of scholastic skills	0.010	0.990	0.000
H70.0 Acute mastoiditis	0.000	0.990	0.010
S84 Injury of nerves at lower leg level	0.010	0.990	0.000
H66.9 Otitis media, unspecified	0.000	0.990	0.010
F10.0 Acute intoxication	0.010	0.990	0.000
F84 Pervasive developmental disorders	0.010	0.990	0.000
S85 Injury of blood vessels at lower leg level	0.009	0.990	0.000
H70.8 Other mastoiditis and related conditions	0.000	0.990	0.009
S88 Traumatic amputation of lower leg	0.009	0.990	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.009	0.990	0.000
F07.0 Organic personality disorder	0.009	0.990	0.000
S89 Other and unspecified injuries of lower leg	0.009	0.991	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.991	0.009
S87 Crushing injury of lower leg	0.009	0.991	0.000
S82.81 Fractures of other parts of lower leg (open)	0.009	0.991	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.009	0.991	0.000
F02.3 Dementia in Parkinson's disease	0.009	0.991	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.009	0.991	0.000
S82.86 Maisonneuve's fracture	0.009	0.991	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.009	0.991	0.000
F02.2 Dementia in Huntington's disease	0.009	0.991	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.009	0.991	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.009	0.991	0.000
F07.1 Postencephalitic syndrome	0.009	0.991	0.000
O36.8 Maternal care for other specified foetal problems	0.000	0.991	0.009
F00 Dementia in Alzheimer's disease	0.009	0.991	0.000
H66.0 Acute suppurative otitis media	0.000	0.991	0.009
S82.41 Fracture of fibula alone (open)	0.009	0.991	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.991	0.009
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.991	0.009
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.991	0.009
O36.2 Maternal care for hydrops foetalis	0.000	0.991	0.009
S83.6 Sprain and strain of other and unspecified parts of knee	0.009	0.991	0.000
O36.4 Maternal care for intra-uterine death	0.000	0.991	0.009
O36.6 Maternal care for excessive foetal growth	0.000	0.991	0.009
Y40.9 Systemic antibiotic, unspecified	0.000	0.991	0.009
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.991	0.009
O70 Perineal laceration during delivery	0.000	0.991	0.009
F80.2 Receptive language disorder	0.008	0.991	0.000
H70.1 Chronic mastoiditis	0.000	0.991	0.008
S86.8 Injury of other muscles and tendons at lower leg level	0.009	0.991	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.009	0.991	0.000
N21.1 Calculus in urethra	0.000	0.991	0.008
O48 Prolonged pregnancy	0.000	0.991	0.009
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.991	0.009
S82.61 Fracture of lateral malleolus (open)	0.008	0.991	0.000
S80.0 Contusion of knee	0.008	0.991	0.000
F70-F79 Mental retardation	0.008	0.991	0.000
S83.1 Dislocation of knee	0.008	0.991	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.992	0.008
F84.5 Asperger's syndrome	0.008	0.992	0.000
F89 Unspecified disorder of psychological development	0.008	0.992	0.000
F88 Other disorders of psychological development	0.008	0.992	0.000
F83 Mixed specific developmental disorders	0.008	0.992	0.000
F82 Specific developmental disorder of motor function	0.008	0.992	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.008	0.992	0.000
F39 Unspecified mood [affective] disorder	0.008	0.992	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.008	0.992	0.000
S83.3 Tear of articular cartilage of knee, current	0.008	0.992	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.992	0.008
F10 Mental and behavioural disorders due to use of alcohol	0.008	0.992	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.008	0.992	0.000
F60-F69 Disorders of adult personality and behaviour	0.008	0.992	0.000
S83.0 Dislocation of patella	0.008	0.992	0.000
F99-F99 Unspecified mental disorder	0.008	0.992	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.008	0.992	0.000
K63.0 Abscess of intestine	0.000	0.992	0.008
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.008	0.992	0.000
S81 Open wound of lower leg	0.008	0.992	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.008	0.992	0.000
O60-O75 Complications of labour and delivery	0.000	0.992	0.008
F80.9 Developmental disorder of speech and language, unspecified	0.008	0.992	0.000
F80.8 Other developmental disorders of speech and language	0.008	0.992	0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.008	0.992	0.000
F80.0 Specific speech articulation disorder	0.008	0.992	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.008	0.992	0.000
F01 Vascular dementia	0.007	0.992	0.001
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.992	0.008
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.008	0.992	0.000
F31.8 Other bipolar affective disorders	0.008	0.992	0.000
F31.7 Bipolar affective disorder, currently in remission	0.008	0.992	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.008	0.992	0.000
S86.0 Injury of Achilles tendon	0.008	0.992	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.008	0.992	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.008	0.992	0.000
S83.7 Injury to multiple structures of knee	0.008	0.992	0.000
O36.1 Maternal care for other isoimmunisation	0.000	0.992	0.008
S81.0 Open wound of knee	0.008	0.992	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.008	0.992	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.992	0.008
O69.8 Labour and delivery complicated by other cord complications	0.000	0.992	0.008
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.007	0.992	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.000	0.992	0.008
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.007	0.992	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.007	0.992	0.000
F38 Other mood [affective] disorders	0.007	0.992	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.007	0.993	0.000
S80.7 Multiple superficial injuries of lower leg	0.007	0.993	0.000
K62.4 Stenosis of anus and rectum	0.000	0.993	0.007
O30 Multiple gestation	0.000	0.993	0.007
F81.8 Other developmental disorders of scholastic skills	0.007	0.993	0.000
F81.3 Mixed disorder of scholastic skills	0.007	0.993	0.000
F81.2 Specific disorder of arithmetical skills	0.007	0.993	0.000
F81.1 Specific spelling disorder	0.007	0.993	0.000
F81.0 Specific reading disorder	0.007	0.993	0.000
O70.3 Fourth degree perineal laceration during delivery	0.000	0.993	0.007
S84.9 Injury of unspecified nerve at lower leg level	0.007	0.993	0.000
S84.8 Injury of other nerves at lower leg level	0.007	0.993	0.000
S84.7 Injury of multiple nerves at lower leg level	0.007	0.993	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.007	0.993	0.000
S84.0 Injury of tibial nerve at lower leg level	0.007	0.993	0.000
O16 Unspecified maternal hypertension	0.000	0.993	0.007
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.993	0.007
S85.1 Injury of (anterior)(posterior) tibial artery	0.007	0.993	0.000
S82.40 Fracture of fibula alone (closed)	0.007	0.993	0.000
O71 Other obstetric trauma	0.000	0.993	0.007
F84.9 Pervasive developmental disorder, unspecified	0.007	0.993	0.000
F84.8 Other pervasive developmental disorders	0.007	0.993	0.000
F84.4 Overactive disorder associated with mental retardation and stereotyped movements	0.007	0.993	0.000
F84.3 Other childhood disintegrative disorder	0.007	0.993	0.000
F84.2 Rett's syndrome	0.007	0.993	0.000
F84.1 Atypical autism	0.007	0.993	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.007	0.993	0.000
S85.8 Injury of other blood vessels at lower leg level	0.007	0.993	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.007	0.993	0.000
S85.5 Injury of popliteal vein	0.007	0.993	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.007	0.993	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.007	0.993	0.000
S85.2 Injury of peroneal artery	0.007	0.993	0.000
S85.0 Injury of popliteal artery	0.007	0.993	0.000
F34 Persistent mood [affective] disorders	0.007	0.993	0.000
F30 Manic episode	0.007	0.993	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.993	0.007
O31 Complications specific to multiple gestation	0.000	0.993	0.007
S88.9 Traumatic amputation of lower leg, level unspecified	0.007	0.993	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.007	0.993	0.000
S88.0 Traumatic amputation at knee level	0.007	0.993	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.000	0.993	0.007
N21.0 Calculus in bladder	0.000	0.993	0.007
S89.9 Unspecified injury of lower leg	0.007	0.993	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.007	0.993	0.000
O41 Other disorders of amniotic fluid and membranes	0.000	0.993	0.007
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.993	0.007
S87.0 Crushing injury of knee	0.007	0.993	0.000
S89.7 Multiple injuries of lower leg	0.007	0.993	0.000
S89.1 Other specified injuries of lower leg	0.007	0.993	0.000
S89.0 Multiple injuries of lower leg	0.007	0.993	0.000
F84.0 Childhood autism	0.007	0.993	0.000
O00-O08 Pregnancy with abortive outcome	0.000	0.993	0.007
F31.6 Bipolar affective disorder, current episode mixed	0.007	0.993	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.007	0.993	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.007	0.993	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.993	0.007
F79 Unspecified mental retardation	0.007	0.993	0.000
O00.1 Tubal pregnancy	0.000	0.993	0.007
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.000	0.993	0.007
O70.9 Perineal laceration during delivery, unspecified	0.000	0.993	0.007
S89.8 Other specified injuries of lower leg	0.007	0.993	0.000
F10.4 Withdrawal state with delirium	0.007	0.993	0.000
O04 Medical abortion	0.000	0.993	0.007
O69.0 Labour and delivery complicated by prolapse of cord	0.000	0.993	0.007
O33 Maternal care for known or suspected disproportion	0.000	0.993	0.007
O46.8 Other antepartum haemorrhage	0.000	0.993	0.007
O46.9 Antepartum haemorrhage, unspecified	0.000	0.993	0.007
F50 Eating disorders	0.007	0.993	0.000
O44 Placenta praevia	0.000	0.993	0.007
O00 Ectopic pregnancy	0.000	0.993	0.007
F00.1 Dementia in Alzheimer's disease with late onset	0.006	0.993	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.006	0.993	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.000	0.993	0.007
F10.5 Psychotic disorder	0.007	0.993	0.000
F60 Specific personality disorders	0.007	0.993	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.993	0.007
O45 Premature separation of placenta [abruptio placentae]	0.000	0.993	0.006
F10.9 Unspecified mental and behavioural disorder	0.006	0.993	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.994	0.006
F70 Mild mental retardation	0.006	0.994	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.006	0.994	0.000
F78 Other mental retardation	0.006	0.994	0.000
F73 Profound mental retardation	0.006	0.994	0.000
F72 Severe mental retardation	0.006	0.994	0.000
F71 Moderate mental retardation	0.006	0.994	0.000
O30.0 Twin pregnancy	0.000	0.994	0.006
O69.5 Labour and delivery complicated by vascular lesion of cord	0.000	0.994	0.006
O69.4 Labour and delivery complicated by vasa praevia	0.000	0.994	0.006
O69.3 Labour and delivery complicated by short cord	0.000	0.994	0.006
F69 Unspecified disorder of adult personality and behaviour	0.006	0.994	0.000
F10.3 Withdrawal state	0.006	0.994	0.000
O70.2 Third degree perineal laceration during delivery	0.000	0.994	0.006
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.994	0.006
F18 Mental and behavioural disorders due to use of volatile solvents	0.006	0.994	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.006	0.994	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.994	0.006
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.994	0.006
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.994	0.006
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.994	0.006
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.994	0.006
O73 Retained placenta and membranes, without haemorrhage	0.000	0.994	0.006
O12.0 Gestational oedema	0.000	0.994	0.006
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.006	0.994	0.000
F15.1 Harmful use	0.006	0.994	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.006	0.994	0.000
F65 Disorders of sexual preference	0.006	0.994	0.000
F63 Habit and impulse disorders	0.006	0.994	0.000
F99 Mental disorder, not otherwise specified	0.006	0.994	0.000
F10.7 Residual and late-onset psychotic disorder	0.006	0.994	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.994	0.006
F64 Gender identity disorders	0.006	0.994	0.000
F68 Other disorders of adult personality and behaviour	0.006	0.994	0.000
O04.9 Complete or unspecified, without complication	0.000	0.994	0.006
O41.0 Oligohydramnios	0.000	0.994	0.006
F52 Sexual dysfunction, not caused by organic disorder or disease	0.006	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations