TreeWAS – Variant ID: rs2507980

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	1.000
E03 Other hypothyroidism	0.000	1.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	1.000
# Top node	0.001	0.999
L40-L45 Papulosquamous disorders	0.003	0.997
L40 Psoriasis	0.003	0.997
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.005	0.995
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.005	0.995
E65-E68 Obesity and other hyperalimentation	0.009	0.991
M06.9 Rheumatoid arthritis, unspecified	0.010	0.990
L57 Skin changes due to chronic exposure to nonionising radiation	0.010	0.990
M06 Other rheumatoid arthritis	0.012	0.988
L40.5 Arthropathic psoriasis	0.012	0.988
M05-M14 Inflammatory polyarthropathies	0.013	0.987
L40.9 Psoriasis, unspecified	0.013	0.987
D50-D53 Nutritional anaemias	0.014	0.986
E66 Obesity	0.015	0.985
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.015	0.985
E66.8 Other obesity	0.017	0.983
D50 Iron deficiency anaemia	0.017	0.983
L57.0 Actinic keratosis	0.018	0.982
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.019	0.981
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.020	0.980
D50.9 Iron deficiency anaemia, unspecified	0.020	0.980
L00-L08 Infections of the skin and subcutaneous tissue	0.030	0.970
Chapter I Certain infectious and parasitic diseases	0.037	0.963
E70-E90 Metabolic disorders	0.040	0.960
Chapter VIII Diseases of the ear and mastoid process	0.046	0.954
B35-B49 Mycoses	0.046	0.954
L02 Cutaneous abscess, furuncle and carbuncle	0.047	0.953
B37 Candidiasis	0.049	0.951
B37.8 Candidiasis of other sites	0.052	0.948
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.056	0.944
H65-H75 Diseases of middle ear and mastoid	0.078	0.922
L20-L30 Dermatitis and eczema	0.087	0.913
E06 Thyroiditis	0.092	0.908
H72 Perforation of tympanic membrane	0.093	0.907
M07 Psoriatic and enteropathic arthropathies	0.095	0.905
B25-B34 Other viral diseases	0.096	0.904
M45-M49 Spondylopathies	0.097	0.903
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.102	0.898
H72.9 Perforation of tympanic membrane, unspecified	0.102	0.898
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.107	0.893
B37.0 Candidal stomatitis	0.108	0.892
M45 Ankylosing spondylitis	0.108	0.892
Chapter V Mental and behavioural disorders	0.118	0.882
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.122	0.878
M45.X9 Ankylosing spondylitis (Site unspecified)	0.124	0.876
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.124	0.876
B34 Viral infection of unspecified site	0.133	0.867
E10-E14 Diabetes mellitus	0.135	0.865
M05 Seropositive rheumatoid arthritis	0.148	0.852
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.148	0.852
E05 Thyrotoxicosis [hyperthyroidism]	0.149	0.851
M07.3 Other psoriatic arthropathies	0.154	0.846
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.156	0.844
E10 Insulin-dependent diabetes mellitus	0.163	0.837
H65 Nonsuppurative otitis media	0.166	0.834
H80-H83 Diseases of inner ear	0.166	0.834
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.166	0.833
D80-D89 Certain disorders involving the immune mechanism	0.168	0.832
E06.3 Autoimmune thyroiditis	0.169	0.831
B34.9 Viral infection, unspecified	0.174	0.826
E89.0 Postprocedural hypothyroidism	0.176	0.824
M95.0 Acquired deformity of nose	0.178	0.822
L29 Pruritus	0.184	0.816
E87 Other disorders of fluid, electrolyte and acid-base balance	0.187	0.813
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.187	0.813
L08 Other local infections of skin and subcutaneous tissue	0.189	0.811
M35 Other systemic involvement of connective tissue	0.189	0.811
M35.3 Polymyalgia rheumatica	0.192	0.808
M20-M25 Other joint disorders	0.192	0.808
D68 Other coagulation defects	0.197	0.803
E86 Volume depletion	0.197	0.803
B20-B24 Human immunodeficiency virus [HIV] disease	0.200	0.800
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.201	0.799
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.206	0.794
M06.0 Seronegative rheumatoid arthritis	0.207	0.793
E20-E35 Disorders of other endocrine glands	0.208	0.791
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.211	0.789
B35 Dermatophytosis	0.226	0.774
L29.0 Pruritus ani	0.226	0.774
F00-F09 Organic, including symptomatic, mental disorders	0.230	0.770
D86 Sarcoidosis	0.232	0.768
M07.30 Other psoriatic arthropathies (Multiple sites)	0.232	0.767
Chapter IX Diseases of the circulatory system	0.235	0.765
D55-D59 Haemolytic anaemias	0.240	0.760
B99-B99 Other infectious diseases	0.240	0.759
E05.0 Thyrotoxicosis with diffuse goitre	0.241	0.759
E73 Lactose intolerance	0.243	0.757
E27 Other disorders of adrenal gland	0.243	0.757
M05.9 Seropositive rheumatoid arthritis, unspecified	0.245	0.755
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.246	0.754
H72.0 Central perforation of tympanic membrane	0.250	0.750
E66.0 Obesity due to excess calories	0.250	0.750
M00-M03 Infectious arthropathies	0.252	0.748
E88 Other metabolic disorders	0.253	0.747
E10.9 Without complications	0.255	0.745
E87.1 Hypo-osmolality and hyponatraemia	0.256	0.744
L56 Other acute skin changes due to ultraviolet radiation	0.257	0.743
H80 Otosclerosis	0.259	0.741
A50-A64 Infections with a predominantly sexual mode of transmission	0.260	0.740
E27.1 Primary adrenocortical insufficiency	0.268	0.732
E10.3 With ophthalmic complications	0.269	0.731
H65.9 Nonsuppurative otitis media, unspecified	0.270	0.730
Chapter XXII Codes for special purposes	0.272	0.728
L27 Dermatitis due to substances taken internally	0.273	0.727
L30 Other dermatitis	0.274	0.726
L05 Pilonidal cyst	0.278	0.722
E65 Localised adiposity	0.281	0.719
I60-I69 Cerebrovascular diseases	0.282	0.718
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.283	0.717
E03.5 Myxoedema coma	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.283	0.717
Chapter XVI Certain conditions originating in the perinatal period	0.283	0.717
B34.8 Other viral infections of unspecified site	0.284	0.716
M07.39 Other psoriatic arthropathies (Site unspecified)	0.284	0.716
I70-I79 Diseases of arteries, arterioles and capillaries	0.285	0.715
E80 Disorders of porphyrin and bilirubin metabolism	0.285	0.715
L44 Other papulosquamous disorders	0.285	0.715
L41 Parapsoriasis	0.285	0.715
L45 Papulosquamous disorders in diseases classified elsewhere	0.285	0.715
L40.8 Other psoriasis	0.285	0.715
L40.4 Guttate psoriasis	0.285	0.715
L40.3 Pustulosis palmaris et plantaris	0.285	0.715
L40.2 Acrodermatitis continua	0.285	0.715
L40.1 Generalised pustular psoriasis	0.285	0.715
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.286	0.714
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.287	0.713
L58 Radiodermatitis	0.287	0.713
L55 Sunburn	0.287	0.713
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.287	0.713
F40-F48 Neurotic, stress-related and somatoform disorders	0.288	0.712
F30-F39 Mood [affective] disorders	0.288	0.712
E67 Other hyperalimentation	0.289	0.711
E68 Sequelae of hyperalimentation	0.289	0.711
M35.0 Sicca syndrome [Sjogren]	0.290	0.710
M06.98 Rheumatoid arthritis, unspecified (Other)	0.290	0.710
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.290	0.710
L57.5 Actinic granuloma	0.290	0.710
L57.3 Poikiloderma of Civatte	0.290	0.710
L57.2 Cutis rhomboidalis nuchae	0.290	0.710
L57.1 Actinic reticuloid	0.290	0.710
M14 Arthropathies in other diseases classified elsewhere	0.291	0.709
M06.8 Other specified rheumatoid arthritis	0.291	0.709
M06.2 Rheumatoid bursitis	0.291	0.709
M06.1 Adult-onset Still's disease	0.291	0.709
M12 Other specific arthropathies	0.292	0.708
M09 Juvenile arthritis in diseases classified elsewhere	0.292	0.708
M08 Juvenile arthritis	0.292	0.708
E66.1 Drug-induced obesity	0.294	0.706
D50.1 Sideropenic dysphagia	0.295	0.704
D86.9 Sarcoidosis, unspecified	0.297	0.703
E74 Other disorders of carbohydrate metabolism	0.302	0.697
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.302	0.697
D68.5 Primary Thrombophilia	0.304	0.696
E50-E64 Other nutritional deficiencies	0.304	0.696
L04 Acute lymphadenitis	0.305	0.695
L01 Impetigo	0.305	0.695
L00 Staphylococcal scalded skin syndrome	0.305	0.695
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.306	0.694
H73 Other disorders of tympanic membrane	0.308	0.691
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.309	0.690
A75-A79 Rickettsioses	0.309	0.690
A70-A74 Other diseases caused by chlamydiae	0.309	0.690
A65-A69 Other spirochaetal diseases	0.309	0.690
A20-A28 Certain zoonotic bacterial diseases	0.309	0.690
E10.1 With ketoacidosis	0.310	0.690
F60-F69 Disorders of adult personality and behaviour	0.310	0.690
M34 Systemic sclerosis	0.310	0.689
I20-I25 Ischaemic heart diseases	0.311	0.689
F80-F89 Disorders of psychological development	0.311	0.689
E84 Cystic fibrosis	0.311	0.688
E79 Disorders of purine and pyrimidine metabolism	0.311	0.688
E77 Disorders of glycoprotein metabolism	0.311	0.688
E76 Disorders of glycosaminoglycan metabolism	0.311	0.688
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.311	0.688
E72 Other disorders of amino-acid metabolism	0.311	0.688
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.311	0.688
E70 Disorders of aromatic amino-acid metabolism	0.311	0.688
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.311	0.688
E06.9 Thyroiditis, unspecified	0.312	0.688
E87.2 Acidosis	0.313	0.687
I73 Other peripheral vascular diseases	0.314	0.686
B48 Other mycoses, not elsewhere classified	0.316	0.684
B47 Mycetoma	0.316	0.684
B46 Zygomycosis	0.316	0.684
B45 Cryptococcosis	0.316	0.684
B43 Chromomycosis and phaeomycotic abscess	0.316	0.684
B42 Sporotrichosis	0.316	0.684
B41 Paracoccidioidomycosis	0.316	0.684
B40 Blastomycosis	0.316	0.684
B39 Histoplasmosis	0.316	0.684
B38 Coccidioidomycosis	0.316	0.684
B36 Other superficial mycoses	0.316	0.684
B24 Unspecified human immunodeficiency virus [HIV] disease	0.316	0.684
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.317	0.683
B25 Cytomegaloviral disease	0.317	0.683
B37.7 Candidal septicaemia	0.318	0.682
B37.6 Candidal endocarditis	0.318	0.682
B37.5 Candidal meningitis	0.318	0.682
L57.4 Cutis laxa senilis	0.319	0.681
I21 Acute myocardial infarction	0.320	0.680
M46 Other inflammatory spondylopathies	0.322	0.678
L10-L14 Bullous disorders	0.323	0.677
I69 Sequelae of cerebrovascular disease	0.323	0.676
D68.9 Coagulation defect, unspecified	0.324	0.676
H80.9 Otosclerosis, unspecified	0.325	0.675
H60-H62 Diseases of external ear	0.325	0.675
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.327	0.673
A15-A19 Tuberculosis	0.328	0.672
H83 Other diseases of inner ear	0.331	0.669
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.332	0.668
E40-E46 Malnutrition	0.332	0.668
I73.0 Raynaud's syndrome	0.335	0.665
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.336	0.664
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.336	0.664
M35.7 Hypermobility syndrome	0.337	0.663
L28 Lichen simplex chronicus and prurigo	0.337	0.663
B50-B64 Protozoal diseases	0.338	0.662
M11 Other crystal arthropathies	0.338	0.662
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.339	0.661
H68 Eustachian salpingitis and obstruction	0.339	0.661
H67 Otitis media in diseases classified elsewhere	0.339	0.661
H70 Mastoiditis and related conditions	0.341	0.659
E03.8 Other specified hypothyroidism	0.341	0.659
I21.9 Acute myocardial infarction, unspecified	0.344	0.656
I77 Other disorders of arteries and arterioles	0.345	0.655
L24 Irritant contact dermatitis	0.345	0.655
L21 Seborrhoeic dermatitis	0.345	0.655
L26 Exfoliative dermatitis	0.345	0.655
L22 Diaper [napkin] dermatitis	0.345	0.655
D86.0 Sarcoidosis of lung	0.346	0.654
E66.2 Extreme obesity with alveolar hypoventilation	0.347	0.653
E10.2 With renal complications	0.348	0.652
H65.2 Chronic serous otitis media	0.348	0.652
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.349	0.651
E06.5 Other chronic thyroiditis	0.349	0.651
E06.4 Drug-induced thyroiditis	0.349	0.651
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.349	0.651
E06.1 Subacute thyroiditis	0.349	0.651
E06.0 Acute thyroiditis	0.349	0.651
H72.1 Attic perforation of tympanic membrane	0.350	0.650
B15-B19 Viral hepatitis	0.351	0.649
M07.6 Other enteropathic arthropathies	0.351	0.649
M07.5 Arthropathy in ulcerative colitis	0.351	0.649
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.351	0.649
M07.2 Psoriatic spondylitis	0.351	0.649
M07.1 Arthritis mutilans	0.351	0.649
M07.0 Distal interphalangeal psoriatic arthropathy	0.351	0.649
B30 Viral conjunctivitis	0.352	0.648
B27 Infectious mononucleosis	0.352	0.648
B26 Mumps	0.352	0.648
M06.4 Inflammatory polyarthropathy	0.352	0.647
F05 Delirium, not induced by alcohol and other psychoactive substances	0.352	0.648
D52 Folate deficiency anaemia	0.353	0.647
L20 Atopic dermatitis	0.353	0.647
F31 Bipolar affective disorder	0.353	0.647
E10.5 With peripheral circulatory complications	0.354	0.646
H65.4 Other chronic nonsuppurative otitis media	0.355	0.645
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.359	0.641
E85 Amyloidosis	0.359	0.641
M99 Biomechanical lesions, not elsewhere classified	0.360	0.640
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.361	0.639
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.361	0.639
M45.X6 Ankylosing spondylitis (Lumbar region)	0.361	0.639
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.361	0.639
M45.X4 Ankylosing spondylitis (Thoracic region)	0.361	0.639
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.361	0.639
M45.X2 Ankylosing spondylitis (Cervical region)	0.361	0.639
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.361	0.639
B37.9 Candidiasis, unspecified	0.362	0.638
D51 Vitamin B12 deficiency anaemia	0.362	0.638
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.362	0.638
I05-I09 Chronic rheumatic heart diseases	0.362	0.638
B35.1 Tinea unguium	0.363	0.637
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.363	0.637
L25 Unspecified contact dermatitis	0.363	0.636
B90-B94 Sequelae of infectious and parasitic diseases	0.365	0.635
M06.3 Rheumatoid nodule	0.365	0.634
E83 Disorders of mineral metabolism	0.366	0.634
E14 Unspecified diabetes mellitus	0.367	0.633
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.367	0.633
F42 Obsessive-compulsive disorder	0.368	0.632
M49 Spondylopathies in diseases classified elsewhere	0.369	0.631
D66 Hereditary factor VIII deficiency	0.369	0.631
B37.4 Candidiasis of other urogenital sites	0.370	0.630
D67 Hereditary factor IX deficiency	0.370	0.630
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.370	0.630
I21.2 Acute transmural myocardial infarction of other sites	0.370	0.630
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.372	0.628
E89.8 Other postprocedural endocrine and metabolic disorders	0.372	0.628
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.372	0.628
E89.5 Postprocedural testicular hypofunction	0.372	0.628
E89.4 Postprocedural ovarian failure	0.372	0.628
E89.1 Postprocedural hypoinsulinaemia	0.372	0.628
B65-B83 Helminthiases	0.373	0.627
M91-M94 Chondropathies	0.374	0.626
E07 Other disorders of thyroid	0.374	0.626
E22 Hyperfunction of pituitary gland	0.374	0.626
B85-B89 Pediculosis, acariasis and other infestations	0.375	0.625
B37.1 Pulmonary candidiasis	0.375	0.624
M60-M63 Disorders of muscles	0.375	0.624
E10.4 With neurological complications	0.376	0.624
B37.2 Candidiasis of skin and nail	0.378	0.621
B34.3 Parvovirus infection, unspecified	0.379	0.621
B34.2 Coronavirus infection, unspecified	0.379	0.621
B34.1 Enterovirus infection, unspecified	0.379	0.621
B34.0 Adenovirus infection, unspecified	0.379	0.621
E12 Malnutrition-related diabetes mellitus	0.380	0.620
L23 Allergic contact dermatitis	0.380	0.619
L05.0 Pilonidal cyst with abscess	0.381	0.619
D50.8 Other iron deficiency anaemias	0.381	0.619
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.382	0.618
D59 Acquired haemolytic anaemia	0.382	0.618
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.382	0.618
D70-D77 Other diseases of blood and blood-forming organs	0.382	0.618
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.384	0.616
E89.3 Postprocedural hypopituitarism	0.384	0.616
D68.0 Von Willebrand's disease	0.385	0.615
I21.1 Acute transmural myocardial infarction of inferior wall	0.385	0.615
E87.7 Fluid overload	0.386	0.614
B99 Other and unspecified infectious diseases	0.386	0.614
I69.3 Sequelae of cerebral infarction	0.387	0.613
F70-F79 Mental retardation	0.387	0.613
E73.9 Lactose intolerance, unspecified	0.388	0.612
D60-D64 Aplastic and other anaemias	0.388	0.612
M05.8 Other seropositive rheumatoid arthritis	0.389	0.611
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.389	0.611
M05.2 Rheumatoid vasculitis	0.389	0.611
M05.1 Rheumatoid lung disease	0.389	0.611
M05.0 Felty's syndrome	0.389	0.611
E05.9 Thyrotoxicosis, unspecified	0.389	0.611
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.389	0.611
M95.8 Other specified acquired deformities of musculoskeletal system	0.389	0.611
M95.5 Acquired deformity of pelvis	0.389	0.611
M95.4 Acquired deformity of chest and rib	0.389	0.611
M95.3 Acquired deformity of neck	0.389	0.611
M95.2 Other acquired deformity of head	0.389	0.611
M95.1 Cauliflower ear	0.389	0.611
E05.5 Thyroid crisis or storm	0.390	0.610
E05.4 Thyrotoxicosis factitia	0.390	0.610
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.390	0.610
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.390	0.610
L27.0 Generalised skin eruption due to drugs and medicaments	0.391	0.609
I67 Other cerebrovascular diseases	0.393	0.607
M07.38 Other psoriatic arthropathies (Other)	0.394	0.606
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.394	0.606
M07.36 Other psoriatic arthropathies (Lower leg)	0.394	0.606
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.394	0.606
M07.34 Other psoriatic arthropathies (Hand)	0.394	0.606
M07.33 Other psoriatic arthropathies (Forearm)	0.394	0.606
M07.32 Other psoriatic arthropathies (Upper arm)	0.394	0.606
M07.31 Other psoriatic arthropathies (Shoulder region)	0.394	0.606
H65.3 Chronic mucoid otitis media	0.395	0.605
D69 Purpura and other haemorrhagic conditions	0.398	0.602
I63 Cerebral infarction	0.399	0.601
B34.4 Papovirus infection, unspecified	0.399	0.601
I62 Other nontraumatic intracranial haemorrhage	0.400	0.600
E10.0 With coma	0.400	0.600
E10.7 With multiple complications	0.400	0.600
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.400	0.600
L29.9 Pruritus, unspecified	0.402	0.598
H65.1 Other acute nonsuppurative otitis media	0.402	0.598
H65.0 Acute serous otitis media	0.402	0.598
H82 Vertiginous syndromes in diseases classified elsewhere	0.402	0.598
D53 Other nutritional anaemias	0.402	0.598
F43 Reaction to severe stress, and adjustment disorders	0.403	0.597
D84 Other immunodeficiencies	0.403	0.597
D83 Common variable immunodeficiency	0.403	0.597
D82 Immunodeficiency associated with other major defects	0.403	0.597
D81 Combined immunodeficiencies	0.403	0.597
E89.2 Postprocedural hypoparathyroidism	0.405	0.595
E27.4 Other and unspecified adrenocortical insufficiency	0.406	0.594
L30.8 Other specified dermatitis	0.406	0.594
H69 Other disorders of Eustachian tube	0.408	0.592
I77.1 Stricture of artery	0.408	0.592
L42 Pityriasis rosea	0.411	0.589
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.412	0.588
L08.8 Other specified local infections of skin and subcutaneous tissue	0.412	0.588
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.413	0.587
M30 Polyarteritis nodosa and related conditions	0.413	0.586
D68.2 Hereditary deficiency of other clotting factors	0.414	0.586
L29.8 Other pruritus	0.415	0.585
L29.3 Anogenital pruritus, unspecified	0.415	0.585
L29.1 Pruritus scroti	0.415	0.585
I60 Subarachnoid haemorrhage	0.416	0.584
E87.4 Mixed disorder of acid-base balance	0.417	0.583
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.417	0.583
L08.1 Erythrasma	0.418	0.582
L08.0 Pyoderma	0.418	0.582
M35.9 Systemic involvement of connective tissue, unspecified	0.419	0.581
M35.8 Other specified systemic involvement of connective tissue	0.419	0.581
M35.6 Relapsing panniculitis [Weber-Christian]	0.419	0.581
M35.5 Multifocal fibrosclerosis	0.419	0.581
M35.4 Diffuse (eosinophilic) fasciitis	0.419	0.581
M35.2 Behcet's disease	0.419	0.581
M35.1 Other overlap syndromes	0.419	0.581
F20 Schizophrenia	0.419	0.581
F00 Dementia in Alzheimer's disease	0.419	0.581
M34.9 Systemic sclerosis, unspecified	0.419	0.581
M46.9 Inflammatory spondylopathy, unspecified	0.420	0.580
I70 Atherosclerosis	0.420	0.580
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.420	0.579
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.421	0.579
M32 Systemic lupus erythematosus	0.421	0.579
M00 Pyogenic arthritis	0.422	0.578
I22 Subsequent myocardial infarction	0.422	0.578
F05.9 Delirium, unspecified	0.423	0.577
D68.4 Acquired coagulation factor deficiency	0.424	0.576
D68.1 Hereditary factor XI deficiency	0.424	0.576
F42.9 Obsessive-compulsive disorder, unspecified	0.425	0.575
B33 Other viral diseases, not elsewhere classified	0.426	0.574
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions	0.426	0.574
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases	0.426	0.574
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms	0.426	0.574
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases	0.426	0.574
M22 Disorders of patella	0.426	0.574
F99-F99 Unspecified mental disorder	0.427	0.573
F81 Specific developmental disorders of scholastic skills	0.428	0.572
I77.6 Arteritis, unspecified	0.430	0.570
M06.08 Seronegative rheumatoid arthritis (Other)	0.431	0.569
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.431	0.569
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.431	0.569
M06.04 Seronegative rheumatoid arthritis (Hand)	0.431	0.569
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.431	0.569
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.431	0.569
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.431	0.569
B35.3 Tinea pedis	0.431	0.569
L40.0 Psoriasis vulgaris	0.432	0.568
E35 Disorders of endocrine glands in diseases classified elsewhere	0.432	0.567
E32 Diseases of thymus	0.432	0.567
E31 Polyglandular dysfunction	0.432	0.567
E30 Disorders of puberty, not elsewhere classified	0.432	0.567
E25 Adrenogenital disorders	0.432	0.567
E20 Hypoparathyroidism	0.432	0.567
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.434	0.566
F30 Manic episode	0.434	0.566
R21 Rash and other nonspecific skin eruption	0.435	0.565
L43 Lichen planus	0.435	0.565
H72.2 Other marginal perforations of tympanic membrane	0.435	0.565
I67.8 Other specified cerebrovascular diseases	0.435	0.565
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.437	0.563
E10.8 With unspecified complications	0.438	0.562
F40 Phobic anxiety disorders	0.439	0.561
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.439	0.561
F22 Persistent delusional disorders	0.439	0.561
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.440	0.560
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.440	0.559
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.441	0.559
F60 Specific personality disorders	0.443	0.557
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.443	0.557
B37.3 Candidiasis of vulva and vagina	0.444	0.556
M10 Gout	0.444	0.556
F03 Unspecified dementia	0.444	0.556
B35.9 Dermatophytosis, unspecified	0.445	0.555
B35.8 Other dermatophytoses	0.445	0.555
B35.6 Tinea cruris	0.445	0.555
B35.5 Tinea imbricata	0.445	0.555
B35.4 Tinea corporis	0.445	0.555
B35.2 Tinea manuum	0.445	0.555
B35.0 Tinea barbae and tinea capitis	0.445	0.555
I08 Multiple valve diseases	0.445	0.555
H72.8 Other perforations of tympanic membrane	0.446	0.554
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.448	0.552
F09 Unspecified organic or symptomatic mental disorder	0.448	0.552
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.448	0.552
D86.3 Sarcoidosis of skin	0.449	0.551
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.449	0.551
D86.1 Sarcoidosis of lymph nodes	0.449	0.551
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.450	0.550
H83.0 Labyrinthitis	0.450	0.550
F01 Vascular dementia	0.450	0.550
F25 Schizoaffective disorders	0.450	0.550
L50-L54 Urticaria and erythema	0.452	0.548
I00-I02 Acute rheumatic fever	0.452	0.548
A80-A89 Viral infections of the central nervous system	0.452	0.548
E26 Hyperaldosteronism	0.453	0.547
M13 Other arthritis	0.454	0.546
D57 Sickle-cell disorders	0.455	0.545
D56 Thalassaemia	0.455	0.545
D55 Anaemia due to enzyme disorders	0.455	0.545
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.456	0.544
R26 Abnormalities of gait and mobility	0.456	0.544
D68.6 Other Thrombophilia	0.457	0.543
E73.8 Other lactose intolerance	0.457	0.543
E73.1 Secondary lactase deficiency	0.457	0.543
E73.0 Congenital lactase deficiency	0.457	0.543
E27.5 Adrenomedullary hyperfunction	0.457	0.543
E27.3 Drug-induced adrenocortical insufficiency	0.457	0.543
E27.2 Addisonian crisis	0.457	0.543
E27.0 Other adrenocortical overactivity	0.457	0.543
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.458	0.542

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations