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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2516484
log Bayes Factor = 81.6627
Chromosome 6   position 31,496,381  (GRCh37) Explore rs2516484 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
0.000 0.000 1.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
J45 Asthma
0.000 0.000 1.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
J47 Bronchiectasis
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
F40-F48 Neurotic, stress-related and somatoform disorders
1.000 0.000 0.000
J30-J39 Other diseases of upper respiratory tract
0.000 0.001 0.999
Chapter X Diseases of the respiratory system
0.000 0.001 0.999
J33 Nasal polyp
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.002 0.998
F41 Other anxiety disorders
0.998 0.002 0.000
E00-E07 Disorders of thyroid gland
0.000 0.003 0.997
L40-L45 Papulosquamous disorders
0.996 0.004 0.000
F30-F39 Mood [affective] disorders
0.995 0.005 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.005 0.995
Chapter XII Diseases of the skin and subcutaneous tissue
0.993 0.007 0.000
J33.9 Nasal polyp, unspecified
0.000 0.010 0.990
E05.9 Thyrotoxicosis, unspecified
0.000 0.012 0.988
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.987 0.013 0.000
L40.0 Psoriasis vulgaris
0.986 0.014 0.000
F41.2 Mixed anxiety and depressive disorder
0.980 0.020 0.000
T39.1 4-Aminophenol derivatives
0.974 0.026 0.000
J33.0 Polyp of nasal cavity
0.000 0.028 0.972
M07.3 Other psoriatic arthropathies
0.970 0.030 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.967 0.033 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.966 0.034 0.000
F60-F69 Disorders of adult personality and behaviour
0.965 0.035 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.037 0.963
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.962 0.038 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.957 0.043 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.956 0.044 0.000
F41.9 Anxiety disorder, unspecified
0.948 0.052 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.944 0.056 0.000
Chapter II Neoplasms
0.944 0.056 0.000
C15-C26 Malignant neoplasms of digestive organs
0.940 0.060 0.000
F32 Depressive episode
0.938 0.062 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.938 0.062 0.000
F17.1 Harmful use
0.933 0.067 0.000
Chapter XXI Factors influencing health status and contact with health services
0.930 0.070 0.000
Chapter VI Diseases of the nervous system
0.930 0.070 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.929 0.071 0.000
F60 Specific personality disorders
0.927 0.073 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.925 0.075 0.000
C18 Malignant neoplasm of colon
0.921 0.079 0.000
C18.7 Sigmoid colon
0.920 0.080 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.915 0.085 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.913 0.087 0.000
F33 Recurrent depressive disorder
0.904 0.096 0.000
J30 Vasomotor and allergic rhinitis
0.000 0.099 0.901
F31 Bipolar affective disorder
0.901 0.099 0.000
E07 Other disorders of thyroid
0.000 0.102 0.897
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.103 0.897
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.891 0.109 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.888 0.112 0.000
Z42 Follow-up care involving plastic surgery
0.885 0.115 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.884 0.116 0.000
F45 Somatoform disorders
0.874 0.126 0.000
J33.8 Other polyp of sinus
0.000 0.128 0.872
J36 Peritonsillar abscess
0.000 0.134 0.866
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.136 0.864
Q20-Q28 Congenital malformations of the circulatory system
0.863 0.137 0.000
T43.2 Other and unspecified antidepressants
0.863 0.137 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.861 0.139 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.859 0.141 0.000
M07 Psoriatic and enteropathic arthropathies
0.857 0.143 0.001
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.855 0.145 0.000
T51 Toxic effect of alcohol
0.852 0.148 0.000
F60.9 Personality disorder, unspecified
0.851 0.149 0.000
Z40 Prophylactic surgery
0.849 0.151 0.000
G20-G26 Extrapyramidal and movement disorders
0.846 0.154 0.000
F30 Manic episode
0.846 0.154 0.000
F32.9 Depressive episode, unspecified
0.844 0.156 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.157 0.843
Z53.0 Procedure not carried out because of contraindication
0.843 0.157 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.837 0.163 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.836 0.164 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.201 0.166 0.633
F41.1 Generalised anxiety disorder
0.834 0.166 0.000
F60.3 Emotionally unstable personality disorder
0.833 0.167 0.000
C21 Malignant neoplasm of anus and anal canal
0.831 0.169 0.000
L40.1 Generalised pustular psoriasis
0.831 0.169 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.828 0.172 0.000
J00-J06 Acute upper respiratory infections
0.000 0.174 0.826
J31.0 Chronic rhinitis
0.000 0.175 0.825
G70-G73 Diseases of myoneural junction and muscle
0.823 0.177 0.000
J45.0 Predominantly allergic asthma
0.000 0.177 0.823
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.822 0.178 0.000
T42.4 Benzodiazepines
0.821 0.179 0.000
Q21 Congenital malformations of cardiac septa
0.819 0.181 0.000
J42 Unspecified chronic bronchitis
0.000 0.182 0.818
S90-S99 Injuries to the ankle and foot
0.817 0.183 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.817 0.183 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.813 0.186 0.000
F44 Dissociative [conversion] disorders
0.813 0.187 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.807 0.193 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.805 0.195 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.803 0.197 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.802 0.198 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.802 0.198 0.000
T51.0 Ethanol
0.800 0.200 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.800 0.200 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.795 0.205 0.000
J30.1 Allergic rhinitis due to pollen
0.000 0.208 0.792
R15 Faecal incontinence
0.792 0.208 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.792 0.208 0.000
L42 Pityriasis rosea
0.791 0.209 0.000
J44 Other chronic obstructive pulmonary disease
0.000 0.210 0.790
D37-D48 Neoplasms of uncertain or unknown behaviour
0.789 0.211 0.000
L40.8 Other psoriasis
0.789 0.211 0.000
S40-S49 Injuries to the shoulder and upper arm
0.786 0.213 0.001
R94 Abnormal results of function studies
0.787 0.213 0.000
F45.8 Other somatoform disorders
0.785 0.215 0.000
C18.9 Colon, unspecified
0.784 0.216 0.000
F69 Unspecified disorder of adult personality and behaviour
0.783 0.217 0.000
F32.1 Moderate depressive episode
0.783 0.217 0.000
F42 Obsessive-compulsive disorder
0.783 0.217 0.000
R94.5 Abnormal results of liver function studies
0.782 0.218 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.781 0.219 0.000
M05-M14 Inflammatory polyarthropathies
0.775 0.224 0.001
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.776 0.224 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.775 0.225 0.000
Q21.1 Atrial septal defect
0.774 0.226 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.773 0.227 0.000
S10-S19 Injuries to the neck
0.771 0.229 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.771 0.229 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.770 0.230 0.000
J60-J70 Lung diseases due to external agents
0.000 0.231 0.769
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.768 0.232 0.000
R21 Rash and other nonspecific skin eruption
0.768 0.232 0.000
E10-E14 Diabetes mellitus
0.137 0.234 0.629
C17 Malignant neoplasm of small intestine
0.765 0.234 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.761 0.239 0.000
J03 Acute tonsillitis
0.000 0.240 0.760
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.760 0.240 0.000
Q60-Q64 Congenital malformations of the urinary system
0.759 0.241 0.000
F32.0 Mild depressive episode
0.758 0.242 0.000
F43 Reaction to severe stress, and adjustment disorders
0.758 0.242 0.000
G70 Myasthenia gravis and other myoneural disorders
0.758 0.242 0.000
Chapter XI Diseases of the digestive system
0.757 0.243 0.000
R17 Unspecified jaundice
0.757 0.243 0.000
K80 Cholelithiasis
0.756 0.244 0.000
T79-T79 Certain early complications of trauma
0.755 0.245 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.754 0.245 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.754 0.246 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.753 0.247 0.000
Z53.8 Procedure not carried out for other reasons
0.753 0.247 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.752 0.248 0.000
F31.9 Bipolar affective disorder, unspecified
0.751 0.249 0.000
S32 Fracture of lumbar spine and pelvis
0.751 0.249 0.000
G24 Dystonia
0.750 0.250 0.000
R10 Abdominal and pelvic pain
0.749 0.251 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.748 0.252 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.747 0.252 0.000
F33.9 Recurrent depressive disorder, unspecified
0.747 0.253 0.000
G62 Other polyneuropathies
0.746 0.254 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.745 0.255 0.000
C20 Malignant neoplasm of rectum
0.745 0.255 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.745 0.255 0.000
T39.0 Salicylates
0.744 0.256 0.000
R12 Heartburn
0.743 0.257 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.743 0.257 0.000
Z43 Attention to artificial openings
0.743 0.257 0.000
R18 Ascites
0.741 0.259 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.259 0.741
S80-S89 Injuries to the knee and lower leg
0.740 0.260 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.738 0.262 0.000
Chapter IX Diseases of the circulatory system
0.738 0.262 0.000
Q50-Q56 Congenital malformations of genital organs
0.735 0.264 0.000
Z41 Procedures for purposes other than remedying health state
0.733 0.267 0.000
C21.1 Anal canal
0.731 0.269 0.000
F40 Phobic anxiety disorders
0.731 0.269 0.000
G61 Inflammatory polyneuropathy
0.731 0.269 0.000
E06 Thyroiditis
0.000 0.273 0.727
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.726 0.274 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.724 0.276 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.723 0.277 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.277 0.723
J30.3 Other allergic rhinitis
0.000 0.277 0.723
S92 Fracture of foot, except ankle
0.722 0.278 0.000
F17.2 Dependence syndrome
0.722 0.278 0.000
Q80-Q89 Other congenital malformations
0.721 0.279 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.720 0.280 0.000
Z51 Other medical care
0.720 0.280 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.720 0.280 0.000
G90-G99 Other disorders of the nervous system
0.718 0.282 0.000
Z45 Adjustment and management of implanted device
0.717 0.283 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.717 0.283 0.000
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.000 0.283 0.717
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
J45.8 Mixed asthma
0.000 0.283 0.717
J45.1 Nonallergic asthma
0.000 0.283 0.717
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C64-C68 Malignant neoplasms of urinary tract
0.717 0.283 0.000
F48 Other neurotic disorders
0.717 0.283 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.717 0.283 0.000
J33.1 Polypoid sinus degeneration
0.000 0.284 0.716
C34 Malignant neoplasm of bronchus and lung
0.716 0.284 0.000
K70-K77 Diseases of liver
0.716 0.284 0.000
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.284 0.716
E03.1 Congenital hypothyroidism without goitre
0.000 0.284 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
Z00-Z13 Persons encountering health services for examination and investigation
0.716 0.284 0.000
F41.8 Other specified anxiety disorders
0.715 0.285 0.000
F41.3 Other mixed anxiety disorders
0.715 0.285 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.285 0.715
E00 Congenital iodine-deficiency syndrome
0.000 0.285 0.715
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.285 0.715
L44 Other papulosquamous disorders
0.714 0.286 0.000
L41 Parapsoriasis
0.714 0.286 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.714 0.286 0.000
F38 Other mood [affective] disorders
0.714 0.286 0.000
F34 Persistent mood [affective] disorders
0.714 0.286 0.000
F39 Unspecified mood [affective] disorder
0.714 0.286 0.000
E05.8 Other thyrotoxicosis
0.000 0.287 0.713
E05.5 Thyroid crisis or storm
0.000 0.287 0.713
E05.4 Thyrotoxicosis factitia
0.000 0.287 0.713
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.287 0.713
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.287 0.713
J37 Chronic laryngitis and laryngotracheitis
0.000 0.287 0.713
J84 Other interstitial pulmonary diseases
0.000 0.287 0.713
D00-D09 In situ neoplasms
0.713 0.287 0.000
J03.9 Acute tonsillitis, unspecified
0.000 0.287 0.713
L10-L14 Bullous disorders
0.712 0.288 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.712 0.288 0.000
J81 Pulmonary oedema
0.000 0.289 0.711
G70.0 Myasthenia gravis
0.711 0.289 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.710 0.290 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.710 0.290 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.708 0.292 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.708 0.292 0.000
T39.4 Antirheumatics, not elsewhere classified
0.708 0.292 0.000
T39.2 Pyrazolone derivatives
0.708 0.292 0.000
G20 Parkinson's disease
0.706 0.294 0.000
E03.8 Other specified hypothyroidism
0.000 0.295 0.704
J32 Chronic sinusitis
0.000 0.298 0.702
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.700 0.300 0.000
F30.0 Hypomania
0.697 0.303 0.000
S70-S79 Injuries to the hip and thigh
0.696 0.304 0.001
M07.38 Other psoriatic arthropathies (Other)
0.695 0.304 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.695 0.304 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.695 0.304 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.695 0.304 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.695 0.304 0.000
Q00-Q07 Congenital malformations of the nervous system
0.695 0.305 0.000
G40-G47 Episodic and paroxysmal disorders
0.693 0.307 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.693 0.307 0.000
F68 Other disorders of adult personality and behaviour
0.692 0.308 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.692 0.308 0.000
F65 Disorders of sexual preference
0.692 0.308 0.000
F64 Gender identity disorders
0.692 0.308 0.000
F63 Habit and impulse disorders
0.692 0.308 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.692 0.308 0.000
F61 Mixed and other personality disorders
0.692 0.308 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.691 0.308 0.000
S31 Open wound of abdomen, lower back and pelvis
0.691 0.309 0.000
Chapter VIII Diseases of the ear and mastoid process
0.691 0.309 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.690 0.310 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.690 0.310 0.000
T42.3 Barbiturates
0.690 0.310 0.000
T42.2 Succinimides and oxazolidinediones
0.690 0.310 0.000
T42.1 Iminostilbenes
0.690 0.310 0.000
T42.0 Hydantoin derivatives
0.690 0.310 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.689 0.310 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.689 0.311 0.000
F99-F99 Unspecified mental disorder
0.689 0.311 0.000
F80-F89 Disorders of psychological development
0.687 0.312 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.687 0.313 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.687 0.313 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.687 0.313 0.000
K80.4 Calculus of bile duct with cholecystitis
0.687 0.313 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.686 0.314 0.000
Q35-Q37 Cleft lip and cleft palate
0.686 0.314 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.686 0.314 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.686 0.314 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.686 0.314 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.686 0.314 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.686 0.314 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.686 0.314 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.686 0.314 0.000
F11 Mental and behavioural disorders due to use of opioids
0.686 0.314 0.000
Z45.1 Adjustment and management of infusion pump
0.684 0.316 0.000
G24.9 Dystonia, unspecified
0.681 0.319 0.000
F44.9 Dissociative [conversion] disorder, unspecified
0.679 0.321 0.000
F17.9 Unspecified mental and behavioural disorder
0.677 0.323 0.000
F17.8 Other mental and behavioural disorders
0.677 0.323 0.000
F17.7 Residual and late-onset psychotic disorder
0.677 0.323 0.000
F17.6 Amnesic syndrome
0.677 0.323 0.000
F17.5 Psychotic disorder
0.677 0.323 0.000
F17.4 Withdrawal state with delirium
0.677 0.323 0.000
F17.3 Withdrawal state
0.677 0.323 0.000
F17.0 Acute intoxication
0.677 0.323 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.677 0.323 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.674 0.326 0.000
C23 Malignant neoplasm of gallbladder
0.674 0.326 0.000
Chapter XXII Codes for special purposes
0.673 0.327 0.000
F30.9 Manic episode, unspecified
0.673 0.327 0.000
F32.8 Other depressive episodes
0.673 0.327 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.672 0.328 0.000
T43.9 Psychotropic drug, unspecified
0.672 0.328 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.672 0.328 0.000
T43.6 Psychostimulants with abuse potential
0.672 0.328 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.672 0.328 0.000
C79 Secondary malignant neoplasm of other sites
0.672 0.328 0.000
K83 Other diseases of biliary tract
0.672 0.328 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.671 0.329 0.000
Z51.1 Chemotherapy session for neoplasm
0.670 0.330 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.669 0.331 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.668 0.332 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.668 0.332 0.000
G62.9 Polyneuropathy, unspecified
0.667 0.333 0.000
Z49 Care involving dialysis
0.666 0.333 0.000
Z44 Fitting and adjustment of external prosthetic device
0.666 0.334 0.000
J39 Other diseases of upper respiratory tract
0.000 0.334 0.666
J30.4 Allergic rhinitis, unspecified
0.000 0.335 0.665
F60.8 Other specific personality disorders
0.665 0.335 0.000
F60.7 Dependent personality disorder
0.665 0.335 0.000
F60.6 Anxious [avoidant] personality disorder
0.665 0.335 0.000
F60.5 Anankastic personality disorder
0.665 0.335 0.000
F60.4 Histrionic personality disorder
0.665 0.335 0.000
F60.2 Dissocial personality disorder
0.665 0.335 0.000
F60.1 Schizoid personality disorder
0.665 0.335 0.000
F60.0 Paranoid personality disorder
0.665 0.335 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.664 0.336 0.000
I20-I25 Ischaemic heart diseases
0.664 0.336 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.661 0.338 0.000
C18.8 Overlapping lesion of colon
0.660 0.340 0.000
C18.5 Splenic flexure
0.660 0.340 0.000
C18.1 Appendix
0.660 0.340 0.000
Z40.8 Other prophylactic surgery
0.658 0.342 0.000
E10 Insulin-dependent diabetes mellitus
0.012 0.342 0.647
Z54 Convalescence
0.658 0.342 0.000
T65 Toxic effect of other and unspecified substances
0.655 0.345 0.000
T63 Toxic effect of contact with venomous animals
0.655 0.345 0.000
T62 Toxic effect of other noxious substances eaten as food
0.655 0.345 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.655 0.345 0.000
T60 Toxic effect of pesticides
0.655 0.345 0.000
T59 Toxic effect of other gases, fumes and vapours
0.655 0.345 0.000
T57 Toxic effect of other inorganic substances
0.655 0.345 0.000
T56 Toxic effect of metals
0.655 0.345 0.000
T54 Toxic effect of corrosive substances
0.655 0.345 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.655 0.345 0.000
T52 Toxic effect of organic solvents
0.655 0.345 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.655 0.345 0.000
T58 Toxic effect of carbon monoxide
0.655 0.345 0.000
T55 Toxic effect of soaps and detergents
0.655 0.345 0.000
J46 Status asthmaticus
0.000 0.345 0.655
Z03 Medical observation and evaluation for suspected diseases and conditions
0.654 0.346 0.000
G60 Hereditary and idiopathic neuropathy
0.654 0.346 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.654 0.346 0.000
R14 Flatulence and related conditions
0.654 0.346 0.000
L20-L30 Dermatitis and eczema
0.652 0.348 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.651 0.349 0.000
Q21.0 Ventricular septal defect
0.651 0.349 0.000
F33.8 Other recurrent depressive disorders
0.648 0.351 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.648 0.351 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.648 0.351 0.000
C21.0 Anus, unspecified
0.648 0.352 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.648 0.352 0.000
J34 Other disorders of nose and nasal sinuses
0.000 0.354 0.646
J30.2 Other seasonal allergic rhinitis
0.000 0.354 0.646
J30.0 Vasomotor rhinitis
0.000 0.354 0.646
F31.8 Other bipolar affective disorders
0.646 0.354 0.000
F31.7 Bipolar affective disorder, currently in remission
0.646 0.354 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.646 0.354 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.646 0.354 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.646 0.354 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.645 0.355 0.000
T51.9 Alcohol, unspecified
0.644 0.356 0.000
K82 Other diseases of gallbladder
0.644 0.356 0.000
E07.1 Dyshormogenetic goitre
0.000 0.356 0.643
E07.0 Hypersecretion of calcitonin
0.000 0.356 0.643
J31.2 Chronic pharyngitis
0.000 0.356 0.643
J31.1 Chronic nasopharyngitis
0.000 0.356 0.643
D46 Myelodysplastic syndromes
0.643 0.357 0.000
E10.9 Without complications
0.000 0.358 0.642
G45 Transient cerebral ischaemic attacks and related syndromes
0.642 0.358 0.000
R10.4 Other and unspecified abdominal pain
0.641 0.359 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.641 0.359 0.000
T38.9 Other and unspecified hormone antagonists
0.639 0.361 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.639 0.361 0.000
T38.7 Androgens and anabolic congeners
0.639 0.361 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.639 0.361 0.000
T38.5 Other oestrogens and progestogens
0.639 0.361 0.000
T38.4 Oral contraceptives
0.639 0.361 0.000
T38.2 Antithyroid drugs
0.639 0.361 0.000
T38.1 Thyroid hormones and substitutes
0.639 0.361 0.000
T38.0 Glucocorticoids and synthetic analogues
0.639 0.361 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.638 0.361 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.638 0.362 0.000
J01 Acute sinusitis
0.000 0.363 0.637
C15 Malignant neoplasm of oesophagus
0.637 0.363 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.364 0.636
Z42.9 Follow-up care involving plastic surgery, unspecified
0.635 0.365 0.000
Z42.8 Follow-up care involving plastic surgery of other body part
0.635 0.365 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.635 0.365 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.635 0.365 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.634 0.366 0.000
S37 Injury of urinary and pelvic organs
0.634 0.366 0.000
S36 Injury of intra-abdominal organs
0.634 0.366 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.634 0.366 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.634 0.366 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.634 0.366 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.633 0.367 0.000
R47-R49 Symptoms and signs involving speech and voice
0.633 0.367 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.632 0.368 0.000
S32.4 Fracture of acetabulum
0.632 0.368 0.000
S81 Open wound of lower leg
0.630 0.370 0.000
C17.0 Duodenum
0.629 0.371 0.000
I21 Acute myocardial infarction
0.628 0.372 0.000
Z12 Special screening examination for neoplasms
0.628 0.372 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.628 0.372 0.000
F42.9 Obsessive-compulsive disorder, unspecified
0.628 0.372 0.000
F45.9 Somatoform disorder, unspecified
0.627 0.373 0.000
F45.4 Persistent somatoform pain disorder
0.627 0.373 0.000
F45.3 Somatoform autonomic dysfunction
0.627 0.373 0.000
F45.2 Hypochondriacal disorder
0.627 0.373 0.000
F45.1 Undifferentiated somatoform disorder
0.627 0.373 0.000
F45.0 Somatisation disorder
0.627 0.373 0.000
G96 Other disorders of central nervous system
0.627 0.373 0.000
I21.4 Acute subendocardial myocardial infarction
0.626 0.374 0.000
K81 Cholecystitis
0.625 0.375 0.000
G61.8 Other inflammatory polyneuropathies
0.624 0.376 0.000
R23 Other skin changes
0.624 0.376 0.000
K70 Alcoholic liver disease
0.624 0.376 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.624 0.376 0.000
S40 Superficial injury of shoulder and upper arm
0.623 0.376 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.622 0.377 0.000
S92.0 Fracture of calcaneus
0.622 0.378 0.000
K83.1 Obstruction of bile duct
0.621 0.379 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.380 0.619
Q28 Other congenital malformations of circulatory system
0.619 0.381 0.000
Q27 Other congenital malformations of peripheral vascular system
0.619 0.381 0.000
Q26 Congenital malformations of great veins
0.619 0.381 0.000
Q25 Congenital malformations of great arteries
0.619 0.381 0.000
Q24 Other congenital malformations of heart
0.619 0.381 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.619 0.381 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.619 0.381 0.000
I24 Other acute ischaemic heart diseases
0.619 0.381 0.000
I05-I09 Chronic rheumatic heart diseases
0.619 0.381 0.000
C25 Malignant neoplasm of pancreas
0.618 0.382 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.617 0.383 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.617 0.383 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.616 0.384 0.000
G64 Other disorders of peripheral nervous system
0.616 0.384 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.616 0.384 0.000
Z03.8 Observation for other suspected diseases and conditions
0.616 0.384 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.384 0.616
C79.8 Secondary malignant neoplasm of other specified sites
0.616 0.384 0.000
I60-I69 Cerebrovascular diseases
0.615 0.385 0.000
K82.8 Other specified diseases of gallbladder
0.615 0.385 0.000
S14 Injury of nerves and spinal cord at neck level
0.614 0.385 0.000
M07.6 Other enteropathic arthropathies
0.614 0.385 0.001
M07.5 Arthropathy in ulcerative colitis
0.614 0.385 0.001
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.614 0.385 0.001
M07.2 Psoriatic spondylitis
0.614 0.385 0.001
M07.1 Arthritis mutilans
0.614 0.385 0.001
M07.0 Distal interphalangeal psoriatic arthropathy
0.614 0.385 0.001
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.614 0.386 0.000
C34.9 Bronchus or lung, unspecified
0.614 0.386 0.000
G30-G32 Other degenerative diseases of the nervous system
0.613 0.386 0.000
T50.8 Diagnostic agents
0.613 0.387 0.000
T50.7 Analeptics and opioid receptor antagonists
0.613 0.387 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.613 0.387 0.000
T50.5 Appetite depressants
0.613 0.387 0.000
T50.4 Drugs affecting uric acid metabolism
0.613 0.387 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.613 0.387 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.613 0.387 0.000
T50.1 Loop [high-ceiling] diuretics
0.613 0.387 0.000
T50.0 Mineralocorticoids and their antagonists
0.613 0.387 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.388 0.612
J80 Adult respiratory distress syndrome
0.000 0.388 0.612
K72 Hepatic failure, not elsewhere classified
0.611 0.389 0.000
Chapter I Certain infectious and parasitic diseases
0.611 0.389 0.000
T51.8 Other alcohols
0.611 0.389 0.000
T51.3 Fusel oil
0.611 0.389 0.000
T51.2 2-Propanol
0.611 0.389 0.000
T51.1 Methanol
0.611 0.389 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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