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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2516688
log Bayes Factor = 33.2915
Chromosome 6   position 30,364,524  (GRCh37) Explore rs2516688 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.025 0.975
E10 Insulin-dependent diabetes mellitus
0.000 0.028 0.972
E10.9 Without complications
0.000 0.030 0.970
E00-E07 Disorders of thyroid gland
0.000 0.045 0.955
E10-E14 Diabetes mellitus
0.000 0.048 0.952
E10.3 With ophthalmic complications
0.000 0.049 0.951
E10.2 With renal complications
0.000 0.053 0.947
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.053 0.947
K90 Intestinal malabsorption
0.000 0.105 0.895
E06 Thyroiditis
0.000 0.145 0.855
E10.4 With neurological complications
0.000 0.149 0.851
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.157 0.843
K90.9 Intestinal malabsorption, unspecified
0.000 0.168 0.832
E20-E35 Disorders of other endocrine glands
0.000 0.212 0.788
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.223 0.777
E14 Unspecified diabetes mellitus
0.000 0.227 0.773
E16 Other disorders of pancreatic internal secretion
0.000 0.232 0.768
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.246 0.754
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.257 0.742
E03.8 Other specified hypothyroidism
0.000 0.268 0.732
K90.8 Other intestinal malabsorption
0.000 0.269 0.731
E06.9 Thyroiditis, unspecified
0.000 0.271 0.729
E22 Hyperfunction of pituitary gland
0.000 0.275 0.725
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.291 0.709
E06.3 Autoimmune thyroiditis
0.000 0.293 0.707
E03.5 Myxoedema coma
0.000 0.301 0.699
E03.4 Atrophy of thyroid (acquired)
0.000 0.301 0.699
E03.3 Postinfectious hypothyroidism
0.000 0.301 0.699
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.302 0.698
E27 Other disorders of adrenal gland
0.000 0.309 0.691
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.315 0.684
E00 Congenital iodine-deficiency syndrome
0.000 0.315 0.684
E12 Malnutrition-related diabetes mellitus
0.000 0.317 0.682
E23 Hypofunction and other disorders of pituitary gland
0.000 0.320 0.680
E10.7 With multiple complications
0.000 0.321 0.678
E50-E64 Other nutritional deficiencies
0.000 0.322 0.678
E14.1 With ketoacidosis
0.000 0.327 0.673
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.333 0.667
E13 Other specified diabetes mellitus
0.000 0.338 0.662
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.345 0.655
E03.1 Congenital hypothyroidism without goitre
0.000 0.355 0.645
K90.3 Pancreatic steatorrhoea
0.000 0.358 0.642
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.358 0.642
K90.1 Tropical sprue
0.000 0.358 0.642
E27.1 Primary adrenocortical insufficiency
0.000 0.362 0.638
E22.1 Hyperprolactinaemia
0.000 0.366 0.634
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.366 0.634
E06.1 Subacute thyroiditis
0.000 0.370 0.630
E14.2 Withrenal complications
0.000 0.376 0.624
E05.9 Thyrotoxicosis, unspecified
0.000 0.378 0.622
E16.1 Other hypoglycaemia
0.000 0.384 0.616
E14.8 With unspecified complications
0.000 0.385 0.615
E23.2 Diabetes insipidus
0.000 0.387 0.613
E06.5 Other chronic thyroiditis
0.000 0.387 0.613
E06.4 Drug-induced thyroiditis
0.000 0.387 0.613
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.387 0.613
E06.0 Acute thyroiditis
0.000 0.387 0.613
E15 Nondiabetic hypoglycaemic coma
0.000 0.396 0.604
E14.4 With neurological complications
0.000 0.408 0.592
E10.0 With coma
0.000 0.408 0.592
E14.6 With other specified complications
0.000 0.412 0.588
E55 Vitamin D deficiency
0.000 0.416 0.584
E27.2 Addisonian crisis
0.000 0.424 0.576
E10.1 With ketoacidosis
0.000 0.427 0.573
E21.0 Primary hyperparathyroidism
0.000 0.428 0.572
E14.3 With ophthalmic complications
0.000 0.430 0.570
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.435 0.565
E32 Diseases of thymus
0.000 0.435 0.565
E31 Polyglandular dysfunction
0.000 0.435 0.565
E30 Disorders of puberty, not elsewhere classified
0.000 0.435 0.565
E10.5 With peripheral circulatory complications
0.000 0.436 0.564
E24 Cushing's syndrome
0.000 0.439 0.561
E10.6 With other specified complications
0.000 0.443 0.557
E14.7 With multiple complications
0.000 0.446 0.554
E14.0 With coma
0.000 0.446 0.554
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.449 0.551
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.449 0.551
E16.4 Abnormal secretion of gastrin
0.000 0.449 0.551
E16.3 Increased secretion of glucagon
0.000 0.449 0.551
E10.8 With unspecified complications
0.000 0.455 0.545
E26 Hyperaldosteronism
0.000 0.460 0.539
E23.0 Hypopituitarism
0.000 0.464 0.536
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.467 0.533
E58 Dietary calcium deficiency
0.000 0.467 0.533
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.480 0.520
E22.8 Other hyperfunction of pituitary gland
0.000 0.480 0.520
E40-E46 Malnutrition
0.000 0.480 0.519
E51 Thiamine deficiency
0.000 0.482 0.518
E55.9 Vitamin D deficiency, unspecified
0.000 0.483 0.517
E14.5 With peripheral circulatory complications
0.000 0.493 0.507
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.496 0.504
E05.5 Thyroid crisis or storm
0.000 0.499 0.501
E05.4 Thyrotoxicosis factitia
0.000 0.499 0.501
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.499 0.501
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.499 0.501
E13.3 With ophthalmic complications
0.000 0.500 0.500
E25 Adrenogenital disorders
0.000 0.502 0.498
E27.5 Adrenomedullary hyperfunction
0.000 0.504 0.495
E27.0 Other adrenocortical overactivity
0.000 0.504 0.495
E27.9 Disorder of adrenal gland, unspecified
0.000 0.508 0.492
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.509 0.491
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.509 0.491
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.509 0.491
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.509 0.491
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.509 0.491
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.509 0.491
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.509 0.491
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.509 0.491
E16.2 Hypoglycaemia, unspecified
0.000 0.510 0.490
E12.9 Without complications
0.000 0.510 0.489
E12.8 With unspecified complications
0.000 0.510 0.489
E12.7 With multiple complications
0.000 0.510 0.489
E12.6 With other specified complications
0.000 0.510 0.489
E12.5 With peripheral circulatory complications
0.000 0.510 0.489
E12.4 With neurological complications
0.000 0.510 0.489
E12.3 With ophthalmic complications
0.000 0.510 0.489
E12.2 With renal complications
0.000 0.510 0.489
E12.1 With ketoacidosis
0.000 0.510 0.489
E12.0 With coma
0.000 0.510 0.489
E20 Hypoparathyroidism
0.000 0.512 0.488
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.512 0.488
E23.1 Drug-induced hypopituitarism
0.000 0.512 0.488
E23.7 Disorder of pituitary gland, unspecified
0.000 0.513 0.487
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.514 0.486
E63 Other nutritional deficiencies
0.000 0.514 0.486
E50 Vitamin A deficiency
0.000 0.514 0.486
E60 Dietary zinc deficiency
0.000 0.514 0.486
E59 Dietary selenium deficiency
0.000 0.514 0.486
E52 Niacin deficiency [pellagra]
0.000 0.514 0.486
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.523 0.477
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.524 0.476
E13.8 With unspecified complications
0.000 0.525 0.474
E13.7 With multiple complications
0.000 0.525 0.474
E13.6 With other specified complications
0.000 0.525 0.474
E13.5 With peripheral circulatory complications
0.000 0.525 0.474
E13.4 With neurological complications
0.000 0.525 0.474
E13.2 With renal complications
0.000 0.525 0.474
E13.1 With ketoacidosis
0.000 0.525 0.474
E13.0 With coma
0.000 0.525 0.474
E54 Ascorbic acid deficiency
0.000 0.535 0.465
E56 Other vitamin deficiencies
0.000 0.541 0.459
E28 Ovarian dysfunction
0.000 0.556 0.444
E21.2 Other hyperparathyroidism
0.000 0.560 0.440
E05.8 Other thyrotoxicosis
0.000 0.574 0.426
E13.9 Without complications
0.000 0.579 0.421
E55.0 Rickets, active
0.000 0.581 0.419
E24.8 Other Cushing's syndrome
0.000 0.582 0.418
E21.4 Other specified disorders of parathyroid gland
0.000 0.589 0.411
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.591 0.409
E07 Other disorders of thyroid
0.000 0.594 0.406
E30.9 Disorder of puberty, unspecified
0.000 0.594 0.405
E30.8 Other disorders of puberty
0.000 0.594 0.405
E30.1 Precocious puberty
0.000 0.594 0.405
E30.0 Delayed puberty
0.000 0.594 0.405
E31.9 Polyglandular dysfunction, unspecified
0.000 0.594 0.405
E31.8 Other polyglandular dysfunction
0.000 0.594 0.405
E31.1 Polyglandular hyperfunction
0.000 0.594 0.405
E31.0 Autoimmune polyglandular failure
0.000 0.594 0.405
E32.9 Disease of thymus, unspecified
0.000 0.594 0.405
E32.8 Other diseases of thymus
0.000 0.594 0.405
E32.1 Abscess of thymus
0.000 0.594 0.405
E32.0 Persistent hyperplasia of thymus
0.000 0.594 0.405
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.594 0.405
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.594 0.405
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.594 0.405
E24.0 Pituitary-dependent Cushing's disease
0.000 0.595 0.405
E51.2 Wernicke's encephalopathy
0.000 0.596 0.404
E29 Testicular dysfunction
0.000 0.597 0.402
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.597 0.402
E24.3 Ectopic ACTH syndrome
0.000 0.597 0.402
E24.1 Nelson's syndrome
0.000 0.597 0.402
E24.9 Cushing's syndrome, unspecified
0.000 0.601 0.399
E26.9 Hyperaldosteronism, unspecified
0.000 0.609 0.391
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.612 0.388
E26.8 Other hyperaldosteronism
0.000 0.613 0.387
E26.1 Secondary hyperaldosteronism
0.000 0.613 0.387
E23.6 Other disorders of pituitary gland
0.000 0.617 0.383
E61 Deficiency of other nutrient elements
0.000 0.617 0.383
E24.2 Drug-induced Cushing's syndrome
0.000 0.618 0.382
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.627 0.372
E45 Retarded development following protein-energy malnutrition
0.000 0.627 0.372
E43 Unspecified severe protein-energy malnutrition
0.000 0.627 0.372
E42 Marasmic kwashiorkor
0.000 0.627 0.372
E41 Nutritional marasmus
0.000 0.627 0.372
E40 Kwashiorkor
0.000 0.627 0.372
E51.9 Thiamine deficiency, unspecified
0.000 0.628 0.372
E51.8 Other manifestations of thiamine deficiency
0.000 0.628 0.372
E51.1 Beriberi
0.000 0.628 0.372
E22.0 Acromegaly and pituitary gigantism
0.000 0.632 0.368
E25.9 Adrenogenital disorder, unspecified
0.000 0.642 0.357
E25.8 Other adrenogenital disorders
0.000 0.642 0.357
E26.0 Primary hyperaldosteronism
0.000 0.644 0.356
E53 Deficiency of other B group vitamins
0.000 0.644 0.356
E20.8 Other hypoparathyroidism
0.000 0.650 0.350
E20.1 Pseudohypoparathyroidism
0.000 0.650 0.350
E20.0 Idiopathic hypoparathyroidism
0.000 0.650 0.350
E50.9 Vitamin A deficiency, unspecified
0.000 0.651 0.348
E50.8 Other manifestations of vitamin A deficiency
0.000 0.651 0.348
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.651 0.348
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.651 0.348
E50.5 Vitamin A deficiency with night blindness
0.000 0.651 0.348
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.651 0.348
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.651 0.348
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.651 0.348
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.651 0.348
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.651 0.348
E63.9 Nutritional deficiency, unspecified
0.000 0.651 0.348
E63.8 Other specified nutritional deficiencies
0.000 0.651 0.348
E63.1 Imbalance of constituents of food intake
0.000 0.651 0.348
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.651 0.348
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.651 0.348
E64.8 Sequelae of other nutritional deficiencies
0.000 0.651 0.348
E64.3 Sequelae of rickets
0.000 0.651 0.348
E64.2 Sequelae of vitamin C deficiency
0.000 0.651 0.348
E64.1 Sequelae of vitamin A deficiency
0.000 0.651 0.348
E64.0 Sequelae of protein-energy malnutrition
0.000 0.651 0.348
E56.9 Vitamin deficiency, unspecified
0.000 0.671 0.329
E56.8 Deficiency of other vitamins
0.000 0.671 0.329
E56.0 Deficiency of vitamin E
0.000 0.671 0.329
E27.8 Other specified disorders of adrenal gland
0.000 0.675 0.325
E28.9 Ovarian dysfunction, unspecified
0.000 0.682 0.318
E28.8 Other ovarian dysfunction
0.000 0.682 0.318
E28.1 Androgen excess
0.000 0.682 0.318
E28.0 Oestrogen excess
0.000 0.682 0.318
E56.1 Deficiency of vitamin K
0.000 0.698 0.302
E07.1 Dyshormogenetic goitre
0.000 0.709 0.291
E07.0 Hypersecretion of calcitonin
0.000 0.709 0.291
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.709 0.290
E29.8 Other testicular dysfunction
0.000 0.711 0.289
E29.0 Testicular hyperfunction
0.000 0.711 0.289
E29.9 Testicular dysfunction, unspecified
0.000 0.721 0.279
E34 Other endocrine disorders
0.001 0.724 0.275
E28.3 Primary ovarian failure
0.000 0.725 0.275
E61.9 Deficiency of nutrient element, unspecified
0.000 0.725 0.274
E61.8 Deficiency of other specified nutrient elements
0.000 0.725 0.274
E61.7 Deficiency of multiple nutrient elements
0.000 0.725 0.274
E61.6 Vanadium deficiency
0.000 0.725 0.274
E61.5 Molybdenum deficiency
0.000 0.725 0.274
E61.4 Chromium deficiency
0.000 0.725 0.274
E61.3 Manganese deficiency
0.000 0.725 0.274
E61.0 Copper deficiency
0.000 0.725 0.274
E20.9 Hypoparathyroidism, unspecified
0.000 0.727 0.273
E44.1 Mild protein-energy malnutrition
0.000 0.733 0.267
E44.0 Moderate protein-energy malnutrition
0.000 0.733 0.267
E07.8 Other specified disorders of thyroid
0.000 0.736 0.264
E21.3 Hyperparathyroidism, unspecified
0.000 0.736 0.264
E28.2 Polycystic ovarian syndrome
0.000 0.739 0.261
E61.2 Magnesium deficiency
0.000 0.742 0.258
E53.1 Pyridoxine deficiency
0.000 0.744 0.255
E53.0 Riboflavin deficiency
0.000 0.744 0.255
E53.9 Vitamin B deficiency, unspecified
0.000 0.765 0.234
E65-E68 Obesity and other hyperalimentation
0.001 0.783 0.216
E46 Unspecified protein-energy malnutrition
0.000 0.787 0.213
E61.1 Iron deficiency
0.000 0.800 0.199
E34.5 Androgen resistance syndrome
0.001 0.802 0.197
E34.4 Constitutional tall stature
0.001 0.802 0.197
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.802 0.197
E34.1 Other hypersecretion of intestinal hormones
0.001 0.802 0.197
E34.3 Short stature, not elsewhere classified
0.001 0.811 0.188
E34.8 Other specified endocrine disorders
0.001 0.816 0.183
E53.8 Deficiency of other specified B group vitamins
0.000 0.835 0.165
E34.0 Carcinoid syndrome
0.001 0.839 0.160
E67 Other hyperalimentation
0.001 0.844 0.155
E68 Sequelae of hyperalimentation
0.001 0.844 0.155
E29.1 Testicular hypofunction
0.000 0.852 0.147
E04 Other non-toxic goitre
0.000 0.873 0.127
E67.8 Other specified hyperalimentation
0.001 0.888 0.111
E67.3 Hypervitaminosis D
0.001 0.888 0.111
E67.2 Megavitamin-B6 syndrome
0.001 0.888 0.111
E67.1 Hypercarotenaemia
0.001 0.888 0.111
E67.0 Hypervitaminosis A
0.001 0.888 0.111
G25.8 Other specified extrapyramidal and movement disorders
0.110 0.890 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.101 0.899 0.000
G25 Other extrapyramidal and movement disorders
0.098 0.902 0.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.908 0.092
G20-G26 Extrapyramidal and movement disorders
0.092 0.908 0.000
E04.8 Other specified non-toxic goitre
0.000 0.908 0.091
G24 Dystonia
0.089 0.911 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.911 0.088
E34.9 Endocrine disorder, unspecified
0.002 0.911 0.087
E04.0 Non-toxic diffuse goitre
0.000 0.914 0.086
G25.9 Extrapyramidal and movement disorder, unspecified
0.082 0.918 0.000
G21 Secondary Parkinsonism
0.082 0.918 0.000
G24.9 Dystonia, unspecified
0.081 0.919 0.000
G24.3 Spasmodic torticollis
0.077 0.923 0.000
G25.1 Drug-induced tremor
0.075 0.924 0.000
G25.5 Other chorea
0.075 0.925 0.000
G24.8 Other dystonia
0.073 0.927 0.000
G23 Other degenerative diseases of basal ganglia
0.072 0.928 0.000
G25.6 Drug-induced tics and other tics of organic origin
0.070 0.930 0.000
G25.4 Drug-induced chorea
0.070 0.930 0.000
G21.9 Secondary Parkinsonism, unspecified
0.069 0.930 0.000
G24.1 Idiopathic familial dystonia
0.067 0.933 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.933 0.067
G21.1 Other drug-induced secondary Parkinsonism
0.066 0.933 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.066 0.934 0.000
G22 Parkinsonism in diseases classified elsewhere
0.066 0.934 0.000
G24.0 Drug-induced dystonia
0.065 0.935 0.000
G24.4 Idiopathic orofacial dystonia
0.064 0.936 0.000
G24.2 Idiopathic nonfamilial dystonia
0.064 0.936 0.000
G24.5 Blepharospasm
0.061 0.938 0.000
G21.4 Vascular parkinsonism
0.061 0.939 0.000
G25.0 Essential tremor
0.061 0.939 0.000
G20 Parkinson's disease
0.059 0.941 0.000
G21.8 Other secondary Parkinsonism
0.059 0.941 0.000
G21.3 Postencephalitic Parkinsonism
0.059 0.941 0.000
G21.2 Secondary Parkinsonism due to other external agents
0.059 0.941 0.000
G21.0 Malignant neuroleptic syndrome
0.059 0.941 0.000
G25.3 Myoclonus
0.057 0.943 0.000
G23.8 Other specified degenerative diseases of basal ganglia
0.056 0.944 0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]
0.054 0.945 0.000
K90-K93 Other diseases of the digestive system
0.000 0.946 0.054
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.053 0.947 0.000
G23.9 Degenerative disease of basal ganglia, unspecified
0.052 0.948 0.000
G23.3 Multiple system atrophy, cerebellar type
0.052 0.948 0.000
G23.2 Striatonigral degeneration
0.052 0.948 0.000
G23.0 Hallervorden-Spatz disease
0.052 0.948 0.000
H26.9 Cataract, unspecified
0.000 0.949 0.051
G25.2 Other specified forms of tremor
0.048 0.952 0.000
E83 Disorders of mineral metabolism
0.026 0.952 0.022
E65 Localised adiposity
0.003 0.954 0.043
E14.9 Without complications
0.000 0.958 0.042
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.961 0.039
E83.8 Other disorders of mineral metabolism
0.019 0.965 0.016
E83.2 Disorders of zinc metabolism
0.019 0.965 0.016
E83.0 Disorders of copper metabolism
0.019 0.965 0.016
E83.9 Disorder of mineral metabolism, unspecified
0.018 0.966 0.016
E66 Obesity
0.000 0.969 0.031
K81.0 Acute cholecystitis
0.030 0.970 0.000
E70-E90 Metabolic disorders
0.001 0.971 0.028
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.972 0.028
K93.1 Megacolon in Chagas' disease
0.000 0.972 0.028
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.972 0.028
E83.3 Disorders of phosphorus metabolism
0.006 0.974 0.019
E86 Volume depletion
0.000 0.976 0.024
E66.0 Obesity due to excess calories
0.000 0.977 0.023
E66.1 Drug-induced obesity
0.000 0.977 0.022
E83.4 Disorders of magnesium metabolism
0.003 0.978 0.019
E11 Non-insulin-dependent diabetes mellitus
0.000 0.978 0.022
N05.9 Unspecified
0.000 0.978 0.022
E04.1 Non-toxic single thyroid nodule
0.000 0.978 0.022
E04.9 Non-toxic goitre, unspecified
0.000 0.979 0.021
E70 Disorders of aromatic amino-acid metabolism
0.001 0.979 0.021
E77 Disorders of glycoprotein metabolism
0.001 0.979 0.020
E76 Disorders of glycosaminoglycan metabolism
0.001 0.979 0.020
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.979 0.020
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.979 0.020
E72 Other disorders of amino-acid metabolism
0.001 0.979 0.020
E79 Disorders of purine and pyrimidine metabolism
0.001 0.979 0.020
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.979 0.020
E74 Other disorders of carbohydrate metabolism
0.001 0.980 0.020
E84 Cystic fibrosis
0.001 0.980 0.019
N05 Unspecified nephritic syndrome
0.000 0.981 0.019
E11.6 With other specified complications
0.000 0.981 0.019
H26 Other cataract
0.000 0.981 0.019
M35 Other systemic involvement of connective tissue
0.000 0.982 0.018
E73 Lactose intolerance
0.001 0.982 0.017
N05.2 Diffuse membranous glomerulonephritis
0.000 0.982 0.018
N05.8 Other
0.000 0.982 0.018
I83 Varicose veins of lower extremities
0.016 0.984 0.000
E11.7 With multiple complications
0.000 0.984 0.016
M35.2 Behcet's disease
0.000 0.984 0.016
E70.3 Albinism
0.001 0.984 0.015
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.001 0.985 0.015
E70.8 Other disorders of aromatic amino-acid metabolism
0.001 0.985 0.015
E70.2 Disorders of tyrosine metabolism
0.001 0.985 0.015
E70.1 Other hyperphenylalaninaemias
0.001 0.985 0.015
E70.0 Classical phenylketonuria
0.001 0.985 0.015
E71.3 Disorders of fatty-acid metabolism
0.001 0.985 0.015
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.985 0.015
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.985 0.015
E71.0 Maple-syrup-urine disease
0.001 0.985 0.015
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.985 0.015
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.985 0.015
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.985 0.015
E76.2 Other mucopolysaccharidoses
0.001 0.985 0.015
E76.1 Mucopolysaccharidosis, type II
0.001 0.985 0.015
E76.0 Mucopolysaccharidosis, type I
0.001 0.985 0.015
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.985 0.015
E77.8 Other disorders of glycoprotein metabolism
0.001 0.985 0.015
E77.1 Defects in glycoprotein degradation
0.001 0.985 0.015
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.985 0.015
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.985 0.015
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.985 0.015
E72.5 Disorders of glycine metabolism
0.001 0.985 0.015
E72.4 Disorders of ornithine metabolism
0.001 0.985 0.015
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.985 0.015
E72.2 Disorders of urea cycle metabolism
0.001 0.985 0.015
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.985 0.015
E72.0 Disorders of amino-acid transport
0.001 0.985 0.015
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.001 0.985 0.015
E79.8 Other disorders of purine and pyrimidine metabolism
0.001 0.985 0.015
E79.1 Lesch-Nyhan syndrome
0.001 0.985 0.015
E75.6 Lipid storage disorder, unspecified
0.001 0.985 0.015
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.985 0.015
E75.3 Sphingolipidosis, unspecified
0.001 0.985 0.015
E75.1 Other gangliosidosis
0.001 0.985 0.015
E75.0 GM2 gangliosidosis
0.001 0.985 0.015
N05.1 Focal and segmental glomerular lesions
0.000 0.985 0.015
H26.3 Drug-induced cataract
0.000 0.985 0.015
E75.2 Other sphingolipidosis
0.001 0.985 0.015
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.985 0.015
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.985 0.014
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.985 0.014
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.985 0.014
E74.2 Disorders of galactose metabolism
0.001 0.985 0.014
E74.1 Disorders of fructose metabolism
0.001 0.985 0.014
E74.0 Glycogen storage disease
0.001 0.985 0.014
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.985 0.014
E75.5 Other lipid storage disorders
0.001 0.985 0.014
E85 Amyloidosis
0.001 0.985 0.014
H26.8 Other specified cataract
0.000 0.985 0.015
E11.1 With ketoacidosis
0.000 0.985 0.015
E84.8 Cystic fibrosis with other manifestations
0.001 0.985 0.014
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.985 0.014
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.985 0.014
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.986 0.014
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.986 0.014
H26.1 Traumatic cataract
0.000 0.986 0.014
N05.6 Dense deposit disease
0.000 0.986 0.014
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.986 0.014
N05.0 Minor glomerular abnormality
0.000 0.986 0.014
E11.0 With coma
0.000 0.986 0.014
E84.9 Cystic fibrosis, unspecified
0.001 0.986 0.013
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.987 0.013
E11.2 With renal complications
0.000 0.987 0.013
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.987 0.013
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.987 0.013
M35.5 Multifocal fibrosclerosis
0.000 0.987 0.013
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.987 0.013
E73.8 Other lactose intolerance
0.001 0.987 0.013
E73.1 Secondary lactase deficiency
0.001 0.987 0.013
E73.0 Congenital lactase deficiency
0.001 0.987 0.013
E66.2 Extreme obesity with alveolar hypoventilation
0.001 0.987 0.012
M35.8 Other specified systemic involvement of connective tissue
0.000 0.987 0.013
E11.8 With unspecified complications
0.000 0.987 0.013
G90.2 Horner's syndrome
0.000 0.987 0.013
I83.0 Varicose veins of lower extremities with ulcer
0.013 0.987 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.988 0.012
N05.7 Diffuse crescentic glomerulonephritis
0.000 0.988 0.012
G90 Disorders of autonomic nervous system
0.000 0.988 0.012
G90.0 Idiopathic peripheral autonomic neuropathy
0.000 0.988 0.012
H26.2 Complicated cataract
0.000 0.988 0.012
E89.3 Postprocedural hypopituitarism
0.000 0.988 0.012
M35.1 Other overlap syndromes
0.000 0.988 0.012
M35.7 Hypermobility syndrome
0.000 0.988 0.011
G90.3 Multisystem degeneration
0.000 0.989 0.011
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.989 0.011
E88 Other metabolic disorders
0.001 0.989 0.010
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.989 0.010
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.989 0.010
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.989 0.010
E66.8 Other obesity
0.000 0.989 0.011
E85.3 Secondary systemic amyloidosis
0.001 0.989 0.010
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.010 0.989 0.000
G57.6 Lesion of plantar nerve
0.011 0.989 0.000
E85.9 Amyloidosis, unspecified
0.001 0.989 0.010
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.990 0.010
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.990 0.010
E89.5 Postprocedural testicular hypofunction
0.000 0.990 0.010
X23.9 Unspecified place
0.000 0.990 0.010
E85.8 Other amyloidosis
0.001 0.990 0.010
E73.9 Lactose intolerance, unspecified
0.001 0.990 0.010
G90.9 Disorder of autonomic nervous system, unspecified
0.000 0.990 0.010
H27 Other disorders of lens
0.000 0.990 0.010
E89.2 Postprocedural hypoparathyroidism
0.000 0.990 0.010
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.990 0.010
E80.2 Other porphyria
0.000 0.990 0.009
K40 Inguinal hernia
0.010 0.990 0.000
E89.4 Postprocedural ovarian failure
0.000 0.990 0.009
E89.1 Postprocedural hypoinsulinaemia
0.000 0.990 0.009
G90.8 Other disorders of autonomic nervous system
0.000 0.991 0.009
H27.0 Aphakia
0.000 0.991 0.009
H25-H28 Disorders of lens
0.000 0.991 0.009
H27.8 Other specified disorders of lens
0.000 0.991 0.009
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.991 0.009
E80.5 Crigler-Najjar syndrome
0.001 0.991 0.009
E80.3 Defects of catalase and peroxydase
0.001 0.991 0.009
E80.0 Hereditary erythropoietic porphyria
0.001 0.991 0.009
E80.6 Other disorders of bilirubin metabolism
0.001 0.991 0.009
E83.5 Disorders of calcium metabolism
0.003 0.991 0.006
G90.4 Autonomic dysreflexia
0.000 0.991 0.009
G90.1 Familial dysautonomia [Riley-Day]
0.000 0.991 0.009
I83.1 Varicose veins of lower extremities with inflammation
0.009 0.991 0.000
I47.2 Ventricular tachycardia
0.000 0.991 0.009
H26.4 After-cataract
0.000 0.991 0.009
E88.8 Other specified metabolic disorders
0.001 0.991 0.008
E88.2 Lipomatosis, not elsewhere classified
0.001 0.991 0.008
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.992 0.008
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.008 0.992 0.000
E88.3 Tumour lysis syndrome
0.001 0.992 0.007
E88.9 Metabolic disorder, unspecified
0.001 0.992 0.007
E11.5 With peripheral circulatory complications
0.000 0.992 0.008
E80.1 Porphyria cutanea tarda
0.001 0.993 0.007
H26.0 Infantile, juvenile and presenile cataract
0.000 0.993 0.007
X23 Contact with hornets, wasps and bees
0.000 0.993 0.007
H27.9 Disorder of lens, unspecified
0.000 0.993 0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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