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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2517453
log Bayes Factor = 137.984
Chromosome 6   position 31,060,115  (GRCh37) Explore rs2517453 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40 Psoriasis
0.999 0.001 0.000
E07 Other disorders of thyroid
0.000 0.002 0.998
E07.9 Disorder of thyroid, unspecified
0.000 0.003 0.997
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.006 0.994
L40.5 Arthropathic psoriasis
0.987 0.013 0.000
L40.0 Psoriasis vulgaris
0.984 0.016 0.000
E83.1 Disorders of iron metabolism
0.971 0.029 0.000
C61 Malignant neoplasm of prostate
0.924 0.076 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.151 0.849
L40.4 Guttate psoriasis
0.817 0.183 0.000
E03.8 Other specified hypothyroidism
0.000 0.196 0.804
K90 Intestinal malabsorption
0.000 0.205 0.795
L40.3 Pustulosis palmaris et plantaris
0.790 0.210 0.000
E06 Thyroiditis
0.000 0.239 0.761
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.241 0.759
L40.1 Generalised pustular psoriasis
0.737 0.263 0.000
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.716 0.284 0.000
E07.1 Dyshormogenetic goitre
0.000 0.284 0.716
E07.0 Hypersecretion of calcitonin
0.000 0.284 0.716
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.291 0.708
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.292 0.708
E07.8 Other specified disorders of thyroid
0.000 0.298 0.702
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.305 0.695
K90.9 Intestinal malabsorption, unspecified
0.000 0.336 0.664
E05.8 Other thyrotoxicosis
0.000 0.338 0.662
L40.8 Other psoriasis
0.647 0.353 0.000
E06.3 Autoimmune thyroiditis
0.000 0.365 0.635
E06.5 Other chronic thyroiditis
0.000 0.390 0.610
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.391 0.609
E03.1 Congenital hypothyroidism without goitre
0.000 0.397 0.602
K90.8 Other intestinal malabsorption
0.000 0.402 0.598
E10.9 Without complications
0.000 0.408 0.592
E10 Insulin-dependent diabetes mellitus
0.000 0.422 0.578
M35.0 Sicca syndrome [Sjogren]
0.000 0.422 0.578
K90.3 Pancreatic steatorrhoea
0.000 0.430 0.570
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.430 0.570
K90.1 Tropical sprue
0.000 0.430 0.570
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.441 0.559
E10-E14 Diabetes mellitus
0.000 0.442 0.558
E10.3 With ophthalmic complications
0.000 0.450 0.550
E06.4 Drug-induced thyroiditis
0.000 0.454 0.545
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.454 0.545
E06.0 Acute thyroiditis
0.000 0.454 0.545
E06.1 Subacute thyroiditis
0.000 0.469 0.531
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E10.2 With renal complications
0.000 0.503 0.497
E10.0 With coma
0.000 0.577 0.423
E10.7 With multiple complications
0.000 0.583 0.417
E20-E35 Disorders of other endocrine glands
0.000 0.591 0.409
E14 Unspecified diabetes mellitus
0.000 0.594 0.406
E12 Malnutrition-related diabetes mellitus
0.000 0.600 0.400
E10.4 With neurological complications
0.000 0.602 0.398
E28 Ovarian dysfunction
0.000 0.606 0.394
E40-E46 Malnutrition
0.000 0.626 0.374
E28.3 Primary ovarian failure
0.000 0.627 0.373
E06.9 Thyroiditis, unspecified
0.000 0.631 0.369
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.632 0.368
E14.3 With ophthalmic complications
0.000 0.637 0.363
E10.8 With unspecified complications
0.000 0.649 0.351
E23 Hypofunction and other disorders of pituitary gland
0.000 0.654 0.346
E13 Other specified diabetes mellitus
0.000 0.655 0.345
E10.6 With other specified complications
0.000 0.657 0.343
E28.2 Polycystic ovarian syndrome
0.000 0.664 0.336
E24 Cushing's syndrome
0.000 0.665 0.335
E14.5 With peripheral circulatory complications
0.000 0.678 0.322
C60-C63 Malignant neoplasms of male genital organs
0.318 0.682 0.000
E23.2 Diabetes insipidus
0.000 0.684 0.316
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.688 0.312
E10.1 With ketoacidosis
0.000 0.693 0.307
E24.2 Drug-induced Cushing's syndrome
0.000 0.702 0.298
E14.1 With ketoacidosis
0.000 0.702 0.298
E14.8 With unspecified complications
0.000 0.702 0.297
E31 Polyglandular dysfunction
0.000 0.704 0.296
E10.5 With peripheral circulatory complications
0.000 0.706 0.294
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.707 0.293
E32 Diseases of thymus
0.000 0.707 0.293
E30 Disorders of puberty, not elsewhere classified
0.000 0.707 0.293
E14.7 With multiple complications
0.000 0.709 0.291
E14.0 With coma
0.000 0.709 0.291
E14.6 With other specified complications
0.000 0.712 0.287
E12.9 Without complications
0.000 0.713 0.287
E12.8 With unspecified complications
0.000 0.713 0.287
E12.7 With multiple complications
0.000 0.713 0.287
E12.6 With other specified complications
0.000 0.713 0.287
E12.5 With peripheral circulatory complications
0.000 0.713 0.287
E12.4 With neurological complications
0.000 0.713 0.287
E12.3 With ophthalmic complications
0.000 0.713 0.287
E12.2 With renal complications
0.000 0.713 0.287
E12.1 With ketoacidosis
0.000 0.713 0.287
E12.0 With coma
0.000 0.713 0.287
E28.9 Ovarian dysfunction, unspecified
0.000 0.717 0.282
E28.8 Other ovarian dysfunction
0.000 0.717 0.282
E28.1 Androgen excess
0.000 0.717 0.282
E28.0 Oestrogen excess
0.000 0.717 0.282
E14.2 Withrenal complications
0.000 0.721 0.279
E21.3 Hyperparathyroidism, unspecified
0.000 0.722 0.278
E23.7 Disorder of pituitary gland, unspecified
0.000 0.730 0.270
E23.6 Other disorders of pituitary gland
0.000 0.730 0.270
E14.4 With neurological complications
0.000 0.731 0.269
E13.3 With ophthalmic complications
0.000 0.731 0.269
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.732 0.268
E45 Retarded development following protein-energy malnutrition
0.000 0.732 0.268
E43 Unspecified severe protein-energy malnutrition
0.000 0.732 0.268
E42 Marasmic kwashiorkor
0.000 0.732 0.268
E41 Nutritional marasmus
0.000 0.732 0.268
E40 Kwashiorkor
0.000 0.732 0.268
E15 Nondiabetic hypoglycaemic coma
0.000 0.736 0.264
E26 Hyperaldosteronism
0.000 0.738 0.262
E20 Hypoparathyroidism
0.000 0.739 0.261
E25 Adrenogenital disorders
0.000 0.745 0.255
L40-L45 Papulosquamous disorders
0.253 0.747 0.000
E50-E64 Other nutritional deficiencies
0.000 0.748 0.252
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.752 0.248
E23.1 Drug-induced hypopituitarism
0.000 0.752 0.248
E13.8 With unspecified complications
0.000 0.752 0.248
E13.7 With multiple complications
0.000 0.752 0.248
E13.6 With other specified complications
0.000 0.752 0.248
E13.5 With peripheral circulatory complications
0.000 0.752 0.248
E13.4 With neurological complications
0.000 0.752 0.248
E13.2 With renal complications
0.000 0.752 0.248
E13.1 With ketoacidosis
0.000 0.752 0.248
E13.0 With coma
0.000 0.752 0.248
C60 Malignant neoplasm of penis
0.247 0.752 0.000
M35 Other systemic involvement of connective tissue
0.000 0.755 0.245
E46 Unspecified protein-energy malnutrition
0.000 0.759 0.241
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.759 0.241
E24.3 Ectopic ACTH syndrome
0.000 0.759 0.241
E24.1 Nelson's syndrome
0.000 0.759 0.241
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.759 0.240
E29 Testicular dysfunction
0.000 0.761 0.239
E24.0 Pituitary-dependent Cushing's disease
0.000 0.762 0.237
E24.8 Other Cushing's syndrome
0.000 0.765 0.235
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.768 0.231
E16 Other disorders of pancreatic internal secretion
0.000 0.769 0.231
E21.2 Other hyperparathyroidism
0.000 0.774 0.226
C63 Malignant neoplasm of other and unspecified male genital organs
0.220 0.780 0.000
E31.0 Autoimmune polyglandular failure
0.000 0.785 0.215
E31.9 Polyglandular dysfunction, unspecified
0.000 0.788 0.212
E31.8 Other polyglandular dysfunction
0.000 0.788 0.212
E31.1 Polyglandular hyperfunction
0.000 0.788 0.212
E24.9 Cushing's syndrome, unspecified
0.000 0.788 0.212
E30.9 Disorder of puberty, unspecified
0.000 0.789 0.210
E30.8 Other disorders of puberty
0.000 0.789 0.210
E30.1 Precocious puberty
0.000 0.789 0.210
E30.0 Delayed puberty
0.000 0.789 0.210
E32.9 Disease of thymus, unspecified
0.000 0.789 0.210
E32.8 Other diseases of thymus
0.000 0.789 0.210
E32.1 Abscess of thymus
0.000 0.789 0.210
E32.0 Persistent hyperplasia of thymus
0.000 0.789 0.210
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.789 0.210
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.789 0.210
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.789 0.210
E21.4 Other specified disorders of parathyroid gland
0.000 0.791 0.209
M35.7 Hypermobility syndrome
0.000 0.796 0.204
L41 Parapsoriasis
0.202 0.798 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.799 0.201
E34 Other endocrine disorders
0.000 0.800 0.200
E22 Hyperfunction of pituitary gland
0.000 0.801 0.199
C60.9 Penis, unspecified
0.193 0.807 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.807 0.192
E44.0 Moderate protein-energy malnutrition
0.000 0.807 0.192
E51 Thiamine deficiency
0.000 0.809 0.191
C60.1 Glans penis
0.189 0.810 0.000
M35.1 Other overlap syndromes
0.000 0.812 0.188
E58 Dietary calcium deficiency
0.000 0.812 0.188
E26.9 Hyperaldosteronism, unspecified
0.000 0.812 0.188
E26.8 Other hyperaldosteronism
0.000 0.812 0.188
E26.1 Secondary hyperaldosteronism
0.000 0.812 0.188
M35.8 Other specified systemic involvement of connective tissue
0.000 0.812 0.188
E20.8 Other hypoparathyroidism
0.000 0.813 0.187
E20.1 Pseudohypoparathyroidism
0.000 0.813 0.187
E20.0 Idiopathic hypoparathyroidism
0.000 0.813 0.187
E56 Other vitamin deficiencies
0.000 0.814 0.186
M35.2 Behcet's disease
0.000 0.816 0.184
E65-E68 Obesity and other hyperalimentation
0.000 0.816 0.184
E25.9 Adrenogenital disorder, unspecified
0.000 0.817 0.183
E25.8 Other adrenogenital disorders
0.000 0.817 0.183
L45 Papulosquamous disorders in diseases classified elsewhere
0.181 0.818 0.000
L44 Other papulosquamous disorders
0.181 0.819 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.819 0.181
E63 Other nutritional deficiencies
0.000 0.819 0.181
E50 Vitamin A deficiency
0.000 0.819 0.181
E60 Dietary zinc deficiency
0.000 0.819 0.181
E59 Dietary selenium deficiency
0.000 0.819 0.181
E52 Niacin deficiency [pellagra]
0.000 0.819 0.181
C60.8 Overlapping lesion of penis
0.178 0.822 0.000
C60.2 Body of penis
0.178 0.822 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.824 0.176
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.824 0.176
M35.5 Multifocal fibrosclerosis
0.000 0.824 0.176
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.824 0.176
E61 Deficiency of other nutrient elements
0.000 0.824 0.176
C62 Malignant neoplasm of testis
0.174 0.826 0.000
E29.8 Other testicular dysfunction
0.000 0.828 0.172
E29.0 Testicular hyperfunction
0.000 0.828 0.172
C60.0 Prepuce
0.169 0.831 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.832 0.168
L41.1 Pityriasis lichenoides chronica
0.166 0.834 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.834 0.165
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.834 0.165
E16.4 Abnormal secretion of gastrin
0.000 0.834 0.165
E16.3 Increased secretion of glucagon
0.000 0.834 0.165
E34.8 Other specified endocrine disorders
0.000 0.837 0.163
L42 Pityriasis rosea
0.161 0.839 0.000
C83.3 Large cell (diffuse)
0.000 0.839 0.161
E54 Ascorbic acid deficiency
0.000 0.839 0.161
C63.9 Male genital organ, unspecified
0.158 0.842 0.000
C63.8 Overlapping lesion of male genital organs
0.158 0.842 0.000
C63.7 Other specified male genital organs
0.158 0.842 0.000
C63.1 Spermatic cord
0.158 0.842 0.000
C63.0 Epididymis
0.158 0.842 0.000
H00.1 Chalazion
0.158 0.842 0.000
E26.0 Primary hyperaldosteronism
0.000 0.844 0.156
E20.9 Hypoparathyroidism, unspecified
0.000 0.845 0.154
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.847 0.153
E34.3 Short stature, not elsewhere classified
0.000 0.848 0.151
E16.1 Other hypoglycaemia
0.000 0.849 0.151
E13.9 Without complications
0.000 0.850 0.150
C63.2 Scrotum
0.149 0.850 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.850 0.150
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.851 0.149
E51.2 Wernicke's encephalopathy
0.000 0.853 0.147
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.853 0.147
E27 Other disorders of adrenal gland
0.000 0.854 0.146
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.855 0.145
C85.1 B-cell lymphoma, unspecified
0.000 0.855 0.145
L41.9 Parapsoriasis, unspecified
0.145 0.855 0.000
L41.8 Other parapsoriasis
0.145 0.855 0.000
L41.5 Retiform parapsoriasis
0.145 0.855 0.000
L41.4 Large plaque parapsoriasis
0.145 0.855 0.000
L41.3 Small plaque parapsoriasis
0.145 0.855 0.000
L41.2 Lymphomatoid papulosis
0.145 0.855 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.145 0.855 0.000
E34.5 Androgen resistance syndrome
0.000 0.856 0.143
E34.4 Constitutional tall stature
0.000 0.856 0.143
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.856 0.143
E34.1 Other hypersecretion of intestinal hormones
0.000 0.856 0.143
E22.8 Other hyperfunction of pituitary gland
0.000 0.857 0.142
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.858 0.142
E56.1 Deficiency of vitamin K
0.000 0.860 0.139
E61.2 Magnesium deficiency
0.000 0.863 0.137
E51.9 Thiamine deficiency, unspecified
0.000 0.863 0.137
E51.8 Other manifestations of thiamine deficiency
0.000 0.863 0.137
E51.1 Beriberi
0.000 0.863 0.137
C81 Hodgkin's disease
0.000 0.863 0.137
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.866 0.134
E56.9 Vitamin deficiency, unspecified
0.000 0.866 0.134
E56.8 Deficiency of other vitamins
0.000 0.866 0.134
E56.0 Deficiency of vitamin E
0.000 0.866 0.134
E67 Other hyperalimentation
0.000 0.868 0.132
E68 Sequelae of hyperalimentation
0.000 0.868 0.132
L44.9 Papulosquamous disorder, unspecified
0.130 0.870 0.000
L44.8 Other specified papulosquamous disorders
0.130 0.870 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.130 0.870 0.000
L44.3 Lichen ruber moniliformis
0.130 0.870 0.000
L44.2 Lichen striatus
0.130 0.870 0.000
L44.1 Lichen nitidus
0.130 0.870 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.870 0.130
E50.8 Other manifestations of vitamin A deficiency
0.000 0.870 0.130
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.870 0.130
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.870 0.130
E50.5 Vitamin A deficiency with night blindness
0.000 0.870 0.130
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.870 0.130
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.870 0.130
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.870 0.130
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.870 0.130
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.870 0.130
E63.9 Nutritional deficiency, unspecified
0.000 0.870 0.130
E63.8 Other specified nutritional deficiencies
0.000 0.870 0.130
E63.1 Imbalance of constituents of food intake
0.000 0.870 0.130
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.870 0.130
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.870 0.130
E64.8 Sequelae of other nutritional deficiencies
0.000 0.870 0.130
E64.3 Sequelae of rickets
0.000 0.870 0.130
E64.2 Sequelae of vitamin C deficiency
0.000 0.870 0.130
E64.1 Sequelae of vitamin A deficiency
0.000 0.870 0.130
E64.0 Sequelae of protein-energy malnutrition
0.000 0.870 0.130
L44.0 Pityriasis rubra pilaris
0.129 0.870 0.000
C81.9 Hodgkin's disease, unspecified
0.000 0.874 0.126
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.874 0.126
E61.9 Deficiency of nutrient element, unspecified
0.000 0.874 0.126
E61.8 Deficiency of other specified nutrient elements
0.000 0.874 0.126
E61.7 Deficiency of multiple nutrient elements
0.000 0.874 0.126
E61.6 Vanadium deficiency
0.000 0.874 0.126
E61.5 Molybdenum deficiency
0.000 0.874 0.126
E61.4 Chromium deficiency
0.000 0.874 0.126
E61.3 Manganese deficiency
0.000 0.874 0.126
E61.0 Copper deficiency
0.000 0.874 0.126
C62.0 Undescended testis
0.125 0.875 0.000
E53 Deficiency of other B group vitamins
0.000 0.876 0.124
E55 Vitamin D deficiency
0.000 0.876 0.124
E29.1 Testicular hypofunction
0.000 0.876 0.124
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.878 0.122
C62.1 Descended testis
0.121 0.879 0.000
E22.1 Hyperprolactinaemia
0.000 0.879 0.121
C83.7 Burkitt's tumour
0.000 0.881 0.119
C81.2 Mixed cellularity
0.000 0.888 0.112
C81.1 Nodular sclerosis
0.000 0.888 0.112
E23.0 Hypopituitarism
0.000 0.888 0.111
E27.1 Primary adrenocortical insufficiency
0.000 0.889 0.111
C83.1 Small cleaved cell (diffuse)
0.000 0.891 0.109
C81.0 Lymphocytic predominance
0.000 0.892 0.108
C85.0 Lymphosarcoma
0.000 0.892 0.107
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.895 0.105
C83.6 Undifferentiated (diffuse)
0.000 0.895 0.105
C83.4 Immunoblastic (diffuse)
0.000 0.895 0.105
C83.2 Mixed small and large cell (diffuse)
0.000 0.895 0.105
E61.1 Iron deficiency
0.000 0.895 0.105
E65 Localised adiposity
0.000 0.895 0.104
E27.5 Adrenomedullary hyperfunction
0.000 0.895 0.105
E27.0 Other adrenocortical overactivity
0.000 0.895 0.105
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.896 0.104
E21.0 Primary hyperparathyroidism
0.000 0.897 0.103
E27.9 Disorder of adrenal gland, unspecified
0.000 0.897 0.103
K60.2 Anal fissure, unspecified
0.000 0.898 0.102
C86 Other specified types of T/NK-cell lymphoma
0.000 0.898 0.102
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.898 0.102
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.900 0.100
C83.5 Lymphoblastic (diffuse)
0.000 0.901 0.099
C88 Malignant immunoproliferative diseases
0.000 0.901 0.099
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.902 0.098
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.902 0.098
C81.3 Lymphocytic depletion
0.000 0.902 0.098
C93 Monocytic leukaemia
0.000 0.902 0.098
E67.8 Other specified hyperalimentation
0.000 0.905 0.095
E67.3 Hypervitaminosis D
0.000 0.905 0.095
E67.2 Megavitamin-B6 syndrome
0.000 0.905 0.095
E67.1 Hypercarotenaemia
0.000 0.905 0.095
E67.0 Hypervitaminosis A
0.000 0.905 0.095
C95 Leukaemia of unspecified cell type
0.000 0.905 0.095
C94 Other leukaemias of specified cell type
0.000 0.905 0.095
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.907 0.093
K60 Fissure and fistula of anal and rectal regions
0.000 0.907 0.093
H00 Hordeolum and chalazion
0.093 0.907 0.000
C81.7 Other Hodgkin's disease
0.000 0.909 0.091
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.911 0.089
E53.1 Pyridoxine deficiency
0.000 0.911 0.089
E53.0 Riboflavin deficiency
0.000 0.911 0.089
C92 Myeloid leukaemia
0.000 0.911 0.089
E55.0 Rickets, active
0.000 0.911 0.089
C82.3 Follicular lymphoma grade IIIa
0.000 0.912 0.088
K60.3 Anal fistula
0.000 0.912 0.088
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.912 0.088
L43 Lichen planus
0.086 0.913 0.001
C92.1 Chronic myeloid leukaemia
0.000 0.914 0.086
K60.0 Acute anal fissure
0.000 0.915 0.085
E22.0 Acromegaly and pituitary gigantism
0.000 0.918 0.082
E53.9 Vitamin B deficiency, unspecified
0.000 0.918 0.082
C84.0 Mycosis fungoides
0.000 0.919 0.081
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.920 0.080
K60.5 Anorectal fistula
0.000 0.920 0.080
H00.0 Hordeolum and other deep inflammation of eyelid
0.080 0.920 0.000
E34.9 Endocrine disorder, unspecified
0.001 0.920 0.079
C82.2 Large cell, follicular
0.000 0.921 0.079
E27.2 Addisonian crisis
0.000 0.921 0.078
E14.9 Without complications
0.000 0.922 0.078
E34.0 Carcinoid syndrome
0.001 0.923 0.076
C62.9 Testis, unspecified
0.077 0.923 0.000
C84.5 Other and unspecified T-cell lymphomas
0.000 0.924 0.076
C82.6 Cutaneous follicle centre lymphoma
0.000 0.924 0.076
C82.5 Diffuse follicle centre lymphoma
0.000 0.924 0.076
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.926 0.073
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.927 0.073
C86.4 Blastic NK-cell lymphoma
0.000 0.927 0.073
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.927 0.073
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.927 0.073
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.927 0.073
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.927 0.073
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.927 0.073
C96.8 Histiocytic sarcoma
0.000 0.927 0.073
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.927 0.073
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.927 0.073
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.927 0.073
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.927 0.073
C96.3 True histiocytic lymphoma
0.000 0.927 0.073
C96.2 Malignant mast cell tumour
0.000 0.927 0.073
C96.1 Malignant histiocytosis
0.000 0.927 0.073
C96.0 Letterer-Siwe disease
0.000 0.927 0.073
C95.9 Leukaemia, unspecified
0.000 0.927 0.073
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.928 0.072
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.928 0.072
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.928 0.072
C84.3 Lymphoepithelioid lymphoma
0.000 0.928 0.072
C84.2 T-zone lymphoma
0.000 0.928 0.072
C84.1 Sezary's diease
0.000 0.928 0.072
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.929 0.071
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.929 0.071
C88.7 Other malignant immunoproliferative diseases
0.000 0.929 0.071
C88.3 Immunoproliferative small intestinal disease
0.000 0.929 0.071
C88.2 Gamma heavy chain disease
0.000 0.929 0.071
C88.1 Alpha heavy chain disease
0.000 0.929 0.071
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.929 0.071
K60.4 Rectal fistula
0.000 0.929 0.071
C93.9 Monocytic leukaemia, unspecified
0.000 0.930 0.070
C93.7 Other monocytic leukaemia
0.000 0.930 0.070
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.930 0.070
C93.2 Subacute monocytic leukaemia
0.000 0.930 0.070
C93.0 Acute monocytic leukaemia
0.000 0.930 0.070
C95.7 Other leukaemia of unspecified cell type
0.000 0.932 0.068
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.932 0.068
C94.7 Other specified leukaemias
0.000 0.932 0.068
C94.5 Acute myelofibrosis
0.000 0.932 0.068
C94.4 Acute panmyelosis
0.000 0.932 0.068
C94.3 Mast cell leukaemia
0.000 0.932 0.068
C94.2 Acute megakaryoblastic leukaemia
0.000 0.932 0.068
C94.1 Chronic erythraemia
0.000 0.932 0.068
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.932 0.068
C82.4 Follicular lymphoma grade IIIb
0.000 0.933 0.067
C93.1 Chronic monocytic leukaemia
0.000 0.933 0.066
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.933 0.066
C82.0 Small cleaved cell, follicular
0.000 0.934 0.066
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.934 0.066
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.936 0.064
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.936 0.064
C92.3 Myeloid sarcoma
0.000 0.936 0.064
C92.2 Subacute myeloid leukaemia
0.000 0.936 0.064
C92.5 Acute myelomonocytic leukaemia
0.000 0.937 0.063
L43.3 Subacute (active) lichen planus
0.062 0.938 0.001
L43.2 Lichenoid drug reaction
0.062 0.938 0.001
L43.1 Bullous lichen planus
0.062 0.938 0.001
L43.0 Hypertrophic lichen planus
0.062 0.938 0.001
E04 Other non-toxic goitre
0.000 0.939 0.061
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.939 0.061
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.942 0.058
C95.0 Acute leukaemia of unspecified cell type
0.000 0.942 0.057
E16.2 Hypoglycaemia, unspecified
0.000 0.943 0.057
C84.4 Peripheral T-cell lymphoma
0.000 0.943 0.057
C92.9 Myeloid leukaemia, unspecified
0.000 0.943 0.056
E27.8 Other specified disorders of adrenal gland
0.000 0.944 0.056
C91 Lymphoid leukaemia
0.000 0.946 0.054
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.947 0.053
M35.3 Polymyalgia rheumatica
0.000 0.948 0.052
L43.8 Other lichen planus
0.049 0.950 0.001
C92.4 Acute promyelocytic leukaemia
0.000 0.950 0.050
C83.0 Small cell (diffuse)
0.000 0.950 0.049
K90-K93 Other diseases of the digestive system
0.000 0.951 0.049
C92.7 Other myeloid leukaemia
0.000 0.952 0.048
E53.8 Deficiency of other specified B group vitamins
0.000 0.952 0.047
C91.9 Lymphoid leukaemia, unspecified
0.000 0.954 0.046
E04.8 Other specified non-toxic goitre
0.000 0.956 0.044
E83 Disorders of mineral metabolism
0.040 0.956 0.004
C90 Multiple myeloma and malignant plasma cell neoplasms
0.001 0.960 0.039
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.961 0.039
C91.7 Other lymphoid leukaemia
0.000 0.961 0.039
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.961 0.039
C91.3 Prolymphocytic leukaemia
0.000 0.961 0.039
C91.2 Subacute lymphocytic leukaemia
0.000 0.961 0.039
C91.5 Adult T-cell leukaemia
0.000 0.961 0.039
Z51.3 Blood transfusion without reported diagnosis
0.000 0.961 0.039
E04.0 Non-toxic diffuse goitre
0.000 0.962 0.037
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.964 0.036
K50.0 Crohn's disease of small intestine
0.035 0.965 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.030 0.967 0.003
E83.8 Other disorders of mineral metabolism
0.029 0.968 0.003
E83.2 Disorders of zinc metabolism
0.029 0.968 0.003
E83.0 Disorders of copper metabolism
0.029 0.968 0.003
E55.9 Vitamin D deficiency, unspecified
0.000 0.968 0.032
C91.4 Hairy-cell leukaemia
0.000 0.969 0.031
C90.1 Plasma cell leukaemia
0.001 0.969 0.031
K60.1 Chronic anal fissure
0.000 0.971 0.029
C91.0 Acute lymphoblastic leukaemia
0.000 0.971 0.028
C92.0 Acute myeloid leukaemia
0.000 0.972 0.028
C90.3 Solitary plasmacytoma
0.001 0.972 0.027
K50.8 Other Crohn's disease
0.027 0.973 0.000
K50 Crohn's disease [regional enteritis]
0.027 0.973 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.974 0.026
K93.1 Megacolon in Chagas' disease
0.000 0.974 0.026
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.974 0.026
N05.2 Diffuse membranous glomerulonephritis
0.000 0.975 0.025
N05.9 Unspecified
0.000 0.975 0.025
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.025 0.975 0.000
N05 Unspecified nephritic syndrome
0.000 0.976 0.024
G63.2 Diabetic polyneuropathy
0.024 0.976 0.000
K50.1 Crohn's disease of large intestine
0.022 0.978 0.000
N05.1 Focal and segmental glomerular lesions
0.000 0.979 0.021
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.980 0.020
E83.3 Disorders of phosphorus metabolism
0.016 0.981 0.003
S72.30 Fracture of shaft of femur (closed)
0.019 0.981 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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