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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2517455
log Bayes Factor = 138.347
Chromosome 6   position 31,059,900  (GRCh37) Explore rs2517455 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
L40 Psoriasis
0.999 0.001 0.000
E07 Other disorders of thyroid
0.000 0.001 0.999
E07.9 Disorder of thyroid, unspecified
0.000 0.002 0.998
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.007 0.993
L40.5 Arthropathic psoriasis
0.990 0.010 0.000
L40.0 Psoriasis vulgaris
0.985 0.015 0.000
E83.1 Disorders of iron metabolism
0.973 0.027 0.000
C61 Malignant neoplasm of prostate
0.899 0.101 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.151 0.849
L40.4 Guttate psoriasis
0.818 0.182 0.000
E03.8 Other specified hypothyroidism
0.000 0.197 0.803
K90 Intestinal malabsorption
0.000 0.209 0.791
L40.3 Pustulosis palmaris et plantaris
0.791 0.209 0.000
E06 Thyroiditis
0.000 0.239 0.761
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.241 0.758
L40.1 Generalised pustular psoriasis
0.738 0.262 0.000
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.716 0.284 0.000
E07.1 Dyshormogenetic goitre
0.000 0.284 0.716
E07.0 Hypersecretion of calcitonin
0.000 0.284 0.716
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.292 0.708
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.296 0.704
E07.8 Other specified disorders of thyroid
0.000 0.299 0.701
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.305 0.695
E05.8 Other thyrotoxicosis
0.000 0.338 0.662
K90.9 Intestinal malabsorption, unspecified
0.000 0.341 0.659
L40.8 Other psoriasis
0.648 0.352 0.000
E06.3 Autoimmune thyroiditis
0.000 0.365 0.635
E06.5 Other chronic thyroiditis
0.000 0.390 0.610
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.393 0.607
E03.1 Congenital hypothyroidism without goitre
0.000 0.397 0.602
K90.8 Other intestinal malabsorption
0.000 0.405 0.595
K90.3 Pancreatic steatorrhoea
0.000 0.433 0.567
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.433 0.567
K90.1 Tropical sprue
0.000 0.433 0.567
M35.0 Sicca syndrome [Sjogren]
0.000 0.441 0.559
E06.4 Drug-induced thyroiditis
0.000 0.454 0.546
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.454 0.546
E06.0 Acute thyroiditis
0.000 0.454 0.546
E10.9 Without complications
0.000 0.469 0.531
E06.1 Subacute thyroiditis
0.000 0.469 0.531
E10 Insulin-dependent diabetes mellitus
0.000 0.483 0.517
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.497 0.503
E10-E14 Diabetes mellitus
0.000 0.500 0.500
E10.3 With ophthalmic complications
0.000 0.508 0.492
E10.2 With renal complications
0.000 0.556 0.444
E20-E35 Disorders of other endocrine glands
0.000 0.620 0.380
E10.7 With multiple complications
0.000 0.627 0.373
E06.9 Thyroiditis, unspecified
0.000 0.631 0.368
E28 Ovarian dysfunction
0.000 0.634 0.366
E10.0 With coma
0.000 0.638 0.362
E12 Malnutrition-related diabetes mellitus
0.000 0.641 0.359
E10.4 With neurological complications
0.000 0.645 0.355
E14 Unspecified diabetes mellitus
0.000 0.650 0.350
E28.3 Primary ovarian failure
0.000 0.654 0.346
E40-E46 Malnutrition
0.000 0.655 0.345
E23 Hypofunction and other disorders of pituitary gland
0.000 0.671 0.329
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.671 0.329
E24 Cushing's syndrome
0.000 0.680 0.320
C60-C63 Malignant neoplasms of male genital organs
0.315 0.685 0.000
E10.8 With unspecified complications
0.000 0.686 0.314
E28.2 Polycystic ovarian syndrome
0.000 0.689 0.311
E13 Other specified diabetes mellitus
0.000 0.691 0.309
E14.3 With ophthalmic complications
0.000 0.692 0.308
E10.6 With other specified complications
0.000 0.693 0.306
E23.2 Diabetes insipidus
0.000 0.696 0.304
E24.2 Drug-induced Cushing's syndrome
0.000 0.715 0.285
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.721 0.279
E14.5 With peripheral circulatory complications
0.000 0.722 0.278
E31 Polyglandular dysfunction
0.000 0.725 0.275
E10.1 With ketoacidosis
0.000 0.727 0.273
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.727 0.272
E32 Diseases of thymus
0.000 0.727 0.272
E30 Disorders of puberty, not elsewhere classified
0.000 0.727 0.272
E10.5 With peripheral circulatory complications
0.000 0.737 0.262
E28.9 Ovarian dysfunction, unspecified
0.000 0.738 0.262
E28.8 Other ovarian dysfunction
0.000 0.738 0.262
E28.1 Androgen excess
0.000 0.738 0.262
E28.0 Oestrogen excess
0.000 0.738 0.262
E12.9 Without complications
0.000 0.743 0.257
E12.8 With unspecified complications
0.000 0.743 0.257
E12.7 With multiple complications
0.000 0.743 0.257
E12.6 With other specified complications
0.000 0.743 0.257
E12.5 With peripheral circulatory complications
0.000 0.743 0.257
E12.4 With neurological complications
0.000 0.743 0.257
E12.3 With ophthalmic complications
0.000 0.743 0.257
E12.2 With renal complications
0.000 0.743 0.257
E12.1 With ketoacidosis
0.000 0.743 0.257
E12.0 With coma
0.000 0.743 0.257
E14.8 With unspecified complications
0.000 0.743 0.257
E14.1 With ketoacidosis
0.000 0.743 0.257
E23.7 Disorder of pituitary gland, unspecified
0.000 0.744 0.256
E23.6 Other disorders of pituitary gland
0.000 0.744 0.256
L40-L45 Papulosquamous disorders
0.254 0.746 0.000
E14.7 With multiple complications
0.000 0.749 0.251
E14.0 With coma
0.000 0.749 0.251
E21.3 Hyperparathyroidism, unspecified
0.000 0.752 0.248
E14.6 With other specified complications
0.000 0.752 0.248
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.753 0.247
E45 Retarded development following protein-energy malnutrition
0.000 0.753 0.247
E43 Unspecified severe protein-energy malnutrition
0.000 0.753 0.247
E42 Marasmic kwashiorkor
0.000 0.753 0.247
E41 Nutritional marasmus
0.000 0.753 0.247
E40 Kwashiorkor
0.000 0.753 0.247
C60 Malignant neoplasm of penis
0.246 0.754 0.000
E26 Hyperaldosteronism
0.000 0.757 0.243
E20 Hypoparathyroidism
0.000 0.758 0.242
E13.3 With ophthalmic complications
0.000 0.759 0.241
E14.2 Withrenal complications
0.000 0.759 0.241
E25 Adrenogenital disorders
0.000 0.763 0.237
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.764 0.236
E23.1 Drug-induced hypopituitarism
0.000 0.764 0.236
E15 Nondiabetic hypoglycaemic coma
0.000 0.764 0.236
E24.0 Pituitary-dependent Cushing's disease
0.000 0.765 0.235
E14.4 With neurological complications
0.000 0.768 0.232
E46 Unspecified protein-energy malnutrition
0.000 0.768 0.232
M35 Other systemic involvement of connective tissue
0.000 0.770 0.230
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.770 0.230
E24.3 Ectopic ACTH syndrome
0.000 0.770 0.230
E24.1 Nelson's syndrome
0.000 0.770 0.230
E24.8 Other Cushing's syndrome
0.000 0.775 0.225
E50-E64 Other nutritional deficiencies
0.000 0.777 0.223
E29 Testicular dysfunction
0.000 0.778 0.222
E13.8 With unspecified complications
0.000 0.778 0.222
E13.7 With multiple complications
0.000 0.778 0.222
E13.6 With other specified complications
0.000 0.778 0.222
E13.5 With peripheral circulatory complications
0.000 0.778 0.222
E13.4 With neurological complications
0.000 0.778 0.222
E13.2 With renal complications
0.000 0.778 0.222
E13.1 With ketoacidosis
0.000 0.778 0.222
E13.0 With coma
0.000 0.778 0.222
C63 Malignant neoplasm of other and unspecified male genital organs
0.218 0.782 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.789 0.211
C83.3 Large cell (diffuse)
0.000 0.790 0.210
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.793 0.207
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.793 0.207
E16 Other disorders of pancreatic internal secretion
0.000 0.796 0.204
L41 Parapsoriasis
0.203 0.797 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.798 0.202
E21.2 Other hyperparathyroidism
0.000 0.798 0.202
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.799 0.201
E31.0 Autoimmune polyglandular failure
0.000 0.800 0.199
E31.9 Polyglandular dysfunction, unspecified
0.000 0.803 0.197
E31.8 Other polyglandular dysfunction
0.000 0.803 0.197
E31.1 Polyglandular hyperfunction
0.000 0.803 0.197
C85.1 B-cell lymphoma, unspecified
0.000 0.803 0.197
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.804 0.196
E30.9 Disorder of puberty, unspecified
0.000 0.804 0.195
E30.8 Other disorders of puberty
0.000 0.804 0.195
E30.1 Precocious puberty
0.000 0.804 0.195
E30.0 Delayed puberty
0.000 0.804 0.195
E32.9 Disease of thymus, unspecified
0.000 0.804 0.195
E32.8 Other diseases of thymus
0.000 0.804 0.195
E32.1 Abscess of thymus
0.000 0.804 0.195
E32.0 Persistent hyperplasia of thymus
0.000 0.804 0.195
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.804 0.195
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.804 0.195
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.804 0.195
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.807 0.193
C60.9 Penis, unspecified
0.192 0.808 0.000
M35.7 Hypermobility syndrome
0.000 0.809 0.191
C81 Hodgkin's disease
0.000 0.812 0.188
C60.1 Glans penis
0.188 0.812 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.813 0.187
E34 Other endocrine disorders
0.000 0.814 0.185
E22 Hyperfunction of pituitary gland
0.000 0.816 0.183
L45 Papulosquamous disorders in diseases classified elsewhere
0.182 0.818 0.000
L44 Other papulosquamous disorders
0.181 0.818 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.822 0.177
E44.0 Moderate protein-energy malnutrition
0.000 0.822 0.177
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.822 0.177
M35.1 Other overlap syndromes
0.000 0.823 0.177
C60.8 Overlapping lesion of penis
0.176 0.824 0.000
C60.2 Body of penis
0.176 0.824 0.000
C62 Malignant neoplasm of testis
0.176 0.824 0.000
M35.8 Other specified systemic involvement of connective tissue
0.000 0.824 0.176
C81.9 Hodgkin's disease, unspecified
0.000 0.824 0.176
E26.9 Hyperaldosteronism, unspecified
0.000 0.825 0.174
E26.8 Other hyperaldosteronism
0.000 0.825 0.174
E26.1 Secondary hyperaldosteronism
0.000 0.825 0.174
E20.8 Other hypoparathyroidism
0.000 0.826 0.174
E20.1 Pseudohypoparathyroidism
0.000 0.826 0.174
E20.0 Idiopathic hypoparathyroidism
0.000 0.826 0.174
M35.2 Behcet's disease
0.000 0.827 0.173
E25.9 Adrenogenital disorder, unspecified
0.000 0.830 0.170
E25.8 Other adrenogenital disorders
0.000 0.830 0.170
E51 Thiamine deficiency
0.000 0.831 0.169
K60.2 Anal fissure, unspecified
0.000 0.832 0.168
C60.0 Prepuce
0.168 0.832 0.000
E58 Dietary calcium deficiency
0.000 0.833 0.167
L41.1 Pityriasis lichenoides chronica
0.166 0.834 0.000
E56 Other vitamin deficiencies
0.000 0.834 0.165
E65-E68 Obesity and other hyperalimentation
0.000 0.835 0.165
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.835 0.165
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.835 0.165
M35.5 Multifocal fibrosclerosis
0.000 0.835 0.165
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.835 0.165
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.837 0.163
L42 Pityriasis rosea
0.162 0.838 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.840 0.160
E63 Other nutritional deficiencies
0.000 0.840 0.160
E50 Vitamin A deficiency
0.000 0.840 0.160
E60 Dietary zinc deficiency
0.000 0.840 0.160
E59 Dietary selenium deficiency
0.000 0.840 0.160
E52 Niacin deficiency [pellagra]
0.000 0.840 0.160
E29.8 Other testicular dysfunction
0.000 0.841 0.159
E29.0 Testicular hyperfunction
0.000 0.841 0.159
C83.7 Burkitt's tumour
0.000 0.841 0.159
C81.2 Mixed cellularity
0.000 0.841 0.159
K60 Fissure and fistula of anal and rectal regions
0.000 0.842 0.158
C63.9 Male genital organ, unspecified
0.156 0.843 0.000
C63.8 Overlapping lesion of male genital organs
0.156 0.843 0.000
C63.7 Other specified male genital organs
0.156 0.843 0.000
C63.1 Spermatic cord
0.156 0.843 0.000
C63.0 Epididymis
0.156 0.843 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.844 0.156
E61 Deficiency of other nutrient elements
0.000 0.845 0.155
H00.1 Chalazion
0.155 0.845 0.000
C81.1 Nodular sclerosis
0.000 0.847 0.153
E34.8 Other specified endocrine disorders
0.000 0.849 0.151
K60.3 Anal fistula
0.000 0.850 0.150
C63.2 Scrotum
0.148 0.852 0.000
C81.0 Lymphocytic predominance
0.000 0.852 0.148
K60.0 Acute anal fissure
0.000 0.852 0.148
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.854 0.146
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.854 0.146
E16.4 Abnormal secretion of gastrin
0.000 0.854 0.146
E16.3 Increased secretion of glucagon
0.000 0.854 0.146
L41.9 Parapsoriasis, unspecified
0.145 0.854 0.000
L41.8 Other parapsoriasis
0.145 0.854 0.000
L41.5 Retiform parapsoriasis
0.145 0.854 0.000
L41.4 Large plaque parapsoriasis
0.145 0.854 0.000
L41.3 Small plaque parapsoriasis
0.145 0.854 0.000
L41.2 Lymphomatoid papulosis
0.145 0.854 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.145 0.854 0.000
C85.0 Lymphosarcoma
0.000 0.855 0.145
E26.0 Primary hyperaldosteronism
0.000 0.855 0.145
E20.9 Hypoparathyroidism, unspecified
0.000 0.856 0.144
E54 Ascorbic acid deficiency
0.000 0.857 0.143
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.858 0.142
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.859 0.141
C83.6 Undifferentiated (diffuse)
0.000 0.859 0.141
C83.4 Immunoblastic (diffuse)
0.000 0.859 0.141
C83.2 Mixed small and large cell (diffuse)
0.000 0.859 0.141
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.859 0.141
E34.3 Short stature, not elsewhere classified
0.000 0.859 0.140
C83.1 Small cleaved cell (diffuse)
0.000 0.860 0.140
C86 Other specified types of T/NK-cell lymphoma
0.000 0.861 0.139
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.861 0.138
K60.5 Anorectal fistula
0.000 0.865 0.135
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.865 0.135
C81.3 Lymphocytic depletion
0.000 0.865 0.135
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.865 0.135
C88 Malignant immunoproliferative diseases
0.000 0.865 0.134
E13.9 Without complications
0.000 0.866 0.134
E27 Other disorders of adrenal gland
0.000 0.866 0.134
E34.5 Androgen resistance syndrome
0.000 0.866 0.133
E34.4 Constitutional tall stature
0.000 0.866 0.133
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.866 0.133
E34.1 Other hypersecretion of intestinal hormones
0.000 0.866 0.133
C93 Monocytic leukaemia
0.000 0.867 0.133
E16.1 Other hypoglycaemia
0.000 0.867 0.133
C83.5 Lymphoblastic (diffuse)
0.000 0.867 0.133
E22.8 Other hyperfunction of pituitary gland
0.000 0.868 0.132
C92 Myeloid leukaemia
0.000 0.868 0.131
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.869 0.131
E51.2 Wernicke's encephalopathy
0.000 0.869 0.131
L44.9 Papulosquamous disorder, unspecified
0.130 0.870 0.000
L44.8 Other specified papulosquamous disorders
0.130 0.870 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.130 0.870 0.000
L44.3 Lichen ruber moniliformis
0.130 0.870 0.000
L44.2 Lichen striatus
0.130 0.870 0.000
L44.1 Lichen nitidus
0.130 0.870 0.000
L44.0 Pityriasis rubra pilaris
0.130 0.870 0.000
C95 Leukaemia of unspecified cell type
0.000 0.871 0.129
C94 Other leukaemias of specified cell type
0.000 0.871 0.129
C92.1 Chronic myeloid leukaemia
0.000 0.873 0.127
C62.0 Undescended testis
0.126 0.873 0.000
C81.7 Other Hodgkin's disease
0.000 0.875 0.125
E56.1 Deficiency of vitamin K
0.000 0.876 0.124
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.876 0.124
C62.1 Descended testis
0.123 0.877 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.878 0.122
E51.8 Other manifestations of thiamine deficiency
0.000 0.878 0.122
E51.1 Beriberi
0.000 0.878 0.122
E61.2 Magnesium deficiency
0.000 0.878 0.121
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.880 0.120
K60.4 Rectal fistula
0.000 0.881 0.119
C82.3 Follicular lymphoma grade IIIa
0.000 0.881 0.119
E56.9 Vitamin deficiency, unspecified
0.000 0.881 0.119
E56.8 Deficiency of other vitamins
0.000 0.881 0.119
E56.0 Deficiency of vitamin E
0.000 0.881 0.119
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.881 0.119
E67 Other hyperalimentation
0.000 0.881 0.118
E68 Sequelae of hyperalimentation
0.000 0.881 0.118
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.881 0.118
E50.9 Vitamin A deficiency, unspecified
0.000 0.885 0.115
E50.8 Other manifestations of vitamin A deficiency
0.000 0.885 0.115
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.885 0.115
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.885 0.115
E50.5 Vitamin A deficiency with night blindness
0.000 0.885 0.115
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.885 0.115
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.885 0.115
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.885 0.115
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.885 0.115
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.885 0.115
E63.9 Nutritional deficiency, unspecified
0.000 0.885 0.115
E63.8 Other specified nutritional deficiencies
0.000 0.885 0.115
E63.1 Imbalance of constituents of food intake
0.000 0.885 0.115
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.885 0.115
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.885 0.115
E64.8 Sequelae of other nutritional deficiencies
0.000 0.885 0.115
E64.3 Sequelae of rickets
0.000 0.885 0.115
E64.2 Sequelae of vitamin C deficiency
0.000 0.885 0.115
E64.1 Sequelae of vitamin A deficiency
0.000 0.885 0.115
E64.0 Sequelae of protein-energy malnutrition
0.000 0.885 0.115
E29.1 Testicular hypofunction
0.000 0.886 0.114
E61.9 Deficiency of nutrient element, unspecified
0.000 0.888 0.112
E61.8 Deficiency of other specified nutrient elements
0.000 0.888 0.112
E61.7 Deficiency of multiple nutrient elements
0.000 0.888 0.112
E61.6 Vanadium deficiency
0.000 0.888 0.112
E61.5 Molybdenum deficiency
0.000 0.888 0.112
E61.4 Chromium deficiency
0.000 0.888 0.112
E61.3 Manganese deficiency
0.000 0.888 0.112
E61.0 Copper deficiency
0.000 0.888 0.112
E22.1 Hyperprolactinaemia
0.000 0.888 0.111
E23.0 Hypopituitarism
0.000 0.889 0.111
E55 Vitamin D deficiency
0.000 0.890 0.110
E53 Deficiency of other B group vitamins
0.000 0.891 0.109
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.891 0.109
C82.2 Large cell, follicular
0.000 0.893 0.107
C84.0 Mycosis fungoides
0.000 0.896 0.104
C82.6 Cutaneous follicle centre lymphoma
0.000 0.898 0.102
C82.5 Diffuse follicle centre lymphoma
0.000 0.898 0.102
E27.1 Primary adrenocortical insufficiency
0.000 0.898 0.102
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.900 0.100
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.900 0.100
C86.4 Blastic NK-cell lymphoma
0.000 0.900 0.100
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.900 0.100
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.900 0.100
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.900 0.100
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.900 0.100
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.900 0.099
C96.8 Histiocytic sarcoma
0.000 0.900 0.099
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.900 0.099
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.900 0.099
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.900 0.099
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.900 0.099
C96.3 True histiocytic lymphoma
0.000 0.900 0.099
C96.2 Malignant mast cell tumour
0.000 0.900 0.099
C96.1 Malignant histiocytosis
0.000 0.900 0.099
C96.0 Letterer-Siwe disease
0.000 0.900 0.099
C84.5 Other and unspecified T-cell lymphomas
0.000 0.900 0.099
C95.9 Leukaemia, unspecified
0.000 0.901 0.099
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.903 0.096
C88.7 Other malignant immunoproliferative diseases
0.000 0.903 0.096
C88.3 Immunoproliferative small intestinal disease
0.000 0.903 0.096
C88.2 Gamma heavy chain disease
0.000 0.903 0.096
C88.1 Alpha heavy chain disease
0.000 0.903 0.096
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.904 0.096
E27.5 Adrenomedullary hyperfunction
0.000 0.904 0.096
E27.0 Other adrenocortical overactivity
0.000 0.904 0.096
C93.9 Monocytic leukaemia, unspecified
0.000 0.904 0.096
C93.7 Other monocytic leukaemia
0.000 0.904 0.096
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.904 0.096
C93.2 Subacute monocytic leukaemia
0.000 0.904 0.096
C93.0 Acute monocytic leukaemia
0.000 0.904 0.096
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.905 0.095
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.905 0.094
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.905 0.094
C92.3 Myeloid sarcoma
0.000 0.905 0.094
C92.2 Subacute myeloid leukaemia
0.000 0.905 0.094
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.906 0.094
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.906 0.094
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.906 0.094
C84.3 Lymphoepithelioid lymphoma
0.000 0.906 0.094
C84.2 T-zone lymphoma
0.000 0.906 0.094
C84.1 Sezary's diease
0.000 0.906 0.094
E27.9 Disorder of adrenal gland, unspecified
0.000 0.906 0.094
E65 Localised adiposity
0.000 0.906 0.094
C95.7 Other leukaemia of unspecified cell type
0.000 0.907 0.093
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.907 0.093
C94.7 Other specified leukaemias
0.000 0.907 0.092
C94.5 Acute myelofibrosis
0.000 0.907 0.092
C94.4 Acute panmyelosis
0.000 0.907 0.092
C94.3 Mast cell leukaemia
0.000 0.907 0.092
C94.2 Acute megakaryoblastic leukaemia
0.000 0.907 0.092
C94.1 Chronic erythraemia
0.000 0.907 0.092
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.907 0.092
C92.5 Acute myelomonocytic leukaemia
0.000 0.908 0.092
E61.1 Iron deficiency
0.000 0.908 0.092
H00 Hordeolum and chalazion
0.092 0.908 0.000
C93.1 Chronic monocytic leukaemia
0.000 0.910 0.090
C82.4 Follicular lymphoma grade IIIb
0.000 0.910 0.090
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.910 0.090
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.910 0.090
C82.0 Small cleaved cell, follicular
0.000 0.911 0.089
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.913 0.087
L43 Lichen planus
0.087 0.913 0.000
E21.0 Primary hyperparathyroidism
0.000 0.914 0.086
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.915 0.085
E67.8 Other specified hyperalimentation
0.000 0.915 0.085
E67.3 Hypervitaminosis D
0.000 0.915 0.085
E67.2 Megavitamin-B6 syndrome
0.000 0.915 0.085
E67.1 Hypercarotenaemia
0.000 0.915 0.085
E67.0 Hypervitaminosis A
0.000 0.915 0.085
C92.9 Myeloid leukaemia, unspecified
0.000 0.917 0.083
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.917 0.083
C62.9 Testis, unspecified
0.083 0.917 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.079 0.921 0.000
E55.0 Rickets, active
0.000 0.921 0.079
E53.1 Pyridoxine deficiency
0.000 0.921 0.079
E53.0 Riboflavin deficiency
0.000 0.921 0.079
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.921 0.078
C95.0 Acute leukaemia of unspecified cell type
0.000 0.922 0.078
E22.0 Acromegaly and pituitary gigantism
0.000 0.924 0.076
C91 Lymphoid leukaemia
0.000 0.925 0.075
C84.4 Peripheral T-cell lymphoma
0.000 0.926 0.074
E34.9 Endocrine disorder, unspecified
0.001 0.926 0.073
C92.4 Acute promyelocytic leukaemia
0.000 0.927 0.073
E53.9 Vitamin B deficiency, unspecified
0.000 0.927 0.072
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.928 0.072
E27.2 Addisonian crisis
0.000 0.928 0.072
E34.0 Carcinoid syndrome
0.001 0.929 0.070
C92.7 Other myeloid leukaemia
0.000 0.929 0.071
C83.0 Small cell (diffuse)
0.000 0.934 0.066
E14.9 Without complications
0.000 0.935 0.065
C91.9 Lymphoid leukaemia, unspecified
0.000 0.937 0.063
L43.3 Subacute (active) lichen planus
0.062 0.937 0.001
L43.2 Lichenoid drug reaction
0.062 0.937 0.001
L43.1 Bullous lichen planus
0.062 0.937 0.001
L43.0 Hypertrophic lichen planus
0.062 0.937 0.001
E04 Other non-toxic goitre
0.000 0.938 0.062
C90 Multiple myeloma and malignant plasma cell neoplasms
0.001 0.946 0.053
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.946 0.054
C91.7 Other lymphoid leukaemia
0.000 0.946 0.054
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.946 0.054
C91.3 Prolymphocytic leukaemia
0.000 0.946 0.054
C91.2 Subacute lymphocytic leukaemia
0.000 0.946 0.054
C91.5 Adult T-cell leukaemia
0.000 0.946 0.054
K60.1 Chronic anal fissure
0.000 0.949 0.051
E27.8 Other specified disorders of adrenal gland
0.000 0.949 0.051
L43.8 Other lichen planus
0.050 0.950 0.001
C92.0 Acute myeloid leukaemia
0.000 0.951 0.049
K90-K93 Other diseases of the digestive system
0.000 0.951 0.049
E16.2 Hypoglycaemia, unspecified
0.000 0.953 0.047
E04.8 Other specified non-toxic goitre
0.000 0.955 0.045
N05.2 Diffuse membranous glomerulonephritis
0.000 0.956 0.044
E83 Disorders of mineral metabolism
0.040 0.956 0.004
C91.4 Hairy-cell leukaemia
0.000 0.957 0.043
N05.9 Unspecified
0.000 0.957 0.043
N05 Unspecified nephritic syndrome
0.000 0.957 0.043
C90.1 Plasma cell leukaemia
0.001 0.958 0.041
E53.8 Deficiency of other specified B group vitamins
0.000 0.959 0.041
M35.3 Polymyalgia rheumatica
0.000 0.959 0.041
Z51.3 Blood transfusion without reported diagnosis
0.000 0.960 0.040
C91.0 Acute lymphoblastic leukaemia
0.000 0.961 0.039
E04.0 Non-toxic diffuse goitre
0.000 0.962 0.038
C90.3 Solitary plasmacytoma
0.001 0.962 0.037
N05.1 Focal and segmental glomerular lesions
0.000 0.963 0.037
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.965 0.035
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.965 0.035
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.034 0.966 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.030 0.967 0.003
E83.8 Other disorders of mineral metabolism
0.029 0.968 0.003
E83.2 Disorders of zinc metabolism
0.029 0.968 0.003
E83.0 Disorders of copper metabolism
0.029 0.968 0.003
N05.6 Dense deposit disease
0.000 0.969 0.031
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.000 0.969 0.031
N05.0 Minor glomerular abnormality
0.000 0.969 0.031
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.000 0.970 0.030
N05.7 Diffuse crescentic glomerulonephritis
0.000 0.972 0.028
N05.8 Other
0.000 0.972 0.028
E55.9 Vitamin D deficiency, unspecified
0.000 0.972 0.028
K50.0 Crohn's disease of small intestine
0.026 0.974 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.975 0.025
K93.1 Megacolon in Chagas' disease
0.000 0.975 0.025
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.975 0.025

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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