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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2517502
log Bayes Factor = 71.8425
Chromosome 6   position 31,032,937  (GRCh37) Explore rs2517502 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
R31 Unspecified haematuria
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.002 0.998
E16.2 Hypoglycaemia, unspecified
0.000 0.003 0.997
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.003 0.997
E16 Other disorders of pancreatic internal secretion
0.000 0.003 0.997
E10.1 With ketoacidosis
0.000 0.003 0.997
E10.9 Without complications
0.000 0.005 0.995
E10.3 With ophthalmic complications
0.000 0.007 0.993
L40 Psoriasis
0.000 0.007 0.993
L40.5 Arthropathic psoriasis
0.000 0.017 0.983
D86.9 Sarcoidosis, unspecified
0.000 0.019 0.981
D86 Sarcoidosis
0.000 0.020 0.980
E00-E07 Disorders of thyroid gland
0.065 0.021 0.914
D80-D89 Certain disorders involving the immune mechanism
0.000 0.034 0.966
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.042 0.958
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.047 0.953
D70 Agranulocytosis
0.000 0.052 0.948
L40.0 Psoriasis vulgaris
0.000 0.052 0.948
E05 Thyrotoxicosis [hyperthyroidism]
0.011 0.076 0.913
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.081 0.919
E10.2 With renal complications
0.000 0.084 0.916
D50-D53 Nutritional anaemias
0.000 0.084 0.916
E11 Non-insulin-dependent diabetes mellitus
0.000 0.086 0.914
D86.1 Sarcoidosis of lymph nodes
0.000 0.096 0.904
D51 Vitamin B12 deficiency anaemia
0.000 0.103 0.897
E10.8 With unspecified complications
0.000 0.111 0.889
E10.4 With neurological complications
0.000 0.139 0.861
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.141 0.859
E11.5 With peripheral circulatory complications
0.000 0.143 0.857
E10.5 With peripheral circulatory complications
0.000 0.150 0.850
D72 Other disorders of white blood cells
0.000 0.157 0.843
D86.0 Sarcoidosis of lung
0.000 0.160 0.840
E10.6 With other specified complications
0.000 0.190 0.810
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.194 0.806
E50-E64 Other nutritional deficiencies
0.000 0.196 0.804
E11.3 With ophthalmic complications
0.000 0.203 0.797
D75 Other diseases of blood and blood-forming organs
0.000 0.206 0.794
E11.4 With neurological complications
0.000 0.208 0.792
D86.8 Sarcoidosis of other and combined sites
0.000 0.219 0.781
D53 Other nutritional anaemias
0.000 0.221 0.779
D80 Immunodeficiency with predominantly antibody defects
0.000 0.227 0.773
D55-D59 Haemolytic anaemias
0.000 0.228 0.772
E03 Other hypothyroidism
0.453 0.228 0.319
D72.8 Other specified disorders of white blood cells
0.000 0.235 0.765
L40.4 Guttate psoriasis
0.000 0.235 0.765
L40.1 Generalised pustular psoriasis
0.000 0.236 0.764
D83 Common variable immunodeficiency
0.000 0.240 0.760
E10.0 With coma
0.000 0.241 0.758
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.243 0.757
E11.8 With unspecified complications
0.000 0.245 0.755
E55 Vitamin D deficiency
0.000 0.248 0.752
D86.3 Sarcoidosis of skin
0.000 0.262 0.738
E14 Unspecified diabetes mellitus
0.000 0.263 0.737
E11.1 With ketoacidosis
0.000 0.276 0.724
D59 Acquired haemolytic anaemia
0.000 0.276 0.724
E40-E46 Malnutrition
0.000 0.278 0.722
E13 Other specified diabetes mellitus
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
E55.9 Vitamin D deficiency, unspecified
0.000 0.285 0.715
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.285 0.715
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.285 0.715
E16.4 Abnormal secretion of gastrin
0.000 0.285 0.715
E16.3 Increased secretion of glucagon
0.000 0.285 0.715
L40.3 Pustulosis palmaris et plantaris
0.000 0.288 0.712
L40.2 Acrodermatitis continua
0.000 0.288 0.712
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.298 0.702
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.047 0.298 0.655
E00 Congenital iodine-deficiency syndrome
0.047 0.298 0.655
D81 Combined immunodeficiencies
0.000 0.308 0.692
D74 Methaemoglobinaemia
0.000 0.317 0.683
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.317 0.683
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.317 0.683
D53.9 Nutritional anaemia, unspecified
0.000 0.319 0.681
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.324 0.676
E16.1 Other hypoglycaemia
0.000 0.324 0.676
E02 Subclinical iodine-deficiency hypothyroidism
0.046 0.325 0.629
E11.6 With other specified complications
0.000 0.337 0.663
E05.5 Thyroid crisis or storm
0.008 0.337 0.655
E05.4 Thyrotoxicosis factitia
0.008 0.337 0.655
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.008 0.337 0.655
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.008 0.337 0.655
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.338 0.662
D82 Immunodeficiency associated with other major defects
0.000 0.339 0.661
E06 Thyroiditis
0.035 0.342 0.623
E11.7 With multiple complications
0.000 0.345 0.655
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.348 0.652
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.357 0.643
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.357 0.643
D51.2 Transcobalamin II deficiency
0.000 0.357 0.643
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.357 0.643
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.357 0.642
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.361 0.639
D59.1 Other autoimmune haemolytic anaemias
0.000 0.375 0.624
D75.0 Familial erythrocytosis
0.000 0.380 0.620
E05.8 Other thyrotoxicosis
0.008 0.381 0.611
E14.3 With ophthalmic complications
0.000 0.381 0.619
D83.9 Common variable immunodeficiency, unspecified
0.000 0.387 0.613
E20-E35 Disorders of other endocrine glands
0.000 0.387 0.613
E27.1 Primary adrenocortical insufficiency
0.000 0.394 0.606
D72.9 Disorder of white blood cells, unspecified
0.000 0.395 0.605
D72.0 Genetic anomalies of leukocytes
0.000 0.395 0.605
E27 Other disorders of adrenal gland
0.000 0.396 0.604
D72.1 Eosinophilia
0.000 0.396 0.604
E51 Thiamine deficiency
0.000 0.396 0.603
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.397 0.603
E83.1 Disorders of iron metabolism
0.000 0.397 0.603
E14.8 With unspecified complications
0.000 0.400 0.600
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.403 0.597
D84 Other immunodeficiencies
0.000 0.419 0.581
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.423 0.577
E63 Other nutritional deficiencies
0.000 0.423 0.577
E50 Vitamin A deficiency
0.000 0.423 0.577
E60 Dietary zinc deficiency
0.000 0.423 0.577
E59 Dietary selenium deficiency
0.000 0.423 0.577
E52 Niacin deficiency [pellagra]
0.000 0.423 0.577
E70-E90 Metabolic disorders
0.000 0.425 0.575
E14.1 With ketoacidosis
0.000 0.432 0.568
E83 Disorders of mineral metabolism
0.000 0.435 0.565
D75.2 Essential thrombocytosis
0.000 0.437 0.563
E53 Deficiency of other B group vitamins
0.000 0.438 0.562
E14.6 With other specified complications
0.000 0.439 0.560
E06.9 Thyroiditis, unspecified
0.014 0.440 0.546
D53.8 Other specified nutritional anaemias
0.000 0.441 0.559
D53.2 Scorbutic anaemia
0.000 0.441 0.559
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.441 0.559
D53.0 Protein deficiency anaemia
0.000 0.441 0.559
E07 Other disorders of thyroid
0.083 0.445 0.472
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.445 0.554
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.445 0.554
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.445 0.554
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.445 0.554
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.445 0.554
D55 Anaemia due to enzyme disorders
0.000 0.446 0.554
E03.5 Myxoedema coma
0.325 0.447 0.229
E03.4 Atrophy of thyroid (acquired)
0.325 0.447 0.229
E03.3 Postinfectious hypothyroidism
0.325 0.447 0.229
E54 Ascorbic acid deficiency
0.000 0.447 0.553
E13.9 Without complications
0.000 0.448 0.552
D83.8 Other common variable immunodeficiencies
0.000 0.455 0.545
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.455 0.545
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.455 0.545
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.455 0.545
E03.0 Congenital hypothyroidism with diffuse goitre
0.323 0.455 0.222
E55.0 Rickets, active
0.000 0.461 0.539
E65-E68 Obesity and other hyperalimentation
0.000 0.463 0.537
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.464 0.536
D66 Hereditary factor VIII deficiency
0.000 0.467 0.533
E03.1 Congenital hypothyroidism without goitre
0.288 0.468 0.244
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.340 0.471 0.189
E58 Dietary calcium deficiency
0.000 0.471 0.529
E14.7 With multiple complications
0.000 0.472 0.528
E14.2 Withrenal complications
0.000 0.472 0.528
E14.0 With coma
0.000 0.472 0.528
D57 Sickle-cell disorders
0.000 0.473 0.527
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.473 0.527
E34 Other endocrine disorders
0.000 0.473 0.527
E56 Other vitamin deficiencies
0.000 0.476 0.524
E46 Unspecified protein-energy malnutrition
0.000 0.477 0.523
E88 Other metabolic disorders
0.000 0.478 0.522
L40.8 Other psoriasis
0.000 0.480 0.520
D59.8 Other acquired haemolytic anaemias
0.000 0.481 0.519
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.481 0.519
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.481 0.519
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.481 0.519
D59.3 Haemolytic-uraemic syndrome
0.000 0.481 0.519
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.481 0.519
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.481 0.519
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.481 0.519
E05.9 Thyrotoxicosis, unspecified
0.000 0.481 0.518
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.483 0.517
E45 Retarded development following protein-energy malnutrition
0.000 0.483 0.517
E43 Unspecified severe protein-energy malnutrition
0.000 0.483 0.517
E42 Marasmic kwashiorkor
0.000 0.483 0.517
E41 Nutritional marasmus
0.000 0.483 0.517
E40 Kwashiorkor
0.000 0.483 0.517
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.484 0.516
E13.8 With unspecified complications
0.000 0.484 0.516
E13.7 With multiple complications
0.000 0.484 0.516
E13.6 With other specified complications
0.000 0.484 0.516
E13.5 With peripheral circulatory complications
0.000 0.484 0.516
E13.4 With neurological complications
0.000 0.484 0.516
E13.2 With renal complications
0.000 0.484 0.516
E13.1 With ketoacidosis
0.000 0.484 0.516
E13.0 With coma
0.000 0.484 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E14.5 With peripheral circulatory complications
0.000 0.492 0.508
D75.1 Secondary polycythaemia
0.000 0.495 0.505
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.008 0.497 0.495
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.034 0.497 0.470
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.034 0.497 0.470
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.034 0.497 0.470
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.034 0.497 0.470
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.034 0.497 0.470
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.034 0.497 0.470
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.034 0.497 0.470
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.034 0.497 0.470
E85 Amyloidosis
0.000 0.499 0.501
D81.9 Combined immunodeficiency, unspecified
0.000 0.503 0.496
D81.8 Other combined immunodeficiencies
0.000 0.503 0.496
D81.7 Major histocompatibility complex class II deficiency
0.000 0.503 0.496
D81.6 Major histocompatibility complex class I deficiency
0.000 0.503 0.496
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.503 0.496
D81.4 Nezelof's syndrome
0.000 0.503 0.496
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.503 0.496
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.503 0.496
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.503 0.496
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.503 0.496
E03.8 Other specified hypothyroidism
0.296 0.506 0.198
D74.9 Methaemoglobinaemia, unspecified
0.000 0.510 0.490
D74.8 Other methaemoglobinaemias
0.000 0.510 0.490
D74.0 Congenital methaemoglobinaemia
0.000 0.510 0.490
E20 Hypoparathyroidism
0.000 0.510 0.490
E04 Other non-toxic goitre
0.004 0.512 0.484
D58 Other hereditary haemolytic anaemias
0.000 0.516 0.484
D69 Purpura and other haemorrhagic conditions
0.000 0.516 0.484
E14.4 With neurological complications
0.000 0.517 0.483
D67 Hereditary factor IX deficiency
0.000 0.517 0.483
E11.2 With renal complications
0.000 0.520 0.480
D50 Iron deficiency anaemia
0.000 0.521 0.479
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.526 0.474
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.526 0.474
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.526 0.474
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.526 0.474
D82.2 Immunodeficiency with short-limbed stature
0.000 0.526 0.474
D82.0 Wiskott-Aldrich syndrome
0.000 0.526 0.474
E13.3 With ophthalmic complications
0.000 0.526 0.474
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.526 0.474
E06.4 Drug-induced thyroiditis
0.025 0.528 0.447
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.025 0.528 0.447
E06.0 Acute thyroiditis
0.025 0.528 0.447
E34.9 Endocrine disorder, unspecified
0.000 0.529 0.471
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.531 0.468
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.538 0.462
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.539 0.461
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.539 0.461
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.539 0.461
E51.2 Wernicke's encephalopathy
0.000 0.540 0.460
D52 Folate deficiency anaemia
0.000 0.545 0.454
D84.1 Defects in the complement system
0.000 0.546 0.453
E25 Adrenogenital disorders
0.000 0.547 0.453
E85.4 Organ-limited amyloidosis
0.000 0.553 0.447
D82.1 Di George's syndrome
0.000 0.557 0.443
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.561 0.439
E32 Diseases of thymus
0.000 0.561 0.439
E31 Polyglandular dysfunction
0.000 0.561 0.439
E30 Disorders of puberty, not elsewhere classified
0.000 0.561 0.439
E27.5 Adrenomedullary hyperfunction
0.000 0.567 0.433
E27.0 Other adrenocortical overactivity
0.000 0.567 0.433
E51.9 Thiamine deficiency, unspecified
0.000 0.567 0.433
E51.8 Other manifestations of thiamine deficiency
0.000 0.567 0.433
E51.1 Beriberi
0.000 0.567 0.433
E79 Disorders of purine and pyrimidine metabolism
0.000 0.568 0.432
E34.0 Carcinoid syndrome
0.000 0.569 0.431
E27.2 Addisonian crisis
0.000 0.570 0.430
E53.9 Vitamin B deficiency, unspecified
0.000 0.571 0.429
E70 Disorders of aromatic amino-acid metabolism
0.000 0.573 0.427
D76.3 Other histiocytosis syndromes
0.000 0.580 0.420
E07.8 Other specified disorders of thyroid
0.042 0.581 0.377
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.581 0.418
D84.8 Other specified immunodeficiencies
0.000 0.583 0.416
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.583 0.416
E61 Deficiency of other nutrient elements
0.000 0.586 0.414
E50.9 Vitamin A deficiency, unspecified
0.000 0.586 0.413
E50.8 Other manifestations of vitamin A deficiency
0.000 0.586 0.413
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.586 0.413
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.586 0.413
E50.5 Vitamin A deficiency with night blindness
0.000 0.586 0.413
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.586 0.413
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.586 0.413
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.586 0.413
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.586 0.413
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.586 0.413
E63.9 Nutritional deficiency, unspecified
0.000 0.586 0.413
E63.8 Other specified nutritional deficiencies
0.000 0.586 0.413
E63.1 Imbalance of constituents of food intake
0.000 0.586 0.413
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.586 0.413
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.586 0.413
E64.8 Sequelae of other nutritional deficiencies
0.000 0.586 0.413
E64.3 Sequelae of rickets
0.000 0.586 0.413
E64.2 Sequelae of vitamin C deficiency
0.000 0.586 0.413
E64.1 Sequelae of vitamin A deficiency
0.000 0.586 0.413
E64.0 Sequelae of protein-energy malnutrition
0.000 0.586 0.413
E77 Disorders of glycoprotein metabolism
0.000 0.588 0.412
E76 Disorders of glycosaminoglycan metabolism
0.000 0.588 0.412
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.588 0.412
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.588 0.412
E27.8 Other specified disorders of adrenal gland
0.000 0.588 0.412
E06.1 Subacute thyroiditis
0.028 0.589 0.383
E88.9 Metabolic disorder, unspecified
0.000 0.592 0.407
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.593 0.407
E83.8 Other disorders of mineral metabolism
0.000 0.595 0.405
E83.2 Disorders of zinc metabolism
0.000 0.595 0.405
E83.0 Disorders of copper metabolism
0.000 0.595 0.405
E04.0 Non-toxic diffuse goitre
0.002 0.595 0.403
E53.1 Pyridoxine deficiency
0.000 0.597 0.403
E53.0 Riboflavin deficiency
0.000 0.597 0.403
D69.2 Other nonthrombocytopenic purpura
0.000 0.598 0.402
E20.9 Hypoparathyroidism, unspecified
0.000 0.598 0.402
E06.3 Autoimmune thyroiditis
0.015 0.599 0.386
E11.0 With coma
0.000 0.599 0.400
E07.1 Dyshormogenetic goitre
0.059 0.602 0.338
E07.0 Hypersecretion of calcitonin
0.059 0.602 0.338
E22 Hyperfunction of pituitary gland
0.000 0.602 0.398
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.603 0.397
D55.8 Other anaemias due to enzyme disorders
0.000 0.603 0.397
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.603 0.397
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.603 0.397
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.603 0.397
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.603 0.397
D69.6 Thrombocytopenia, unspecified
0.000 0.603 0.397
K90 Intestinal malabsorption
0.000 0.603 0.397
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.604 0.396
D69.5 Secondary thrombocytopenia
0.000 0.606 0.394
E06.5 Other chronic thyroiditis
0.029 0.608 0.363
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.612 0.388
E88.3 Tumour lysis syndrome
0.000 0.614 0.386
E67 Other hyperalimentation
0.000 0.615 0.385
E68 Sequelae of hyperalimentation
0.000 0.615 0.385
E84 Cystic fibrosis
0.000 0.615 0.385
D89.3 Immune reconstitution syndrome
0.000 0.615 0.385
E04.9 Non-toxic goitre, unspecified
0.000 0.620 0.380
E72 Other disorders of amino-acid metabolism
0.000 0.622 0.378
E85.3 Secondary systemic amyloidosis
0.000 0.622 0.378
D57.8 Other sickle-cell disorders
0.000 0.622 0.378
D57.3 Sickle-cell trait
0.000 0.622 0.378
D57.2 Double heterozygous sickling disorders
0.000 0.622 0.378
D57.0 Sickle-cell anaemia with crisis
0.000 0.622 0.378
E34.5 Androgen resistance syndrome
0.000 0.622 0.378
E34.4 Constitutional tall stature
0.000 0.622 0.378
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.622 0.378
E34.1 Other hypersecretion of intestinal hormones
0.000 0.622 0.378
E56.9 Vitamin deficiency, unspecified
0.000 0.624 0.375
E56.8 Deficiency of other vitamins
0.000 0.624 0.375
E56.0 Deficiency of vitamin E
0.000 0.624 0.375
E44.1 Mild protein-energy malnutrition
0.000 0.629 0.371
E44.0 Moderate protein-energy malnutrition
0.000 0.629 0.371
D56 Thalassaemia
0.001 0.629 0.370
D89.1 Cryoglobulinaemia
0.000 0.631 0.369
D50.9 Iron deficiency anaemia, unspecified
0.000 0.636 0.364
E29 Testicular dysfunction
0.000 0.637 0.363
E34.3 Short stature, not elsewhere classified
0.000 0.638 0.362
E85.8 Other amyloidosis
0.000 0.640 0.359
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.640 0.359
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.640 0.359
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.640 0.359
E24 Cushing's syndrome
0.000 0.641 0.359
D58.2 Other haemoglobinopathies
0.000 0.642 0.357
D69.9 Haemorrhagic condition, unspecified
0.000 0.647 0.353
E88.8 Other specified metabolic disorders
0.000 0.647 0.353
E53.8 Deficiency of other specified B group vitamins
0.000 0.647 0.353
E20.8 Other hypoparathyroidism
0.000 0.649 0.351
E20.1 Pseudohypoparathyroidism
0.000 0.649 0.351
E20.0 Idiopathic hypoparathyroidism
0.000 0.649 0.351
D57.1 Sickle-cell anaemia without crisis
0.000 0.649 0.351
E04.8 Other specified non-toxic goitre
0.003 0.650 0.347
E74 Other disorders of carbohydrate metabolism
0.000 0.651 0.349
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.653 0.347
D58.1 Hereditary elliptocytosis
0.000 0.653 0.347
D69.8 Other specified haemorrhagic conditions
0.000 0.653 0.347
D50.8 Other iron deficiency anaemias
0.000 0.654 0.346
D50.1 Sideropenic dysphagia
0.000 0.656 0.344
E86 Volume depletion
0.000 0.657 0.343
E85.9 Amyloidosis, unspecified
0.000 0.658 0.342
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.658 0.342
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.662 0.338
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.665 0.335
E73 Lactose intolerance
0.000 0.667 0.333
E66 Obesity
0.000 0.668 0.332
S64.4 Injury of digital nerve of other finger
0.331 0.669 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.669 0.330
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.670 0.330
D69.1 Qualitative platelet defects
0.000 0.673 0.327
D52.8 Other folate deficiency anaemias
0.000 0.674 0.326
D52.1 Drug-induced folate deficiency anaemia
0.000 0.674 0.326
D52.0 Dietary folate deficiency anaemia
0.000 0.674 0.326
E25.9 Adrenogenital disorder, unspecified
0.000 0.675 0.325
E25.8 Other adrenogenital disorders
0.000 0.675 0.325
E56.1 Deficiency of vitamin K
0.000 0.677 0.322
E70.3 Albinism
0.000 0.678 0.322
E88.2 Lipomatosis, not elsewhere classified
0.000 0.684 0.316
E22.1 Hyperprolactinaemia
0.000 0.684 0.316
E30.9 Disorder of puberty, unspecified
0.000 0.685 0.315
E30.8 Other disorders of puberty
0.000 0.685 0.315
E30.1 Precocious puberty
0.000 0.685 0.315
E30.0 Delayed puberty
0.000 0.685 0.315
E31.9 Polyglandular dysfunction, unspecified
0.000 0.685 0.315
E31.8 Other polyglandular dysfunction
0.000 0.685 0.315
E31.1 Polyglandular hyperfunction
0.000 0.685 0.315
E31.0 Autoimmune polyglandular failure
0.000 0.685 0.315
E32.9 Disease of thymus, unspecified
0.000 0.685 0.315
E32.8 Other diseases of thymus
0.000 0.685 0.315
E32.1 Abscess of thymus
0.000 0.685 0.315
E32.0 Persistent hyperplasia of thymus
0.000 0.685 0.315
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.685 0.315
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.685 0.315
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.685 0.315
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.685 0.315
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.685 0.314
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.690 0.310
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.690 0.310
E79.1 Lesch-Nyhan syndrome
0.000 0.690 0.310
E26 Hyperaldosteronism
0.000 0.691 0.308
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.693 0.306
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.693 0.306
E70.2 Disorders of tyrosine metabolism
0.000 0.693 0.306
E70.1 Other hyperphenylalaninaemias
0.000 0.693 0.306
E70.0 Classical phenylketonuria
0.000 0.693 0.306
K90.9 Intestinal malabsorption, unspecified
0.000 0.695 0.305
D58.0 Hereditary spherocytosis
0.000 0.696 0.303
D69.4 Other primary thrombocytopenia
0.000 0.697 0.303
E61.9 Deficiency of nutrient element, unspecified
0.000 0.703 0.297
E61.8 Deficiency of other specified nutrient elements
0.000 0.703 0.297
E61.7 Deficiency of multiple nutrient elements
0.000 0.703 0.297
E61.6 Vanadium deficiency
0.000 0.703 0.297
E61.5 Molybdenum deficiency
0.000 0.703 0.297
E61.4 Chromium deficiency
0.000 0.703 0.297
E61.3 Manganese deficiency
0.000 0.703 0.297
E61.0 Copper deficiency
0.000 0.703 0.297
E71.3 Disorders of fatty-acid metabolism
0.000 0.704 0.296
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.704 0.296
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.704 0.296
E71.0 Maple-syrup-urine disease
0.000 0.704 0.296
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.704 0.296
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.704 0.296
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.704 0.296
E76.2 Other mucopolysaccharidoses
0.000 0.704 0.296
E76.1 Mucopolysaccharidosis, type II
0.000 0.704 0.296
E76.0 Mucopolysaccharidosis, type I
0.000 0.704 0.296
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.704 0.296
E77.8 Other disorders of glycoprotein metabolism
0.000 0.704 0.296
E77.1 Defects in glycoprotein degradation
0.000 0.704 0.296
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.704 0.296
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.705 0.295
E27.9 Disorder of adrenal gland, unspecified
0.000 0.705 0.294
E34.8 Other specified endocrine disorders
0.000 0.706 0.294
E65 Localised adiposity
0.000 0.708 0.292
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.715 0.285
E22.8 Other hyperfunction of pituitary gland
0.000 0.715 0.285
K90.3 Pancreatic steatorrhoea
0.000 0.715 0.285
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.715 0.285
K90.1 Tropical sprue
0.000 0.715 0.285
E22.0 Acromegaly and pituitary gigantism
0.000 0.717 0.283
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.718 0.282
E66.0 Obesity due to excess calories
0.000 0.719 0.281
E24.0 Pituitary-dependent Cushing's disease
0.000 0.722 0.277
E67.8 Other specified hyperalimentation
0.000 0.723 0.276
E67.3 Hypervitaminosis D
0.000 0.723 0.276
E67.2 Megavitamin-B6 syndrome
0.000 0.723 0.276
E67.1 Hypercarotenaemia
0.000 0.723 0.276
E67.0 Hypervitaminosis A
0.000 0.723 0.276
E84.8 Cystic fibrosis with other manifestations
0.000 0.724 0.276
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.724 0.276
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.724 0.276
K90.8 Other intestinal malabsorption
0.000 0.727 0.273
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.729 0.271
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.729 0.271
E72.5 Disorders of glycine metabolism
0.000 0.729 0.271
E72.4 Disorders of ornithine metabolism
0.000 0.729 0.271
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.729 0.271
E72.2 Disorders of urea cycle metabolism
0.000 0.729 0.271
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.729 0.271
D56.9 Thalassaemia, unspecified
0.001 0.734 0.265
D56.8 Other thalassaemias
0.001 0.734 0.265
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.001 0.734 0.265
D56.2 Delta-beta thalassaemia
0.001 0.734 0.265
D56.0 Alpha thalassaemia
0.001 0.734 0.265
E29.9 Testicular dysfunction, unspecified
0.000 0.739 0.261
E29.8 Other testicular dysfunction
0.000 0.739 0.261
E29.0 Testicular hyperfunction
0.000 0.739 0.261
E61.2 Magnesium deficiency
0.000 0.740 0.259
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.743 0.257
E24.3 Ectopic ACTH syndrome
0.000 0.743 0.257
E24.1 Nelson's syndrome
0.000 0.743 0.257
D60-D64 Aplastic and other anaemias
0.000 0.746 0.254
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.749 0.251
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.750 0.250
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.750 0.250
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.750 0.250
E74.2 Disorders of galactose metabolism
0.000 0.750 0.250
E74.1 Disorders of fructose metabolism
0.000 0.750 0.250
E74.0 Glycogen storage disease
0.000 0.750 0.250
E84.9 Cystic fibrosis, unspecified
0.000 0.751 0.249
D73 Diseases of spleen
0.000 0.752 0.248
E24.8 Other Cushing's syndrome
0.000 0.753 0.247

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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