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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2517534
log Bayes Factor = 110.691
Chromosome 6   position 31,017,334  (GRCh37) Explore rs2517534 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.006 0.994
E10-E14 Diabetes mellitus
0.000 0.007 0.993
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.010 0.990
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.013 0.987
E07 Other disorders of thyroid
0.000 0.018 0.982
E07.9 Disorder of thyroid, unspecified
0.000 0.028 0.972
E83.1 Disorders of iron metabolism
0.954 0.046 0.000
E10.2 With renal complications
0.000 0.092 0.908
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.102 0.898
C85.1 B-cell lymphoma, unspecified
0.000 0.107 0.893
C83.3 Large cell (diffuse)
0.000 0.111 0.889
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.111 0.889
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.112 0.888
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.113 0.887
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.130 0.870
E14 Unspecified diabetes mellitus
0.000 0.130 0.870
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.132 0.868
E40-E46 Malnutrition
0.000 0.152 0.848
C81 Hodgkin's disease
0.000 0.166 0.834
E10.4 With neurological complications
0.000 0.169 0.831
K90 Intestinal malabsorption
0.000 0.175 0.825
E03.8 Other specified hypothyroidism
0.000 0.190 0.810
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.197 0.803
E10.0 With coma
0.000 0.214 0.786
C82.3 Follicular lymphoma grade IIIa
0.000 0.227 0.773
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.248 0.752
E14.3 With ophthalmic complications
0.000 0.251 0.749
E46 Unspecified protein-energy malnutrition
0.000 0.254 0.746
C83.7 Burkitt's tumour
0.000 0.257 0.743
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.264 0.735
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.271 0.729
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.272 0.728
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.273 0.727
E06 Thyroiditis
0.000 0.273 0.727
E10.8 With unspecified complications
0.000 0.280 0.720
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.288 0.712
C81.9 Hodgkin's disease, unspecified
0.000 0.291 0.709
K90.9 Intestinal malabsorption, unspecified
0.000 0.293 0.707
C81.2 Mixed cellularity
0.000 0.294 0.706
E07.1 Dyshormogenetic goitre
0.000 0.296 0.704
E07.0 Hypersecretion of calcitonin
0.000 0.296 0.704
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.298 0.702
E14.8 With unspecified complications
0.000 0.302 0.698
C82.2 Large cell, follicular
0.000 0.302 0.698
C81.1 Nodular sclerosis
0.000 0.308 0.692
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.309 0.691
E05.8 Other thyrotoxicosis
0.000 0.310 0.690
E10.7 With multiple complications
0.000 0.311 0.689
E14.6 With other specified complications
0.000 0.313 0.687
E13 Other specified diabetes mellitus
0.000 0.327 0.673
E10.6 With other specified complications
0.000 0.334 0.666
E14.9 Without complications
0.000 0.351 0.649
E14.5 With peripheral circulatory complications
0.000 0.353 0.647
K90.8 Other intestinal malabsorption
0.000 0.354 0.646
C61 Malignant neoplasm of prostate
0.645 0.355 0.000
C85.0 Lymphosarcoma
0.000 0.356 0.644
E07.8 Other specified disorders of thyroid
0.000 0.356 0.644
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.362 0.637
C83.6 Undifferentiated (diffuse)
0.000 0.364 0.636
C83.4 Immunoblastic (diffuse)
0.000 0.364 0.636
C83.2 Mixed small and large cell (diffuse)
0.000 0.364 0.636
C83.1 Small cleaved cell (diffuse)
0.000 0.368 0.632
C81.0 Lymphocytic predominance
0.000 0.369 0.631
C86 Other specified types of T/NK-cell lymphoma
0.000 0.372 0.628
C82.6 Cutaneous follicle centre lymphoma
0.000 0.376 0.624
C82.5 Diffuse follicle centre lymphoma
0.000 0.376 0.624
E14.7 With multiple complications
0.000 0.376 0.624
E14.0 With coma
0.000 0.376 0.624
E10.1 With ketoacidosis
0.000 0.378 0.622
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.379 0.621
C82.4 Follicular lymphoma grade IIIb
0.000 0.380 0.620
C82.0 Small cleaved cell, follicular
0.000 0.388 0.611
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.392 0.608
E45 Retarded development following protein-energy malnutrition
0.000 0.392 0.608
E43 Unspecified severe protein-energy malnutrition
0.000 0.392 0.608
E42 Marasmic kwashiorkor
0.000 0.392 0.608
E41 Nutritional marasmus
0.000 0.392 0.608
E40 Kwashiorkor
0.000 0.392 0.608
E14.2 Withrenal complications
0.000 0.393 0.607
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.401 0.599
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.402 0.598
C81.3 Lymphocytic depletion
0.000 0.402 0.598
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.405 0.595
E03.1 Congenital hypothyroidism without goitre
0.000 0.408 0.591
K90.3 Pancreatic steatorrhoea
0.000 0.408 0.591
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.408 0.591
K90.1 Tropical sprue
0.000 0.408 0.591
C93 Monocytic leukaemia
0.000 0.412 0.588
E14.1 With ketoacidosis
0.000 0.417 0.583
C83.5 Lymphoblastic (diffuse)
0.000 0.421 0.579
E10.5 With peripheral circulatory complications
0.000 0.422 0.578
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.425 0.575
C94 Other leukaemias of specified cell type
0.000 0.425 0.575
E06.3 Autoimmune thyroiditis
0.000 0.426 0.574
C81.7 Other Hodgkin's disease
0.000 0.426 0.574
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.427 0.573
E50-E64 Other nutritional deficiencies
0.000 0.439 0.561
C88 Malignant immunoproliferative diseases
0.000 0.443 0.556
E16 Other disorders of pancreatic internal secretion
0.000 0.459 0.541
C95 Leukaemia of unspecified cell type
0.000 0.464 0.536
E14.4 With neurological complications
0.000 0.471 0.528
E15 Nondiabetic hypoglycaemic coma
0.000 0.478 0.522
E06.5 Other chronic thyroiditis
0.000 0.479 0.521
E06.4 Drug-induced thyroiditis
0.000 0.479 0.521
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.479 0.521
E06.0 Acute thyroiditis
0.000 0.479 0.521
E13.3 With ophthalmic complications
0.000 0.480 0.519
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.489 0.511
E12.8 With unspecified complications
0.000 0.489 0.511
E12.7 With multiple complications
0.000 0.489 0.511
E12.6 With other specified complications
0.000 0.489 0.511
E12.5 With peripheral circulatory complications
0.000 0.489 0.511
E12.4 With neurological complications
0.000 0.489 0.511
E12.3 With ophthalmic complications
0.000 0.489 0.511
E12.2 With renal complications
0.000 0.489 0.511
E12.1 With ketoacidosis
0.000 0.489 0.511
E12.0 With coma
0.000 0.489 0.511
E06.1 Subacute thyroiditis
0.000 0.493 0.506
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.513 0.487
E13.8 With unspecified complications
0.000 0.517 0.482
E13.7 With multiple complications
0.000 0.517 0.482
E13.6 With other specified complications
0.000 0.517 0.482
E13.5 With peripheral circulatory complications
0.000 0.517 0.482
E13.4 With neurological complications
0.000 0.517 0.482
E13.2 With renal complications
0.000 0.517 0.482
E13.1 With ketoacidosis
0.000 0.517 0.482
E13.0 With coma
0.000 0.517 0.482
E06.9 Thyroiditis, unspecified
0.000 0.518 0.482
C84.5 Other and unspecified T-cell lymphomas
0.000 0.530 0.470
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.543 0.457
C96.8 Histiocytic sarcoma
0.000 0.543 0.457
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.543 0.457
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.543 0.457
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.543 0.457
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.543 0.457
C96.3 True histiocytic lymphoma
0.000 0.543 0.457
C96.2 Malignant mast cell tumour
0.000 0.543 0.457
C96.1 Malignant histiocytosis
0.000 0.543 0.457
C96.0 Letterer-Siwe disease
0.000 0.543 0.457
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.549 0.450
C86.4 Blastic NK-cell lymphoma
0.000 0.549 0.450
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.549 0.450
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.549 0.450
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.549 0.450
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.549 0.450
E61 Deficiency of other nutrient elements
0.000 0.551 0.449
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.559 0.441
E51 Thiamine deficiency
0.000 0.560 0.440
E20-E35 Disorders of other endocrine glands
0.000 0.561 0.439
C92 Myeloid leukaemia
0.000 0.563 0.437
E44.1 Mild protein-energy malnutrition
0.000 0.564 0.436
E44.0 Moderate protein-energy malnutrition
0.000 0.564 0.436
C84.0 Mycosis fungoides
0.000 0.568 0.432
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.571 0.429
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.573 0.427
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.573 0.427
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.573 0.427
C84.3 Lymphoepithelioid lymphoma
0.000 0.573 0.427
C84.2 T-zone lymphoma
0.000 0.573 0.427
C84.1 Sezary's diease
0.000 0.573 0.427
C93.9 Monocytic leukaemia, unspecified
0.000 0.578 0.422
C93.7 Other monocytic leukaemia
0.000 0.578 0.422
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.578 0.422
C93.2 Subacute monocytic leukaemia
0.000 0.578 0.422
C93.0 Acute monocytic leukaemia
0.000 0.578 0.422
C94.7 Other specified leukaemias
0.000 0.587 0.412
C94.5 Acute myelofibrosis
0.000 0.587 0.412
C94.3 Mast cell leukaemia
0.000 0.587 0.412
C94.2 Acute megakaryoblastic leukaemia
0.000 0.587 0.412
C94.1 Chronic erythraemia
0.000 0.587 0.412
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.587 0.412
E58 Dietary calcium deficiency
0.000 0.590 0.410
C94.4 Acute panmyelosis
0.000 0.591 0.409
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.596 0.403
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.597 0.402
E63 Other nutritional deficiencies
0.000 0.597 0.402
E50 Vitamin A deficiency
0.000 0.597 0.402
E60 Dietary zinc deficiency
0.000 0.597 0.402
E59 Dietary selenium deficiency
0.000 0.597 0.402
E52 Niacin deficiency [pellagra]
0.000 0.597 0.402
E56 Other vitamin deficiencies
0.000 0.600 0.400
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.601 0.399
C88.7 Other malignant immunoproliferative diseases
0.000 0.601 0.399
C88.3 Immunoproliferative small intestinal disease
0.000 0.601 0.399
C88.2 Gamma heavy chain disease
0.000 0.601 0.399
C88.1 Alpha heavy chain disease
0.000 0.601 0.399
C92.1 Chronic myeloid leukaemia
0.000 0.603 0.397
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.610 0.389
E24 Cushing's syndrome
0.000 0.611 0.389
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.612 0.388
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.612 0.388
E16.4 Abnormal secretion of gastrin
0.000 0.612 0.388
E16.3 Increased secretion of glucagon
0.000 0.612 0.388
E13.9 Without complications
0.000 0.612 0.388
E61.2 Magnesium deficiency
0.000 0.613 0.386
C95.9 Leukaemia, unspecified
0.000 0.614 0.386
C95.7 Other leukaemia of unspecified cell type
0.000 0.616 0.384
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.616 0.384
E16.1 Other hypoglycaemia
0.000 0.624 0.376
C93.1 Chronic monocytic leukaemia
0.000 0.627 0.372
E23 Hypofunction and other disorders of pituitary gland
0.000 0.629 0.371
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.630 0.369
E54 Ascorbic acid deficiency
0.000 0.640 0.360
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.646 0.354
E51.2 Wernicke's encephalopathy
0.000 0.646 0.354
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.653 0.347
E23.2 Diabetes insipidus
0.000 0.658 0.342
E28 Ovarian dysfunction
0.000 0.658 0.341
C84.4 Peripheral T-cell lymphoma
0.000 0.663 0.337
E24.2 Drug-induced Cushing's syndrome
0.000 0.664 0.336
C83.0 Small cell (diffuse)
0.000 0.667 0.333
E61.9 Deficiency of nutrient element, unspecified
0.000 0.678 0.322
E61.8 Deficiency of other specified nutrient elements
0.000 0.678 0.322
E61.7 Deficiency of multiple nutrient elements
0.000 0.678 0.322
E61.6 Vanadium deficiency
0.000 0.678 0.322
E61.5 Molybdenum deficiency
0.000 0.678 0.322
E61.4 Chromium deficiency
0.000 0.678 0.322
E61.3 Manganese deficiency
0.000 0.678 0.322
E61.0 Copper deficiency
0.000 0.678 0.322
C91 Lymphoid leukaemia
0.000 0.679 0.321
E25 Adrenogenital disorders
0.000 0.681 0.319
E51.9 Thiamine deficiency, unspecified
0.000 0.684 0.316
E51.8 Other manifestations of thiamine deficiency
0.000 0.684 0.316
E51.1 Beriberi
0.000 0.684 0.316
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.685 0.315
E32 Diseases of thymus
0.000 0.685 0.315
E30 Disorders of puberty, not elsewhere classified
0.000 0.685 0.315
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.687 0.313
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.687 0.313
C92.3 Myeloid sarcoma
0.000 0.687 0.313
C92.2 Subacute myeloid leukaemia
0.000 0.687 0.313
E31 Polyglandular dysfunction
0.000 0.692 0.308
E21.3 Hyperparathyroidism, unspecified
0.000 0.692 0.308
C92.5 Acute myelomonocytic leukaemia
0.000 0.693 0.307
E24.9 Cushing's syndrome, unspecified
0.000 0.695 0.305
E24.0 Pituitary-dependent Cushing's disease
0.000 0.695 0.304
C95.0 Acute leukaemia of unspecified cell type
0.001 0.697 0.302
E28.3 Primary ovarian failure
0.000 0.698 0.302
E65-E68 Obesity and other hyperalimentation
0.000 0.698 0.301
E55 Vitamin D deficiency
0.000 0.699 0.301
E23.7 Disorder of pituitary gland, unspecified
0.000 0.702 0.298
E50.9 Vitamin A deficiency, unspecified
0.000 0.711 0.289
E50.8 Other manifestations of vitamin A deficiency
0.000 0.711 0.289
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.711 0.289
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.711 0.289
E50.5 Vitamin A deficiency with night blindness
0.000 0.711 0.289
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.711 0.289
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.711 0.289
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.711 0.289
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.711 0.289
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.711 0.289
E63.9 Nutritional deficiency, unspecified
0.000 0.711 0.289
E63.8 Other specified nutritional deficiencies
0.000 0.711 0.289
E63.1 Imbalance of constituents of food intake
0.000 0.711 0.289
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.711 0.289
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.711 0.289
E64.8 Sequelae of other nutritional deficiencies
0.000 0.711 0.289
E64.3 Sequelae of rickets
0.000 0.711 0.289
E64.2 Sequelae of vitamin C deficiency
0.000 0.711 0.289
E64.1 Sequelae of vitamin A deficiency
0.000 0.711 0.289
E64.0 Sequelae of protein-energy malnutrition
0.000 0.711 0.289
C90 Multiple myeloma and malignant plasma cell neoplasms
0.001 0.711 0.287
E56.9 Vitamin deficiency, unspecified
0.000 0.713 0.287
E56.8 Deficiency of other vitamins
0.000 0.713 0.287
E56.0 Deficiency of vitamin E
0.000 0.713 0.287
E61.1 Iron deficiency
0.000 0.715 0.285
E56.1 Deficiency of vitamin K
0.000 0.716 0.284
C91.9 Lymphoid leukaemia, unspecified
0.000 0.718 0.282
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.721 0.279
E24.3 Ectopic ACTH syndrome
0.000 0.721 0.279
E24.1 Nelson's syndrome
0.000 0.721 0.279
E53 Deficiency of other B group vitamins
0.000 0.722 0.278
E26 Hyperaldosteronism
0.000 0.726 0.274
C92.9 Myeloid leukaemia, unspecified
0.000 0.730 0.270
E23.6 Other disorders of pituitary gland
0.000 0.732 0.268
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.732 0.268
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.734 0.266
E23.1 Drug-induced hypopituitarism
0.000 0.734 0.266
C92.4 Acute promyelocytic leukaemia
0.000 0.734 0.265
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.738 0.262
E24.8 Other Cushing's syndrome
0.000 0.738 0.262
C92.7 Other myeloid leukaemia
0.000 0.748 0.252
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.751 0.249
E21.2 Other hyperparathyroidism
0.000 0.751 0.248
E22 Hyperfunction of pituitary gland
0.000 0.753 0.247
E28.9 Ovarian dysfunction, unspecified
0.000 0.755 0.245
E28.8 Other ovarian dysfunction
0.000 0.755 0.245
E28.1 Androgen excess
0.000 0.755 0.245
E28.0 Oestrogen excess
0.000 0.755 0.245
E20 Hypoparathyroidism
0.000 0.763 0.236
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.766 0.233
E21.4 Other specified disorders of parathyroid gland
0.000 0.768 0.232
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.770 0.230
C91.7 Other lymphoid leukaemia
0.000 0.770 0.230
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.770 0.230
C91.3 Prolymphocytic leukaemia
0.000 0.770 0.230
C91.2 Subacute lymphocytic leukaemia
0.000 0.770 0.230
E25.9 Adrenogenital disorder, unspecified
0.000 0.771 0.229
E25.8 Other adrenogenital disorders
0.000 0.771 0.229
E30.9 Disorder of puberty, unspecified
0.000 0.774 0.226
E30.8 Other disorders of puberty
0.000 0.774 0.226
E30.1 Precocious puberty
0.000 0.774 0.226
E30.0 Delayed puberty
0.000 0.774 0.226
E32.9 Disease of thymus, unspecified
0.000 0.774 0.226
E32.8 Other diseases of thymus
0.000 0.774 0.226
E32.1 Abscess of thymus
0.000 0.774 0.226
E32.0 Persistent hyperplasia of thymus
0.000 0.774 0.226
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.774 0.226
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.774 0.226
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.774 0.226
C90.1 Plasma cell leukaemia
0.001 0.775 0.224
C91.5 Adult T-cell leukaemia
0.000 0.777 0.222
E31.9 Polyglandular dysfunction, unspecified
0.000 0.779 0.221
E31.8 Other polyglandular dysfunction
0.000 0.779 0.221
E31.1 Polyglandular hyperfunction
0.000 0.779 0.221
H00.1 Chalazion
0.217 0.783 0.000
E67 Other hyperalimentation
0.000 0.783 0.216
E68 Sequelae of hyperalimentation
0.000 0.783 0.216
E55.0 Rickets, active
0.000 0.784 0.216
E29 Testicular dysfunction
0.000 0.785 0.215
E31.0 Autoimmune polyglandular failure
0.000 0.786 0.214
C90.3 Solitary plasmacytoma
0.001 0.793 0.206
K60.2 Anal fissure, unspecified
0.000 0.794 0.206
E11 Non-insulin-dependent diabetes mellitus
0.000 0.798 0.202
E53.1 Pyridoxine deficiency
0.000 0.800 0.199
E53.0 Riboflavin deficiency
0.000 0.800 0.199
E27 Other disorders of adrenal gland
0.000 0.802 0.198
C60-C63 Malignant neoplasms of male genital organs
0.197 0.803 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.804 0.196
E26.8 Other hyperaldosteronism
0.000 0.804 0.196
E26.1 Secondary hyperaldosteronism
0.000 0.804 0.196
E11.0 With coma
0.000 0.805 0.195
E16.2 Hypoglycaemia, unspecified
0.000 0.811 0.189
L40.9 Psoriasis, unspecified
0.186 0.814 0.000
C91.4 Hairy-cell leukaemia
0.000 0.818 0.182
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.819 0.181
K60 Fissure and fistula of anal and rectal regions
0.000 0.820 0.180
E21.0 Primary hyperparathyroidism
0.000 0.822 0.178
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.823 0.177
E22.8 Other hyperfunction of pituitary gland
0.000 0.823 0.177
E34 Other endocrine disorders
0.001 0.824 0.175
E22.1 Hyperprolactinaemia
0.000 0.827 0.173
E28.2 Polycystic ovarian syndrome
0.000 0.828 0.172
E20.1 Pseudohypoparathyroidism
0.000 0.830 0.170
E20.0 Idiopathic hypoparathyroidism
0.000 0.830 0.170
L40 Psoriasis
0.169 0.831 0.000
E53.9 Vitamin B deficiency, unspecified
0.000 0.835 0.165
E11.1 With ketoacidosis
0.000 0.839 0.161
E27.9 Disorder of adrenal gland, unspecified
0.000 0.839 0.161
K60.5 Anorectal fistula
0.000 0.839 0.161
K60.3 Anal fistula
0.000 0.840 0.160
E11.6 With other specified complications
0.000 0.844 0.156
E20.8 Other hypoparathyroidism
0.000 0.844 0.155
E67.8 Other specified hyperalimentation
0.000 0.845 0.155
E67.3 Hypervitaminosis D
0.000 0.845 0.155
E67.2 Megavitamin-B6 syndrome
0.000 0.845 0.155
E67.1 Hypercarotenaemia
0.000 0.845 0.155
E67.0 Hypervitaminosis A
0.000 0.845 0.155
E26.0 Primary hyperaldosteronism
0.000 0.845 0.155
E29.8 Other testicular dysfunction
0.000 0.845 0.154
E29.0 Testicular hyperfunction
0.000 0.845 0.154
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.846 0.154
K60.0 Acute anal fissure
0.000 0.846 0.154
L40.5 Arthropathic psoriasis
0.152 0.848 0.000
E65 Localised adiposity
0.000 0.850 0.150
L40.0 Psoriasis vulgaris
0.149 0.851 0.000
K60.4 Rectal fistula
0.000 0.852 0.148
E29.9 Testicular dysfunction, unspecified
0.000 0.854 0.146
M35.0 Sicca syndrome [Sjogren]
0.000 0.854 0.146
E11.7 With multiple complications
0.000 0.855 0.145
E27.5 Adrenomedullary hyperfunction
0.000 0.858 0.142
E27.0 Other adrenocortical overactivity
0.000 0.858 0.142
C63 Malignant neoplasm of other and unspecified male genital organs
0.140 0.860 0.000
C60 Malignant neoplasm of penis
0.137 0.863 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.863 0.137
L40.3 Pustulosis palmaris et plantaris
0.136 0.864 0.000
E34.8 Other specified endocrine disorders
0.000 0.868 0.131
C91.0 Acute lymphoblastic leukaemia
0.001 0.870 0.130
E34.3 Short stature, not elsewhere classified
0.001 0.872 0.128
H00 Hordeolum and chalazion
0.127 0.873 0.000
E34.5 Androgen resistance syndrome
0.001 0.874 0.126
E34.4 Constitutional tall stature
0.001 0.874 0.126
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.874 0.126
E34.1 Other hypersecretion of intestinal hormones
0.001 0.874 0.126
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.874 0.126
E23.0 Hypopituitarism
0.000 0.875 0.125
L40.1 Generalised pustular psoriasis
0.124 0.876 0.000
C90.2 Plasmacytoma, extramedullary
0.002 0.877 0.122
L40.2 Acrodermatitis continua
0.121 0.879 0.000
L40.8 Other psoriasis
0.119 0.881 0.000
E20.9 Hypoparathyroidism, unspecified
0.001 0.883 0.117
L40.4 Guttate psoriasis
0.117 0.883 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.885 0.115
C62 Malignant neoplasm of testis
0.113 0.887 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.889 0.110
E11.9 Without complications
0.000 0.892 0.108
H00.0 Hordeolum and other deep inflammation of eyelid
0.108 0.892 0.000
E27.2 Addisonian crisis
0.000 0.892 0.107
E83 Disorders of mineral metabolism
0.094 0.892 0.014
E27.8 Other specified disorders of adrenal gland
0.000 0.892 0.107
E11.8 With unspecified complications
0.000 0.893 0.106
E27.1 Primary adrenocortical insufficiency
0.000 0.899 0.101
C63.9 Male genital organ, unspecified
0.100 0.899 0.000
C63.8 Overlapping lesion of male genital organs
0.100 0.899 0.000
C63.7 Other specified male genital organs
0.100 0.899 0.000
C63.1 Spermatic cord
0.100 0.899 0.000
C63.0 Epididymis
0.100 0.899 0.000
C60.1 Glans penis
0.100 0.900 0.000
C63.2 Scrotum
0.099 0.901 0.000
C60.8 Overlapping lesion of penis
0.098 0.901 0.000
C60.2 Body of penis
0.098 0.901 0.000
C60.9 Penis, unspecified
0.097 0.903 0.000
C92.0 Acute myeloid leukaemia
0.000 0.904 0.096
C60.0 Prepuce
0.094 0.905 0.000
E11.2 With renal complications
0.000 0.911 0.089
C62.0 Undescended testis
0.081 0.919 0.000
E34.0 Carcinoid syndrome
0.001 0.921 0.078
E83.9 Disorder of mineral metabolism, unspecified
0.069 0.921 0.010
E83.8 Other disorders of mineral metabolism
0.067 0.923 0.010
E83.2 Disorders of zinc metabolism
0.067 0.923 0.010
E83.0 Disorders of copper metabolism
0.067 0.923 0.010
C62.1 Descended testis
0.076 0.924 0.000
E29.1 Testicular hypofunction
0.000 0.925 0.075
K60.1 Chronic anal fissure
0.000 0.927 0.073
E83.3 Disorders of phosphorus metabolism
0.064 0.930 0.006
E70-E90 Metabolic disorders
0.029 0.933 0.038
E11.5 With peripheral circulatory complications
0.000 0.936 0.064
C62.9 Testis, unspecified
0.062 0.938 0.000
E34.9 Endocrine disorder, unspecified
0.001 0.939 0.060
C91.1 Chronic lymphocytic leukaemia
0.000 0.945 0.055
L40-L45 Papulosquamous disorders
0.053 0.947 0.000
K90-K93 Other diseases of the digestive system
0.000 0.948 0.052
E04 Other non-toxic goitre
0.000 0.949 0.050
E77 Disorders of glycoprotein metabolism
0.021 0.952 0.027
E76 Disorders of glycosaminoglycan metabolism
0.021 0.952 0.027
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.021 0.952 0.027
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.021 0.952 0.027
E72 Other disorders of amino-acid metabolism
0.020 0.952 0.028
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.020 0.952 0.028
E70 Disorders of aromatic amino-acid metabolism
0.021 0.952 0.026
N05.2 Diffuse membranous glomerulonephritis
0.000 0.953 0.047
E79 Disorders of purine and pyrimidine metabolism
0.022 0.953 0.025
E84 Cystic fibrosis
0.023 0.953 0.024
E73 Lactose intolerance
0.016 0.953 0.030
M35 Other systemic involvement of connective tissue
0.000 0.954 0.046
E74 Other disorders of carbohydrate metabolism
0.020 0.954 0.026
N05 Unspecified nephritic syndrome
0.000 0.954 0.046
N05.9 Unspecified
0.000 0.954 0.046
E11.3 With ophthalmic complications
0.000 0.955 0.045
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.006 0.956 0.038
L41 Parapsoriasis
0.043 0.956 0.000
E88 Other metabolic disorders
0.027 0.957 0.016
E89.0 Postprocedural hypothyroidism
0.000 0.960 0.040
L44 Other papulosquamous disorders
0.039 0.961 0.000
E85 Amyloidosis
0.033 0.961 0.006
L45 Papulosquamous disorders in diseases classified elsewhere
0.038 0.962 0.000
M35.2 Behcet's disease
0.000 0.962 0.038
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.963 0.037
M35.1 Other overlap syndromes
0.000 0.963 0.037
N05.1 Focal and segmental glomerular lesions
0.000 0.963 0.037
L42 Pityriasis rosea
0.037 0.963 0.000
L41.1 Pityriasis lichenoides chronica
0.036 0.963 0.000
E04.8 Other specified non-toxic goitre
0.000 0.964 0.036
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.000 0.965 0.035
E71.3 Disorders of fatty-acid metabolism
0.015 0.965 0.020
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.015 0.965 0.020
E71.1 Other disorders of branched-chain amino-acid metabolism
0.015 0.965 0.020
E71.0 Maple-syrup-urine disease
0.015 0.965 0.020
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.015 0.965 0.020
E76.8 Other disorders of glucosaminoglycan metabolism
0.015 0.965 0.020
E76.3 Mucopolysaccharidosis, unspecified
0.015 0.965 0.020
E76.2 Other mucopolysaccharidoses
0.015 0.965 0.020
E76.1 Mucopolysaccharidosis, type II
0.015 0.965 0.020
E76.0 Mucopolysaccharidosis, type I
0.015 0.965 0.020
E77.9 Disorder of glycoprotein metabolism, unspecified
0.015 0.965 0.020
E77.8 Other disorders of glycoprotein metabolism
0.015 0.965 0.020

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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