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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2517537
log Bayes Factor = 80.8371
Chromosome 6   position 31,014,010  (GRCh37) Explore rs2517537 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
C83.3 Large cell (diffuse)
0.000 0.006 0.994
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.006 0.994
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.006 0.994
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.007 0.993
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.008 0.992
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.014 0.986
E83.1 Disorders of iron metabolism
0.985 0.015 0.000
C85.1 B-cell lymphoma, unspecified
0.000 0.015 0.985
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.030 0.970
C61 Malignant neoplasm of prostate
0.967 0.033 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.079 0.921
C81 Hodgkin's disease
0.000 0.083 0.917
L40.0 Psoriasis vulgaris
0.000 0.090 0.910
E07 Other disorders of thyroid
0.000 0.093 0.907
E03.8 Other specified hypothyroidism
0.000 0.131 0.869
C82.3 Follicular lymphoma grade IIIa
0.000 0.147 0.853
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.148 0.852
C82.2 Large cell, follicular
0.000 0.149 0.851
E07.9 Disorder of thyroid, unspecified
0.000 0.153 0.847
C83.7 Burkitt's tumour
0.000 0.163 0.837
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.176 0.824
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.211 0.789
L40.1 Generalised pustular psoriasis
0.000 0.212 0.788
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.214 0.786
C81.9 Hodgkin's disease, unspecified
0.000 0.223 0.777
L40.8 Other psoriasis
0.000 0.234 0.766
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.235 0.765
C81.1 Nodular sclerosis
0.000 0.252 0.748
C81.2 Mixed cellularity
0.000 0.267 0.733
L40.4 Guttate psoriasis
0.000 0.272 0.728
C82.0 Small cleaved cell, follicular
0.000 0.276 0.724
L40.2 Acrodermatitis continua
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.287 0.713
C85.0 Lymphosarcoma
0.000 0.287 0.713
C83.6 Undifferentiated (diffuse)
0.000 0.288 0.712
C83.4 Immunoblastic (diffuse)
0.000 0.288 0.712
C83.2 Mixed small and large cell (diffuse)
0.000 0.288 0.712
C82.6 Cutaneous follicle centre lymphoma
0.000 0.289 0.711
C82.5 Diffuse follicle centre lymphoma
0.000 0.289 0.711
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.293 0.707
C86 Other specified types of T/NK-cell lymphoma
0.000 0.293 0.706
C81.0 Lymphocytic predominance
0.000 0.296 0.704
C83.1 Small cleaved cell (diffuse)
0.000 0.309 0.691
C82.4 Follicular lymphoma grade IIIb
0.000 0.310 0.689
K90 Intestinal malabsorption
0.000 0.314 0.686
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.322 0.678
E06 Thyroiditis
0.000 0.326 0.674
C94 Other leukaemias of specified cell type
0.000 0.334 0.666
C84.5 Other and unspecified T-cell lymphomas
0.000 0.334 0.666
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.343 0.657
C81.3 Lymphocytic depletion
0.000 0.343 0.657
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.345 0.655
C83.5 Lymphoblastic (diffuse)
0.000 0.347 0.653
E07.1 Dyshormogenetic goitre
0.000 0.349 0.651
E07.0 Hypersecretion of calcitonin
0.000 0.349 0.651
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.350 0.650
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.354 0.646
C81.7 Other Hodgkin's disease
0.000 0.355 0.645
E07.8 Other specified disorders of thyroid
0.000 0.371 0.629
C93 Monocytic leukaemia
0.000 0.385 0.614
C84.0 Mycosis fungoides
0.000 0.405 0.595
L40.3 Pustulosis palmaris et plantaris
0.000 0.407 0.593
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.410 0.590
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.412 0.588
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.412 0.588
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.417 0.583
E05.8 Other thyrotoxicosis
0.000 0.418 0.582
E03.1 Congenital hypothyroidism without goitre
0.000 0.427 0.572
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.434 0.566
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.434 0.566
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.434 0.566
C84.3 Lymphoepithelioid lymphoma
0.000 0.434 0.566
C84.2 T-zone lymphoma
0.000 0.434 0.566
C84.1 Sezary's diease
0.000 0.434 0.566
C88 Malignant immunoproliferative diseases
0.000 0.438 0.562
C95 Leukaemia of unspecified cell type
0.000 0.447 0.552
K90.9 Intestinal malabsorption, unspecified
0.000 0.453 0.547
E10-E14 Diabetes mellitus
0.000 0.453 0.547
E10 Insulin-dependent diabetes mellitus
0.000 0.458 0.542
E10.3 With ophthalmic complications
0.000 0.469 0.531
E10.9 Without complications
0.000 0.475 0.525
E40-E46 Malnutrition
0.000 0.484 0.515
E06.3 Autoimmune thyroiditis
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.489 0.511
C96.8 Histiocytic sarcoma
0.000 0.489 0.511
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.489 0.511
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.489 0.511
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.489 0.511
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.489 0.511
C96.3 True histiocytic lymphoma
0.000 0.489 0.511
C96.2 Malignant mast cell tumour
0.000 0.489 0.511
C96.1 Malignant histiocytosis
0.000 0.489 0.511
C96.0 Letterer-Siwe disease
0.000 0.489 0.511
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.493 0.507
C86.4 Blastic NK-cell lymphoma
0.000 0.493 0.507
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.493 0.507
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.493 0.507
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.493 0.507
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.493 0.507
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.499 0.500
K90.8 Other intestinal malabsorption
0.000 0.505 0.494
K90.3 Pancreatic steatorrhoea
0.000 0.508 0.492
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.508 0.492
K90.1 Tropical sprue
0.000 0.508 0.492
E06.5 Other chronic thyroiditis
0.000 0.517 0.483
E06.4 Drug-induced thyroiditis
0.000 0.517 0.483
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.517 0.483
E06.0 Acute thyroiditis
0.000 0.517 0.483
C94.7 Other specified leukaemias
0.000 0.522 0.478
C94.5 Acute myelofibrosis
0.000 0.522 0.478
C94.4 Acute panmyelosis
0.000 0.522 0.478
C94.3 Mast cell leukaemia
0.000 0.522 0.478
C94.2 Acute megakaryoblastic leukaemia
0.000 0.522 0.478
C94.1 Chronic erythraemia
0.000 0.522 0.478
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.522 0.478
E46 Unspecified protein-energy malnutrition
0.000 0.533 0.467
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.533 0.466
E20-E35 Disorders of other endocrine glands
0.000 0.545 0.455
C84.4 Peripheral T-cell lymphoma
0.000 0.549 0.450
E06.1 Subacute thyroiditis
0.000 0.556 0.444
E24 Cushing's syndrome
0.000 0.558 0.442
E06.9 Thyroiditis, unspecified
0.000 0.559 0.441
C93.9 Monocytic leukaemia, unspecified
0.000 0.559 0.440
C93.7 Other monocytic leukaemia
0.000 0.559 0.440
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.559 0.440
C93.2 Subacute monocytic leukaemia
0.000 0.559 0.440
C93.0 Acute monocytic leukaemia
0.000 0.559 0.440
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.568 0.431
E10.2 With renal complications
0.000 0.574 0.426
L40-L45 Papulosquamous disorders
0.000 0.578 0.422
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.581 0.419
E23 Hypofunction and other disorders of pituitary gland
0.000 0.585 0.415
E78.0 Pure hypercholesterolaemia
0.000 0.592 0.408
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.594 0.406
E24.9 Cushing's syndrome, unspecified
0.000 0.594 0.406
E10.8 With unspecified complications
0.000 0.595 0.405
E70-E90 Metabolic disorders
0.003 0.596 0.401
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.597 0.403
C88.7 Other malignant immunoproliferative diseases
0.000 0.597 0.403
C88.3 Immunoproliferative small intestinal disease
0.000 0.597 0.403
C88.2 Gamma heavy chain disease
0.000 0.597 0.403
C88.1 Alpha heavy chain disease
0.000 0.597 0.403
C95.7 Other leukaemia of unspecified cell type
0.000 0.603 0.396
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.603 0.396
E12 Malnutrition-related diabetes mellitus
0.000 0.607 0.392
E24.0 Pituitary-dependent Cushing's disease
0.000 0.611 0.389
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.615 0.385
C95.9 Leukaemia, unspecified
0.000 0.622 0.377
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.623 0.377
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.623 0.377
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.625 0.375
E10.0 With coma
0.000 0.628 0.372
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.630 0.370
E45 Retarded development following protein-energy malnutrition
0.000 0.630 0.370
E43 Unspecified severe protein-energy malnutrition
0.000 0.630 0.370
E42 Marasmic kwashiorkor
0.000 0.630 0.370
E41 Nutritional marasmus
0.000 0.630 0.370
E40 Kwashiorkor
0.000 0.630 0.370
E78.8 Other disorders of lipoprotein metabolism
0.000 0.630 0.369
E89.0 Postprocedural hypothyroidism
0.000 0.632 0.368
E10.7 With multiple complications
0.000 0.633 0.367
E13 Other specified diabetes mellitus
0.000 0.633 0.367
E24.2 Drug-induced Cushing's syndrome
0.000 0.635 0.365
C90 Multiple myeloma and malignant plasma cell neoplasms
0.003 0.635 0.362
E23.7 Disorder of pituitary gland, unspecified
0.000 0.639 0.361
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.360 0.640 0.000
E78.5 Hyperlipidaemia, unspecified
0.000 0.640 0.360
E10.6 With other specified complications
0.000 0.641 0.359
E23.2 Diabetes insipidus
0.000 0.643 0.357
C91 Lymphoid leukaemia
0.000 0.645 0.354
C60-C63 Malignant neoplasms of male genital organs
0.353 0.647 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.650 0.350
E14 Unspecified diabetes mellitus
0.000 0.651 0.349
C93.1 Chronic monocytic leukaemia
0.001 0.657 0.342
E23.6 Other disorders of pituitary gland
0.000 0.657 0.343
E25 Adrenogenital disorders
0.000 0.658 0.342
E28 Ovarian dysfunction
0.000 0.662 0.338
E10.4 With neurological complications
0.000 0.665 0.334
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.674 0.326
E32 Diseases of thymus
0.000 0.674 0.326
E30 Disorders of puberty, not elsewhere classified
0.000 0.674 0.326
C91.9 Lymphoid leukaemia, unspecified
0.000 0.677 0.323
L43 Lichen planus
0.000 0.677 0.323
E24.8 Other Cushing's syndrome
0.000 0.683 0.317
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.683 0.317
E24.3 Ectopic ACTH syndrome
0.000 0.683 0.317
E24.1 Nelson's syndrome
0.000 0.683 0.317
E31 Polyglandular dysfunction
0.000 0.683 0.317
E78.6 Lipoprotein deficiency
0.000 0.685 0.315
E89.4 Postprocedural ovarian failure
0.000 0.685 0.314
E89.2 Postprocedural hypoparathyroidism
0.000 0.688 0.312
L42 Pityriasis rosea
0.000 0.691 0.309
C95.0 Acute leukaemia of unspecified cell type
0.001 0.696 0.304
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.002 0.697 0.301
L44 Other papulosquamous disorders
0.000 0.697 0.302
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.697 0.302
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.702 0.298
E23.1 Drug-induced hypopituitarism
0.000 0.702 0.298
E10.5 With peripheral circulatory complications
0.000 0.703 0.297
E74 Other disorders of carbohydrate metabolism
0.002 0.705 0.293
C83.0 Small cell (diffuse)
0.001 0.709 0.290
E26 Hyperaldosteronism
0.000 0.710 0.290
E77 Disorders of glycoprotein metabolism
0.002 0.710 0.288
E76 Disorders of glycosaminoglycan metabolism
0.002 0.710 0.288
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.002 0.710 0.288
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.002 0.710 0.288
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.711 0.288
E72 Other disorders of amino-acid metabolism
0.002 0.713 0.285
E10.1 With ketoacidosis
0.000 0.713 0.287
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.714 0.286
E89.3 Postprocedural hypopituitarism
0.000 0.715 0.285
C90.1 Plasma cell leukaemia
0.002 0.715 0.283
E78.4 Other hyperlipidaemia
0.000 0.716 0.283
E12.9 Without complications
0.000 0.718 0.281
E12.8 With unspecified complications
0.000 0.718 0.281
E12.7 With multiple complications
0.000 0.718 0.281
E12.6 With other specified complications
0.000 0.718 0.281
E12.5 With peripheral circulatory complications
0.000 0.718 0.281
E12.4 With neurological complications
0.000 0.718 0.281
E12.3 With ophthalmic complications
0.000 0.718 0.281
E12.2 With renal complications
0.000 0.718 0.281
E12.1 With ketoacidosis
0.000 0.718 0.281
E12.0 With coma
0.000 0.718 0.281
C90.3 Solitary plasmacytoma
0.002 0.721 0.278
E14.3 With ophthalmic complications
0.000 0.721 0.279
C60 Malignant neoplasm of penis
0.277 0.723 0.000
E28.3 Primary ovarian failure
0.000 0.723 0.277
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.723 0.276
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.723 0.276
E89.5 Postprocedural testicular hypofunction
0.000 0.723 0.276
E73 Lactose intolerance
0.002 0.725 0.274
E78.2 Mixed hyperlipidaemia
0.000 0.728 0.272
E70 Disorders of aromatic amino-acid metabolism
0.002 0.729 0.269
E15 Nondiabetic hypoglycaemic coma
0.000 0.729 0.271
E78.1 Pure hyperglyceridaemia
0.000 0.730 0.270
L41 Parapsoriasis
0.000 0.731 0.269
E14.5 With peripheral circulatory complications
0.000 0.733 0.267
E44.1 Mild protein-energy malnutrition
0.000 0.735 0.265
E44.0 Moderate protein-energy malnutrition
0.000 0.735 0.265
E14.8 With unspecified complications
0.000 0.736 0.264
E21.2 Other hyperparathyroidism
0.000 0.736 0.264
E13.8 With unspecified complications
0.000 0.737 0.263
E13.7 With multiple complications
0.000 0.737 0.263
E13.6 With other specified complications
0.000 0.737 0.263
E13.5 With peripheral circulatory complications
0.000 0.737 0.263
E13.4 With neurological complications
0.000 0.737 0.263
E13.3 With ophthalmic complications
0.000 0.737 0.263
E13.2 With renal complications
0.000 0.737 0.263
E13.1 With ketoacidosis
0.000 0.737 0.263
E13.0 With coma
0.000 0.737 0.263
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.738 0.261
E78.3 Hyperchylomicronaemia
0.000 0.740 0.260
C63 Malignant neoplasm of other and unspecified male genital organs
0.259 0.741 0.000
L43.9 Lichen planus, unspecified
0.000 0.742 0.258
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.746 0.254
C91.7 Other lymphoid leukaemia
0.000 0.746 0.254
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.746 0.254
C91.3 Prolymphocytic leukaemia
0.000 0.746 0.254
C91.2 Subacute lymphocytic leukaemia
0.000 0.746 0.254
E14.6 With other specified complications
0.000 0.746 0.253
E14.7 With multiple complications
0.000 0.750 0.250
E14.0 With coma
0.000 0.750 0.250
E14.4 With neurological complications
0.000 0.750 0.250
E84 Cystic fibrosis
0.002 0.750 0.247
E79 Disorders of purine and pyrimidine metabolism
0.002 0.752 0.246
E25.9 Adrenogenital disorder, unspecified
0.000 0.754 0.245
E25.8 Other adrenogenital disorders
0.000 0.754 0.245
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.755 0.245
E89.1 Postprocedural hypoinsulinaemia
0.001 0.757 0.242
E28.9 Ovarian dysfunction, unspecified
0.000 0.757 0.242
E28.8 Other ovarian dysfunction
0.000 0.757 0.242
E28.1 Androgen excess
0.000 0.757 0.242
E28.0 Oestrogen excess
0.000 0.757 0.242
E13.9 Without complications
0.000 0.762 0.237
E21.4 Other specified disorders of parathyroid gland
0.000 0.763 0.237
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.763 0.236
C91.5 Adult T-cell leukaemia
0.001 0.765 0.234
E30.9 Disorder of puberty, unspecified
0.000 0.766 0.234
E30.8 Other disorders of puberty
0.000 0.766 0.234
E30.1 Precocious puberty
0.000 0.766 0.234
E30.0 Delayed puberty
0.000 0.766 0.234
E32.9 Disease of thymus, unspecified
0.000 0.766 0.234
E32.8 Other diseases of thymus
0.000 0.766 0.234
E32.1 Abscess of thymus
0.000 0.766 0.234
E32.0 Persistent hyperplasia of thymus
0.000 0.766 0.234
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.766 0.234
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.766 0.234
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.766 0.234
L43.3 Subacute (active) lichen planus
0.000 0.768 0.232
L43.2 Lichenoid drug reaction
0.000 0.768 0.232
L43.1 Bullous lichen planus
0.000 0.768 0.232
L43.0 Hypertrophic lichen planus
0.000 0.768 0.232
E75.5 Other lipid storage disorders
0.001 0.769 0.229
E20 Hypoparathyroidism
0.000 0.770 0.229
E16 Other disorders of pancreatic internal secretion
0.000 0.770 0.230
E31.9 Polyglandular dysfunction, unspecified
0.000 0.772 0.227
E31.8 Other polyglandular dysfunction
0.000 0.772 0.227
E31.1 Polyglandular hyperfunction
0.000 0.772 0.227
E14.1 With ketoacidosis
0.000 0.773 0.227
E50-E64 Other nutritional deficiencies
0.000 0.773 0.227
L43.8 Other lichen planus
0.000 0.776 0.224
E14.2 Withrenal complications
0.000 0.777 0.222
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.779 0.220
E22 Hyperfunction of pituitary gland
0.000 0.781 0.219
C88.0 Waldenstrom's macroglobulinaemia
0.001 0.782 0.217
E31.0 Autoimmune polyglandular failure
0.000 0.782 0.218
C92 Myeloid leukaemia
0.001 0.782 0.217
E75.6 Lipid storage disorder, unspecified
0.001 0.783 0.216
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.783 0.216
E75.3 Sphingolipidosis, unspecified
0.001 0.783 0.216
E75.2 Other sphingolipidosis
0.001 0.783 0.216
E75.1 Other gangliosidosis
0.001 0.783 0.216
E75.0 GM2 gangliosidosis
0.001 0.783 0.216
L44.9 Papulosquamous disorder, unspecified
0.000 0.783 0.217
L44.8 Other specified papulosquamous disorders
0.000 0.783 0.217
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.783 0.217
L44.3 Lichen ruber moniliformis
0.000 0.783 0.217
L44.2 Lichen striatus
0.000 0.783 0.217
L44.1 Lichen nitidus
0.000 0.783 0.217
L44.0 Pityriasis rubra pilaris
0.000 0.783 0.217
E23.0 Hypopituitarism
0.000 0.783 0.217
E88 Other metabolic disorders
0.002 0.787 0.211
C60.9 Penis, unspecified
0.212 0.788 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.789 0.210
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.789 0.210
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.789 0.210
E74.2 Disorders of galactose metabolism
0.001 0.789 0.210
E74.1 Disorders of fructose metabolism
0.001 0.789 0.210
C60.1 Glans penis
0.209 0.791 0.000
E83 Disorders of mineral metabolism
0.139 0.791 0.070
E26.9 Hyperaldosteronism, unspecified
0.000 0.792 0.208
E26.8 Other hyperaldosteronism
0.000 0.792 0.208
E26.1 Secondary hyperaldosteronism
0.000 0.792 0.208
E71.3 Disorders of fatty-acid metabolism
0.002 0.792 0.206
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.002 0.792 0.206
E71.1 Other disorders of branched-chain amino-acid metabolism
0.002 0.792 0.206
E71.0 Maple-syrup-urine disease
0.002 0.792 0.206
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.002 0.792 0.206
E76.8 Other disorders of glucosaminoglycan metabolism
0.002 0.792 0.206
E76.3 Mucopolysaccharidosis, unspecified
0.002 0.792 0.206
E76.2 Other mucopolysaccharidoses
0.002 0.792 0.206
E76.1 Mucopolysaccharidosis, type II
0.002 0.792 0.206
E76.0 Mucopolysaccharidosis, type I
0.002 0.792 0.206
E77.9 Disorder of glycoprotein metabolism, unspecified
0.002 0.792 0.206
E77.8 Other disorders of glycoprotein metabolism
0.002 0.792 0.206
E77.1 Defects in glycoprotein degradation
0.002 0.792 0.206
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.002 0.792 0.206
E28.2 Polycystic ovarian syndrome
0.000 0.793 0.207
E72.9 Disorder of amino-acid metabolism, unspecified
0.002 0.794 0.205
E72.8 Other specified disorders of amino-acid metabolism
0.002 0.794 0.205
E72.5 Disorders of glycine metabolism
0.002 0.794 0.205
E72.4 Disorders of ornithine metabolism
0.002 0.794 0.205
E72.3 Disorders of lysine and hydroxylysine metabolism
0.002 0.794 0.205
E72.2 Disorders of urea cycle metabolism
0.002 0.794 0.205
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.002 0.794 0.205
E74.0 Glycogen storage disease
0.001 0.794 0.204
E29 Testicular dysfunction
0.000 0.795 0.204
E72.0 Disorders of amino-acid transport
0.002 0.796 0.202
C60.0 Prepuce
0.202 0.797 0.000
C60.8 Overlapping lesion of penis
0.199 0.801 0.000
C60.2 Body of penis
0.199 0.801 0.000
E73.8 Other lactose intolerance
0.001 0.802 0.196
E73.1 Secondary lactase deficiency
0.001 0.802 0.196
E73.0 Congenital lactase deficiency
0.001 0.802 0.196
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.002 0.805 0.193
E70.8 Other disorders of aromatic amino-acid metabolism
0.002 0.805 0.193
E70.2 Disorders of tyrosine metabolism
0.002 0.805 0.193
E70.1 Other hyperphenylalaninaemias
0.002 0.805 0.193
E70.0 Classical phenylketonuria
0.002 0.805 0.193
L41.9 Parapsoriasis, unspecified
0.000 0.807 0.193
L41.8 Other parapsoriasis
0.000 0.807 0.193
L41.5 Retiform parapsoriasis
0.000 0.807 0.193
L41.4 Large plaque parapsoriasis
0.000 0.807 0.193
L41.3 Small plaque parapsoriasis
0.000 0.807 0.193
L41.2 Lymphomatoid papulosis
0.000 0.807 0.193
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.807 0.193
C63.2 Scrotum
0.192 0.808 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.810 0.190
C63.9 Male genital organ, unspecified
0.186 0.814 0.000
C63.8 Overlapping lesion of male genital organs
0.186 0.814 0.000
C63.7 Other specified male genital organs
0.186 0.814 0.000
C63.1 Spermatic cord
0.186 0.814 0.000
C63.0 Epididymis
0.186 0.814 0.000
E27 Other disorders of adrenal gland
0.000 0.817 0.183
E73.9 Lactose intolerance, unspecified
0.001 0.817 0.182
E88.8 Other specified metabolic disorders
0.001 0.819 0.180
E84.8 Cystic fibrosis with other manifestations
0.002 0.821 0.177
E84.1 Cystic fibrosis with intestinal manifestations
0.002 0.821 0.177
C62 Malignant neoplasm of testis
0.178 0.822 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.002 0.822 0.177
E79.8 Other disorders of purine and pyrimidine metabolism
0.002 0.822 0.177
E79.1 Lesch-Nyhan syndrome
0.002 0.822 0.177
E65-E68 Obesity and other hyperalimentation
0.000 0.824 0.176
E70.3 Albinism
0.002 0.824 0.174
E11 Non-insulin-dependent diabetes mellitus
0.000 0.825 0.175
E80.6 Other disorders of bilirubin metabolism
0.001 0.826 0.173
E51 Thiamine deficiency
0.000 0.826 0.173
E26.0 Primary hyperaldosteronism
0.000 0.828 0.172
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.830 0.169
E80.5 Crigler-Najjar syndrome
0.001 0.830 0.169
E80.3 Defects of catalase and peroxydase
0.001 0.830 0.169
E80.0 Hereditary erythropoietic porphyria
0.001 0.830 0.169
C91.4 Hairy-cell leukaemia
0.001 0.831 0.168
E80.2 Other porphyria
0.001 0.831 0.168
E88.2 Lipomatosis, not elsewhere classified
0.001 0.833 0.166
E84.9 Cystic fibrosis, unspecified
0.002 0.834 0.165
C92.1 Chronic myeloid leukaemia
0.000 0.834 0.166
E16.1 Other hypoglycaemia
0.000 0.835 0.165
E20.1 Pseudohypoparathyroidism
0.000 0.835 0.165
E20.0 Idiopathic hypoparathyroidism
0.000 0.835 0.165
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.835 0.165
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.835 0.165
E16.4 Abnormal secretion of gastrin
0.000 0.835 0.165
E16.3 Increased secretion of glucagon
0.000 0.835 0.165
E61 Deficiency of other nutrient elements
0.000 0.835 0.165
E14.9 Without complications
0.000 0.836 0.164
E56 Other vitamin deficiencies
0.000 0.836 0.163
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.837 0.163
E63 Other nutritional deficiencies
0.000 0.837 0.163
E50 Vitamin A deficiency
0.000 0.837 0.163
E60 Dietary zinc deficiency
0.000 0.837 0.163
E59 Dietary selenium deficiency
0.000 0.837 0.163
E52 Niacin deficiency [pellagra]
0.000 0.837 0.163
E11.0 With coma
0.000 0.839 0.161
L41.1 Pityriasis lichenoides chronica
0.000 0.840 0.160
E58 Dietary calcium deficiency
0.000 0.840 0.160
E11.1 With ketoacidosis
0.000 0.840 0.160
E27.9 Disorder of adrenal gland, unspecified
0.000 0.841 0.159
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.842 0.158
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.843 0.157
E22.8 Other hyperfunction of pituitary gland
0.000 0.843 0.157
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.001 0.844 0.156
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.001 0.844 0.156
C92.3 Myeloid sarcoma
0.001 0.844 0.156
C92.2 Subacute myeloid leukaemia
0.001 0.844 0.156
E84.0 Cystic fibrosis with pulmonary manifestations
0.002 0.844 0.154
C90.2 Plasmacytoma, extramedullary
0.003 0.846 0.152
E21.0 Primary hyperparathyroidism
0.000 0.848 0.152
E80.1 Porphyria cutanea tarda
0.001 0.850 0.149
E83.9 Disorder of mineral metabolism, unspecified
0.099 0.850 0.050
E83.8 Other disorders of mineral metabolism
0.099 0.850 0.050
E83.2 Disorders of zinc metabolism
0.099 0.850 0.050
E83.0 Disorders of copper metabolism
0.099 0.850 0.050
E29.8 Other testicular dysfunction
0.000 0.853 0.146
E29.0 Testicular hyperfunction
0.000 0.853 0.146
C92.5 Acute myelomonocytic leukaemia
0.001 0.854 0.145
E20.8 Other hypoparathyroidism
0.001 0.854 0.145
E88.3 Tumour lysis syndrome
0.002 0.854 0.144
E80.4 Gilbert's syndrome
0.000 0.857 0.143
E54 Ascorbic acid deficiency
0.000 0.862 0.138
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.002 0.863 0.135
E34 Other endocrine disorders
0.001 0.864 0.135
E51.2 Wernicke's encephalopathy
0.000 0.865 0.135
E88.9 Metabolic disorder, unspecified
0.002 0.866 0.132
E22.1 Hyperprolactinaemia
0.000 0.866 0.133
C91.0 Acute lymphoblastic leukaemia
0.001 0.867 0.132
E29.9 Testicular dysfunction, unspecified
0.001 0.867 0.132
E27.5 Adrenomedullary hyperfunction
0.000 0.868 0.131
E27.0 Other adrenocortical overactivity
0.000 0.868 0.131
E61.2 Magnesium deficiency
0.000 0.869 0.131
I83 Varicose veins of lower extremities
0.131 0.869 0.000
E11.6 With other specified complications
0.000 0.869 0.131
C92.9 Myeloid leukaemia, unspecified
0.001 0.870 0.129
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.871 0.129
C62.0 Undescended testis
0.128 0.872 0.000
C92.4 Acute promyelocytic leukaemia
0.001 0.872 0.127
E88.1 Lipodystrophy, not elsewhere classified
0.002 0.872 0.126
E83.3 Disorders of phosphorus metabolism
0.102 0.872 0.025
E67 Other hyperalimentation
0.000 0.873 0.126
E68 Sequelae of hyperalimentation
0.000 0.873 0.126
E11.7 With multiple complications
0.000 0.874 0.125
E51.9 Thiamine deficiency, unspecified
0.000 0.875 0.124
E51.8 Other manifestations of thiamine deficiency
0.000 0.875 0.124
E51.1 Beriberi
0.000 0.875 0.124
C62.1 Descended testis
0.123 0.877 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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