TreeWAS – Variant ID: rs2517592

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10.9 Without complications	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
E10.3 With ophthalmic complications	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.998	0.002	0.000
R31 Unspecified haematuria	0.000	0.002	0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.994	0.006	0.000
E14 Unspecified diabetes mellitus	0.994	0.006	0.000
E16 Other disorders of pancreatic internal secretion	0.991	0.009	0.000
E16.2 Hypoglycaemia, unspecified	0.986	0.014	0.000
E14.3 With ophthalmic complications	0.984	0.016	0.000
E10.4 With neurological complications	0.984	0.016	0.000
E20-E35 Disorders of other endocrine glands	0.981	0.019	0.000
E10.2 With renal complications	0.976	0.024	0.000
E27 Other disorders of adrenal gland	0.971	0.029	0.000
E27.1 Primary adrenocortical insufficiency	0.970	0.030	0.000
E03 Other hypothyroidism	0.964	0.036	0.000
E23 Hypofunction and other disorders of pituitary gland	0.946	0.054	0.000
E10.1 With ketoacidosis	0.943	0.057	0.000
K90 Intestinal malabsorption	0.922	0.078	0.000
E03.9 Hypothyroidism, unspecified	0.907	0.093	0.000
E23.2 Diabetes insipidus	0.891	0.109	0.000
E50-E64 Other nutritional deficiencies	0.891	0.109	0.000
E14.1 With ketoacidosis	0.855	0.144	0.000
E13 Other specified diabetes mellitus	0.841	0.159	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.820	0.180	0.000
E14.4 With neurological complications	0.809	0.191	0.000
E14.2 Withrenal complications	0.807	0.193	0.000
K90.9 Intestinal malabsorption, unspecified	0.806	0.194	0.000
E23.7 Disorder of pituitary gland, unspecified	0.802	0.198	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.797	0.203	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.796	0.204	0.000
K90.8 Other intestinal malabsorption	0.790	0.210	0.000
E10.7 With multiple complications	0.775	0.225	0.000
E83.1 Disorders of iron metabolism	0.000	0.234	0.766
E10.8 With unspecified complications	0.765	0.234	0.000
E24 Cushing's syndrome	0.765	0.235	0.000
E05.8 Other thyrotoxicosis	0.763	0.237	0.000
E53 Deficiency of other B group vitamins	0.759	0.241	0.000
E03.8 Other specified hypothyroidism	0.757	0.243	0.000
E14.5 With peripheral circulatory complications	0.755	0.245	0.000
E10.6 With other specified complications	0.743	0.257	0.000
E13.3 With ophthalmic complications	0.739	0.261	0.000
E27.2 Addisonian crisis	0.737	0.263	0.000
E11 Non-insulin-dependent diabetes mellitus	0.736	0.264	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.733	0.267	0.000
E23.6 Other disorders of pituitary gland	0.726	0.274	0.000
E31 Polyglandular dysfunction	0.718	0.282	0.000
E55 Vitamin D deficiency	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.713	0.287	0.000
E14.7 With multiple complications	0.713	0.287	0.000
E14.0 With coma	0.713	0.287	0.000
E16.1 Other hypoglycaemia	0.710	0.289	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.710	0.290	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.710	0.290	0.000
E16.4 Abnormal secretion of gastrin	0.710	0.290	0.000
E16.3 Increased secretion of glucagon	0.710	0.290	0.000
E14.6 With other specified complications	0.709	0.290	0.000
E10.5 With peripheral circulatory complications	0.706	0.294	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.703	0.296	0.000
E32 Diseases of thymus	0.703	0.296	0.000
E30 Disorders of puberty, not elsewhere classified	0.703	0.296	0.000
E27.5 Adrenomedullary hyperfunction	0.696	0.304	0.000
E27.0 Other adrenocortical overactivity	0.696	0.304	0.000
E14.8 With unspecified complications	0.695	0.305	0.000
E03.5 Myxoedema coma	0.691	0.309	0.000
E03.4 Atrophy of thyroid (acquired)	0.691	0.309	0.000
E03.3 Postinfectious hypothyroidism	0.691	0.309	0.000
E03.1 Congenital hypothyroidism without goitre	0.691	0.309	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.691	0.309	0.000
E40-E46 Malnutrition	0.689	0.311	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.685	0.315	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.679	0.321	0.000
E23.1 Drug-induced hypopituitarism	0.679	0.321	0.000
E53.8 Deficiency of other specified B group vitamins	0.676	0.324	0.000
E23.0 Hypopituitarism	0.673	0.327	0.000
E10.0 With coma	0.667	0.333	0.000
E25 Adrenogenital disorders	0.666	0.334	0.000
E51 Thiamine deficiency	0.666	0.334	0.000
K90.3 Pancreatic steatorrhoea	0.661	0.339	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.661	0.339	0.000
K90.1 Tropical sprue	0.661	0.339	0.000
E28 Ovarian dysfunction	0.654	0.346	0.000
E11.9 Without complications	0.653	0.347	0.000
E20 Hypoparathyroidism	0.651	0.349	0.000
E61 Deficiency of other nutrient elements	0.644	0.356	0.000
E58 Dietary calcium deficiency	0.641	0.359	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.640	0.360	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.639	0.361	0.000
E63 Other nutritional deficiencies	0.639	0.361	0.000
E56 Other vitamin deficiencies	0.639	0.361	0.000
E50 Vitamin A deficiency	0.639	0.361	0.000
E60 Dietary zinc deficiency	0.639	0.361	0.000
E59 Dietary selenium deficiency	0.639	0.361	0.000
E54 Ascorbic acid deficiency	0.639	0.361	0.000
E52 Niacin deficiency [pellagra]	0.639	0.361	0.000
E24.0 Pituitary-dependent Cushing's disease	0.626	0.373	0.000
E07 Other disorders of thyroid	0.619	0.381	0.000
E26 Hyperaldosteronism	0.616	0.384	0.000
E11.7 With multiple complications	0.612	0.388	0.000
E13.8 With unspecified complications	0.603	0.397	0.000
E13.7 With multiple complications	0.603	0.397	0.000
E13.6 With other specified complications	0.603	0.397	0.000
E13.5 With peripheral circulatory complications	0.603	0.397	0.000
E13.4 With neurological complications	0.603	0.397	0.000
E13.2 With renal complications	0.603	0.397	0.000
E13.1 With ketoacidosis	0.603	0.397	0.000
E13.0 With coma	0.603	0.397	0.000
E11.6 With other specified complications	0.602	0.398	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.401	0.599
E11.3 With ophthalmic complications	0.598	0.402	0.000
E24.2 Drug-induced Cushing's syndrome	0.597	0.403	0.000
K50.9 Crohn's disease, unspecified	0.000	0.403	0.597
E55.9 Vitamin D deficiency, unspecified	0.593	0.407	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.584	0.416	0.000
E13.9 Without complications	0.577	0.423	0.000
K50.8 Other Crohn's disease	0.000	0.431	0.569
E27.4 Other and unspecified adrenocortical insufficiency	0.567	0.432	0.000
K50.1 Crohn's disease of large intestine	0.000	0.435	0.565
K75.4 Autoimmune hepatitis	0.552	0.448	0.000
E24.8 Other Cushing's syndrome	0.549	0.451	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.549	0.451	0.000
E24.3 Ectopic ACTH syndrome	0.549	0.451	0.000
E24.1 Nelson's syndrome	0.549	0.451	0.000
K50-K52 Noninfective enteritis and colitis	0.029	0.452	0.519
K75 Other inflammatory liver diseases	0.548	0.452	0.000
E22 Hyperfunction of pituitary gland	0.545	0.455	0.000
K75.8 Other specified inflammatory liver diseases	0.544	0.456	0.000
E53.1 Pyridoxine deficiency	0.544	0.456	0.000
E53.0 Riboflavin deficiency	0.544	0.456	0.000
E06 Thyroiditis	0.533	0.466	0.000
E31.0 Autoimmune polyglandular failure	0.529	0.471	0.000
H36.0 Diabetic retinopathy	0.527	0.473	0.000
G56.0 Carpal tunnel syndrome	0.526	0.474	0.000
E31.9 Polyglandular dysfunction, unspecified	0.515	0.485	0.000
E31.8 Other polyglandular dysfunction	0.515	0.485	0.000
E31.1 Polyglandular hyperfunction	0.515	0.485	0.000
E53.9 Vitamin B deficiency, unspecified	0.514	0.486	0.000
E55.0 Rickets, active	0.514	0.486	0.000
K51 Ulcerative colitis	0.000	0.486	0.514
E12.9 Without complications	0.514	0.486	0.000
E12.8 With unspecified complications	0.514	0.486	0.000
E12.7 With multiple complications	0.514	0.486	0.000
E12.6 With other specified complications	0.514	0.486	0.000
E12.5 With peripheral circulatory complications	0.514	0.486	0.000
E12.4 With neurological complications	0.514	0.486	0.000
E12.3 With ophthalmic complications	0.514	0.486	0.000
E12.2 With renal complications	0.514	0.486	0.000
E12.1 With ketoacidosis	0.514	0.486	0.000
E12.0 With coma	0.514	0.486	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
E29 Testicular dysfunction	0.510	0.489	0.000
E11.5 With peripheral circulatory complications	0.506	0.494	0.000
E51.2 Wernicke's encephalopathy	0.505	0.495	0.000
E11.8 With unspecified complications	0.505	0.495	0.000
E30.9 Disorder of puberty, unspecified	0.504	0.495	0.000
E30.8 Other disorders of puberty	0.504	0.495	0.000
E30.1 Precocious puberty	0.504	0.495	0.000
E30.0 Delayed puberty	0.504	0.495	0.000
E32.9 Disease of thymus, unspecified	0.504	0.495	0.000
E32.8 Other diseases of thymus	0.504	0.495	0.000
E32.1 Abscess of thymus	0.504	0.495	0.000
E32.0 Persistent hyperplasia of thymus	0.504	0.495	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.504	0.495	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.504	0.495	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.504	0.495	0.000
K70-K77 Diseases of liver	0.501	0.499	0.000
E27.9 Disorder of adrenal gland, unspecified	0.495	0.505	0.000
E11.1 With ketoacidosis	0.495	0.505	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.494	0.506	0.000
E45 Retarded development following protein-energy malnutrition	0.494	0.506	0.000
E43 Unspecified severe protein-energy malnutrition	0.494	0.506	0.000
E42 Marasmic kwashiorkor	0.494	0.506	0.000
E41 Nutritional marasmus	0.494	0.506	0.000
E40 Kwashiorkor	0.494	0.506	0.000
E28.3 Primary ovarian failure	0.490	0.510	0.000
E21.4 Other specified disorders of parathyroid gland	0.490	0.510	0.000
E07.8 Other specified disorders of thyroid	0.485	0.515	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.516	0.484
K51.2 Ulcerative (chronic) proctitis	0.000	0.519	0.481
E61.1 Iron deficiency	0.480	0.520	0.000
E25.9 Adrenogenital disorder, unspecified	0.478	0.522	0.000
E25.8 Other adrenogenital disorders	0.478	0.522	0.000
E51.9 Thiamine deficiency, unspecified	0.477	0.522	0.000
E51.8 Other manifestations of thiamine deficiency	0.477	0.522	0.000
E51.1 Beriberi	0.477	0.522	0.000
K73 Chronic hepatitis, not elsewhere classified	0.474	0.526	0.000
K50.0 Crohn's disease of small intestine	0.000	0.529	0.471
E28.9 Ovarian dysfunction, unspecified	0.469	0.531	0.000
E28.8 Other ovarian dysfunction	0.469	0.531	0.000
E28.1 Androgen excess	0.469	0.531	0.000
E28.0 Oestrogen excess	0.469	0.531	0.000
E20.8 Other hypoparathyroidism	0.466	0.533	0.000
E20.1 Pseudohypoparathyroidism	0.466	0.533	0.000
E20.0 Idiopathic hypoparathyroidism	0.466	0.533	0.000
E46 Unspecified protein-energy malnutrition	0.466	0.534	0.000
E11.0 With coma	0.464	0.536	0.000
E61.9 Deficiency of nutrient element, unspecified	0.462	0.538	0.000
E61.8 Deficiency of other specified nutrient elements	0.462	0.538	0.000
E61.7 Deficiency of multiple nutrient elements	0.462	0.538	0.000
E61.6 Vanadium deficiency	0.462	0.538	0.000
E61.5 Molybdenum deficiency	0.462	0.538	0.000
E61.4 Chromium deficiency	0.462	0.538	0.000
E61.3 Manganese deficiency	0.462	0.538	0.000
E61.0 Copper deficiency	0.462	0.538	0.000
E21.2 Other hyperparathyroidism	0.459	0.541	0.000
E50.9 Vitamin A deficiency, unspecified	0.458	0.542	0.000
E50.8 Other manifestations of vitamin A deficiency	0.458	0.542	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.458	0.542	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.458	0.542	0.000
E50.5 Vitamin A deficiency with night blindness	0.458	0.542	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.458	0.542	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.458	0.542	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.458	0.542	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.458	0.542	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.458	0.542	0.000
E56.9 Vitamin deficiency, unspecified	0.458	0.542	0.000
E56.8 Deficiency of other vitamins	0.458	0.542	0.000
E56.1 Deficiency of vitamin K	0.458	0.542	0.000
E56.0 Deficiency of vitamin E	0.458	0.542	0.000
E63.9 Nutritional deficiency, unspecified	0.458	0.542	0.000
E63.8 Other specified nutritional deficiencies	0.458	0.542	0.000
E63.1 Imbalance of constituents of food intake	0.458	0.542	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.458	0.542	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.458	0.542	0.000
E64.8 Sequelae of other nutritional deficiencies	0.458	0.542	0.000
E64.3 Sequelae of rickets	0.458	0.542	0.000
E64.2 Sequelae of vitamin C deficiency	0.458	0.542	0.000
E64.1 Sequelae of vitamin A deficiency	0.458	0.542	0.000
E64.0 Sequelae of protein-energy malnutrition	0.458	0.542	0.000
E24.9 Cushing's syndrome, unspecified	0.454	0.546	0.000
E21.3 Hyperparathyroidism, unspecified	0.452	0.548	0.000
E21.0 Primary hyperparathyroidism	0.452	0.548	0.000
E61.2 Magnesium deficiency	0.448	0.552	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.448	0.552	0.000
E07.1 Dyshormogenetic goitre	0.444	0.556	0.000
E07.0 Hypersecretion of calcitonin	0.444	0.556	0.000
E26.9 Hyperaldosteronism, unspecified	0.442	0.558	0.000
E26.8 Other hyperaldosteronism	0.442	0.558	0.000
E26.1 Secondary hyperaldosteronism	0.442	0.558	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.441	0.559	0.000
H36 Retinal disorders in diseases classified elsewhere	0.439	0.561	0.000
K74 Fibrosis and cirrhosis of liver	0.436	0.564	0.000
E34 Other endocrine disorders	0.434	0.565	0.001
E21.5 Disorder of parathyroid gland, unspecified	0.431	0.569	0.000
E22.1 Hyperprolactinaemia	0.430	0.569	0.000
M35.0 Sicca syndrome [Sjogren]	0.425	0.575	0.000
G56 Mononeuropathies of upper limb	0.421	0.579	0.000
K51.8 Other ulcerative colitis	0.000	0.579	0.421
K51.5 Mucosal proctocolitis	0.000	0.582	0.418
E20.9 Hypoparathyroidism, unspecified	0.413	0.586	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.413	0.587	0.000
G51 Facial nerve disorders	0.411	0.589	0.000
E14.9 Without complications	0.411	0.589	0.000
G51.0 Bell's palsy	0.407	0.593	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.404	0.596	0.000
K90-K93 Other diseases of the digestive system	0.401	0.599	0.000
K75.9 Inflammatory liver disease, unspecified	0.399	0.601	0.000
K51.4 Pseudopolyposis of colon	0.000	0.602	0.398
K75.2 Nonspecific reactive hepatitis	0.393	0.607	0.000
K75.1 Phlebitis of portal vein	0.393	0.607	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.391	0.609	0.000
E22.8 Other hyperfunction of pituitary gland	0.391	0.609	0.000
E28.2 Polycystic ovarian syndrome	0.388	0.611	0.000
E06.9 Thyroiditis, unspecified	0.386	0.614	0.000
E06.5 Other chronic thyroiditis	0.382	0.617	0.000
E06.4 Drug-induced thyroiditis	0.382	0.617	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.382	0.617	0.000
E06.1 Subacute thyroiditis	0.382	0.617	0.000
E06.0 Acute thyroiditis	0.382	0.617	0.000
K74.3 Primary biliary cirrhosis	0.380	0.620	0.000
K72 Hepatic failure, not elsewhere classified	0.376	0.624	0.000
H30-H36 Disorders of choroid and retina	0.376	0.624	0.000
G58 Other mononeuropathies	0.376	0.624	0.000
K71 Toxic liver disease	0.375	0.625	0.000
K73.9 Chronic hepatitis, unspecified	0.372	0.628	0.000
Chapter XI Diseases of the digestive system	0.369	0.631	0.000
M35 Other systemic involvement of connective tissue	0.369	0.631	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.368	0.632	0.000
E29.9 Testicular dysfunction, unspecified	0.366	0.634	0.000
E29.8 Other testicular dysfunction	0.366	0.634	0.000
E29.0 Testicular hyperfunction	0.366	0.634	0.000
E11.2 With renal complications	0.366	0.634	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.638	0.362
K77 Liver disorders in diseases classified elsewhere	0.360	0.640	0.000
G58.9 Mononeuropathy, unspecified	0.358	0.642	0.000
Chapter I Certain infectious and parasitic diseases	0.357	0.643	0.000
# Top node	0.357	0.643	0.000
G51.3 Clonic hemifacial spasm	0.356	0.644	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.356	0.644	0.000
B35-B49 Mycoses	0.356	0.644	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.645	0.355
E26.0 Primary hyperaldosteronism	0.354	0.645	0.000
E44.1 Mild protein-energy malnutrition	0.354	0.646	0.000
E44.0 Moderate protein-energy malnutrition	0.354	0.646	0.000
H34 Retinal vascular occlusions	0.354	0.646	0.000
B02 Zoster [herpes zoster]	0.354	0.646	0.000
Chapter VI Diseases of the nervous system	0.353	0.647	0.000
B02.9 Zoster without complication	0.351	0.649	0.000
E27.8 Other specified disorders of adrenal gland	0.349	0.649	0.001
Chapter VII Diseases of the eye and adnexa	0.349	0.651	0.000
B37 Candidiasis	0.348	0.652	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.346	0.654	0.000
K74.5 Biliary cirrhosis, unspecified	0.344	0.656	0.000
B37.8 Candidiasis of other sites	0.344	0.656	0.000
M20-M25 Other joint disorders	0.342	0.658	0.000
H34.8 Other retinal vascular occlusions	0.340	0.660	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.340	0.660	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.340	0.660	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.340	0.660	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.334	0.666	0.000
B44 Aspergillosis	0.334	0.666	0.000
G52 Disorders of other cranial nerves	0.332	0.668	0.000
M05-M14 Inflammatory polyarthropathies	0.331	0.668	0.000
E65-E68 Obesity and other hyperalimentation	0.330	0.669	0.000
B37.0 Candidal stomatitis	0.330	0.670	0.000
G30-G32 Other degenerative diseases of the nervous system	0.329	0.671	0.000
M86-M90 Other osteopathies	0.328	0.672	0.000
B25-B34 Other viral diseases	0.327	0.673	0.000
G51.9 Disorder of facial nerve, unspecified	0.324	0.676	0.000
B00 Herpesviral [herpes simplex] infections	0.321	0.679	0.000
K70 Alcoholic liver disease	0.321	0.679	0.000
H43-H45 Disorders of vitreous body and globe	0.320	0.680	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.319	0.681	0.000
M11 Other crystal arthropathies	0.316	0.684	0.000
K74.0 Hepatic fibrosis	0.315	0.685	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.315	0.685	0.000
K74.4 Secondary biliary cirrhosis	0.312	0.687	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.312	0.687	0.000
K74.1 Hepatic sclerosis	0.312	0.687	0.000
G54 Nerve root and plexus disorders	0.312	0.688	0.000
E34.5 Androgen resistance syndrome	0.311	0.688	0.001
E34.4 Constitutional tall stature	0.311	0.688	0.001
E34.3 Short stature, not elsewhere classified	0.311	0.688	0.001
E34.2 Ectopic hormone secretion, not elsewhere classified	0.311	0.688	0.001
E34.1 Other hypersecretion of intestinal hormones	0.311	0.688	0.001
M60-M63 Disorders of muscles	0.311	0.689	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.311	0.689	0.000
M32 Systemic lupus erythematosus	0.309	0.691	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.309	0.691	0.000
G30 Alzheimer's disease	0.308	0.692	0.000
H43 Disorders of vitreous body	0.308	0.692	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.307	0.693	0.000
M86 Osteomyelitis	0.307	0.693	0.000
K72.0 Acute and subacute hepatic failure	0.306	0.694	0.000
M89 Other disorders of bone	0.304	0.696	0.000
M11.2 Other chondrocalcinosis	0.303	0.697	0.000
G56.1 Other lesions of median nerve	0.302	0.697	0.000
G56.4 Causalgia	0.302	0.698	0.000
B44.1 Other pulmonary aspergillosis	0.301	0.699	0.000
M10 Gout	0.301	0.699	0.000
H43.1 Vitreous haemorrhage	0.298	0.702	0.000
G30.9 Alzheimer's disease, unspecified	0.297	0.703	0.000
G51.4 Facial myokymia	0.295	0.705	0.000
G51.2 Melkersson's syndrome	0.295	0.705	0.000
G51.1 Geniculate ganglionitis	0.295	0.705	0.000
H18 Other disorders of cornea	0.295	0.705	0.000
M22 Disorders of patella	0.294	0.706	0.000
M33 Dermatopolymyositis	0.292	0.708	0.000
M13 Other arthritis	0.292	0.708	0.000
B25 Cytomegaloviral disease	0.291	0.709	0.000
K74.6 Other and unspecified cirrhosis of liver	0.291	0.709	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.291	0.709	0.000
M35.8 Other specified systemic involvement of connective tissue	0.289	0.711	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.288	0.712	0.000
B44.9 Aspergillosis, unspecified	0.287	0.713	0.000
M13.0 Polyarthritis, unspecified	0.287	0.713	0.000
E34.8 Other specified endocrine disorders	0.286	0.713	0.001
K71.1 Toxic liver disease with hepatic necrosis	0.285	0.715	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.285	0.715	0.000
G58.7 Mononeuritis multiplex	0.285	0.715	0.000
H31 Other disorders of choroid	0.285	0.715	0.000
B02.2 Zoster with other nervous system involvement	0.283	0.717	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.282	0.718	0.000
M86.9 Osteomyelitis, unspecified	0.281	0.719	0.000
M35.7 Hypermobility syndrome	0.280	0.720	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.279	0.721	0.000
G12 Spinal muscular atrophy and related syndromes	0.279	0.721	0.000
H30 Chorioretinal inflammation	0.279	0.721	0.000
H16 Keratitis	0.277	0.723	0.000
B00.5 Herpesviral ocular disease	0.277	0.723	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.277	0.723	0.000
G53.0 Postzoster neuralgia	0.277	0.723	0.000
M35.1 Other overlap syndromes	0.276	0.724	0.000
B00.9 Herpesviral infection, unspecified	0.275	0.725	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.275	0.725	0.000
G52.9 Cranial nerve disorder, unspecified	0.275	0.725	0.000
M62 Other disorders of muscle	0.274	0.726	0.000
H43.9 Disorder of vitreous body, unspecified	0.272	0.728	0.000
H34.9 Retinal vascular occlusion, unspecified	0.272	0.728	0.000
B00.8 Other forms of herpesviral infection	0.272	0.728	0.000
E22.0 Acromegaly and pituitary gigantism	0.271	0.729	0.000
M50-M54 Other dorsopathies	0.271	0.729	0.000
M89.9 Disorder of bone, unspecified	0.270	0.730	0.000
M10.9 Gout, unspecified	0.270	0.730	0.000
K70.0 Alcoholic fatty liver	0.270	0.730	0.000
K72.1 Chronic hepatic failure	0.270	0.730	0.000
M34 Systemic sclerosis	0.270	0.730	0.000
E34.0 Carcinoid syndrome	0.269	0.730	0.001
H32 Chorioretinal disorders in diseases classified elsewhere	0.270	0.730	0.000
G58.0 Intercostal neuropathy	0.269	0.730	0.000
K71.9 Toxic liver disease, unspecified	0.269	0.731	0.000
K71.8 Toxic liver disease with other disorders of liver	0.269	0.731	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.269	0.731	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.269	0.731	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.269	0.731	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.269	0.731	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.269	0.731	0.000
K71.2 Toxic liver disease with acute hepatitis	0.269	0.731	0.000
K71.0 Toxic liver disease with cholestasis	0.269	0.731	0.000
B02.3 Zoster ocular disease	0.269	0.731	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.268	0.731	0.000
G56.3 Lesion of radial nerve	0.268	0.732	0.000
A80-A89 Viral infections of the central nervous system	0.267	0.733	0.000
M35.2 Behcet's disease	0.267	0.733	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.267	0.733	0.000
H18.5 Hereditary corneal dystrophies	0.265	0.735	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.264	0.735	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.264	0.735	0.000
M35.5 Multifocal fibrosclerosis	0.264	0.735	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.264	0.735	0.000
B49 Unspecified mycosis	0.264	0.736	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.263	0.737	0.000
B33 Other viral diseases, not elsewhere classified	0.263	0.737	0.000
M50 Cervical disk disorders	0.263	0.737	0.000
M50.1 Cervical disk disorder with radiculopathy	0.263	0.737	0.000
M65-M68 Disorders of synovium and tendon	0.263	0.737	0.000
B36 Other superficial mycoses	0.262	0.738	0.000
E07.9 Disorder of thyroid, unspecified	0.262	0.738	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.262	0.738	0.000
B25.9 Cytomegaloviral disease, unspecified	0.260	0.740	0.000
A15-A19 Tuberculosis	0.260	0.740	0.000
K70.1 Alcoholic hepatitis	0.260	0.740	0.000
M00-M03 Infectious arthropathies	0.260	0.740	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.259	0.741	0.000
G12.2 Motor neuron disease	0.258	0.742	0.000
K35-K38 Diseases of appendix	0.258	0.742	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.258	0.742	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.258	0.742	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.256	0.744	0.000
A75-A79 Rickettsioses	0.256	0.744	0.000
A70-A74 Other diseases caused by chlamydiae	0.256	0.744	0.000
A20-A28 Certain zoonotic bacterial diseases	0.256	0.744	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.256	0.744	0.000
M12 Other specific arthropathies	0.256	0.744	0.000
M89.8 Other specified disorders of bone	0.256	0.744	0.000
B06 Rubella [German measles]	0.255	0.745	0.000
B05 Measles	0.255	0.745	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.255	0.745	0.000
B04 Monkeypox	0.255	0.745	0.000
B03 Smallpox	0.255	0.745	0.000
B48 Other mycoses, not elsewhere classified	0.255	0.745	0.000
B47 Mycetoma	0.255	0.745	0.000
B46 Zygomycosis	0.255	0.745	0.000
B45 Cryptococcosis	0.255	0.745	0.000
B43 Chromomycosis and phaeomycotic abscess	0.255	0.745	0.000
B42 Sporotrichosis	0.255	0.745	0.000
B41 Paracoccidioidomycosis	0.255	0.745	0.000
B40 Blastomycosis	0.255	0.745	0.000
B39 Histoplasmosis	0.255	0.745	0.000
B38 Coccidioidomycosis	0.255	0.745	0.000
B01 Varicella [chickenpox]	0.255	0.745	0.000
H34.0 Transient retinal artery occlusion	0.254	0.746	0.000
B02.8 Zoster with other complications	0.254	0.746	0.000
B02.7 Disseminated zoster	0.254	0.746	0.000
B02.1 Zoster meningitis	0.254	0.746	0.000
B02.0 Zoster encephalitis	0.254	0.746	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.253	0.746	0.000
M60 Myositis	0.253	0.747	0.000
M33.1 Other dermatomyositis	0.253	0.747	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.253	0.747	0.000
M14 Arthropathies in other diseases classified elsewhere	0.253	0.747	0.000
G56.8 Other mononeuropathies of upper limb	0.252	0.748	0.000
M08 Juvenile arthritis	0.252	0.748	0.000
G54.6 Phantom limb syndrome with pain	0.252	0.748	0.000
B34 Viral infection of unspecified site	0.252	0.748	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.250	0.750	0.000
B37.6 Candidal endocarditis	0.250	0.750	0.000
B37.5 Candidal meningitis	0.250	0.750	0.000
M89.3 Hypertrophy of bone	0.250	0.750	0.000
B37.9 Candidiasis, unspecified	0.249	0.750	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations