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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2517887
log Bayes Factor = 18.2597
Chromosome 6   position 29,807,393  (GRCh37) Explore rs2517887 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.013 0.987
E83 Disorders of mineral metabolism
0.000 0.110 0.890
E70-E90 Metabolic disorders
0.000 0.120 0.880
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.122 0.878
E89.0 Postprocedural hypothyroidism
0.000 0.125 0.875
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.140 0.860
L40.8 Other psoriasis
0.000 0.141 0.859
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.145 0.855
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.147 0.853
E00-E07 Disorders of thyroid gland
0.000 0.148 0.852
E05.9 Thyrotoxicosis, unspecified
0.000 0.151 0.849
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.155 0.845
E16 Other disorders of pancreatic internal secretion
0.000 0.162 0.838
E16.2 Hypoglycaemia, unspecified
0.000 0.164 0.836
E85 Amyloidosis
0.000 0.207 0.793
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.249 0.751
E89.2 Postprocedural hypoparathyroidism
0.000 0.274 0.726
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.328 0.671
E85.9 Amyloidosis, unspecified
0.000 0.332 0.668
E03 Other hypothyroidism
0.000 0.338 0.662
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.342 0.658
E80.4 Gilbert's syndrome
0.000 0.342 0.658
E85.4 Organ-limited amyloidosis
0.000 0.344 0.656
E89.3 Postprocedural hypopituitarism
0.000 0.360 0.640
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.362 0.638
E83.8 Other disorders of mineral metabolism
0.000 0.362 0.638
E83.2 Disorders of zinc metabolism
0.000 0.362 0.638
E83.0 Disorders of copper metabolism
0.000 0.362 0.638
E84 Cystic fibrosis
0.000 0.369 0.631
E79 Disorders of purine and pyrimidine metabolism
0.000 0.369 0.631
E77 Disorders of glycoprotein metabolism
0.000 0.369 0.631
E76 Disorders of glycosaminoglycan metabolism
0.000 0.369 0.631
E72 Other disorders of amino-acid metabolism
0.000 0.369 0.631
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.369 0.631
E70 Disorders of aromatic amino-acid metabolism
0.000 0.369 0.631
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.369 0.631
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.371 0.629
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.371 0.629
E89.5 Postprocedural testicular hypofunction
0.000 0.371 0.629
E89.1 Postprocedural hypoinsulinaemia
0.000 0.371 0.629
E89.4 Postprocedural ovarian failure
0.000 0.372 0.627
E05.8 Other thyrotoxicosis
0.000 0.383 0.617
E05.5 Thyroid crisis or storm
0.000 0.384 0.616
E05.4 Thyrotoxicosis factitia
0.000 0.384 0.616
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.384 0.616
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.384 0.616
E73 Lactose intolerance
0.000 0.388 0.611
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.389 0.611
E00 Congenital iodine-deficiency syndrome
0.000 0.389 0.611
E85.3 Secondary systemic amyloidosis
0.000 0.393 0.607
E15 Nondiabetic hypoglycaemic coma
0.000 0.394 0.606
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.399 0.601
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.399 0.601
E16.4 Abnormal secretion of gastrin
0.000 0.399 0.601
E16.3 Increased secretion of glucagon
0.000 0.399 0.601
E74 Other disorders of carbohydrate metabolism
0.000 0.405 0.595
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.409 0.590
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.411 0.589
L40.0 Psoriasis vulgaris
0.000 0.411 0.589
E16.1 Other hypoglycaemia
0.000 0.427 0.573
E83.3 Disorders of phosphorus metabolism
0.000 0.429 0.571
E03.9 Hypothyroidism, unspecified
0.000 0.429 0.571
E85.8 Other amyloidosis
0.000 0.432 0.568
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.432 0.568
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.432 0.568
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.432 0.568
E06 Thyroiditis
0.000 0.433 0.567
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.443 0.557
E80.6 Other disorders of bilirubin metabolism
0.000 0.455 0.545
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.461 0.539
E80.5 Crigler-Najjar syndrome
0.000 0.461 0.539
E80.3 Defects of catalase and peroxydase
0.000 0.461 0.539
E80.1 Porphyria cutanea tarda
0.000 0.461 0.539
E80.0 Hereditary erythropoietic porphyria
0.000 0.461 0.539
E80.2 Other porphyria
0.000 0.466 0.534
E40-E46 Malnutrition
0.000 0.466 0.534
E03.8 Other specified hypothyroidism
0.000 0.483 0.516
E07 Other disorders of thyroid
0.000 0.521 0.478
E03.5 Myxoedema coma
0.000 0.525 0.474
E03.4 Atrophy of thyroid (acquired)
0.000 0.525 0.474
E03.3 Postinfectious hypothyroidism
0.000 0.525 0.474
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.525 0.474
K90 Intestinal malabsorption
0.000 0.526 0.474
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.547 0.452
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.547 0.452
E70.3 Albinism
0.000 0.547 0.452
E70.2 Disorders of tyrosine metabolism
0.000 0.547 0.452
E70.1 Other hyperphenylalaninaemias
0.000 0.547 0.452
E70.0 Classical phenylketonuria
0.000 0.547 0.452
E71.3 Disorders of fatty-acid metabolism
0.000 0.547 0.452
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.547 0.452
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.547 0.452
E71.0 Maple-syrup-urine disease
0.000 0.547 0.452
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.547 0.452
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.547 0.452
E72.5 Disorders of glycine metabolism
0.000 0.547 0.452
E72.4 Disorders of ornithine metabolism
0.000 0.547 0.452
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.547 0.452
E72.2 Disorders of urea cycle metabolism
0.000 0.547 0.452
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.547 0.452
E72.0 Disorders of amino-acid transport
0.000 0.547 0.452
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.547 0.452
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.547 0.452
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.547 0.452
E76.2 Other mucopolysaccharidoses
0.000 0.547 0.452
E76.1 Mucopolysaccharidosis, type II
0.000 0.547 0.452
E76.0 Mucopolysaccharidosis, type I
0.000 0.547 0.452
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.547 0.452
E77.8 Other disorders of glycoprotein metabolism
0.000 0.547 0.452
E77.1 Defects in glycoprotein degradation
0.000 0.547 0.452
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.547 0.452
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.547 0.452
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.547 0.452
E79.1 Lesch-Nyhan syndrome
0.000 0.547 0.452
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.547 0.452
E84.9 Cystic fibrosis, unspecified
0.000 0.547 0.452
E84.8 Cystic fibrosis with other manifestations
0.000 0.547 0.452
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.547 0.452
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.547 0.452
E65-E68 Obesity and other hyperalimentation
0.000 0.556 0.443
E73.8 Other lactose intolerance
0.000 0.561 0.438
E73.1 Secondary lactase deficiency
0.000 0.561 0.438
E73.0 Congenital lactase deficiency
0.000 0.561 0.438
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.562 0.438
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.562 0.438
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.562 0.438
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.562 0.438
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.562 0.438
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.562 0.438
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.562 0.438
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.562 0.438
E03.1 Congenital hypothyroidism without goitre
0.000 0.566 0.434
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.568 0.432
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.573 0.427
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.573 0.427
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.573 0.427
E74.2 Disorders of galactose metabolism
0.000 0.573 0.427
E74.1 Disorders of fructose metabolism
0.000 0.573 0.427
E74.0 Glycogen storage disease
0.000 0.573 0.427
E75.6 Lipid storage disorder, unspecified
0.000 0.576 0.423
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.576 0.423
E75.3 Sphingolipidosis, unspecified
0.000 0.576 0.423
E75.2 Other sphingolipidosis
0.000 0.576 0.423
E75.1 Other gangliosidosis
0.000 0.576 0.423
E75.0 GM2 gangliosidosis
0.000 0.576 0.423
E88 Other metabolic disorders
0.000 0.578 0.421
E73.9 Lactose intolerance, unspecified
0.000 0.581 0.419
K90.9 Intestinal malabsorption, unspecified
0.000 0.584 0.415
E06.9 Thyroiditis, unspecified
0.000 0.587 0.413
L40-L45 Papulosquamous disorders
0.000 0.589 0.411
E06.4 Drug-induced thyroiditis
0.000 0.593 0.407
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.593 0.407
E06.1 Subacute thyroiditis
0.000 0.593 0.407
E06.0 Acute thyroiditis
0.000 0.593 0.407
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.609 0.391
E06.5 Other chronic thyroiditis
0.000 0.612 0.388
E83.4 Disorders of magnesium metabolism
0.000 0.613 0.387
E75.5 Other lipid storage disorders
0.000 0.617 0.383
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.617 0.383
E45 Retarded development following protein-energy malnutrition
0.000 0.617 0.383
E43 Unspecified severe protein-energy malnutrition
0.000 0.617 0.383
E42 Marasmic kwashiorkor
0.000 0.617 0.383
E41 Nutritional marasmus
0.000 0.617 0.383
E40 Kwashiorkor
0.000 0.617 0.383
E06.3 Autoimmune thyroiditis
0.000 0.623 0.377
E50-E64 Other nutritional deficiencies
0.000 0.625 0.375
E10-E14 Diabetes mellitus
0.000 0.636 0.364
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.638 0.361
E07.1 Dyshormogenetic goitre
0.000 0.657 0.343
E07.0 Hypersecretion of calcitonin
0.000 0.657 0.343
K90.3 Pancreatic steatorrhoea
0.000 0.660 0.340
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.660 0.340
K90.1 Tropical sprue
0.000 0.660 0.340
E65 Localised adiposity
0.000 0.666 0.334
E07.9 Disorder of thyroid, unspecified
0.000 0.681 0.319
E67 Other hyperalimentation
0.000 0.682 0.318
E68 Sequelae of hyperalimentation
0.000 0.682 0.318
L43 Lichen planus
0.000 0.691 0.309
E46 Unspecified protein-energy malnutrition
0.000 0.696 0.304
E88.9 Metabolic disorder, unspecified
0.000 0.698 0.302
K90.8 Other intestinal malabsorption
0.000 0.699 0.300
L44 Other papulosquamous disorders
0.000 0.705 0.295
L41 Parapsoriasis
0.000 0.705 0.295
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.705 0.295
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.706 0.294
E88.3 Tumour lysis syndrome
0.000 0.707 0.293
E88.8 Other specified metabolic disorders
0.000 0.708 0.292
E44.1 Mild protein-energy malnutrition
0.000 0.725 0.275
E44.0 Moderate protein-energy malnutrition
0.000 0.725 0.275
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.731 0.269
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.731 0.269
E63 Other nutritional deficiencies
0.000 0.731 0.269
E56 Other vitamin deficiencies
0.000 0.731 0.269
E51 Thiamine deficiency
0.000 0.731 0.269
E50 Vitamin A deficiency
0.000 0.731 0.269
E60 Dietary zinc deficiency
0.000 0.731 0.269
E59 Dietary selenium deficiency
0.000 0.731 0.269
E58 Dietary calcium deficiency
0.000 0.731 0.269
E54 Ascorbic acid deficiency
0.000 0.731 0.269
E52 Niacin deficiency [pellagra]
0.000 0.731 0.269
L42 Pityriasis rosea
0.000 0.733 0.267
E12 Malnutrition-related diabetes mellitus
0.000 0.739 0.261
E10 Insulin-dependent diabetes mellitus
0.000 0.744 0.256
E88.2 Lipomatosis, not elsewhere classified
0.000 0.748 0.252
E07.8 Other specified disorders of thyroid
0.000 0.749 0.250
L43.9 Lichen planus, unspecified
0.000 0.755 0.245
E11 Non-insulin-dependent diabetes mellitus
0.000 0.762 0.238
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.763 0.237
E11.3 With ophthalmic complications
0.000 0.768 0.232
E67.8 Other specified hyperalimentation
0.000 0.772 0.228
E67.3 Hypervitaminosis D
0.000 0.772 0.228
E67.2 Megavitamin-B6 syndrome
0.000 0.772 0.228
E67.1 Hypercarotenaemia
0.000 0.772 0.228
E67.0 Hypervitaminosis A
0.000 0.772 0.228
E53 Deficiency of other B group vitamins
0.000 0.776 0.224
L43.3 Subacute (active) lichen planus
0.000 0.778 0.222
L43.2 Lichenoid drug reaction
0.000 0.778 0.222
L43.1 Bullous lichen planus
0.000 0.778 0.222
L43.0 Hypertrophic lichen planus
0.000 0.778 0.222
E10.1 With ketoacidosis
0.000 0.779 0.221
E83.5 Disorders of calcium metabolism
0.000 0.781 0.219
E61 Deficiency of other nutrient elements
0.000 0.783 0.216
E55 Vitamin D deficiency
0.000 0.786 0.214
E13 Other specified diabetes mellitus
0.000 0.787 0.213
L41.9 Parapsoriasis, unspecified
0.000 0.788 0.211
L41.8 Other parapsoriasis
0.000 0.788 0.211
L41.5 Retiform parapsoriasis
0.000 0.788 0.211
L41.4 Large plaque parapsoriasis
0.000 0.788 0.211
L41.3 Small plaque parapsoriasis
0.000 0.788 0.211
L41.2 Lymphomatoid papulosis
0.000 0.788 0.211
L41.1 Pityriasis lichenoides chronica
0.000 0.788 0.211
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.788 0.211
L44.9 Papulosquamous disorder, unspecified
0.000 0.788 0.211
L44.8 Other specified papulosquamous disorders
0.000 0.788 0.211
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.788 0.211
L44.3 Lichen ruber moniliformis
0.000 0.788 0.211
L44.2 Lichen striatus
0.000 0.788 0.211
L44.1 Lichen nitidus
0.000 0.788 0.211
L44.0 Pityriasis rubra pilaris
0.000 0.788 0.211
L43.8 Other lichen planus
0.000 0.789 0.211
E10.4 With neurological complications
0.000 0.792 0.208
E10.6 With other specified complications
0.000 0.796 0.204
E11.5 With peripheral circulatory complications
0.000 0.804 0.196
E50.9 Vitamin A deficiency, unspecified
0.000 0.807 0.193
E50.8 Other manifestations of vitamin A deficiency
0.000 0.807 0.193
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.807 0.193
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.807 0.193
E50.5 Vitamin A deficiency with night blindness
0.000 0.807 0.193
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.807 0.193
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.807 0.193
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.807 0.193
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.807 0.193
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.807 0.193
E51.9 Thiamine deficiency, unspecified
0.000 0.807 0.193
E51.8 Other manifestations of thiamine deficiency
0.000 0.807 0.193
E51.2 Wernicke's encephalopathy
0.000 0.807 0.193
E51.1 Beriberi
0.000 0.807 0.193
E56.9 Vitamin deficiency, unspecified
0.000 0.807 0.193
E56.8 Deficiency of other vitamins
0.000 0.807 0.193
E56.1 Deficiency of vitamin K
0.000 0.807 0.193
E56.0 Deficiency of vitamin E
0.000 0.807 0.193
E63.9 Nutritional deficiency, unspecified
0.000 0.807 0.193
E63.8 Other specified nutritional deficiencies
0.000 0.807 0.193
E63.1 Imbalance of constituents of food intake
0.000 0.807 0.193
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.807 0.193
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.807 0.193
E64.8 Sequelae of other nutritional deficiencies
0.000 0.807 0.193
E64.3 Sequelae of rickets
0.000 0.807 0.193
E64.2 Sequelae of vitamin C deficiency
0.000 0.807 0.193
E64.1 Sequelae of vitamin A deficiency
0.000 0.807 0.193
E64.0 Sequelae of protein-energy malnutrition
0.000 0.807 0.193
E10.5 With peripheral circulatory complications
0.000 0.810 0.190
E04 Other non-toxic goitre
0.000 0.810 0.190
E10.2 With renal complications
0.000 0.811 0.189
E12.9 Without complications
0.000 0.813 0.187
E12.8 With unspecified complications
0.000 0.813 0.187
E12.7 With multiple complications
0.000 0.813 0.187
E12.6 With other specified complications
0.000 0.813 0.187
E12.5 With peripheral circulatory complications
0.000 0.813 0.187
E12.4 With neurological complications
0.000 0.813 0.187
E12.3 With ophthalmic complications
0.000 0.813 0.187
E12.2 With renal complications
0.000 0.813 0.187
E12.1 With ketoacidosis
0.000 0.813 0.187
E12.0 With coma
0.000 0.813 0.187
E11.1 With ketoacidosis
0.000 0.813 0.186
E10.7 With multiple complications
0.000 0.816 0.184
E10.0 With coma
0.000 0.817 0.183
E10.8 With unspecified complications
0.000 0.823 0.177
E14 Unspecified diabetes mellitus
0.000 0.824 0.175
E11.7 With multiple complications
0.000 0.829 0.171
E53.9 Vitamin B deficiency, unspecified
0.000 0.836 0.164
E53.1 Pyridoxine deficiency
0.000 0.839 0.161
E53.0 Riboflavin deficiency
0.000 0.839 0.161
E11.8 With unspecified complications
0.000 0.841 0.159
E61.9 Deficiency of nutrient element, unspecified
0.000 0.844 0.155
E61.8 Deficiency of other specified nutrient elements
0.000 0.844 0.155
E61.7 Deficiency of multiple nutrient elements
0.000 0.844 0.155
E61.6 Vanadium deficiency
0.000 0.844 0.155
E61.5 Molybdenum deficiency
0.000 0.844 0.155
E61.4 Chromium deficiency
0.000 0.844 0.155
E61.3 Manganese deficiency
0.000 0.844 0.155
E61.2 Magnesium deficiency
0.000 0.844 0.155
E61.0 Copper deficiency
0.000 0.844 0.155
E55.0 Rickets, active
0.000 0.846 0.153
E13.8 With unspecified complications
0.000 0.847 0.153
E13.7 With multiple complications
0.000 0.847 0.153
E13.6 With other specified complications
0.000 0.847 0.153
E13.5 With peripheral circulatory complications
0.000 0.847 0.153
E13.4 With neurological complications
0.000 0.847 0.153
E13.3 With ophthalmic complications
0.000 0.847 0.153
E13.2 With renal complications
0.000 0.847 0.153
E13.1 With ketoacidosis
0.000 0.847 0.153
E13.0 With coma
0.000 0.847 0.153
E10.3 With ophthalmic complications
0.000 0.852 0.148
E11.4 With neurological complications
0.000 0.856 0.144
E14.3 With ophthalmic complications
0.000 0.858 0.142
E04.0 Non-toxic diffuse goitre
0.000 0.861 0.138
E04.8 Other specified non-toxic goitre
0.000 0.864 0.136
E11.0 With coma
0.000 0.864 0.136
E11.6 With other specified complications
0.000 0.865 0.135
E14.8 With unspecified complications
0.000 0.867 0.133
E14.4 With neurological complications
0.000 0.873 0.126
E14.7 With multiple complications
0.000 0.874 0.126
E14.6 With other specified complications
0.000 0.874 0.126
E14.0 With coma
0.000 0.874 0.126
E14.1 With ketoacidosis
0.000 0.874 0.125
E14.5 With peripheral circulatory complications
0.000 0.875 0.125
E11.2 With renal complications
0.000 0.884 0.116
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.885 0.115
E14.2 Withrenal complications
0.000 0.890 0.110
E53.8 Deficiency of other specified B group vitamins
0.000 0.890 0.110
E04.9 Non-toxic goitre, unspecified
0.000 0.890 0.110
E66 Obesity
0.000 0.894 0.106
E13.9 Without complications
0.000 0.895 0.105
E61.1 Iron deficiency
0.000 0.897 0.103
E55.9 Vitamin D deficiency, unspecified
0.000 0.902 0.098
E78.8 Other disorders of lipoprotein metabolism
0.000 0.904 0.096
E78.6 Lipoprotein deficiency
0.000 0.912 0.088
E78.3 Hyperchylomicronaemia
0.000 0.917 0.082
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.919 0.081
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.919 0.081
E78.4 Other hyperlipidaemia
0.000 0.922 0.078
E66.1 Drug-induced obesity
0.000 0.924 0.076
E04.1 Non-toxic single thyroid nodule
0.000 0.930 0.070
E66.0 Obesity due to excess calories
0.000 0.934 0.065
E78.2 Mixed hyperlipidaemia
0.000 0.938 0.062
E78.1 Pure hyperglyceridaemia
0.000 0.940 0.060
E20-E35 Disorders of other endocrine glands
0.000 0.957 0.042
E66.8 Other obesity
0.000 0.958 0.042
E04.2 Non-toxic multinodular goitre
0.000 0.960 0.040
E34 Other endocrine disorders
0.000 0.966 0.033
K90-K93 Other diseases of the digestive system
0.000 0.968 0.032
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.969 0.030
E32 Diseases of thymus
0.000 0.969 0.030
E31 Polyglandular dysfunction
0.000 0.969 0.030
E30 Disorders of puberty, not elsewhere classified
0.000 0.969 0.030
E34.9 Endocrine disorder, unspecified
0.000 0.969 0.031
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.970 0.030
E26 Hyperaldosteronism
0.000 0.970 0.030
E20 Hypoparathyroidism
0.000 0.971 0.029
E25 Adrenogenital disorders
0.000 0.971 0.028
E24 Cushing's syndrome
0.000 0.971 0.028
E29 Testicular dysfunction
0.000 0.973 0.027
E10.9 Without complications
0.000 0.973 0.027
M07.3 Other psoriatic arthropathies
0.000 0.975 0.025
E34.5 Androgen resistance syndrome
0.000 0.976 0.024
E34.4 Constitutional tall stature
0.000 0.976 0.024
E34.3 Short stature, not elsewhere classified
0.000 0.976 0.024
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.976 0.024
E34.1 Other hypersecretion of intestinal hormones
0.000 0.976 0.024
E28 Ovarian dysfunction
0.001 0.976 0.023
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.977 0.023
E22 Hyperfunction of pituitary gland
0.000 0.977 0.023
E30.9 Disorder of puberty, unspecified
0.000 0.978 0.022
E30.8 Other disorders of puberty
0.000 0.978 0.022
E30.1 Precocious puberty
0.000 0.978 0.022
E30.0 Delayed puberty
0.000 0.978 0.022
E31.9 Polyglandular dysfunction, unspecified
0.000 0.978 0.022
E31.8 Other polyglandular dysfunction
0.000 0.978 0.022
E31.1 Polyglandular hyperfunction
0.000 0.978 0.022
E31.0 Autoimmune polyglandular failure
0.000 0.978 0.022
E32.9 Disease of thymus, unspecified
0.000 0.978 0.022
E32.8 Other diseases of thymus
0.000 0.978 0.022
E32.1 Abscess of thymus
0.000 0.978 0.022
E32.0 Persistent hyperplasia of thymus
0.000 0.978 0.022
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.978 0.022
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.978 0.022
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.978 0.022
E26.9 Hyperaldosteronism, unspecified
0.000 0.978 0.021
E26.8 Other hyperaldosteronism
0.000 0.978 0.021
E26.1 Secondary hyperaldosteronism
0.000 0.978 0.021
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.978 0.022
E34.0 Carcinoid syndrome
0.000 0.979 0.021
E20.8 Other hypoparathyroidism
0.000 0.979 0.021
E20.1 Pseudohypoparathyroidism
0.000 0.979 0.021
E20.0 Idiopathic hypoparathyroidism
0.000 0.979 0.021
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.979 0.021
E26.0 Primary hyperaldosteronism
0.000 0.979 0.021
E25.9 Adrenogenital disorder, unspecified
0.000 0.979 0.021
E25.8 Other adrenogenital disorders
0.000 0.979 0.021
E24.8 Other Cushing's syndrome
0.000 0.979 0.020
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.979 0.020
E24.3 Ectopic ACTH syndrome
0.000 0.979 0.020
E24.1 Nelson's syndrome
0.000 0.979 0.020
E24.9 Cushing's syndrome, unspecified
0.000 0.979 0.020
L20-L30 Dermatitis and eczema
0.000 0.980 0.020
E34.8 Other specified endocrine disorders
0.000 0.980 0.020
E24.0 Pituitary-dependent Cushing's disease
0.000 0.980 0.020
M07 Psoriatic and enteropathic arthropathies
0.000 0.980 0.020
E27 Other disorders of adrenal gland
0.000 0.980 0.019
E20.9 Hypoparathyroidism, unspecified
0.000 0.980 0.019
E24.2 Drug-induced Cushing's syndrome
0.000 0.980 0.019
E29.9 Testicular dysfunction, unspecified
0.000 0.980 0.019
E29.8 Other testicular dysfunction
0.000 0.980 0.019
E29.0 Testicular hyperfunction
0.000 0.980 0.019
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.980 0.019
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.980 0.019
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.981 0.019
L28 Lichen simplex chronicus and prurigo
0.000 0.981 0.019
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.981 0.019
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.981 0.019
E78.5 Hyperlipidaemia, unspecified
0.000 0.981 0.019
E28.3 Primary ovarian failure
0.001 0.981 0.018
M07.38 Other psoriatic arthropathies (Other)
0.000 0.982 0.018
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.982 0.018
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.982 0.018
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.982 0.018
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.982 0.018
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.982 0.018
L30 Other dermatitis
0.000 0.982 0.018
L28.0 Lichen simplex chronicus
0.000 0.982 0.018
E86 Volume depletion
0.000 0.982 0.017
M06.9 Rheumatoid arthritis, unspecified
0.000 0.982 0.018
L27 Dermatitis due to substances taken internally
0.000 0.983 0.017
L10-L14 Bullous disorders
0.000 0.983 0.017
L30.9 Dermatitis, unspecified
0.000 0.983 0.017
E28.9 Ovarian dysfunction, unspecified
0.001 0.983 0.016
E28.8 Other ovarian dysfunction
0.001 0.983 0.016
E28.1 Androgen excess
0.001 0.983 0.016
E28.0 Oestrogen excess
0.001 0.983 0.016
M06 Other rheumatoid arthritis
0.000 0.983 0.017
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.983 0.017
K93.1 Megacolon in Chagas' disease
0.000 0.983 0.017
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.983 0.017
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.983 0.017
E22.8 Other hyperfunction of pituitary gland
0.000 0.983 0.017
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.984 0.016
E27.2 Addisonian crisis
0.000 0.984 0.016
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.984 0.016
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.016 0.984 0.000
M05-M14 Inflammatory polyarthropathies
0.000 0.984 0.016
L21 Seborrhoeic dermatitis
0.000 0.984 0.016
E29.1 Testicular hypofunction
0.000 0.984 0.015
E27.1 Primary adrenocortical insufficiency
0.000 0.984 0.015
E23 Hypofunction and other disorders of pituitary gland
0.000 0.985 0.015
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.985 0.015
N42.1 Congestion and haemorrhage of prostate
0.015 0.985 0.000
L28.1 Prurigo nodularis
0.000 0.985 0.015
L24 Irritant contact dermatitis
0.000 0.985 0.015
L26 Exfoliative dermatitis
0.000 0.985 0.015
L22 Diaper [napkin] dermatitis
0.000 0.985 0.015
M06.3 Rheumatoid nodule
0.000 0.985 0.015
L13 Other bullous disorders
0.000 0.985 0.014
M07.6 Other enteropathic arthropathies
0.000 0.986 0.014
M07.5 Arthropathy in ulcerative colitis
0.000 0.986 0.014
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.986 0.014
M07.2 Psoriatic spondylitis
0.000 0.986 0.014
M07.1 Arthritis mutilans
0.000 0.986 0.014
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.986 0.014
E27.5 Adrenomedullary hyperfunction
0.000 0.986 0.014
E27.0 Other adrenocortical overactivity
0.000 0.986 0.014
L29 Pruritus
0.000 0.986 0.014
L30.8 Other specified dermatitis
0.000 0.986 0.014
L28.2 Other prurigo
0.000 0.986 0.014
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.987 0.013
E27.8 Other specified disorders of adrenal gland
0.000 0.987 0.013
L30.5 Pityriasis alba
0.000 0.987 0.013
L30.2 Cutaneous autosensitisation
0.000 0.987 0.013
L30.1 Dyshidrosis [pompholyx]
0.000 0.987 0.013
L30.0 Nummular dermatitis
0.000 0.987 0.013
M06.4 Inflammatory polyarthropathy
0.000 0.987 0.013
L25 Unspecified contact dermatitis
0.000 0.987 0.013
L50-L54 Urticaria and erythema
0.000 0.987 0.013
L12 Pemphigoid
0.000 0.987 0.013
M05 Seropositive rheumatoid arthritis
0.000 0.987 0.013
L23 Allergic contact dermatitis
0.000 0.987 0.013
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.987 0.013
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.987 0.013
L27.8 Dermatitis due to other substances taken internally
0.000 0.987 0.013
L10 Pemphigus
0.000 0.987 0.013
L14 Bullous disorders in diseases classified elsewhere
0.000 0.987 0.013
M10 Gout
0.000 0.987 0.013
L20 Atopic dermatitis
0.000 0.987 0.012

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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