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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2517898
log Bayes Factor = 22.5173
Chromosome 6   position 29,799,746  (GRCh37) Explore rs2517898 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.002 0.998
L40 Psoriasis
0.000 0.002 0.998
E16 Other disorders of pancreatic internal secretion
0.000 0.002 0.998
E16.2 Hypoglycaemia, unspecified
0.000 0.003 0.997
E70-E90 Metabolic disorders
0.000 0.007 0.993
E10.9 Without complications
0.000 0.008 0.992
E83 Disorders of mineral metabolism
0.000 0.009 0.991
E10.3 With ophthalmic complications
0.000 0.040 0.960
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.045 0.955
E00-E07 Disorders of thyroid gland
0.000 0.046 0.954
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.052 0.948
E05.9 Thyrotoxicosis, unspecified
0.000 0.054 0.946
E10.1 With ketoacidosis
0.000 0.062 0.938
E10.4 With neurological complications
0.000 0.063 0.937
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.065 0.935
E89.0 Postprocedural hypothyroidism
0.000 0.084 0.916
N40 Hyperplasia of prostate
0.912 0.088 0.000
E10.6 With other specified complications
0.000 0.152 0.848
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.154 0.846
E10.5 With peripheral circulatory complications
0.000 0.162 0.838
E10.0 With coma
0.000 0.186 0.814
E85 Amyloidosis
0.000 0.188 0.812
L40.1 Generalised pustular psoriasis
0.000 0.214 0.786
E89.2 Postprocedural hypoparathyroidism
0.000 0.236 0.764
L40.8 Other psoriasis
0.000 0.237 0.763
E10.2 With renal complications
0.000 0.244 0.756
E80.4 Gilbert's syndrome
0.000 0.262 0.738
L40.3 Pustulosis palmaris et plantaris
0.000 0.264 0.736
E05.8 Other thyrotoxicosis
0.000 0.265 0.735
E79 Disorders of purine and pyrimidine metabolism
0.000 0.265 0.735
E89.4 Postprocedural ovarian failure
0.000 0.275 0.725
E16.1 Other hypoglycaemia
0.000 0.277 0.723
E73 Lactose intolerance
0.000 0.278 0.722
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.279 0.721
L40.0 Psoriasis vulgaris
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.285 0.715
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.285 0.715
E16.4 Abnormal secretion of gastrin
0.000 0.285 0.715
E16.3 Increased secretion of glucagon
0.000 0.285 0.715
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.287 0.713
E74 Other disorders of carbohydrate metabolism
0.000 0.288 0.712
E77 Disorders of glycoprotein metabolism
0.000 0.288 0.712
E76 Disorders of glycosaminoglycan metabolism
0.000 0.288 0.712
E72 Other disorders of amino-acid metabolism
0.000 0.288 0.712
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.288 0.712
E70 Disorders of aromatic amino-acid metabolism
0.000 0.288 0.712
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.288 0.712
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.289 0.711
E83.8 Other disorders of mineral metabolism
0.000 0.289 0.711
E83.2 Disorders of zinc metabolism
0.000 0.289 0.711
E83.0 Disorders of copper metabolism
0.000 0.289 0.711
E84 Cystic fibrosis
0.000 0.296 0.704
E10.8 With unspecified complications
0.000 0.306 0.694
E85.9 Amyloidosis, unspecified
0.000 0.308 0.692
E89.3 Postprocedural hypopituitarism
0.000 0.311 0.689
E05.5 Thyroid crisis or storm
0.000 0.315 0.685
E05.4 Thyrotoxicosis factitia
0.000 0.315 0.685
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.315 0.685
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.315 0.685
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.316 0.684
E00 Congenital iodine-deficiency syndrome
0.000 0.316 0.684
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.320 0.680
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.320 0.680
E89.5 Postprocedural testicular hypofunction
0.000 0.320 0.680
L40.4 Guttate psoriasis
0.000 0.322 0.678
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.324 0.676
E11 Non-insulin-dependent diabetes mellitus
0.000 0.333 0.667
E14 Unspecified diabetes mellitus
0.000 0.334 0.666
E40-E46 Malnutrition
0.000 0.365 0.635
E13 Other specified diabetes mellitus
0.000 0.369 0.631
E11.3 With ophthalmic complications
0.000 0.371 0.629
E80.1 Porphyria cutanea tarda
0.000 0.378 0.622
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.389 0.611
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.394 0.606
E80.5 Crigler-Najjar syndrome
0.000 0.394 0.606
E80.3 Defects of catalase and peroxydase
0.000 0.394 0.606
E80.2 Other porphyria
0.000 0.394 0.606
E80.0 Hereditary erythropoietic porphyria
0.000 0.394 0.606
E88 Other metabolic disorders
0.000 0.394 0.605
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.404 0.596
E80.6 Other disorders of bilirubin metabolism
0.000 0.405 0.595
E14.3 With ophthalmic complications
0.000 0.406 0.594
E85.4 Organ-limited amyloidosis
0.000 0.407 0.592
E89.1 Postprocedural hypoinsulinaemia
0.000 0.411 0.588
E85.3 Secondary systemic amyloidosis
0.000 0.417 0.583
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.418 0.582
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.418 0.582
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.418 0.582
E85.8 Other amyloidosis
0.000 0.447 0.553
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.449 0.551
E73.9 Lactose intolerance, unspecified
0.000 0.472 0.528
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.473 0.527
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.473 0.527
E79.1 Lesch-Nyhan syndrome
0.000 0.473 0.527
E73.8 Other lactose intolerance
0.000 0.482 0.518
E73.1 Secondary lactase deficiency
0.000 0.482 0.518
E73.0 Congenital lactase deficiency
0.000 0.482 0.518
E65-E68 Obesity and other hyperalimentation
0.000 0.483 0.517
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.489 0.511
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.489 0.511
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.489 0.511
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.489 0.511
E74.2 Disorders of galactose metabolism
0.000 0.489 0.511
E74.1 Disorders of fructose metabolism
0.000 0.489 0.511
E74.0 Glycogen storage disease
0.000 0.489 0.511
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.490 0.510
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.490 0.510
E70.3 Albinism
0.000 0.490 0.510
E70.2 Disorders of tyrosine metabolism
0.000 0.490 0.510
E70.1 Other hyperphenylalaninaemias
0.000 0.490 0.510
E70.0 Classical phenylketonuria
0.000 0.490 0.510
E71.3 Disorders of fatty-acid metabolism
0.000 0.490 0.510
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.490 0.510
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.490 0.510
E71.0 Maple-syrup-urine disease
0.000 0.490 0.510
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.490 0.510
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.490 0.510
E72.5 Disorders of glycine metabolism
0.000 0.490 0.510
E72.4 Disorders of ornithine metabolism
0.000 0.490 0.510
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.490 0.510
E72.2 Disorders of urea cycle metabolism
0.000 0.490 0.510
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.490 0.510
E72.0 Disorders of amino-acid transport
0.000 0.490 0.510
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.490 0.510
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.490 0.510
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.490 0.510
E76.2 Other mucopolysaccharidoses
0.000 0.490 0.510
E76.1 Mucopolysaccharidosis, type II
0.000 0.490 0.510
E76.0 Mucopolysaccharidosis, type I
0.000 0.490 0.510
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.490 0.510
E77.8 Other disorders of glycoprotein metabolism
0.000 0.490 0.510
E77.1 Defects in glycoprotein degradation
0.000 0.490 0.510
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.490 0.510
E14.5 With peripheral circulatory complications
0.000 0.492 0.508
E84.8 Cystic fibrosis with other manifestations
0.000 0.495 0.505
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.495 0.505
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.495 0.505
E84.9 Cystic fibrosis, unspecified
0.000 0.502 0.497
E11.4 With neurological complications
0.000 0.503 0.497
E11.1 With ketoacidosis
0.000 0.505 0.495
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.509 0.491
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.509 0.491
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.509 0.491
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.509 0.491
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.509 0.491
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.509 0.491
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.509 0.491
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.509 0.491
E75.6 Lipid storage disorder, unspecified
0.000 0.515 0.485
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.515 0.485
E75.3 Sphingolipidosis, unspecified
0.000 0.515 0.485
E75.2 Other sphingolipidosis
0.000 0.515 0.485
E75.1 Other gangliosidosis
0.000 0.515 0.485
E75.0 GM2 gangliosidosis
0.000 0.515 0.485
E14.6 With other specified complications
0.000 0.521 0.479
E14.1 With ketoacidosis
0.000 0.521 0.479
E11.7 With multiple complications
0.000 0.522 0.478
E14.7 With multiple complications
0.000 0.522 0.478
E14.0 With coma
0.000 0.522 0.478
E11.5 With peripheral circulatory complications
0.000 0.523 0.477
E11.8 With unspecified complications
0.000 0.523 0.477
E14.4 With neurological complications
0.000 0.524 0.476
E14.8 With unspecified complications
0.000 0.530 0.470
E07 Other disorders of thyroid
0.000 0.542 0.458
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.544 0.455
E45 Retarded development following protein-energy malnutrition
0.000 0.544 0.455
E43 Unspecified severe protein-energy malnutrition
0.000 0.544 0.455
E42 Marasmic kwashiorkor
0.000 0.544 0.455
E41 Nutritional marasmus
0.000 0.544 0.455
E40 Kwashiorkor
0.000 0.544 0.455
E11.6 With other specified complications
0.000 0.545 0.454
E13.8 With unspecified complications
0.000 0.547 0.453
E13.7 With multiple complications
0.000 0.547 0.453
E13.6 With other specified complications
0.000 0.547 0.453
E13.5 With peripheral circulatory complications
0.000 0.547 0.453
E13.4 With neurological complications
0.000 0.547 0.453
E13.3 With ophthalmic complications
0.000 0.547 0.453
E13.2 With renal complications
0.000 0.547 0.453
E13.1 With ketoacidosis
0.000 0.547 0.453
E13.0 With coma
0.000 0.547 0.453
E14.2 Withrenal complications
0.000 0.550 0.450
E50-E64 Other nutritional deficiencies
0.000 0.550 0.450
E75.5 Other lipid storage disorders
0.000 0.550 0.449
E88.2 Lipomatosis, not elsewhere classified
0.000 0.560 0.440
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.564 0.436
E11.0 With coma
0.000 0.576 0.424
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.583 0.416
E88.3 Tumour lysis syndrome
0.000 0.588 0.412
E88.9 Metabolic disorder, unspecified
0.000 0.588 0.411
E65 Localised adiposity
0.000 0.598 0.402
E88.8 Other specified metabolic disorders
0.000 0.599 0.400
E11.2 With renal complications
0.000 0.616 0.384
E46 Unspecified protein-energy malnutrition
0.000 0.625 0.374
E67 Other hyperalimentation
0.000 0.629 0.371
E68 Sequelae of hyperalimentation
0.000 0.629 0.371
E13.9 Without complications
0.000 0.632 0.367
E58 Dietary calcium deficiency
0.000 0.662 0.338
E51 Thiamine deficiency
0.000 0.671 0.329
E07.1 Dyshormogenetic goitre
0.000 0.672 0.328
E07.0 Hypersecretion of calcitonin
0.000 0.672 0.328
E44.1 Mild protein-energy malnutrition
0.000 0.673 0.327
E44.0 Moderate protein-energy malnutrition
0.000 0.673 0.327
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.677 0.323
E63 Other nutritional deficiencies
0.000 0.677 0.323
E56 Other vitamin deficiencies
0.000 0.677 0.323
E50 Vitamin A deficiency
0.000 0.677 0.323
E60 Dietary zinc deficiency
0.000 0.677 0.323
E59 Dietary selenium deficiency
0.000 0.677 0.323
E54 Ascorbic acid deficiency
0.000 0.677 0.323
E52 Niacin deficiency [pellagra]
0.000 0.677 0.323
E83.3 Disorders of phosphorus metabolism
0.001 0.696 0.304
K90 Intestinal malabsorption
0.000 0.702 0.298
E03 Other hypothyroidism
0.000 0.718 0.282
E67.8 Other specified hyperalimentation
0.000 0.734 0.266
E67.3 Hypervitaminosis D
0.000 0.734 0.266
E67.2 Megavitamin-B6 syndrome
0.000 0.734 0.266
E67.1 Hypercarotenaemia
0.000 0.734 0.266
E67.0 Hypervitaminosis A
0.000 0.734 0.266
E53 Deficiency of other B group vitamins
0.000 0.738 0.261
E07.8 Other specified disorders of thyroid
0.000 0.739 0.260
E61 Deficiency of other nutrient elements
0.000 0.741 0.258
E04 Other non-toxic goitre
0.000 0.750 0.250
E51.2 Wernicke's encephalopathy
0.000 0.758 0.242
E55 Vitamin D deficiency
0.000 0.761 0.239
E51.9 Thiamine deficiency, unspecified
0.000 0.764 0.236
E51.8 Other manifestations of thiamine deficiency
0.000 0.764 0.236
E51.1 Beriberi
0.000 0.764 0.236
E50.9 Vitamin A deficiency, unspecified
0.000 0.768 0.231
E50.8 Other manifestations of vitamin A deficiency
0.000 0.768 0.231
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.768 0.231
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.768 0.231
E50.5 Vitamin A deficiency with night blindness
0.000 0.768 0.231
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.768 0.231
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.768 0.231
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.768 0.231
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.768 0.231
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.768 0.231
E56.9 Vitamin deficiency, unspecified
0.000 0.768 0.231
E56.8 Deficiency of other vitamins
0.000 0.768 0.231
E56.1 Deficiency of vitamin K
0.000 0.768 0.231
E56.0 Deficiency of vitamin E
0.000 0.768 0.231
E63.9 Nutritional deficiency, unspecified
0.000 0.768 0.231
E63.8 Other specified nutritional deficiencies
0.000 0.768 0.231
E63.1 Imbalance of constituents of food intake
0.000 0.768 0.231
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.768 0.231
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.768 0.231
E64.8 Sequelae of other nutritional deficiencies
0.000 0.768 0.231
E64.3 Sequelae of rickets
0.000 0.768 0.231
E64.2 Sequelae of vitamin C deficiency
0.000 0.768 0.231
E64.1 Sequelae of vitamin A deficiency
0.000 0.768 0.231
E64.0 Sequelae of protein-energy malnutrition
0.000 0.768 0.231
E07.9 Disorder of thyroid, unspecified
0.000 0.776 0.224
E83.4 Disorders of magnesium metabolism
0.000 0.777 0.223
K90.9 Intestinal malabsorption, unspecified
0.000 0.778 0.222
E06 Thyroiditis
0.002 0.782 0.215
E03.8 Other specified hypothyroidism
0.000 0.784 0.216
K90.3 Pancreatic steatorrhoea
0.000 0.786 0.213
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.786 0.213
K90.1 Tropical sprue
0.000 0.786 0.213
L40-L45 Papulosquamous disorders
0.000 0.792 0.208
K90.8 Other intestinal malabsorption
0.000 0.796 0.204
E03.5 Myxoedema coma
0.000 0.797 0.203
E03.4 Atrophy of thyroid (acquired)
0.000 0.797 0.203
E03.3 Postinfectious hypothyroidism
0.000 0.797 0.203
E03.1 Congenital hypothyroidism without goitre
0.000 0.804 0.196
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.812 0.188
E53.1 Pyridoxine deficiency
0.000 0.812 0.188
E53.0 Riboflavin deficiency
0.000 0.812 0.188
E53.9 Vitamin B deficiency, unspecified
0.000 0.813 0.187
E61.9 Deficiency of nutrient element, unspecified
0.000 0.814 0.185
E61.8 Deficiency of other specified nutrient elements
0.000 0.814 0.185
E61.7 Deficiency of multiple nutrient elements
0.000 0.814 0.185
E61.6 Vanadium deficiency
0.000 0.814 0.185
E61.5 Molybdenum deficiency
0.000 0.814 0.185
E61.4 Chromium deficiency
0.000 0.814 0.185
E61.3 Manganese deficiency
0.000 0.814 0.185
E61.2 Magnesium deficiency
0.000 0.814 0.185
E61.0 Copper deficiency
0.000 0.814 0.185
E04.8 Other specified non-toxic goitre
0.000 0.820 0.180
E83.5 Disorders of calcium metabolism
0.000 0.825 0.175
E04.0 Non-toxic diffuse goitre
0.000 0.825 0.175
E55.0 Rickets, active
0.000 0.828 0.171
E20-E35 Disorders of other endocrine glands
0.000 0.833 0.167
E04.1 Non-toxic single thyroid nodule
0.000 0.841 0.159
E06.4 Drug-induced thyroiditis
0.002 0.844 0.155
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.002 0.844 0.155
E06.0 Acute thyroiditis
0.002 0.844 0.155
L44 Other papulosquamous disorders
0.000 0.851 0.149
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.851 0.149
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.854 0.145
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.856 0.144
E06.1 Subacute thyroiditis
0.002 0.858 0.140
E24 Cushing's syndrome
0.000 0.859 0.141
L42 Pityriasis rosea
0.000 0.861 0.139
E06.5 Other chronic thyroiditis
0.002 0.868 0.130
L41 Parapsoriasis
0.000 0.869 0.131
E34 Other endocrine disorders
0.000 0.872 0.128
E53.8 Deficiency of other specified B group vitamins
0.000 0.872 0.128
E28 Ovarian dysfunction
0.000 0.879 0.121
E61.1 Iron deficiency
0.000 0.879 0.121
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.880 0.120
E32 Diseases of thymus
0.000 0.880 0.120
E31 Polyglandular dysfunction
0.000 0.880 0.120
E30 Disorders of puberty, not elsewhere classified
0.000 0.880 0.120
E20 Hypoparathyroidism
0.000 0.882 0.117
E24.9 Cushing's syndrome, unspecified
0.000 0.884 0.116
E27 Other disorders of adrenal gland
0.000 0.889 0.111
E24.0 Pituitary-dependent Cushing's disease
0.000 0.890 0.110
E34.9 Endocrine disorder, unspecified
0.000 0.892 0.108
E25 Adrenogenital disorders
0.000 0.892 0.107
L44.9 Papulosquamous disorder, unspecified
0.000 0.893 0.107
L44.8 Other specified papulosquamous disorders
0.000 0.893 0.107
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.893 0.107
L44.3 Lichen ruber moniliformis
0.000 0.893 0.107
L44.2 Lichen striatus
0.000 0.893 0.107
L44.1 Lichen nitidus
0.000 0.893 0.107
L44.0 Pityriasis rubra pilaris
0.000 0.893 0.107
E22 Hyperfunction of pituitary gland
0.000 0.894 0.106
E24.2 Drug-induced Cushing's syndrome
0.000 0.895 0.105
E06.9 Thyroiditis, unspecified
0.002 0.896 0.102
E28.3 Primary ovarian failure
0.000 0.896 0.104
E04.9 Non-toxic goitre, unspecified
0.000 0.896 0.104
L43 Lichen planus
0.000 0.897 0.103
E24.8 Other Cushing's syndrome
0.000 0.898 0.101
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.898 0.101
E24.3 Ectopic ACTH syndrome
0.000 0.898 0.101
E24.1 Nelson's syndrome
0.000 0.898 0.101
E29 Testicular dysfunction
0.000 0.901 0.098
E27.1 Primary adrenocortical insufficiency
0.000 0.903 0.097
L41.9 Parapsoriasis, unspecified
0.000 0.906 0.094
L41.8 Other parapsoriasis
0.000 0.906 0.094
L41.5 Retiform parapsoriasis
0.000 0.906 0.094
L41.4 Large plaque parapsoriasis
0.000 0.906 0.094
L41.3 Small plaque parapsoriasis
0.000 0.906 0.094
L41.2 Lymphomatoid papulosis
0.000 0.906 0.094
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.906 0.094
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.907 0.093
E34.5 Androgen resistance syndrome
0.000 0.908 0.092
E34.4 Constitutional tall stature
0.000 0.908 0.092
E34.3 Short stature, not elsewhere classified
0.000 0.908 0.092
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.908 0.092
E34.1 Other hypersecretion of intestinal hormones
0.000 0.908 0.092
E26 Hyperaldosteronism
0.000 0.911 0.089
E34.0 Carcinoid syndrome
0.000 0.911 0.089
E55.9 Vitamin D deficiency, unspecified
0.000 0.912 0.088
E28.9 Ovarian dysfunction, unspecified
0.000 0.913 0.087
E28.8 Other ovarian dysfunction
0.000 0.913 0.087
E28.1 Androgen excess
0.000 0.913 0.087
E28.0 Oestrogen excess
0.000 0.913 0.087
E30.9 Disorder of puberty, unspecified
0.000 0.914 0.086
E30.8 Other disorders of puberty
0.000 0.914 0.086
E30.1 Precocious puberty
0.000 0.914 0.086
E30.0 Delayed puberty
0.000 0.914 0.086
E31.9 Polyglandular dysfunction, unspecified
0.000 0.914 0.086
E31.8 Other polyglandular dysfunction
0.000 0.914 0.086
E31.1 Polyglandular hyperfunction
0.000 0.914 0.086
E31.0 Autoimmune polyglandular failure
0.000 0.914 0.086
E32.9 Disease of thymus, unspecified
0.000 0.914 0.086
E32.8 Other diseases of thymus
0.000 0.914 0.086
E32.1 Abscess of thymus
0.000 0.914 0.086
E32.0 Persistent hyperplasia of thymus
0.000 0.914 0.086
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.914 0.086
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.914 0.086
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.914 0.086
E27.2 Addisonian crisis
0.000 0.914 0.086
E20.8 Other hypoparathyroidism
0.000 0.915 0.084
E20.1 Pseudohypoparathyroidism
0.000 0.915 0.084
E20.0 Idiopathic hypoparathyroidism
0.000 0.915 0.084
E20.9 Hypoparathyroidism, unspecified
0.000 0.918 0.082
E34.8 Other specified endocrine disorders
0.000 0.918 0.082
E27.8 Other specified disorders of adrenal gland
0.000 0.920 0.080
E27.5 Adrenomedullary hyperfunction
0.000 0.920 0.080
E27.0 Other adrenocortical overactivity
0.000 0.920 0.080
E25.9 Adrenogenital disorder, unspecified
0.000 0.923 0.077
E25.8 Other adrenogenital disorders
0.000 0.923 0.077
E66 Obesity
0.000 0.923 0.077
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.923 0.076
E22.8 Other hyperfunction of pituitary gland
0.000 0.923 0.076
L41.1 Pityriasis lichenoides chronica
0.001 0.924 0.075
L43.3 Subacute (active) lichen planus
0.000 0.926 0.074
L43.2 Lichenoid drug reaction
0.000 0.926 0.074
L43.1 Bullous lichen planus
0.000 0.926 0.074
L43.0 Hypertrophic lichen planus
0.000 0.926 0.074
E04.2 Non-toxic multinodular goitre
0.000 0.926 0.074
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.928 0.072
E29.9 Testicular dysfunction, unspecified
0.000 0.929 0.071
E29.8 Other testicular dysfunction
0.000 0.929 0.071
E29.0 Testicular hyperfunction
0.000 0.929 0.071
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.930 0.070
E22.1 Hyperprolactinaemia
0.000 0.932 0.068
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.935 0.065
E26.8 Other hyperaldosteronism
0.000 0.936 0.064
E26.1 Secondary hyperaldosteronism
0.000 0.936 0.064
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.942 0.058
E28.2 Polycystic ovarian syndrome
0.000 0.942 0.058
L43.9 Lichen planus, unspecified
0.000 0.944 0.056
L43.8 Other lichen planus
0.000 0.944 0.056
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.944 0.056
E26.9 Hyperaldosteronism, unspecified
0.000 0.944 0.055
E66.1 Drug-induced obesity
0.000 0.945 0.055
E06.3 Autoimmune thyroiditis
0.003 0.946 0.052
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.947 0.053
E29.1 Testicular hypofunction
0.000 0.950 0.049
E23 Hypofunction and other disorders of pituitary gland
0.000 0.951 0.049
E78.8 Other disorders of lipoprotein metabolism
0.000 0.952 0.048
E26.0 Primary hyperaldosteronism
0.000 0.952 0.047
E66.0 Obesity due to excess calories
0.000 0.952 0.047
E78.6 Lipoprotein deficiency
0.000 0.955 0.045
E27.9 Disorder of adrenal gland, unspecified
0.001 0.956 0.043
E14.9 Without complications
0.000 0.958 0.042
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.961 0.039
E78.1 Pure hyperglyceridaemia
0.000 0.961 0.039
E21.4 Other specified disorders of parathyroid gland
0.000 0.962 0.038
E78.4 Other hyperlipidaemia
0.000 0.962 0.038
E78.3 Hyperchylomicronaemia
0.000 0.963 0.037
E21.3 Hyperparathyroidism, unspecified
0.000 0.965 0.035
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.965 0.035
E23.1 Drug-induced hypopituitarism
0.000 0.965 0.035
E21.2 Other hyperparathyroidism
0.000 0.965 0.035
E23.2 Diabetes insipidus
0.000 0.967 0.033
E23.7 Disorder of pituitary gland, unspecified
0.000 0.968 0.032
E22.0 Acromegaly and pituitary gigantism
0.001 0.970 0.029
E78.2 Mixed hyperlipidaemia
0.000 0.970 0.029
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.973 0.026
E23.6 Other disorders of pituitary gland
0.000 0.975 0.025
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.976 0.024
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.977 0.023
R60.9 Oedema, unspecified
0.000 0.978 0.022
E86 Volume depletion
0.000 0.979 0.021
N40-N51 Diseases of male genital organs
0.021 0.979 0.000
E87.3 Alkalosis
0.000 0.980 0.020
E21.0 Primary hyperparathyroidism
0.000 0.980 0.020
K90-K93 Other diseases of the digestive system
0.000 0.980 0.020
N41 Inflammatory diseases of prostate
0.019 0.981 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.019 0.981 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.982 0.018
E87.4 Mixed disorder of acid-base balance
0.000 0.983 0.017
N46 Male infertility
0.015 0.985 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.015 0.985 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.015 0.985 0.000
N42 Other disorders of prostate
0.015 0.985 0.000
E23.0 Hypopituitarism
0.000 0.985 0.015
N42.1 Congestion and haemorrhage of prostate
0.015 0.985 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.985 0.014
N44 Torsion of testis
0.014 0.986 0.000
N41.8 Other inflammatory diseases of prostate
0.014 0.986 0.000
N41.3 Prostatocystitis
0.014 0.986 0.000
N41.2 Abscess of prostate
0.014 0.986 0.000
N41.1 Chronic prostatitis
0.014 0.986 0.000
N41.0 Acute prostatitis
0.014 0.986 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.987 0.013
E87.0 Hyperosmolality and hypernatraemia
0.000 0.988 0.012
N45 Orchitis and epididymitis
0.012 0.988 0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.012 0.988 0.000
E87.7 Fluid overload
0.000 0.989 0.011
N49.2 Inflammatory disorders of scrotum
0.011 0.989 0.000
N42.0 Calculus of prostate
0.011 0.989 0.000
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.011 0.989 0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.011 0.989 0.000
N51.0 Disorders of prostate in diseases classified elsewhere
0.011 0.989 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.011 0.989 0.000
N49.0 Inflammatory disorders of seminal vesicle
0.011 0.989 0.000
N51.2 Balanitis in diseases classified elsewhere
0.011 0.989 0.000
N42.3 Dysplasia of prostate
0.011 0.989 0.000
C81.9 Hodgkin's disease, unspecified
0.011 0.989 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.989 0.010
K93.1 Megacolon in Chagas' disease
0.000 0.989 0.010
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.989 0.010
N49.8 Inflammatory disorders of other specified male genital organs
0.010 0.990 0.000
I46.0 Cardiac arrest with successful resuscitation
0.000 0.990 0.010
I71.0 Dissection of aorta [any part]
0.010 0.990 0.000
E87.5 Hyperkalaemia
0.000 0.991 0.009
I71 Aortic aneurysm and dissection
0.009 0.991 0.000
N42.2 Atrophy of prostate
0.009 0.991 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.009 0.991 0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.009 0.991 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.991 0.008
N42.8 Other specified disorders of prostate
0.009 0.991 0.000
E66.8 Other obesity
0.000 0.991 0.009

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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