TreeWAS – Variant ID: rs2523388

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
G35 Multiple sclerosis	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.058	0.942
M06.9 Rheumatoid arthritis, unspecified	0.918	0.082	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.913	0.087	0.000
M06 Other rheumatoid arthritis	0.889	0.111	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.885	0.115	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.124	0.876
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.840	0.160	0.000
M06.0 Seronegative rheumatoid arthritis	0.828	0.172	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.802	0.198	0.000
G40-G47 Episodic and paroxysmal disorders	0.000	0.202	0.798
G40 Epilepsy	0.000	0.205	0.795
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.206	0.794
Chapter VI Diseases of the nervous system	0.000	0.208	0.792
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.767	0.233	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.238	0.762
M06.8 Other specified rheumatoid arthritis	0.760	0.240	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.250	0.750
G30-G32 Other degenerative diseases of the nervous system	0.000	0.253	0.747
M06.3 Rheumatoid nodule	0.739	0.261	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.263	0.737
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.264	0.736
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.272	0.728
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.283	0.717
G43 Migraine	0.000	0.283	0.717
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.715	0.285	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.285	0.715
M05-M14 Inflammatory polyarthropathies	0.714	0.286	0.000
M05 Seropositive rheumatoid arthritis	0.711	0.289	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.708	0.292	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.293	0.707
G43.9 Migraine, unspecified	0.000	0.298	0.702
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.700	0.300	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.305	0.695
G47 Sleep disorders	0.000	0.312	0.688
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.685	0.315	0.000
G47.9 Sleep disorder, unspecified	0.000	0.325	0.675
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.668	0.332	0.000
M06.34 Rheumatoid nodule (Hand)	0.667	0.333	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.666	0.334	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.663	0.337	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.341	0.659
E00-E07 Disorders of thyroid gland	0.000	0.344	0.656
E06 Thyroiditis	0.000	0.346	0.654
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.651	0.349	0.000
G44 Other headache syndromes	0.000	0.354	0.646
G36 Other acute disseminated demyelination	0.000	0.356	0.644
E06.3 Autoimmune thyroiditis	0.000	0.358	0.642
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.638	0.362	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.638	0.362	0.000
M06.2 Rheumatoid bursitis	0.637	0.362	0.000
M06.1 Adult-onset Still's disease	0.637	0.362	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.363	0.637
G31.8 Other specified degenerative diseases of nervous system	0.000	0.370	0.630
G37.5 Concentric sclerosis [Balo]	0.000	0.372	0.628
G37.4 Subacute necrotising myelitis	0.000	0.372	0.628
G37.2 Central pontine myelinolysis	0.000	0.372	0.628
G37.1 Central demyelination of corpus callosum	0.000	0.372	0.628
G37.0 Diffuse sclerosis	0.000	0.372	0.628
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.626	0.374	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.375	0.625
G40.9 Epilepsy, unspecified	0.000	0.376	0.624
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.623	0.377	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.379	0.621
M06.04 Seronegative rheumatoid arthritis (Hand)	0.617	0.383	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.389	0.611
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.610	0.390	0.000
E06.9 Thyroiditis, unspecified	0.000	0.391	0.609
M12 Other specific arthropathies	0.597	0.403	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.000	0.405	0.595
M06.08 Seronegative rheumatoid arthritis (Other)	0.593	0.406	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.593	0.406	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.593	0.406	0.000
G44.2 Tension-type headache	0.000	0.410	0.590
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.587	0.413	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.419	0.581
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.576	0.424	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.430	0.570
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.431	0.569
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.567	0.432	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.564	0.436	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.438	0.562
M05.8 Other seropositive rheumatoid arthritis	0.562	0.438	0.000
G47.2 Disorders of the sleep-wake schedule	0.000	0.439	0.561
G47.1 Disorders of excessive somnolence [hypersomnias]	0.000	0.446	0.554
G81 Hemiplegia	0.000	0.450	0.550
M06.33 Rheumatoid nodule (Forearm)	0.547	0.453	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.545	0.455	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.545	0.455	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.545	0.455	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.545	0.455	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.545	0.455	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.545	0.455	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.545	0.455	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.545	0.455	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.544	0.456	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.542	0.458	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.469	0.531
G41 Status epilepticus	0.000	0.470	0.530
M06.39 Rheumatoid nodule (Site unspecified)	0.530	0.470	0.000
M06.38 Rheumatoid nodule (Other)	0.530	0.470	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.530	0.470	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.530	0.470	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.530	0.470	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.527	0.472	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.523	0.476	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.478	0.522
E03 Other hypothyroidism	0.000	0.483	0.517
G44.3 Chronic posttraumatic headache	0.000	0.483	0.517
E05.5 Thyroid crisis or storm	0.000	0.486	0.514
E05.4 Thyrotoxicosis factitia	0.000	0.486	0.514
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.486	0.514
G43.2 Status migrainosus	0.000	0.486	0.514
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.513	0.487	0.000
E06.5 Other chronic thyroiditis	0.000	0.487	0.513
M09 Juvenile arthritis in diseases classified elsewhere	0.512	0.488	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.490	0.510
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.510	0.490	0.000
M05.0 Felty's syndrome	0.510	0.490	0.000
G81.9 Hemiplegia, unspecified	0.000	0.490	0.510
M05.1 Rheumatoid lung disease	0.509	0.491	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.508	0.492	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.508	0.492	0.000
G43.0 Migraine without aura [common migraine]	0.000	0.493	0.507
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.498	0.502
G31.0 Circumscribed brain atrophy	0.000	0.498	0.502
G06 Intracranial and intraspinal abscess and granuloma	0.000	0.500	0.500
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.503	0.497
G40.5 Special epileptic syndromes	0.000	0.503	0.497
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.000	0.507	0.493
M06.4 Inflammatory polyarthropathy	0.489	0.511	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.511	0.489
M08 Juvenile arthritis	0.484	0.515	0.000
M05.2 Rheumatoid vasculitis	0.482	0.518	0.000
E05.8 Other thyrotoxicosis	0.000	0.518	0.482
M11 Other crystal arthropathies	0.478	0.522	0.000
M12.2 Villonodular synovitis (pigmented)	0.474	0.526	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.000	0.528	0.472
M12.3 Palindromic rheumatism	0.471	0.529	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.529	0.470
E00 Congenital iodine-deficiency syndrome	0.000	0.529	0.470
E06.4 Drug-induced thyroiditis	0.000	0.531	0.469
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.531	0.469
E06.0 Acute thyroiditis	0.000	0.531	0.469
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.467	0.533	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.538	0.462
G36.9 Acute disseminated demyelination, unspecified	0.000	0.538	0.461
G36.8 Other specified acute disseminated demyelination	0.000	0.538	0.461
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.538	0.461
G46.7 Other lacunar syndromes	0.000	0.539	0.461
M06.19 Adult-onset Still's disease (Site unspecified)	0.457	0.543	0.000
M06.18 Adult-onset Still's disease (Other)	0.457	0.543	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.457	0.543	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.457	0.543	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.457	0.543	0.000
M06.14 Adult-onset Still's disease (Hand)	0.457	0.543	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.457	0.543	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.457	0.543	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.457	0.543	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.457	0.543	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.457	0.543	0.000
M06.28 Rheumatoid bursitis (Other)	0.457	0.543	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.457	0.543	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.457	0.543	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.457	0.543	0.000
M06.24 Rheumatoid bursitis (Hand)	0.457	0.543	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.457	0.543	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.457	0.543	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.457	0.543	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.457	0.543	0.000
G44.8 Other specified headache syndromes	0.000	0.545	0.455
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.455	0.545	0.000
G82 Paraplegia and tetraplegia	0.000	0.546	0.454
M06.30 Rheumatoid nodule (Multiple sites)	0.452	0.547	0.000
M14 Arthropathies in other diseases classified elsewhere	0.451	0.548	0.000
E07 Other disorders of thyroid	0.000	0.549	0.451
G03 Meningitis due to other and unspecified causes	0.000	0.551	0.448
G43.1 Migraine with aura [classical migraine]	0.000	0.557	0.443
G00 Bacterial meningitis, not elsewhere classified	0.000	0.557	0.443
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.557	0.443
M12.5 Traumatic arthropathy	0.442	0.558	0.000
G47.4 Narcolepsy and cataplexy	0.000	0.559	0.441
M06.32 Rheumatoid nodule (Upper arm)	0.441	0.559	0.000
E83 Disorders of mineral metabolism	0.000	0.564	0.436
G46.4 Cerebellar stroke syndrome	0.000	0.565	0.435
G36.0 Neuromyelitis optica [Devic]	0.000	0.570	0.430
M12.8 Other specific arthropathies, not elsewhere classified	0.428	0.572	0.000
M12.4 Intermittent hydrarthrosis	0.428	0.572	0.000
M12.1 Kaschin-Beck disease	0.428	0.572	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.428	0.572	0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.000	0.573	0.426
G46.6 Pure sensory lacunar syndrome	0.000	0.573	0.426
G46.5 Pure motor lacunar syndrome	0.000	0.573	0.426
G46.2 Posterior cerebral artery syndrome	0.000	0.573	0.426
G46.1 Anterior cerebral artery syndrome	0.000	0.573	0.426
G46.0 Middle cerebral artery syndrome	0.000	0.573	0.426
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.578	0.422
G43.3 Complicated migraine	0.000	0.579	0.421
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.581	0.419
E03.9 Hypothyroidism, unspecified	0.000	0.582	0.418
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.583	0.417
G44.0 Cluster headache syndrome	0.000	0.587	0.413
M35.0 Sicca syndrome [Sjogren]	0.000	0.590	0.410
G06.1 Intraspinal abscess and granuloma	0.000	0.590	0.410
M13 Other arthritis	0.410	0.590	0.000
G06.2 Extradural and subdural abscess, unspecified	0.000	0.594	0.406
G40.8 Other epilepsy	0.000	0.594	0.406
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.000	0.595	0.405
G70-G73 Diseases of myoneural junction and muscle	0.000	0.596	0.404
G45.3 Amaurosis fugax	0.000	0.597	0.403
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.403	0.597	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.403	0.597	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.403	0.597	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.403	0.597	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.403	0.597	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.403	0.597	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.403	0.597	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.403	0.597	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.403	0.597	0.000
G46.3 Brain stem stroke syndrome	0.000	0.598	0.402
G81.0 Flaccid hemiplegia	0.000	0.605	0.394
G44.1 Vascular headache, not elsewhere classified	0.000	0.607	0.393
E06.1 Subacute thyroiditis	0.000	0.609	0.391
G41.0 Grand mal status epilepticus	0.000	0.609	0.391
M12.24 Villonodular synovitis (pigmented) (Hand)	0.385	0.615	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.617	0.383
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.617	0.383
G81.1 Spastic hemiplegia	0.000	0.617	0.383
G41.8 Other status epilepticus	0.000	0.620	0.380
G41.2 Complex partial status epilepticus	0.000	0.620	0.380
G41.1 Petit mal status epilepticus	0.000	0.620	0.380
G80 Infantile cerebral palsy	0.000	0.620	0.380
E83.5 Disorders of calcium metabolism	0.000	0.624	0.376
G82.1 Spastic paraplegia	0.000	0.625	0.375
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.626	0.374
G44.4 Drug-induced headache, not elsewhere classified	0.000	0.626	0.373
E03.5 Myxoedema coma	0.000	0.629	0.371
E03.4 Atrophy of thyroid (acquired)	0.000	0.629	0.371
E03.3 Postinfectious hypothyroidism	0.000	0.629	0.371
M13.8 Other specified arthritis	0.370	0.630	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.367	0.632	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.367	0.632	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.367	0.632	0.000
M09.0 Juvenile arthritis in psoriasis	0.367	0.632	0.000
E07.8 Other specified disorders of thyroid	0.000	0.633	0.367
M12.39 Palindromic rheumatism (Site unspecified)	0.366	0.634	0.000
M05.09 Felty's syndrome (Site unspecified)	0.365	0.634	0.000
M05.08 Felty's syndrome (Other)	0.365	0.634	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.365	0.634	0.000
M05.06 Felty's syndrome (Lower leg)	0.365	0.634	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.365	0.634	0.000
M05.04 Felty's syndrome (Hand)	0.365	0.634	0.000
M05.03 Felty's syndrome (Forearm)	0.365	0.634	0.000
M05.02 Felty's syndrome (Upper arm)	0.365	0.634	0.000
M05.01 Felty's syndrome (Shoulder region)	0.365	0.634	0.000
M05.00 Felty's syndrome (Multiple sites)	0.365	0.634	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.365	0.634	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.365	0.634	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.365	0.634	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.365	0.634	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.365	0.634	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.365	0.634	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.365	0.634	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.365	0.634	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.365	0.634	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.365	0.634	0.000
M05.18 Rheumatoid lung disease (Other)	0.365	0.635	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.365	0.635	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.365	0.635	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.365	0.635	0.000
M05.14 Rheumatoid lung disease (Hand)	0.365	0.635	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.365	0.635	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.365	0.635	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.365	0.635	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.365	0.635	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.365	0.635	0.000
G47.8 Other sleep disorders	0.000	0.638	0.362
M11.9 Crystal arthropathy, unspecified	0.359	0.641	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.643	0.356
G04.1 Tropical spastic paraplegia	0.000	0.643	0.356
G04.0 Acute disseminated encephalitis	0.000	0.643	0.356
M12.30 Palindromic rheumatism (Multiple sites)	0.356	0.644	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.645	0.355
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.000	0.647	0.353
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.000	0.647	0.353
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.000	0.647	0.353
G90-G99 Other disorders of the nervous system	0.000	0.647	0.353
M14.8 Arthropathies in other specified diseases classified elsewhere	0.351	0.648	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.649	0.351
M06.48 Inflammatory polyarthropathy (Other)	0.351	0.649	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.351	0.649	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.351	0.649	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.351	0.649	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.351	0.649	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.351	0.649	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.351	0.649	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.351	0.649	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.652	0.348
M11.8 Other specified crystal arthropathies	0.348	0.652	0.000
M08.9 Juvenile arthritis, unspecified	0.347	0.652	0.000
M08.8 Other juvenile arthritis	0.347	0.652	0.000
M08.4 Pauciarticular juvenile arthritis	0.347	0.652	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.347	0.652	0.000
M08.2 Juvenile arthritis with systemic onset	0.347	0.652	0.000
M08.1 Juvenile ankylosing spondylitis	0.347	0.652	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.347	0.653	0.000
G82.4 Spastic tetraplegia	0.000	0.653	0.347
M05.28 Rheumatoid vasculitis (Other)	0.345	0.654	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.345	0.654	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.345	0.654	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.345	0.654	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.345	0.654	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.345	0.654	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.345	0.654	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.345	0.654	0.000
G43.8 Other migraine	0.000	0.655	0.344
M11.1 Familial chondrocalcinosis	0.343	0.657	0.000
M11.0 Hydroxyapatite deposition disease	0.343	0.657	0.000
M12.26 Villonodular synovitis (pigmented) (Lower leg)	0.341	0.659	0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.340	0.660	0.000
M12.28 Villonodular synovitis (pigmented) (Other)	0.340	0.660	0.000
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.340	0.660	0.000
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.340	0.660	0.000
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.340	0.660	0.000
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.340	0.660	0.000
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.340	0.660	0.000
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.340	0.660	0.000
G82.5 Tetraplegia, unspecified	0.000	0.661	0.338
M12.38 Palindromic rheumatism (Other)	0.338	0.662	0.000
M12.37 Palindromic rheumatism (Ankle and foot)	0.338	0.662	0.000
M12.36 Palindromic rheumatism (Lower leg)	0.338	0.662	0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.338	0.662	0.000
M12.34 Palindromic rheumatism (Hand)	0.338	0.662	0.000
M12.33 Palindromic rheumatism (Forearm)	0.338	0.662	0.000
M12.32 Palindromic rheumatism (Upper arm)	0.338	0.662	0.000
M12.31 Palindromic rheumatism (Shoulder region)	0.338	0.662	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.662	0.337
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.662	0.337
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.662	0.337
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.662	0.337
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.662	0.337
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.662	0.337
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.662	0.337
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.662	0.337
E03.1 Congenital hypothyroidism without goitre	0.000	0.667	0.333
M12.57 Traumatic arthropathy (Ankle and foot)	0.330	0.670	0.000
G00.1 Pneumococcal meningitis	0.000	0.670	0.330
E03.8 Other specified hypothyroidism	0.000	0.671	0.329
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.327	0.673	0.000
G82.3 Flaccid tetraplegia	0.000	0.674	0.326
G82.0 Flaccid paraplegia	0.000	0.674	0.326
G41.9 Status epilepticus, unspecified	0.000	0.675	0.324
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.324	0.676	0.000
M14.4 Arthropathy in amyloidosis	0.324	0.676	0.000
M14.3 Lipoid dermatoarthritis	0.324	0.676	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.324	0.676	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.324	0.676	0.000
E07.1 Dyshormogenetic goitre	0.000	0.677	0.323
E07.0 Hypersecretion of calcitonin	0.000	0.677	0.323
G03.8 Meningitis due to other specified causes	0.000	0.678	0.322
G03.2 Benign recurrent meningitis [Mollaret]	0.000	0.678	0.322
G03.1 Chronic meningitis	0.000	0.678	0.322
G03.0 Nonpyogenic meningitis	0.000	0.678	0.322
M08.0 Juvenile rheumatoid arthritis	0.319	0.680	0.000
G00.8 Other bacterial meningitis	0.000	0.682	0.317
G00.3 Staphylococcal meningitis	0.000	0.682	0.317
G00.2 Streptococcal meningitis	0.000	0.682	0.317
G00.0 Haemophilus meningitis	0.000	0.682	0.317
M12.59 Traumatic arthropathy (Site unspecified)	0.317	0.683	0.000
M12.58 Traumatic arthropathy (Other)	0.317	0.683	0.000
M12.56 Traumatic arthropathy (Lower leg)	0.317	0.683	0.000
M12.55 Traumatic arthropathy (Pelvic region and thigh)	0.317	0.683	0.000
M12.54 Traumatic arthropathy (Hand)	0.317	0.683	0.000
M12.53 Traumatic arthropathy (Forearm)	0.317	0.683	0.000
M12.52 Traumatic arthropathy (Upper arm)	0.317	0.683	0.000
M12.51 Traumatic arthropathy (Shoulder region)	0.317	0.683	0.000
M12.50 Traumatic arthropathy (Multiple sites)	0.317	0.683	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.316	0.683	0.000
M07 Psoriatic and enteropathic arthropathies	0.316	0.684	0.001
G70 Myasthenia gravis and other myoneural disorders	0.000	0.685	0.315
G99 Other disorders of nervous system in diseases classified elsewhere	0.000	0.685	0.315
M13.89 Other specified arthritis (Site unspecified)	0.314	0.686	0.000
E83.8 Other disorders of mineral metabolism	0.000	0.687	0.312
E83.2 Disorders of zinc metabolism	0.000	0.687	0.312
E83.0 Disorders of copper metabolism	0.000	0.687	0.312
G83 Other paralytic syndromes	0.000	0.690	0.310
G80.8 Other infantile cerebral palsy	0.000	0.691	0.308
M12.09 Chronic postrheumatic arthropathy [Jaccoud] (Site unspecified)	0.307	0.693	0.000
M12.08 Chronic postrheumatic arthropathy [Jaccoud] (Other)	0.307	0.693	0.000
M12.07 Chronic postrheumatic arthropathy [Jaccoud] (Ankle and foot)	0.307	0.693	0.000
M12.06 Chronic postrheumatic arthropathy [Jaccoud] (Lower leg)	0.307	0.693	0.000
M12.05 Chronic postrheumatic arthropathy [Jaccoud] (Pelvic region and thigh)	0.307	0.693	0.000
M12.04 Chronic postrheumatic arthropathy [Jaccoud] (Hand)	0.307	0.693	0.000
M12.03 Chronic postrheumatic arthropathy [Jaccoud] (Forearm)	0.307	0.693	0.000
M12.02 Chronic postrheumatic arthropathy [Jaccoud] (Upper arm)	0.307	0.693	0.000
M12.01 Chronic postrheumatic arthropathy [Jaccoud] (Shoulder region)	0.307	0.693	0.000
M12.00 Chronic postrheumatic arthropathy [Jaccoud] (Multiple sites)	0.307	0.693	0.000
M12.19 Kaschin-Beck disease (Site unspecified)	0.307	0.693	0.000
M12.18 Kaschin-Beck disease (Other)	0.307	0.693	0.000
M12.17 Kaschin-Beck disease (Ankle and foot)	0.307	0.693	0.000
M12.16 Kaschin-Beck disease (Lower leg)	0.307	0.693	0.000
M12.15 Kaschin-Beck disease (Pelvic region and thigh)	0.307	0.693	0.000
M12.14 Kaschin-Beck disease (Hand)	0.307	0.693	0.000
M12.13 Kaschin-Beck disease (Forearm)	0.307	0.693	0.000
M12.12 Kaschin-Beck disease (Upper arm)	0.307	0.693	0.000
M12.11 Kaschin-Beck disease (Shoulder region)	0.307	0.693	0.000
M12.10 Kaschin-Beck disease (Multiple sites)	0.307	0.693	0.000
M12.49 Intermittent hydrarthrosis (Site unspecified)	0.307	0.693	0.000
M12.48 Intermittent hydrarthrosis (Other)	0.307	0.693	0.000
M12.47 Intermittent hydrarthrosis (Ankle and foot)	0.307	0.693	0.000
M12.46 Intermittent hydrarthrosis (Lower leg)	0.307	0.693	0.000
M12.45 Intermittent hydrarthrosis (Pelvic region and thigh)	0.307	0.693	0.000
M12.44 Intermittent hydrarthrosis (Hand)	0.307	0.693	0.000
M12.43 Intermittent hydrarthrosis (Forearm)	0.307	0.693	0.000
M12.42 Intermittent hydrarthrosis (Upper arm)	0.307	0.693	0.000
M12.41 Intermittent hydrarthrosis (Shoulder region)	0.307	0.693	0.000
M12.40 Intermittent hydrarthrosis (Multiple sites)	0.307	0.693	0.000
M12.89 Other specific arthropathies, not elsewhere classified (Site unspecified)	0.307	0.693	0.000
M12.88 Other specific arthropathies, not elsewhere classified (Other)	0.307	0.693	0.000
M12.87 Other specific arthropathies, not elsewhere classified (Ankle and foot)	0.307	0.693	0.000
M12.86 Other specific arthropathies, not elsewhere classified (Lower leg)	0.307	0.693	0.000
M12.85 Other specific arthropathies, not elsewhere classified (Pelvic region and thigh)	0.307	0.693	0.000
M12.84 Other specific arthropathies, not elsewhere classified (Hand)	0.307	0.693	0.000
M12.83 Other specific arthropathies, not elsewhere classified (Forearm)	0.307	0.693	0.000
M12.82 Other specific arthropathies, not elsewhere classified (Upper arm)	0.307	0.693	0.000
M12.81 Other specific arthropathies, not elsewhere classified (Shoulder region)	0.307	0.693	0.000
M12.80 Other specific arthropathies, not elsewhere classified (Multiple sites)	0.307	0.693	0.000
G30 Alzheimer's disease	0.000	0.694	0.306
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.696	0.304
G45.2 Multiple and bilateral precerebral artery syndromes	0.000	0.697	0.303
G45.1 Carotid artery syndrome (hemispheric)	0.000	0.700	0.300
G03.9 Meningitis, unspecified	0.000	0.702	0.298
M13.80 Other specified arthritis (Multiple sites)	0.298	0.702	0.000
M10 Gout	0.296	0.704	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.708	0.292
G80.9 Infantile cerebral palsy, unspecified	0.000	0.709	0.291
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.000	0.709	0.291
G02.1 Meningitis in mycoses	0.000	0.709	0.291
M13.86 Other specified arthritis (Lower leg)	0.290	0.709	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.000	0.710	0.290
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.710	0.289
M14.2 Diabetic arthropathy	0.289	0.711	0.000
G96 Other disorders of central nervous system	0.000	0.720	0.280
M11.2 Other chondrocalcinosis	0.277	0.723	0.000
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.274	0.725	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.726	0.274
G80.4 Ataxic cerebral palsy	0.000	0.727	0.273
G80.3 Dyskinetic cerebral palsy	0.000	0.727	0.273
G00.9 Bacterial meningitis, unspecified	0.000	0.729	0.271
M13.1 Monoarthritis, not elsewhere classified	0.271	0.729	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.000	0.734	0.266
M13.88 Other specified arthritis (Other)	0.265	0.735	0.000
M13.87 Other specified arthritis (Ankle and foot)	0.265	0.735	0.000
M13.85 Other specified arthritis (Pelvic region and thigh)	0.265	0.735	0.000
M13.84 Other specified arthritis (Hand)	0.265	0.735	0.000
M13.83 Other specified arthritis (Forearm)	0.265	0.735	0.000
M13.82 Other specified arthritis (Upper arm)	0.265	0.735	0.000
M13.81 Other specified arthritis (Shoulder region)	0.265	0.735	0.000
M13.0 Polyarthritis, unspecified	0.264	0.736	0.000
M09.09 Juvenile arthritis in psoriasis (Site unspecified)	0.263	0.736	0.000
M09.08 Juvenile arthritis in psoriasis (Other)	0.263	0.736	0.000
M09.07 Juvenile arthritis in psoriasis (Ankle and foot)	0.263	0.736	0.000
M09.06 Juvenile arthritis in psoriasis (Lower leg)	0.263	0.736	0.000
M09.05 Juvenile arthritis in psoriasis (Pelvic region and thigh)	0.263	0.736	0.000
M09.04 Juvenile arthritis in psoriasis (Hand)	0.263	0.736	0.000
M09.03 Juvenile arthritis in psoriasis (Forearm)	0.263	0.736	0.000
M09.02 Juvenile arthritis in psoriasis (Upper arm)	0.263	0.736	0.000
M09.01 Juvenile arthritis in psoriasis (Shoulder region)	0.263	0.736	0.000
M09.00 Juvenile arthritis in psoriasis (Multiple sites)	0.263	0.736	0.000
M09.19 Juvenile arthritis in Crohn's disease [regional enteritis] (Site unspecified)	0.263	0.736	0.000
M09.18 Juvenile arthritis in Crohn's disease [regional enteritis] (Other)	0.263	0.736	0.000
M09.17 Juvenile arthritis in Crohn's disease [regional enteritis] (Ankle and foot)	0.263	0.736	0.000
M09.16 Juvenile arthritis in Crohn's disease [regional enteritis] (Lower leg)	0.263	0.736	0.000
M09.15 Juvenile arthritis in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.263	0.736	0.000
M09.14 Juvenile arthritis in Crohn's disease [regional enteritis] (Hand)	0.263	0.736	0.000
M09.13 Juvenile arthritis in Crohn's disease [regional enteritis] (Forearm)	0.263	0.736	0.000
M09.12 Juvenile arthritis in Crohn's disease [regional enteritis] (Upper arm)	0.263	0.736	0.000
M09.11 Juvenile arthritis in Crohn's disease [regional enteritis] (Shoulder region)	0.263	0.736	0.000
M09.10 Juvenile arthritis in Crohn's disease [regional enteritis] (Multiple sites)	0.263	0.736	0.000
M09.29 Juvenile arthritis in ulcerative colitis (Site unspecified)	0.263	0.736	0.000
M09.28 Juvenile arthritis in ulcerative colitis (Other)	0.263	0.736	0.000
M09.27 Juvenile arthritis in ulcerative colitis (Ankle and foot)	0.263	0.736	0.000
M09.26 Juvenile arthritis in ulcerative colitis (Lower leg)	0.263	0.736	0.000
M09.25 Juvenile arthritis in ulcerative colitis (Pelvic region and thigh)	0.263	0.736	0.000
M09.24 Juvenile arthritis in ulcerative colitis (Hand)	0.263	0.736	0.000
M09.23 Juvenile arthritis in ulcerative colitis (Forearm)	0.263	0.736	0.000
M09.22 Juvenile arthritis in ulcerative colitis (Upper arm)	0.263	0.736	0.000
M09.21 Juvenile arthritis in ulcerative colitis (Shoulder region)	0.263	0.736	0.000
M09.20 Juvenile arthritis in ulcerative colitis (Multiple sites)	0.263	0.736	0.000
M09.89 Juvenile arthritis in other diseases classified elsewhere (Site unspecified)	0.263	0.736	0.000
M09.88 Juvenile arthritis in other diseases classified elsewhere (Other)	0.263	0.736	0.000
M09.87 Juvenile arthritis in other diseases classified elsewhere (Ankle and foot)	0.263	0.736	0.000
M09.86 Juvenile arthritis in other diseases classified elsewhere (Lower leg)	0.263	0.736	0.000
M09.85 Juvenile arthritis in other diseases classified elsewhere (Pelvic region and thigh)	0.263	0.736	0.000
M09.84 Juvenile arthritis in other diseases classified elsewhere (Hand)	0.263	0.736	0.000
M09.83 Juvenile arthritis in other diseases classified elsewhere (Forearm)	0.263	0.736	0.000
M09.82 Juvenile arthritis in other diseases classified elsewhere (Upper arm)	0.263	0.736	0.000
M09.81 Juvenile arthritis in other diseases classified elsewhere (Shoulder region)	0.263	0.736	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations