TreeWAS – Variant ID: rs2523404

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
G35 Multiple sclerosis	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.002	0.998
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.041	0.959
G37 Other demyelinating diseases of central nervous system	0.000	0.050	0.950
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.066	0.934
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.138	0.862
G36 Other acute disseminated demyelination	0.000	0.301	0.699
G37.5 Concentric sclerosis [Balo]	0.000	0.319	0.681
G37.4 Subacute necrotising myelitis	0.000	0.319	0.681
G37.2 Central pontine myelinolysis	0.000	0.319	0.681
G37.1 Central demyelination of corpus callosum	0.000	0.319	0.681
G37.0 Diffuse sclerosis	0.000	0.319	0.681
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.364	0.636
G36.0 Neuromyelitis optica [Devic]	0.000	0.487	0.512
G36.9 Acute disseminated demyelination, unspecified	0.000	0.499	0.501
G36.8 Other specified acute disseminated demyelination	0.000	0.499	0.501
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.499	0.501
E05.9 Thyrotoxicosis, unspecified	0.000	0.565	0.435
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.570	0.430
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.580	0.420
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.609	0.391
E05.5 Thyroid crisis or storm	0.000	0.692	0.308
E05.4 Thyrotoxicosis factitia	0.000	0.692	0.308
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.692	0.308
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.692	0.308
E05.8 Other thyrotoxicosis	0.000	0.716	0.283
K90 Intestinal malabsorption	0.000	0.721	0.279
E06 Thyroiditis	0.000	0.722	0.278
E00-E07 Disorders of thyroid gland	0.000	0.725	0.275
E06.3 Autoimmune thyroiditis	0.000	0.729	0.271
E06.9 Thyroiditis, unspecified	0.000	0.738	0.262
E06.5 Other chronic thyroiditis	0.000	0.787	0.212
K90.8 Other intestinal malabsorption	0.000	0.798	0.202
K90.3 Pancreatic steatorrhoea	0.000	0.800	0.200
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.800	0.200
K90.1 Tropical sprue	0.000	0.800	0.200
E06.4 Drug-induced thyroiditis	0.000	0.801	0.199
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.801	0.199
E06.0 Acute thyroiditis	0.000	0.801	0.199
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.803	0.197
E00 Congenital iodine-deficiency syndrome	0.000	0.803	0.197
K90.9 Intestinal malabsorption, unspecified	0.000	0.808	0.191
E06.1 Subacute thyroiditis	0.000	0.815	0.185
E07 Other disorders of thyroid	0.000	0.835	0.165
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.849	0.150
I84.9 Unspecified haemorrhoids without complication	0.147	0.853	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.858	0.141
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.858	0.141
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.858	0.141
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.858	0.141
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.858	0.141
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.858	0.141
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.858	0.141
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.858	0.141
E83 Disorders of mineral metabolism	0.000	0.860	0.140
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.872	0.128
E07.8 Other specified disorders of thyroid	0.000	0.874	0.126
E07.1 Dyshormogenetic goitre	0.000	0.881	0.118
E07.0 Hypersecretion of calcitonin	0.000	0.881	0.118
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.885	0.115
E83.8 Other disorders of mineral metabolism	0.000	0.900	0.100
E83.2 Disorders of zinc metabolism	0.000	0.900	0.100
E83.0 Disorders of copper metabolism	0.000	0.900	0.100
E83.3 Disorders of phosphorus metabolism	0.000	0.902	0.098
E03 Other hypothyroidism	0.000	0.904	0.095
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.906	0.094
M35.0 Sicca syndrome [Sjogren]	0.000	0.911	0.089
E83.5 Disorders of calcium metabolism	0.000	0.913	0.087
S06.3 Focal brain injury	0.000	0.925	0.074
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.928	0.072
E07.9 Disorder of thyroid, unspecified	0.000	0.929	0.071
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.931	0.069
E03.5 Myxoedema coma	0.000	0.931	0.069
E03.4 Atrophy of thyroid (acquired)	0.000	0.931	0.069
E03.3 Postinfectious hypothyroidism	0.000	0.931	0.069
E03.1 Congenital hypothyroidism without goitre	0.000	0.940	0.060
E03.8 Other specified hypothyroidism	0.000	0.941	0.059
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.946	0.054
S06 Intracranial injury	0.000	0.955	0.045
E04 Other non-toxic goitre	0.000	0.955	0.045
S06.5 Traumatic subdural haemorrhage	0.000	0.957	0.043
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.959	0.041
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.961	0.039
S06.1 Traumatic cerebral oedema	0.000	0.965	0.035
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.966	0.034
E04.0 Non-toxic diffuse goitre	0.000	0.967	0.033
S06.7 Intracranial injury with prolonged coma	0.000	0.967	0.033
E04.8 Other specified non-toxic goitre	0.000	0.968	0.032
S06.9 Intracranial injury, unspecified	0.000	0.968	0.032
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.969	0.031
S06.0 Concussion	0.000	0.970	0.030
S06.4 Epidural haemorrhage	0.000	0.972	0.028
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.972	0.028
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.973	0.027
K90-K93 Other diseases of the digestive system	0.000	0.973	0.027
S06.2 Diffuse brain injury	0.000	0.974	0.026
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.975	0.025
S06.8 Other intracranial injuries	0.000	0.975	0.025
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.976	0.024
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.976	0.024
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.977	0.023
M35 Other systemic involvement of connective tissue	0.000	0.977	0.023
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.977	0.022
E83.4 Disorders of magnesium metabolism	0.000	0.978	0.022
S06.01 Concussion (with open intracranial wound)	0.000	0.978	0.022
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.978	0.022
M35.7 Hypermobility syndrome	0.000	0.979	0.021
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.979	0.020
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.981	0.019
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.981	0.019
S06.00 Concussion (without open intracranial wound)	0.000	0.981	0.019
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.982	0.018
E04.9 Non-toxic goitre, unspecified	0.000	0.982	0.018
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.983	0.017
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.983	0.017
M35.5 Multifocal fibrosclerosis	0.000	0.983	0.017
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.983	0.017
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.984	0.016
M35.8 Other specified systemic involvement of connective tissue	0.000	0.984	0.016
M35.1 Other overlap syndromes	0.000	0.985	0.015
E04.2 Non-toxic multinodular goitre	0.000	0.985	0.015
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.015	0.985	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.985	0.015
M35.2 Behcet's disease	0.000	0.986	0.014
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.986	0.014
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.986	0.014
K93.1 Megacolon in Chagas' disease	0.000	0.986	0.014
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.986	0.014
I71 Aortic aneurysm and dissection	0.000	0.986	0.014
N76 Other inflammation of vagina and vulva	0.000	0.986	0.014
E70-E90 Metabolic disorders	0.000	0.986	0.014
E89.0 Postprocedural hypothyroidism	0.000	0.987	0.013
N76.8 Other specified inflammation of vagina and vulva	0.000	0.987	0.013
N76.3 Subacute and chronic vulvitis	0.000	0.987	0.013
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.987	0.013
E40-E46 Malnutrition	0.000	0.987	0.013
N76.2 Acute vulvitis	0.000	0.987	0.013
N76.0 Acute vaginitis	0.000	0.988	0.012
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.988	0.012
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.988	0.012
N76.4 Abscess of vulva	0.000	0.988	0.012
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.988	0.012
E89.2 Postprocedural hypoparathyroidism	0.000	0.988	0.012
E46 Unspecified protein-energy malnutrition	0.000	0.989	0.011
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.989	0.011
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.989	0.011
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.989	0.010
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.989	0.011
I73.9 Peripheral vascular disease, unspecified	0.000	0.990	0.010
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.990	0.010
N76.5 Ulceration of vagina	0.000	0.990	0.010
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.990	0.010
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.990	0.010
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.990	0.010
N76.1 Subacute and chronic vaginitis	0.000	0.990	0.010
E77 Disorders of glycoprotein metabolism	0.000	0.990	0.010
E76 Disorders of glycosaminoglycan metabolism	0.000	0.990	0.010
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.990	0.010
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.990	0.010
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.990	0.010
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.990	0.010
E70 Disorders of aromatic amino-acid metabolism	0.000	0.990	0.010
E89.4 Postprocedural ovarian failure	0.000	0.990	0.009
J15.1 Pneumonia due to Pseudomonas	0.010	0.990	0.000
E84 Cystic fibrosis	0.000	0.990	0.009
C50.9 Breast, unspecified	0.010	0.990	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.991	0.009
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.991	0.009
J15 Bacterial pneumonia, not elsewhere classified	0.009	0.991	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.991	0.009
E89.1 Postprocedural hypoinsulinaemia	0.000	0.991	0.009
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.991	0.009
E45 Retarded development following protein-energy malnutrition	0.000	0.991	0.009
E43 Unspecified severe protein-energy malnutrition	0.000	0.991	0.009
E42 Marasmic kwashiorkor	0.000	0.991	0.009
E41 Nutritional marasmus	0.000	0.991	0.009
E40 Kwashiorkor	0.000	0.991	0.009
E72 Other disorders of amino-acid metabolism	0.000	0.991	0.009
I73 Other peripheral vascular diseases	0.000	0.991	0.009
I72 Other aneurysm	0.000	0.991	0.009
I72.4 Aneurysm of artery of lower extremity	0.000	0.991	0.009
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.991	0.009
J15.0 Pneumonia due to Klebsiella pneumoniae	0.009	0.991	0.000
E73 Lactose intolerance	0.000	0.991	0.009
E79 Disorders of purine and pyrimidine metabolism	0.000	0.991	0.009
E74 Other disorders of carbohydrate metabolism	0.000	0.991	0.009
J15.2 Pneumonia due to staphylococcus	0.009	0.991	0.000
J15.4 Pneumonia due to other streptococci	0.008	0.991	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.991	0.008
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.992	0.008
E04.1 Non-toxic single thyroid nodule	0.000	0.992	0.008
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.992	0.008
E88 Other metabolic disorders	0.000	0.992	0.008
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.992	0.008
I71.0 Dissection of aorta [any part]	0.000	0.992	0.008
K91.1 Postgastric surgery syndromes	0.000	0.992	0.008
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.992	0.008
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.992	0.008
K91.5 Postcholecystectomy syndrome	0.000	0.992	0.008
E84.9 Cystic fibrosis, unspecified	0.000	0.992	0.008
I72.9 Aneurysm of unspecified site	0.000	0.992	0.008
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.008	0.992	0.000
I72.1 Aneurysm of artery of upper extremity	0.000	0.992	0.007
E71.3 Disorders of fatty-acid metabolism	0.000	0.993	0.007
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.993	0.007
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.993	0.007
E71.0 Maple-syrup-urine disease	0.000	0.993	0.007
E75.5 Other lipid storage disorders	0.000	0.993	0.007
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.993	0.007
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.993	0.007
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.993	0.007
E76.2 Other mucopolysaccharidoses	0.000	0.993	0.007
E76.1 Mucopolysaccharidosis, type II	0.000	0.993	0.007
E76.0 Mucopolysaccharidosis, type I	0.000	0.993	0.007
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.993	0.007
E77.8 Other disorders of glycoprotein metabolism	0.000	0.993	0.007
E77.1 Defects in glycoprotein degradation	0.000	0.993	0.007
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.993	0.007
N76.6 Ulceration of vulva	0.000	0.993	0.007
J15.5 Pneumonia due to Escherichia coli	0.007	0.993	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.993	0.007
I72.8 Aneurysm of other specified arteries	0.000	0.993	0.007
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.993	0.007
I70 Atherosclerosis	0.000	0.993	0.007
J15.8 Other bacterial pneumonia	0.007	0.993	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.993	0.007
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.993	0.007
E70.2 Disorders of tyrosine metabolism	0.000	0.993	0.007
E70.1 Other hyperphenylalaninaemias	0.000	0.993	0.007
E70.0 Classical phenylketonuria	0.000	0.993	0.007
E84.8 Cystic fibrosis with other manifestations	0.000	0.993	0.007
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.993	0.007
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.007	0.993	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.993	0.007
E89.5 Postprocedural testicular hypofunction	0.000	0.993	0.007
E75.6 Lipid storage disorder, unspecified	0.000	0.993	0.007
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.993	0.007
E75.3 Sphingolipidosis, unspecified	0.000	0.993	0.007
E75.1 Other gangliosidosis	0.000	0.993	0.007
E75.0 GM2 gangliosidosis	0.000	0.993	0.007
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.993	0.007
J15.3 Pneumonia due to streptococcus, group B	0.007	0.993	0.000
E44.1 Mild protein-energy malnutrition	0.000	0.993	0.007
E44.0 Moderate protein-energy malnutrition	0.000	0.993	0.007
E70.3 Albinism	0.000	0.993	0.007
E80.6 Other disorders of bilirubin metabolism	0.000	0.993	0.007
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.993	0.007
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.993	0.007
E72.5 Disorders of glycine metabolism	0.000	0.993	0.007
E72.4 Disorders of ornithine metabolism	0.000	0.993	0.007
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.993	0.007
E72.2 Disorders of urea cycle metabolism	0.000	0.993	0.007
G63.2 Diabetic polyneuropathy	0.007	0.993	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.993	0.007
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.993	0.007
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.005	0.993	0.002
I77 Other disorders of arteries and arterioles	0.000	0.993	0.007
E72.0 Disorders of amino-acid transport	0.000	0.993	0.006
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.993	0.007
E73.8 Other lactose intolerance	0.000	0.993	0.006
E73.1 Secondary lactase deficiency	0.000	0.993	0.006
E73.0 Congenital lactase deficiency	0.000	0.993	0.006
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.993	0.006
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.993	0.006
E79.1 Lesch-Nyhan syndrome	0.000	0.993	0.006
I74 Arterial embolism and thrombosis	0.000	0.993	0.007
I77.2 Rupture of artery	0.000	0.993	0.007
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.993	0.006
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.993	0.006
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.993	0.006
E74.2 Disorders of galactose metabolism	0.000	0.993	0.006
E74.1 Disorders of fructose metabolism	0.000	0.993	0.006
E80.1 Porphyria cutanea tarda	0.000	0.993	0.006
G60.0 Hereditary motor and sensory neuropathy	0.006	0.993	0.000
I72.2 Aneurysm of renal artery	0.000	0.993	0.006
E88.9 Metabolic disorder, unspecified	0.000	0.994	0.006
G63 Polyneuropathy in diseases classified elsewhere	0.005	0.994	0.001
E74.0 Glycogen storage disease	0.000	0.994	0.006
I79.1 Aortitis in diseases classified elsewhere	0.000	0.994	0.006
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.994	0.006
E27.1 Primary adrenocortical insufficiency	0.000	0.994	0.006
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.994	0.006
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.994	0.006
E80.5 Crigler-Najjar syndrome	0.000	0.994	0.006
E80.3 Defects of catalase and peroxydase	0.000	0.994	0.006
E80.0 Hereditary erythropoietic porphyria	0.000	0.994	0.006
I70.8 Atherosclerosis of other arteries	0.000	0.994	0.006
I74.8 Embolism and thrombosis of other arteries	0.000	0.994	0.006
E88.3 Tumour lysis syndrome	0.000	0.994	0.006
E75.2 Other sphingolipidosis	0.000	0.994	0.006
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.994	0.006
M35.3 Polymyalgia rheumatica	0.000	0.994	0.006
G60 Hereditary and idiopathic neuropathy	0.005	0.994	0.001
R31 Unspecified haematuria	0.006	0.994	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.994	0.006
E89.3 Postprocedural hypopituitarism	0.000	0.994	0.006
E88.2 Lipomatosis, not elsewhere classified	0.000	0.994	0.006
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.994	0.006
K50.9 Crohn's disease, unspecified	0.006	0.994	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.994	0.006
E50-E64 Other nutritional deficiencies	0.000	0.994	0.006
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.994	0.006
E88.8 Other specified metabolic disorders	0.000	0.994	0.006
J15.9 Bacterial pneumonia, unspecified	0.005	0.994	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.994	0.006
Z41 Procedures for purposes other than remedying health state	0.006	0.994	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.994	0.005
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.994	0.005
E73.9 Lactose intolerance, unspecified	0.000	0.994	0.005
I73.8 Other specified peripheral vascular diseases	0.000	0.994	0.005
E15 Nondiabetic hypoglycaemic coma	0.000	0.994	0.005
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.995	0.005
I70.0 Atherosclerosis of aorta	0.000	0.995	0.005
E80.2 Other porphyria	0.000	0.995	0.005
K91.3 Postoperative intestinal obstruction	0.000	0.995	0.005
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.995	0.005
I70.1 Atherosclerosis of renal artery	0.000	0.995	0.005
I70.9 Generalised and unspecified atherosclerosis	0.000	0.995	0.005
G30-G32 Other degenerative diseases of the nervous system	0.000	0.995	0.005
G61 Inflammatory polyneuropathy	0.005	0.995	0.001
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.995	0.005
I77.5 Necrosis of artery	0.000	0.995	0.005
I77.4 Coeliac artery compression syndrome	0.000	0.995	0.005
I77.3 Arterial fibromuscular dysplasia	0.000	0.995	0.005
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.995	0.005
G64 Other disorders of peripheral nervous system	0.003	0.995	0.002
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.995	0.005
E65-E68 Obesity and other hyperalimentation	0.000	0.995	0.005
I72.0 Aneurysm of carotid artery	0.000	0.995	0.005
G47.9 Sleep disorder, unspecified	0.000	0.995	0.005
G63.8 Polyneuropathy in other diseases classified elsewhere	0.004	0.995	0.001
G63.6 Polyneuropathy in other musculoskeletal disorders	0.004	0.995	0.001
G63.5 Polyneuropathy in systemic connective tissue disorders	0.004	0.995	0.001
G63.4 Polyneuropathy in nutritional deficiency	0.004	0.995	0.001
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.004	0.995	0.001
G63.1 Polyneuropathy in neoplastic disease	0.004	0.995	0.001
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.004	0.995	0.001
Chapter VI Diseases of the nervous system	0.000	0.995	0.005
I72.3 Aneurysm of iliac artery	0.000	0.995	0.005
G31.2 Degeneration of nervous system due to alcohol	0.000	0.995	0.005
I77.8 Other specified disorders of arteries and arterioles	0.000	0.995	0.005
E85 Amyloidosis	0.001	0.995	0.004
G31.0 Circumscribed brain atrophy	0.000	0.995	0.005
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.995	0.005
E51 Thiamine deficiency	0.000	0.995	0.005
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.995	0.005
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.995	0.005
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.995	0.005
Z41.8 Other procedures for purposes other than remedying health state	0.005	0.995	0.000
G62 Other polyneuropathies	0.002	0.995	0.003
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.995	0.005
G60.3 Idiopathic progressive neuropathy	0.004	0.995	0.001
G60.2 Neuropathy in association with hereditary ataxia	0.004	0.995	0.001
G60.1 Refsum's disease	0.004	0.995	0.001
S49 Other and unspecified injuries of shoulder and upper arm	0.000	0.995	0.005
K51.2 Ulcerative (chronic) proctitis	0.005	0.995	0.000
G61.0 Guillain-Barre syndrome	0.004	0.995	0.000
E55 Vitamin D deficiency	0.000	0.995	0.005
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.000	0.995	0.005
F01.9 Vascular dementia, unspecified	0.000	0.995	0.005
G31.8 Other specified degenerative diseases of nervous system	0.000	0.995	0.005
E56 Other vitamin deficiencies	0.000	0.995	0.004
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.995	0.005
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.995	0.004
B37.9 Candidiasis, unspecified	0.000	0.995	0.005
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.004	0.995	0.001
R03.1 Nonspecific low blood-pressure reading	0.000	0.995	0.005
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.995	0.004
E63 Other nutritional deficiencies	0.000	0.995	0.004
E50 Vitamin A deficiency	0.000	0.995	0.004
E60 Dietary zinc deficiency	0.000	0.995	0.004
E59 Dietary selenium deficiency	0.000	0.995	0.004
E52 Niacin deficiency [pellagra]	0.000	0.995	0.004
S46.3 Injury of muscle and tendon of triceps	0.000	0.996	0.004
E27 Other disorders of adrenal gland	0.000	0.996	0.004
Z41.3 Ear piercing	0.004	0.996	0.000
Z41.0 Hair transplant	0.004	0.996	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.996	0.004
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.996	0.004
Z41.9 Procedures for purposes other than remedying health state, unspecified	0.004	0.996	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.996	0.004
H73.8 Other specified disorders of tympanic membrane	0.004	0.996	0.000
I77.1 Stricture of artery	0.000	0.996	0.004
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.996	0.004
G61.8 Other inflammatory polyneuropathies	0.004	0.996	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.996	0.004
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.996	0.004
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.996	0.004
I77.6 Arteritis, unspecified	0.000	0.996	0.004
E54 Ascorbic acid deficiency	0.000	0.996	0.004
E20 Hypoparathyroidism	0.000	0.996	0.004
G60.8 Other hereditary and idiopathic neuropathies	0.003	0.996	0.001
G61.1 Serum neuropathy	0.003	0.996	0.001
E51.2 Wernicke's encephalopathy	0.000	0.996	0.004
K50.8 Other Crohn's disease	0.004	0.996	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.003	0.996	0.001
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.996	0.004
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.996	0.004
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.000	0.996	0.004
E67 Other hyperalimentation	0.000	0.996	0.004
E68 Sequelae of hyperalimentation	0.000	0.996	0.004
E58 Dietary calcium deficiency	0.000	0.996	0.004
E20.9 Hypoparathyroidism, unspecified	0.000	0.996	0.004
S49.8 Other specified injuries of shoulder and upper arm	0.000	0.996	0.004
E85.8 Other amyloidosis	0.001	0.996	0.003
E25 Adrenogenital disorders	0.000	0.996	0.004
I77.0 Arteriovenous fistula, acquired	0.000	0.996	0.004
E85.2 Heredofamilial amyloidosis, unspecified	0.001	0.996	0.003
E85.1 Neuropathic heredofamilial amyloidosis	0.001	0.996	0.003
E85.0 Nonneuropathic heredofamilial amyloidosis	0.001	0.996	0.003
G62.1 Alcoholic polyneuropathy	0.001	0.996	0.003
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.000	0.996	0.004
E51.9 Thiamine deficiency, unspecified	0.000	0.996	0.003
E51.8 Other manifestations of thiamine deficiency	0.000	0.996	0.003
E51.1 Beriberi	0.000	0.996	0.003
K50 Crohn's disease [regional enteritis]	0.004	0.996	0.000
G62.2 Polyneuropathy due to other toxic agents	0.002	0.996	0.002
E55.9 Vitamin D deficiency, unspecified	0.000	0.996	0.004
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.996	0.004
E56.1 Deficiency of vitamin K	0.000	0.996	0.003
S49.7 Multiple injuries of shoulder and upper arm	0.000	0.996	0.003
E55.0 Rickets, active	0.000	0.996	0.003
G62.9 Polyneuropathy, unspecified	0.000	0.996	0.004
E53 Deficiency of other B group vitamins	0.000	0.996	0.004
E56.9 Vitamin deficiency, unspecified	0.000	0.996	0.003
E56.8 Deficiency of other vitamins	0.000	0.996	0.003
E56.0 Deficiency of vitamin E	0.000	0.996	0.003
E23 Hypofunction and other disorders of pituitary gland	0.000	0.996	0.004
C32.0 Glottis	0.004	0.996	0.000
I15.1 Hypertension secondary to other renal disorders	0.004	0.996	0.000
E50.9 Vitamin A deficiency, unspecified	0.000	0.996	0.003
E50.8 Other manifestations of vitamin A deficiency	0.000	0.996	0.003
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.996	0.003
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.996	0.003
E50.5 Vitamin A deficiency with night blindness	0.000	0.996	0.003
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.996	0.003
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.996	0.003
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.996	0.003
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.996	0.003
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.996	0.003
E63.9 Nutritional deficiency, unspecified	0.000	0.996	0.003
E63.8 Other specified nutritional deficiencies	0.000	0.996	0.003
E63.1 Imbalance of constituents of food intake	0.000	0.996	0.003
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.996	0.003
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.996	0.003
E64.8 Sequelae of other nutritional deficiencies	0.000	0.996	0.003
E64.3 Sequelae of rickets	0.000	0.996	0.003
E64.2 Sequelae of vitamin C deficiency	0.000	0.996	0.003
E64.1 Sequelae of vitamin A deficiency	0.000	0.996	0.003
E64.0 Sequelae of protein-energy malnutrition	0.000	0.996	0.003
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.997	0.003
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.997	0.003
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.997	0.003
E80.4 Gilbert's syndrome	0.000	0.997	0.003
E23.6 Other disorders of pituitary gland	0.000	0.997	0.003
G30 Alzheimer's disease	0.000	0.997	0.003
Z42.1 Follow-up care involving plastic surgery of breast	0.003	0.997	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.997	0.003
Z41.2 Routine and ritual circumcision	0.003	0.997	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.997	0.003
E27.0 Other adrenocortical overactivity	0.000	0.997	0.003
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.997	0.003
E32 Diseases of thymus	0.000	0.997	0.003
E31 Polyglandular dysfunction	0.000	0.997	0.003
E30 Disorders of puberty, not elsewhere classified	0.000	0.997	0.003
S46.1 Injury of muscle and tendon of long head of biceps	0.000	0.997	0.003
I78 Diseases of capillaries	0.000	0.997	0.003
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.997	0.003
G62.0 Drug-induced polyneuropathy	0.002	0.997	0.002
E20.8 Other hypoparathyroidism	0.000	0.997	0.003
E20.1 Pseudohypoparathyroidism	0.000	0.997	0.003
E20.0 Idiopathic hypoparathyroidism	0.000	0.997	0.003
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.997	0.003
E85.3 Secondary systemic amyloidosis	0.001	0.997	0.002
H21.8 Other specified disorders of iris and ciliary body	0.003	0.997	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.997	0.003
G30.0 Alzheimer's disease with early onset	0.000	0.997	0.003
H53.2 Diplopia	0.000	0.997	0.003
E67.8 Other specified hyperalimentation	0.000	0.997	0.003
E67.3 Hypervitaminosis D	0.000	0.997	0.003
E67.2 Megavitamin-B6 syndrome	0.000	0.997	0.003
E67.1 Hypercarotenaemia	0.000	0.997	0.003
E67.0 Hypervitaminosis A	0.000	0.997	0.003
I73.0 Raynaud's syndrome	0.000	0.997	0.003
E25.9 Adrenogenital disorder, unspecified	0.000	0.997	0.003
E25.8 Other adrenogenital disorders	0.000	0.997	0.003
E26 Hyperaldosteronism	0.000	0.997	0.003
B37 Candidiasis	0.000	0.997	0.003
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.997	0.003
I15.0 Renovascular hypertension	0.003	0.997	0.000
E27.2 Addisonian crisis	0.000	0.997	0.003
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.997	0.003
E23.7 Disorder of pituitary gland, unspecified	0.000	0.997	0.003
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.997	0.003
E85.4 Organ-limited amyloidosis	0.001	0.997	0.002
B37.3 Candidiasis of vulva and vagina	0.000	0.997	0.003
G70-G73 Diseases of myoneural junction and muscle	0.000	0.997	0.003
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.997	0.003
E23.1 Drug-induced hypopituitarism	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations