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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2523452
log Bayes Factor = 81.6495
Chromosome 6   position 31,368,540  (GRCh37) Explore rs2523452 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
M45 Ankylosing spondylitis
0.998 0.002 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.998 0.002 0.000
E03 Other hypothyroidism
0.000 0.002 0.998
M07.30 Other psoriatic arthropathies (Multiple sites)
0.998 0.002 0.000
M07.3 Other psoriatic arthropathies
0.997 0.003 0.000
E27 Other disorders of adrenal gland
0.000 0.003 0.997
E03.9 Hypothyroidism, unspecified
0.000 0.003 0.997
E27.1 Primary adrenocortical insufficiency
0.000 0.003 0.997
E10.3 With ophthalmic complications
0.000 0.003 0.997
E20-E35 Disorders of other endocrine glands
0.000 0.004 0.996
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.004 0.996
M07.39 Other psoriatic arthropathies (Site unspecified)
0.994 0.006 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.007 0.993
L40.0 Psoriasis vulgaris
0.993 0.007 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.010 0.990
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.012 0.988
E10.1 With ketoacidosis
0.000 0.013 0.987
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.042 0.958
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.045 0.955
E10.4 With neurological complications
0.000 0.051 0.949
E05.9 Thyrotoxicosis, unspecified
0.000 0.071 0.929
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.928 0.072 0.000
E10.0 With coma
0.000 0.081 0.919
E14 Unspecified diabetes mellitus
0.000 0.099 0.901
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.106 0.894
E27.2 Addisonian crisis
0.000 0.128 0.872
E20 Hypoparathyroidism
0.000 0.137 0.863
M07.34 Other psoriatic arthropathies (Hand)
0.859 0.141 0.000
L40.4 Guttate psoriasis
0.847 0.153 0.000
K90 Intestinal malabsorption
0.000 0.154 0.846
E14.9 Without complications
0.000 0.175 0.825
E10.2 With renal complications
0.000 0.178 0.822
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.808 0.192 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.206 0.794
M07.38 Other psoriatic arthropathies (Other)
0.790 0.209 0.000
L40.1 Generalised pustular psoriasis
0.778 0.222 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.774 0.226 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.232 0.768
M45.X6 Ankylosing spondylitis (Lumbar region)
0.767 0.233 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.240 0.760
M45.X2 Ankylosing spondylitis (Cervical region)
0.760 0.240 0.000
L40-L45 Papulosquamous disorders
0.755 0.245 0.000
E10.5 With peripheral circulatory complications
0.000 0.253 0.747
M07.31 Other psoriatic arthropathies (Shoulder region)
0.746 0.253 0.000
L40.8 Other psoriasis
0.739 0.261 0.000
E10.6 With other specified complications
0.000 0.263 0.737
K90.8 Other intestinal malabsorption
0.000 0.276 0.724
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.277 0.723
E10.7 With multiple complications
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.716
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.716 0.284 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.716 0.284 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.716 0.284 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.716 0.284 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.716 0.284 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.716 0.284 0.000
E03.5 Myxoedema coma
0.000 0.285 0.715
E03.4 Atrophy of thyroid (acquired)
0.000 0.285 0.715
E03.3 Postinfectious hypothyroidism
0.000 0.285 0.715
M07.33 Other psoriatic arthropathies (Forearm)
0.715 0.285 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.715 0.285 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.285 0.715
E27.0 Other adrenocortical overactivity
0.000 0.285 0.715
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.286 0.714
E32 Diseases of thymus
0.000 0.286 0.714
E31 Polyglandular dysfunction
0.000 0.286 0.714
E30 Disorders of puberty, not elsewhere classified
0.000 0.286 0.714
E15 Nondiabetic hypoglycaemic coma
0.000 0.286 0.714
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.288 0.712
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.288 0.712
E16.4 Abnormal secretion of gastrin
0.000 0.288 0.712
E16.3 Increased secretion of glucagon
0.000 0.288 0.712
E27.8 Other specified disorders of adrenal gland
0.000 0.291 0.709
E05.5 Thyroid crisis or storm
0.000 0.292 0.708
E05.4 Thyrotoxicosis factitia
0.000 0.292 0.708
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.292 0.708
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.292 0.708
E03.1 Congenital hypothyroidism without goitre
0.000 0.297 0.703
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.302 0.698
E14.6 With other specified complications
0.000 0.303 0.697
L42 Pityriasis rosea
0.695 0.305 0.000
E40-E46 Malnutrition
0.000 0.307 0.693
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.307 0.693
E23 Hypofunction and other disorders of pituitary gland
0.000 0.309 0.691
E25 Adrenogenital disorders
0.000 0.312 0.688
L40.3 Pustulosis palmaris et plantaris
0.685 0.315 0.000
E34 Other endocrine disorders
0.000 0.319 0.681
E07 Other disorders of thyroid
0.000 0.322 0.678
E14.1 With ketoacidosis
0.000 0.324 0.676
E10.8 With unspecified complications
0.000 0.332 0.668
E14.5 With peripheral circulatory complications
0.000 0.343 0.657
E14.2 Withrenal complications
0.000 0.348 0.652
E14.7 With multiple complications
0.000 0.354 0.646
E14.0 With coma
0.000 0.354 0.646
E14.3 With ophthalmic complications
0.000 0.355 0.645
E26 Hyperaldosteronism
0.000 0.356 0.644
E22 Hyperfunction of pituitary gland
0.000 0.365 0.634
E03.8 Other specified hypothyroidism
0.000 0.366 0.634
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.381 0.619
E20.8 Other hypoparathyroidism
0.000 0.381 0.619
E20.1 Pseudohypoparathyroidism
0.000 0.381 0.619
E20.0 Idiopathic hypoparathyroidism
0.000 0.381 0.619
E14.8 With unspecified complications
0.000 0.383 0.617
E05.8 Other thyrotoxicosis
0.000 0.384 0.615
E28 Ovarian dysfunction
0.000 0.393 0.607
K90.3 Pancreatic steatorrhoea
0.000 0.393 0.607
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.393 0.607
K90.1 Tropical sprue
0.000 0.393 0.607
E13 Other specified diabetes mellitus
0.000 0.394 0.605
E23.2 Diabetes insipidus
0.000 0.397 0.603
L41 Parapsoriasis
0.596 0.404 0.000
E14.4 With neurological complications
0.000 0.416 0.584
E07.8 Other specified disorders of thyroid
0.000 0.423 0.577
E34.9 Endocrine disorder, unspecified
0.000 0.442 0.558
E23.7 Disorder of pituitary gland, unspecified
0.000 0.447 0.552
E06 Thyroiditis
0.000 0.451 0.549
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.458 0.542
L44 Other papulosquamous disorders
0.541 0.459 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.541 0.459 0.000
E29 Testicular dysfunction
0.000 0.471 0.529
E34.8 Other specified endocrine disorders
0.000 0.478 0.522
L43 Lichen planus
0.519 0.481 0.000
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.488 0.512
E30.8 Other disorders of puberty
0.000 0.488 0.512
E30.1 Precocious puberty
0.000 0.488 0.512
E30.0 Delayed puberty
0.000 0.488 0.512
E31.9 Polyglandular dysfunction, unspecified
0.000 0.488 0.512
E31.8 Other polyglandular dysfunction
0.000 0.488 0.512
E31.1 Polyglandular hyperfunction
0.000 0.488 0.512
E31.0 Autoimmune polyglandular failure
0.000 0.488 0.512
E32.9 Disease of thymus, unspecified
0.000 0.488 0.512
E32.8 Other diseases of thymus
0.000 0.488 0.512
E32.1 Abscess of thymus
0.000 0.488 0.512
E32.0 Persistent hyperplasia of thymus
0.000 0.488 0.512
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.488 0.512
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.488 0.512
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.488 0.512
E28.3 Primary ovarian failure
0.000 0.500 0.500
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.503 0.497
E45 Retarded development following protein-energy malnutrition
0.000 0.503 0.497
E43 Unspecified severe protein-energy malnutrition
0.000 0.503 0.497
E42 Marasmic kwashiorkor
0.000 0.503 0.497
E41 Nutritional marasmus
0.000 0.503 0.497
E40 Kwashiorkor
0.000 0.503 0.497
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.504 0.496
E23.1 Drug-induced hypopituitarism
0.000 0.504 0.496
E27.9 Disorder of adrenal gland, unspecified
0.000 0.504 0.495
E16.1 Other hypoglycaemia
0.001 0.505 0.494
E65-E68 Obesity and other hyperalimentation
0.000 0.506 0.494
E25.9 Adrenogenital disorder, unspecified
0.000 0.506 0.493
E25.8 Other adrenogenital disorders
0.000 0.506 0.493
E22.1 Hyperprolactinaemia
0.000 0.511 0.489
E34.5 Androgen resistance syndrome
0.000 0.512 0.488
E34.4 Constitutional tall stature
0.000 0.512 0.488
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.512 0.488
E34.1 Other hypersecretion of intestinal hormones
0.000 0.512 0.488
E50-E64 Other nutritional deficiencies
0.000 0.513 0.487
E07.1 Dyshormogenetic goitre
0.000 0.514 0.486
E07.0 Hypersecretion of calcitonin
0.000 0.514 0.486
L41.1 Pityriasis lichenoides chronica
0.482 0.518 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.528 0.472
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.532 0.467
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.467 0.533 0.000
E26.8 Other hyperaldosteronism
0.000 0.538 0.462
E26.1 Secondary hyperaldosteronism
0.000 0.538 0.462
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.545 0.455
E22.8 Other hyperfunction of pituitary gland
0.000 0.545 0.455
M07 Psoriatic and enteropathic arthropathies
0.450 0.550 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.556 0.443
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.441 0.559 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.565 0.435
E28.8 Other ovarian dysfunction
0.000 0.565 0.435
E28.1 Androgen excess
0.000 0.565 0.435
E28.0 Oestrogen excess
0.000 0.565 0.435
E13.8 With unspecified complications
0.000 0.566 0.434
E13.7 With multiple complications
0.000 0.566 0.434
E13.6 With other specified complications
0.000 0.566 0.434
E13.5 With peripheral circulatory complications
0.000 0.566 0.434
E13.4 With neurological complications
0.000 0.566 0.434
E13.3 With ophthalmic complications
0.000 0.566 0.434
E13.2 With renal complications
0.000 0.566 0.434
E13.1 With ketoacidosis
0.000 0.566 0.434
E13.0 With coma
0.000 0.566 0.434
E06.3 Autoimmune thyroiditis
0.000 0.567 0.433
L41.9 Parapsoriasis, unspecified
0.427 0.573 0.000
L41.8 Other parapsoriasis
0.427 0.573 0.000
L41.5 Retiform parapsoriasis
0.427 0.573 0.000
L41.4 Large plaque parapsoriasis
0.427 0.573 0.000
L41.3 Small plaque parapsoriasis
0.427 0.573 0.000
L41.2 Lymphomatoid papulosis
0.427 0.573 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.427 0.573 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.581 0.419
E23.6 Other disorders of pituitary gland
0.000 0.581 0.419
E26.0 Primary hyperaldosteronism
0.000 0.584 0.416
E34.3 Short stature, not elsewhere classified
0.000 0.590 0.410
C82.0 Small cleaved cell, follicular
0.405 0.595 0.000
E53 Deficiency of other B group vitamins
0.000 0.600 0.400
E06.4 Drug-induced thyroiditis
0.000 0.606 0.393
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.606 0.393
E06.0 Acute thyroiditis
0.000 0.606 0.393
L44.9 Papulosquamous disorder, unspecified
0.388 0.612 0.000
L44.8 Other specified papulosquamous disorders
0.388 0.612 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.388 0.612 0.000
L44.3 Lichen ruber moniliformis
0.388 0.612 0.000
L44.2 Lichen striatus
0.388 0.612 0.000
L44.1 Lichen nitidus
0.388 0.612 0.000
L44.0 Pityriasis rubra pilaris
0.388 0.612 0.000
L43.9 Lichen planus, unspecified
0.387 0.613 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.383 0.617 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.621 0.379
E29.8 Other testicular dysfunction
0.000 0.621 0.379
E29.0 Testicular hyperfunction
0.000 0.621 0.379
E34.0 Carcinoid syndrome
0.000 0.624 0.375
E24 Cushing's syndrome
0.001 0.626 0.373
L43.3 Subacute (active) lichen planus
0.372 0.628 0.000
L43.2 Lichenoid drug reaction
0.372 0.628 0.000
L43.1 Bullous lichen planus
0.372 0.628 0.000
L43.0 Hypertrophic lichen planus
0.372 0.628 0.000
E06.5 Other chronic thyroiditis
0.000 0.631 0.369
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.632 0.367
E51 Thiamine deficiency
0.000 0.637 0.363
E65 Localised adiposity
0.000 0.638 0.362
C82.1 Mixed small cleaved and large cell, follicular
0.358 0.642 0.000
C82.4 Follicular lymphoma grade IIIb
0.357 0.643 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.644 0.356
E44.0 Moderate protein-energy malnutrition
0.000 0.644 0.356
E67 Other hyperalimentation
0.000 0.646 0.354
E68 Sequelae of hyperalimentation
0.000 0.646 0.354
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.650 0.349
E63 Other nutritional deficiencies
0.000 0.650 0.349
E50 Vitamin A deficiency
0.000 0.650 0.349
E60 Dietary zinc deficiency
0.000 0.650 0.349
E59 Dietary selenium deficiency
0.000 0.650 0.349
E54 Ascorbic acid deficiency
0.000 0.650 0.349
E52 Niacin deficiency [pellagra]
0.000 0.650 0.349
E56 Other vitamin deficiencies
0.000 0.655 0.345
C82.3 Follicular lymphoma grade IIIa
0.344 0.656 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.669 0.331
L43.8 Other lichen planus
0.331 0.669 0.000
C82.2 Large cell, follicular
0.325 0.674 0.000
M07.6 Other enteropathic arthropathies
0.323 0.677 0.000
M07.5 Arthropathy in ulcerative colitis
0.323 0.677 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.323 0.677 0.000
M07.2 Psoriatic spondylitis
0.323 0.677 0.000
M07.1 Arthritis mutilans
0.323 0.677 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.323 0.677 0.000
E13.9 Without complications
0.000 0.677 0.323
C82.6 Cutaneous follicle centre lymphoma
0.316 0.684 0.000
C82.5 Diffuse follicle centre lymphoma
0.316 0.684 0.000
E06.9 Thyroiditis, unspecified
0.000 0.691 0.308
E06.1 Subacute thyroiditis
0.001 0.693 0.307
E58 Dietary calcium deficiency
0.000 0.699 0.301
E53.9 Vitamin B deficiency, unspecified
0.000 0.703 0.297
E53.1 Pyridoxine deficiency
0.000 0.713 0.287
E53.0 Riboflavin deficiency
0.000 0.713 0.287
E51.2 Wernicke's encephalopathy
0.000 0.726 0.274
E24.8 Other Cushing's syndrome
0.001 0.732 0.267
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.732 0.267
E24.3 Ectopic ACTH syndrome
0.001 0.732 0.267
E24.1 Nelson's syndrome
0.001 0.732 0.267
E55 Vitamin D deficiency
0.000 0.738 0.262
E51.9 Thiamine deficiency, unspecified
0.000 0.739 0.260
E51.8 Other manifestations of thiamine deficiency
0.000 0.739 0.260
E51.1 Beriberi
0.000 0.739 0.260
E67.8 Other specified hyperalimentation
0.000 0.746 0.254
E67.3 Hypervitaminosis D
0.000 0.746 0.254
E67.2 Megavitamin-B6 syndrome
0.000 0.746 0.254
E67.1 Hypercarotenaemia
0.000 0.746 0.254
E67.0 Hypervitaminosis A
0.000 0.746 0.254
E50.9 Vitamin A deficiency, unspecified
0.000 0.749 0.251
E50.8 Other manifestations of vitamin A deficiency
0.000 0.749 0.251
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.749 0.251
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.749 0.251
E50.5 Vitamin A deficiency with night blindness
0.000 0.749 0.251
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.749 0.251
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.749 0.251
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.749 0.251
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.749 0.251
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.749 0.251
E63.9 Nutritional deficiency, unspecified
0.000 0.749 0.251
E63.8 Other specified nutritional deficiencies
0.000 0.749 0.251
E63.1 Imbalance of constituents of food intake
0.000 0.749 0.251
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.749 0.251
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.749 0.251
E64.8 Sequelae of other nutritional deficiencies
0.000 0.749 0.251
E64.3 Sequelae of rickets
0.000 0.749 0.251
E64.2 Sequelae of vitamin C deficiency
0.000 0.749 0.251
E64.1 Sequelae of vitamin A deficiency
0.000 0.749 0.251
E64.0 Sequelae of protein-energy malnutrition
0.000 0.749 0.251
E24.2 Drug-induced Cushing's syndrome
0.001 0.749 0.249
E56.9 Vitamin deficiency, unspecified
0.000 0.752 0.247
E56.8 Deficiency of other vitamins
0.000 0.752 0.247
E56.0 Deficiency of vitamin E
0.000 0.752 0.247
E56.1 Deficiency of vitamin K
0.000 0.757 0.243
E07.9 Disorder of thyroid, unspecified
0.000 0.761 0.239
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.232 0.768 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.232 0.768 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.232 0.768 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.232 0.768 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.232 0.768 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.232 0.768 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.232 0.768 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.232 0.768 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.232 0.768 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.232 0.768 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.232 0.768 0.000
M07.18 Arthritis mutilans (Other)
0.232 0.768 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.232 0.768 0.000
M07.16 Arthritis mutilans (Lower leg)
0.232 0.768 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.232 0.768 0.000
M07.14 Arthritis mutilans (Hand)
0.232 0.768 0.000
M07.13 Arthritis mutilans (Forearm)
0.232 0.768 0.000
M07.12 Arthritis mutilans (Upper arm)
0.232 0.768 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.232 0.768 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.232 0.768 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.232 0.768 0.000
M07.28 Psoriatic spondylitis (Other)
0.232 0.768 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.232 0.768 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.232 0.768 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.232 0.768 0.000
M07.24 Psoriatic spondylitis (Hand)
0.232 0.768 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.232 0.768 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.232 0.768 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.232 0.768 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.232 0.768 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.232 0.768 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.232 0.768 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.232 0.768 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.232 0.768 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.232 0.768 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.232 0.768 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.232 0.768 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.232 0.768 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.232 0.768 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.232 0.768 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.232 0.768 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.232 0.768 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.232 0.768 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.232 0.768 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.232 0.768 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.232 0.768 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.232 0.768 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.232 0.768 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.232 0.768 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.232 0.768 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.232 0.768 0.000
M07.68 Other enteropathic arthropathies (Other)
0.232 0.768 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.232 0.768 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.232 0.768 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.232 0.768 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.232 0.768 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.232 0.768 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.232 0.768 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.232 0.768 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.232 0.768 0.000
E24.0 Pituitary-dependent Cushing's disease
0.001 0.785 0.214
E23.0 Hypopituitarism
0.000 0.795 0.204
E61 Deficiency of other nutrient elements
0.001 0.796 0.203
E29.1 Testicular hypofunction
0.001 0.806 0.194
E55.0 Rickets, active
0.000 0.812 0.188
E04 Other non-toxic goitre
0.000 0.819 0.180
E11 Non-insulin-dependent diabetes mellitus
0.000 0.825 0.175
E28.2 Polycystic ovarian syndrome
0.001 0.842 0.157
E11.5 With peripheral circulatory complications
0.000 0.847 0.153
E61.9 Deficiency of nutrient element, unspecified
0.001 0.854 0.146
E61.8 Deficiency of other specified nutrient elements
0.001 0.854 0.146
E61.7 Deficiency of multiple nutrient elements
0.001 0.854 0.146
E61.6 Vanadium deficiency
0.001 0.854 0.146
E61.5 Molybdenum deficiency
0.001 0.854 0.146
E61.4 Chromium deficiency
0.001 0.854 0.146
E61.3 Manganese deficiency
0.001 0.854 0.146
E61.0 Copper deficiency
0.001 0.854 0.146
E04.0 Non-toxic diffuse goitre
0.000 0.864 0.136
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.867 0.133
E11.3 With ophthalmic complications
0.000 0.869 0.131
E04.8 Other specified non-toxic goitre
0.000 0.870 0.130
E61.2 Magnesium deficiency
0.001 0.872 0.127
E11.7 With multiple complications
0.000 0.874 0.126
E24.9 Cushing's syndrome, unspecified
0.002 0.878 0.120
M45-M49 Spondylopathies
0.120 0.880 0.000
E11.8 With unspecified complications
0.000 0.881 0.119
E11.1 With ketoacidosis
0.000 0.887 0.113
E11.0 With coma
0.000 0.888 0.112
E11.6 With other specified complications
0.000 0.891 0.109
E66 Obesity
0.000 0.892 0.108
E55.9 Vitamin D deficiency, unspecified
0.000 0.899 0.100
E04.1 Non-toxic single thyroid nodule
0.000 0.901 0.099
D69.6 Thrombocytopenia, unspecified
0.000 0.901 0.099
D69 Purpura and other haemorrhagic conditions
0.000 0.902 0.098
E11.2 With renal complications
0.000 0.903 0.097
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.904 0.096
E21.4 Other specified disorders of parathyroid gland
0.000 0.913 0.087
D69.5 Secondary thrombocytopenia
0.000 0.913 0.087
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.919 0.081
G35 Multiple sclerosis
0.000 0.920 0.080
E21.2 Other hyperparathyroidism
0.000 0.920 0.079
E66.0 Obesity due to excess calories
0.000 0.921 0.079
E66.1 Drug-induced obesity
0.000 0.922 0.078
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.922 0.077
D69.0 Allergic purpura
0.000 0.923 0.077
D69.4 Other primary thrombocytopenia
0.000 0.924 0.076
D69.2 Other nonthrombocytopenic purpura
0.000 0.925 0.075
M49 Spondylopathies in diseases classified elsewhere
0.075 0.925 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.927 0.073
D69.8 Other specified haemorrhagic conditions
0.000 0.930 0.070
E21.3 Hyperparathyroidism, unspecified
0.000 0.931 0.069
D69.1 Qualitative platelet defects
0.000 0.933 0.067
K90-K93 Other diseases of the digestive system
0.000 0.933 0.067
E11.4 With neurological complications
0.000 0.935 0.065
M46 Other inflammatory spondylopathies
0.065 0.935 0.000
M48 Other spondylopathies
0.064 0.936 0.000
D69.9 Haemorrhagic condition, unspecified
0.000 0.940 0.060
M05-M14 Inflammatory polyarthropathies
0.058 0.942 0.000
K59.8 Other specified functional intestinal disorders
0.057 0.943 0.000
M46.4 Discitis, unspecified
0.055 0.945 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.054 0.946 0.000
M49.4 Neuropathic spondylopathy
0.054 0.946 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.054 0.946 0.000
M49.2 Enterobacterial spondylitis
0.054 0.946 0.000
M49.1 Brucella spondylitis
0.054 0.946 0.000
M49.0 Tuberculosis of spine
0.054 0.946 0.000
M48.9 Spondylopathy, unspecified
0.053 0.947 0.000
E61.1 Iron deficiency
0.001 0.950 0.049
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.952 0.048
M48.8 Other specified spondylopathies
0.048 0.952 0.000
M46.8 Other specified inflammatory spondylopathies
0.047 0.953 0.000
M46.5 Other infective spondylopathies
0.047 0.953 0.000
M46.2 Osteomyelitis of vertebra
0.047 0.953 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.047 0.953 0.000
M48.4 Fatigue fracture of vertebra
0.046 0.954 0.000
M48.3 Traumatic spondylopathy
0.046 0.954 0.000
M48.2 Kissing spine
0.046 0.954 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.046 0.954 0.000
M11 Other crystal arthropathies
0.046 0.954 0.000
M08 Juvenile arthritis
0.045 0.955 0.000
M47 Spondylosis
0.045 0.955 0.000
J33.0 Polyp of nasal cavity
0.000 0.956 0.044
M48.99 Spondylopathy, unspecified (Site unspecified)
0.044 0.956 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.043 0.956 0.000
M35.0 Sicca syndrome [Sjogren]
0.000 0.956 0.044
M49.5 Collapsed vertebra in diseases classified elsewhere
0.042 0.957 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.042 0.958 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.042 0.958 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.042 0.958 0.000
M46.0 Spinal enthesopathy
0.042 0.958 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.042 0.958 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.042 0.958 0.000
M48.92 Spondylopathy, unspecified (Cervical region)
0.042 0.958 0.000
M46.42 Discitis, unspecified (Cervical region)
0.041 0.958 0.000
H20.9 Iridocyclitis, unspecified
0.041 0.959 0.000
M35 Other systemic involvement of connective tissue
0.000 0.959 0.041
M35.3 Polymyalgia rheumatica
0.000 0.959 0.041
M47.8 Other spondylosis
0.041 0.959 0.000
M46.40 Discitis, unspecified (Multiple sites in spine)
0.040 0.960 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.040 0.960 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.040 0.960 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.040 0.960 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.040 0.960 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.040 0.960 0.000
M47.82 Other spondylosis (Cervical region)
0.039 0.961 0.000
M48.87 Other specified spondylopathies (Lumbosacral region)
0.039 0.961 0.000
M49.09 Tuberculosis of spine (Site unspecified)
0.039 0.961 0.000
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.039 0.961 0.000
M49.07 Tuberculosis of spine (Lumbosacral region)
0.039 0.961 0.000
M49.06 Tuberculosis of spine (Lumbar region)
0.039 0.961 0.000
M49.05 Tuberculosis of spine (Thoracolumbar region)
0.039 0.961 0.000
M49.04 Tuberculosis of spine (Thoracic region)
0.039 0.961 0.000
M49.03 Tuberculosis of spine (Cervicothoracic region)
0.039 0.961 0.000
M49.02 Tuberculosis of spine (Cervical region)
0.039 0.961 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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