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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2523476
log Bayes Factor = 8.49322
Chromosome 6   position 31,361,424  (GRCh37) Explore rs2523476 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.001 0.999
# Top node
0.000 0.002 0.998
L40-L45 Papulosquamous disorders
0.000 0.003 0.997
L40 Psoriasis
0.000 0.004 0.996
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.005 0.995
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.007 0.993
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.008 0.992
E65-E68 Obesity and other hyperalimentation
0.000 0.010 0.990
L40.5 Arthropathic psoriasis
0.000 0.012 0.988
L57.0 Actinic keratosis
0.000 0.014 0.986
M06.9 Rheumatoid arthritis, unspecified
0.000 0.015 0.985
D50-D53 Nutritional anaemias
0.000 0.015 0.985
M06 Other rheumatoid arthritis
0.000 0.016 0.984
L40.9 Psoriasis, unspecified
0.000 0.016 0.984
M05-M14 Inflammatory polyarthropathies
0.000 0.017 0.983
E66 Obesity
0.000 0.017 0.983
D50 Iron deficiency anaemia
0.000 0.018 0.982
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.018 0.982
D50.9 Iron deficiency anaemia, unspecified
0.000 0.020 0.980
E66.8 Other obesity
0.000 0.020 0.980
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.023 0.977
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.031 0.969
Chapter I Certain infectious and parasitic diseases
0.000 0.035 0.965
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.035 0.965
B35-B49 Mycoses
0.000 0.041 0.959
B37 Candidiasis
0.000 0.042 0.958
B37.8 Candidiasis of other sites
0.000 0.045 0.955
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.046 0.954
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.058 0.942
E70-E90 Metabolic disorders
0.000 0.074 0.926
B37.0 Candidal stomatitis
0.000 0.087 0.913
B25-B34 Other viral diseases
0.000 0.089 0.911
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.092 0.908
Chapter VIII Diseases of the ear and mastoid process
0.000 0.093 0.907
E06 Thyroiditis
0.000 0.093 0.906
M07 Psoriatic and enteropathic arthropathies
0.000 0.094 0.906
M45-M49 Spondylopathies
0.000 0.097 0.903
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.098 0.902
L20-L30 Dermatitis and eczema
0.000 0.100 0.900
M45 Ankylosing spondylitis
0.000 0.108 0.892
E10-E14 Diabetes mellitus
0.000 0.115 0.885
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.115 0.885
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.118 0.882
B34 Viral infection of unspecified site
0.000 0.134 0.866
E10 Insulin-dependent diabetes mellitus
0.000 0.136 0.864
H65-H75 Diseases of middle ear and mastoid
0.000 0.142 0.858
D68 Other coagulation defects
0.000 0.147 0.853
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.148 0.852
M07.3 Other psoriatic arthropathies
0.000 0.149 0.851
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.155 0.845
H72 Perforation of tympanic membrane
0.000 0.160 0.840
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.163 0.837
M35 Other systemic involvement of connective tissue
0.000 0.166 0.834
M20-M25 Other joint disorders
0.000 0.169 0.831
M35.3 Polymyalgia rheumatica
0.000 0.169 0.831
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.170 0.830
E06.3 Autoimmune thyroiditis
0.000 0.170 0.829
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.171 0.829
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.172 0.828
B34.9 Viral infection, unspecified
0.000 0.175 0.825
E20-E35 Disorders of other endocrine glands
0.000 0.178 0.822
Chapter V Mental and behavioural disorders
0.000 0.183 0.817
M05 Seropositive rheumatoid arthritis
0.000 0.185 0.815
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.188 0.812
D80-D89 Certain disorders involving the immune mechanism
0.000 0.189 0.811
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.193 0.807
M95.0 Acquired deformity of nose
0.000 0.194 0.806
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.203 0.797
M06.0 Seronegative rheumatoid arthritis
0.000 0.203 0.797
L29 Pruritus
0.000 0.204 0.796
E27 Other disorders of adrenal gland
0.000 0.208 0.792
E10.9 Without complications
0.000 0.212 0.788
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.218 0.782
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.220 0.780
L08 Other local infections of skin and subcutaneous tissue
0.000 0.221 0.779
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.222 0.778
H65 Nonsuppurative otitis media
0.000 0.226 0.774
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.228 0.772
H80-H83 Diseases of inner ear
0.000 0.230 0.770
E10.3 With ophthalmic complications
0.000 0.234 0.766
E27.1 Primary adrenocortical insufficiency
0.000 0.234 0.766
B35 Dermatophytosis
0.000 0.239 0.761
B99-B99 Other infectious diseases
0.000 0.244 0.756
D55-D59 Haemolytic anaemias
0.000 0.245 0.755
Chapter IX Diseases of the circulatory system
0.000 0.247 0.753
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.251 0.749
M00-M03 Infectious arthropathies
0.000 0.253 0.747
E66.0 Obesity due to excess calories
0.000 0.255 0.745
E89.0 Postprocedural hypothyroidism
0.000 0.256 0.744
D86 Sarcoidosis
0.000 0.256 0.744
L29.0 Pruritus ani
0.000 0.257 0.743
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.259 0.741
D68.5 Primary Thrombophilia
0.000 0.259 0.741
L05 Pilonidal cyst
0.000 0.260 0.740
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.263 0.737
M35.0 Sicca syndrome [Sjogren]
0.000 0.264 0.736
Chapter XXII Codes for special purposes
0.000 0.267 0.733
E86 Volume depletion
0.000 0.267 0.733
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.268 0.732
D68.9 Coagulation defect, unspecified
0.000 0.269 0.731
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.269 0.731
E88 Other metabolic disorders
0.000 0.276 0.724
L30 Other dermatitis
0.000 0.277 0.723
E73 Lactose intolerance
0.000 0.281 0.719
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.285 0.715
L44 Other papulosquamous disorders
0.000 0.285 0.715
L41 Parapsoriasis
0.000 0.285 0.715
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.285 0.715
L40.8 Other psoriasis
0.000 0.286 0.714
L40.4 Guttate psoriasis
0.000 0.286 0.714
L40.3 Pustulosis palmaris et plantaris
0.000 0.286 0.714
L40.2 Acrodermatitis continua
0.000 0.286 0.714
L40.1 Generalised pustular psoriasis
0.000 0.286 0.714
E50-E64 Other nutritional deficiencies
0.000 0.286 0.714
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.286 0.714
L58 Radiodermatitis
0.000 0.286 0.714
L55 Sunburn
0.000 0.286 0.714
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.288 0.711
L57.5 Actinic granuloma
0.000 0.288 0.711
L57.3 Poikiloderma of Civatte
0.000 0.288 0.711
L57.2 Cutis rhomboidalis nuchae
0.000 0.288 0.711
L57.1 Actinic reticuloid
0.000 0.288 0.711
E67 Other hyperalimentation
0.000 0.290 0.710
E68 Sequelae of hyperalimentation
0.000 0.290 0.710
M34 Systemic sclerosis
0.000 0.291 0.709
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.292 0.708
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.293 0.706
M06.8 Other specified rheumatoid arthritis
0.000 0.295 0.705
M06.2 Rheumatoid bursitis
0.000 0.295 0.705
M06.1 Adult-onset Still's disease
0.000 0.295 0.705
M12 Other specific arthropathies
0.000 0.295 0.705
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.295 0.705
M08 Juvenile arthritis
0.000 0.295 0.705
E66.1 Drug-induced obesity
0.000 0.295 0.705
D50.1 Sideropenic dysphagia
0.000 0.296 0.704
E10.1 With ketoacidosis
0.000 0.297 0.703
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.297 0.703
M14 Arthropathies in other diseases classified elsewhere
0.000 0.300 0.700
L27 Dermatitis due to substances taken internally
0.000 0.301 0.699
L04 Acute lymphadenitis
0.000 0.305 0.695
L01 Impetigo
0.000 0.305 0.695
L00 Staphylococcal scalded skin syndrome
0.000 0.305 0.695
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.305 0.695
B34.8 Other viral infections of unspecified site
0.000 0.307 0.693
I60-I69 Cerebrovascular diseases
0.000 0.307 0.693
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.308 0.692
A75-A79 Rickettsioses
0.000 0.308 0.692
A70-A74 Other diseases caused by chlamydiae
0.000 0.308 0.692
A65-A69 Other spirochaetal diseases
0.000 0.308 0.692
A20-A28 Certain zoonotic bacterial diseases
0.000 0.308 0.692
E65 Localised adiposity
0.000 0.308 0.692
H72.0 Central perforation of tympanic membrane
0.000 0.309 0.691
E10.2 With renal complications
0.000 0.311 0.689
B48 Other mycoses, not elsewhere classified
0.000 0.312 0.688
B47 Mycetoma
0.000 0.312 0.688
B46 Zygomycosis
0.000 0.312 0.688
B45 Cryptococcosis
0.000 0.312 0.688
B43 Chromomycosis and phaeomycotic abscess
0.000 0.312 0.688
B42 Sporotrichosis
0.000 0.312 0.688
B41 Paracoccidioidomycosis
0.000 0.312 0.688
B40 Blastomycosis
0.000 0.312 0.688
B39 Histoplasmosis
0.000 0.312 0.688
B38 Coccidioidomycosis
0.000 0.312 0.688
B36 Other superficial mycoses
0.000 0.312 0.688
B37.7 Candidal septicaemia
0.000 0.313 0.687
B37.6 Candidal endocarditis
0.000 0.313 0.687
B37.5 Candidal meningitis
0.000 0.313 0.687
B25 Cytomegaloviral disease
0.000 0.314 0.686
F40-F48 Neurotic, stress-related and somatoform disorders
0.000 0.314 0.686
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.316 0.684
E06.9 Thyroiditis, unspecified
0.000 0.316 0.684
L57.4 Cutis laxa senilis
0.000 0.317 0.683
M35.7 Hypermobility syndrome
0.000 0.317 0.683
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.322 0.678
L10-L14 Bullous disorders
0.000 0.323 0.677
H80 Otosclerosis
0.000 0.323 0.677
B24 Unspecified human immunodeficiency virus [HIV] disease
0.000 0.324 0.676
D86.9 Sarcoidosis, unspecified
0.000 0.324 0.676
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.324 0.676
A15-A19 Tuberculosis
0.000 0.326 0.674
E74 Other disorders of carbohydrate metabolism
0.000 0.326 0.673
H65.9 Nonsuppurative otitis media, unspecified
0.000 0.327 0.673
D68.0 Von Willebrand's disease
0.000 0.327 0.673
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.329 0.671
F30-F39 Mood [affective] disorders
0.000 0.330 0.670
I05-I09 Chronic rheumatic heart diseases
0.000 0.331 0.669
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.331 0.669
I20-I25 Ischaemic heart diseases
0.000 0.332 0.668
E40-E46 Malnutrition
0.000 0.333 0.667
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.334 0.666
E10.5 With peripheral circulatory complications
0.000 0.336 0.664
E84 Cystic fibrosis
0.000 0.336 0.664
E79 Disorders of purine and pyrimidine metabolism
0.000 0.336 0.664
E77 Disorders of glycoprotein metabolism
0.000 0.336 0.664
E76 Disorders of glycosaminoglycan metabolism
0.000 0.336 0.664
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.336 0.664
E72 Other disorders of amino-acid metabolism
0.000 0.336 0.664
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.336 0.664
E70 Disorders of aromatic amino-acid metabolism
0.000 0.336 0.664
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.336 0.664
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.336 0.663
B50-B64 Protozoal diseases
0.000 0.339 0.661
M46 Other inflammatory spondylopathies
0.000 0.340 0.660
F60-F69 Disorders of adult personality and behaviour
0.000 0.343 0.657
E03.8 Other specified hypothyroidism
0.000 0.345 0.655
I21 Acute myocardial infarction
0.000 0.345 0.655
M11 Other crystal arthropathies
0.000 0.346 0.654
B33 Other viral diseases, not elsewhere classified
0.000 0.347 0.653
B30 Viral conjunctivitis
0.000 0.347 0.653
B27 Infectious mononucleosis
0.000 0.347 0.653
B26 Mumps
0.000 0.347 0.653
E14 Unspecified diabetes mellitus
0.000 0.347 0.653
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.347 0.653
D66 Hereditary factor VIII deficiency
0.000 0.347 0.652
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.348 0.652
D67 Hereditary factor IX deficiency
0.000 0.349 0.651
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.349 0.651
E06.5 Other chronic thyroiditis
0.000 0.350 0.650
E06.4 Drug-induced thyroiditis
0.000 0.350 0.650
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.350 0.650
E06.1 Subacute thyroiditis
0.000 0.350 0.650
E06.0 Acute thyroiditis
0.000 0.350 0.650
M07.6 Other enteropathic arthropathies
0.000 0.350 0.650
M07.5 Arthropathy in ulcerative colitis
0.000 0.350 0.650
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.350 0.650
M07.2 Psoriatic spondylitis
0.000 0.350 0.650
M07.1 Arthritis mutilans
0.000 0.350 0.650
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.350 0.650
D68.2 Hereditary deficiency of other clotting factors
0.000 0.350 0.650
M91-M94 Chondropathies
0.000 0.351 0.649
F80-F89 Disorders of psychological development
0.000 0.351 0.649
L28 Lichen simplex chronicus and prurigo
0.000 0.351 0.649
E22 Hyperfunction of pituitary gland
0.000 0.352 0.648
E10.4 With neurological complications
0.000 0.354 0.646
D52 Folate deficiency anaemia
0.000 0.354 0.646
L24 Irritant contact dermatitis
0.000 0.355 0.645
L21 Seborrhoeic dermatitis
0.000 0.355 0.645
L26 Exfoliative dermatitis
0.000 0.355 0.645
L22 Diaper [napkin] dermatitis
0.000 0.355 0.645
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.355 0.645
I69 Sequelae of cerebrovascular disease
0.000 0.355 0.645
M06.3 Rheumatoid nodule
0.000 0.356 0.644
E05.9 Thyrotoxicosis, unspecified
0.000 0.357 0.643
L05.0 Pilonidal cyst with abscess
0.000 0.358 0.642
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.359 0.641
H60-H62 Diseases of external ear
0.000 0.360 0.640
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.360 0.640
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.360 0.640
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.360 0.640
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.360 0.640
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.360 0.640
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.360 0.640
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.360 0.640
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.360 0.640
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.360 0.640
H73 Other disorders of tympanic membrane
0.000 0.361 0.639
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.362 0.638
E87.2 Acidosis
0.000 0.362 0.638
L20 Atopic dermatitis
0.000 0.362 0.637
E12 Malnutrition-related diabetes mellitus
0.000 0.365 0.635
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.365 0.634
B37.9 Candidiasis, unspecified
0.000 0.366 0.634
D86.0 Sarcoidosis of lung
0.000 0.367 0.633
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.367 0.633
M99 Biomechanical lesions, not elsewhere classified
0.000 0.368 0.632
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.368 0.632
M49 Spondylopathies in diseases classified elsewhere
0.000 0.370 0.630
B37.1 Pulmonary candidiasis
0.000 0.370 0.630
D51 Vitamin B12 deficiency anaemia
0.000 0.370 0.630
E07 Other disorders of thyroid
0.000 0.373 0.627
L25 Unspecified contact dermatitis
0.000 0.373 0.627
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.373 0.627
B37.2 Candidiasis of skin and nail
0.000 0.374 0.626
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.374 0.626
B37.4 Candidiasis of other urogenital sites
0.000 0.374 0.625
I73 Other peripheral vascular diseases
0.000 0.375 0.625
B65-B83 Helminthiases
0.000 0.376 0.624
B15-B19 Viral hepatitis
0.000 0.377 0.623
I21.9 Acute myocardial infarction, unspecified
0.000 0.378 0.622
B34.3 Parvovirus infection, unspecified
0.000 0.379 0.621
B34.2 Coronavirus infection, unspecified
0.000 0.379 0.621
B34.1 Enterovirus infection, unspecified
0.000 0.379 0.621
B34.0 Adenovirus infection, unspecified
0.000 0.379 0.621
M60-M63 Disorders of muscles
0.000 0.380 0.620
E85 Amyloidosis
0.000 0.380 0.620
E10.7 With multiple complications
0.000 0.381 0.619
I77 Other disorders of arteries and arterioles
0.000 0.381 0.619
D69 Purpura and other haemorrhagic conditions
0.000 0.381 0.619
L29.9 Pruritus, unspecified
0.000 0.382 0.617
E10.0 With coma
0.000 0.384 0.616
M06.4 Inflammatory polyarthropathy
0.000 0.385 0.615
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.385 0.615
H68 Eustachian salpingitis and obstruction
0.000 0.385 0.615
H67 Otitis media in diseases classified elsewhere
0.000 0.385 0.615
I08 Multiple valve diseases
0.000 0.387 0.613
M22 Disorders of patella
0.000 0.387 0.613
D59 Acquired haemolytic anaemia
0.000 0.387 0.613
F31 Bipolar affective disorder
0.000 0.388 0.612
D68.4 Acquired coagulation factor deficiency
0.000 0.388 0.612
D68.1 Hereditary factor XI deficiency
0.000 0.388 0.612
H70 Mastoiditis and related conditions
0.000 0.389 0.611
D53 Other nutritional anaemias
0.000 0.389 0.611
E05.5 Thyroid crisis or storm
0.000 0.389 0.611
E05.4 Thyrotoxicosis factitia
0.000 0.389 0.611
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.389 0.611
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.389 0.611
M07.38 Other psoriatic arthropathies (Other)
0.000 0.390 0.610
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.390 0.610
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.390 0.610
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.390 0.610
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.390 0.610
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.390 0.610
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.390 0.610
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.390 0.610
H80.9 Otosclerosis, unspecified
0.000 0.390 0.610
M80-M85 Disorders of bone density and structure
0.001 0.390 0.608
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.391 0.609
L23 Allergic contact dermatitis
0.000 0.392 0.608
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.394 0.606
B99 Other and unspecified infectious diseases
0.000 0.394 0.606
F42 Obsessive-compulsive disorder
0.000 0.394 0.606
H65.2 Chronic serous otitis media
0.000 0.394 0.606
B35.1 Tinea unguium
0.000 0.397 0.603
H72.1 Attic perforation of tympanic membrane
0.000 0.397 0.602
F00-F09 Organic, including symptomatic, mental disorders
0.000 0.397 0.603
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.398 0.602
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.398 0.602
I67 Other cerebrovascular diseases
0.000 0.398 0.602
B34.4 Papovirus infection, unspecified
0.000 0.399 0.601
M30 Polyarteritis nodosa and related conditions
0.000 0.399 0.601
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.000 0.400 0.600
M95.8 Other specified acquired deformities of musculoskeletal system
0.000 0.400 0.600
M95.5 Acquired deformity of pelvis
0.000 0.400 0.600
M95.4 Acquired deformity of chest and rib
0.000 0.400 0.600
M95.3 Acquired deformity of neck
0.000 0.400 0.600
M95.2 Other acquired deformity of head
0.000 0.400 0.600
M95.1 Cauliflower ear
0.000 0.400 0.600
H83 Other diseases of inner ear
0.000 0.401 0.599
I69.3 Sequelae of cerebral infarction
0.000 0.402 0.598
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.402 0.598
M35.8 Other specified systemic involvement of connective tissue
0.000 0.402 0.598
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.402 0.598
M35.5 Multifocal fibrosclerosis
0.000 0.402 0.598
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.402 0.598
M35.2 Behcet's disease
0.000 0.402 0.598
M35.1 Other overlap syndromes
0.000 0.402 0.598
H65.4 Other chronic nonsuppurative otitis media
0.000 0.403 0.597
M34.9 Systemic sclerosis, unspecified
0.000 0.404 0.596
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.404 0.596
M32 Systemic lupus erythematosus
0.000 0.404 0.596
I73.0 Raynaud's syndrome
0.000 0.405 0.595
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.406 0.594
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.407 0.593
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.410 0.590
E32 Diseases of thymus
0.000 0.410 0.590
E31 Polyglandular dysfunction
0.000 0.410 0.590
E30 Disorders of puberty, not elsewhere classified
0.000 0.410 0.590
E25 Adrenogenital disorders
0.000 0.410 0.590
E20 Hypoparathyroidism
0.000 0.410 0.590
L43 Lichen planus
0.000 0.410 0.590
L42 Pityriasis rosea
0.000 0.410 0.589
I63 Cerebral infarction
0.000 0.411 0.589
L30.8 Other specified dermatitis
0.000 0.413 0.587
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.413 0.587
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.414 0.586
M05.8 Other seropositive rheumatoid arthritis
0.000 0.415 0.584
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.415 0.584
M05.2 Rheumatoid vasculitis
0.000 0.415 0.584
M05.1 Rheumatoid lung disease
0.000 0.415 0.584
M05.0 Felty's syndrome
0.000 0.415 0.584
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.418 0.582
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.418 0.582
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.418 0.582
E89.5 Postprocedural testicular hypofunction
0.000 0.418 0.582
E89.4 Postprocedural ovarian failure
0.000 0.418 0.582
E89.1 Postprocedural hypoinsulinaemia
0.000 0.418 0.582
D84 Other immunodeficiencies
0.000 0.418 0.582
D83 Common variable immunodeficiency
0.000 0.418 0.582
D82 Immunodeficiency associated with other major defects
0.000 0.418 0.582
D81 Combined immunodeficiencies
0.000 0.418 0.582
E10.8 With unspecified complications
0.000 0.419 0.581
E83 Disorders of mineral metabolism
0.000 0.420 0.580
M00 Pyogenic arthritis
0.000 0.422 0.578
D68.6 Other Thrombophilia
0.000 0.422 0.578
F70-F79 Mental retardation
0.000 0.425 0.575
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.428 0.572
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.000 0.428 0.572
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions
0.000 0.428 0.571
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases
0.000 0.428 0.571
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms
0.000 0.428 0.571
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
0.000 0.428 0.571
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.428 0.571
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.428 0.571
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.428 0.571
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.428 0.571
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.428 0.571
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.428 0.571
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.428 0.571
E73.9 Lactose intolerance, unspecified
0.000 0.429 0.571
L29.8 Other pruritus
0.000 0.429 0.570
L29.3 Anogenital pruritus, unspecified
0.000 0.429 0.570
L29.1 Pruritus scroti
0.000 0.429 0.570
E26 Hyperaldosteronism
0.000 0.431 0.569
E27.5 Adrenomedullary hyperfunction
0.000 0.432 0.568
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.432 0.568
E27.2 Addisonian crisis
0.000 0.432 0.568
E27.0 Other adrenocortical overactivity
0.000 0.432 0.568
B35.3 Tinea pedis
0.000 0.432 0.568
F43 Reaction to severe stress, and adjustment disorders
0.000 0.432 0.568
I67.8 Other specified cerebrovascular diseases
0.000 0.433 0.567
M80 Osteoporosis with pathological fracture
0.000 0.433 0.566
L40.0 Psoriasis vulgaris
0.000 0.435 0.565
E89.3 Postprocedural hypopituitarism
0.000 0.435 0.565
H65.3 Chronic mucoid otitis media
0.000 0.436 0.564
A80-A89 Viral infections of the central nervous system
0.000 0.439 0.560
I77.1 Stricture of artery
0.000 0.439 0.561
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.440 0.560
B37.3 Candidiasis of vulva and vagina
0.000 0.440 0.560
E87.4 Mixed disorder of acid-base balance
0.000 0.441 0.559
M13 Other arthritis
0.000 0.441 0.559
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.441 0.558
L08.1 Erythrasma
0.000 0.442 0.558
L08.0 Pyoderma
0.000 0.442 0.558
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.442 0.558
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.442 0.558
I62 Other nontraumatic intracranial haemorrhage
0.000 0.443 0.557
F40 Phobic anxiety disorders
0.000 0.443 0.557
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.000 0.444 0.556
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.445 0.555
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.445 0.555
H65.1 Other acute nonsuppurative otitis media
0.000 0.445 0.555
H65.0 Acute serous otitis media
0.000 0.445 0.555
M33 Dermatopolymyositis
0.000 0.445 0.554
M34.1 CR(E)ST syndrome
0.000 0.446 0.554
E89.2 Postprocedural hypoparathyroidism
0.000 0.447 0.553
H69 Other disorders of Eustachian tube
0.000 0.447 0.553
E87.5 Hyperkalaemia
0.000 0.447 0.553
I05 Rheumatic mitral valve diseases
0.000 0.448 0.552
E10.6 With other specified complications
0.000 0.448 0.552
H82 Vertiginous syndromes in diseases classified elsewhere
0.000 0.448 0.552
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.450 0.550
I22 Subsequent myocardial infarction
0.000 0.451 0.549
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.451 0.549
F42.9 Obsessive-compulsive disorder, unspecified
0.000 0.451 0.549
F81 Specific developmental disorders of scholastic skills
0.000 0.452 0.548
I60 Subarachnoid haemorrhage
0.000 0.453 0.547
F60 Specific personality disorders
0.000 0.453 0.547
B35.9 Dermatophytosis, unspecified
0.000 0.454 0.546
B35.8 Other dermatophytoses
0.000 0.454 0.546
B35.6 Tinea cruris
0.000 0.454 0.546
B35.5 Tinea imbricata
0.000 0.454 0.546
B35.4 Tinea corporis
0.000 0.454 0.546
B35.2 Tinea manuum
0.000 0.454 0.546
B35.0 Tinea barbae and tinea capitis
0.000 0.454 0.546
E14.9 Without complications
0.000 0.455 0.545
E34 Other endocrine disorders
0.000 0.456 0.544
M10 Gout
0.000 0.456 0.543
E80.4 Gilbert's syndrome
0.000 0.458 0.542
F99-F99 Unspecified mental disorder
0.000 0.458 0.542
D57 Sickle-cell disorders
0.000 0.458 0.541
D56 Thalassaemia
0.000 0.458 0.541
D55 Anaemia due to enzyme disorders
0.000 0.458 0.541
E87.6 Hypokalaemia
0.000 0.459 0.541
E27.9 Disorder of adrenal gland, unspecified
0.000 0.459 0.541
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.459 0.540
I00-I02 Acute rheumatic fever
0.000 0.460 0.540
E53 Deficiency of other B group vitamins
0.000 0.460 0.540
B49 Unspecified mycosis
0.000 0.460 0.539
L50-L54 Urticaria and erythema
0.000 0.461 0.539
I77.6 Arteritis, unspecified
0.000 0.461 0.538
E66.9 Obesity, unspecified
0.000 0.463 0.537
E87.7 Fluid overload
0.000 0.463 0.537
I70 Atherosclerosis
0.000 0.464 0.536
I67.2 Cerebral atherosclerosis
0.000 0.464 0.536
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.000 0.465 0.535
M02 Reactive arthropathies
0.000 0.465 0.535
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.000 0.465 0.535
E22.0 Acromegaly and pituitary gigantism
0.000 0.465 0.535
E27.8 Other specified disorders of adrenal gland
0.000 0.465 0.535
D68.8 Other specified coagulation defects
0.000 0.466 0.534
D86.3 Sarcoidosis of skin
0.000 0.466 0.534
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.466 0.534
D86.1 Sarcoidosis of lymph nodes
0.000 0.466 0.534
D50.8 Other iron deficiency anaemias
0.000 0.467 0.533
F45 Somatoform disorders
0.000 0.467 0.532
L30.9 Dermatitis, unspecified
0.000 0.468 0.532
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.469 0.531
L56.4 Polymorphous light eruption
0.000 0.469 0.531

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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