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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2523502
log Bayes Factor = 64.9853
Chromosome 6   position 31,513,864  (GRCh37) Explore rs2523502 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.001 0.999
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.002 0.998
E78.0 Pure hypercholesterolaemia
0.000 0.003 0.997
I20 Angina pectoris
0.000 0.007 0.993
E14.3 With ophthalmic complications
0.000 0.011 0.989
I25.5 Ischaemic cardiomyopathy
0.000 0.011 0.989
I22 Subsequent myocardial infarction
0.000 0.012 0.988
E10.1 With ketoacidosis
0.000 0.014 0.986
E83.1 Disorders of iron metabolism
0.984 0.016 0.000
E14.9 Without complications
0.000 0.021 0.979
E10.4 With neurological complications
0.000 0.022 0.978
I20.9 Angina pectoris, unspecified
0.000 0.022 0.978
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.028 0.972
G35-G37 Demyelinating diseases of the central nervous system
0.969 0.031 0.000
I20.0 Unstable angina
0.000 0.032 0.968
I21 Acute myocardial infarction
0.000 0.032 0.968
G37 Other demyelinating diseases of central nervous system
0.963 0.037 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.038 0.962
I25.2 Old myocardial infarction
0.000 0.038 0.962
I10 Essential (primary) hypertension
0.000 0.052 0.948
G37.9 Demyelinating disease of central nervous system, unspecified
0.946 0.054 0.000
I21.9 Acute myocardial infarction, unspecified
0.000 0.067 0.933
E13 Other specified diabetes mellitus
0.000 0.068 0.932
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.073 0.927
E70-E90 Metabolic disorders
0.000 0.079 0.920
I24 Other acute ischaemic heart diseases
0.000 0.080 0.920
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.085 0.915
E78.8 Other disorders of lipoprotein metabolism
0.000 0.095 0.905
L40-L45 Papulosquamous disorders
0.000 0.095 0.904
E10.2 With renal complications
0.000 0.112 0.888
I10-I15 Hypertensive diseases
0.000 0.115 0.885
L43 Lichen planus
0.000 0.116 0.884
E13.9 Without complications
0.000 0.116 0.884
R07.4 Chest pain, unspecified
0.000 0.127 0.873
E11.0 With coma
0.000 0.129 0.871
I21.4 Acute subendocardial myocardial infarction
0.000 0.132 0.868
L43.9 Lichen planus, unspecified
0.000 0.143 0.857
I25.3 Aneurysm of heart
0.000 0.143 0.857
G37.8 Other specified demyelinating diseases of central nervous system
0.849 0.151 0.000
L40.8 Other psoriasis
0.000 0.156 0.844
E11.1 With ketoacidosis
0.000 0.156 0.844
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.157 0.843
E11.2 With renal complications
0.000 0.171 0.829
E14.4 With neurological complications
0.000 0.174 0.826
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.176 0.824
E10.8 With unspecified complications
0.000 0.176 0.824
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.178 0.822
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.180 0.820
E78.2 Mixed hyperlipidaemia
0.000 0.185 0.815
E10.0 With coma
0.000 0.188 0.812
E00-E07 Disorders of thyroid gland
0.000 0.196 0.804
I24.8 Other forms of acute ischaemic heart disease
0.000 0.215 0.785
I15 Secondary hypertension
0.000 0.215 0.785
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.785 0.215 0.000
E03 Other hypothyroidism
0.000 0.222 0.778
E10.5 With peripheral circulatory complications
0.000 0.225 0.775
E03.9 Hypothyroidism, unspecified
0.000 0.230 0.770
E85 Amyloidosis
0.000 0.231 0.768
I12 Hypertensive renal disease
0.000 0.241 0.759
L40.0 Psoriasis vulgaris
0.000 0.242 0.758
E11.6 With other specified complications
0.000 0.246 0.754
L43.8 Other lichen planus
0.000 0.247 0.753
E16 Other disorders of pancreatic internal secretion
0.000 0.250 0.750
E78.6 Lipoprotein deficiency
0.000 0.259 0.741
E10.6 With other specified complications
0.000 0.262 0.738
I23 Certain current complications following acute myocardial infarction
0.000 0.263 0.737
E14.5 With peripheral circulatory complications
0.000 0.264 0.736
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.273 0.727
E14.6 With other specified complications
0.000 0.276 0.724
E74 Other disorders of carbohydrate metabolism
0.000 0.277 0.722
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
I15.1 Hypertension secondary to other renal disorders
0.000 0.284 0.716
E78.1 Pure hyperglyceridaemia
0.000 0.285 0.715
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.295 0.705
I11 Hypertensive heart disease
0.000 0.302 0.698
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.303 0.697
E78.3 Hyperchylomicronaemia
0.000 0.303 0.697
G36 Other acute disseminated demyelination
0.697 0.303 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.304 0.696
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.306 0.694
G37.5 Concentric sclerosis [Balo]
0.690 0.310 0.000
G37.4 Subacute necrotising myelitis
0.690 0.310 0.000
G37.2 Central pontine myelinolysis
0.690 0.310 0.000
G37.1 Central demyelination of corpus callosum
0.690 0.310 0.000
G37.0 Diffuse sclerosis
0.690 0.310 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.315 0.685
E11.5 With peripheral circulatory complications
0.000 0.320 0.680
I12.9 Hypertensive renal disease without renal failure
0.000 0.322 0.678
I22.8 Subsequent myocardial infarction of other sites
0.000 0.327 0.673
E78.4 Other hyperlipidaemia
0.000 0.330 0.670
E13.8 With unspecified complications
0.000 0.331 0.668
E13.7 With multiple complications
0.000 0.331 0.668
E13.6 With other specified complications
0.000 0.331 0.668
E13.5 With peripheral circulatory complications
0.000 0.331 0.668
E13.4 With neurological complications
0.000 0.331 0.668
E13.3 With ophthalmic complications
0.000 0.331 0.668
E13.2 With renal complications
0.000 0.331 0.668
E13.1 With ketoacidosis
0.000 0.331 0.668
E13.0 With coma
0.000 0.331 0.668
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.332 0.668
E79 Disorders of purine and pyrimidine metabolism
0.000 0.338 0.662
L42 Pityriasis rosea
0.000 0.339 0.660
E77 Disorders of glycoprotein metabolism
0.000 0.340 0.660
E76 Disorders of glycosaminoglycan metabolism
0.000 0.340 0.660
E72 Other disorders of amino-acid metabolism
0.000 0.340 0.660
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.340 0.660
E70 Disorders of aromatic amino-acid metabolism
0.000 0.340 0.660
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.340 0.660
E05.9 Thyrotoxicosis, unspecified
0.000 0.342 0.658
E85.9 Amyloidosis, unspecified
0.000 0.345 0.655
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.347 0.652
L44 Other papulosquamous disorders
0.000 0.351 0.648
L41 Parapsoriasis
0.000 0.351 0.648
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.351 0.648
I13 Hypertensive heart and renal disease
0.000 0.366 0.634
L43.3 Subacute (active) lichen planus
0.000 0.366 0.634
L43.2 Lichenoid drug reaction
0.000 0.366 0.634
L43.1 Bullous lichen planus
0.000 0.366 0.634
L43.0 Hypertrophic lichen planus
0.000 0.366 0.634
I20.1 Angina pectoris with documented spasm
0.000 0.369 0.631
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.370 0.630
E84 Cystic fibrosis
0.001 0.394 0.605
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.405 0.595
E16.1 Other hypoglycaemia
0.000 0.407 0.593
E40-E46 Malnutrition
0.000 0.409 0.591
E15 Nondiabetic hypoglycaemic coma
0.000 0.409 0.591
E78.5 Hyperlipidaemia, unspecified
0.000 0.411 0.589
I25.4 Coronary artery aneurysm
0.000 0.411 0.588
Chapter IX Diseases of the circulatory system
0.000 0.418 0.582
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.419 0.580
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.424 0.576
E00 Congenital iodine-deficiency syndrome
0.000 0.424 0.576
E85.4 Organ-limited amyloidosis
0.000 0.432 0.567
E11.3 With ophthalmic complications
0.000 0.435 0.565
I15.8 Other secondary hypertension
0.000 0.437 0.563
I15.2 Hypertension secondary to endocrine disorders
0.000 0.437 0.563
I15.0 Renovascular hypertension
0.000 0.437 0.563
E89.3 Postprocedural hypopituitarism
0.000 0.437 0.563
E03.5 Myxoedema coma
0.000 0.442 0.558
E03.4 Atrophy of thyroid (acquired)
0.000 0.442 0.558
E03.3 Postinfectious hypothyroidism
0.000 0.442 0.558
E03.1 Congenital hypothyroidism without goitre
0.000 0.442 0.558
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.442 0.558
I15.9 Seconday hypertension, unspecified
0.000 0.445 0.555
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.446 0.554
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.448 0.552
E83 Disorders of mineral metabolism
0.467 0.448 0.084
E85.8 Other amyloidosis
0.000 0.449 0.551
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.449 0.551
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.449 0.551
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.449 0.551
I23.8 Other current complications following acute myocardial infarction
0.000 0.451 0.549
E85.3 Secondary systemic amyloidosis
0.000 0.458 0.542
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.462 0.538
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.462 0.538
E16.4 Abnormal secretion of gastrin
0.000 0.462 0.538
E16.3 Increased secretion of glucagon
0.000 0.462 0.538
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.471 0.528
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.471 0.528
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.471 0.528
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.471 0.528
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.471 0.528
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.471 0.528
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.471 0.528
I24.1 Dressler's syndrome
0.000 0.472 0.528
I12.0 Hypertensive renal disease with renal failure
0.000 0.480 0.520
E07 Other disorders of thyroid
0.000 0.481 0.519
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.482 0.518
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.482 0.518
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.482 0.518
E74.2 Disorders of galactose metabolism
0.000 0.482 0.518
E74.1 Disorders of fructose metabolism
0.000 0.482 0.518
E74.0 Glycogen storage disease
0.000 0.482 0.518
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.484 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E05.5 Thyroid crisis or storm
0.000 0.494 0.506
E05.4 Thyrotoxicosis factitia
0.000 0.494 0.506
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.494 0.506
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.494 0.506
E11.4 With neurological complications
0.000 0.497 0.503
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.497 0.502
G36.0 Neuromyelitis optica [Devic]
0.501 0.498 0.000
G36.9 Acute disseminated demyelination, unspecified
0.499 0.500 0.000
G36.8 Other specified acute disseminated demyelination
0.499 0.500 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.499 0.500 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.500 0.499
E73 Lactose intolerance
0.001 0.502 0.498
E11.8 With unspecified complications
0.000 0.502 0.497
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.505 0.494
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.523 0.477
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.525 0.475
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.525 0.475
E79.1 Lesch-Nyhan syndrome
0.000 0.525 0.475
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.527 0.473
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.527 0.473
E70.3 Albinism
0.000 0.527 0.473
E70.2 Disorders of tyrosine metabolism
0.000 0.527 0.473
E70.1 Other hyperphenylalaninaemias
0.000 0.527 0.473
E70.0 Classical phenylketonuria
0.000 0.527 0.473
E71.3 Disorders of fatty-acid metabolism
0.000 0.527 0.473
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.527 0.473
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.527 0.473
E71.0 Maple-syrup-urine disease
0.000 0.527 0.473
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.527 0.473
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.527 0.473
E72.5 Disorders of glycine metabolism
0.000 0.527 0.473
E72.4 Disorders of ornithine metabolism
0.000 0.527 0.473
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.527 0.473
E72.2 Disorders of urea cycle metabolism
0.000 0.527 0.473
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.527 0.473
E72.0 Disorders of amino-acid transport
0.000 0.527 0.473
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.527 0.473
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.527 0.473
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.527 0.473
E76.2 Other mucopolysaccharidoses
0.000 0.527 0.473
E76.1 Mucopolysaccharidosis, type II
0.000 0.527 0.473
E76.0 Mucopolysaccharidosis, type I
0.000 0.527 0.473
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.527 0.473
E77.8 Other disorders of glycoprotein metabolism
0.000 0.527 0.473
E77.1 Defects in glycoprotein degradation
0.000 0.527 0.473
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.527 0.473
E06 Thyroiditis
0.000 0.529 0.471
E75.6 Lipid storage disorder, unspecified
0.000 0.532 0.468
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.532 0.468
E75.3 Sphingolipidosis, unspecified
0.000 0.532 0.468
E75.2 Other sphingolipidosis
0.000 0.532 0.468
E75.1 Other gangliosidosis
0.000 0.532 0.468
E75.0 GM2 gangliosidosis
0.000 0.532 0.468
L41.9 Parapsoriasis, unspecified
0.000 0.535 0.465
L41.8 Other parapsoriasis
0.000 0.535 0.465
L41.5 Retiform parapsoriasis
0.000 0.535 0.465
L41.4 Large plaque parapsoriasis
0.000 0.535 0.465
L41.3 Small plaque parapsoriasis
0.000 0.535 0.465
L41.2 Lymphomatoid papulosis
0.000 0.535 0.465
L41.1 Pityriasis lichenoides chronica
0.000 0.535 0.465
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.535 0.465
L44.9 Papulosquamous disorder, unspecified
0.000 0.535 0.465
L44.8 Other specified papulosquamous disorders
0.000 0.535 0.465
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.535 0.465
L44.3 Lichen ruber moniliformis
0.000 0.535 0.465
L44.2 Lichen striatus
0.000 0.535 0.465
L44.1 Lichen nitidus
0.000 0.535 0.465
L44.0 Pityriasis rubra pilaris
0.000 0.535 0.465
E75.5 Other lipid storage disorders
0.000 0.540 0.460
E88 Other metabolic disorders
0.001 0.541 0.458
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.545 0.455
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.545 0.455
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.545 0.455
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.545 0.455
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.548 0.451
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.548 0.451
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.548 0.451
E89.5 Postprocedural testicular hypofunction
0.000 0.548 0.451
E89.1 Postprocedural hypoinsulinaemia
0.000 0.548 0.451
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.556 0.444
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.556 0.444
E84.8 Cystic fibrosis with other manifestations
0.001 0.565 0.434
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.565 0.434
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.565 0.434
E83.3 Disorders of phosphorus metabolism
0.409 0.566 0.025
E89.4 Postprocedural ovarian failure
0.000 0.574 0.426
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.576 0.424
E45 Retarded development following protein-energy malnutrition
0.000 0.576 0.424
E43 Unspecified severe protein-energy malnutrition
0.000 0.576 0.424
E42 Marasmic kwashiorkor
0.000 0.576 0.424
E41 Nutritional marasmus
0.000 0.576 0.424
E40 Kwashiorkor
0.000 0.576 0.424
E50-E64 Other nutritional deficiencies
0.000 0.578 0.422
K90 Intestinal malabsorption
0.000 0.583 0.417
I00-I02 Acute rheumatic fever
0.000 0.583 0.417
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.587 0.413
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.587 0.413
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.587 0.413
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.587 0.413
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.587 0.413
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.587 0.413
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.587 0.413
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.587 0.413
E65-E68 Obesity and other hyperalimentation
0.000 0.587 0.413
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.589 0.411
E05.8 Other thyrotoxicosis
0.000 0.591 0.409
E89.2 Postprocedural hypoparathyroidism
0.000 0.593 0.407
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.603 0.397
E83.9 Disorder of mineral metabolism, unspecified
0.335 0.604 0.061
E83.8 Other disorders of mineral metabolism
0.335 0.604 0.061
E83.2 Disorders of zinc metabolism
0.335 0.604 0.061
E83.0 Disorders of copper metabolism
0.335 0.604 0.061
E84.9 Cystic fibrosis, unspecified
0.001 0.620 0.380
E80.6 Other disorders of bilirubin metabolism
0.000 0.621 0.378
E07.8 Other specified disorders of thyroid
0.000 0.625 0.374
E07.1 Dyshormogenetic goitre
0.000 0.627 0.372
E07.0 Hypersecretion of calcitonin
0.000 0.627 0.372
E88.2 Lipomatosis, not elsewhere classified
0.000 0.633 0.366
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.639 0.360
E80.5 Crigler-Najjar syndrome
0.000 0.639 0.360
E80.3 Defects of catalase and peroxydase
0.000 0.639 0.360
E80.2 Other porphyria
0.000 0.639 0.360
E80.1 Porphyria cutanea tarda
0.000 0.639 0.360
E80.0 Hereditary erythropoietic porphyria
0.000 0.639 0.360
E73.8 Other lactose intolerance
0.001 0.642 0.357
E73.1 Secondary lactase deficiency
0.001 0.642 0.357
E73.0 Congenital lactase deficiency
0.001 0.642 0.357
E46 Unspecified protein-energy malnutrition
0.000 0.649 0.351
E06.5 Other chronic thyroiditis
0.000 0.662 0.338
E06.4 Drug-induced thyroiditis
0.000 0.662 0.338
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.662 0.338
E06.1 Subacute thyroiditis
0.000 0.662 0.338
E06.0 Acute thyroiditis
0.000 0.662 0.338
E03.8 Other specified hypothyroidism
0.001 0.662 0.337
E88.8 Other specified metabolic disorders
0.001 0.668 0.331
E61 Deficiency of other nutrient elements
0.000 0.669 0.330
E88.9 Metabolic disorder, unspecified
0.001 0.671 0.329
E88.3 Tumour lysis syndrome
0.001 0.673 0.326
E20-E35 Disorders of other endocrine glands
0.000 0.682 0.318
E07.9 Disorder of thyroid, unspecified
0.000 0.687 0.313
E06.9 Thyroiditis, unspecified
0.000 0.689 0.310
E44.1 Mild protein-energy malnutrition
0.000 0.696 0.304
E44.0 Moderate protein-energy malnutrition
0.000 0.696 0.304
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.697 0.303
E63 Other nutritional deficiencies
0.000 0.697 0.303
E56 Other vitamin deficiencies
0.000 0.697 0.303
E51 Thiamine deficiency
0.000 0.697 0.303
E50 Vitamin A deficiency
0.000 0.697 0.303
E60 Dietary zinc deficiency
0.000 0.697 0.303
E59 Dietary selenium deficiency
0.000 0.697 0.303
E58 Dietary calcium deficiency
0.000 0.697 0.303
E54 Ascorbic acid deficiency
0.000 0.697 0.303
E52 Niacin deficiency [pellagra]
0.000 0.697 0.303
K90.8 Other intestinal malabsorption
0.000 0.699 0.301
K90.3 Pancreatic steatorrhoea
0.000 0.701 0.299
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.701 0.299
K90.1 Tropical sprue
0.000 0.701 0.299
I02 Rheumatic chorea
0.000 0.701 0.299
I01 Rheumatic fever with heart involvement
0.000 0.701 0.299
I00 Rheumatic fever without mention of heart involvement
0.000 0.701 0.299
K90.9 Intestinal malabsorption, unspecified
0.000 0.701 0.299
E67 Other hyperalimentation
0.000 0.704 0.296
E68 Sequelae of hyperalimentation
0.000 0.704 0.296
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.714 0.286
E65 Localised adiposity
0.000 0.724 0.276
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.724 0.276
E06.3 Autoimmune thyroiditis
0.000 0.726 0.274
E61.1 Iron deficiency
0.000 0.730 0.270
E23 Hypofunction and other disorders of pituitary gland
0.000 0.731 0.269
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.739 0.260
E22 Hyperfunction of pituitary gland
0.000 0.750 0.250
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.751 0.248
E89.0 Postprocedural hypothyroidism
0.000 0.756 0.244
E83.4 Disorders of magnesium metabolism
0.191 0.763 0.046
E61.9 Deficiency of nutrient element, unspecified
0.000 0.763 0.237
E61.8 Deficiency of other specified nutrient elements
0.000 0.763 0.237
E61.7 Deficiency of multiple nutrient elements
0.000 0.763 0.237
E61.6 Vanadium deficiency
0.000 0.763 0.237
E61.5 Molybdenum deficiency
0.000 0.763 0.237
E61.4 Chromium deficiency
0.000 0.763 0.237
E61.3 Manganese deficiency
0.000 0.763 0.237
E61.0 Copper deficiency
0.000 0.763 0.237
E55 Vitamin D deficiency
0.000 0.771 0.229
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.771 0.228
E32 Diseases of thymus
0.000 0.771 0.228
E31 Polyglandular dysfunction
0.000 0.771 0.228
E30 Disorders of puberty, not elsewhere classified
0.000 0.771 0.228
E25 Adrenogenital disorders
0.000 0.771 0.228
E61.2 Magnesium deficiency
0.000 0.772 0.228
E23.6 Other disorders of pituitary gland
0.000 0.773 0.227
E26 Hyperaldosteronism
0.000 0.774 0.226
E23.2 Diabetes insipidus
0.000 0.777 0.223
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.778 0.222
E50.9 Vitamin A deficiency, unspecified
0.000 0.783 0.217
E50.8 Other manifestations of vitamin A deficiency
0.000 0.783 0.217
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.783 0.217
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.783 0.217
E50.5 Vitamin A deficiency with night blindness
0.000 0.783 0.217
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.783 0.217
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.783 0.217
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.783 0.217
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.783 0.217
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.783 0.217
E51.9 Thiamine deficiency, unspecified
0.000 0.783 0.217
E51.8 Other manifestations of thiamine deficiency
0.000 0.783 0.217
E51.2 Wernicke's encephalopathy
0.000 0.783 0.217
E51.1 Beriberi
0.000 0.783 0.217
E56.9 Vitamin deficiency, unspecified
0.000 0.783 0.217
E56.8 Deficiency of other vitamins
0.000 0.783 0.217
E56.1 Deficiency of vitamin K
0.000 0.783 0.217
E56.0 Deficiency of vitamin E
0.000 0.783 0.217
E63.9 Nutritional deficiency, unspecified
0.000 0.783 0.217
E63.8 Other specified nutritional deficiencies
0.000 0.783 0.217
E63.1 Imbalance of constituents of food intake
0.000 0.783 0.217
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.783 0.217
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.783 0.217
E64.8 Sequelae of other nutritional deficiencies
0.000 0.783 0.217
E64.3 Sequelae of rickets
0.000 0.783 0.217
E64.2 Sequelae of vitamin C deficiency
0.000 0.783 0.217
E64.1 Sequelae of vitamin A deficiency
0.000 0.783 0.217
E64.0 Sequelae of protein-energy malnutrition
0.000 0.783 0.217
E24 Cushing's syndrome
0.000 0.784 0.215
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.785 0.214
I01.8 Other acute rheumatic heart disease
0.000 0.785 0.214
I01.2 Acute rheumatic myocarditis
0.000 0.785 0.214
I01.1 Acute rheumatic endocarditis
0.000 0.785 0.214
I01.0 Acute rheumatic pericarditis
0.000 0.785 0.214
I02.9 Rheumatic chorea without heart involvement
0.000 0.785 0.214
I02.0 Rheumatic chorea with heart involvement
0.000 0.785 0.214
E67.8 Other specified hyperalimentation
0.000 0.787 0.212
E67.3 Hypervitaminosis D
0.000 0.787 0.212
E67.2 Megavitamin-B6 syndrome
0.000 0.787 0.212
E67.1 Hypercarotenaemia
0.000 0.787 0.212
E67.0 Hypervitaminosis A
0.000 0.787 0.212
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.788 0.212
E29 Testicular dysfunction
0.000 0.790 0.210
E23.7 Disorder of pituitary gland, unspecified
0.000 0.790 0.210
E20 Hypoparathyroidism
0.000 0.794 0.206
E28 Ovarian dysfunction
0.000 0.794 0.206
E73.9 Lactose intolerance, unspecified
0.001 0.804 0.195
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.807 0.193
E23.1 Drug-induced hypopituitarism
0.000 0.807 0.193
E83.5 Disorders of calcium metabolism
0.165 0.819 0.016
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.820 0.180
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.820 0.179
E22.8 Other hyperfunction of pituitary gland
0.000 0.820 0.179
E21.3 Hyperparathyroidism, unspecified
0.000 0.820 0.180
I28 Other diseases of pulmonary vessels
0.001 0.823 0.176
E22.1 Hyperprolactinaemia
0.000 0.825 0.175
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.830 0.170
E34 Other endocrine disorders
0.000 0.831 0.169
E22.0 Acromegaly and pituitary gigantism
0.000 0.834 0.166
E55.0 Rickets, active
0.000 0.835 0.164
E25.9 Adrenogenital disorder, unspecified
0.000 0.836 0.164
E25.8 Other adrenogenital disorders
0.000 0.836 0.164
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.836 0.164
E30.9 Disorder of puberty, unspecified
0.000 0.836 0.164
E30.8 Other disorders of puberty
0.000 0.836 0.164
E30.1 Precocious puberty
0.000 0.836 0.164
E30.0 Delayed puberty
0.000 0.836 0.164
E31.9 Polyglandular dysfunction, unspecified
0.000 0.836 0.164
E31.8 Other polyglandular dysfunction
0.000 0.836 0.164
E31.1 Polyglandular hyperfunction
0.000 0.836 0.164
E31.0 Autoimmune polyglandular failure
0.000 0.836 0.164
E32.9 Disease of thymus, unspecified
0.000 0.836 0.164
E32.8 Other diseases of thymus
0.000 0.836 0.164
E32.1 Abscess of thymus
0.000 0.836 0.164
E32.0 Persistent hyperplasia of thymus
0.000 0.836 0.164
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.836 0.164
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.836 0.164
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.836 0.164
E26.9 Hyperaldosteronism, unspecified
0.000 0.838 0.162
E26.8 Other hyperaldosteronism
0.000 0.838 0.162
E26.1 Secondary hyperaldosteronism
0.000 0.838 0.162
E26.0 Primary hyperaldosteronism
0.000 0.840 0.160
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.841 0.159
E21.4 Other specified disorders of parathyroid gland
0.000 0.841 0.159
E21.2 Other hyperparathyroidism
0.000 0.841 0.159
E80.4 Gilbert's syndrome
0.001 0.841 0.158
I27 Other pulmonary heart diseases
0.000 0.842 0.158
E24.8 Other Cushing's syndrome
0.000 0.845 0.155
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.845 0.155
E24.3 Ectopic ACTH syndrome
0.000 0.845 0.155
E24.2 Drug-induced Cushing's syndrome
0.000 0.845 0.155
E24.1 Nelson's syndrome
0.000 0.845 0.155
E24.0 Pituitary-dependent Cushing's disease
0.000 0.845 0.155
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.001 0.847 0.152
E29.9 Testicular dysfunction, unspecified
0.000 0.849 0.151
E29.8 Other testicular dysfunction
0.000 0.849 0.151
E29.0 Testicular hyperfunction
0.000 0.849 0.151
E20.8 Other hypoparathyroidism
0.000 0.852 0.148

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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