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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2523511
log Bayes Factor = 65.5164
Chromosome 6   position 31,506,854  (GRCh37) Explore rs2523511 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.001 0.999
I25.1 Atherosclerotic heart disease
0.000 0.001 0.999
I20 Angina pectoris
0.000 0.003 0.997
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.003 0.997
I20.9 Angina pectoris, unspecified
0.000 0.010 0.990
E14.3 With ophthalmic complications
0.000 0.012 0.988
I25.5 Ischaemic cardiomyopathy
0.000 0.012 0.988
E10.1 With ketoacidosis
0.000 0.014 0.986
E14.9 Without complications
0.000 0.015 0.985
E10.4 With neurological complications
0.000 0.017 0.983
I22 Subsequent myocardial infarction
0.000 0.019 0.981
I20.0 Unstable angina
0.000 0.021 0.979
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.021 0.979
G35-G37 Demyelinating diseases of the central nervous system
0.968 0.032 0.000
E83.1 Disorders of iron metabolism
0.967 0.033 0.000
G37 Other demyelinating diseases of central nervous system
0.962 0.038 0.000
I25.2 Old myocardial infarction
0.000 0.040 0.960
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.047 0.953
I21 Acute myocardial infarction
0.000 0.054 0.946
G37.9 Demyelinating disease of central nervous system, unspecified
0.946 0.054 0.000
I10 Essential (primary) hypertension
0.000 0.060 0.940
E13 Other specified diabetes mellitus
0.000 0.071 0.929
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.072 0.928
E70-E90 Metabolic disorders
0.000 0.078 0.922
I24 Other acute ischaemic heart diseases
0.000 0.088 0.912
E78.8 Other disorders of lipoprotein metabolism
0.000 0.094 0.906
R07.4 Chest pain, unspecified
0.000 0.094 0.906
I21.9 Acute myocardial infarction, unspecified
0.000 0.095 0.905
L40-L45 Papulosquamous disorders
0.000 0.108 0.892
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.118 0.882
E10.2 With renal complications
0.000 0.118 0.882
E13.9 Without complications
0.000 0.122 0.878
E11.2 With renal complications
0.000 0.126 0.874
L43 Lichen planus
0.000 0.130 0.870
E11.0 With coma
0.000 0.135 0.865
I10-I15 Hypertensive diseases
0.000 0.147 0.853
I25.3 Aneurysm of heart
0.000 0.155 0.845
G37.8 Other specified demyelinating diseases of central nervous system
0.844 0.156 0.000
L43.9 Lichen planus, unspecified
0.000 0.161 0.839
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.163 0.837
E78.2 Mixed hyperlipidaemia
0.000 0.166 0.834
L40.8 Other psoriasis
0.000 0.167 0.833
I21.4 Acute subendocardial myocardial infarction
0.000 0.173 0.827
E11.1 With ketoacidosis
0.000 0.174 0.826
E14.4 With neurological complications
0.000 0.176 0.824
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.179 0.821
E10.5 With peripheral circulatory complications
0.000 0.180 0.820
E10.8 With unspecified complications
0.000 0.180 0.819
E00-E07 Disorders of thyroid gland
0.000 0.185 0.815
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.200 0.800
E10.0 With coma
0.000 0.207 0.793
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.784 0.216 0.000
I24.8 Other forms of acute ischaemic heart disease
0.000 0.217 0.783
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.220 0.780
L40.0 Psoriasis vulgaris
0.000 0.223 0.777
I23 Certain current complications following acute myocardial infarction
0.000 0.225 0.775
E11.6 With other specified complications
0.000 0.231 0.769
E03 Other hypothyroidism
0.000 0.236 0.764
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.237 0.763
E85 Amyloidosis
0.000 0.240 0.760
I15 Secondary hypertension
0.000 0.250 0.750
E03.9 Hypothyroidism, unspecified
0.000 0.252 0.748
E16 Other disorders of pancreatic internal secretion
0.000 0.257 0.743
E78.6 Lipoprotein deficiency
0.000 0.257 0.743
L43.8 Other lichen planus
0.000 0.263 0.737
E14.5 With peripheral circulatory complications
0.000 0.266 0.734
E10.6 With other specified complications
0.000 0.266 0.734
E05.9 Thyrotoxicosis, unspecified
0.000 0.267 0.733
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.278 0.722
E78.5 Hyperlipidaemia, unspecified
0.000 0.278 0.722
E14.6 With other specified complications
0.000 0.279 0.721
E74 Other disorders of carbohydrate metabolism
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E78.1 Pure hyperglyceridaemia
0.000 0.287 0.713
I12 Hypertensive renal disease
0.000 0.289 0.710
E78.3 Hyperchylomicronaemia
0.000 0.298 0.702
G36 Other acute disseminated demyelination
0.698 0.302 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.306 0.694
G37.5 Concentric sclerosis [Balo]
0.690 0.310 0.000
G37.4 Subacute necrotising myelitis
0.690 0.310 0.000
G37.2 Central pontine myelinolysis
0.690 0.310 0.000
G37.1 Central demyelination of corpus callosum
0.690 0.310 0.000
G37.0 Diffuse sclerosis
0.690 0.310 0.000
E11.5 With peripheral circulatory complications
0.000 0.314 0.686
I15.1 Hypertension secondary to other renal disorders
0.000 0.320 0.680
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.322 0.678
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.323 0.677
E16.2 Hypoglycaemia, unspecified
0.000 0.328 0.672
E13.8 With unspecified complications
0.000 0.334 0.666
E13.7 With multiple complications
0.000 0.334 0.666
E13.6 With other specified complications
0.000 0.334 0.666
E13.5 With peripheral circulatory complications
0.000 0.334 0.666
E13.4 With neurological complications
0.000 0.334 0.666
E13.3 With ophthalmic complications
0.000 0.334 0.666
E13.2 With renal complications
0.000 0.334 0.666
E13.1 With ketoacidosis
0.000 0.334 0.666
E13.0 With coma
0.000 0.334 0.666
E78.4 Other hyperlipidaemia
0.000 0.335 0.665
E79 Disorders of purine and pyrimidine metabolism
0.000 0.338 0.661
E77 Disorders of glycoprotein metabolism
0.000 0.339 0.661
E76 Disorders of glycosaminoglycan metabolism
0.000 0.339 0.661
E72 Other disorders of amino-acid metabolism
0.000 0.339 0.661
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.339 0.661
E70 Disorders of aromatic amino-acid metabolism
0.000 0.339 0.661
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.339 0.661
I11 Hypertensive heart disease
0.000 0.341 0.659
I22.8 Subsequent myocardial infarction of other sites
0.000 0.342 0.658
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.348 0.652
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.350 0.650
L42 Pityriasis rosea
0.000 0.353 0.647
E85.9 Amyloidosis, unspecified
0.000 0.356 0.644
L44 Other papulosquamous disorders
0.000 0.360 0.640
L41 Parapsoriasis
0.000 0.360 0.640
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.360 0.640
I12.9 Hypertensive renal disease without renal failure
0.000 0.366 0.634
L43.3 Subacute (active) lichen planus
0.000 0.376 0.623
L43.2 Lichenoid drug reaction
0.000 0.376 0.623
L43.1 Bullous lichen planus
0.000 0.376 0.623
L43.0 Hypertrophic lichen planus
0.000 0.376 0.623
I23.8 Other current complications following acute myocardial infarction
0.000 0.386 0.614
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.388 0.612
I13 Hypertensive heart and renal disease
0.000 0.388 0.612
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.391 0.609
I20.1 Angina pectoris with documented spasm
0.000 0.394 0.606
E84 Cystic fibrosis
0.000 0.395 0.605
E11.4 With neurological complications
0.000 0.409 0.591
E15 Nondiabetic hypoglycaemic coma
0.000 0.412 0.588
E40-E46 Malnutrition
0.000 0.413 0.587
E16.1 Other hypoglycaemia
0.000 0.415 0.585
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.416 0.584
E00 Congenital iodine-deficiency syndrome
0.000 0.416 0.584
I25.4 Coronary artery aneurysm
0.000 0.419 0.581
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.427 0.573
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.444 0.556
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.444 0.556
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.444 0.556
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.444 0.556
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.444 0.556
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.444 0.556
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.444 0.556
E85.4 Organ-limited amyloidosis
0.000 0.445 0.555
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.447 0.553
E03.5 Myxoedema coma
0.000 0.452 0.548
E03.4 Atrophy of thyroid (acquired)
0.000 0.452 0.548
E03.3 Postinfectious hypothyroidism
0.000 0.452 0.548
E03.1 Congenital hypothyroidism without goitre
0.000 0.452 0.548
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.452 0.548
E05.5 Thyroid crisis or storm
0.000 0.453 0.547
E05.4 Thyrotoxicosis factitia
0.000 0.453 0.547
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.453 0.547
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.453 0.547
Chapter IX Diseases of the circulatory system
0.000 0.454 0.546
E85.8 Other amyloidosis
0.000 0.455 0.545
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.455 0.545
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.455 0.545
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.455 0.545
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.461 0.539
E73 Lactose intolerance
0.000 0.462 0.538
I15.8 Other secondary hypertension
0.000 0.462 0.538
I15.2 Hypertension secondary to endocrine disorders
0.000 0.462 0.538
I15.0 Renovascular hypertension
0.000 0.462 0.538
E11.3 With ophthalmic complications
0.000 0.465 0.535
E89.3 Postprocedural hypopituitarism
0.000 0.466 0.534
E85.3 Secondary systemic amyloidosis
0.000 0.467 0.533
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.467 0.533
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.467 0.533
E16.4 Abnormal secretion of gastrin
0.000 0.467 0.533
E16.3 Increased secretion of glucagon
0.000 0.467 0.533
E07 Other disorders of thyroid
0.000 0.469 0.531
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.471 0.528
I15.9 Seconday hypertension, unspecified
0.000 0.473 0.527
I24.1 Dressler's syndrome
0.000 0.480 0.520
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.484 0.515
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.484 0.515
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.484 0.515
E74.2 Disorders of galactose metabolism
0.000 0.484 0.515
E74.1 Disorders of fructose metabolism
0.000 0.484 0.515
E74.0 Glycogen storage disease
0.000 0.484 0.515
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E83 Disorders of mineral metabolism
0.391 0.486 0.123
G36.0 Neuromyelitis optica [Devic]
0.504 0.496 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.496 0.503
E11.8 With unspecified complications
0.000 0.499 0.500
G36.9 Acute disseminated demyelination, unspecified
0.500 0.499 0.000
G36.8 Other specified acute disseminated demyelination
0.500 0.499 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.500 0.499 0.000
E06 Thyroiditis
0.000 0.501 0.499
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.507 0.493
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.507 0.493
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.525 0.475
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.525 0.474
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.525 0.474
E79.1 Lesch-Nyhan syndrome
0.000 0.525 0.474
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.526 0.474
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.526 0.474
E70.3 Albinism
0.000 0.526 0.474
E70.2 Disorders of tyrosine metabolism
0.000 0.526 0.474
E70.1 Other hyperphenylalaninaemias
0.000 0.526 0.474
E70.0 Classical phenylketonuria
0.000 0.526 0.474
E71.3 Disorders of fatty-acid metabolism
0.000 0.526 0.474
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.526 0.474
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.526 0.474
E71.0 Maple-syrup-urine disease
0.000 0.526 0.474
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.526 0.474
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.526 0.474
E72.5 Disorders of glycine metabolism
0.000 0.526 0.474
E72.4 Disorders of ornithine metabolism
0.000 0.526 0.474
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.526 0.474
E72.2 Disorders of urea cycle metabolism
0.000 0.526 0.474
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.526 0.474
E72.0 Disorders of amino-acid transport
0.000 0.526 0.474
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.526 0.474
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.526 0.474
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.526 0.474
E76.2 Other mucopolysaccharidoses
0.000 0.526 0.474
E76.1 Mucopolysaccharidosis, type II
0.000 0.526 0.474
E76.0 Mucopolysaccharidosis, type I
0.000 0.526 0.474
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.526 0.474
E77.8 Other disorders of glycoprotein metabolism
0.000 0.526 0.474
E77.1 Defects in glycoprotein degradation
0.000 0.526 0.474
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.526 0.474
E75.6 Lipid storage disorder, unspecified
0.000 0.532 0.467
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.532 0.467
E75.3 Sphingolipidosis, unspecified
0.000 0.532 0.467
E75.2 Other sphingolipidosis
0.000 0.532 0.467
E75.1 Other gangliosidosis
0.000 0.532 0.467
E75.0 GM2 gangliosidosis
0.000 0.532 0.467
L41.9 Parapsoriasis, unspecified
0.000 0.541 0.459
L41.8 Other parapsoriasis
0.000 0.541 0.459
L41.5 Retiform parapsoriasis
0.000 0.541 0.459
L41.4 Large plaque parapsoriasis
0.000 0.541 0.459
L41.3 Small plaque parapsoriasis
0.000 0.541 0.459
L41.2 Lymphomatoid papulosis
0.000 0.541 0.459
L41.1 Pityriasis lichenoides chronica
0.000 0.541 0.459
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.541 0.459
L44.9 Papulosquamous disorder, unspecified
0.000 0.541 0.459
L44.8 Other specified papulosquamous disorders
0.000 0.541 0.459
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.541 0.459
L44.3 Lichen ruber moniliformis
0.000 0.541 0.459
L44.2 Lichen striatus
0.000 0.541 0.459
L44.1 Lichen nitidus
0.000 0.541 0.459
L44.0 Pityriasis rubra pilaris
0.000 0.541 0.459
E75.5 Other lipid storage disorders
0.000 0.541 0.458
E88 Other metabolic disorders
0.000 0.542 0.458
E05.8 Other thyrotoxicosis
0.000 0.552 0.448
E65-E68 Obesity and other hyperalimentation
0.000 0.555 0.444
I12.0 Hypertensive renal disease with renal failure
0.000 0.558 0.442
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.561 0.439
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.561 0.439
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.561 0.439
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.561 0.439
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.563 0.437
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.563 0.437
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.563 0.437
E89.5 Postprocedural testicular hypofunction
0.000 0.563 0.437
E89.1 Postprocedural hypoinsulinaemia
0.000 0.563 0.437
E84.8 Cystic fibrosis with other manifestations
0.000 0.566 0.434
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.566 0.434
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.566 0.434
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.579 0.421
E45 Retarded development following protein-energy malnutrition
0.000 0.579 0.421
E43 Unspecified severe protein-energy malnutrition
0.000 0.579 0.421
E42 Marasmic kwashiorkor
0.000 0.579 0.421
E41 Nutritional marasmus
0.000 0.579 0.421
E40 Kwashiorkor
0.000 0.579 0.421
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.581 0.419
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.581 0.419
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.581 0.419
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.581 0.419
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.581 0.419
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.581 0.419
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.581 0.419
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.581 0.419
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.585 0.415
E89.4 Postprocedural ovarian failure
0.000 0.590 0.410
E50-E64 Other nutritional deficiencies
0.000 0.592 0.408
K90 Intestinal malabsorption
0.000 0.594 0.406
I00-I02 Acute rheumatic fever
0.000 0.608 0.392
E73.8 Other lactose intolerance
0.000 0.614 0.386
E73.1 Secondary lactase deficiency
0.000 0.614 0.386
E73.0 Congenital lactase deficiency
0.000 0.614 0.386
E89.2 Postprocedural hypoparathyroidism
0.000 0.614 0.385
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.619 0.381
E07.1 Dyshormogenetic goitre
0.000 0.619 0.381
E07.0 Hypersecretion of calcitonin
0.000 0.619 0.381
E07.8 Other specified disorders of thyroid
0.000 0.621 0.379
E84.9 Cystic fibrosis, unspecified
0.001 0.621 0.378
E83.3 Disorders of phosphorus metabolism
0.339 0.623 0.038
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.625 0.375
E80.6 Other disorders of bilirubin metabolism
0.000 0.630 0.370
E83.9 Disorder of mineral metabolism, unspecified
0.280 0.632 0.088
E83.8 Other disorders of mineral metabolism
0.280 0.632 0.088
E83.2 Disorders of zinc metabolism
0.280 0.632 0.088
E83.0 Disorders of copper metabolism
0.280 0.632 0.088
E88.2 Lipomatosis, not elsewhere classified
0.000 0.636 0.364
E06.5 Other chronic thyroiditis
0.000 0.642 0.358
E06.4 Drug-induced thyroiditis
0.000 0.642 0.358
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.642 0.358
E06.1 Subacute thyroiditis
0.000 0.642 0.358
E06.0 Acute thyroiditis
0.000 0.642 0.358
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.646 0.353
E80.5 Crigler-Najjar syndrome
0.000 0.646 0.353
E80.3 Defects of catalase and peroxydase
0.000 0.646 0.353
E80.2 Other porphyria
0.000 0.646 0.353
E80.1 Porphyria cutanea tarda
0.000 0.646 0.353
E80.0 Hereditary erythropoietic porphyria
0.000 0.646 0.353
E46 Unspecified protein-energy malnutrition
0.000 0.657 0.343
E06.9 Thyroiditis, unspecified
0.000 0.660 0.340
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.667 0.333
E07.9 Disorder of thyroid, unspecified
0.000 0.669 0.331
E88.8 Other specified metabolic disorders
0.000 0.670 0.330
E88.9 Metabolic disorder, unspecified
0.000 0.671 0.328
E88.3 Tumour lysis syndrome
0.000 0.675 0.325
E03.8 Other specified hypothyroidism
0.001 0.675 0.324
E67 Other hyperalimentation
0.000 0.681 0.319
E68 Sequelae of hyperalimentation
0.000 0.681 0.319
E65 Localised adiposity
0.000 0.690 0.310
E61 Deficiency of other nutrient elements
0.000 0.695 0.305
E44.1 Mild protein-energy malnutrition
0.000 0.698 0.302
E44.0 Moderate protein-energy malnutrition
0.000 0.698 0.302
E06.3 Autoimmune thyroiditis
0.000 0.701 0.299
K90.9 Intestinal malabsorption, unspecified
0.000 0.701 0.299
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.707 0.292
E63 Other nutritional deficiencies
0.000 0.707 0.292
E56 Other vitamin deficiencies
0.000 0.707 0.292
E51 Thiamine deficiency
0.000 0.707 0.292
E50 Vitamin A deficiency
0.000 0.707 0.292
E60 Dietary zinc deficiency
0.000 0.707 0.292
E59 Dietary selenium deficiency
0.000 0.707 0.292
E58 Dietary calcium deficiency
0.000 0.707 0.292
E54 Ascorbic acid deficiency
0.000 0.707 0.292
E52 Niacin deficiency [pellagra]
0.000 0.707 0.292
K90.3 Pancreatic steatorrhoea
0.000 0.709 0.291
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.709 0.291
K90.1 Tropical sprue
0.000 0.709 0.291
K90.8 Other intestinal malabsorption
0.000 0.709 0.291
I02 Rheumatic chorea
0.000 0.719 0.281
I01 Rheumatic fever with heart involvement
0.000 0.719 0.281
I00 Rheumatic fever without mention of heart involvement
0.000 0.719 0.281
E20-E35 Disorders of other endocrine glands
0.000 0.725 0.275
E89.0 Postprocedural hypothyroidism
0.000 0.734 0.266
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.735 0.264
E73.9 Lactose intolerance, unspecified
0.001 0.737 0.263
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.739 0.261
E61.1 Iron deficiency
0.000 0.761 0.239
E55 Vitamin D deficiency
0.000 0.768 0.232
E67.8 Other specified hyperalimentation
0.000 0.771 0.229
E67.3 Hypervitaminosis D
0.000 0.771 0.229
E67.2 Megavitamin-B6 syndrome
0.000 0.771 0.229
E67.1 Hypercarotenaemia
0.000 0.771 0.229
E67.0 Hypervitaminosis A
0.000 0.771 0.229
E23 Hypofunction and other disorders of pituitary gland
0.000 0.772 0.228
E22 Hyperfunction of pituitary gland
0.000 0.780 0.220
E61.9 Deficiency of nutrient element, unspecified
0.000 0.781 0.219
E61.8 Deficiency of other specified nutrient elements
0.000 0.781 0.219
E61.7 Deficiency of multiple nutrient elements
0.000 0.781 0.219
E61.6 Vanadium deficiency
0.000 0.781 0.219
E61.5 Molybdenum deficiency
0.000 0.781 0.219
E61.4 Chromium deficiency
0.000 0.781 0.219
E61.3 Manganese deficiency
0.000 0.781 0.219
E61.0 Copper deficiency
0.000 0.781 0.219
E50.9 Vitamin A deficiency, unspecified
0.000 0.790 0.210
E50.8 Other manifestations of vitamin A deficiency
0.000 0.790 0.210
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.790 0.210
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.790 0.210
E50.5 Vitamin A deficiency with night blindness
0.000 0.790 0.210
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.790 0.210
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.790 0.210
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.790 0.210
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.790 0.210
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.790 0.210
E51.9 Thiamine deficiency, unspecified
0.000 0.790 0.210
E51.8 Other manifestations of thiamine deficiency
0.000 0.790 0.210
E51.2 Wernicke's encephalopathy
0.000 0.790 0.210
E51.1 Beriberi
0.000 0.790 0.210
E56.9 Vitamin deficiency, unspecified
0.000 0.790 0.210
E56.8 Deficiency of other vitamins
0.000 0.790 0.210
E56.1 Deficiency of vitamin K
0.000 0.790 0.210
E56.0 Deficiency of vitamin E
0.000 0.790 0.210
E63.9 Nutritional deficiency, unspecified
0.000 0.790 0.210
E63.8 Other specified nutritional deficiencies
0.000 0.790 0.210
E63.1 Imbalance of constituents of food intake
0.000 0.790 0.210
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.790 0.210
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.790 0.210
E64.8 Sequelae of other nutritional deficiencies
0.000 0.790 0.210
E64.3 Sequelae of rickets
0.000 0.790 0.210
E64.2 Sequelae of vitamin C deficiency
0.000 0.790 0.210
E64.1 Sequelae of vitamin A deficiency
0.000 0.790 0.210
E64.0 Sequelae of protein-energy malnutrition
0.000 0.790 0.210
E61.2 Magnesium deficiency
0.000 0.790 0.210
E83.4 Disorders of magnesium metabolism
0.128 0.792 0.081
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.794 0.205
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.798 0.201
I01.8 Other acute rheumatic heart disease
0.000 0.798 0.201
I01.2 Acute rheumatic myocarditis
0.000 0.798 0.201
I01.1 Acute rheumatic endocarditis
0.000 0.798 0.201
I01.0 Acute rheumatic pericarditis
0.000 0.798 0.201
I02.9 Rheumatic chorea without heart involvement
0.000 0.798 0.201
I02.0 Rheumatic chorea with heart involvement
0.000 0.798 0.201
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.803 0.197
E32 Diseases of thymus
0.000 0.803 0.197
E31 Polyglandular dysfunction
0.000 0.803 0.197
E30 Disorders of puberty, not elsewhere classified
0.000 0.803 0.197
E25 Adrenogenital disorders
0.000 0.803 0.197
E26 Hyperaldosteronism
0.000 0.807 0.193
E23.6 Other disorders of pituitary gland
0.000 0.809 0.191
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.812 0.188
E23.2 Diabetes insipidus
0.000 0.813 0.187
E29 Testicular dysfunction
0.000 0.815 0.184
E24 Cushing's syndrome
0.000 0.816 0.184
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.817 0.183
E20 Hypoparathyroidism
0.000 0.823 0.177
E23.7 Disorder of pituitary gland, unspecified
0.000 0.827 0.173
E28 Ovarian dysfunction
0.000 0.829 0.171
E55.0 Rickets, active
0.000 0.833 0.166
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.835 0.165
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.837 0.163
E23.1 Drug-induced hypopituitarism
0.000 0.837 0.163
E22.1 Hyperprolactinaemia
0.000 0.842 0.158
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.842 0.158
E22.8 Other hyperfunction of pituitary gland
0.000 0.842 0.158
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.001 0.845 0.154
E83.5 Disorders of calcium metabolism
0.126 0.848 0.026
I28 Other diseases of pulmonary vessels
0.001 0.855 0.144
E80.4 Gilbert's syndrome
0.001 0.856 0.143
E22.0 Acromegaly and pituitary gigantism
0.000 0.857 0.143
E34 Other endocrine disorders
0.000 0.858 0.142
E25.9 Adrenogenital disorder, unspecified
0.000 0.858 0.141
E25.8 Other adrenogenital disorders
0.000 0.858 0.141
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.858 0.141
E30.9 Disorder of puberty, unspecified
0.000 0.858 0.141
E30.8 Other disorders of puberty
0.000 0.858 0.141
E30.1 Precocious puberty
0.000 0.858 0.141
E30.0 Delayed puberty
0.000 0.858 0.141
E31.9 Polyglandular dysfunction, unspecified
0.000 0.858 0.141
E31.8 Other polyglandular dysfunction
0.000 0.858 0.141
E31.1 Polyglandular hyperfunction
0.000 0.858 0.141
E31.0 Autoimmune polyglandular failure
0.000 0.858 0.141
E32.9 Disease of thymus, unspecified
0.000 0.858 0.141
E32.8 Other diseases of thymus
0.000 0.858 0.141
E32.1 Abscess of thymus
0.000 0.858 0.141
E32.0 Persistent hyperplasia of thymus
0.000 0.858 0.141
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.858 0.141
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.858 0.141
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.858 0.141
E21.3 Hyperparathyroidism, unspecified
0.000 0.859 0.141
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.861 0.139
E26.9 Hyperaldosteronism, unspecified
0.000 0.861 0.139
E26.8 Other hyperaldosteronism
0.000 0.861 0.139
E26.1 Secondary hyperaldosteronism
0.000 0.861 0.139
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.864 0.136
E26.0 Primary hyperaldosteronism
0.000 0.865 0.135
E53 Deficiency of other B group vitamins
0.001 0.867 0.132
E29.9 Testicular dysfunction, unspecified
0.000 0.867 0.132
E29.8 Other testicular dysfunction
0.000 0.867 0.132
E29.0 Testicular hyperfunction
0.000 0.867 0.132
E24.8 Other Cushing's syndrome
0.000 0.868 0.132
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.868 0.132
E24.3 Ectopic ACTH syndrome
0.000 0.868 0.132
E24.2 Drug-induced Cushing's syndrome
0.000 0.868 0.132
E24.1 Nelson's syndrome
0.000 0.868 0.132
E24.0 Pituitary-dependent Cushing's disease
0.000 0.868 0.132
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.869 0.131
E21.4 Other specified disorders of parathyroid gland
0.000 0.869 0.131
E21.2 Other hyperparathyroidism
0.000 0.869 0.131

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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