TreeWAS – Variant ID: rs2523547

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	1.000
E03 Other hypothyroidism	0.000	1.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	1.000
# Top node	0.001	0.999
L40-L45 Papulosquamous disorders	0.003	0.997
L40 Psoriasis	0.003	0.997
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.005	0.995
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.005	0.995
E65-E68 Obesity and other hyperalimentation	0.008	0.992
L57 Skin changes due to chronic exposure to nonionising radiation	0.009	0.991
L40.5 Arthropathic psoriasis	0.012	0.988
E66 Obesity	0.013	0.987
L40.9 Psoriasis, unspecified	0.014	0.986
E66.8 Other obesity	0.015	0.985
D50-D53 Nutritional anaemias	0.016	0.984
L57.0 Actinic keratosis	0.016	0.984
M06.9 Rheumatoid arthritis, unspecified	0.019	0.981
D50 Iron deficiency anaemia	0.019	0.981
M06 Other rheumatoid arthritis	0.022	0.978
M05-M14 Inflammatory polyarthropathies	0.023	0.977
D50.9 Iron deficiency anaemia, unspecified	0.023	0.977
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.025	0.975
L00-L08 Infections of the skin and subcutaneous tissue	0.028	0.972
Chapter I Certain infectious and parasitic diseases	0.028	0.972
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.030	0.970
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.032	0.968
Chapter VIII Diseases of the ear and mastoid process	0.037	0.963
B35-B49 Mycoses	0.038	0.962
E70-E90 Metabolic disorders	0.038	0.962
B37 Candidiasis	0.041	0.959
L02 Cutaneous abscess, furuncle and carbuncle	0.044	0.956
B37.8 Candidiasis of other sites	0.045	0.955
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.053	0.947
H65-H75 Diseases of middle ear and mastoid	0.063	0.937
H72 Perforation of tympanic membrane	0.076	0.924
B25-B34 Other viral diseases	0.076	0.924
L20-L30 Dermatitis and eczema	0.083	0.917
H72.9 Perforation of tympanic membrane, unspecified	0.083	0.917
E06 Thyroiditis	0.093	0.907
B37.0 Candidal stomatitis	0.099	0.901
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.100	0.900
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.103	0.897
M07 Psoriatic and enteropathic arthropathies	0.104	0.896
M45-M49 Spondylopathies	0.106	0.894
B34 Viral infection of unspecified site	0.115	0.885
M45 Ankylosing spondylitis	0.117	0.883
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.122	0.878
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.126	0.874
E10-E14 Diabetes mellitus	0.127	0.873
M45.X9 Ankylosing spondylitis (Site unspecified)	0.132	0.868
Chapter V Mental and behavioural disorders	0.132	0.868
E05 Thyrotoxicosis [hyperthyroidism]	0.145	0.855
H65 Nonsuppurative otitis media	0.150	0.850
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.158	0.842
B34.9 Viral infection, unspecified	0.158	0.842
E10 Insulin-dependent diabetes mellitus	0.158	0.842
H80-H83 Diseases of inner ear	0.159	0.841
E87 Other disorders of fluid, electrolyte and acid-base balance	0.160	0.840
M07.3 Other psoriatic arthropathies	0.163	0.837
D80-D89 Certain disorders involving the immune mechanism	0.163	0.837
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.165	0.835
E06.3 Autoimmune thyroiditis	0.171	0.829
L29 Pruritus	0.172	0.828
E89.0 Postprocedural hypothyroidism	0.173	0.827
D68 Other coagulation defects	0.173	0.827
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.173	0.827
M05 Seropositive rheumatoid arthritis	0.175	0.825
M35 Other systemic involvement of connective tissue	0.184	0.816
L08 Other local infections of skin and subcutaneous tissue	0.185	0.815
M35.3 Polymyalgia rheumatica	0.186	0.814
M20-M25 Other joint disorders	0.187	0.813
B20-B24 Human immunodeficiency virus [HIV] disease	0.192	0.808
M95.0 Acquired deformity of nose	0.194	0.806
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.194	0.806
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.195	0.805
E20-E35 Disorders of other endocrine glands	0.198	0.802
E86 Volume depletion	0.199	0.801
M06.0 Seronegative rheumatoid arthritis	0.212	0.788
L29.0 Pruritus ani	0.214	0.786
B35 Dermatophytosis	0.218	0.782
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.218	0.782
D86 Sarcoidosis	0.225	0.775
E87.1 Hypo-osmolality and hyponatraemia	0.227	0.773
E27 Other disorders of adrenal gland	0.232	0.768
B99-B99 Other infectious diseases	0.233	0.767
H72.0 Central perforation of tympanic membrane	0.234	0.766
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.236	0.764
E05.0 Thyrotoxicosis with diffuse goitre	0.237	0.763
D55-D59 Haemolytic anaemias	0.239	0.761
M07.30 Other psoriatic arthropathies (Multiple sites)	0.239	0.761
E73 Lactose intolerance	0.241	0.759
E66.0 Obesity due to excess calories	0.248	0.752
E88 Other metabolic disorders	0.250	0.750
A50-A64 Infections with a predominantly sexual mode of transmission	0.252	0.748
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.253	0.747
H80 Otosclerosis	0.253	0.747
L56 Other acute skin changes due to ultraviolet radiation	0.256	0.744
H65.9 Nonsuppurative otitis media, unspecified	0.257	0.743
E27.1 Primary adrenocortical insufficiency	0.257	0.743
M00-M03 Infectious arthropathies	0.259	0.741
E10.3 With ophthalmic complications	0.260	0.740
L30 Other dermatitis	0.266	0.734
Chapter XXII Codes for special purposes	0.268	0.732
B34.8 Other viral infections of unspecified site	0.268	0.732
E10.9 Without complications	0.270	0.730
L05 Pilonidal cyst	0.273	0.727
F00-F09 Organic, including symptomatic, mental disorders	0.278	0.722
E65 Localised adiposity	0.279	0.721
E80 Disorders of porphyrin and bilirubin metabolism	0.281	0.719
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.281	0.719
E87.2 Acidosis	0.282	0.718
D68.5 Primary Thrombophilia	0.282	0.718
M35.0 Sicca syndrome [Sjogren]	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.283	0.717
E03.5 Myxoedema coma	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.283	0.717
Chapter XVI Certain conditions originating in the perinatal period	0.283	0.716
E50-E64 Other nutritional deficiencies	0.284	0.716
M05.9 Seropositive rheumatoid arthritis, unspecified	0.284	0.716
L44 Other papulosquamous disorders	0.285	0.715
L41 Parapsoriasis	0.285	0.715
L45 Papulosquamous disorders in diseases classified elsewhere	0.285	0.715
L27 Dermatitis due to substances taken internally	0.285	0.715
L40.8 Other psoriasis	0.285	0.715
L40.4 Guttate psoriasis	0.285	0.715
L40.3 Pustulosis palmaris et plantaris	0.285	0.715
L40.2 Acrodermatitis continua	0.285	0.715
L40.1 Generalised pustular psoriasis	0.285	0.715
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.287	0.713
L58 Radiodermatitis	0.287	0.713
L55 Sunburn	0.287	0.713
E67 Other hyperalimentation	0.288	0.711
E68 Sequelae of hyperalimentation	0.288	0.711
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.289	0.711
L57.5 Actinic granuloma	0.289	0.711
L57.3 Poikiloderma of Civatte	0.289	0.711
L57.2 Cutis rhomboidalis nuchae	0.289	0.711
L57.1 Actinic reticuloid	0.289	0.711
D86.9 Sarcoidosis, unspecified	0.290	0.710
M07.39 Other psoriatic arthropathies (Site unspecified)	0.292	0.708
E66.1 Drug-induced obesity	0.292	0.708
F30-F39 Mood [affective] disorders	0.293	0.707
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.294	0.706
M06.98 Rheumatoid arthritis, unspecified (Other)	0.297	0.703
D50.1 Sideropenic dysphagia	0.297	0.703
H73 Other disorders of tympanic membrane	0.298	0.702
M14 Arthropathies in other diseases classified elsewhere	0.298	0.702
M06.8 Other specified rheumatoid arthritis	0.298	0.701
M06.2 Rheumatoid bursitis	0.298	0.701
M06.1 Adult-onset Still's disease	0.298	0.701
M12 Other specific arthropathies	0.299	0.701
M09 Juvenile arthritis in diseases classified elsewhere	0.299	0.701
M08 Juvenile arthritis	0.299	0.701
E74 Other disorders of carbohydrate metabolism	0.301	0.699
B25 Cytomegaloviral disease	0.302	0.698
D68.9 Coagulation defect, unspecified	0.302	0.698
F40-F48 Neurotic, stress-related and somatoform disorders	0.302	0.698
L04 Acute lymphadenitis	0.303	0.697
L01 Impetigo	0.303	0.697
L00 Staphylococcal scalded skin syndrome	0.303	0.697
M34 Systemic sclerosis	0.303	0.697
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.303	0.697
A75-A79 Rickettsioses	0.303	0.697
A70-A74 Other diseases caused by chlamydiae	0.303	0.697
A65-A69 Other spirochaetal diseases	0.303	0.697
A20-A28 Certain zoonotic bacterial diseases	0.303	0.697
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.304	0.696
E10.1 With ketoacidosis	0.304	0.696
F80-F89 Disorders of psychological development	0.305	0.695
B24 Unspecified human immunodeficiency virus [HIV] disease	0.308	0.691
B48 Other mycoses, not elsewhere classified	0.310	0.690
B47 Mycetoma	0.310	0.690
B46 Zygomycosis	0.310	0.690
B45 Cryptococcosis	0.310	0.690
B43 Chromomycosis and phaeomycotic abscess	0.310	0.690
B42 Sporotrichosis	0.310	0.690
B41 Paracoccidioidomycosis	0.310	0.690
B40 Blastomycosis	0.310	0.690
B39 Histoplasmosis	0.310	0.690
B38 Coccidioidomycosis	0.310	0.690
B36 Other superficial mycoses	0.310	0.690
E84 Cystic fibrosis	0.310	0.690
E79 Disorders of purine and pyrimidine metabolism	0.310	0.690
E77 Disorders of glycoprotein metabolism	0.310	0.690
E76 Disorders of glycosaminoglycan metabolism	0.310	0.690
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.310	0.690
E72 Other disorders of amino-acid metabolism	0.310	0.690
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.310	0.690
E70 Disorders of aromatic amino-acid metabolism	0.310	0.690
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.310	0.690
Chapter IX Diseases of the circulatory system	0.311	0.689
B37.7 Candidal septicaemia	0.313	0.687
B37.6 Candidal endocarditis	0.313	0.687
B37.5 Candidal meningitis	0.313	0.687
E06.9 Thyroiditis, unspecified	0.313	0.687
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.315	0.685
H60-H62 Diseases of external ear	0.318	0.682
L57.4 Cutis laxa senilis	0.318	0.682
F60-F69 Disorders of adult personality and behaviour	0.321	0.679
H80.9 Otosclerosis, unspecified	0.321	0.679
A15-A19 Tuberculosis	0.321	0.678
H83 Other diseases of inner ear	0.322	0.678
L10-L14 Bullous disorders	0.322	0.677
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.323	0.677
M46 Other inflammatory spondylopathies	0.324	0.675
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.328	0.671
H68 Eustachian salpingitis and obstruction	0.328	0.671
H67 Otitis media in diseases classified elsewhere	0.328	0.671
H70 Mastoiditis and related conditions	0.330	0.670
E40-E46 Malnutrition	0.331	0.669
B50-B64 Protozoal diseases	0.331	0.669
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.331	0.668
M35.7 Hypermobility syndrome	0.332	0.668
L28 Lichen simplex chronicus and prurigo	0.333	0.667
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.333	0.667
H65.2 Chronic serous otitis media	0.335	0.665
E14 Unspecified diabetes mellitus	0.335	0.665
H72.1 Attic perforation of tympanic membrane	0.337	0.663
B33 Other viral diseases, not elsewhere classified	0.337	0.662
B30 Viral conjunctivitis	0.337	0.662
B27 Infectious mononucleosis	0.337	0.662
B26 Mumps	0.337	0.662
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.338	0.662
D86.0 Sarcoidosis of lung	0.339	0.661
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.339	0.661
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.339	0.660
E03.8 Other specified hypothyroidism	0.340	0.659
H65.4 Other chronic nonsuppurative otitis media	0.342	0.658
L24 Irritant contact dermatitis	0.342	0.658
L21 Seborrhoeic dermatitis	0.342	0.658
L26 Exfoliative dermatitis	0.342	0.658
L22 Diaper [napkin] dermatitis	0.342	0.658
E10.2 With renal complications	0.343	0.657
M11 Other crystal arthropathies	0.344	0.656
E66.2 Extreme obesity with alveolar hypoventilation	0.345	0.655
E10.5 With peripheral circulatory complications	0.346	0.654
D60-D64 Aplastic and other anaemias	0.346	0.654
B15-B19 Viral hepatitis	0.347	0.653
E06.5 Other chronic thyroiditis	0.350	0.650
E06.4 Drug-induced thyroiditis	0.350	0.650
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.350	0.650
E06.1 Subacute thyroiditis	0.350	0.650
E06.0 Acute thyroiditis	0.350	0.650
L20 Atopic dermatitis	0.350	0.650
D52 Folate deficiency anaemia	0.353	0.647
B37.9 Candidiasis, unspecified	0.354	0.646
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.354	0.646
D66 Hereditary factor VIII deficiency	0.355	0.645
B35.1 Tinea unguium	0.356	0.644
D67 Hereditary factor IX deficiency	0.357	0.643
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.357	0.643
F31 Bipolar affective disorder	0.357	0.643
E85 Amyloidosis	0.357	0.643
M07.6 Other enteropathic arthropathies	0.358	0.642
M07.5 Arthropathy in ulcerative colitis	0.358	0.642
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.358	0.642
M07.2 Psoriatic spondylitis	0.358	0.642
M07.1 Arthritis mutilans	0.358	0.642
M07.0 Distal interphalangeal psoriatic arthropathy	0.358	0.642
M06.4 Inflammatory polyarthropathy	0.358	0.642
B90-B94 Sequelae of infectious and parasitic diseases	0.358	0.642
I60-I69 Cerebrovascular diseases	0.359	0.641
L25 Unspecified contact dermatitis	0.361	0.639
D69 Purpura and other haemorrhagic conditions	0.361	0.639
D51 Vitamin B12 deficiency anaemia	0.361	0.639
E22 Hyperfunction of pituitary gland	0.364	0.636
I20-I25 Ischaemic heart diseases	0.364	0.636
B37.4 Candidiasis of other urogenital sites	0.364	0.635
E87.7 Fluid overload	0.365	0.634
B34.3 Parvovirus infection, unspecified	0.366	0.634
B34.2 Coronavirus infection, unspecified	0.366	0.634
B34.1 Enterovirus infection, unspecified	0.366	0.634
B34.0 Adenovirus infection, unspecified	0.366	0.634
D68.0 Von Willebrand's disease	0.366	0.634
B65-B83 Helminthiases	0.367	0.633
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.367	0.633
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.367	0.633
M45.X6 Ankylosing spondylitis (Lumbar region)	0.367	0.633
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.367	0.633
M45.X4 Ankylosing spondylitis (Thoracic region)	0.367	0.633
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.367	0.633
M45.X2 Ankylosing spondylitis (Cervical region)	0.367	0.633
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.367	0.633
E10.4 With neurological complications	0.368	0.632
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.369	0.631
B85-B89 Pediculosis, acariasis and other infestations	0.369	0.631
B37.1 Pulmonary candidiasis	0.370	0.630
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.370	0.630
E89.8 Other postprocedural endocrine and metabolic disorders	0.370	0.630
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.370	0.630
E89.5 Postprocedural testicular hypofunction	0.370	0.630
E89.4 Postprocedural ovarian failure	0.370	0.630
E89.1 Postprocedural hypoinsulinaemia	0.370	0.630
I21 Acute myocardial infarction	0.371	0.629
M06.3 Rheumatoid nodule	0.371	0.629
M99 Biomechanical lesions, not elsewhere classified	0.373	0.627
E12 Malnutrition-related diabetes mellitus	0.374	0.626
M49 Spondylopathies in diseases classified elsewhere	0.375	0.625
L05.0 Pilonidal cyst with abscess	0.376	0.624
D70-D77 Other diseases of blood and blood-forming organs	0.376	0.624
E07 Other disorders of thyroid	0.377	0.623
I70-I79 Diseases of arteries, arterioles and capillaries	0.377	0.623
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.378	0.622
L23 Allergic contact dermatitis	0.378	0.622
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.378	0.622
B37.2 Candidiasis of skin and nail	0.378	0.622
H65.3 Chronic mucoid otitis media	0.378	0.622
D50.8 Other iron deficiency anaemias	0.378	0.622
E05.9 Thyrotoxicosis, unspecified	0.379	0.621
B99 Other and unspecified infectious diseases	0.380	0.620
D59 Acquired haemolytic anaemia	0.380	0.620
F42 Obsessive-compulsive disorder	0.380	0.620
M60-M63 Disorders of muscles	0.381	0.619
E89.3 Postprocedural hypopituitarism	0.381	0.619
M91-M94 Chondropathies	0.384	0.616
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.385	0.615
E73.9 Lactose intolerance, unspecified	0.386	0.614
B34.4 Papovirus infection, unspecified	0.386	0.613
E05.5 Thyroid crisis or storm	0.387	0.613
E05.4 Thyrotoxicosis factitia	0.387	0.613
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.387	0.613
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.387	0.613
L29.8 Other pruritus	0.390	0.610
H65.1 Other acute nonsuppurative otitis media	0.391	0.609
H65.0 Acute serous otitis media	0.391	0.609
L29.9 Pruritus, unspecified	0.391	0.609
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.393	0.607
I21.9 Acute myocardial infarction, unspecified	0.393	0.607
D68.2 Hereditary deficiency of other clotting factors	0.394	0.606
E10.0 With coma	0.396	0.604
E27.4 Other and unspecified adrenocortical insufficiency	0.396	0.603
E10.7 With multiple complications	0.397	0.603
F70-F79 Mental retardation	0.397	0.603
H82 Vertiginous syndromes in diseases classified elsewhere	0.397	0.603
E87.4 Mixed disorder of acid-base balance	0.398	0.602
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.398	0.602
L30.8 Other specified dermatitis	0.399	0.601
M07.38 Other psoriatic arthropathies (Other)	0.400	0.600
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.400	0.600
M07.36 Other psoriatic arthropathies (Lower leg)	0.400	0.600
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.400	0.600
M07.34 Other psoriatic arthropathies (Hand)	0.400	0.600
M07.33 Other psoriatic arthropathies (Forearm)	0.400	0.600
M07.32 Other psoriatic arthropathies (Upper arm)	0.400	0.600
M07.31 Other psoriatic arthropathies (Shoulder region)	0.400	0.600
D84 Other immunodeficiencies	0.400	0.600
D83 Common variable immunodeficiency	0.400	0.600
D82 Immunodeficiency associated with other major defects	0.400	0.600
D81 Combined immunodeficiencies	0.400	0.600
H69 Other disorders of Eustachian tube	0.401	0.599
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.402	0.598
M95.8 Other specified acquired deformities of musculoskeletal system	0.402	0.598
M95.5 Acquired deformity of pelvis	0.402	0.598
M95.4 Acquired deformity of chest and rib	0.402	0.598
M95.3 Acquired deformity of neck	0.402	0.598
M95.2 Other acquired deformity of head	0.402	0.598
M95.1 Cauliflower ear	0.402	0.598
E89.2 Postprocedural hypoparathyroidism	0.402	0.598
D53 Other nutritional anaemias	0.403	0.597
I69 Sequelae of cerebrovascular disease	0.404	0.596
L08.8 Other specified local infections of skin and subcutaneous tissue	0.404	0.596
L29.3 Anogenital pruritus, unspecified	0.406	0.594
L29.1 Pruritus scroti	0.406	0.594
D68.4 Acquired coagulation factor deficiency	0.407	0.593
D68.1 Hereditary factor XI deficiency	0.407	0.593
M05.8 Other seropositive rheumatoid arthritis	0.409	0.591
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.409	0.591
M05.2 Rheumatoid vasculitis	0.409	0.591
M05.1 Rheumatoid lung disease	0.409	0.591
M05.0 Felty's syndrome	0.409	0.591
F81 Specific developmental disorders of scholastic skills	0.409	0.591
M30 Polyarteritis nodosa and related conditions	0.410	0.590
L43 Lichen planus	0.410	0.590
M34.9 Systemic sclerosis, unspecified	0.410	0.590
L42 Pityriasis rosea	0.410	0.589
I73 Other peripheral vascular diseases	0.413	0.587
L27.0 Generalised skin eruption due to drugs and medicaments	0.414	0.586
F05 Delirium, not induced by alcohol and other psychoactive substances	0.415	0.585
M35.9 Systemic involvement of connective tissue, unspecified	0.415	0.585
M35.8 Other specified systemic involvement of connective tissue	0.415	0.585
M35.6 Relapsing panniculitis [Weber-Christian]	0.415	0.585
M35.5 Multifocal fibrosclerosis	0.415	0.585
M35.4 Diffuse (eosinophilic) fasciitis	0.415	0.585
M35.2 Behcet's disease	0.415	0.585
M35.1 Other overlap syndromes	0.415	0.585
E83 Disorders of mineral metabolism	0.415	0.585
L08.1 Erythrasma	0.416	0.584
L08.0 Pyoderma	0.416	0.584
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.416	0.584
F43 Reaction to severe stress, and adjustment disorders	0.417	0.583
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.417	0.583
M32 Systemic lupus erythematosus	0.417	0.583
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.418	0.582
I21.2 Acute transmural myocardial infarction of other sites	0.418	0.582
I05-I09 Chronic rheumatic heart diseases	0.418	0.582
M22 Disorders of patella	0.419	0.581
M46.9 Inflammatory spondylopathy, unspecified	0.419	0.581
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions	0.420	0.580
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases	0.420	0.580
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms	0.420	0.580
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases	0.420	0.580
F20 Schizophrenia	0.421	0.579
H72.2 Other marginal perforations of tympanic membrane	0.424	0.576
B35.3 Tinea pedis	0.424	0.576
E35 Disorders of endocrine glands in diseases classified elsewhere	0.425	0.575
E32 Diseases of thymus	0.425	0.575
E31 Polyglandular dysfunction	0.425	0.575
E30 Disorders of puberty, not elsewhere classified	0.425	0.575
E25 Adrenogenital disorders	0.425	0.575
E20 Hypoparathyroidism	0.425	0.575
M00 Pyogenic arthritis	0.426	0.573
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.428	0.572
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.429	0.571
L40.0 Psoriasis vulgaris	0.430	0.570
I21.1 Acute transmural myocardial infarction of inferior wall	0.430	0.570
I77 Other disorders of arteries and arterioles	0.431	0.569
E14.9 Without complications	0.433	0.567
H72.8 Other perforations of tympanic membrane	0.434	0.566
E10.8 With unspecified complications	0.434	0.566
M06.08 Seronegative rheumatoid arthritis (Other)	0.435	0.565
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.435	0.565
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.435	0.565
M06.04 Seronegative rheumatoid arthritis (Hand)	0.435	0.565
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.435	0.565
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.435	0.565
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.435	0.565
F99-F99 Unspecified mental disorder	0.435	0.565
D64 Other anaemias	0.436	0.564
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.436	0.564
F42.9 Obsessive-compulsive disorder, unspecified	0.436	0.564
B37.3 Candidiasis of vulva and vagina	0.437	0.563
F30 Manic episode	0.438	0.562
I73.0 Raynaud's syndrome	0.438	0.562
H83.0 Labyrinthitis	0.438	0.562
B35.9 Dermatophytosis, unspecified	0.439	0.561
B35.8 Other dermatophytoses	0.439	0.561
B35.6 Tinea cruris	0.439	0.561
B35.5 Tinea imbricata	0.439	0.561
B35.4 Tinea corporis	0.439	0.561
B35.2 Tinea manuum	0.439	0.561
B35.0 Tinea barbae and tinea capitis	0.439	0.561
D68.6 Other Thrombophilia	0.440	0.560
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.440	0.560
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.442	0.558
M10 Gout	0.443	0.557
F22 Persistent delusional disorders	0.444	0.556
D86.3 Sarcoidosis of skin	0.444	0.555
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.444	0.555
D86.1 Sarcoidosis of lymph nodes	0.444	0.555
A80-A89 Viral infections of the central nervous system	0.446	0.554
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.447	0.553
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.447	0.553
E87.5 Hyperkalaemia	0.447	0.553
B95-B98 Bacterial, viral and other infectious agents	0.447	0.553
E26 Hyperaldosteronism	0.447	0.552
I63 Cerebral infarction	0.448	0.552
I22 Subsequent myocardial infarction	0.448	0.552
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.448	0.551
E27.5 Adrenomedullary hyperfunction	0.449	0.550
E27.3 Drug-induced adrenocortical insufficiency	0.449	0.550
E27.2 Addisonian crisis	0.449	0.550
E27.0 Other adrenocortical overactivity	0.449	0.550
F60 Specific personality disorders	0.450	0.550
F40 Phobic anxiety disorders	0.452	0.548
R21 Rash and other nonspecific skin eruption	0.452	0.548
F00 Dementia in Alzheimer's disease	0.454	0.546
D57 Sickle-cell disorders	0.454	0.546
D56 Thalassaemia	0.454	0.546
D55 Anaemia due to enzyme disorders	0.454	0.546
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.454	0.546
B49 Unspecified mycosis	0.455	0.545
E53 Deficiency of other B group vitamins	0.455	0.545
F25 Schizoaffective disorders	0.455	0.545
E80.4 Gilbert's syndrome	0.455	0.545
E87.3 Alkalosis	0.455	0.544
E73.8 Other lactose intolerance	0.456	0.544
E73.1 Secondary lactase deficiency	0.456	0.544
E73.0 Congenital lactase deficiency	0.456	0.544
M34.1 CR(E)ST syndrome	0.456	0.544
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.457	0.543
M33 Dermatopolymyositis	0.458	0.542
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.458	0.542
E10.6 With other specified complications	0.458	0.542
I67 Other cerebrovascular diseases	0.458	0.542
I69.3 Sequelae of cerebral infarction	0.459	0.541
E88.9 Metabolic disorder, unspecified	0.462	0.538
E88.8 Other specified metabolic disorders	0.462	0.538
E88.3 Tumour lysis syndrome	0.462	0.538
E88.1 Lipodystrophy, not elsewhere classified	0.462	0.538
I62 Other nontraumatic intracranial haemorrhage	0.463	0.537
D69.3 Idiopathic thrombocytopenic purpura	0.463	0.537
B25.9 Cytomegaloviral disease, unspecified	0.463	0.537
A59 Trichomoniasis	0.464	0.536

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations