TreeWAS – Variant ID: rs2523554

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
R31 Unspecified haematuria	0.000	0.000	1.000
G35 Multiple sclerosis	1.000	0.000	0.000
E05.0 Thyrotoxicosis with diffuse goitre	1.000	0.000	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
L40.9 Psoriasis, unspecified	0.000	0.002	0.998
E10-E14 Diabetes mellitus	0.997	0.003	0.000
E10 Insulin-dependent diabetes mellitus	0.997	0.003	0.000
L40 Psoriasis	0.000	0.006	0.994
D69.6 Thrombocytopenia, unspecified	0.993	0.007	0.000
D69 Purpura and other haemorrhagic conditions	0.993	0.007	0.000
E27.1 Primary adrenocortical insufficiency	0.993	0.007	0.000
E27 Other disorders of adrenal gland	0.991	0.009	0.000
E20-E35 Disorders of other endocrine glands	0.990	0.010	0.000
L40.5 Arthropathic psoriasis	0.000	0.010	0.990
D80-D89 Certain disorders involving the immune mechanism	0.989	0.011	0.000
D86 Sarcoidosis	0.988	0.012	0.000
D86.9 Sarcoidosis, unspecified	0.988	0.012	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.987	0.013	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.985	0.015	0.000
E03 Other hypothyroidism	0.984	0.016	0.000
E03.9 Hypothyroidism, unspecified	0.975	0.025	0.000
E10.9 Without complications	0.971	0.029	0.000
E10.3 With ophthalmic complications	0.963	0.037	0.000
K90 Intestinal malabsorption	0.962	0.038	0.000
D80 Immunodeficiency with predominantly antibody defects	0.936	0.064	0.000
E50-E64 Other nutritional deficiencies	0.934	0.066	0.000
K90.9 Intestinal malabsorption, unspecified	0.930	0.070	0.000
E10.1 With ketoacidosis	0.915	0.085	0.000
E10.2 With renal complications	0.909	0.091	0.000
E53 Deficiency of other B group vitamins	0.906	0.094	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.892	0.108	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.889	0.111	0.000
M35.0 Sicca syndrome [Sjogren]	0.884	0.116	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.884	0.116	0.000
D55-D59 Haemolytic anaemias	0.882	0.118	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.879	0.121	0.000
E53.8 Deficiency of other specified B group vitamins	0.873	0.127	0.000
L40.0 Psoriasis vulgaris	0.000	0.129	0.871
E27.4 Other and unspecified adrenocortical insufficiency	0.865	0.135	0.000
E27.2 Addisonian crisis	0.851	0.149	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.845	0.155	0.000
L40.8 Other psoriasis	0.000	0.156	0.844
D59 Acquired haemolytic anaemia	0.840	0.160	0.000
D69.5 Secondary thrombocytopenia	0.839	0.161	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.831	0.169	0.000
E20 Hypoparathyroidism	0.827	0.173	0.000
D86.1 Sarcoidosis of lymph nodes	0.811	0.188	0.000
D69.4 Other primary thrombocytopenia	0.803	0.197	0.000
D69.9 Haemorrhagic condition, unspecified	0.802	0.198	0.000
D69.8 Other specified haemorrhagic conditions	0.798	0.202	0.000
M45 Ankylosing spondylitis	0.000	0.202	0.797
D69.2 Other nonthrombocytopenic purpura	0.792	0.208	0.000
M35 Other systemic involvement of connective tissue	0.789	0.211	0.000
E06 Thyroiditis	0.788	0.212	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.788	0.212	0.000
F41.2 Mixed anxiety and depressive disorder	0.000	0.214	0.786
E10.7 With multiple complications	0.778	0.222	0.000
D83 Common variable immunodeficiency	0.777	0.223	0.000
E31 Polyglandular dysfunction	0.777	0.223	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.771	0.229	0.000
M35.3 Polymyalgia rheumatica	0.763	0.237	0.000
E10.5 With peripheral circulatory complications	0.761	0.239	0.000
F41 Other anxiety disorders	0.000	0.241	0.759
E10.6 With other specified complications	0.758	0.242	0.000
E53.9 Vitamin B deficiency, unspecified	0.751	0.249	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.747	0.253	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.254	0.746
D59.9 Acquired haemolytic anaemia, unspecified	0.744	0.256	0.000
D86.3 Sarcoidosis of skin	0.744	0.256	0.000
E14 Unspecified diabetes mellitus	0.743	0.257	0.000
E25 Adrenogenital disorders	0.735	0.265	0.000
D59.1 Other autoimmune haemolytic anaemias	0.735	0.265	0.000
E16 Other disorders of pancreatic internal secretion	0.734	0.266	0.000
D66 Hereditary factor VIII deficiency	0.729	0.271	0.000
F41.9 Anxiety disorder, unspecified	0.000	0.273	0.727
D86.8 Sarcoidosis of other and combined sites	0.726	0.274	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.000	0.276	0.724
E10.8 With unspecified complications	0.722	0.278	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.715	0.285	0.000
F30-F39 Mood [affective] disorders	0.000	0.286	0.714
L40.4 Guttate psoriasis	0.000	0.287	0.713
L40.2 Acrodermatitis continua	0.000	0.287	0.713
E27.5 Adrenomedullary hyperfunction	0.711	0.289	0.000
E27.0 Other adrenocortical overactivity	0.711	0.289	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.710	0.290	0.000
E32 Diseases of thymus	0.710	0.290	0.000
E30 Disorders of puberty, not elsewhere classified	0.710	0.290	0.000
D81 Combined immunodeficiencies	0.709	0.290	0.000
E20.9 Hypoparathyroidism, unspecified	0.709	0.291	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.709	0.291	0.000
E34 Other endocrine disorders	0.708	0.292	0.000
K90.8 Other intestinal malabsorption	0.708	0.292	0.000
E10.0 With coma	0.708	0.292	0.000
E63 Other nutritional deficiencies	0.706	0.294	0.000
E03.5 Myxoedema coma	0.705	0.295	0.000
E03.4 Atrophy of thyroid (acquired)	0.705	0.295	0.000
E03.3 Postinfectious hypothyroidism	0.705	0.295	0.000
E03.8 Other specified hypothyroidism	0.704	0.296	0.000
E03.1 Congenital hypothyroidism without goitre	0.703	0.297	0.000
Chapter V Mental and behavioural disorders	0.000	0.299	0.701
L40.1 Generalised pustular psoriasis	0.000	0.302	0.698
F30 Manic episode	0.000	0.304	0.696
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.695	0.305	0.000
D82 Immunodeficiency associated with other major defects	0.693	0.307	0.000
E51 Thiamine deficiency	0.691	0.309	0.000
D69.1 Qualitative platelet defects	0.690	0.309	0.000
E06.3 Autoimmune thyroiditis	0.691	0.309	0.000
K90.3 Pancreatic steatorrhoea	0.690	0.310	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.690	0.310	0.000
K90.1 Tropical sprue	0.690	0.310	0.000
E14.3 With ophthalmic complications	0.688	0.312	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.687	0.313	0.000
F31 Bipolar affective disorder	0.000	0.314	0.686
F32 Depressive episode	0.000	0.315	0.685
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.684	0.315	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.684	0.316	0.000
E55 Vitamin D deficiency	0.684	0.316	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.680	0.320	0.000
E07 Other disorders of thyroid	0.680	0.320	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.680	0.320	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.680	0.320	0.000
E22 Hyperfunction of pituitary gland	0.679	0.321	0.000
F30.0 Hypomania	0.000	0.324	0.676
E13 Other specified diabetes mellitus	0.673	0.327	0.000
F32.9 Depressive episode, unspecified	0.000	0.328	0.672
D80.8 Other immunodeficiencies with predominantly antibody defects	0.671	0.329	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.671	0.329	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.671	0.329	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.671	0.329	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.671	0.329	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.670	0.330	0.000
E50 Vitamin A deficiency	0.670	0.330	0.000
E60 Dietary zinc deficiency	0.670	0.330	0.000
E59 Dietary selenium deficiency	0.670	0.330	0.000
E54 Ascorbic acid deficiency	0.670	0.330	0.000
E52 Niacin deficiency [pellagra]	0.670	0.330	0.000
E78.0 Pure hypercholesterolaemia	0.000	0.332	0.668
D84 Other immunodeficiencies	0.665	0.335	0.000
E16.2 Hypoglycaemia, unspecified	0.663	0.337	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.655	0.344	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.345	0.655
D59.4 Other nonautoimmune haemolytic anaemias	0.652	0.348	0.000
E53.1 Pyridoxine deficiency	0.649	0.350	0.000
E53.0 Riboflavin deficiency	0.649	0.350	0.000
F44 Dissociative [conversion] disorders	0.000	0.352	0.648
D50-D53 Nutritional anaemias	0.646	0.353	0.000
E27.8 Other specified disorders of adrenal gland	0.642	0.358	0.000
E40-E46 Malnutrition	0.641	0.359	0.000
E24 Cushing's syndrome	0.640	0.360	0.000
D89.3 Immune reconstitution syndrome	0.639	0.360	0.000
D55 Anaemia due to enzyme disorders	0.632	0.368	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.632	0.368	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.631	0.369	0.000
E05.8 Other thyrotoxicosis	0.630	0.370	0.000
E56 Other vitamin deficiencies	0.627	0.373	0.000
F60-F69 Disorders of adult personality and behaviour	0.000	0.373	0.626
D83.9 Common variable immunodeficiency, unspecified	0.625	0.375	0.000
L40.3 Pustulosis palmaris et plantaris	0.000	0.375	0.625
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.376	0.624
E31.0 Autoimmune polyglandular failure	0.624	0.376	0.000
F48 Other neurotic disorders	0.000	0.378	0.622
E58 Dietary calcium deficiency	0.615	0.384	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.615	0.385	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.386	0.614
M35.7 Hypermobility syndrome	0.612	0.388	0.000
D67 Hereditary factor IX deficiency	0.611	0.389	0.000
E15 Nondiabetic hypoglycaemic coma	0.606	0.394	0.000
E07.8 Other specified disorders of thyroid	0.604	0.396	0.000
E34.9 Endocrine disorder, unspecified	0.604	0.396	0.000
D59.8 Other acquired haemolytic anaemias	0.603	0.397	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.603	0.397	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.603	0.397	0.000
D59.3 Haemolytic-uraemic syndrome	0.603	0.397	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.603	0.397	0.000
D57 Sickle-cell disorders	0.602	0.398	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.399	0.601
F60 Specific personality disorders	0.000	0.400	0.600
D89.1 Cryoglobulinaemia	0.599	0.401	0.000
D58 Other hereditary haemolytic anaemias	0.599	0.401	0.000
E14.2 Withrenal complications	0.593	0.407	0.000
E20.8 Other hypoparathyroidism	0.593	0.407	0.000
E20.1 Pseudohypoparathyroidism	0.593	0.407	0.000
E20.0 Idiopathic hypoparathyroidism	0.593	0.407	0.000
D68 Other coagulation defects	0.588	0.412	0.000
M35.8 Other specified systemic involvement of connective tissue	0.584	0.415	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.576	0.424	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.428	0.572
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.428	0.572
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.428	0.572
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.428	0.572
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.428	0.572
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.428	0.572
D51 Vitamin B12 deficiency anaemia	0.571	0.429	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.430	0.570
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.430	0.570
F43 Reaction to severe stress, and adjustment disorders	0.000	0.433	0.567
M35.9 Systemic involvement of connective tissue, unspecified	0.565	0.434	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.565	0.434	0.000
M35.5 Multifocal fibrosclerosis	0.565	0.434	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.565	0.434	0.000
E06.4 Drug-induced thyroiditis	0.565	0.435	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.565	0.435	0.000
E06.1 Subacute thyroiditis	0.565	0.435	0.000
E06.0 Acute thyroiditis	0.565	0.435	0.000
E14.5 With peripheral circulatory complications	0.565	0.435	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.561	0.439	0.000
C91 Lymphoid leukaemia	0.561	0.439	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.000	0.442	0.558
D83.8 Other common variable immunodeficiencies	0.557	0.442	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.557	0.442	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.557	0.442	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.557	0.442	0.000
F30.9 Manic episode, unspecified	0.000	0.443	0.557
E31.9 Polyglandular dysfunction, unspecified	0.557	0.443	0.000
E31.8 Other polyglandular dysfunction	0.557	0.443	0.000
E31.1 Polyglandular hyperfunction	0.557	0.443	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.557	0.443	0.000
F44.5 Dissociative convulsions	0.000	0.443	0.557
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.447	0.553
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.552	0.448	0.000
M35.1 Other overlap syndromes	0.552	0.448	0.000
F32.8 Other depressive episodes	0.000	0.449	0.551
C91.1 Chronic lymphocytic leukaemia	0.551	0.449	0.000
D69.0 Allergic purpura	0.548	0.451	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.000	0.452	0.548
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.456	0.544
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.543	0.456	0.000
E63.9 Nutritional deficiency, unspecified	0.542	0.457	0.000
E14.6 With other specified complications	0.541	0.459	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.540	0.460	0.000
C83.0 Small cell (diffuse)	0.538	0.462	0.000
F06.7 Mild cognitive disorder	0.000	0.464	0.536
E06.9 Thyroiditis, unspecified	0.533	0.467	0.000
E14.7 With multiple complications	0.533	0.467	0.000
E14.0 With coma	0.533	0.467	0.000
D56 Thalassaemia	0.529	0.471	0.000
F30.2 Mania with psychotic symptoms	0.000	0.472	0.528
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.527	0.473	0.000
E14.1 With ketoacidosis	0.527	0.473	0.000
E25.9 Adrenogenital disorder, unspecified	0.527	0.473	0.000
E25.8 Other adrenogenital disorders	0.527	0.473	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.527	0.473	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.527	0.473	0.000
E16.4 Abnormal secretion of gastrin	0.527	0.473	0.000
E16.3 Increased secretion of glucagon	0.527	0.473	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.522	0.478	0.000
C92 Myeloid leukaemia	0.522	0.478	0.000
E22.1 Hyperprolactinaemia	0.518	0.481	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.482	0.518
E51.2 Wernicke's encephalopathy	0.517	0.483	0.000
E13.3 With ophthalmic complications	0.514	0.486	0.000
C91.0 Acute lymphoblastic leukaemia	0.514	0.486	0.000
F48.0 Neurasthenia	0.000	0.486	0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.514	0.486	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.514	0.486	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.514	0.486	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.514	0.486	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.514	0.486	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.514	0.486	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.514	0.486	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.514	0.486	0.000
E61 Deficiency of other nutrient elements	0.514	0.486	0.000
E12.9 Without complications	0.513	0.487	0.000
E12.8 With unspecified complications	0.513	0.487	0.000
E12.7 With multiple complications	0.513	0.487	0.000
E12.6 With other specified complications	0.513	0.487	0.000
E12.5 With peripheral circulatory complications	0.513	0.487	0.000
E12.4 With neurological complications	0.513	0.487	0.000
E12.3 With ophthalmic complications	0.513	0.487	0.000
E12.2 With renal complications	0.513	0.487	0.000
E12.1 With ketoacidosis	0.513	0.487	0.000
E12.0 With coma	0.513	0.487	0.000
F70-F79 Mental retardation	0.000	0.489	0.511
E26 Hyperaldosteronism	0.511	0.489	0.000
E30.9 Disorder of puberty, unspecified	0.509	0.491	0.000
E30.8 Other disorders of puberty	0.509	0.491	0.000
E30.1 Precocious puberty	0.509	0.491	0.000
E30.0 Delayed puberty	0.509	0.491	0.000
E32.9 Disease of thymus, unspecified	0.509	0.491	0.000
E32.8 Other diseases of thymus	0.509	0.491	0.000
E32.1 Abscess of thymus	0.509	0.491	0.000
E32.0 Persistent hyperplasia of thymus	0.509	0.491	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.509	0.491	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.509	0.491	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.509	0.491	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.491	0.509
D81.9 Combined immunodeficiency, unspecified	0.509	0.491	0.000
D81.8 Other combined immunodeficiencies	0.509	0.491	0.000
D81.7 Major histocompatibility complex class II deficiency	0.509	0.491	0.000
D81.6 Major histocompatibility complex class I deficiency	0.509	0.491	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.509	0.491	0.000
D81.4 Nezelof's syndrome	0.509	0.491	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.509	0.491	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.509	0.491	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.509	0.491	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.509	0.491	0.000
E34.5 Androgen resistance syndrome	0.508	0.492	0.000
E34.4 Constitutional tall stature	0.508	0.492	0.000
E34.3 Short stature, not elsewhere classified	0.508	0.492	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.508	0.492	0.000
E34.1 Other hypersecretion of intestinal hormones	0.508	0.492	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.508	0.492	0.000
F60.3 Emotionally unstable personality disorder	0.000	0.493	0.507
E28 Ovarian dysfunction	0.506	0.493	0.001
F34 Persistent mood [affective] disorders	0.000	0.493	0.507
E63.8 Other specified nutritional deficiencies	0.506	0.494	0.000
E63.1 Imbalance of constituents of food intake	0.506	0.494	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.506	0.494	0.000
E55.9 Vitamin D deficiency, unspecified	0.505	0.495	0.000
D53 Other nutritional anaemias	0.503	0.497	0.000
F48.9 Neurotic disorder, unspecified	0.000	0.497	0.503
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.497	0.503
L40-L45 Papulosquamous disorders	0.004	0.498	0.498
E34.8 Other specified endocrine disorders	0.501	0.499	0.000
E29 Testicular dysfunction	0.500	0.499	0.000
F30.8 Other manic episodes	0.000	0.501	0.499
F41.3 Other mixed anxiety disorders	0.000	0.501	0.499
D82.9 Immunodeficiency associated with major defect, unspecified	0.497	0.503	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.497	0.503	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.497	0.503	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.497	0.503	0.000
D82.2 Immunodeficiency with short-limbed stature	0.497	0.503	0.000
D82.0 Wiskott-Aldrich syndrome	0.497	0.503	0.000
E51.9 Thiamine deficiency, unspecified	0.495	0.504	0.000
E51.8 Other manifestations of thiamine deficiency	0.495	0.504	0.000
E51.1 Beriberi	0.495	0.504	0.000
E24.0 Pituitary-dependent Cushing's disease	0.494	0.506	0.000
D84.1 Defects in the complement system	0.493	0.507	0.000
E14.8 With unspecified complications	0.491	0.509	0.000
F60.9 Personality disorder, unspecified	0.000	0.509	0.491
E55.0 Rickets, active	0.491	0.509	0.000
F99-F99 Unspecified mental disorder	0.000	0.509	0.491
C88 Malignant immunoproliferative diseases	0.490	0.510	0.000
E07.1 Dyshormogenetic goitre	0.488	0.512	0.000
E07.0 Hypersecretion of calcitonin	0.488	0.512	0.000
E22.8 Other hyperfunction of pituitary gland	0.487	0.513	0.000
F30.1 Mania without psychotic symptoms	0.000	0.513	0.487
F60.7 Dependent personality disorder	0.000	0.513	0.487
E06.5 Other chronic thyroiditis	0.486	0.514	0.000
F38 Other mood [affective] disorders	0.000	0.515	0.485
E24.8 Other Cushing's syndrome	0.484	0.516	0.000
C92.0 Acute myeloid leukaemia	0.484	0.516	0.000
E13.8 With unspecified complications	0.482	0.517	0.000
E13.7 With multiple complications	0.482	0.517	0.000
E13.6 With other specified complications	0.482	0.517	0.000
E13.5 With peripheral circulatory complications	0.482	0.517	0.000
E13.4 With neurological complications	0.482	0.517	0.000
E13.2 With renal complications	0.482	0.517	0.000
E13.1 With ketoacidosis	0.482	0.517	0.000
E13.0 With coma	0.482	0.517	0.000
F44.4 Dissociative motor disorders	0.000	0.519	0.480
E50.9 Vitamin A deficiency, unspecified	0.480	0.520	0.000
E50.8 Other manifestations of vitamin A deficiency	0.480	0.520	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.480	0.520	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.480	0.520	0.000
E50.5 Vitamin A deficiency with night blindness	0.480	0.520	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.480	0.520	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.480	0.520	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.480	0.520	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.480	0.520	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.480	0.520	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.480	0.520	0.000
E64.8 Sequelae of other nutritional deficiencies	0.480	0.520	0.000
E64.3 Sequelae of rickets	0.480	0.520	0.000
E64.2 Sequelae of vitamin C deficiency	0.480	0.520	0.000
E64.1 Sequelae of vitamin A deficiency	0.480	0.520	0.000
E64.0 Sequelae of protein-energy malnutrition	0.480	0.520	0.000
D82.1 Di George's syndrome	0.480	0.520	0.000
F60.5 Anankastic personality disorder	0.000	0.522	0.478
F60.8 Other specific personality disorders	0.000	0.522	0.478
C84 Peripheral and cutaneous T-cell lymphomas	0.478	0.522	0.000
F31.8 Other bipolar affective disorders	0.000	0.523	0.477
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.477	0.523	0.000
C90.2 Plasmacytoma, extramedullary	0.477	0.523	0.000
E10.4 With neurological complications	0.476	0.524	0.000
F33 Recurrent depressive disorder	0.000	0.524	0.476
C91.4 Hairy-cell leukaemia	0.473	0.527	0.000
F60.6 Anxious [avoidant] personality disorder	0.000	0.528	0.472
D84.8 Other specified immunodeficiencies	0.471	0.529	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.000	0.533	0.467
F41.8 Other specified anxiety disorders	0.000	0.535	0.465
F44.7 Mixed dissociative [conversion] disorders	0.000	0.536	0.464
F44.6 Dissociative anaesthesia and sensory loss	0.000	0.536	0.464
F44.3 Trance and possession disorders	0.000	0.536	0.464
F44.2 Dissociative stupor	0.000	0.536	0.464
F44.1 Dissociative fugue	0.000	0.536	0.464
F39 Unspecified mood [affective] disorder	0.000	0.536	0.464
C93 Monocytic leukaemia	0.464	0.536	0.000
F43.0 Acute stress reaction	0.000	0.537	0.463
E24.2 Drug-induced Cushing's syndrome	0.460	0.540	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.460	0.540	0.000
E45 Retarded development following protein-energy malnutrition	0.460	0.540	0.000
E43 Unspecified severe protein-energy malnutrition	0.460	0.540	0.000
E42 Marasmic kwashiorkor	0.460	0.540	0.000
E41 Nutritional marasmus	0.460	0.540	0.000
E40 Kwashiorkor	0.460	0.540	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.459	0.541	0.000
E24.3 Ectopic ACTH syndrome	0.459	0.541	0.000
E24.1 Nelson's syndrome	0.459	0.541	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.453	0.547	0.000
D55.8 Other anaemias due to enzyme disorders	0.453	0.547	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.453	0.547	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.453	0.547	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.453	0.547	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.453	0.547	0.000
F02 Dementia in other diseases classified elsewhere	0.000	0.549	0.451
C94 Other leukaemias of specified cell type	0.451	0.549	0.000
D68.9 Coagulation defect, unspecified	0.451	0.549	0.000
F44.8 Other dissociative [conversion] disorders	0.000	0.550	0.450
E56.9 Vitamin deficiency, unspecified	0.449	0.550	0.000
E56.8 Deficiency of other vitamins	0.449	0.550	0.000
E56.0 Deficiency of vitamin E	0.449	0.550	0.000
F68 Other disorders of adult personality and behaviour	0.000	0.551	0.449
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.000	0.551	0.449
F65 Disorders of sexual preference	0.000	0.551	0.449
F63 Habit and impulse disorders	0.000	0.551	0.449
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.448	0.552	0.000
F61 Mixed and other personality disorders	0.000	0.553	0.447
F48.8 Other specified neurotic disorders	0.000	0.554	0.446
F48.1 Depersonalisation-derealisation syndrome	0.000	0.554	0.446
D51.8 Other vitamin B12 deficiency anaemias	0.443	0.557	0.000
F44.0 Dissociative amnesia	0.000	0.560	0.440
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.440	0.560	0.000
F43.2 Adjustment disorders	0.000	0.562	0.438
C88.0 Waldenstrom's macroglobulinaemia	0.436	0.564	0.000
D58.0 Hereditary spherocytosis	0.435	0.565	0.000
E14.4 With neurological complications	0.432	0.568	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.000	0.568	0.432
D57.8 Other sickle-cell disorders	0.432	0.568	0.000
D57.3 Sickle-cell trait	0.432	0.568	0.000
D57.2 Double heterozygous sickling disorders	0.432	0.568	0.000
D57.0 Sickle-cell anaemia with crisis	0.432	0.568	0.000
E16.1 Other hypoglycaemia	0.431	0.568	0.000
F60.4 Histrionic personality disorder	0.000	0.569	0.430
F60.1 Schizoid personality disorder	0.000	0.569	0.430
D58.8 Other specified hereditary haemolytic anaemias	0.429	0.570	0.000
D58.1 Hereditary elliptocytosis	0.429	0.570	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.429	0.571	0.000
E65-E68 Obesity and other hyperalimentation	0.428	0.571	0.000
M35.2 Behcet's disease	0.428	0.572	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.575	0.425
D68.5 Primary Thrombophilia	0.425	0.575	0.000
L42 Pityriasis rosea	0.002	0.578	0.420
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.000	0.578	0.422
D68.1 Hereditary factor XI deficiency	0.419	0.580	0.000
D84.9 Immunodeficiency, unspecified	0.419	0.581	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.000	0.582	0.418
F60.2 Dissocial personality disorder	0.000	0.583	0.416
E22.0 Acromegaly and pituitary gigantism	0.416	0.584	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.585	0.415
F43.9 Reaction to severe stress, unspecified	0.000	0.585	0.415
G35-G37 Demyelinating diseases of the central nervous system	0.415	0.585	0.000
D86.0 Sarcoidosis of lung	0.414	0.586	0.000
F09 Unspecified organic or symptomatic mental disorder	0.000	0.589	0.411
C95 Leukaemia of unspecified cell type	0.411	0.589	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.410	0.590	0.000
D51.2 Transcobalamin II deficiency	0.409	0.591	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.409	0.591	0.000
F60.0 Paranoid personality disorder	0.000	0.591	0.409
C85.7 Other specified types of non-Hodgkin's lymphoma	0.409	0.591	0.000
C92.7 Other myeloid leukaemia	0.408	0.592	0.000
D68.6 Other Thrombophilia	0.408	0.592	0.000
F43.8 Other reactions to severe stress	0.000	0.593	0.407
E56.1 Deficiency of vitamin K	0.406	0.593	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.405	0.594	0.000
C92.9 Myeloid leukaemia, unspecified	0.405	0.595	0.000
C86 Other specified types of T/NK-cell lymphoma	0.404	0.596	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.403	0.597	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.403	0.597	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.402	0.598	0.000
C91.7 Other lymphoid leukaemia	0.402	0.598	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.402	0.598	0.000
C91.3 Prolymphocytic leukaemia	0.402	0.598	0.000
C91.2 Subacute lymphocytic leukaemia	0.402	0.598	0.000
D57.1 Sickle-cell anaemia without crisis	0.402	0.598	0.000
D53.9 Nutritional anaemia, unspecified	0.401	0.599	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.000	0.600	0.400
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.602	0.398
C92.4 Acute promyelocytic leukaemia	0.395	0.605	0.000
C93.1 Chronic monocytic leukaemia	0.394	0.606	0.000
C91.9 Lymphoid leukaemia, unspecified	0.394	0.606	0.000
C92.5 Acute myelomonocytic leukaemia	0.394	0.606	0.000
E13.9 Without complications	0.393	0.606	0.000
E28.3 Primary ovarian failure	0.391	0.609	0.000
C84.4 Peripheral T-cell lymphoma	0.391	0.609	0.000
D58.2 Other haemoglobinopathies	0.391	0.609	0.000
F00 Dementia in Alzheimer's disease	0.000	0.610	0.390
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.610	0.390
F06.6 Organic emotionally labile [asthenic] disorder	0.000	0.610	0.390
F06.5 Organic dissociative disorder	0.000	0.610	0.390

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations