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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2523638
log Bayes Factor = 102.446
Chromosome 6   position 31,344,273  (GRCh37) Explore rs2523638 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E14.9 Without complications
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E20-E35 Disorders of other endocrine glands
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
E10.1 With ketoacidosis
0.000 0.001 0.999
E05.9 Thyrotoxicosis, unspecified
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.001 0.999
E27 Other disorders of adrenal gland
0.000 0.001 0.999
E03.9 Hypothyroidism, unspecified
0.000 0.001 0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.000 0.002 0.998
E16.2 Hypoglycaemia, unspecified
0.000 0.002 0.998
E27.1 Primary adrenocortical insufficiency
0.000 0.005 0.995
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.005 0.995
E11.9 Without complications
0.000 0.005 0.995
E10.4 With neurological complications
0.000 0.012 0.988
K51 Ulcerative colitis
0.988 0.012 0.000
M45 Ankylosing spondylitis
0.986 0.014 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.983 0.017 0.000
E11.3 With ophthalmic complications
0.000 0.017 0.983
K51.9 Ulcerative colitis, unspecified
0.981 0.019 0.000
J45.9 Asthma, unspecified
0.000 0.031 0.969
K51.3 Ulcerative (chronic) rectosigmoiditis
0.965 0.035 0.000
K51.2 Ulcerative (chronic) proctitis
0.965 0.035 0.000
K51.4 Pseudopolyposis of colon
0.947 0.053 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.054 0.946
E11.1 With ketoacidosis
0.000 0.055 0.945
E10.0 With coma
0.000 0.065 0.935
E11.5 With peripheral circulatory complications
0.000 0.070 0.930
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.071 0.929
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.071 0.929
E22 Hyperfunction of pituitary gland
0.000 0.072 0.928
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.081 0.919
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.094 0.906
E23 Hypofunction and other disorders of pituitary gland
0.000 0.105 0.895
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.109 0.891
E10.8 With unspecified complications
0.000 0.112 0.888
E10.2 With renal complications
0.000 0.118 0.882
K50-K52 Noninfective enteritis and colitis
0.875 0.125 0.001
K51.5 Mucosal proctocolitis
0.865 0.135 0.000
K50 Crohn's disease [regional enteritis]
0.865 0.135 0.000
E11.0 With coma
0.000 0.144 0.856
E10.5 With peripheral circulatory complications
0.000 0.146 0.854
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.152 0.848
E22.0 Acromegaly and pituitary gigantism
0.000 0.152 0.848
K50.9 Crohn's disease, unspecified
0.847 0.153 0.000
E14.1 With ketoacidosis
0.000 0.155 0.845
E07 Other disorders of thyroid
0.000 0.156 0.844
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.159 0.841
E27.9 Disorder of adrenal gland, unspecified
0.000 0.160 0.840
E14.8 With unspecified complications
0.000 0.177 0.823
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.194 0.806
E23.2 Diabetes insipidus
0.000 0.195 0.805
E10.6 With other specified complications
0.000 0.196 0.804
K51.8 Other ulcerative colitis
0.800 0.200 0.000
E14.3 With ophthalmic complications
0.000 0.212 0.788
E28 Ovarian dysfunction
0.000 0.215 0.785
E14.6 With other specified complications
0.000 0.217 0.783
E23.7 Disorder of pituitary gland, unspecified
0.000 0.220 0.780
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.221 0.779
E20 Hypoparathyroidism
0.000 0.224 0.776
K50.0 Crohn's disease of small intestine
0.772 0.228 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.771 0.228 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.233 0.767
E07.8 Other specified disorders of thyroid
0.000 0.238 0.762
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.240 0.760
E10.7 With multiple complications
0.000 0.241 0.759
E40-E46 Malnutrition
0.000 0.250 0.750
E06 Thyroiditis
0.000 0.256 0.744
E25 Adrenogenital disorders
0.000 0.267 0.733
D64.9 Anaemia, unspecified
0.000 0.270 0.730
M45.X6 Ankylosing spondylitis (Lumbar region)
0.730 0.270 0.000
E14.5 With peripheral circulatory complications
0.000 0.272 0.728
M06 Other rheumatoid arthritis
0.000 0.272 0.727
H36.0 Diabetic retinopathy
0.000 0.276 0.724
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.283 0.717
E32 Diseases of thymus
0.000 0.283 0.717
E30 Disorders of puberty, not elsewhere classified
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
E27.5 Adrenomedullary hyperfunction
0.000 0.284 0.716
E27.0 Other adrenocortical overactivity
0.000 0.284 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
E31 Polyglandular dysfunction
0.000 0.289 0.711
E27.2 Addisonian crisis
0.000 0.290 0.710
E14.2 Withrenal complications
0.000 0.290 0.710
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.707 0.293 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.707 0.293 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.707 0.293 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.707 0.293 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.707 0.293 0.000
E13 Other specified diabetes mellitus
0.000 0.296 0.704
M06.3 Rheumatoid nodule
0.000 0.298 0.702
E34 Other endocrine disorders
0.000 0.300 0.700
K90 Intestinal malabsorption
0.000 0.300 0.700
K50.1 Crohn's disease of large intestine
0.699 0.301 0.000
E23.6 Other disorders of pituitary gland
0.000 0.301 0.699
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.304 0.696
E16.1 Other hypoglycaemia
0.000 0.305 0.695
E24 Cushing's syndrome
0.000 0.329 0.671
E14.4 With neurological complications
0.000 0.334 0.666
E22.8 Other hyperfunction of pituitary gland
0.000 0.334 0.666
E26 Hyperaldosteronism
0.000 0.337 0.663
E22.1 Hyperprolactinaemia
0.000 0.338 0.662
M45.X2 Ankylosing spondylitis (Cervical region)
0.661 0.338 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.340 0.660
E11.2 With renal complications
0.000 0.342 0.658
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.344 0.656
E05.8 Other thyrotoxicosis
0.000 0.345 0.655
E11.6 With other specified complications
0.000 0.356 0.644
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.358 0.642
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.358 0.642
E06.3 Autoimmune thyroiditis
0.000 0.358 0.642
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.358 0.641
E23.1 Drug-induced hypopituitarism
0.000 0.358 0.641
E03.8 Other specified hypothyroidism
0.000 0.359 0.641
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.360 0.640
E27.8 Other specified disorders of adrenal gland
0.000 0.360 0.640
M06.34 Rheumatoid nodule (Hand)
0.000 0.369 0.631
E29 Testicular dysfunction
0.000 0.369 0.631
E28.2 Polycystic ovarian syndrome
0.000 0.383 0.617
E20.9 Hypoparathyroidism, unspecified
0.000 0.384 0.616
K51.1 Ulcerative (chronic) ileocolitis
0.610 0.390 0.000
E11.8 With unspecified complications
0.000 0.392 0.608
E07.1 Dyshormogenetic goitre
0.000 0.395 0.605
E07.0 Hypersecretion of calcitonin
0.000 0.395 0.605
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.399 0.601
E28.3 Primary ovarian failure
0.000 0.418 0.582
K90.9 Intestinal malabsorption, unspecified
0.000 0.419 0.581
K90.8 Other intestinal malabsorption
0.000 0.423 0.577
E46 Unspecified protein-energy malnutrition
0.000 0.428 0.572
E21.3 Hyperparathyroidism, unspecified
0.000 0.430 0.570
E11.4 With neurological complications
0.000 0.432 0.568
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.433 0.567
E28.9 Ovarian dysfunction, unspecified
0.000 0.437 0.563
E28.8 Other ovarian dysfunction
0.000 0.437 0.563
E28.1 Androgen excess
0.000 0.437 0.563
E28.0 Oestrogen excess
0.000 0.437 0.563
E34.9 Endocrine disorder, unspecified
0.000 0.439 0.561
E20.8 Other hypoparathyroidism
0.000 0.443 0.557
E20.1 Pseudohypoparathyroidism
0.000 0.443 0.557
E20.0 Idiopathic hypoparathyroidism
0.000 0.443 0.557
M06.8 Other specified rheumatoid arthritis
0.000 0.456 0.544
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.458 0.542
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.462 0.538
E45 Retarded development following protein-energy malnutrition
0.000 0.462 0.538
E43 Unspecified severe protein-energy malnutrition
0.000 0.462 0.538
E42 Marasmic kwashiorkor
0.000 0.462 0.538
E41 Nutritional marasmus
0.000 0.462 0.538
E40 Kwashiorkor
0.000 0.462 0.538
E24.0 Pituitary-dependent Cushing's disease
0.000 0.465 0.535
E06.4 Drug-induced thyroiditis
0.000 0.467 0.533
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.467 0.533
E06.0 Acute thyroiditis
0.000 0.467 0.533
E21.4 Other specified disorders of parathyroid gland
0.000 0.471 0.529
K51.0 Ulcerative (chronic) enterocolitis
0.528 0.472 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.474 0.526
E25.8 Other adrenogenital disorders
0.000 0.474 0.526
E06.1 Subacute thyroiditis
0.000 0.474 0.525
M06.2 Rheumatoid bursitis
0.000 0.478 0.522
M06.1 Adult-onset Still's disease
0.000 0.478 0.522
E07.9 Disorder of thyroid, unspecified
0.000 0.482 0.518
E26.9 Hyperaldosteronism, unspecified
0.000 0.483 0.516
E06.5 Other chronic thyroiditis
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E30.9 Disorder of puberty, unspecified
0.000 0.486 0.514
E30.8 Other disorders of puberty
0.000 0.486 0.514
E30.1 Precocious puberty
0.000 0.486 0.514
E30.0 Delayed puberty
0.000 0.486 0.514
E32.9 Disease of thymus, unspecified
0.000 0.486 0.514
E32.8 Other diseases of thymus
0.000 0.486 0.514
E32.1 Abscess of thymus
0.000 0.486 0.514
E32.0 Persistent hyperplasia of thymus
0.000 0.486 0.514
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.486 0.514
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.486 0.514
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.486 0.514
E31.9 Polyglandular dysfunction, unspecified
0.000 0.490 0.510
E31.8 Other polyglandular dysfunction
0.000 0.490 0.510
E31.1 Polyglandular hyperfunction
0.000 0.490 0.510
E13.9 Without complications
0.000 0.492 0.508
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.492 0.508
E34.8 Other specified endocrine disorders
0.000 0.493 0.507
G35 Multiple sclerosis
0.506 0.494 0.000
E13.8 With unspecified complications
0.000 0.495 0.505
E13.7 With multiple complications
0.000 0.495 0.505
E13.6 With other specified complications
0.000 0.495 0.505
E13.5 With peripheral circulatory complications
0.000 0.495 0.505
E13.4 With neurological complications
0.000 0.495 0.505
E13.2 With renal complications
0.000 0.495 0.505
E13.1 With ketoacidosis
0.000 0.495 0.505
E13.0 With coma
0.000 0.495 0.505
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.495 0.505
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.496 0.504
E31.0 Autoimmune polyglandular failure
0.000 0.496 0.504
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.497 0.503
M06.38 Rheumatoid nodule (Other)
0.000 0.497 0.503
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.497 0.503
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.497 0.503
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.497 0.503
E34.5 Androgen resistance syndrome
0.000 0.498 0.502
E34.4 Constitutional tall stature
0.000 0.498 0.502
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.498 0.502
E34.1 Other hypersecretion of intestinal hormones
0.000 0.498 0.502
K90.3 Pancreatic steatorrhoea
0.000 0.498 0.502
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.498 0.502
K90.1 Tropical sprue
0.000 0.498 0.502
E24.2 Drug-induced Cushing's syndrome
0.000 0.503 0.497
E13.3 With ophthalmic complications
0.000 0.511 0.489
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.519 0.481
E24.3 Ectopic ACTH syndrome
0.000 0.519 0.481
E24.1 Nelson's syndrome
0.000 0.519 0.481
E26.8 Other hyperaldosteronism
0.000 0.524 0.476
E26.1 Secondary hyperaldosteronism
0.000 0.524 0.476
E24.8 Other Cushing's syndrome
0.000 0.524 0.476
E21.0 Primary hyperparathyroidism
0.000 0.527 0.473
K50.8 Other Crohn's disease
0.463 0.537 0.000
K75.4 Autoimmune hepatitis
0.000 0.545 0.455
E34.3 Short stature, not elsewhere classified
0.000 0.546 0.454
E29.8 Other testicular dysfunction
0.000 0.547 0.452
E29.0 Testicular hyperfunction
0.000 0.547 0.452
E34.0 Carcinoid syndrome
0.000 0.554 0.446
E21.2 Other hyperparathyroidism
0.000 0.555 0.444
K75 Other inflammatory liver diseases
0.000 0.558 0.442
M06.33 Rheumatoid nodule (Forearm)
0.000 0.559 0.441
K70-K77 Diseases of liver
0.000 0.569 0.431
M06.4 Inflammatory polyarthropathy
0.000 0.569 0.431
K74 Fibrosis and cirrhosis of liver
0.000 0.570 0.430
E29.9 Testicular dysfunction, unspecified
0.000 0.570 0.430
K73 Chronic hepatitis, not elsewhere classified
0.000 0.584 0.416
K74.3 Primary biliary cirrhosis
0.000 0.585 0.415
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.587 0.413
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.592 0.408
E06.9 Thyroiditis, unspecified
0.000 0.594 0.406
G35-G37 Demyelinating diseases of the central nervous system
0.405 0.595 0.000
K75.8 Other specified inflammatory liver diseases
0.000 0.603 0.397
D64 Other anaemias
0.000 0.603 0.397
E29.1 Testicular hypofunction
0.000 0.604 0.396
K73.9 Chronic hepatitis, unspecified
0.000 0.607 0.393
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.610 0.390
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.610 0.390
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.610 0.390
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.610 0.390
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.610 0.390
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.610 0.390
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.610 0.390
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.610 0.390
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.610 0.390
H36 Retinal disorders in diseases classified elsewhere
0.000 0.610 0.390
K74.5 Biliary cirrhosis, unspecified
0.000 0.612 0.388
E65-E68 Obesity and other hyperalimentation
0.000 0.613 0.387
E44.1 Mild protein-energy malnutrition
0.000 0.614 0.386
E44.0 Moderate protein-energy malnutrition
0.000 0.614 0.386
G37 Other demyelinating diseases of central nervous system
0.384 0.616 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.626 0.374
M06.18 Adult-onset Still's disease (Other)
0.000 0.626 0.374
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.626 0.374
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.626 0.374
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.626 0.374
M06.14 Adult-onset Still's disease (Hand)
0.000 0.626 0.374
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.626 0.374
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.626 0.374
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.626 0.374
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.626 0.374
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.626 0.374
M06.28 Rheumatoid bursitis (Other)
0.000 0.626 0.374
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.626 0.374
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.626 0.374
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.626 0.374
M06.24 Rheumatoid bursitis (Hand)
0.000 0.626 0.374
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.626 0.374
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.626 0.374
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.626 0.374
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.626 0.374
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.629 0.371
K74.6 Other and unspecified cirrhosis of liver
0.000 0.631 0.369
G37.9 Demyelinating disease of central nervous system, unspecified
0.366 0.634 0.000
K72 Hepatic failure, not elsewhere classified
0.000 0.644 0.356
E26.0 Primary hyperaldosteronism
0.000 0.645 0.355
E50-E64 Other nutritional deficiencies
0.000 0.648 0.351
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.651 0.349
J45 Asthma
0.000 0.660 0.340
K71 Toxic liver disease
0.000 0.676 0.324
E24.9 Cushing's syndrome, unspecified
0.000 0.678 0.321
H20.9 Iridocyclitis, unspecified
0.320 0.680 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.681 0.319
K72.9 Hepatic failure, unspecified
0.000 0.681 0.319
K74.1 Hepatic sclerosis
0.000 0.682 0.318
K75.2 Nonspecific reactive hepatitis
0.000 0.683 0.317
K75.1 Phlebitis of portal vein
0.000 0.683 0.317
K52 Other non-infective gastro-enteritis and colitis
0.316 0.684 0.001
K77 Liver disorders in diseases classified elsewhere
0.000 0.691 0.309
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.691 0.309
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.691 0.309
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.691 0.309
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.691 0.309
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.691 0.309
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.691 0.309
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.691 0.309
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.309 0.691 0.000
K74.4 Secondary biliary cirrhosis
0.000 0.691 0.309
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.691 0.309
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.693 0.306
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.304 0.696 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.701 0.299
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.701 0.299
G36 Other acute disseminated demyelination
0.298 0.702 0.000
K74.0 Hepatic fibrosis
0.000 0.705 0.295
E23.0 Hypopituitarism
0.000 0.708 0.291
I83 Varicose veins of lower extremities
0.289 0.711 0.000
D64.4 Congenital dyserythropoietic anaemia
0.000 0.715 0.284
D64.3 Other sideroblastic anaemias
0.000 0.715 0.284
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.715 0.284
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.715 0.284
D64.0 Hereditary sideroblastic anaemia
0.000 0.717 0.283
M05-M14 Inflammatory polyarthropathies
0.000 0.717 0.283
I83.0 Varicose veins of lower extremities with ulcer
0.280 0.720 0.000
E51 Thiamine deficiency
0.000 0.720 0.280
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.720 0.280
M05 Seropositive rheumatoid arthritis
0.000 0.722 0.278
E67 Other hyperalimentation
0.000 0.723 0.277
E68 Sequelae of hyperalimentation
0.000 0.723 0.277
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.723 0.277
G37.5 Concentric sclerosis [Balo]
0.275 0.724 0.000
G37.4 Subacute necrotising myelitis
0.275 0.724 0.000
G37.2 Central pontine myelinolysis
0.275 0.724 0.000
G37.1 Central demyelination of corpus callosum
0.275 0.724 0.000
G37.0 Diffuse sclerosis
0.275 0.724 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.725 0.275
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.727 0.273
K52.3 Indeterminate colitis
0.269 0.731 0.000
K72.1 Chronic hepatic failure
0.000 0.737 0.263
K71.0 Toxic liver disease with cholestasis
0.000 0.740 0.260
H20 Iridocyclitis
0.256 0.744 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.255 0.745 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.254 0.746 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.748 0.252
E63 Other nutritional deficiencies
0.000 0.748 0.252
E50 Vitamin A deficiency
0.000 0.748 0.252
E60 Dietary zinc deficiency
0.000 0.748 0.252
E59 Dietary selenium deficiency
0.000 0.748 0.252
E54 Ascorbic acid deficiency
0.000 0.748 0.252
E52 Niacin deficiency [pellagra]
0.000 0.748 0.252
J45.1 Nonallergic asthma
0.000 0.748 0.252
E58 Dietary calcium deficiency
0.000 0.749 0.251
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.750 0.250
G37.8 Other specified demyelinating diseases of central nervous system
0.250 0.750 0.000
J45.8 Mixed asthma
0.000 0.755 0.245
E56 Other vitamin deficiencies
0.000 0.760 0.240
E70-E90 Metabolic disorders
0.001 0.761 0.238
D64.8 Other specified anaemias
0.000 0.762 0.238
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.766 0.233
K71.8 Toxic liver disease with other disorders of liver
0.000 0.767 0.232
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.767 0.232
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.767 0.232
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.767 0.232
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.767 0.232
K71.2 Toxic liver disease with acute hepatitis
0.000 0.767 0.232
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.232 0.768 0.001
D60-D64 Aplastic and other anaemias
0.000 0.771 0.229
E65 Localised adiposity
0.000 0.771 0.229
E51.2 Wernicke's encephalopathy
0.000 0.771 0.229
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.775 0.225
I83.1 Varicose veins of lower extremities with inflammation
0.223 0.777 0.000
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.778 0.222
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.778 0.222
G36.0 Neuromyelitis optica [Devic]
0.222 0.778 0.000
K71.9 Toxic liver disease, unspecified
0.000 0.778 0.222
H20.0 Acute and subacute iridocyclitis
0.222 0.778 0.000
K75.0 Abscess of liver
0.000 0.779 0.221
D62 Acute posthaemorrhagic anaemia
0.000 0.781 0.219
K52.1 Toxic gastro-enteritis and colitis
0.219 0.781 0.000
E74 Other disorders of carbohydrate metabolism
0.001 0.783 0.216
G36.9 Acute disseminated demyelination, unspecified
0.214 0.786 0.000
G36.8 Other specified acute disseminated demyelination
0.214 0.786 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.214 0.786 0.000
M05.8 Other seropositive rheumatoid arthritis
0.000 0.789 0.211
H20.8 Other iridocyclitis
0.211 0.789 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.793 0.207
M14 Arthropathies in other diseases classified elsewhere
0.000 0.793 0.207
M12 Other specific arthropathies
0.000 0.794 0.206
K75.9 Inflammatory liver disease, unspecified
0.000 0.794 0.206
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.795 0.204
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.796 0.204
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.797 0.203
K72.0 Acute and subacute hepatic failure
0.000 0.798 0.202
E51.9 Thiamine deficiency, unspecified
0.000 0.799 0.201
E51.8 Other manifestations of thiamine deficiency
0.000 0.799 0.201
E51.1 Beriberi
0.000 0.799 0.201
J45.0 Predominantly allergic asthma
0.000 0.800 0.200
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.800 0.199
M05.1 Rheumatoid lung disease
0.000 0.800 0.199
M05.0 Felty's syndrome
0.000 0.800 0.199
E67.8 Other specified hyperalimentation
0.000 0.801 0.199
E67.3 Hypervitaminosis D
0.000 0.801 0.199
E67.2 Megavitamin-B6 syndrome
0.000 0.801 0.199
E67.1 Hypercarotenaemia
0.000 0.801 0.199
E67.0 Hypervitaminosis A
0.000 0.801 0.199
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.801 0.199
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.801 0.199
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.801 0.199
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.801 0.199
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.801 0.199
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.804 0.196
H20.1 Chronic iridocyclitis
0.196 0.804 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.805 0.195
E78.2 Mixed hyperlipidaemia
0.000 0.805 0.195
E61 Deficiency of other nutrient elements
0.000 0.806 0.194
E55 Vitamin D deficiency
0.000 0.808 0.192
M08 Juvenile arthritis
0.000 0.811 0.188
E89.3 Postprocedural hypopituitarism
0.000 0.816 0.184
H20.2 Lens-induced iridocyclitis
0.184 0.816 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.819 0.181
E50.8 Other manifestations of vitamin A deficiency
0.000 0.819 0.181
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.819 0.181
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.819 0.181
E50.5 Vitamin A deficiency with night blindness
0.000 0.819 0.181
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.819 0.181
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.819 0.181
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.819 0.181
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.819 0.181
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.819 0.181
E63.9 Nutritional deficiency, unspecified
0.000 0.819 0.181
E63.8 Other specified nutritional deficiencies
0.000 0.819 0.181
E63.1 Imbalance of constituents of food intake
0.000 0.819 0.181
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.819 0.181
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.819 0.181
E64.8 Sequelae of other nutritional deficiencies
0.000 0.819 0.181
E64.3 Sequelae of rickets
0.000 0.819 0.181
E64.2 Sequelae of vitamin C deficiency
0.000 0.819 0.181
E64.1 Sequelae of vitamin A deficiency
0.000 0.819 0.181
E64.0 Sequelae of protein-energy malnutrition
0.000 0.819 0.181
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.820 0.180
M10 Gout
0.000 0.820 0.180
E79 Disorders of purine and pyrimidine metabolism
0.001 0.822 0.177
E78.8 Other disorders of lipoprotein metabolism
0.000 0.823 0.177
M06.0 Seronegative rheumatoid arthritis
0.001 0.825 0.174
E56.9 Vitamin deficiency, unspecified
0.000 0.828 0.172
E56.8 Deficiency of other vitamins
0.000 0.828 0.172
E56.0 Deficiency of vitamin E
0.000 0.828 0.172
E77 Disorders of glycoprotein metabolism
0.001 0.829 0.170
E76 Disorders of glycosaminoglycan metabolism
0.001 0.829 0.170
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.829 0.170
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.829 0.170
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.829 0.171
E78.1 Pure hyperglyceridaemia
0.000 0.830 0.170
E84 Cystic fibrosis
0.001 0.830 0.169
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.836 0.164
E70 Disorders of aromatic amino-acid metabolism
0.001 0.836 0.163
E78.6 Lipoprotein deficiency
0.000 0.836 0.164
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.837 0.162
E73 Lactose intolerance
0.001 0.838 0.161
M05.2 Rheumatoid vasculitis
0.000 0.838 0.161
E56.1 Deficiency of vitamin K
0.000 0.840 0.159
E83 Disorders of mineral metabolism
0.129 0.842 0.029

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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