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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2523685
log Bayes Factor = 5.57605
Chromosome 6   position 31,426,256  (GRCh37) Explore rs2523685 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E10.9 Without complications
0.000 0.130 0.870
E10 Insulin-dependent diabetes mellitus
0.000 0.163 0.837
E10.3 With ophthalmic complications
0.000 0.223 0.777
E10.1 With ketoacidosis
0.000 0.264 0.736
E10.0 With coma
0.000 0.297 0.703
K90 Intestinal malabsorption
0.000 0.343 0.657
E10.5 With peripheral circulatory complications
0.000 0.358 0.642
E10.8 With unspecified complications
0.000 0.384 0.615
E10.2 With renal complications
0.000 0.385 0.614
E10.7 With multiple complications
0.000 0.400 0.600
E10.4 With neurological complications
0.000 0.421 0.578
E10.6 With other specified complications
0.000 0.455 0.545
K90.8 Other intestinal malabsorption
0.000 0.474 0.526
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.502 0.498
K90.3 Pancreatic steatorrhoea
0.000 0.529 0.471
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.529 0.471
K90.1 Tropical sprue
0.000 0.529 0.471
E10-E14 Diabetes mellitus
0.000 0.564 0.436
K90.9 Intestinal malabsorption, unspecified
0.000 0.595 0.405
E11 Non-insulin-dependent diabetes mellitus
0.000 0.634 0.366
K90-K93 Other diseases of the digestive system
0.000 0.646 0.354
E11.3 With ophthalmic complications
0.000 0.649 0.351
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.664 0.336
E13 Other specified diabetes mellitus
0.000 0.679 0.321
E12 Malnutrition-related diabetes mellitus
0.000 0.687 0.313
E11.2 With renal complications
0.000 0.700 0.300
K91.3 Postoperative intestinal obstruction
0.000 0.702 0.298
E11.8 With unspecified complications
0.000 0.707 0.293
E11.1 With ketoacidosis
0.000 0.721 0.279
E11.5 With peripheral circulatory complications
0.000 0.728 0.272
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.729 0.271
E11.4 With neurological complications
0.000 0.733 0.267
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.733 0.267
E14 Unspecified diabetes mellitus
0.000 0.734 0.266
E11.7 With multiple complications
0.000 0.738 0.262
K91.5 Postcholecystectomy syndrome
0.000 0.738 0.262
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.739 0.261
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.746 0.254
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.753 0.247
K91.4 Colostomy and enterostomy malfunction
0.000 0.755 0.245
E13.9 Without complications
0.000 0.761 0.239
E13.8 With unspecified complications
0.000 0.769 0.230
E13.7 With multiple complications
0.000 0.769 0.230
E13.6 With other specified complications
0.000 0.769 0.230
E13.5 With peripheral circulatory complications
0.000 0.769 0.230
E13.4 With neurological complications
0.000 0.769 0.230
E13.3 With ophthalmic complications
0.000 0.769 0.230
E13.2 With renal complications
0.000 0.769 0.230
E13.1 With ketoacidosis
0.000 0.769 0.230
E13.0 With coma
0.000 0.769 0.230
E12.9 Without complications
0.000 0.775 0.224
E12.8 With unspecified complications
0.000 0.775 0.224
E12.7 With multiple complications
0.000 0.775 0.224
E12.6 With other specified complications
0.000 0.775 0.224
E12.5 With peripheral circulatory complications
0.000 0.775 0.224
E12.4 With neurological complications
0.000 0.775 0.224
E12.3 With ophthalmic complications
0.000 0.775 0.224
E12.2 With renal complications
0.000 0.775 0.224
E12.1 With ketoacidosis
0.000 0.775 0.224
E12.0 With coma
0.000 0.775 0.224
K91.1 Postgastric surgery syndromes
0.000 0.779 0.221
E11.0 With coma
0.000 0.794 0.205
E14.8 With unspecified complications
0.000 0.799 0.201
E14.4 With neurological complications
0.000 0.808 0.192
E14.7 With multiple complications
0.000 0.809 0.191
E14.6 With other specified complications
0.000 0.809 0.191
E14.0 With coma
0.000 0.809 0.191
E14.5 With peripheral circulatory complications
0.000 0.811 0.189
E14.2 Withrenal complications
0.000 0.812 0.188
E14.9 Without complications
0.000 0.815 0.185
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.818 0.182
K93.1 Megacolon in Chagas' disease
0.000 0.818 0.182
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.818 0.182
E14.1 With ketoacidosis
0.000 0.826 0.174
E11.6 With other specified complications
0.000 0.832 0.167
E14.3 With ophthalmic complications
0.000 0.834 0.166
R31 Unspecified haematuria
0.080 0.920 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.072 0.928 0.000
C79 Secondary malignant neoplasm of other sites
0.000 0.928 0.072
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.000 0.930 0.070
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.000 0.932 0.068
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.000 0.932 0.068
C77.1 Intrathoracic lymph nodes
0.000 0.932 0.068
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.000 0.933 0.067
C78.0 Secondary malignant neoplasm of lung
0.000 0.933 0.067
C79.9 Secondary malignant neoplasm, unspecified site
0.000 0.936 0.064
C79.2 Secondary malignant neoplasm of skin
0.000 0.938 0.062
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.062 0.938 0.000
C79.6 Secondary malignant neoplasm of ovary
0.000 0.938 0.062
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.000 0.938 0.062
C78.7 Secondary malignant neoplasm of liver
0.000 0.941 0.059
D86.9 Sarcoidosis, unspecified
0.000 0.942 0.058
C77.9 Lymph node, unspecified
0.000 0.943 0.057
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.000 0.943 0.057
D86 Sarcoidosis
0.000 0.944 0.056
C79.7 Secondary malignant neoplasm of adrenal gland
0.000 0.945 0.055
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.000 0.946 0.054
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.000 0.946 0.054
E27.1 Primary adrenocortical insufficiency
0.000 0.946 0.054
C82.1 Mixed small cleaved and large cell, follicular
0.054 0.946 0.000
D86.1 Sarcoidosis of lymph nodes
0.000 0.946 0.054
C82.3 Follicular lymphoma grade IIIa
0.053 0.947 0.000
C82.0 Small cleaved cell, follicular
0.051 0.949 0.000
C82.4 Follicular lymphoma grade IIIb
0.050 0.950 0.000
C77.8 Lymph nodes of multiple regions
0.000 0.950 0.050
C76 Malignant neoplasm of other and ill-defined sites
0.000 0.952 0.048
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.952 0.048
E27 Other disorders of adrenal gland
0.000 0.952 0.048
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.048 0.952 0.000
D80-D89 Certain disorders involving the immune mechanism
0.000 0.955 0.045
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.955 0.045
C82.6 Cutaneous follicle centre lymphoma
0.045 0.955 0.000
C82.5 Diffuse follicle centre lymphoma
0.045 0.955 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.000 0.955 0.045
J31.0 Chronic rhinitis
0.045 0.955 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.957 0.043
E20-E35 Disorders of other endocrine glands
0.000 0.957 0.043
C82.2 Large cell, follicular
0.043 0.957 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.000 0.958 0.042
C78.4 Secondary malignant neoplasm of small intestine
0.000 0.958 0.042
C80 Malignant neoplasm without specification of site
0.000 0.958 0.042
E27.2 Addisonian crisis
0.000 0.959 0.041
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.000 0.959 0.041
E16.2 Hypoglycaemia, unspecified
0.000 0.959 0.041
D50 Iron deficiency anaemia
0.000 0.959 0.041
D50.9 Iron deficiency anaemia, unspecified
0.000 0.959 0.041
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.959 0.041
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.960 0.040
D50.8 Other iron deficiency anaemias
0.000 0.960 0.040
D86.3 Sarcoidosis of skin
0.000 0.960 0.040
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.960 0.040
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.960 0.040
C76.0 Head, face and neck
0.000 0.960 0.040
D50-D53 Nutritional anaemias
0.000 0.962 0.038
D68 Other coagulation defects
0.000 0.962 0.038
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.000 0.962 0.037
D86.0 Sarcoidosis of lung
0.000 0.963 0.037
D69 Purpura and other haemorrhagic conditions
0.000 0.963 0.037
D86.8 Sarcoidosis of other and combined sites
0.000 0.963 0.037
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.000 0.964 0.036
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.964 0.036
E20 Hypoparathyroidism
0.000 0.965 0.035
D68.0 Von Willebrand's disease
0.000 0.965 0.035
C76.8 Overlapping lesion of other and ill-defined sites
0.000 0.965 0.035
C76.7 Other ill-defined sites
0.000 0.965 0.035
C76.5 Lower limb
0.000 0.965 0.035
C76.4 Upper limb
0.000 0.965 0.035
D80 Immunodeficiency with predominantly antibody defects
0.000 0.965 0.035
E27.5 Adrenomedullary hyperfunction
0.000 0.965 0.035
E27.0 Other adrenocortical overactivity
0.000 0.965 0.035
C76.1 Thorax
0.000 0.965 0.034
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.966 0.034
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.966 0.034
D81 Combined immunodeficiencies
0.000 0.967 0.033
E15 Nondiabetic hypoglycaemic coma
0.000 0.967 0.032
D83 Common variable immunodeficiency
0.000 0.967 0.032
E22 Hyperfunction of pituitary gland
0.000 0.968 0.032
C76.2 Abdomen
0.000 0.968 0.032
E27.9 Disorder of adrenal gland, unspecified
0.000 0.968 0.032
C78.2 Secondary malignant neoplasm of pleura
0.000 0.968 0.032
D84 Other immunodeficiencies
0.000 0.968 0.032
D55-D59 Haemolytic anaemias
0.000 0.968 0.032
D82 Immunodeficiency associated with other major defects
0.000 0.969 0.031
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.969 0.031
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.969 0.031
E16.4 Abnormal secretion of gastrin
0.000 0.969 0.031
E16.3 Increased secretion of glucagon
0.000 0.969 0.031
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.969 0.031
E32 Diseases of thymus
0.000 0.969 0.031
E31 Polyglandular dysfunction
0.000 0.969 0.031
E30 Disorders of puberty, not elsewhere classified
0.000 0.969 0.031
E25 Adrenogenital disorders
0.000 0.969 0.031
C80.9 Malignant neoplasm, unspecified
0.000 0.969 0.031
C76.3 Pelvis
0.000 0.969 0.031
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.969 0.030
D68.2 Hereditary deficiency of other clotting factors
0.000 0.970 0.030
C77.2 Intra-abdominal lymph nodes
0.000 0.970 0.030
E23 Hypofunction and other disorders of pituitary gland
0.000 0.970 0.030
D68.5 Primary Thrombophilia
0.000 0.970 0.030
D69.5 Secondary thrombocytopenia
0.000 0.970 0.030
E20.9 Hypoparathyroidism, unspecified
0.000 0.970 0.030
D60-D64 Aplastic and other anaemias
0.000 0.970 0.030
D50.1 Sideropenic dysphagia
0.000 0.970 0.030
D69.4 Other primary thrombocytopenia
0.000 0.971 0.029
D59 Acquired haemolytic anaemia
0.000 0.971 0.029
C77.3 Axillary and upper limb lymph nodes
0.000 0.971 0.029
E27.8 Other specified disorders of adrenal gland
0.000 0.971 0.029
D66 Hereditary factor VIII deficiency
0.000 0.971 0.029
E50-E64 Other nutritional deficiencies
0.000 0.971 0.029
E16.1 Other hypoglycaemia
0.000 0.971 0.029
E40-E46 Malnutrition
0.000 0.971 0.029
D69.0 Allergic purpura
0.000 0.972 0.028
D64 Other anaemias
0.000 0.972 0.028
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.972 0.028
E34 Other endocrine disorders
0.000 0.972 0.028
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.972 0.028
D69.6 Thrombocytopenia, unspecified
0.000 0.972 0.028
D64.9 Anaemia, unspecified
0.000 0.973 0.027
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.973 0.027
D68.4 Acquired coagulation factor deficiency
0.000 0.973 0.027
D69.8 Other specified haemorrhagic conditions
0.000 0.973 0.027
D69.2 Other nonthrombocytopenic purpura
0.000 0.973 0.027
D69.1 Qualitative platelet defects
0.000 0.973 0.027
D59.1 Other autoimmune haemolytic anaemias
0.000 0.973 0.027
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.974 0.026
E28 Ovarian dysfunction
0.000 0.974 0.026
D53 Other nutritional anaemias
0.000 0.974 0.026
E20.8 Other hypoparathyroidism
0.000 0.974 0.025
E20.1 Pseudohypoparathyroidism
0.000 0.974 0.025
E20.0 Idiopathic hypoparathyroidism
0.000 0.974 0.025
M45 Ankylosing spondylitis
0.000 0.974 0.026
E23.6 Other disorders of pituitary gland
0.000 0.975 0.025
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.975 0.025
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.975 0.025
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.975 0.025
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.975 0.025
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.975 0.025
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.975 0.025
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.975 0.025
D68.9 Coagulation defect, unspecified
0.000 0.975 0.025
D68.6 Other Thrombophilia
0.000 0.975 0.025
D68.1 Hereditary factor XI deficiency
0.000 0.975 0.025
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.975 0.025
E22.0 Acromegaly and pituitary gigantism
0.000 0.975 0.025
E53 Deficiency of other B group vitamins
0.000 0.976 0.024
E23.7 Disorder of pituitary gland, unspecified
0.000 0.976 0.024
E22.1 Hyperprolactinaemia
0.000 0.976 0.024
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.976 0.024
D81.9 Combined immunodeficiency, unspecified
0.000 0.976 0.024
D81.8 Other combined immunodeficiencies
0.000 0.976 0.024
D81.7 Major histocompatibility complex class II deficiency
0.000 0.976 0.024
D81.6 Major histocompatibility complex class I deficiency
0.000 0.976 0.024
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.976 0.024
D81.4 Nezelof's syndrome
0.000 0.976 0.024
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.976 0.024
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.976 0.024
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.976 0.024
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.976 0.024
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.976 0.024
D83.8 Other common variable immunodeficiencies
0.000 0.976 0.023
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.976 0.023
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.976 0.023
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.976 0.023
E26 Hyperaldosteronism
0.000 0.976 0.023
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.000 0.976 0.023
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.977 0.023
E22.8 Other hyperfunction of pituitary gland
0.000 0.977 0.023
E29 Testicular dysfunction
0.000 0.977 0.023
D83.9 Common variable immunodeficiency, unspecified
0.000 0.977 0.023
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.977 0.023
D84.8 Other specified immunodeficiencies
0.000 0.977 0.023
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.977 0.023
D67 Hereditary factor IX deficiency
0.000 0.977 0.023
D84.9 Immunodeficiency, unspecified
0.000 0.977 0.023
D55 Anaemia due to enzyme disorders
0.000 0.977 0.023
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.977 0.022
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.977 0.022
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.977 0.022
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.977 0.022
D82.2 Immunodeficiency with short-limbed stature
0.000 0.977 0.022
D82.0 Wiskott-Aldrich syndrome
0.000 0.977 0.022
C77.4 Inguinal and lower limb lymph nodes
0.000 0.977 0.022
E25.9 Adrenogenital disorder, unspecified
0.000 0.977 0.022
E25.8 Other adrenogenital disorders
0.000 0.977 0.022
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.977 0.022
E30.9 Disorder of puberty, unspecified
0.000 0.977 0.022
E30.8 Other disorders of puberty
0.000 0.977 0.022
E30.1 Precocious puberty
0.000 0.977 0.022
E30.0 Delayed puberty
0.000 0.977 0.022
E31.9 Polyglandular dysfunction, unspecified
0.000 0.977 0.022
E31.8 Other polyglandular dysfunction
0.000 0.977 0.022
E31.1 Polyglandular hyperfunction
0.000 0.977 0.022
E31.0 Autoimmune polyglandular failure
0.000 0.977 0.022
E32.9 Disease of thymus, unspecified
0.000 0.977 0.022
E32.8 Other diseases of thymus
0.000 0.977 0.022
E32.1 Abscess of thymus
0.000 0.977 0.022
E32.0 Persistent hyperplasia of thymus
0.000 0.977 0.022
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.977 0.022
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.977 0.022
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.977 0.022
D84.1 Defects in the complement system
0.000 0.977 0.022
E24 Cushing's syndrome
0.000 0.977 0.022
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.978 0.022
K92 Other diseases of digestive system
0.000 0.978 0.022
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.978 0.022
E23.1 Drug-induced hypopituitarism
0.000 0.978 0.022
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.978 0.021
D56 Thalassaemia
0.000 0.979 0.021
D59.8 Other acquired haemolytic anaemias
0.000 0.979 0.021
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.979 0.021
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.979 0.021
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.979 0.021
D59.3 Haemolytic-uraemic syndrome
0.000 0.979 0.021
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.979 0.021
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.979 0.021
C80.0 Malignant neoplasm, primary site unknown, so stated
0.000 0.979 0.021
D57 Sickle-cell disorders
0.000 0.979 0.021
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.979 0.021
E63 Other nutritional deficiencies
0.000 0.979 0.021
E56 Other vitamin deficiencies
0.000 0.979 0.021
E51 Thiamine deficiency
0.000 0.979 0.021
E50 Vitamin A deficiency
0.000 0.979 0.021
E60 Dietary zinc deficiency
0.000 0.979 0.021
E59 Dietary selenium deficiency
0.000 0.979 0.021
E54 Ascorbic acid deficiency
0.000 0.979 0.021
E52 Niacin deficiency [pellagra]
0.000 0.979 0.021
D52 Folate deficiency anaemia
0.000 0.979 0.021
E34.9 Endocrine disorder, unspecified
0.000 0.979 0.021
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.979 0.021
E45 Retarded development following protein-energy malnutrition
0.000 0.979 0.021
E43 Unspecified severe protein-energy malnutrition
0.000 0.979 0.021
E42 Marasmic kwashiorkor
0.000 0.979 0.021
E41 Nutritional marasmus
0.000 0.979 0.021
E40 Kwashiorkor
0.000 0.979 0.021
D82.1 Di George's syndrome
0.000 0.979 0.021
E34.8 Other specified endocrine disorders
0.000 0.979 0.021
E53.8 Deficiency of other specified B group vitamins
0.000 0.979 0.021
D61 Other aplastic anaemias
0.000 0.979 0.021
E23.2 Diabetes insipidus
0.000 0.979 0.020
D64.4 Congenital dyserythropoietic anaemia
0.000 0.980 0.020
D64.3 Other sideroblastic anaemias
0.000 0.980 0.020
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.980 0.020
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.980 0.020
D64.0 Hereditary sideroblastic anaemia
0.000 0.980 0.020
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.980 0.020
C77.0 Lymph nodes of head, face and neck
0.000 0.980 0.020
E34.5 Androgen resistance syndrome
0.000 0.980 0.020
E34.4 Constitutional tall stature
0.000 0.980 0.020
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.980 0.020
E34.1 Other hypersecretion of intestinal hormones
0.000 0.980 0.020
E65-E68 Obesity and other hyperalimentation
0.000 0.980 0.020
E28.3 Primary ovarian failure
0.000 0.980 0.020
D64.8 Other specified anaemias
0.000 0.980 0.020
D69.9 Haemorrhagic condition, unspecified
0.000 0.980 0.020
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.981 0.019
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.981 0.019
D68.8 Other specified coagulation defects
0.000 0.981 0.019
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.981 0.019
D89.3 Immune reconstitution syndrome
0.000 0.981 0.019
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.981 0.019
D89.1 Cryoglobulinaemia
0.000 0.981 0.019
E34.0 Carcinoid syndrome
0.000 0.981 0.019
E28.9 Ovarian dysfunction, unspecified
0.000 0.981 0.019
E28.8 Other ovarian dysfunction
0.000 0.981 0.019
E28.1 Androgen excess
0.000 0.981 0.019
E28.0 Oestrogen excess
0.000 0.981 0.019
D53.8 Other specified nutritional anaemias
0.000 0.981 0.018
D53.2 Scorbutic anaemia
0.000 0.981 0.018
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.981 0.018
D53.0 Protein deficiency anaemia
0.000 0.981 0.018
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.981 0.018
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.981 0.018
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.981 0.018
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.981 0.018
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.981 0.018
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.981 0.018
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.981 0.018
E55 Vitamin D deficiency
0.000 0.982 0.018
E58 Dietary calcium deficiency
0.000 0.982 0.018
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.018 0.982 0.000
E11.9 Without complications
0.000 0.982 0.018
E53.9 Vitamin B deficiency, unspecified
0.000 0.982 0.018
E53.1 Pyridoxine deficiency
0.000 0.982 0.018
E53.0 Riboflavin deficiency
0.000 0.982 0.018
D58 Other hereditary haemolytic anaemias
0.000 0.982 0.017
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.982 0.018
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.983 0.017
E34.3 Short stature, not elsewhere classified
0.000 0.983 0.017
E26.8 Other hyperaldosteronism
0.000 0.983 0.017
E26.1 Secondary hyperaldosteronism
0.000 0.983 0.017
D51 Vitamin B12 deficiency anaemia
0.000 0.983 0.017
M06.9 Rheumatoid arthritis, unspecified
0.000 0.983 0.017
E29.9 Testicular dysfunction, unspecified
0.000 0.983 0.017
E29.8 Other testicular dysfunction
0.000 0.983 0.017
E29.0 Testicular hyperfunction
0.000 0.983 0.017
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.983 0.017
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.983 0.017
D55.8 Other anaemias due to enzyme disorders
0.000 0.983 0.017
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.983 0.017
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.983 0.017
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.983 0.017
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.983 0.017
E61 Deficiency of other nutrient elements
0.000 0.983 0.017
E24.2 Drug-induced Cushing's syndrome
0.000 0.983 0.017
D53.9 Nutritional anaemia, unspecified
0.000 0.983 0.016
E24.8 Other Cushing's syndrome
0.000 0.984 0.016
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.984 0.016
E24.3 Ectopic ACTH syndrome
0.000 0.984 0.016
E24.1 Nelson's syndrome
0.000 0.984 0.016
D18.0 Haemangioma, any site
0.016 0.984 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.984 0.016
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.984 0.016
D60.8 Other acquired pure red cell aplasias
0.000 0.984 0.016
D60.1 Transient acquired pure red cell aplasia
0.000 0.984 0.016
D60.0 Chronic acquired pure red cell aplasia
0.000 0.984 0.016
K92.8 Other specified diseases of digestive system
0.000 0.984 0.016
D56.9 Thalassaemia, unspecified
0.000 0.984 0.015
D56.8 Other thalassaemias
0.000 0.984 0.015
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.984 0.015
D56.2 Delta-beta thalassaemia
0.000 0.984 0.015
D56.0 Alpha thalassaemia
0.000 0.984 0.015
D61.9 Aplastic anaemia, unspecified
0.000 0.984 0.016
D57.8 Other sickle-cell disorders
0.000 0.984 0.015
D57.3 Sickle-cell trait
0.000 0.984 0.015
D57.2 Double heterozygous sickling disorders
0.000 0.984 0.015
D57.0 Sickle-cell anaemia with crisis
0.000 0.984 0.015
E50.9 Vitamin A deficiency, unspecified
0.000 0.985 0.015
E50.8 Other manifestations of vitamin A deficiency
0.000 0.985 0.015
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.985 0.015
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.985 0.015
E50.5 Vitamin A deficiency with night blindness
0.000 0.985 0.015
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.985 0.015
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.985 0.015
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.985 0.015
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.985 0.015
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.985 0.015
E51.9 Thiamine deficiency, unspecified
0.000 0.985 0.015
E51.8 Other manifestations of thiamine deficiency
0.000 0.985 0.015
E51.2 Wernicke's encephalopathy
0.000 0.985 0.015
E51.1 Beriberi
0.000 0.985 0.015
E56.9 Vitamin deficiency, unspecified
0.000 0.985 0.015
E56.8 Deficiency of other vitamins
0.000 0.985 0.015
E56.1 Deficiency of vitamin K
0.000 0.985 0.015
E56.0 Deficiency of vitamin E
0.000 0.985 0.015
E63.9 Nutritional deficiency, unspecified
0.000 0.985 0.015
E63.8 Other specified nutritional deficiencies
0.000 0.985 0.015
E63.1 Imbalance of constituents of food intake
0.000 0.985 0.015
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.985 0.015
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.985 0.015
E64.8 Sequelae of other nutritional deficiencies
0.000 0.985 0.015
E64.3 Sequelae of rickets
0.000 0.985 0.015
E64.2 Sequelae of vitamin C deficiency
0.000 0.985 0.015
E64.1 Sequelae of vitamin A deficiency
0.000 0.985 0.015
E64.0 Sequelae of protein-energy malnutrition
0.000 0.985 0.015
D52.8 Other folate deficiency anaemias
0.000 0.985 0.015
D52.1 Drug-induced folate deficiency anaemia
0.000 0.985 0.015
D52.0 Dietary folate deficiency anaemia
0.000 0.985 0.015
E44.1 Mild protein-energy malnutrition
0.000 0.985 0.015
E44.0 Moderate protein-energy malnutrition
0.000 0.985 0.015
E46 Unspecified protein-energy malnutrition
0.000 0.985 0.015
D56.1 Beta thalassaemia
0.000 0.985 0.015
D61.8 Other specified aplastic anaemias
0.000 0.985 0.015
D61.3 Idiopathic aplastic anaemia
0.000 0.985 0.015
D61.2 Aplastic anaemia due to other external agents
0.000 0.985 0.015
D61.1 Drug-induced aplastic anaemia
0.000 0.985 0.015
E67 Other hyperalimentation
0.000 0.985 0.015
E68 Sequelae of hyperalimentation
0.000 0.985 0.015
E26.9 Hyperaldosteronism, unspecified
0.000 0.985 0.014
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.985 0.015
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.985 0.014
J31.1 Chronic nasopharyngitis
0.014 0.986 0.000
D56.3 Thalassaemia trait
0.000 0.986 0.014
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.986 0.014
E21.3 Hyperparathyroidism, unspecified
0.000 0.986 0.014
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.986 0.014
D57.1 Sickle-cell anaemia without crisis
0.000 0.986 0.013
E24.0 Pituitary-dependent Cushing's disease
0.000 0.986 0.013
D62 Acute posthaemorrhagic anaemia
0.000 0.986 0.013
D61.0 Constitutional aplastic anaemia
0.000 0.987 0.013
E26.0 Primary hyperaldosteronism
0.000 0.987 0.013
E55.0 Rickets, active
0.000 0.987 0.013
E65 Localised adiposity
0.000 0.987 0.013
B37.8 Candidiasis of other sites
0.000 0.987 0.013
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.987 0.012
D58.2 Other haemoglobinopathies
0.000 0.987 0.012
D58.1 Hereditary elliptocytosis
0.000 0.987 0.012
E21.2 Other hyperparathyroidism
0.000 0.987 0.013
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.987 0.013
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.987 0.012
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.987 0.012
D51.2 Transcobalamin II deficiency
0.000 0.987 0.012
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.987 0.012
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.988 0.012
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.988 0.012
E61.9 Deficiency of nutrient element, unspecified
0.000 0.988 0.012
E61.8 Deficiency of other specified nutrient elements
0.000 0.988 0.012
E61.7 Deficiency of multiple nutrient elements
0.000 0.988 0.012
E61.6 Vanadium deficiency
0.000 0.988 0.012
E61.5 Molybdenum deficiency
0.000 0.988 0.012
E61.4 Chromium deficiency
0.000 0.988 0.012
E61.3 Manganese deficiency
0.000 0.988 0.012
E61.0 Copper deficiency
0.000 0.988 0.012
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.988 0.012
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.988 0.012
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.988 0.012
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.988 0.012
K59.8 Other specified functional intestinal disorders
0.012 0.988 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.988 0.012
E24.9 Cushing's syndrome, unspecified
0.000 0.988 0.011
S42.00 Fracture of clavicle (closed)
0.012 0.988 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.989 0.011
J31.2 Chronic pharyngitis
0.011 0.989 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.000 0.989 0.011
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.989 0.011
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.989 0.011
E67.8 Other specified hyperalimentation
0.000 0.989 0.011
E67.3 Hypervitaminosis D
0.000 0.989 0.011
E67.2 Megavitamin-B6 syndrome
0.000 0.989 0.011
E67.1 Hypercarotenaemia
0.000 0.989 0.011

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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