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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2523693
log Bayes Factor = 104.195
Chromosome 6   position 31,418,124  (GRCh37) Explore rs2523693 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
M45 Ankylosing spondylitis
0.000 0.005 0.995
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.010 0.990
E83.1 Disorders of iron metabolism
0.948 0.052 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.071 0.929
E07 Other disorders of thyroid
0.000 0.074 0.926
E07.9 Disorder of thyroid, unspecified
0.000 0.119 0.881
E03.8 Other specified hypothyroidism
0.000 0.122 0.878
E06 Thyroiditis
0.000 0.124 0.876
J45.9 Asthma, unspecified
0.000 0.156 0.844
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.230 0.769
E06.3 Autoimmune thyroiditis
0.000 0.247 0.753
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.252 0.748
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.254 0.746
C85.1 B-cell lymphoma, unspecified
0.000 0.257 0.743
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.275 0.725
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.279 0.721
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.282 0.718
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.284 0.716
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.286 0.714
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.286 0.714
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.286 0.714
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.286 0.714
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.286 0.714
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.286 0.714
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.287 0.713
C83.3 Large cell (diffuse)
0.000 0.287 0.713
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.295 0.705
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.296 0.704
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.301 0.699
E03.1 Congenital hypothyroidism without goitre
0.000 0.334 0.666
E07.1 Dyshormogenetic goitre
0.000 0.336 0.664
E07.0 Hypersecretion of calcitonin
0.000 0.336 0.664
E06.9 Thyroiditis, unspecified
0.000 0.337 0.663
E06.5 Other chronic thyroiditis
0.000 0.344 0.656
E06.1 Subacute thyroiditis
0.000 0.359 0.641
E06.4 Drug-induced thyroiditis
0.000 0.372 0.628
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.372 0.628
E06.0 Acute thyroiditis
0.000 0.372 0.628
E07.8 Other specified disorders of thyroid
0.000 0.377 0.623
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.398 0.602
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.406 0.594
C82.3 Follicular lymphoma grade IIIa
0.000 0.410 0.590
C82.2 Large cell, follicular
0.000 0.429 0.571
C82.0 Small cleaved cell, follicular
0.000 0.437 0.563
C82.4 Follicular lymphoma grade IIIb
0.000 0.440 0.560
C83.7 Burkitt's tumour
0.000 0.445 0.555
C81 Hodgkin's disease
0.000 0.451 0.549
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.451 0.549
C86 Other specified types of T/NK-cell lymphoma
0.000 0.453 0.547
C85.0 Lymphosarcoma
0.000 0.464 0.536
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.477 0.523
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.483 0.517
C82.6 Cutaneous follicle centre lymphoma
0.000 0.485 0.515
C82.5 Diffuse follicle centre lymphoma
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
C88 Malignant immunoproliferative diseases
0.000 0.486 0.514
C83.6 Undifferentiated (diffuse)
0.000 0.494 0.505
C83.5 Lymphoblastic (diffuse)
0.000 0.494 0.505
C83.4 Immunoblastic (diffuse)
0.000 0.494 0.505
C83.2 Mixed small and large cell (diffuse)
0.000 0.494 0.505
C81.9 Hodgkin's disease, unspecified
0.000 0.525 0.475
C94 Other leukaemias of specified cell type
0.000 0.527 0.472
C95 Leukaemia of unspecified cell type
0.000 0.537 0.463
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.543 0.457
C83.1 Small cleaved cell (diffuse)
0.000 0.552 0.448
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.560 0.440
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.563 0.437
C93 Monocytic leukaemia
0.000 0.563 0.437
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.578 0.422
C81.2 Mixed cellularity
0.000 0.581 0.419
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.581 0.418
C84.5 Other and unspecified T-cell lymphomas
0.000 0.588 0.412
C84.0 Mycosis fungoides
0.000 0.593 0.406
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.606 0.394
C81.3 Lymphocytic depletion
0.000 0.606 0.394
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.606 0.393
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.606 0.393
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.606 0.393
C84.3 Lymphoepithelioid lymphoma
0.000 0.606 0.393
C84.2 T-zone lymphoma
0.000 0.606 0.393
C84.1 Sezary's diease
0.000 0.606 0.393
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.608 0.392
C86.4 Blastic NK-cell lymphoma
0.000 0.608 0.392
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.608 0.392
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.608 0.392
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.608 0.392
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.608 0.392
C81.7 Other Hodgkin's disease
0.000 0.617 0.382
K90 Intestinal malabsorption
0.000 0.620 0.380
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.629 0.371
C96.8 Histiocytic sarcoma
0.000 0.629 0.371
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.629 0.371
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.629 0.371
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.629 0.371
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.629 0.371
C96.3 True histiocytic lymphoma
0.000 0.629 0.371
C96.2 Malignant mast cell tumour
0.000 0.629 0.371
C96.1 Malignant histiocytosis
0.000 0.629 0.371
C96.0 Letterer-Siwe disease
0.000 0.629 0.371
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.631 0.369
C88.7 Other malignant immunoproliferative diseases
0.000 0.631 0.369
C88.3 Immunoproliferative small intestinal disease
0.000 0.631 0.369
C88.2 Gamma heavy chain disease
0.000 0.631 0.369
C88.1 Alpha heavy chain disease
0.000 0.631 0.369
C95.9 Leukaemia, unspecified
0.000 0.641 0.358
C81.1 Nodular sclerosis
0.000 0.652 0.347
C91 Lymphoid leukaemia
0.000 0.656 0.343
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.657 0.343
C94.7 Other specified leukaemias
0.000 0.661 0.339
C94.5 Acute myelofibrosis
0.000 0.661 0.339
C94.4 Acute panmyelosis
0.000 0.661 0.339
C94.3 Mast cell leukaemia
0.000 0.661 0.339
C94.2 Acute megakaryoblastic leukaemia
0.000 0.661 0.339
C94.1 Chronic erythraemia
0.000 0.661 0.339
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.661 0.339
C95.7 Other leukaemia of unspecified cell type
0.000 0.668 0.332
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.668 0.332
C84.4 Peripheral T-cell lymphoma
0.000 0.670 0.330
C81.0 Lymphocytic predominance
0.000 0.672 0.328
C93.9 Monocytic leukaemia, unspecified
0.000 0.686 0.313
C93.7 Other monocytic leukaemia
0.000 0.686 0.313
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.686 0.313
C93.2 Subacute monocytic leukaemia
0.000 0.686 0.313
C93.0 Acute monocytic leukaemia
0.000 0.686 0.313
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.691 0.309
K90.9 Intestinal malabsorption, unspecified
0.000 0.700 0.300
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.702 0.296
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.705 0.294
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.711 0.288
C91.9 Lymphoid leukaemia, unspecified
0.000 0.712 0.288
C92 Myeloid leukaemia
0.000 0.725 0.275
K90.3 Pancreatic steatorrhoea
0.000 0.727 0.273
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.727 0.273
K90.1 Tropical sprue
0.000 0.727 0.273
C91.5 Adult T-cell leukaemia
0.000 0.728 0.272
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.729 0.271
C95.0 Acute leukaemia of unspecified cell type
0.000 0.733 0.267
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.753 0.246
C91.7 Other lymphoid leukaemia
0.000 0.753 0.246
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.753 0.246
C91.3 Prolymphocytic leukaemia
0.000 0.753 0.246
C91.2 Subacute lymphocytic leukaemia
0.000 0.753 0.246
C93.1 Chronic monocytic leukaemia
0.001 0.766 0.233
C92.1 Chronic myeloid leukaemia
0.000 0.768 0.232
E10 Insulin-dependent diabetes mellitus
0.000 0.775 0.225
E10-E14 Diabetes mellitus
0.000 0.779 0.221
E10.9 Without complications
0.000 0.781 0.219
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.782 0.218
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.001 0.789 0.210
E14 Unspecified diabetes mellitus
0.000 0.791 0.209
C91.0 Acute lymphoblastic leukaemia
0.000 0.793 0.207
K90.8 Other intestinal malabsorption
0.000 0.793 0.207
E10.3 With ophthalmic complications
0.000 0.794 0.206
E14.3 With ophthalmic complications
0.000 0.795 0.205
E10.2 With renal complications
0.000 0.798 0.202
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.802 0.197
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.802 0.197
C92.3 Myeloid sarcoma
0.000 0.802 0.197
C92.2 Subacute myeloid leukaemia
0.000 0.802 0.197
C92.5 Acute myelomonocytic leukaemia
0.000 0.812 0.188
E10.1 With ketoacidosis
0.000 0.819 0.181
J45 Asthma
0.000 0.822 0.178
C92.9 Myeloid leukaemia, unspecified
0.000 0.825 0.174
C92.7 Other myeloid leukaemia
0.000 0.828 0.172
E04 Other non-toxic goitre
0.000 0.829 0.171
E14.2 Withrenal complications
0.000 0.835 0.165
C90 Multiple myeloma and malignant plasma cell neoplasms
0.001 0.836 0.163
E10.7 With multiple complications
0.000 0.837 0.163
E10.6 With other specified complications
0.000 0.838 0.162
E10.8 With unspecified complications
0.000 0.838 0.162
E14.8 With unspecified complications
0.000 0.839 0.161
E14.5 With peripheral circulatory complications
0.000 0.841 0.159
E12 Malnutrition-related diabetes mellitus
0.000 0.841 0.159
C92.4 Acute promyelocytic leukaemia
0.000 0.842 0.158
E14.1 With ketoacidosis
0.000 0.844 0.156
E13 Other specified diabetes mellitus
0.000 0.849 0.151
E14.7 With multiple complications
0.000 0.850 0.150
E14.0 With coma
0.000 0.850 0.150
E10.4 With neurological complications
0.000 0.854 0.146
E14.6 With other specified complications
0.000 0.855 0.145
E14.4 With neurological complications
0.000 0.856 0.144
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.860 0.140
E10.0 With coma
0.000 0.861 0.139
C91.1 Chronic lymphocytic leukaemia
0.000 0.866 0.134
C91.4 Hairy-cell leukaemia
0.001 0.866 0.134
J45.1 Nonallergic asthma
0.000 0.866 0.133
E10.5 With peripheral circulatory complications
0.000 0.871 0.129
E40-E46 Malnutrition
0.000 0.871 0.129
J45.8 Mixed asthma
0.000 0.875 0.125
E04.8 Other specified non-toxic goitre
0.000 0.877 0.122
C90.1 Plasma cell leukaemia
0.001 0.883 0.116
E83 Disorders of mineral metabolism
0.116 0.883 0.001
E12.9 Without complications
0.000 0.886 0.114
E12.8 With unspecified complications
0.000 0.886 0.114
E12.7 With multiple complications
0.000 0.886 0.114
E12.6 With other specified complications
0.000 0.886 0.114
E12.5 With peripheral circulatory complications
0.000 0.886 0.114
E12.4 With neurological complications
0.000 0.886 0.114
E12.3 With ophthalmic complications
0.000 0.886 0.114
E12.2 With renal complications
0.000 0.886 0.114
E12.1 With ketoacidosis
0.000 0.886 0.114
E12.0 With coma
0.000 0.886 0.114
C83.0 Small cell (diffuse)
0.005 0.888 0.107
C90.3 Solitary plasmacytoma
0.001 0.889 0.110
E13.3 With ophthalmic complications
0.000 0.890 0.110
E13.8 With unspecified complications
0.000 0.891 0.109
E13.7 With multiple complications
0.000 0.891 0.109
E13.6 With other specified complications
0.000 0.891 0.109
E13.5 With peripheral circulatory complications
0.000 0.891 0.109
E13.4 With neurological complications
0.000 0.891 0.109
E13.2 With renal complications
0.000 0.891 0.109
E13.1 With ketoacidosis
0.000 0.891 0.109
E13.0 With coma
0.000 0.891 0.109
E15 Nondiabetic hypoglycaemic coma
0.000 0.899 0.100
E13.9 Without complications
0.000 0.901 0.099
E04.0 Non-toxic diffuse goitre
0.000 0.903 0.097
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.907 0.093
E45 Retarded development following protein-energy malnutrition
0.000 0.907 0.093
E43 Unspecified severe protein-energy malnutrition
0.000 0.907 0.093
E42 Marasmic kwashiorkor
0.000 0.907 0.093
E41 Nutritional marasmus
0.000 0.907 0.093
E40 Kwashiorkor
0.000 0.907 0.093
E04.9 Non-toxic goitre, unspecified
0.000 0.909 0.091
E04.2 Non-toxic multinodular goitre
0.000 0.911 0.089
E83.9 Disorder of mineral metabolism, unspecified
0.088 0.911 0.001
E50-E64 Other nutritional deficiencies
0.000 0.912 0.088
E83.8 Other disorders of mineral metabolism
0.083 0.916 0.001
E83.2 Disorders of zinc metabolism
0.083 0.916 0.001
E83.0 Disorders of copper metabolism
0.083 0.916 0.001
E16 Other disorders of pancreatic internal secretion
0.000 0.916 0.084
E83.3 Disorders of phosphorus metabolism
0.083 0.916 0.000
C92.0 Acute myeloid leukaemia
0.000 0.922 0.078
E58 Dietary calcium deficiency
0.000 0.927 0.073
E16.1 Other hypoglycaemia
0.000 0.930 0.070
E20-E35 Disorders of other endocrine glands
0.000 0.931 0.069
E44.1 Mild protein-energy malnutrition
0.000 0.933 0.067
E44.0 Moderate protein-energy malnutrition
0.000 0.933 0.067
E46 Unspecified protein-energy malnutrition
0.000 0.934 0.066
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.936 0.063
E63 Other nutritional deficiencies
0.000 0.936 0.063
E50 Vitamin A deficiency
0.000 0.936 0.063
E60 Dietary zinc deficiency
0.000 0.936 0.063
E59 Dietary selenium deficiency
0.000 0.936 0.063
E52 Niacin deficiency [pellagra]
0.000 0.936 0.063
E51 Thiamine deficiency
0.000 0.937 0.063
E29 Testicular dysfunction
0.000 0.939 0.061
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.940 0.060
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.940 0.060
E16.4 Abnormal secretion of gastrin
0.000 0.940 0.060
E16.3 Increased secretion of glucagon
0.000 0.940 0.060
E54 Ascorbic acid deficiency
0.000 0.940 0.060
E56 Other vitamin deficiencies
0.000 0.940 0.060
E24 Cushing's syndrome
0.000 0.940 0.060
E28 Ovarian dysfunction
0.000 0.940 0.060
C90.2 Plasmacytoma, extramedullary
0.001 0.941 0.057
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.943 0.056
G35 Multiple sclerosis
0.056 0.944 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.944 0.055
E29.1 Testicular hypofunction
0.000 0.945 0.055
E61 Deficiency of other nutrient elements
0.000 0.946 0.054
E55 Vitamin D deficiency
0.000 0.948 0.052
E25 Adrenogenital disorders
0.000 0.949 0.051
E28.3 Primary ovarian failure
0.000 0.949 0.051
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.950 0.050
E32 Diseases of thymus
0.000 0.950 0.050
E31 Polyglandular dysfunction
0.000 0.950 0.050
E30 Disorders of puberty, not elsewhere classified
0.000 0.950 0.050
E24.9 Cushing's syndrome, unspecified
0.000 0.951 0.049
E24.2 Drug-induced Cushing's syndrome
0.000 0.951 0.049
E14.9 Without complications
0.000 0.951 0.049
E24.0 Pituitary-dependent Cushing's disease
0.000 0.954 0.046
E23 Hypofunction and other disorders of pituitary gland
0.000 0.954 0.046
E28.2 Polycystic ovarian syndrome
0.000 0.954 0.046
E50.9 Vitamin A deficiency, unspecified
0.000 0.954 0.046
E50.8 Other manifestations of vitamin A deficiency
0.000 0.954 0.046
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.954 0.046
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.954 0.046
E50.5 Vitamin A deficiency with night blindness
0.000 0.954 0.046
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.954 0.046
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.954 0.046
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.954 0.046
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.954 0.046
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.954 0.046
E63.9 Nutritional deficiency, unspecified
0.000 0.954 0.046
E63.8 Other specified nutritional deficiencies
0.000 0.954 0.046
E63.1 Imbalance of constituents of food intake
0.000 0.954 0.046
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.954 0.046
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.954 0.046
E64.8 Sequelae of other nutritional deficiencies
0.000 0.954 0.046
E64.3 Sequelae of rickets
0.000 0.954 0.046
E64.2 Sequelae of vitamin C deficiency
0.000 0.954 0.046
E64.1 Sequelae of vitamin A deficiency
0.000 0.954 0.046
E64.0 Sequelae of protein-energy malnutrition
0.000 0.954 0.046
E51.9 Thiamine deficiency, unspecified
0.000 0.955 0.045
E51.8 Other manifestations of thiamine deficiency
0.000 0.955 0.045
E51.1 Beriberi
0.000 0.955 0.045
E51.2 Wernicke's encephalopathy
0.000 0.955 0.045
E29.9 Testicular dysfunction, unspecified
0.000 0.956 0.044
E29.8 Other testicular dysfunction
0.000 0.956 0.044
E29.0 Testicular hyperfunction
0.000 0.956 0.044
E56.9 Vitamin deficiency, unspecified
0.000 0.957 0.043
E56.8 Deficiency of other vitamins
0.000 0.957 0.043
E56.0 Deficiency of vitamin E
0.000 0.957 0.043
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.957 0.043
E24.3 Ectopic ACTH syndrome
0.000 0.957 0.043
E24.1 Nelson's syndrome
0.000 0.957 0.043
E28.9 Ovarian dysfunction, unspecified
0.000 0.957 0.043
E28.8 Other ovarian dysfunction
0.000 0.957 0.043
E28.1 Androgen excess
0.000 0.957 0.043
E28.0 Oestrogen excess
0.000 0.957 0.043
E83.5 Disorders of calcium metabolism
0.043 0.957 0.000
E22 Hyperfunction of pituitary gland
0.000 0.959 0.041
E61.2 Magnesium deficiency
0.000 0.959 0.041
E26 Hyperaldosteronism
0.000 0.960 0.040
E67 Other hyperalimentation
0.000 0.960 0.040
E68 Sequelae of hyperalimentation
0.000 0.960 0.040
E56.1 Deficiency of vitamin K
0.000 0.960 0.040
E23.2 Diabetes insipidus
0.000 0.961 0.039
E24.8 Other Cushing's syndrome
0.000 0.961 0.039
E61.9 Deficiency of nutrient element, unspecified
0.000 0.961 0.039
E61.8 Deficiency of other specified nutrient elements
0.000 0.961 0.039
E61.7 Deficiency of multiple nutrient elements
0.000 0.961 0.039
E61.6 Vanadium deficiency
0.000 0.961 0.039
E61.5 Molybdenum deficiency
0.000 0.961 0.039
E61.4 Chromium deficiency
0.000 0.961 0.039
E61.3 Manganese deficiency
0.000 0.961 0.039
E61.0 Copper deficiency
0.000 0.961 0.039
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.962 0.038
E55.0 Rickets, active
0.000 0.962 0.037
E25.9 Adrenogenital disorder, unspecified
0.000 0.963 0.037
E25.8 Other adrenogenital disorders
0.000 0.963 0.037
E30.9 Disorder of puberty, unspecified
0.000 0.964 0.036
E30.8 Other disorders of puberty
0.000 0.964 0.036
E30.1 Precocious puberty
0.000 0.964 0.036
E30.0 Delayed puberty
0.000 0.964 0.036
E31.9 Polyglandular dysfunction, unspecified
0.000 0.964 0.036
E31.8 Other polyglandular dysfunction
0.000 0.964 0.036
E31.1 Polyglandular hyperfunction
0.000 0.964 0.036
E31.0 Autoimmune polyglandular failure
0.000 0.964 0.036
E32.9 Disease of thymus, unspecified
0.000 0.964 0.036
E32.8 Other diseases of thymus
0.000 0.964 0.036
E32.1 Abscess of thymus
0.000 0.964 0.036
E32.0 Persistent hyperplasia of thymus
0.000 0.964 0.036
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.964 0.036
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.964 0.036
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.964 0.036
E20 Hypoparathyroidism
0.000 0.964 0.035
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.965 0.035
J45.0 Predominantly allergic asthma
0.000 0.966 0.034
E53 Deficiency of other B group vitamins
0.000 0.966 0.034
G35-G37 Demyelinating diseases of the central nervous system
0.033 0.967 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.967 0.033
E23.1 Drug-induced hypopituitarism
0.000 0.967 0.033
E23.6 Other disorders of pituitary gland
0.000 0.968 0.032
L40.9 Psoriasis, unspecified
0.032 0.968 0.000
M45-M49 Spondylopathies
0.000 0.968 0.032
E04.1 Non-toxic single thyroid nodule
0.000 0.970 0.030
E22.8 Other hyperfunction of pituitary gland
0.000 0.970 0.030
E26.9 Hyperaldosteronism, unspecified
0.000 0.970 0.029
G37 Other demyelinating diseases of central nervous system
0.030 0.970 0.000
E26.8 Other hyperaldosteronism
0.000 0.971 0.029
E26.1 Secondary hyperaldosteronism
0.000 0.971 0.029
E67.8 Other specified hyperalimentation
0.000 0.971 0.029
E67.3 Hypervitaminosis D
0.000 0.971 0.029
E67.2 Megavitamin-B6 syndrome
0.000 0.971 0.029
E67.1 Hypercarotenaemia
0.000 0.971 0.029
E67.0 Hypervitaminosis A
0.000 0.971 0.029
G37.9 Demyelinating disease of central nervous system, unspecified
0.028 0.972 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.972 0.028
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.972 0.028
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.973 0.027
E23.0 Hypopituitarism
0.000 0.973 0.027
E23.7 Disorder of pituitary gland, unspecified
0.000 0.973 0.027
E22.1 Hyperprolactinaemia
0.000 0.974 0.026
E55.9 Vitamin D deficiency, unspecified
0.000 0.974 0.026
E20.8 Other hypoparathyroidism
0.000 0.974 0.025
E20.0 Idiopathic hypoparathyroidism
0.000 0.974 0.025
E34 Other endocrine disorders
0.000 0.975 0.024
E61.1 Iron deficiency
0.000 0.975 0.025
E53.1 Pyridoxine deficiency
0.000 0.975 0.024
E53.0 Riboflavin deficiency
0.000 0.975 0.024
E78.5 Hyperlipidaemia, unspecified
0.000 0.975 0.025
E83.4 Disorders of magnesium metabolism
0.023 0.976 0.001
E27 Other disorders of adrenal gland
0.000 0.976 0.024
E20.1 Pseudohypoparathyroidism
0.000 0.976 0.023
G37.8 Other specified demyelinating diseases of central nervous system
0.022 0.977 0.000
G36 Other acute disseminated demyelination
0.022 0.978 0.000
K90-K93 Other diseases of the digestive system
0.000 0.978 0.022
E27.1 Primary adrenocortical insufficiency
0.000 0.978 0.022
G37.5 Concentric sclerosis [Balo]
0.021 0.978 0.000
G37.4 Subacute necrotising myelitis
0.021 0.978 0.000
G37.2 Central pontine myelinolysis
0.021 0.978 0.000
G37.1 Central demyelination of corpus callosum
0.021 0.978 0.000
G37.0 Diffuse sclerosis
0.021 0.978 0.000
M49 Spondylopathies in diseases classified elsewhere
0.000 0.978 0.021
E53.9 Vitamin B deficiency, unspecified
0.000 0.979 0.021
E21.4 Other specified disorders of parathyroid gland
0.000 0.979 0.021
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.979 0.021
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.980 0.020
E65 Localised adiposity
0.001 0.980 0.019
E21.2 Other hyperparathyroidism
0.000 0.981 0.019
E26.0 Primary hyperaldosteronism
0.000 0.981 0.018
E34.5 Androgen resistance syndrome
0.000 0.982 0.018
E34.4 Constitutional tall stature
0.000 0.982 0.018
E34.3 Short stature, not elsewhere classified
0.000 0.982 0.018
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.982 0.018
E34.1 Other hypersecretion of intestinal hormones
0.000 0.982 0.018
E22.0 Acromegaly and pituitary gigantism
0.000 0.983 0.017
E27.5 Adrenomedullary hyperfunction
0.000 0.983 0.017
E27.0 Other adrenocortical overactivity
0.000 0.983 0.017
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.983 0.017
F20.9 Schizophrenia, unspecified
0.017 0.983 0.000
G36.9 Acute disseminated demyelination, unspecified
0.016 0.984 0.000
G36.8 Other specified acute disseminated demyelination
0.016 0.984 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.016 0.984 0.000
E34.8 Other specified endocrine disorders
0.000 0.984 0.016
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.984 0.016
M49.8 Spondylopathy in other diseases classified elsewhere
0.000 0.984 0.015
M49.4 Neuropathic spondylopathy
0.000 0.984 0.015
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.000 0.984 0.015
M49.2 Enterobacterial spondylitis
0.000 0.984 0.015
M49.1 Brucella spondylitis
0.000 0.984 0.015
M49.0 Tuberculosis of spine
0.000 0.984 0.015
E20.9 Hypoparathyroidism, unspecified
0.001 0.984 0.015
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.015 0.985 0.000
C90.0 Multiple myeloma
0.001 0.985 0.014
M49.5 Collapsed vertebra in diseases classified elsewhere
0.000 0.986 0.014
E27.9 Disorder of adrenal gland, unspecified
0.000 0.986 0.014
G36.0 Neuromyelitis optica [Devic]
0.014 0.986 0.000
M46 Other inflammatory spondylopathies
0.000 0.986 0.014
E34.0 Carcinoid syndrome
0.001 0.988 0.012
E21.3 Hyperparathyroidism, unspecified
0.000 0.988 0.012
N83.1 Corpus luteum cyst
0.000 0.988 0.012
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.988 0.011
K93.1 Megacolon in Chagas' disease
0.000 0.988 0.011
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.988 0.011
M49.09 Tuberculosis of spine (Site unspecified)
0.000 0.988 0.011
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.000 0.988 0.011
M49.07 Tuberculosis of spine (Lumbosacral region)
0.000 0.988 0.011
M49.06 Tuberculosis of spine (Lumbar region)
0.000 0.988 0.011
M49.05 Tuberculosis of spine (Thoracolumbar region)
0.000 0.988 0.011
M49.04 Tuberculosis of spine (Thoracic region)
0.000 0.988 0.011
M49.03 Tuberculosis of spine (Cervicothoracic region)
0.000 0.988 0.011
M49.02 Tuberculosis of spine (Cervical region)
0.000 0.988 0.011
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)
0.000 0.988 0.011
M49.00 Tuberculosis of spine (Multiple sites in spine)
0.000 0.988 0.011
M49.19 Brucella spondylitis (Site unspecified)
0.000 0.988 0.011
M49.18 Brucella spondylitis (Sacral and sacrococcygeal region)
0.000 0.988 0.011
M49.17 Brucella spondylitis (Lumbosacral region)
0.000 0.988 0.011
M49.16 Brucella spondylitis (Lumbar region)
0.000 0.988 0.011
M49.15 Brucella spondylitis (Thoracolumbar region)
0.000 0.988 0.011
M49.14 Brucella spondylitis (Thoracic region)
0.000 0.988 0.011
M49.13 Brucella spondylitis (Cervicothoracic region)
0.000 0.988 0.011
M49.12 Brucella spondylitis (Cervical region)
0.000 0.988 0.011
M49.11 Brucella spondylitis (Occipito-atlanto-axial region)
0.000 0.988 0.011
M49.10 Brucella spondylitis (Multiple sites in spine)
0.000 0.988 0.011
M49.29 Enterobacterial spondylitis (Site unspecified)
0.000 0.988 0.011
M49.28 Enterobacterial spondylitis (Sacral and sacrococcygeal region)
0.000 0.988 0.011
M49.27 Enterobacterial spondylitis (Lumbosacral region)
0.000 0.988 0.011
M49.26 Enterobacterial spondylitis (Lumbar region)
0.000 0.988 0.011
M49.25 Enterobacterial spondylitis (Thoracolumbar region)
0.000 0.988 0.011
M49.24 Enterobacterial spondylitis (Thoracic region)
0.000 0.988 0.011
M49.23 Enterobacterial spondylitis (Cervicothoracic region)
0.000 0.988 0.011
M49.22 Enterobacterial spondylitis (Cervical region)
0.000 0.988 0.011
M49.21 Enterobacterial spondylitis (Occipito-atlanto-axial region)
0.000 0.988 0.011
M49.20 Enterobacterial spondylitis (Multiple sites in spine)
0.000 0.988 0.011
M49.39 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Site unspecified)
0.000 0.988 0.011
M49.38 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Sacral and sacrococcygeal region)
0.000 0.988 0.011
M49.37 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbosacral region)
0.000 0.988 0.011
M49.36 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbar region)
0.000 0.988 0.011
M49.35 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracolumbar region)
0.000 0.988 0.011
M49.34 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracic region)
0.000 0.988 0.011
M49.33 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervicothoracic region)
0.000 0.988 0.011
M49.32 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervical region)
0.000 0.988 0.011
M49.31 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Occipito-atlanto-axial region)
0.000 0.988 0.011
M49.30 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Multiple sites in spine)
0.000 0.988 0.011
M49.49 Neuropathic spondylopathy (Site unspecified)
0.000 0.988 0.011

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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