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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2523790
log Bayes Factor = 27.6779
Chromosome 6   position 29,803,650  (GRCh37) Explore rs2523790 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E70-E90 Metabolic disorders
0.000 0.003 0.997
E83 Disorders of mineral metabolism
0.000 0.004 0.996
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.005 0.995
E16 Other disorders of pancreatic internal secretion
0.000 0.008 0.992
E16.2 Hypoglycaemia, unspecified
0.000 0.009 0.991
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.021 0.979
E00-E07 Disorders of thyroid gland
0.000 0.022 0.978
E05.9 Thyrotoxicosis, unspecified
0.000 0.027 0.973
E10.9 Without complications
0.000 0.034 0.966
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.037 0.963
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.050 0.950
E10.1 With ketoacidosis
0.000 0.051 0.949
E10.3 With ophthalmic complications
0.000 0.058 0.942
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.063 0.937
E89.0 Postprocedural hypothyroidism
0.000 0.102 0.898
E80.4 Gilbert's syndrome
0.000 0.102 0.898
E10.4 With neurological complications
0.000 0.116 0.884
L40.8 Other psoriasis
0.000 0.176 0.824
E10.6 With other specified complications
0.000 0.185 0.815
E10.5 With peripheral circulatory complications
0.000 0.195 0.805
E10.0 With coma
0.000 0.198 0.802
E85 Amyloidosis
0.000 0.199 0.801
E89.2 Postprocedural hypoparathyroidism
0.000 0.225 0.774
E73 Lactose intolerance
0.000 0.227 0.773
E10.2 With renal complications
0.000 0.241 0.759
E14 Unspecified diabetes mellitus
0.000 0.256 0.744
L40.3 Pustulosis palmaris et plantaris
0.000 0.258 0.742
E11 Non-insulin-dependent diabetes mellitus
0.000 0.260 0.740
E80.2 Other porphyria
0.000 0.269 0.731
E79 Disorders of purine and pyrimidine metabolism
0.000 0.276 0.724
E80.6 Other disorders of bilirubin metabolism
0.000 0.282 0.718
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.284 0.716
E11.3 With ophthalmic complications
0.000 0.284 0.716
E84 Cystic fibrosis
0.000 0.285 0.715
E77 Disorders of glycoprotein metabolism
0.000 0.285 0.715
E76 Disorders of glycosaminoglycan metabolism
0.000 0.285 0.715
E72 Other disorders of amino-acid metabolism
0.000 0.285 0.715
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.285 0.715
E70 Disorders of aromatic amino-acid metabolism
0.000 0.285 0.715
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.285 0.715
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.286 0.714
E83.8 Other disorders of mineral metabolism
0.000 0.286 0.714
E83.2 Disorders of zinc metabolism
0.000 0.286 0.714
E83.0 Disorders of copper metabolism
0.000 0.286 0.714
E15 Nondiabetic hypoglycaemic coma
0.000 0.286 0.713
E74 Other disorders of carbohydrate metabolism
0.000 0.287 0.713
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.287 0.713
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.288 0.711
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.288 0.711
E16.4 Abnormal secretion of gastrin
0.000 0.288 0.711
E16.3 Increased secretion of glucagon
0.000 0.288 0.711
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.293 0.707
E16.1 Other hypoglycaemia
0.000 0.295 0.705
E80.1 Porphyria cutanea tarda
0.000 0.296 0.704
E05.5 Thyroid crisis or storm
0.000 0.298 0.702
E05.4 Thyrotoxicosis factitia
0.000 0.298 0.702
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.298 0.702
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.298 0.702
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.299 0.701
E00 Congenital iodine-deficiency syndrome
0.000 0.299 0.701
E89.4 Postprocedural ovarian failure
0.000 0.301 0.699
N40 Hyperplasia of prostate
0.699 0.301 0.000
E14.3 With ophthalmic complications
0.000 0.310 0.690
E05.8 Other thyrotoxicosis
0.000 0.316 0.684
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.319 0.681
E80.5 Crigler-Najjar syndrome
0.000 0.319 0.681
E80.3 Defects of catalase and peroxydase
0.000 0.319 0.681
E80.0 Hereditary erythropoietic porphyria
0.000 0.319 0.681
E13 Other specified diabetes mellitus
0.000 0.320 0.680
E10.8 With unspecified complications
0.000 0.320 0.680
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.328 0.672
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.328 0.672
E89.5 Postprocedural testicular hypofunction
0.000 0.328 0.672
E85.9 Amyloidosis, unspecified
0.000 0.336 0.664
L40.4 Guttate psoriasis
0.000 0.346 0.653
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.354 0.646
E85.4 Organ-limited amyloidosis
0.000 0.363 0.636
L40.0 Psoriasis vulgaris
0.000 0.370 0.630
E89.3 Postprocedural hypopituitarism
0.000 0.380 0.620
E40-E46 Malnutrition
0.000 0.386 0.614
E73.9 Lactose intolerance, unspecified
0.000 0.387 0.613
E88 Other metabolic disorders
0.000 0.388 0.612
E11.5 With peripheral circulatory complications
0.000 0.391 0.609
E50-E64 Other nutritional deficiencies
0.000 0.392 0.607
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.397 0.603
E89.1 Postprocedural hypoinsulinaemia
0.000 0.414 0.586
E07 Other disorders of thyroid
0.000 0.421 0.579
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.426 0.574
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.426 0.574
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.426 0.574
E14.6 With other specified complications
0.000 0.439 0.561
E85.3 Secondary systemic amyloidosis
0.000 0.439 0.561
E11.1 With ketoacidosis
0.000 0.441 0.559
E73.8 Other lactose intolerance
0.000 0.446 0.554
E73.1 Secondary lactase deficiency
0.000 0.446 0.554
E73.0 Congenital lactase deficiency
0.000 0.446 0.554
E14.8 With unspecified complications
0.000 0.447 0.553
E14.5 With peripheral circulatory complications
0.000 0.447 0.553
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.452 0.548
E11.8 With unspecified complications
0.000 0.453 0.547
E14.4 With neurological complications
0.000 0.461 0.539
E14.7 With multiple complications
0.000 0.466 0.533
E14.0 With coma
0.000 0.466 0.533
E11.7 With multiple complications
0.000 0.469 0.531
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.472 0.528
E14.1 With ketoacidosis
0.000 0.480 0.520
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.481 0.519
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.481 0.519
E79.1 Lesch-Nyhan syndrome
0.000 0.481 0.519
E11.4 With neurological complications
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.513
E12.8 With unspecified complications
0.000 0.486 0.513
E12.7 With multiple complications
0.000 0.486 0.513
E12.6 With other specified complications
0.000 0.486 0.513
E12.5 With peripheral circulatory complications
0.000 0.486 0.513
E12.4 With neurological complications
0.000 0.486 0.513
E12.3 With ophthalmic complications
0.000 0.486 0.513
E12.2 With renal complications
0.000 0.486 0.513
E12.1 With ketoacidosis
0.000 0.486 0.513
E12.0 With coma
0.000 0.486 0.513
E03 Other hypothyroidism
0.000 0.487 0.513
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.487 0.512
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.487 0.512
E70.3 Albinism
0.000 0.487 0.512
E70.2 Disorders of tyrosine metabolism
0.000 0.487 0.512
E70.1 Other hyperphenylalaninaemias
0.000 0.487 0.512
E70.0 Classical phenylketonuria
0.000 0.487 0.512
E71.3 Disorders of fatty-acid metabolism
0.000 0.487 0.512
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.487 0.512
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.487 0.512
E71.0 Maple-syrup-urine disease
0.000 0.487 0.512
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.487 0.512
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.487 0.512
E72.5 Disorders of glycine metabolism
0.000 0.487 0.512
E72.4 Disorders of ornithine metabolism
0.000 0.487 0.512
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.487 0.512
E72.2 Disorders of urea cycle metabolism
0.000 0.487 0.512
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.487 0.512
E72.0 Disorders of amino-acid transport
0.000 0.487 0.512
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.487 0.512
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.487 0.512
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.487 0.512
E76.2 Other mucopolysaccharidoses
0.000 0.487 0.512
E76.1 Mucopolysaccharidosis, type II
0.000 0.487 0.512
E76.0 Mucopolysaccharidosis, type I
0.000 0.487 0.512
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.487 0.512
E77.8 Other disorders of glycoprotein metabolism
0.000 0.487 0.512
E77.1 Defects in glycoprotein degradation
0.000 0.487 0.512
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.487 0.512
E84.9 Cystic fibrosis, unspecified
0.000 0.487 0.512
E84.8 Cystic fibrosis with other manifestations
0.000 0.487 0.512
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.487 0.512
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.487 0.512
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.489 0.511
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.489 0.511
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.489 0.511
E74.2 Disorders of galactose metabolism
0.000 0.489 0.511
E74.1 Disorders of fructose metabolism
0.000 0.489 0.511
E74.0 Glycogen storage disease
0.000 0.489 0.511
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.490 0.509
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.497 0.503
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.497 0.503
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.497 0.503
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.497 0.503
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.497 0.503
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.497 0.503
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.497 0.503
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.497 0.503
E85.8 Other amyloidosis
0.000 0.500 0.500
E13.8 With unspecified complications
0.000 0.512 0.487
E13.7 With multiple complications
0.000 0.512 0.487
E13.6 With other specified complications
0.000 0.512 0.487
E13.5 With peripheral circulatory complications
0.000 0.512 0.487
E13.4 With neurological complications
0.000 0.512 0.487
E13.3 With ophthalmic complications
0.000 0.512 0.487
E13.2 With renal complications
0.000 0.512 0.487
E13.1 With ketoacidosis
0.000 0.512 0.487
E13.0 With coma
0.000 0.512 0.487
E65-E68 Obesity and other hyperalimentation
0.000 0.519 0.481
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.523 0.477
E75.6 Lipid storage disorder, unspecified
0.000 0.537 0.463
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.537 0.463
E75.3 Sphingolipidosis, unspecified
0.000 0.537 0.463
E75.2 Other sphingolipidosis
0.000 0.537 0.463
E75.1 Other gangliosidosis
0.000 0.537 0.463
E75.0 GM2 gangliosidosis
0.000 0.537 0.463
E14.2 Withrenal complications
0.000 0.537 0.462
E83.3 Disorders of phosphorus metabolism
0.000 0.539 0.460
E58 Dietary calcium deficiency
0.000 0.540 0.460
E53 Deficiency of other B group vitamins
0.000 0.544 0.456
E13.9 Without complications
0.000 0.549 0.451
E11.0 With coma
0.000 0.549 0.451
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.555 0.444
K90 Intestinal malabsorption
0.000 0.560 0.440
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.560 0.440
E45 Retarded development following protein-energy malnutrition
0.000 0.560 0.440
E43 Unspecified severe protein-energy malnutrition
0.000 0.560 0.440
E42 Marasmic kwashiorkor
0.000 0.560 0.440
E41 Nutritional marasmus
0.000 0.560 0.440
E40 Kwashiorkor
0.000 0.560 0.440
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.564 0.436
E63 Other nutritional deficiencies
0.000 0.564 0.436
E56 Other vitamin deficiencies
0.000 0.564 0.436
E50 Vitamin A deficiency
0.000 0.564 0.436
E60 Dietary zinc deficiency
0.000 0.564 0.436
E59 Dietary selenium deficiency
0.000 0.564 0.436
E54 Ascorbic acid deficiency
0.000 0.564 0.436
E52 Niacin deficiency [pellagra]
0.000 0.564 0.436
E51 Thiamine deficiency
0.000 0.566 0.434
E07.1 Dyshormogenetic goitre
0.000 0.585 0.415
E07.0 Hypersecretion of calcitonin
0.000 0.585 0.415
E88.8 Other specified metabolic disorders
0.000 0.590 0.410
E11.6 With other specified complications
0.000 0.596 0.404
E88.3 Tumour lysis syndrome
0.000 0.597 0.403
E88.9 Metabolic disorder, unspecified
0.000 0.598 0.402
E88.2 Lipomatosis, not elsewhere classified
0.000 0.601 0.399
E75.5 Other lipid storage disorders
0.000 0.606 0.394
E61 Deficiency of other nutrient elements
0.000 0.615 0.385
E03.8 Other specified hypothyroidism
0.000 0.618 0.382
E07.9 Disorder of thyroid, unspecified
0.000 0.621 0.379
E03.5 Myxoedema coma
0.000 0.632 0.368
E03.4 Atrophy of thyroid (acquired)
0.000 0.632 0.368
E03.3 Postinfectious hypothyroidism
0.000 0.632 0.368
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.632 0.368
E11.2 With renal complications
0.000 0.633 0.367
E53.8 Deficiency of other specified B group vitamins
0.000 0.638 0.362
E03.1 Congenital hypothyroidism without goitre
0.000 0.640 0.360
K90.9 Intestinal malabsorption, unspecified
0.000 0.642 0.358
E65 Localised adiposity
0.000 0.648 0.352
E67 Other hyperalimentation
0.000 0.655 0.345
E68 Sequelae of hyperalimentation
0.000 0.655 0.345
E07.8 Other specified disorders of thyroid
0.000 0.656 0.344
E46 Unspecified protein-energy malnutrition
0.000 0.662 0.338
E53.1 Pyridoxine deficiency
0.000 0.673 0.327
E53.0 Riboflavin deficiency
0.000 0.673 0.327
E55 Vitamin D deficiency
0.000 0.676 0.324
K90.3 Pancreatic steatorrhoea
0.000 0.684 0.316
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.684 0.316
K90.1 Tropical sprue
0.000 0.684 0.316
E44.1 Mild protein-energy malnutrition
0.000 0.684 0.316
E44.0 Moderate protein-energy malnutrition
0.000 0.684 0.316
E50.9 Vitamin A deficiency, unspecified
0.000 0.687 0.312
E50.8 Other manifestations of vitamin A deficiency
0.000 0.687 0.312
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.687 0.312
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.687 0.312
E50.5 Vitamin A deficiency with night blindness
0.000 0.687 0.312
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.687 0.312
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.687 0.312
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.687 0.312
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.687 0.312
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.687 0.312
E56.9 Vitamin deficiency, unspecified
0.000 0.687 0.312
E56.8 Deficiency of other vitamins
0.000 0.687 0.312
E56.1 Deficiency of vitamin K
0.000 0.687 0.312
E56.0 Deficiency of vitamin E
0.000 0.687 0.312
E63.9 Nutritional deficiency, unspecified
0.000 0.687 0.312
E63.8 Other specified nutritional deficiencies
0.000 0.687 0.312
E63.1 Imbalance of constituents of food intake
0.000 0.687 0.312
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.687 0.312
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.687 0.312
E64.8 Sequelae of other nutritional deficiencies
0.000 0.687 0.312
E64.3 Sequelae of rickets
0.000 0.687 0.312
E64.2 Sequelae of vitamin C deficiency
0.000 0.687 0.312
E64.1 Sequelae of vitamin A deficiency
0.000 0.687 0.312
E64.0 Sequelae of protein-energy malnutrition
0.000 0.687 0.312
E51.9 Thiamine deficiency, unspecified
0.000 0.688 0.311
E51.8 Other manifestations of thiamine deficiency
0.000 0.688 0.311
E51.1 Beriberi
0.000 0.688 0.311
E51.2 Wernicke's encephalopathy
0.000 0.690 0.310
E03.9 Hypothyroidism, unspecified
0.000 0.690 0.310
K90.8 Other intestinal malabsorption
0.000 0.692 0.307
E53.9 Vitamin B deficiency, unspecified
0.000 0.695 0.305
E61.9 Deficiency of nutrient element, unspecified
0.000 0.724 0.276
E61.8 Deficiency of other specified nutrient elements
0.000 0.724 0.276
E61.7 Deficiency of multiple nutrient elements
0.000 0.724 0.276
E61.6 Vanadium deficiency
0.000 0.724 0.276
E61.5 Molybdenum deficiency
0.000 0.724 0.276
E61.4 Chromium deficiency
0.000 0.724 0.276
E61.3 Manganese deficiency
0.000 0.724 0.276
E61.2 Magnesium deficiency
0.000 0.724 0.276
E61.0 Copper deficiency
0.000 0.724 0.276
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.731 0.269
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.735 0.264
E83.4 Disorders of magnesium metabolism
0.000 0.750 0.250
E67.8 Other specified hyperalimentation
0.000 0.752 0.247
E67.3 Hypervitaminosis D
0.000 0.752 0.247
E67.2 Megavitamin-B6 syndrome
0.000 0.752 0.247
E67.1 Hypercarotenaemia
0.000 0.752 0.247
E67.0 Hypervitaminosis A
0.000 0.752 0.247
E55.0 Rickets, active
0.000 0.767 0.233
E04 Other non-toxic goitre
0.000 0.768 0.232
E06 Thyroiditis
0.002 0.770 0.229
L40-L45 Papulosquamous disorders
0.000 0.771 0.229
E61.1 Iron deficiency
0.000 0.775 0.225
E04.8 Other specified non-toxic goitre
0.000 0.833 0.167
E06.4 Drug-induced thyroiditis
0.001 0.835 0.164
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.001 0.835 0.164
E06.0 Acute thyroiditis
0.001 0.835 0.164
L44 Other papulosquamous disorders
0.000 0.836 0.164
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.836 0.164
L42 Pityriasis rosea
0.000 0.837 0.163
E04.0 Non-toxic diffuse goitre
0.000 0.845 0.155
E04.1 Non-toxic single thyroid nodule
0.000 0.848 0.152
L41 Parapsoriasis
0.000 0.856 0.144
E06.1 Subacute thyroiditis
0.001 0.856 0.143
E06.5 Other chronic thyroiditis
0.001 0.860 0.139
E83.5 Disorders of calcium metabolism
0.000 0.874 0.126
E55.9 Vitamin D deficiency, unspecified
0.000 0.879 0.121
L44.9 Papulosquamous disorder, unspecified
0.000 0.882 0.118
L44.8 Other specified papulosquamous disorders
0.000 0.882 0.118
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.882 0.118
L44.3 Lichen ruber moniliformis
0.000 0.882 0.118
L44.2 Lichen striatus
0.000 0.882 0.118
L44.1 Lichen nitidus
0.000 0.882 0.118
L44.0 Pityriasis rubra pilaris
0.000 0.882 0.118
E06.9 Thyroiditis, unspecified
0.002 0.891 0.107
L43 Lichen planus
0.000 0.895 0.105
L41.9 Parapsoriasis, unspecified
0.000 0.896 0.103
L41.8 Other parapsoriasis
0.000 0.896 0.103
L41.5 Retiform parapsoriasis
0.000 0.896 0.103
L41.4 Large plaque parapsoriasis
0.000 0.896 0.103
L41.3 Small plaque parapsoriasis
0.000 0.896 0.103
L41.2 Lymphomatoid papulosis
0.000 0.896 0.103
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.896 0.103
E66 Obesity
0.000 0.911 0.089
E04.9 Non-toxic goitre, unspecified
0.000 0.913 0.087
L41.1 Pityriasis lichenoides chronica
0.001 0.916 0.084
L43.3 Subacute (active) lichen planus
0.000 0.924 0.076
L43.2 Lichenoid drug reaction
0.000 0.924 0.076
L43.1 Bullous lichen planus
0.000 0.924 0.076
L43.0 Hypertrophic lichen planus
0.000 0.924 0.076
E06.3 Autoimmune thyroiditis
0.001 0.925 0.074
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.926 0.074
E20-E35 Disorders of other endocrine glands
0.000 0.931 0.069
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.931 0.069
E66.1 Drug-induced obesity
0.000 0.936 0.064
E04.2 Non-toxic multinodular goitre
0.000 0.936 0.064
E78.8 Other disorders of lipoprotein metabolism
0.000 0.937 0.063
L43.8 Other lichen planus
0.000 0.940 0.059
E78.6 Lipoprotein deficiency
0.000 0.942 0.058
E34 Other endocrine disorders
0.000 0.944 0.056
E66.0 Obesity due to excess calories
0.000 0.946 0.054
E24 Cushing's syndrome
0.000 0.947 0.053
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.950 0.050
E32 Diseases of thymus
0.000 0.950 0.050
E31 Polyglandular dysfunction
0.000 0.950 0.050
E30 Disorders of puberty, not elsewhere classified
0.000 0.950 0.050
E78.4 Other hyperlipidaemia
0.000 0.950 0.049
E25 Adrenogenital disorders
0.000 0.951 0.049
E34.9 Endocrine disorder, unspecified
0.000 0.951 0.049
E20 Hypoparathyroidism
0.000 0.951 0.048
L43.9 Lichen planus, unspecified
0.000 0.952 0.048
E78.3 Hyperchylomicronaemia
0.000 0.952 0.048
E28 Ovarian dysfunction
0.000 0.953 0.047
E78.1 Pure hyperglyceridaemia
0.000 0.955 0.045
E29 Testicular dysfunction
0.000 0.959 0.041
E34.5 Androgen resistance syndrome
0.000 0.959 0.040
E34.4 Constitutional tall stature
0.000 0.959 0.040
E34.3 Short stature, not elsewhere classified
0.000 0.959 0.040
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.959 0.040
E34.1 Other hypersecretion of intestinal hormones
0.000 0.959 0.040
E24.2 Drug-induced Cushing's syndrome
0.000 0.960 0.040
E78.2 Mixed hyperlipidaemia
0.000 0.960 0.040
E28.3 Primary ovarian failure
0.000 0.960 0.040
E24.9 Cushing's syndrome, unspecified
0.000 0.961 0.039
E24.0 Pituitary-dependent Cushing's disease
0.000 0.961 0.039
E26 Hyperaldosteronism
0.000 0.961 0.038
E34.8 Other specified endocrine disorders
0.000 0.961 0.038
E34.0 Carcinoid syndrome
0.000 0.962 0.038
E24.8 Other Cushing's syndrome
0.000 0.962 0.038
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.962 0.038
E24.3 Ectopic ACTH syndrome
0.000 0.962 0.038
E24.1 Nelson's syndrome
0.000 0.962 0.038
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.963 0.036
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.964 0.036
E27 Other disorders of adrenal gland
0.000 0.964 0.036
E30.9 Disorder of puberty, unspecified
0.000 0.964 0.036
E30.8 Other disorders of puberty
0.000 0.964 0.036
E30.1 Precocious puberty
0.000 0.964 0.036
E30.0 Delayed puberty
0.000 0.964 0.036
E31.9 Polyglandular dysfunction, unspecified
0.000 0.964 0.036
E31.8 Other polyglandular dysfunction
0.000 0.964 0.036
E31.1 Polyglandular hyperfunction
0.000 0.964 0.036
E31.0 Autoimmune polyglandular failure
0.000 0.964 0.036
E32.9 Disease of thymus, unspecified
0.000 0.964 0.036
E32.8 Other diseases of thymus
0.000 0.964 0.036
E32.1 Abscess of thymus
0.000 0.964 0.036
E32.0 Persistent hyperplasia of thymus
0.000 0.964 0.036
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.964 0.036
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.964 0.036
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.964 0.036
E25.9 Adrenogenital disorder, unspecified
0.000 0.964 0.035
E25.8 Other adrenogenital disorders
0.000 0.964 0.035
E20.8 Other hypoparathyroidism
0.000 0.965 0.035
E20.1 Pseudohypoparathyroidism
0.000 0.965 0.035
E20.0 Idiopathic hypoparathyroidism
0.000 0.965 0.035
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.965 0.034
E22 Hyperfunction of pituitary gland
0.000 0.966 0.034
E20.9 Hypoparathyroidism, unspecified
0.000 0.966 0.034
E28.9 Ovarian dysfunction, unspecified
0.000 0.966 0.033
E28.8 Other ovarian dysfunction
0.000 0.966 0.033
E28.1 Androgen excess
0.000 0.966 0.033
E28.0 Oestrogen excess
0.000 0.966 0.033
E14.9 Without complications
0.000 0.966 0.034
E87.3 Alkalosis
0.000 0.966 0.033
N40-N51 Diseases of male genital organs
0.033 0.967 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.968 0.032
I71 Aortic aneurysm and dissection
0.032 0.968 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.969 0.031
I71.0 Dissection of aorta [any part]
0.031 0.969 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.031 0.969 0.000
L03.1 Cellulitis of other parts of limb
0.000 0.970 0.030
N42.1 Congestion and haemorrhage of prostate
0.030 0.970 0.000
N41 Inflammatory diseases of prostate
0.030 0.970 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.030 0.970 0.000
N42 Other disorders of prostate
0.030 0.970 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.030 0.970 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.970 0.029
E29.8 Other testicular dysfunction
0.000 0.970 0.029
E29.0 Testicular hyperfunction
0.000 0.970 0.029
K90-K93 Other diseases of the digestive system
0.000 0.972 0.028
E26.8 Other hyperaldosteronism
0.000 0.972 0.028
E26.1 Secondary hyperaldosteronism
0.000 0.972 0.028
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.972 0.028
E27.8 Other specified disorders of adrenal gland
0.000 0.973 0.027
E27.2 Addisonian crisis
0.000 0.973 0.027
M06.9 Rheumatoid arthritis, unspecified
0.000 0.973 0.027
I71.3 Abdominal aortic aneurysm, ruptured
0.027 0.973 0.000
E87.4 Mixed disorder of acid-base balance
0.000 0.974 0.026
E27.5 Adrenomedullary hyperfunction
0.000 0.974 0.026
E27.0 Other adrenocortical overactivity
0.000 0.974 0.026
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.025 0.975 0.000
N46 Male infertility
0.025 0.975 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.975 0.024
E22.8 Other hyperfunction of pituitary gland
0.000 0.975 0.024
N44 Torsion of testis
0.025 0.975 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.024 0.975 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.975 0.024
N42.0 Calculus of prostate
0.025 0.975 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.024 0.976 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.976 0.024
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.977 0.023
I71.8 Aortic aneurysm of unspecified site, ruptured
0.023 0.977 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.023 0.977 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.978 0.022
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.022 0.978 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.978 0.022
E26.0 Primary hyperaldosteronism
0.000 0.978 0.022
N41.8 Other inflammatory diseases of prostate
0.022 0.978 0.000
N41.3 Prostatocystitis
0.022 0.978 0.000
N41.2 Abscess of prostate
0.022 0.978 0.000
N42.3 Dysplasia of prostate
0.022 0.978 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.978 0.022
M06 Other rheumatoid arthritis
0.000 0.978 0.022
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.021 0.979 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.979 0.020
N42.8 Other specified disorders of prostate
0.021 0.979 0.000
E29.1 Testicular hypofunction
0.000 0.979 0.020
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.979 0.020
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.980 0.020
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.980 0.020
E23 Hypofunction and other disorders of pituitary gland
0.000 0.980 0.020
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.980 0.020
N45 Orchitis and epididymitis
0.020 0.980 0.000
E66.8 Other obesity
0.000 0.981 0.019
E87.0 Hyperosmolality and hypernatraemia
0.000 0.981 0.019
N41.0 Acute prostatitis
0.019 0.981 0.000
N42.2 Atrophy of prostate
0.019 0.981 0.000
E22.1 Hyperprolactinaemia
0.000 0.982 0.018
N51.2 Balanitis in diseases classified elsewhere
0.018 0.982 0.000
M06.3 Rheumatoid nodule
0.000 0.982 0.018
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.982 0.018
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.018 0.982 0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.018 0.982 0.000
N51.0 Disorders of prostate in diseases classified elsewhere
0.018 0.982 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.982 0.018
N41.1 Chronic prostatitis
0.018 0.982 0.000
M06.4 Inflammatory polyarthropathy
0.000 0.983 0.017
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.983 0.017
E28.2 Polycystic ovarian syndrome
0.000 0.983 0.016
R60.9 Oedema, unspecified
0.000 0.983 0.017
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.016 0.983 0.000
M07.3 Other psoriatic arthropathies
0.000 0.984 0.016
M06.0 Seronegative rheumatoid arthritis
0.000 0.984 0.016
M06.8 Other specified rheumatoid arthritis
0.000 0.984 0.016
M06.2 Rheumatoid bursitis
0.000 0.984 0.016
M06.1 Adult-onset Still's disease
0.000 0.984 0.016
N49.9 Inflammatory disorder of unspecified male genital organ
0.015 0.984 0.000
N49.0 Inflammatory disorders of seminal vesicle
0.015 0.984 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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