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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2523809
log Bayes Factor = 5.11904
Chromosome 6   position 29,849,619  (GRCh37) Explore rs2523809 on Ensembl!
Variant rs2523809 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E10.9 Without complications
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.002 0.998
E03.9 Hypothyroidism, unspecified
0.000 0.002 0.998
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.002 0.998
E06 Thyroiditis
0.000 0.033 0.967
E10.1 With ketoacidosis
0.000 0.052 0.948
E06.3 Autoimmune thyroiditis
0.000 0.069 0.931
E11 Non-insulin-dependent diabetes mellitus
0.000 0.070 0.930
E10.3 With ophthalmic complications
0.000 0.085 0.915
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.112 0.888
E10.4 With neurological complications
0.000 0.140 0.860
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.146 0.854
E04 Other non-toxic goitre
0.000 0.148 0.852
E10.2 With renal complications
0.000 0.158 0.842
E06.9 Thyroiditis, unspecified
0.000 0.207 0.793
E11.2 With renal complications
0.000 0.210 0.790
E70-E90 Metabolic disorders
0.000 0.218 0.782
E11.3 With ophthalmic complications
0.000 0.218 0.782
E10.5 With peripheral circulatory complications
0.000 0.219 0.781
E03.8 Other specified hypothyroidism
0.000 0.220 0.780
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.221 0.779
E04.2 Non-toxic multinodular goitre
0.000 0.222 0.778
E11.1 With ketoacidosis
0.000 0.232 0.768
E40-E46 Malnutrition
0.000 0.232 0.768
E89.0 Postprocedural hypothyroidism
0.000 0.245 0.755
E07 Other disorders of thyroid
0.000 0.246 0.753
E10.0 With coma
0.000 0.247 0.753
E11.8 With unspecified complications
0.000 0.247 0.753
E14 Unspecified diabetes mellitus
0.000 0.255 0.745
E10.8 With unspecified complications
0.000 0.256 0.744
E11.0 With coma
0.000 0.262 0.738
E89.2 Postprocedural hypoparathyroidism
0.000 0.265 0.735
E11.4 With neurological complications
0.000 0.268 0.732
E13 Other specified diabetes mellitus
0.000 0.278 0.722
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
E11.6 With other specified complications
0.000 0.286 0.714
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.292 0.707
E10.6 With other specified complications
0.000 0.295 0.705
E04.1 Non-toxic single thyroid nodule
0.000 0.305 0.695
E06.5 Other chronic thyroiditis
0.000 0.306 0.693
E06.4 Drug-induced thyroiditis
0.000 0.306 0.693
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.306 0.693
E06.1 Subacute thyroiditis
0.000 0.306 0.693
E06.0 Acute thyroiditis
0.000 0.306 0.693
E11.7 With multiple complications
0.000 0.333 0.667
E65-E68 Obesity and other hyperalimentation
0.000 0.335 0.665
E11.5 With peripheral circulatory complications
0.000 0.336 0.664
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.336 0.664
E04.0 Non-toxic diffuse goitre
0.000 0.340 0.660
E89.3 Postprocedural hypopituitarism
0.000 0.352 0.648
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.359 0.641
E05.5 Thyroid crisis or storm
0.000 0.363 0.637
E05.4 Thyrotoxicosis factitia
0.000 0.363 0.637
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.363 0.637
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.363 0.637
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.384 0.616
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.387 0.613
E04.8 Other specified non-toxic goitre
0.000 0.389 0.611
E14.3 With ophthalmic complications
0.000 0.394 0.606
E46 Unspecified protein-energy malnutrition
0.000 0.397 0.603
E80.4 Gilbert's syndrome
0.000 0.400 0.600
E73 Lactose intolerance
0.000 0.401 0.599
E05.9 Thyrotoxicosis, unspecified
0.000 0.404 0.596
E14.9 Without complications
0.000 0.422 0.578
E85 Amyloidosis
0.000 0.428 0.572
E07.8 Other specified disorders of thyroid
0.000 0.438 0.562
E84 Cystic fibrosis
0.000 0.439 0.561
E79 Disorders of purine and pyrimidine metabolism
0.000 0.439 0.561
E77 Disorders of glycoprotein metabolism
0.000 0.439 0.561
E76 Disorders of glycosaminoglycan metabolism
0.000 0.439 0.561
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.439 0.561
E72 Other disorders of amino-acid metabolism
0.000 0.439 0.561
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.439 0.561
E70 Disorders of aromatic amino-acid metabolism
0.000 0.439 0.561
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.439 0.561
E03.1 Congenital hypothyroidism without goitre
0.000 0.440 0.559
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.442 0.558
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.442 0.558
E89.5 Postprocedural testicular hypofunction
0.000 0.442 0.558
E89.4 Postprocedural ovarian failure
0.000 0.442 0.558
E89.1 Postprocedural hypoinsulinaemia
0.000 0.442 0.558
E07.9 Disorder of thyroid, unspecified
0.000 0.442 0.558
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.449 0.551
E45 Retarded development following protein-energy malnutrition
0.000 0.449 0.551
E43 Unspecified severe protein-energy malnutrition
0.000 0.449 0.551
E42 Marasmic kwashiorkor
0.000 0.449 0.551
E41 Nutritional marasmus
0.000 0.449 0.551
E40 Kwashiorkor
0.000 0.449 0.551
E88 Other metabolic disorders
0.000 0.451 0.549
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.456 0.544
E07.1 Dyshormogenetic goitre
0.000 0.460 0.540
E07.0 Hypersecretion of calcitonin
0.000 0.460 0.540
M06.9 Rheumatoid arthritis, unspecified
0.000 0.463 0.537
E14.8 With unspecified complications
0.000 0.465 0.534
E14.7 With multiple complications
0.000 0.465 0.534
E14.6 With other specified complications
0.000 0.465 0.534
E14.5 With peripheral circulatory complications
0.000 0.465 0.534
E14.2 Withrenal complications
0.000 0.465 0.534
E14.1 With ketoacidosis
0.000 0.465 0.534
E14.0 With coma
0.000 0.465 0.534
E13.9 Without complications
0.000 0.476 0.524
E13.8 With unspecified complications
0.000 0.482 0.518
E13.7 With multiple complications
0.000 0.482 0.518
E13.6 With other specified complications
0.000 0.482 0.518
E13.5 With peripheral circulatory complications
0.000 0.482 0.518
E13.4 With neurological complications
0.000 0.482 0.518
E13.3 With ophthalmic complications
0.000 0.482 0.518
E13.2 With renal complications
0.000 0.482 0.518
E13.1 With ketoacidosis
0.000 0.482 0.518
E13.0 With coma
0.000 0.482 0.518
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.500 0.500
E66 Obesity
0.000 0.507 0.493
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.512 0.488
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.513 0.487
E67 Other hyperalimentation
0.000 0.523 0.477
E68 Sequelae of hyperalimentation
0.000 0.523 0.477
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.524 0.476
E80.6 Other disorders of bilirubin metabolism
0.000 0.524 0.476
E80.5 Crigler-Najjar syndrome
0.000 0.524 0.476
E80.3 Defects of catalase and peroxydase
0.000 0.524 0.476
E80.1 Porphyria cutanea tarda
0.000 0.524 0.476
E80.0 Hereditary erythropoietic porphyria
0.000 0.524 0.476
E74 Other disorders of carbohydrate metabolism
0.000 0.530 0.470
E73.9 Lactose intolerance, unspecified
0.000 0.532 0.468
E50-E64 Other nutritional deficiencies
0.000 0.534 0.466
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.534 0.465
E15 Nondiabetic hypoglycaemic coma
0.000 0.540 0.460
D50 Iron deficiency anaemia
0.000 0.546 0.454
E66.8 Other obesity
0.000 0.547 0.453
E85.4 Organ-limited amyloidosis
0.000 0.553 0.447
D50.8 Other iron deficiency anaemias
0.000 0.554 0.446
D50.9 Iron deficiency anaemia, unspecified
0.000 0.554 0.446
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.561 0.439
E05.8 Other thyrotoxicosis
0.001 0.565 0.434
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.570 0.430
E73.8 Other lactose intolerance
0.000 0.570 0.430
E73.1 Secondary lactase deficiency
0.000 0.570 0.430
E73.0 Congenital lactase deficiency
0.000 0.570 0.430
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.573 0.427
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.574 0.426
E80.2 Other porphyria
0.000 0.584 0.416
E85.8 Other amyloidosis
0.000 0.590 0.410
E85.3 Secondary systemic amyloidosis
0.000 0.590 0.410
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.590 0.410
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.590 0.410
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.590 0.410
E65 Localised adiposity
0.000 0.597 0.403
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.598 0.402
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.598 0.402
E70.3 Albinism
0.000 0.598 0.402
E70.2 Disorders of tyrosine metabolism
0.000 0.598 0.402
E70.1 Other hyperphenylalaninaemias
0.000 0.598 0.402
E70.0 Classical phenylketonuria
0.000 0.598 0.402
E71.3 Disorders of fatty-acid metabolism
0.000 0.598 0.402
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.598 0.402
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.598 0.402
E71.0 Maple-syrup-urine disease
0.000 0.598 0.402
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.598 0.402
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.598 0.402
E72.5 Disorders of glycine metabolism
0.000 0.598 0.402
E72.4 Disorders of ornithine metabolism
0.000 0.598 0.402
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.598 0.402
E72.2 Disorders of urea cycle metabolism
0.000 0.598 0.402
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.598 0.402
E72.0 Disorders of amino-acid transport
0.000 0.598 0.402
E75.6 Lipid storage disorder, unspecified
0.000 0.598 0.402
E75.5 Other lipid storage disorders
0.000 0.598 0.402
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.598 0.402
E75.3 Sphingolipidosis, unspecified
0.000 0.598 0.402
E75.2 Other sphingolipidosis
0.000 0.598 0.402
E75.1 Other gangliosidosis
0.000 0.598 0.402
E75.0 GM2 gangliosidosis
0.000 0.598 0.402
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.598 0.402
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.598 0.402
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.598 0.402
E76.2 Other mucopolysaccharidoses
0.000 0.598 0.402
E76.1 Mucopolysaccharidosis, type II
0.000 0.598 0.402
E76.0 Mucopolysaccharidosis, type I
0.000 0.598 0.402
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.598 0.402
E77.8 Other disorders of glycoprotein metabolism
0.000 0.598 0.402
E77.1 Defects in glycoprotein degradation
0.000 0.598 0.402
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.598 0.402
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.598 0.402
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.598 0.402
E79.1 Lesch-Nyhan syndrome
0.000 0.598 0.402
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.598 0.402
E84.9 Cystic fibrosis, unspecified
0.000 0.598 0.402
E84.8 Cystic fibrosis with other manifestations
0.000 0.598 0.402
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.598 0.402
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.598 0.402
E14.4 With neurological complications
0.000 0.600 0.399
E44.1 Mild protein-energy malnutrition
0.000 0.605 0.395
E44.0 Moderate protein-energy malnutrition
0.000 0.605 0.395
E88.9 Metabolic disorder, unspecified
0.000 0.606 0.394
E88.8 Other specified metabolic disorders
0.000 0.606 0.394
E88.3 Tumour lysis syndrome
0.000 0.606 0.394
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.606 0.394
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.606 0.394
E20-E35 Disorders of other endocrine glands
0.000 0.608 0.392
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.613 0.387
E16 Other disorders of pancreatic internal secretion
0.000 0.614 0.386
D50-D53 Nutritional anaemias
0.000 0.621 0.379
E85.9 Amyloidosis, unspecified
0.000 0.623 0.377
D51 Vitamin B12 deficiency anaemia
0.000 0.638 0.362
E53 Deficiency of other B group vitamins
0.000 0.642 0.358
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.646 0.354
E66.1 Drug-induced obesity
0.000 0.646 0.354
M06 Other rheumatoid arthritis
0.000 0.651 0.349
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.657 0.343
E67.8 Other specified hyperalimentation
0.000 0.658 0.342
E67.3 Hypervitaminosis D
0.000 0.658 0.342
E67.2 Megavitamin-B6 syndrome
0.000 0.658 0.342
E67.1 Hypercarotenaemia
0.000 0.658 0.342
E67.0 Hypervitaminosis A
0.000 0.658 0.342
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.663 0.337
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.663 0.337
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.663 0.337
E74.2 Disorders of galactose metabolism
0.000 0.663 0.337
E74.1 Disorders of fructose metabolism
0.000 0.663 0.337
E74.0 Glycogen storage disease
0.000 0.663 0.337
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.664 0.336
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.666 0.334
E63 Other nutritional deficiencies
0.000 0.666 0.334
E56 Other vitamin deficiencies
0.000 0.666 0.334
E51 Thiamine deficiency
0.000 0.666 0.334
E50 Vitamin A deficiency
0.000 0.666 0.334
E60 Dietary zinc deficiency
0.000 0.666 0.334
E59 Dietary selenium deficiency
0.000 0.666 0.334
E54 Ascorbic acid deficiency
0.000 0.666 0.334
E52 Niacin deficiency [pellagra]
0.000 0.666 0.334
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.669 0.330
D50.1 Sideropenic dysphagia
0.000 0.674 0.325
E88.2 Lipomatosis, not elsewhere classified
0.000 0.687 0.313
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.689 0.311
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.691 0.309
E66.0 Obesity due to excess calories
0.000 0.698 0.302
E24 Cushing's syndrome
0.000 0.704 0.296
D52 Folate deficiency anaemia
0.000 0.706 0.294
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.707 0.293
M06.4 Inflammatory polyarthropathy
0.000 0.709 0.291
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.719 0.281
E32 Diseases of thymus
0.000 0.719 0.281
E31 Polyglandular dysfunction
0.000 0.719 0.281
E30 Disorders of puberty, not elsewhere classified
0.000 0.719 0.281
E25 Adrenogenital disorders
0.000 0.719 0.281
E53.8 Deficiency of other specified B group vitamins
0.000 0.719 0.281
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.723 0.277
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.723 0.277
E16.4 Abnormal secretion of gastrin
0.000 0.723 0.277
E16.3 Increased secretion of glucagon
0.000 0.723 0.277
E20 Hypoparathyroidism
0.000 0.723 0.276
E34 Other endocrine disorders
0.000 0.724 0.276
E55 Vitamin D deficiency
0.000 0.727 0.273
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.730 0.270
E58 Dietary calcium deficiency
0.000 0.732 0.268
E16.2 Hypoglycaemia, unspecified
0.000 0.735 0.265
M05-M14 Inflammatory polyarthropathies
0.000 0.735 0.265
E26 Hyperaldosteronism
0.000 0.736 0.264
E16.1 Other hypoglycaemia
0.000 0.739 0.261
E22 Hyperfunction of pituitary gland
0.000 0.740 0.259
D53 Other nutritional anaemias
0.000 0.741 0.259
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.741 0.259
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.741 0.259
D51.2 Transcobalamin II deficiency
0.000 0.741 0.259
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.741 0.259
E27 Other disorders of adrenal gland
0.000 0.741 0.259
E29 Testicular dysfunction
0.000 0.743 0.257
E53.9 Vitamin B deficiency, unspecified
0.000 0.743 0.257
E53.1 Pyridoxine deficiency
0.000 0.743 0.257
E53.0 Riboflavin deficiency
0.000 0.743 0.257
E61 Deficiency of other nutrient elements
0.000 0.745 0.255
M06.8 Other specified rheumatoid arthritis
0.000 0.750 0.250
M06.2 Rheumatoid bursitis
0.000 0.750 0.250
M06.1 Adult-onset Still's disease
0.000 0.750 0.250
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.754 0.245
M05 Seropositive rheumatoid arthritis
0.000 0.754 0.246
E28 Ovarian dysfunction
0.000 0.756 0.244
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.759 0.241
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.759 0.241
E50.9 Vitamin A deficiency, unspecified
0.000 0.760 0.240
E50.8 Other manifestations of vitamin A deficiency
0.000 0.760 0.240
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.760 0.240
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.760 0.240
E50.5 Vitamin A deficiency with night blindness
0.000 0.760 0.240
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.760 0.240
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.760 0.240
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.760 0.240
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.760 0.240
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.760 0.240
E51.9 Thiamine deficiency, unspecified
0.000 0.760 0.240
E51.8 Other manifestations of thiamine deficiency
0.000 0.760 0.240
E51.2 Wernicke's encephalopathy
0.000 0.760 0.240
E51.1 Beriberi
0.000 0.760 0.240
E56.9 Vitamin deficiency, unspecified
0.000 0.760 0.240
E56.8 Deficiency of other vitamins
0.000 0.760 0.240
E56.1 Deficiency of vitamin K
0.000 0.760 0.240
E56.0 Deficiency of vitamin E
0.000 0.760 0.240
E63.9 Nutritional deficiency, unspecified
0.000 0.760 0.240
E63.8 Other specified nutritional deficiencies
0.000 0.760 0.240
E63.1 Imbalance of constituents of food intake
0.000 0.760 0.240
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.760 0.240
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.760 0.240
E64.8 Sequelae of other nutritional deficiencies
0.000 0.760 0.240
E64.3 Sequelae of rickets
0.000 0.760 0.240
E64.2 Sequelae of vitamin C deficiency
0.000 0.760 0.240
E64.1 Sequelae of vitamin A deficiency
0.000 0.760 0.240
E64.0 Sequelae of protein-energy malnutrition
0.000 0.760 0.240
E23 Hypofunction and other disorders of pituitary gland
0.000 0.761 0.239
D52.9 Folate deficiency anaemia, unspecified
0.000 0.766 0.234
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.768 0.232
E78.1 Pure hyperglyceridaemia
0.000 0.771 0.229
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.771 0.229
M07 Psoriatic and enteropathic arthropathies
0.000 0.772 0.228
E24.9 Cushing's syndrome, unspecified
0.000 0.773 0.226
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.777 0.223
E78.6 Lipoprotein deficiency
0.000 0.778 0.222
E78.3 Hyperchylomicronaemia
0.000 0.778 0.222
E27.1 Primary adrenocortical insufficiency
0.000 0.785 0.215
M14 Arthropathies in other diseases classified elsewhere
0.000 0.787 0.213
E21.3 Hyperparathyroidism, unspecified
0.000 0.787 0.212
E24.8 Other Cushing's syndrome
0.000 0.788 0.212
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.788 0.212
E24.3 Ectopic ACTH syndrome
0.000 0.788 0.212
E24.2 Drug-induced Cushing's syndrome
0.000 0.788 0.212
E24.1 Nelson's syndrome
0.000 0.788 0.212
E24.0 Pituitary-dependent Cushing's disease
0.000 0.788 0.212
D52.8 Other folate deficiency anaemias
0.000 0.789 0.211
D52.1 Drug-induced folate deficiency anaemia
0.000 0.789 0.211
D52.0 Dietary folate deficiency anaemia
0.000 0.789 0.211
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.791 0.209
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.791 0.209
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.791 0.209
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.791 0.209
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.791 0.209
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.791 0.209
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.791 0.209
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.791 0.209
E78.8 Other disorders of lipoprotein metabolism
0.000 0.793 0.207
E34.9 Endocrine disorder, unspecified
0.000 0.793 0.206
M11 Other crystal arthropathies
0.000 0.795 0.205
M06.3 Rheumatoid nodule
0.000 0.796 0.204
E22.0 Acromegaly and pituitary gigantism
0.000 0.796 0.203
D18.0 Haemangioma, any site
0.203 0.797 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.798 0.202
E25.8 Other adrenogenital disorders
0.000 0.798 0.202
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.798 0.202
E30.9 Disorder of puberty, unspecified
0.000 0.798 0.202
E30.8 Other disorders of puberty
0.000 0.798 0.202
E30.1 Precocious puberty
0.000 0.798 0.202
E30.0 Delayed puberty
0.000 0.798 0.202
E31.9 Polyglandular dysfunction, unspecified
0.000 0.798 0.202
E31.8 Other polyglandular dysfunction
0.000 0.798 0.202
E31.1 Polyglandular hyperfunction
0.000 0.798 0.202
E31.0 Autoimmune polyglandular failure
0.000 0.798 0.202
E32.9 Disease of thymus, unspecified
0.000 0.798 0.202
E32.8 Other diseases of thymus
0.000 0.798 0.202
E32.1 Abscess of thymus
0.000 0.798 0.202
E32.0 Persistent hyperplasia of thymus
0.000 0.798 0.202
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.798 0.202
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.798 0.202
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.798 0.202
M07.3 Other psoriatic arthropathies
0.000 0.799 0.201
E34.0 Carcinoid syndrome
0.000 0.799 0.201
E78.2 Mixed hyperlipidaemia
0.000 0.801 0.199
E78.4 Other hyperlipidaemia
0.000 0.801 0.199
E20.8 Other hypoparathyroidism
0.000 0.802 0.198
E20.1 Pseudohypoparathyroidism
0.000 0.802 0.198
E20.0 Idiopathic hypoparathyroidism
0.000 0.802 0.198
E34.5 Androgen resistance syndrome
0.000 0.802 0.198
E34.4 Constitutional tall stature
0.000 0.802 0.198
E34.3 Short stature, not elsewhere classified
0.000 0.802 0.198
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.802 0.198
E34.1 Other hypersecretion of intestinal hormones
0.000 0.802 0.198
E55.0 Rickets, active
0.000 0.804 0.196
E28.3 Primary ovarian failure
0.000 0.805 0.195
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.806 0.194
E21.4 Other specified disorders of parathyroid gland
0.000 0.806 0.194
E21.2 Other hyperparathyroidism
0.000 0.806 0.194
E04.9 Non-toxic goitre, unspecified
0.001 0.806 0.193
E20.9 Hypoparathyroidism, unspecified
0.000 0.806 0.193
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.807 0.193
E22.1 Hyperprolactinaemia
0.000 0.809 0.191
M12 Other specific arthropathies
0.000 0.810 0.190
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.810 0.190
M08 Juvenile arthritis
0.000 0.810 0.190
E23.6 Other disorders of pituitary gland
0.000 0.810 0.190
E23.2 Diabetes insipidus
0.000 0.810 0.190
E26.9 Hyperaldosteronism, unspecified
0.000 0.811 0.189
E26.8 Other hyperaldosteronism
0.000 0.811 0.189
E26.1 Secondary hyperaldosteronism
0.000 0.811 0.189
E66.9 Obesity, unspecified
0.000 0.813 0.187
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.814 0.186
E22.8 Other hyperfunction of pituitary gland
0.000 0.814 0.186
D53.8 Other specified nutritional anaemias
0.000 0.814 0.186
D53.2 Scorbutic anaemia
0.000 0.814 0.186
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.814 0.186
D53.0 Protein deficiency anaemia
0.000 0.814 0.186
E27.5 Adrenomedullary hyperfunction
0.000 0.814 0.186
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.814 0.186
E27.0 Other adrenocortical overactivity
0.000 0.814 0.186
E21.0 Primary hyperparathyroidism
0.000 0.814 0.186
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.815 0.185
E29.9 Testicular dysfunction, unspecified
0.000 0.815 0.184
E29.8 Other testicular dysfunction
0.000 0.815 0.184
E29.0 Testicular hyperfunction
0.000 0.815 0.184
E61.9 Deficiency of nutrient element, unspecified
0.000 0.817 0.183
E61.8 Deficiency of other specified nutrient elements
0.000 0.817 0.183
E61.7 Deficiency of multiple nutrient elements
0.000 0.817 0.183
E61.6 Vanadium deficiency
0.000 0.817 0.183
E61.5 Molybdenum deficiency
0.000 0.817 0.183
E61.4 Chromium deficiency
0.000 0.817 0.183
E61.3 Manganese deficiency
0.000 0.817 0.183
E61.0 Copper deficiency
0.000 0.817 0.183
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.820 0.179
M06.18 Adult-onset Still's disease (Other)
0.000 0.820 0.179
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.820 0.179
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.820 0.179
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.820 0.179
M06.14 Adult-onset Still's disease (Hand)
0.000 0.820 0.179
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.820 0.179
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.820 0.179
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.820 0.179
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.820 0.179
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.820 0.179
M06.28 Rheumatoid bursitis (Other)
0.000 0.820 0.179
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.820 0.179
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.820 0.179
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.820 0.179
M06.24 Rheumatoid bursitis (Hand)
0.000 0.820 0.179
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.820 0.179
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.820 0.179
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.820 0.179
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.820 0.179
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.820 0.179
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.820 0.179
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.820 0.179
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.820 0.179
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.820 0.179
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.820 0.179
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.820 0.179
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.820 0.179
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.820 0.179
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.820 0.179
E34.8 Other specified endocrine disorders
0.000 0.822 0.178
M05.8 Other seropositive rheumatoid arthritis
0.000 0.823 0.176
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.823 0.176
M05.2 Rheumatoid vasculitis
0.000 0.823 0.176
M05.1 Rheumatoid lung disease
0.000 0.823 0.176
M05.0 Felty's syndrome
0.000 0.823 0.176
M14.6 Neuropathic arthropathy
0.000 0.824 0.176
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.824 0.176
E28.9 Ovarian dysfunction, unspecified
0.000 0.825 0.175
E28.8 Other ovarian dysfunction
0.000 0.825 0.175
E28.1 Androgen excess
0.000 0.825 0.175
E28.0 Oestrogen excess
0.000 0.825 0.175
D53.9 Nutritional anaemia, unspecified
0.000 0.826 0.174
E27.2 Addisonian crisis
0.000 0.827 0.173
E26.0 Primary hyperaldosteronism
0.000 0.828 0.172
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.829 0.171
E23.1 Drug-induced hypopituitarism
0.000 0.829 0.171
E27.9 Disorder of adrenal gland, unspecified
0.000 0.831 0.169
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.833 0.167
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.833 0.167
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.833 0.167
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.833 0.167
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.833 0.167
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.833 0.167
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.833 0.167
E87.6 Hypokalaemia
0.000 0.833 0.167
M06.0 Seronegative rheumatoid arthritis
0.000 0.834 0.165
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.834 0.166
M07.6 Other enteropathic arthropathies
0.000 0.836 0.163

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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