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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2523873
log Bayes Factor = 78.8429
Chromosome 6   position 31,012,263  (GRCh37) Explore rs2523873 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
L40 Psoriasis
0.000 0.001 0.999
L40.5 Arthropathic psoriasis
0.000 0.002 0.998
C61 Malignant neoplasm of prostate
0.994 0.006 0.000
E07 Other disorders of thyroid
0.000 0.022 0.978
E07.9 Disorder of thyroid, unspecified
0.000 0.038 0.962
E83.1 Disorders of iron metabolism
0.929 0.071 0.000
E03.8 Other specified hypothyroidism
0.000 0.091 0.909
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.117 0.883
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.118 0.882
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.118 0.882
C83.3 Large cell (diffuse)
0.000 0.119 0.881
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.122 0.878
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.123 0.877
L40.0 Psoriasis vulgaris
0.000 0.129 0.871
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.136 0.864
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.143 0.857
C85.1 B-cell lymphoma, unspecified
0.000 0.155 0.845
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.189 0.811
C81 Hodgkin's disease
0.000 0.200 0.800
L40.8 Other psoriasis
0.000 0.202 0.798
L40.1 Generalised pustular psoriasis
0.000 0.213 0.787
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.234 0.765
E06 Thyroiditis
0.000 0.241 0.759
C82.3 Follicular lymphoma grade IIIa
0.000 0.242 0.758
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.247 0.753
C82.2 Large cell, follicular
0.000 0.263 0.737
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
C83.7 Burkitt's tumour
0.000 0.287 0.713
E07.8 Other specified disorders of thyroid
0.000 0.288 0.712
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.292 0.708
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.293 0.707
E07.1 Dyshormogenetic goitre
0.000 0.299 0.701
E07.0 Hypersecretion of calcitonin
0.000 0.299 0.701
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.308 0.692
C81.9 Hodgkin's disease, unspecified
0.000 0.323 0.677
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.325 0.675
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.345 0.655
K90 Intestinal malabsorption
0.000 0.350 0.650
C81.1 Nodular sclerosis
0.000 0.355 0.645
C82.0 Small cleaved cell, follicular
0.000 0.357 0.643
E06.3 Autoimmune thyroiditis
0.000 0.361 0.639
L40.4 Guttate psoriasis
0.000 0.362 0.637
C85.0 Lymphosarcoma
0.000 0.367 0.633
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.368 0.632
C82.6 Cutaneous follicle centre lymphoma
0.000 0.368 0.632
C82.5 Diffuse follicle centre lymphoma
0.000 0.368 0.632
C83.6 Undifferentiated (diffuse)
0.000 0.371 0.629
C83.4 Immunoblastic (diffuse)
0.000 0.371 0.629
C83.2 Mixed small and large cell (diffuse)
0.000 0.371 0.629
C86 Other specified types of T/NK-cell lymphoma
0.000 0.373 0.626
C81.2 Mixed cellularity
0.000 0.381 0.619
C84.5 Other and unspecified T-cell lymphomas
0.000 0.385 0.615
C81.0 Lymphocytic predominance
0.000 0.386 0.614
C82.4 Follicular lymphoma grade IIIb
0.000 0.387 0.612
E03.1 Congenital hypothyroidism without goitre
0.000 0.389 0.611
L40.3 Pustulosis palmaris et plantaris
0.000 0.399 0.601
C94 Other leukaemias of specified cell type
0.000 0.409 0.591
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.416 0.583
E05.8 Other thyrotoxicosis
0.000 0.419 0.581
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.426 0.574
C81.3 Lymphocytic depletion
0.000 0.426 0.574
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.426 0.573
C95 Leukaemia of unspecified cell type
0.000 0.433 0.567
C81.7 Other Hodgkin's disease
0.000 0.438 0.562
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.444 0.556
C93 Monocytic leukaemia
0.000 0.444 0.555
C83.1 Small cleaved cell (diffuse)
0.000 0.451 0.549
C83.5 Lymphoblastic (diffuse)
0.000 0.451 0.549
E06.5 Other chronic thyroiditis
0.000 0.456 0.544
E06.4 Drug-induced thyroiditis
0.000 0.456 0.544
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.456 0.544
E06.0 Acute thyroiditis
0.000 0.456 0.544
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.456 0.544
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.473 0.527
K90.9 Intestinal malabsorption, unspecified
0.000 0.483 0.517
C84.0 Mycosis fungoides
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.492 0.508
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.492 0.508
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.492 0.508
C84.3 Lymphoepithelioid lymphoma
0.000 0.492 0.508
C84.2 T-zone lymphoma
0.000 0.492 0.508
C84.1 Sezary's diease
0.000 0.492 0.508
E06.9 Thyroiditis, unspecified
0.000 0.498 0.502
E06.1 Subacute thyroiditis
0.000 0.500 0.499
C88 Malignant immunoproliferative diseases
0.000 0.516 0.484
K90.8 Other intestinal malabsorption
0.000 0.532 0.468
K90.3 Pancreatic steatorrhoea
0.000 0.534 0.466
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.534 0.466
K90.1 Tropical sprue
0.000 0.534 0.466
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.546 0.453
C96.8 Histiocytic sarcoma
0.000 0.546 0.453
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.546 0.453
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.546 0.453
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.546 0.453
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.546 0.453
C96.3 True histiocytic lymphoma
0.000 0.546 0.453
C96.2 Malignant mast cell tumour
0.000 0.546 0.453
C96.1 Malignant histiocytosis
0.000 0.546 0.453
C96.0 Letterer-Siwe disease
0.000 0.546 0.453
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.551 0.449
C86.4 Blastic NK-cell lymphoma
0.000 0.551 0.449
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.551 0.449
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.551 0.449
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.551 0.449
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.551 0.449
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.556 0.443
C95.9 Leukaemia, unspecified
0.000 0.557 0.443
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.574 0.426
C94.7 Other specified leukaemias
0.000 0.576 0.424
C94.5 Acute myelofibrosis
0.000 0.576 0.424
C94.4 Acute panmyelosis
0.000 0.576 0.424
C94.3 Mast cell leukaemia
0.000 0.576 0.424
C94.2 Acute megakaryoblastic leukaemia
0.000 0.576 0.424
C94.1 Chronic erythraemia
0.000 0.576 0.424
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.576 0.424
C95.7 Other leukaemia of unspecified cell type
0.000 0.593 0.407
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.593 0.407
C84.4 Peripheral T-cell lymphoma
0.000 0.597 0.403
C93.9 Monocytic leukaemia, unspecified
0.000 0.601 0.398
C93.7 Other monocytic leukaemia
0.000 0.601 0.398
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.601 0.398
C93.2 Subacute monocytic leukaemia
0.000 0.601 0.398
C93.0 Acute monocytic leukaemia
0.000 0.601 0.398
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.615 0.385
C60-C63 Malignant neoplasms of male genital organs
0.385 0.615 0.000
L40-L45 Papulosquamous disorders
0.000 0.616 0.384
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.617 0.383
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.653 0.347
C88.7 Other malignant immunoproliferative diseases
0.000 0.653 0.347
C88.3 Immunoproliferative small intestinal disease
0.000 0.653 0.347
C88.2 Gamma heavy chain disease
0.000 0.653 0.347
C88.1 Alpha heavy chain disease
0.000 0.653 0.347
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.653 0.347
C90 Multiple myeloma and malignant plasma cell neoplasms
0.001 0.654 0.345
C93.1 Chronic monocytic leukaemia
0.000 0.678 0.321
C95.0 Acute leukaemia of unspecified cell type
0.001 0.688 0.312
C60 Malignant neoplasm of penis
0.309 0.691 0.000
C91 Lymphoid leukaemia
0.000 0.692 0.307
C83.0 Small cell (diffuse)
0.001 0.706 0.294
C63 Malignant neoplasm of other and unspecified male genital organs
0.283 0.717 0.000
L42 Pityriasis rosea
0.000 0.719 0.281
L43 Lichen planus
0.000 0.720 0.280
L44 Other papulosquamous disorders
0.000 0.725 0.275
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.725 0.275
C91.9 Lymphoid leukaemia, unspecified
0.000 0.729 0.271
C90.1 Plasma cell leukaemia
0.001 0.730 0.270
C90.3 Solitary plasmacytoma
0.001 0.744 0.255
L41 Parapsoriasis
0.000 0.755 0.245
C60.1 Glans penis
0.241 0.759 0.000
C60.9 Penis, unspecified
0.236 0.764 0.000
C60.0 Prepuce
0.227 0.773 0.000
C60.8 Overlapping lesion of penis
0.222 0.778 0.000
C60.2 Body of penis
0.222 0.778 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.779 0.221
C91.7 Other lymphoid leukaemia
0.000 0.779 0.221
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.779 0.221
C91.3 Prolymphocytic leukaemia
0.000 0.779 0.221
C91.2 Subacute lymphocytic leukaemia
0.000 0.779 0.221
L43.9 Lichen planus, unspecified
0.000 0.783 0.217
C63.2 Scrotum
0.210 0.790 0.000
C63.9 Male genital organ, unspecified
0.203 0.797 0.000
C63.8 Overlapping lesion of male genital organs
0.203 0.797 0.000
C63.7 Other specified male genital organs
0.203 0.797 0.000
C63.1 Spermatic cord
0.203 0.797 0.000
C63.0 Epididymis
0.203 0.797 0.000
L43.3 Subacute (active) lichen planus
0.000 0.799 0.201
L43.2 Lichenoid drug reaction
0.000 0.799 0.201
L43.1 Bullous lichen planus
0.000 0.799 0.201
L43.0 Hypertrophic lichen planus
0.000 0.799 0.201
C88.0 Waldenstrom's macroglobulinaemia
0.001 0.801 0.198
C91.4 Hairy-cell leukaemia
0.000 0.801 0.199
L44.9 Papulosquamous disorder, unspecified
0.000 0.802 0.197
L44.8 Other specified papulosquamous disorders
0.000 0.802 0.197
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.802 0.197
L44.3 Lichen ruber moniliformis
0.000 0.802 0.197
L44.2 Lichen striatus
0.000 0.802 0.197
L44.1 Lichen nitidus
0.000 0.802 0.197
L44.0 Pityriasis rubra pilaris
0.000 0.802 0.197
C91.5 Adult T-cell leukaemia
0.000 0.806 0.194
C62 Malignant neoplasm of testis
0.193 0.806 0.000
E78.0 Pure hypercholesterolaemia
0.000 0.814 0.186
L43.8 Other lichen planus
0.000 0.815 0.185
C90.2 Plasmacytoma, extramedullary
0.001 0.816 0.183
L41.9 Parapsoriasis, unspecified
0.000 0.824 0.176
L41.8 Other parapsoriasis
0.000 0.824 0.176
L41.5 Retiform parapsoriasis
0.000 0.824 0.176
L41.4 Large plaque parapsoriasis
0.000 0.824 0.176
L41.3 Small plaque parapsoriasis
0.000 0.824 0.176
L41.2 Lymphomatoid papulosis
0.000 0.824 0.176
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.824 0.176
C92 Myeloid leukaemia
0.001 0.831 0.168
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.839 0.161
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.846 0.154
L41.1 Pityriasis lichenoides chronica
0.000 0.854 0.146
E78.8 Other disorders of lipoprotein metabolism
0.000 0.857 0.143
E78.5 Hyperlipidaemia, unspecified
0.000 0.860 0.140
C62.0 Undescended testis
0.139 0.861 0.000
C62.1 Descended testis
0.134 0.866 0.000
E40-E46 Malnutrition
0.000 0.867 0.133
E78.2 Mixed hyperlipidaemia
0.000 0.872 0.128
C92.1 Chronic myeloid leukaemia
0.001 0.873 0.127
E70-E90 Metabolic disorders
0.003 0.873 0.124
E78.6 Lipoprotein deficiency
0.000 0.875 0.125
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.001 0.879 0.120
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.001 0.879 0.120
C92.3 Myeloid sarcoma
0.001 0.879 0.120
C92.2 Subacute myeloid leukaemia
0.001 0.879 0.120
E46 Unspecified protein-energy malnutrition
0.000 0.881 0.119
E20-E35 Disorders of other endocrine glands
0.000 0.882 0.118
E78.4 Other hyperlipidaemia
0.000 0.883 0.117
C91.0 Acute lymphoblastic leukaemia
0.001 0.885 0.114
E83 Disorders of mineral metabolism
0.095 0.886 0.020
E24 Cushing's syndrome
0.000 0.887 0.113
C92.5 Acute myelomonocytic leukaemia
0.001 0.887 0.112
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.888 0.111
E23 Hypofunction and other disorders of pituitary gland
0.000 0.891 0.109
E78.1 Pure hyperglyceridaemia
0.000 0.892 0.108
E24.9 Cushing's syndrome, unspecified
0.000 0.897 0.103
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.899 0.101
C92.9 Myeloid leukaemia, unspecified
0.001 0.899 0.100
E89.0 Postprocedural hypothyroidism
0.000 0.900 0.100
K60.2 Anal fissure, unspecified
0.000 0.901 0.099
E78.3 Hyperchylomicronaemia
0.000 0.902 0.098
E28 Ovarian dysfunction
0.000 0.903 0.097
E21.3 Hyperparathyroidism, unspecified
0.000 0.904 0.096
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.904 0.096
E45 Retarded development following protein-energy malnutrition
0.000 0.904 0.096
E43 Unspecified severe protein-energy malnutrition
0.000 0.904 0.096
E42 Marasmic kwashiorkor
0.000 0.904 0.096
E41 Nutritional marasmus
0.000 0.904 0.096
E40 Kwashiorkor
0.000 0.904 0.096
E24.0 Pituitary-dependent Cushing's disease
0.000 0.904 0.095
E23.7 Disorder of pituitary gland, unspecified
0.000 0.905 0.095
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.002 0.905 0.093
C92.4 Acute promyelocytic leukaemia
0.001 0.906 0.093
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.906 0.094
C92.7 Other myeloid leukaemia
0.001 0.907 0.092
E23.2 Diabetes insipidus
0.000 0.908 0.092
E89.4 Postprocedural ovarian failure
0.000 0.909 0.091
E77 Disorders of glycoprotein metabolism
0.002 0.909 0.089
E76 Disorders of glycosaminoglycan metabolism
0.002 0.909 0.089
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.002 0.909 0.089
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.002 0.909 0.089
E24.2 Drug-induced Cushing's syndrome
0.000 0.909 0.091
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.909 0.090
E72 Other disorders of amino-acid metabolism
0.002 0.910 0.088
E74 Other disorders of carbohydrate metabolism
0.002 0.911 0.087
E70 Disorders of aromatic amino-acid metabolism
0.002 0.911 0.087
E89.2 Postprocedural hypoparathyroidism
0.000 0.911 0.088
E23.6 Other disorders of pituitary gland
0.000 0.912 0.087
E25 Adrenogenital disorders
0.000 0.913 0.087
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.087 0.913 0.000
E73 Lactose intolerance
0.002 0.914 0.085
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.915 0.085
E32 Diseases of thymus
0.000 0.915 0.085
E30 Disorders of puberty, not elsewhere classified
0.000 0.915 0.085
E28.3 Primary ovarian failure
0.000 0.916 0.084
E31 Polyglandular dysfunction
0.000 0.917 0.082
E83.9 Disorder of mineral metabolism, unspecified
0.068 0.918 0.014
E83.8 Other disorders of mineral metabolism
0.068 0.918 0.014
E83.2 Disorders of zinc metabolism
0.068 0.918 0.014
E83.0 Disorders of copper metabolism
0.068 0.918 0.014
E24.8 Other Cushing's syndrome
0.000 0.918 0.081
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.918 0.081
E24.3 Ectopic ACTH syndrome
0.000 0.918 0.081
E24.1 Nelson's syndrome
0.000 0.918 0.081
E84 Cystic fibrosis
0.002 0.919 0.079
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.920 0.080
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.920 0.080
E89.5 Postprocedural testicular hypofunction
0.000 0.920 0.080
E89.3 Postprocedural hypopituitarism
0.000 0.921 0.079
E79 Disorders of purine and pyrimidine metabolism
0.002 0.921 0.076
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.921 0.078
E23.1 Drug-induced hypopituitarism
0.000 0.921 0.078
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.922 0.078
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.924 0.076
E26 Hyperaldosteronism
0.000 0.924 0.075
K60 Fissure and fistula of anal and rectal regions
0.000 0.926 0.074
E83.3 Disorders of phosphorus metabolism
0.065 0.926 0.008
E75.5 Other lipid storage disorders
0.001 0.928 0.071
E80.6 Other disorders of bilirubin metabolism
0.001 0.928 0.071
E04 Other non-toxic goitre
0.001 0.929 0.071
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.001 0.929 0.071
E23.0 Hypopituitarism
0.000 0.929 0.071
E89.1 Postprocedural hypoinsulinaemia
0.001 0.929 0.070
E28.9 Ovarian dysfunction, unspecified
0.000 0.930 0.070
E28.8 Other ovarian dysfunction
0.000 0.930 0.070
E28.1 Androgen excess
0.000 0.930 0.070
E28.0 Oestrogen excess
0.000 0.930 0.070
E44.1 Mild protein-energy malnutrition
0.000 0.931 0.069
E44.0 Moderate protein-energy malnutrition
0.000 0.931 0.069
E75.6 Lipid storage disorder, unspecified
0.002 0.932 0.067
E75.4 Neuronal ceroid lipofuscinosis
0.002 0.932 0.067
E75.3 Sphingolipidosis, unspecified
0.002 0.932 0.067
E75.2 Other sphingolipidosis
0.002 0.932 0.067
E75.1 Other gangliosidosis
0.002 0.932 0.067
E75.0 GM2 gangliosidosis
0.002 0.932 0.067
E21.2 Other hyperparathyroidism
0.000 0.932 0.068
E80.2 Other porphyria
0.001 0.932 0.067
E15 Nondiabetic hypoglycaemic coma
0.000 0.932 0.067
C62.9 Testis, unspecified
0.067 0.932 0.000
K60.3 Anal fistula
0.000 0.933 0.067
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.934 0.065
E71.3 Disorders of fatty-acid metabolism
0.002 0.934 0.064
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.002 0.934 0.064
E71.1 Other disorders of branched-chain amino-acid metabolism
0.002 0.934 0.064
E71.0 Maple-syrup-urine disease
0.002 0.934 0.064
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.002 0.934 0.064
E76.8 Other disorders of glucosaminoglycan metabolism
0.002 0.934 0.064
E76.3 Mucopolysaccharidosis, unspecified
0.002 0.934 0.064
E76.2 Other mucopolysaccharidoses
0.002 0.934 0.064
E76.1 Mucopolysaccharidosis, type II
0.002 0.934 0.064
E76.0 Mucopolysaccharidosis, type I
0.002 0.934 0.064
E77.9 Disorder of glycoprotein metabolism, unspecified
0.002 0.934 0.064
E77.8 Other disorders of glycoprotein metabolism
0.002 0.934 0.064
E77.1 Defects in glycoprotein degradation
0.002 0.934 0.064
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.002 0.934 0.064
E28.2 Polycystic ovarian syndrome
0.000 0.935 0.065
E80.7 Disorder of bilirubin metabolism, unspecified
0.001 0.935 0.064
E80.5 Crigler-Najjar syndrome
0.001 0.935 0.064
E80.3 Defects of catalase and peroxydase
0.001 0.935 0.064
E80.0 Hereditary erythropoietic porphyria
0.001 0.935 0.064
E72.9 Disorder of amino-acid metabolism, unspecified
0.002 0.935 0.063
E72.8 Other specified disorders of amino-acid metabolism
0.002 0.935 0.063
E72.5 Disorders of glycine metabolism
0.002 0.935 0.063
E72.4 Disorders of ornithine metabolism
0.002 0.935 0.063
E72.3 Disorders of lysine and hydroxylysine metabolism
0.002 0.935 0.063
E72.2 Disorders of urea cycle metabolism
0.002 0.935 0.063
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.002 0.935 0.063
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.936 0.063
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.936 0.063
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.936 0.063
E74.2 Disorders of galactose metabolism
0.001 0.936 0.063
E74.1 Disorders of fructose metabolism
0.001 0.936 0.063
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.936 0.064
E21.4 Other specified disorders of parathyroid gland
0.000 0.936 0.064
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.002 0.936 0.062
E70.8 Other disorders of aromatic amino-acid metabolism
0.002 0.936 0.062
E70.2 Disorders of tyrosine metabolism
0.002 0.936 0.062
E70.1 Other hyperphenylalaninaemias
0.002 0.936 0.062
E70.0 Classical phenylketonuria
0.002 0.936 0.062
E50-E64 Other nutritional deficiencies
0.000 0.936 0.063
E72.0 Disorders of amino-acid transport
0.002 0.937 0.061
E80.1 Porphyria cutanea tarda
0.001 0.937 0.062
E25.9 Adrenogenital disorder, unspecified
0.000 0.938 0.062
E25.8 Other adrenogenital disorders
0.000 0.938 0.062
H00.1 Chalazion
0.062 0.938 0.000
E73.8 Other lactose intolerance
0.001 0.938 0.061
E73.1 Secondary lactase deficiency
0.001 0.938 0.061
E73.0 Congenital lactase deficiency
0.001 0.938 0.061
E29 Testicular dysfunction
0.000 0.938 0.062
K60.5 Anorectal fistula
0.000 0.938 0.062
E30.9 Disorder of puberty, unspecified
0.000 0.939 0.061
E30.8 Other disorders of puberty
0.000 0.939 0.061
E30.1 Precocious puberty
0.000 0.939 0.061
E30.0 Delayed puberty
0.000 0.939 0.061
E32.9 Disease of thymus, unspecified
0.000 0.939 0.061
E32.8 Other diseases of thymus
0.000 0.939 0.061
E32.1 Abscess of thymus
0.000 0.939 0.061
E32.0 Persistent hyperplasia of thymus
0.000 0.939 0.061
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.939 0.061
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.939 0.061
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.939 0.061
E70.3 Albinism
0.002 0.939 0.060
S72 Fracture of femur
0.061 0.939 0.000
E74.0 Glycogen storage disease
0.002 0.940 0.058
E20 Hypoparathyroidism
0.000 0.940 0.059
E88 Other metabolic disorders
0.002 0.940 0.057
E31.9 Polyglandular dysfunction, unspecified
0.000 0.941 0.059
E31.8 Other polyglandular dysfunction
0.000 0.941 0.059
E31.1 Polyglandular hyperfunction
0.000 0.941 0.059
S72.3 Fracture of shaft of femur
0.059 0.941 0.000
E84.8 Cystic fibrosis with other manifestations
0.002 0.941 0.057
E84.1 Cystic fibrosis with intestinal manifestations
0.002 0.941 0.057
K60.0 Acute anal fissure
0.000 0.942 0.058
E22 Hyperfunction of pituitary gland
0.000 0.942 0.058
E73.9 Lactose intolerance, unspecified
0.001 0.943 0.056
K60.4 Rectal fistula
0.000 0.943 0.057
E10-E14 Diabetes mellitus
0.000 0.943 0.057
E31.0 Autoimmune polyglandular failure
0.000 0.943 0.057
S72.1 Pertrochanteric fracture
0.057 0.943 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.002 0.943 0.055
E79.8 Other disorders of purine and pyrimidine metabolism
0.002 0.943 0.055
E79.1 Lesch-Nyhan syndrome
0.002 0.943 0.055
S72.30 Fracture of shaft of femur (closed)
0.057 0.943 0.000
Z51.3 Blood transfusion without reported diagnosis
0.000 0.944 0.056
S72.2 Subtrochanteric fracture
0.055 0.945 0.000
E80.4 Gilbert's syndrome
0.000 0.945 0.055
S72.9 Fracture of femur, part unspecified
0.055 0.945 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.946 0.054
E26.8 Other hyperaldosteronism
0.000 0.946 0.054
E26.1 Secondary hyperaldosteronism
0.000 0.946 0.054
E84.9 Cystic fibrosis, unspecified
0.002 0.946 0.053
S72.10 Pertrochanteric fracture (closed)
0.054 0.946 0.000
E84.0 Cystic fibrosis with pulmonary manifestations
0.002 0.946 0.052
S72.0 Fracture of neck of femur
0.053 0.947 0.000
S72.20 Subtrochanteric fracture (closed)
0.052 0.948 0.000
E04.8 Other specified non-toxic goitre
0.001 0.949 0.051
E16 Other disorders of pancreatic internal secretion
0.000 0.949 0.051
S72.90 Fracture of femur, part unspecified (closed)
0.051 0.949 0.000
E61 Deficiency of other nutrient elements
0.000 0.949 0.050
E88.8 Other specified metabolic disorders
0.001 0.950 0.049
E65-E68 Obesity and other hyperalimentation
0.000 0.951 0.049
E04.0 Non-toxic diffuse goitre
0.000 0.951 0.049
S72.8 Fractures of other parts of femur
0.049 0.951 0.000
E51 Thiamine deficiency
0.000 0.951 0.049
S72.00 Fracture of neck of femur (closed)
0.048 0.952 0.000
E10.3 With ophthalmic complications
0.000 0.953 0.047
E10 Insulin-dependent diabetes mellitus
0.000 0.953 0.047
E21.0 Primary hyperparathyroidism
0.000 0.953 0.047
E88.2 Lipomatosis, not elsewhere classified
0.001 0.953 0.045
E56 Other vitamin deficiencies
0.000 0.954 0.046
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.954 0.046
E63 Other nutritional deficiencies
0.000 0.954 0.046
E50 Vitamin A deficiency
0.000 0.954 0.046
E60 Dietary zinc deficiency
0.000 0.954 0.046
E59 Dietary selenium deficiency
0.000 0.954 0.046
E52 Niacin deficiency [pellagra]
0.000 0.954 0.046
S72.31 Fracture of shaft of femur (open)
0.046 0.954 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.955 0.045
E26.0 Primary hyperaldosteronism
0.000 0.955 0.045
E29.9 Testicular dysfunction, unspecified
0.000 0.955 0.045
E29.8 Other testicular dysfunction
0.000 0.955 0.045
E29.0 Testicular hyperfunction
0.000 0.955 0.045
S72.7 Multiple fractures of femur
0.044 0.956 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.002 0.956 0.042
H00 Hordeolum and chalazion
0.043 0.957 0.000
E20.1 Pseudohypoparathyroidism
0.000 0.957 0.043
E20.0 Idiopathic hypoparathyroidism
0.000 0.957 0.043
E58 Dietary calcium deficiency
0.000 0.957 0.043
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.958 0.042
E22.8 Other hyperfunction of pituitary gland
0.000 0.958 0.042
C91.1 Chronic lymphocytic leukaemia
0.001 0.958 0.041
E83.4 Disorders of magnesium metabolism
0.032 0.958 0.010
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.959 0.041
E12 Malnutrition-related diabetes mellitus
0.000 0.959 0.041
S72.11 Pertrochanteric fracture (open)
0.041 0.959 0.000
E61.2 Magnesium deficiency
0.000 0.960 0.040
S72.80 Fractures of other parts of femur (closed)
0.040 0.960 0.000
E34 Other endocrine disorders
0.001 0.960 0.039
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.960 0.040
S72.21 Subtrochanteric fracture (open)
0.040 0.960 0.000
K90-K93 Other diseases of the digestive system
0.000 0.960 0.040
H00.0 Hordeolum and other deep inflammation of eyelid
0.040 0.960 0.000
S72.91 Fracture of femur, part unspecified (open)
0.039 0.960 0.000
E54 Ascorbic acid deficiency
0.000 0.961 0.038
E88.3 Tumour lysis syndrome
0.002 0.961 0.037
S72.01 Fracture of neck of femur (open)
0.038 0.961 0.000
E20.8 Other hypoparathyroidism
0.001 0.962 0.038
E51.2 Wernicke's encephalopathy
0.000 0.962 0.038
E61.1 Iron deficiency
0.000 0.963 0.037
E10.8 With unspecified complications
0.000 0.963 0.037
K60.1 Chronic anal fissure
0.000 0.963 0.037
E10.9 Without complications
0.000 0.963 0.037
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.963 0.037
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.963 0.037
E16.4 Abnormal secretion of gastrin
0.000 0.963 0.037
E16.3 Increased secretion of glucagon
0.000 0.963 0.037
E16.1 Other hypoglycaemia
0.000 0.963 0.037
E61.9 Deficiency of nutrient element, unspecified
0.000 0.964 0.036
E61.8 Deficiency of other specified nutrient elements
0.000 0.964 0.036
E61.7 Deficiency of multiple nutrient elements
0.000 0.964 0.036
E61.6 Vanadium deficiency
0.000 0.964 0.036
E61.5 Molybdenum deficiency
0.000 0.964 0.036
E61.4 Chromium deficiency
0.000 0.964 0.036
E61.3 Manganese deficiency
0.000 0.964 0.036
E61.0 Copper deficiency
0.000 0.964 0.036
E10.2 With renal complications
0.000 0.964 0.036
E88.1 Lipodystrophy, not elsewhere classified
0.002 0.964 0.034
E67 Other hyperalimentation
0.000 0.964 0.035
E68 Sequelae of hyperalimentation
0.000 0.964 0.035
S72.81 Fractures of other parts of femur (open)
0.035 0.965 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.965 0.035
E51.8 Other manifestations of thiamine deficiency
0.000 0.965 0.035
E51.1 Beriberi
0.000 0.965 0.035
E13 Other specified diabetes mellitus
0.000 0.965 0.035
S72.4 Fracture of lower end of femur
0.035 0.965 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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