TreeWAS – Variant ID: rs2524043

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.5 Arthropathic psoriasis	0.000	0.001	0.999
L40.9 Psoriasis, unspecified	0.000	0.001	0.999
L40 Psoriasis	0.000	0.001	0.999
L40.0 Psoriasis vulgaris	0.000	0.106	0.894
L40.4 Guttate psoriasis	0.000	0.284	0.716
L40.3 Pustulosis palmaris et plantaris	0.000	0.284	0.716
L40.2 Acrodermatitis continua	0.000	0.284	0.716
L40.1 Generalised pustular psoriasis	0.000	0.284	0.716
L40.8 Other psoriasis	0.000	0.322	0.677
E03 Other hypothyroidism	0.518	0.481	0.001
K90 Intestinal malabsorption	0.000	0.543	0.457
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.428	0.572	0.000
L40-L45 Papulosquamous disorders	0.000	0.626	0.374
E03.5 Myxoedema coma	0.371	0.628	0.001
E03.4 Atrophy of thyroid (acquired)	0.371	0.628	0.001
E03.3 Postinfectious hypothyroidism	0.371	0.628	0.001
E03.1 Congenital hypothyroidism without goitre	0.371	0.628	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.371	0.628	0.001
K90.9 Intestinal malabsorption, unspecified	0.000	0.638	0.362
E03.8 Other specified hypothyroidism	0.349	0.651	0.001
K90.3 Pancreatic steatorrhoea	0.000	0.672	0.328
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.672	0.328
K90.1 Tropical sprue	0.000	0.672	0.328
K90.8 Other intestinal malabsorption	0.000	0.678	0.322
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.699	0.301
L44 Other papulosquamous disorders	0.000	0.732	0.268
L41 Parapsoriasis	0.000	0.732	0.268
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.732	0.268
L42 Pityriasis rosea	0.000	0.742	0.258
L43 Lichen planus	0.000	0.743	0.257
L43.8 Other lichen planus	0.000	0.806	0.194
L41.9 Parapsoriasis, unspecified	0.000	0.808	0.192
L41.8 Other parapsoriasis	0.000	0.808	0.192
L41.5 Retiform parapsoriasis	0.000	0.808	0.192
L41.4 Large plaque parapsoriasis	0.000	0.808	0.192
L41.3 Small plaque parapsoriasis	0.000	0.808	0.192
L41.2 Lymphomatoid papulosis	0.000	0.808	0.192
L41.1 Pityriasis lichenoides chronica	0.000	0.808	0.192
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.808	0.192
L44.9 Papulosquamous disorder, unspecified	0.000	0.808	0.192
L44.8 Other specified papulosquamous disorders	0.000	0.808	0.192
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.808	0.192
L44.3 Lichen ruber moniliformis	0.000	0.808	0.192
L44.2 Lichen striatus	0.000	0.808	0.192
L44.1 Lichen nitidus	0.000	0.808	0.192
L44.0 Pityriasis rubra pilaris	0.000	0.808	0.192
L43.3 Subacute (active) lichen planus	0.000	0.815	0.184
L43.2 Lichenoid drug reaction	0.000	0.815	0.184
L43.1 Bullous lichen planus	0.000	0.815	0.184
L43.0 Hypertrophic lichen planus	0.000	0.815	0.184
L43.9 Lichen planus, unspecified	0.000	0.839	0.161
M25.5 Pain in joint	0.000	0.867	0.133
M25.54 Pain in joint (Hand)	0.000	0.870	0.130
M25.51 Pain in joint (Shoulder region)	0.000	0.871	0.129
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.878	0.122
M25.59 Pain in joint (Site unspecified)	0.000	0.884	0.116
I84.9 Unspecified haemorrhoids without complication	0.111	0.889	0.000
M25.58 Pain in joint (Other)	0.000	0.891	0.109
M25 Other joint disorders, not elsewhere classified	0.000	0.899	0.101
M25.56 Pain in joint (Lower leg)	0.000	0.905	0.095
M25.9 Joint disorder, unspecified	0.000	0.909	0.091
M25.57 Pain in joint (Ankle and foot)	0.000	0.909	0.091
M25.50 Pain in joint (Multiple sites)	0.000	0.911	0.089
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.913	0.087
M25.7 Osteophyte	0.000	0.915	0.085
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.916	0.084
M25.52 Pain in joint (Upper arm)	0.000	0.916	0.083
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.917	0.083
M25.53 Pain in joint (Forearm)	0.000	0.917	0.083
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.926	0.074
M25.77 Osteophyte (Ankle and foot)	0.000	0.927	0.073
M25.2 Flail joint	0.000	0.927	0.073
M25.1 Fistula of joint	0.000	0.927	0.073
M25.71 Osteophyte (Shoulder region)	0.000	0.928	0.072
M25.8 Other specified joint disorders	0.000	0.929	0.071
M25.74 Osteophyte (Hand)	0.000	0.930	0.070
M25.0 Haemarthrosis	0.000	0.931	0.069
M25.84 Other specified joint disorders (Hand)	0.000	0.934	0.066
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.934	0.065
M25.98 Joint disorder, unspecified (Other)	0.000	0.934	0.065
M25.94 Joint disorder, unspecified (Hand)	0.000	0.934	0.065
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.934	0.065
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.934	0.065
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.934	0.065
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.935	0.065
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.936	0.064
M25.3 Other instability of joint	0.000	0.936	0.064
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.936	0.064
M25.76 Osteophyte (Lower leg)	0.000	0.937	0.063
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.937	0.063
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.937	0.063
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.937	0.063
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.937	0.062
M25.79 Osteophyte (Site unspecified)	0.000	0.939	0.061
M25.73 Osteophyte (Forearm)	0.000	0.939	0.061
M25.70 Osteophyte (Multiple sites)	0.000	0.939	0.061
M25.72 Osteophyte (Upper arm)	0.000	0.940	0.060
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.941	0.059
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.942	0.058
M25.86 Other specified joint disorders (Lower leg)	0.000	0.943	0.057
M25.4 Effusion of joint	0.000	0.945	0.055
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.948	0.052
M25.19 Fistula of joint (Site unspecified)	0.000	0.948	0.052
M25.18 Fistula of joint (Other)	0.000	0.948	0.052
M25.17 Fistula of joint (Ankle and foot)	0.000	0.948	0.052
M25.16 Fistula of joint (Lower leg)	0.000	0.948	0.052
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.948	0.052
M25.14 Fistula of joint (Hand)	0.000	0.948	0.052
M25.13 Fistula of joint (Forearm)	0.000	0.948	0.052
M25.12 Fistula of joint (Upper arm)	0.000	0.948	0.052
M25.11 Fistula of joint (Shoulder region)	0.000	0.948	0.052
M25.10 Fistula of joint (Multiple sites)	0.000	0.948	0.052
M25.29 Flail joint (Site unspecified)	0.000	0.948	0.052
M25.28 Flail joint (Other)	0.000	0.948	0.052
M25.27 Flail joint (Ankle and foot)	0.000	0.948	0.052
M25.26 Flail joint (Lower leg)	0.000	0.948	0.052
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.948	0.052
M25.24 Flail joint (Hand)	0.000	0.948	0.052
M25.23 Flail joint (Forearm)	0.000	0.948	0.052
M25.22 Flail joint (Upper arm)	0.000	0.948	0.052
M25.21 Flail joint (Shoulder region)	0.000	0.948	0.052
M25.20 Flail joint (Multiple sites)	0.000	0.948	0.052
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.949	0.051
M25.82 Other specified joint disorders (Upper arm)	0.000	0.949	0.051
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.949	0.051
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.950	0.050
M25.09 Haemarthrosis (Site unspecified)	0.000	0.950	0.050
M25.08 Haemarthrosis (Other)	0.000	0.950	0.050
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.950	0.050
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.950	0.050
M25.04 Haemarthrosis (Hand)	0.000	0.950	0.050
M25.03 Haemarthrosis (Forearm)	0.000	0.950	0.050
M25.02 Haemarthrosis (Upper arm)	0.000	0.950	0.050
M25.01 Haemarthrosis (Shoulder region)	0.000	0.950	0.050
M25.00 Haemarthrosis (Multiple sites)	0.000	0.950	0.050
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.951	0.049
M25.37 Other instability of joint (Ankle and foot)	0.000	0.951	0.048
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.952	0.047
M25.46 Effusion of joint (Lower leg)	0.000	0.952	0.048
M25.36 Other instability of joint (Lower leg)	0.000	0.953	0.047
M25.39 Other instability of joint (Site unspecified)	0.000	0.954	0.046
M25.38 Other instability of joint (Other)	0.000	0.954	0.046
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.954	0.046
M25.32 Other instability of joint (Upper arm)	0.000	0.954	0.046
M25.30 Other instability of joint (Multiple sites)	0.000	0.954	0.046
M25.06 Haemarthrosis (Lower leg)	0.000	0.954	0.046
M25.31 Other instability of joint (Shoulder region)	0.000	0.954	0.045
M25.83 Other specified joint disorders (Forearm)	0.000	0.955	0.045
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.955	0.044
M25.43 Effusion of joint (Forearm)	0.000	0.957	0.043
M25.88 Other specified joint disorders (Other)	0.000	0.959	0.041
M25.34 Other instability of joint (Hand)	0.000	0.959	0.041
M25.33 Other instability of joint (Forearm)	0.000	0.959	0.040
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.960	0.040
M25.49 Effusion of joint (Site unspecified)	0.000	0.961	0.039
M25.48 Effusion of joint (Other)	0.000	0.961	0.039
M25.41 Effusion of joint (Shoulder region)	0.000	0.961	0.039
K90-K93 Other diseases of the digestive system	0.000	0.964	0.036
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.964	0.036
M25.42 Effusion of joint (Upper arm)	0.000	0.965	0.035
M25.44 Effusion of joint (Hand)	0.000	0.966	0.034
E00-E07 Disorders of thyroid gland	0.031	0.966	0.002
M25.40 Effusion of joint (Multiple sites)	0.000	0.966	0.033
M25.78 Osteophyte (Other)	0.000	0.968	0.032
E07 Other disorders of thyroid	0.026	0.973	0.001
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.974	0.026
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.023	0.976	0.002
E00 Congenital iodine-deficiency syndrome	0.023	0.976	0.002
E02 Subclinical iodine-deficiency hypothyroidism	0.023	0.976	0.002
M25.47 Effusion of joint (Ankle and foot)	0.000	0.976	0.024
E07.9 Disorder of thyroid, unspecified	0.023	0.976	0.000
D12.8 Rectum	0.023	0.977	0.000
S64.4 Injury of digital nerve of other finger	0.022	0.978	0.000
E07.1 Dyshormogenetic goitre	0.019	0.980	0.001
E07.0 Hypersecretion of calcitonin	0.019	0.980	0.001
C18.7 Sigmoid colon	0.020	0.980	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.981	0.019
K93.1 Megacolon in Chagas' disease	0.000	0.981	0.019
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.981	0.019
E07.8 Other specified disorders of thyroid	0.017	0.982	0.001
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.016	0.982	0.001
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.016	0.982	0.001
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.016	0.982	0.001
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.016	0.982	0.001
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.016	0.982	0.001
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.016	0.982	0.001
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.016	0.982	0.001
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.016	0.982	0.001
S64 Injury of nerves at wrist and hand level	0.017	0.983	0.000
E06 Thyroiditis	0.013	0.985	0.002
D75 Other diseases of blood and blood-forming organs	0.000	0.985	0.015
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.985	0.015
D70 Agranulocytosis	0.000	0.986	0.014
S64.7 Injury of multiple nerves at wrist and hand level	0.014	0.986	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.013	0.987	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.987	0.013
D75.2 Essential thrombocytosis	0.000	0.987	0.013
S64.2 Injury of radial nerve at wrist and hand level	0.013	0.987	0.000
S60-S69 Injuries to the wrist and hand	0.013	0.987	0.000
S61.0 Open wound of finger(s) without damage to nail	0.013	0.987	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.987	0.013
S64.1 Injury of median nerve at wrist and hand level	0.013	0.987	0.000
S61.8 Open wound of other parts of wrist and hand	0.013	0.987	0.000
D72 Other disorders of white blood cells	0.000	0.987	0.013
D73 Diseases of spleen	0.000	0.987	0.013
S64.9 Injury of unspecified nerve at wrist and hand level	0.012	0.988	0.000
S64.8 Injury of other nerves at wrist and hand level	0.012	0.988	0.000
S61 Open wound of wrist and hand	0.012	0.988	0.000
M20-M25 Other joint disorders	0.000	0.988	0.012
D72.8 Other specified disorders of white blood cells	0.000	0.988	0.012
D73.0 Hyposplenism	0.000	0.988	0.012
S60 Superficial injury of wrist and hand	0.012	0.988	0.000
D75.1 Secondary polycythaemia	0.000	0.988	0.012
C18 Malignant neoplasm of colon	0.012	0.988	0.000
S60.8 Other superficial injuries of wrist and hand	0.011	0.988	0.000
I47.2 Ventricular tachycardia	0.011	0.989	0.000
E66.8 Other obesity	0.000	0.989	0.011
R94.3 Abnormal results of cardiovascular function studies	0.011	0.989	0.000
E06.5 Other chronic thyroiditis	0.009	0.989	0.002
E06.4 Drug-induced thyroiditis	0.009	0.989	0.002
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.009	0.989	0.002
E06.1 Subacute thyroiditis	0.009	0.989	0.002
E06.0 Acute thyroiditis	0.009	0.989	0.002
I47 Paroxysmal tachycardia	0.011	0.989	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.989	0.011
M21 Other acquired deformities of limbs	0.000	0.989	0.011
M24 Other specific joint derangements	0.000	0.989	0.011
D74 Methaemoglobinaemia	0.000	0.989	0.011
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.989	0.011
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.989	0.011
I47.1 Supraventricular tachycardia	0.011	0.989	0.000
R47.0 Dysphasia and aphasia	0.000	0.989	0.011
S68 Traumatic amputation of wrist and hand	0.011	0.989	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.010	0.990	0.000
D12.5 Sigmoid colon	0.010	0.990	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.010	0.990	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.010	0.990	0.000
C18.1 Appendix	0.010	0.990	0.000
C71.9 Brain, unspecified	0.010	0.990	0.000
D75.0 Familial erythrocytosis	0.000	0.990	0.010
M31 Other necrotising vasculopathies	0.000	0.990	0.010
M24.0 Loose body in joint	0.000	0.990	0.010
M24.1 Other articular cartilage disorders	0.000	0.990	0.010
M32 Systemic lupus erythematosus	0.000	0.990	0.010
D12.4 Descending colon	0.010	0.990	0.000
D12.7 Rectosigmoid junction	0.010	0.990	0.000
C18.6 Descending colon	0.010	0.990	0.000
M21.1 Varus deformity, not elsewhere classified	0.000	0.990	0.010
S62 Fracture at wrist and hand level	0.010	0.990	0.000
C18.0 Caecum	0.010	0.990	0.000
C71.0 Cerebrum, except lobes and ventricles	0.010	0.990	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.010	0.990	0.000
M21.3 Wrist or foot drop (acquired)	0.000	0.991	0.009
M30 Polyarteritis nodosa and related conditions	0.000	0.991	0.009
D72.9 Disorder of white blood cells, unspecified	0.000	0.991	0.009
D72.0 Genetic anomalies of leukocytes	0.000	0.991	0.009
C18.2 Ascending colon	0.009	0.991	0.000
D73.9 Disease of spleen, unspecified	0.000	0.991	0.009
D73.8 Other diseases of spleen	0.000	0.991	0.009
D73.4 Cyst of spleen	0.000	0.991	0.009
D73.3 Abscess of spleen	0.000	0.991	0.009
D73.2 Chronic congestive splenomegaly	0.000	0.991	0.009
D73.1 Hypersplenism	0.000	0.991	0.009
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.991	0.009
C71 Malignant neoplasm of brain	0.009	0.991	0.000
M34 Systemic sclerosis	0.000	0.991	0.009
R03.1 Nonspecific low blood-pressure reading	0.000	0.991	0.009
S68.0 Traumatic amputation of thumb (complete)(partial)	0.009	0.991	0.000
S65 Injury of blood vessels at wrist and hand level	0.009	0.991	0.000
M24.02 Loose body in joint (Upper arm)	0.000	0.991	0.009
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.991	0.009
S66 Injury of muscle and tendon at wrist and hand level	0.009	0.991	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.991	0.009
C18.3 Hepatic flexure	0.009	0.991	0.000
C18.5 Splenic flexure	0.009	0.991	0.000
D41.4 Bladder	0.009	0.991	0.000
M24.01 Loose body in joint (Shoulder region)	0.000	0.991	0.009
M31.6 Other giant cell arteritis	0.000	0.991	0.009
S60.7 Multiple superficial injuries of wrist and hand	0.009	0.991	0.000
S60.1 Contusion of finger(s) with damage to nail	0.009	0.991	0.000
E66 Obesity	0.000	0.991	0.009
I47.0 Reentry ventricular arrhythmia	0.009	0.991	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.009	0.991	0.000
C18.8 Overlapping lesion of colon	0.008	0.991	0.000
C71.2 Temporal lobe	0.008	0.991	0.000
M21.0 Valgus deformity, not elsewhere classified	0.000	0.992	0.008
M33 Dermatopolymyositis	0.000	0.992	0.008
J98.4 Other disorders of lung	0.008	0.992	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.000	0.992	0.008
S63.3 Traumatic rupture of ligament of wrist and carpus	0.008	0.992	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.992	0.008
C77.2 Intra-abdominal lymph nodes	0.008	0.992	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.992	0.008
D76.3 Other histiocytosis syndromes	0.000	0.992	0.008
M21.4 Flat foot [pes planus] (acquired)	0.000	0.992	0.008
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.992	0.008
E66.0 Obesity due to excess calories	0.000	0.992	0.008
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.992	0.008
S62.7 Multiple fractures of fingers	0.008	0.992	0.000
S67 Crushing injury of wrist and hand	0.008	0.992	0.000
E06.3 Autoimmune thyroiditis	0.006	0.992	0.002
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.992	0.008
E05 Thyrotoxicosis [hyperthyroidism]	0.004	0.992	0.004
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.008	0.992	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.992	0.008
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.992	0.008
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.992	0.008
E06.9 Thyroiditis, unspecified	0.005	0.992	0.003
D73.5 Infarction of spleen	0.000	0.992	0.008
M21.9 Acquired deformity of limb, unspecified	0.000	0.992	0.008
M21.8 Other specified acquired deformities of limbs	0.000	0.992	0.008
M21.7 Unequal limb length (acquired)	0.000	0.992	0.008
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.992	0.008
M24.6 Ankylosis of joint	0.000	0.992	0.008
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.008	0.992	0.000
M24.9 Joint derangement, unspecified	0.000	0.992	0.008
D74.9 Methaemoglobinaemia, unspecified	0.000	0.992	0.008
D74.8 Other methaemoglobinaemias	0.000	0.992	0.008
D74.0 Congenital methaemoglobinaemia	0.000	0.992	0.008
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.008	0.992	0.000
M21.6 Other acquired deformities of ankle and foot	0.000	0.992	0.008
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.992	0.008
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.008	0.992	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.008	0.992	0.000
S68.4 Traumatic amputation of hand at wrist level	0.008	0.992	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.008	0.992	0.000
M24.2 Disorder of ligament	0.000	0.992	0.008
D72.1 Eosinophilia	0.000	0.992	0.008
M13.99 Arthritis, unspecified (Site unspecified)	0.000	0.992	0.008
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.992	0.007
S62.5 Fracture of thumb	0.008	0.992	0.000
E04 Other non-toxic goitre	0.007	0.993	0.001
M34.9 Systemic sclerosis, unspecified	0.000	0.993	0.007
M31.8 Other specified necrotising vasculopathies	0.000	0.993	0.007
M31.4 Aortic arch syndrome [Takayasu]	0.000	0.993	0.007
M31.2 Lethal midline granuloma	0.000	0.993	0.007
M31.1 Thrombotic microangiopathy	0.000	0.993	0.007
M31.0 Hypersensitivity angiitis	0.000	0.993	0.007
M24.09 Loose body in joint (Site unspecified)	0.000	0.993	0.007
M24.08 Loose body in joint (Other)	0.000	0.993	0.007
M24.06 Loose body in joint-Lower leg	0.000	0.993	0.007
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.993	0.007
M24.04 Loose body in joint (Hand)	0.000	0.993	0.007
M24.03 Loose body in joint (Forearm)	0.000	0.993	0.007
M24.00 Loose body in joint (Multiple sites)	0.000	0.993	0.007
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.993	0.007
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.993	0.007
M24.18 Other articular cartilage disorders (Other)	0.000	0.993	0.007
M24.14 Other articular cartilage disorders (Hand)	0.000	0.993	0.007
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.993	0.007
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.993	0.007
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.993	0.007
M32.8 Other forms of systemic lupus erythematosus	0.000	0.993	0.007
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.993	0.007
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.993	0.007
D86 Sarcoidosis	0.000	0.993	0.007
S64.3 Injury of digital nerve of thumb	0.007	0.993	0.000
S62.70 Multiple fractures of fingers (closed)	0.007	0.993	0.000
S60.2 Contusion of other parts of wrist and hand	0.007	0.993	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.007	0.993	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.993	0.007
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.993	0.007
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.993	0.007
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.993	0.007
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.993	0.007
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.993	0.007
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.993	0.007
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.993	0.007
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.993	0.007
S62.4 Multiple fractures of metacarpal bones	0.007	0.993	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.007	0.993	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.993	0.007
S60.0 Contusion of finger(s) without damage to nail	0.007	0.993	0.000
S62.1 Fracture of other carpal bone(s)	0.007	0.993	0.000
S63.5 Sprain and strain of wrist	0.007	0.993	0.000
S63.0 Dislocation of wrist	0.007	0.993	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.007	0.993	0.000
S63.1 Dislocation finger	0.007	0.993	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.007	0.993	0.000
S63.2 Multiple dislocations of fingers	0.007	0.993	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.993	0.007
S65.1 Injury of radial artery at wrist and hand level	0.007	0.993	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.993	0.007
M31.3 Wegener's granulomatosis	0.000	0.993	0.007
M24.7 Protrusio acetabuli	0.000	0.993	0.007
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.993	0.007
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.993	0.007
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.993	0.007
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.993	0.007
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.993	0.007
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.993	0.007
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.993	0.007
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.993	0.007
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.993	0.007
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.993	0.007
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.007	0.993	0.000
D12.9 Anus and anal canal	0.007	0.993	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.993	0.007
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.993	0.007
M30.2 Juvenile polyarteritis	0.000	0.993	0.007
C71.4 Occipital lobe	0.007	0.993	0.000
C71.3 Parietal lobe	0.007	0.993	0.000
M34.8 Other forms of systemic sclerosis	0.000	0.993	0.007
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.993	0.007
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.993	0.007
C71.7 Brain stem	0.007	0.993	0.000
C71.6 Cerebellum	0.007	0.993	0.000
C71.5 Cerebral ventricle	0.007	0.993	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.993	0.007
M34.0 Progressive systemic sclerosis	0.000	0.993	0.007
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.993	0.007
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.007	0.993	0.000
S65.5 Injury of blood vessel(s) of other finger	0.007	0.993	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.007	0.993	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.007	0.993	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.007	0.993	0.000
S65.4 Injury of blood vessel(s) of thumb	0.007	0.993	0.000
S65.3 Injury of deep palmar arch	0.007	0.993	0.000
S65.2 Injury of superficial palmar arch	0.007	0.993	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.007	0.993	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.993	0.007
S62.3 Fracture of other metacarpal bone	0.007	0.993	0.000
C18.4 Transverse colon	0.007	0.993	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.993	0.007
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.993	0.007
M36.3 Arthropathy in other blood disorders	0.000	0.993	0.007
M36.2 Haemophilic arthropathy	0.000	0.993	0.007
M36.1 Arthropathy in neoplastic disease	0.000	0.993	0.007
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.993	0.007
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.993	0.007
S69 Other and unspecified injuries of wrist and hand	0.006	0.993	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.993	0.007
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.007	0.993	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.007	0.993	0.000
S62.2 Fracture of first metacarpal bone	0.007	0.993	0.000
M31.9 Necrotising vasculopathy, unspecified	0.000	0.993	0.006
M33.2 Polymyositis	0.000	0.993	0.006
D86.0 Sarcoidosis of lung	0.000	0.993	0.007
M31.7 Microscopic polyangiitis	0.000	0.993	0.006
M24.23 Disorder of ligament (Forearm)	0.000	0.993	0.006
E66.1 Drug-induced obesity	0.000	0.993	0.006
M34.1 CR(E)ST syndrome	0.000	0.993	0.006
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.006	0.993	0.000
M35 Other systemic involvement of connective tissue	0.000	0.993	0.006
S62.50 Fracture of thumb (closed)	0.006	0.994	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.994	0.006
M24.07 Loose body in joint (Ankle and foot)	0.000	0.994	0.006
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.000	0.994	0.006
M21.2 Flexion deformity	0.000	0.994	0.006
M24.5 Contracture of joint	0.000	0.994	0.006
S62.0 Fracture of navicular [scaphoid] bone of hand	0.006	0.994	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.994	0.006
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.994	0.006
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.994	0.006
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.994	0.006
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.994	0.006
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.994	0.006
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.994	0.006
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.994	0.006
M33.9 Dermatopolymyositis, unspecified	0.000	0.994	0.006
M33.0 Juvenile dermatomyositis	0.000	0.994	0.006
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.006	0.994	0.000
S61.7 Multiple open wounds of wrist and hand	0.006	0.994	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.994	0.006
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.994	0.006
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.994	0.006
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.994	0.006
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.994	0.006
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.994	0.006
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.994	0.006
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.994	0.006
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.994	0.006
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.994	0.006
M30.0 Polyarteritis nodosa	0.000	0.994	0.006
M24.21 Disorder of ligament (Shoulder region)	0.000	0.994	0.006
M24.67 Ankylosis of joint (Ankle and foot)	0.000	0.994	0.006
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.000	0.994	0.006
I42.8 Other cardiomyopathies	0.006	0.994	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.000	0.994	0.006
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.000	0.994	0.006
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.000	0.994	0.006
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.000	0.994	0.006
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.000	0.994	0.006
E05.8 Other thyrotoxicosis	0.003	0.994	0.003
E05.5 Thyroid crisis or storm	0.003	0.994	0.003
E05.4 Thyrotoxicosis factitia	0.003	0.994	0.003
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.003	0.994	0.003
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.003	0.994	0.003
M21.79 Unequal limb length (acquired) (Site unspecified)	0.000	0.994	0.006
M21.78 Unequal limb length (acquired)-Other	0.000	0.994	0.006
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.000	0.994	0.006
M21.76 Unequal limb length (acquired) (Lower leg)	0.000	0.994	0.006
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.000	0.994	0.006
M21.74 Unequal limb length (acquired) (Hand)	0.000	0.994	0.006
M21.73 Unequal limb length (acquired) (Forearm)	0.000	0.994	0.006
M21.72 Unequal limb length (acquired) (Upper arm)	0.000	0.994	0.006
M21.71 Unequal limb length (acquired)-Shldr region	0.000	0.994	0.006
M21.70 Unequal limb length (acquired) (Multiple sites)	0.000	0.994	0.006

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations