TreeWAS – Variant ID: rs2524044

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
L40.5 Arthropathic psoriasis	0.000	0.000	1.000
L40 Psoriasis	0.000	0.000	1.000
L40.0 Psoriasis vulgaris	0.000	0.042	0.958
L40.4 Guttate psoriasis	0.000	0.283	0.717
L40.3 Pustulosis palmaris et plantaris	0.000	0.283	0.717
L40.2 Acrodermatitis continua	0.000	0.283	0.717
L40.1 Generalised pustular psoriasis	0.000	0.283	0.717
E03 Other hypothyroidism	0.610	0.388	0.001
L40.8 Other psoriasis	0.000	0.402	0.598
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.523	0.476	0.001
E03.5 Myxoedema coma	0.438	0.561	0.001
E03.4 Atrophy of thyroid (acquired)	0.438	0.561	0.001
E03.3 Postinfectious hypothyroidism	0.438	0.561	0.001
E03.1 Congenital hypothyroidism without goitre	0.438	0.561	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.438	0.561	0.001
L40-L45 Papulosquamous disorders	0.000	0.568	0.432
K90 Intestinal malabsorption	0.000	0.571	0.429
E03.8 Other specified hypothyroidism	0.398	0.601	0.001
K90.9 Intestinal malabsorption, unspecified	0.000	0.648	0.352
L43 Lichen planus	0.000	0.669	0.331
L44 Other papulosquamous disorders	0.000	0.690	0.310
L41 Parapsoriasis	0.000	0.690	0.310
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.690	0.310
K90.3 Pancreatic steatorrhoea	0.000	0.692	0.307
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.692	0.307
K90.1 Tropical sprue	0.000	0.692	0.307
L42 Pityriasis rosea	0.000	0.708	0.291
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.713	0.287
K90.8 Other intestinal malabsorption	0.000	0.739	0.261
L43.8 Other lichen planus	0.000	0.750	0.249
L43.9 Lichen planus, unspecified	0.000	0.751	0.249
L43.3 Subacute (active) lichen planus	0.000	0.762	0.238
L43.2 Lichenoid drug reaction	0.000	0.762	0.238
L43.1 Bullous lichen planus	0.000	0.762	0.238
L43.0 Hypertrophic lichen planus	0.000	0.762	0.238
L41.9 Parapsoriasis, unspecified	0.000	0.777	0.222
L41.8 Other parapsoriasis	0.000	0.777	0.222
L41.5 Retiform parapsoriasis	0.000	0.777	0.222
L41.4 Large plaque parapsoriasis	0.000	0.777	0.222
L41.3 Small plaque parapsoriasis	0.000	0.777	0.222
L41.2 Lymphomatoid papulosis	0.000	0.777	0.222
L41.1 Pityriasis lichenoides chronica	0.000	0.777	0.222
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.777	0.222
L44.9 Papulosquamous disorder, unspecified	0.000	0.777	0.222
L44.8 Other specified papulosquamous disorders	0.000	0.777	0.222
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.777	0.222
L44.3 Lichen ruber moniliformis	0.000	0.777	0.222
L44.2 Lichen striatus	0.000	0.777	0.222
L44.1 Lichen nitidus	0.000	0.777	0.222
L44.0 Pityriasis rubra pilaris	0.000	0.777	0.222
E00-E07 Disorders of thyroid gland	0.158	0.835	0.007
E07 Other disorders of thyroid	0.155	0.843	0.003
E07.9 Disorder of thyroid, unspecified	0.152	0.848	0.000
E07.8 Other specified disorders of thyroid	0.123	0.876	0.001
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.113	0.881	0.005
E00 Congenital iodine-deficiency syndrome	0.113	0.881	0.005
E02 Subclinical iodine-deficiency hypothyroidism	0.113	0.881	0.005
E07.1 Dyshormogenetic goitre	0.111	0.887	0.002
E07.0 Hypersecretion of calcitonin	0.111	0.887	0.002
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.081	0.915	0.004
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.081	0.915	0.004
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.081	0.915	0.004
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.081	0.915	0.004
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.081	0.915	0.004
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.081	0.915	0.004
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.081	0.915	0.004
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.081	0.915	0.004
E06 Thyroiditis	0.063	0.930	0.007
E06.5 Other chronic thyroiditis	0.045	0.950	0.005
E06.4 Drug-induced thyroiditis	0.045	0.950	0.005
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.045	0.950	0.005
E06.1 Subacute thyroiditis	0.045	0.950	0.005
E06.0 Acute thyroiditis	0.045	0.950	0.005
S64.4 Injury of digital nerve of other finger	0.047	0.953	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.010	0.959	0.031
E05.0 Thyrotoxicosis with diffuse goitre	0.001	0.964	0.035
R94.3 Abnormal results of cardiovascular function studies	0.036	0.964	0.000
E06.9 Thyroiditis, unspecified	0.028	0.966	0.006
E06.3 Autoimmune thyroiditis	0.029	0.967	0.005
E04 Other non-toxic goitre	0.029	0.968	0.003
E05.8 Other thyrotoxicosis	0.006	0.969	0.026
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.005	0.969	0.026
K90-K93 Other diseases of the digestive system	0.000	0.970	0.030
E05.5 Thyroid crisis or storm	0.008	0.970	0.022
E05.4 Thyrotoxicosis factitia	0.008	0.970	0.022
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.008	0.970	0.022
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.008	0.970	0.022
E05.9 Thyrotoxicosis, unspecified	0.000	0.973	0.027
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.973	0.027
C77.2 Intra-abdominal lymph nodes	0.026	0.974	0.000
M07.3 Other psoriatic arthropathies	0.000	0.974	0.026
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.975	0.025
E04.8 Other specified non-toxic goitre	0.021	0.977	0.002
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.977	0.023
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.978	0.022
E04.2 Non-toxic multinodular goitre	0.018	0.981	0.001
M07.38 Other psoriatic arthropathies (Other)	0.000	0.981	0.019
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.981	0.019
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.981	0.019
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.981	0.019
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.981	0.019
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.981	0.019
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.981	0.019
S64 Injury of nerves at wrist and hand level	0.018	0.982	0.000
E04.0 Non-toxic diffuse goitre	0.015	0.982	0.002
M25.5 Pain in joint	0.000	0.983	0.017
M25.54 Pain in joint (Hand)	0.000	0.983	0.017
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.983	0.017
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.984	0.016
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.984	0.016
K93.1 Megacolon in Chagas' disease	0.000	0.984	0.016
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.984	0.016
M25.51 Pain in joint (Shoulder region)	0.000	0.984	0.016
M25.59 Pain in joint (Site unspecified)	0.000	0.984	0.016
D75 Other diseases of blood and blood-forming organs	0.000	0.984	0.015
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.985	0.015
D70 Agranulocytosis	0.000	0.985	0.015
S64.2 Injury of radial nerve at wrist and hand level	0.015	0.985	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.015	0.985	0.000
E04.1 Non-toxic single thyroid nodule	0.013	0.985	0.001
E66.8 Other obesity	0.000	0.986	0.014
M25.77 Osteophyte (Ankle and foot)	0.000	0.986	0.014
D72 Other disorders of white blood cells	0.000	0.986	0.014
M25.58 Pain in joint (Other)	0.000	0.986	0.014
R94 Abnormal results of function studies	0.014	0.986	0.000
D72.8 Other specified disorders of white blood cells	0.000	0.986	0.014
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.986	0.014
D75.1 Secondary polycythaemia	0.000	0.987	0.013
I26 Pulmonary embolism	0.000	0.987	0.013
S64.9 Injury of unspecified nerve at wrist and hand level	0.013	0.987	0.000
S64.8 Injury of other nerves at wrist and hand level	0.013	0.987	0.000
M25.7 Osteophyte	0.000	0.987	0.013
D75.2 Essential thrombocytosis	0.000	0.987	0.013
R94.5 Abnormal results of liver function studies	0.013	0.987	0.000
G35 Multiple sclerosis	0.000	0.987	0.013
M25 Other joint disorders, not elsewhere classified	0.000	0.987	0.013
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.013	0.987	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.988	0.012
M25.71 Osteophyte (Shoulder region)	0.000	0.988	0.012
S64.1 Injury of median nerve at wrist and hand level	0.012	0.988	0.000
M25.56 Pain in joint (Lower leg)	0.000	0.988	0.012
I27.0 Primary pulmonary hypertension	0.000	0.988	0.012
M25.57 Pain in joint (Ankle and foot)	0.000	0.988	0.012
I27 Other pulmonary heart diseases	0.000	0.988	0.012
M25.9 Joint disorder, unspecified	0.000	0.988	0.012
S64.0 Injury of ulnar nerve at wrist and hand level	0.012	0.988	0.000
C77.4 Inguinal and lower limb lymph nodes	0.011	0.989	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.989	0.011
M25.74 Osteophyte (Hand)	0.000	0.989	0.011
C77.8 Lymph nodes of multiple regions	0.011	0.989	0.000
D74 Methaemoglobinaemia	0.000	0.989	0.011
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.989	0.011
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.989	0.011
M07 Psoriatic and enteropathic arthropathies	0.000	0.989	0.011
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.989	0.011
R94.7 Abnormal results of other endocrine function studies	0.011	0.989	0.000
M25.52 Pain in joint (Upper arm)	0.000	0.989	0.011
R94.0 Abnormal results of function studies of central nervous system	0.011	0.989	0.000
M25.72 Osteophyte (Upper arm)	0.000	0.989	0.011
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.989	0.011
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.989	0.011
M25.50 Pain in joint (Multiple sites)	0.000	0.989	0.011
I27.9 Pulmonary heart disease, unspecified	0.000	0.989	0.011
D73 Diseases of spleen	0.000	0.989	0.011
E66 Obesity	0.000	0.989	0.011
D72.9 Disorder of white blood cells, unspecified	0.000	0.990	0.010
D72.0 Genetic anomalies of leukocytes	0.000	0.990	0.010
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.990	0.010
D75.0 Familial erythrocytosis	0.000	0.990	0.010
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.010	0.990	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.990	0.010
R94.8 Abnormal results of function studies of other organs and systems	0.010	0.990	0.000
C77.1 Intrathoracic lymph nodes	0.010	0.990	0.000
R94.2 Abnormal results of pulmonary function studies	0.010	0.990	0.000
M25.76 Osteophyte (Lower leg)	0.000	0.990	0.010
E66.0 Obesity due to excess calories	0.000	0.990	0.010
M25.73 Osteophyte (Forearm)	0.000	0.990	0.010
M25.70 Osteophyte (Multiple sites)	0.000	0.990	0.010
D72.1 Eosinophilia	0.000	0.990	0.010
D86.9 Sarcoidosis, unspecified	0.000	0.990	0.010
M25.79 Osteophyte (Site unspecified)	0.000	0.991	0.009
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.991	0.009
M25.2 Flail joint	0.000	0.991	0.009
M25.1 Fistula of joint	0.000	0.991	0.009
I28 Other diseases of pulmonary vessels	0.000	0.991	0.009
D86 Sarcoidosis	0.000	0.991	0.009
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.991	0.009
G37 Other demyelinating diseases of central nervous system	0.000	0.991	0.009
E04.9 Non-toxic goitre, unspecified	0.007	0.991	0.002
C77.9 Lymph node, unspecified	0.009	0.991	0.000
M25.53 Pain in joint (Forearm)	0.000	0.991	0.009
D73.8 Other diseases of spleen	0.000	0.991	0.009
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.991	0.009
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.991	0.009
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.991	0.009
I27.1 Kyphoscoliotic heart disease	0.000	0.991	0.009
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.991	0.008
M25.98 Joint disorder, unspecified (Other)	0.000	0.991	0.008
M25.94 Joint disorder, unspecified (Hand)	0.000	0.991	0.008
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.991	0.008
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.991	0.008
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.991	0.008
C77.5 Intrapelvic lymph nodes	0.009	0.991	0.000
R94.6 Abnormal results of thyroid function studies	0.008	0.991	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.991	0.008
D74.9 Methaemoglobinaemia, unspecified	0.000	0.992	0.008
D74.8 Other methaemoglobinaemias	0.000	0.992	0.008
D74.0 Congenital methaemoglobinaemia	0.000	0.992	0.008
I27.2 Other secondary pulmonary hypertension	0.000	0.992	0.008
M07.6 Other enteropathic arthropathies	0.000	0.992	0.008
M07.5 Arthropathy in ulcerative colitis	0.000	0.992	0.008
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.992	0.008
M07.2 Psoriatic spondylitis	0.000	0.992	0.008
M07.1 Arthritis mutilans	0.000	0.992	0.008
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.992	0.008
M25.0 Haemarthrosis	0.000	0.992	0.008
C90.0 Multiple myeloma	0.000	0.992	0.008
D86.0 Sarcoidosis of lung	0.000	0.992	0.008
D73.1 Hypersplenism	0.000	0.992	0.008
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.992	0.008
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.992	0.008
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.992	0.008
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.992	0.008
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.992	0.008
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.992	0.008
D73.9 Disease of spleen, unspecified	0.000	0.992	0.008
D73.3 Abscess of spleen	0.000	0.992	0.008
D73.2 Chronic congestive splenomegaly	0.000	0.992	0.008
D86.8 Sarcoidosis of other and combined sites	0.000	0.992	0.008
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.992	0.008
E66.1 Drug-induced obesity	0.000	0.992	0.008
I28.8 Other specified diseases of pulmonary vessels	0.000	0.992	0.008
E65-E68 Obesity and other hyperalimentation	0.000	0.992	0.008
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.992	0.008
D76.3 Other histiocytosis syndromes	0.000	0.992	0.007
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.992	0.008
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.993	0.007
D73.0 Hyposplenism	0.000	0.993	0.007
D86.1 Sarcoidosis of lymph nodes	0.000	0.993	0.007
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.993	0.007
D73.4 Cyst of spleen	0.000	0.993	0.007
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.993	0.007
S64.3 Injury of digital nerve of thumb	0.007	0.993	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.993	0.007
D86.3 Sarcoidosis of skin	0.000	0.993	0.007
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.993	0.007
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.993	0.007
M25.19 Fistula of joint (Site unspecified)	0.000	0.993	0.007
M25.18 Fistula of joint (Other)	0.000	0.993	0.007
M25.17 Fistula of joint (Ankle and foot)	0.000	0.993	0.007
M25.16 Fistula of joint (Lower leg)	0.000	0.993	0.007
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.993	0.007
M25.14 Fistula of joint (Hand)	0.000	0.993	0.007
M25.13 Fistula of joint (Forearm)	0.000	0.993	0.007
M25.12 Fistula of joint (Upper arm)	0.000	0.993	0.007
M25.11 Fistula of joint (Shoulder region)	0.000	0.993	0.007
M25.10 Fistula of joint (Multiple sites)	0.000	0.993	0.007
M25.29 Flail joint (Site unspecified)	0.000	0.993	0.007
M25.28 Flail joint (Other)	0.000	0.993	0.007
M25.27 Flail joint (Ankle and foot)	0.000	0.993	0.007
M25.26 Flail joint (Lower leg)	0.000	0.993	0.007
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.993	0.007
M25.24 Flail joint (Hand)	0.000	0.993	0.007
M25.23 Flail joint (Forearm)	0.000	0.993	0.007
M25.22 Flail joint (Upper arm)	0.000	0.993	0.007
M25.21 Flail joint (Shoulder region)	0.000	0.993	0.007
M25.20 Flail joint (Multiple sites)	0.000	0.993	0.007
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.993	0.007
I28.1 Aneurysm of pulmonary artery	0.000	0.993	0.007
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.993	0.007
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.993	0.007
D80-D89 Certain disorders involving the immune mechanism	0.000	0.993	0.007
G37.5 Concentric sclerosis [Balo]	0.000	0.993	0.007
G37.4 Subacute necrotising myelitis	0.000	0.993	0.007
G37.2 Central pontine myelinolysis	0.000	0.993	0.007
G37.1 Central demyelination of corpus callosum	0.000	0.993	0.007
G37.0 Diffuse sclerosis	0.000	0.993	0.007
R03.1 Nonspecific low blood-pressure reading	0.000	0.993	0.007
D73.5 Infarction of spleen	0.000	0.993	0.007
G36 Other acute disseminated demyelination	0.000	0.993	0.007
I10 Essential (primary) hypertension	0.007	0.993	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.993	0.006
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.993	0.007
C90.2 Plasmacytoma, extramedullary	0.000	0.993	0.007
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.994	0.006
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.994	0.006
E65 Localised adiposity	0.000	0.994	0.006
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.000	0.994	0.006
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.000	0.994	0.006
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.000	0.994	0.006
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.000	0.994	0.006
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.000	0.994	0.006
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.000	0.994	0.006
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.000	0.994	0.006
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.000	0.994	0.006
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.000	0.994	0.006
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.000	0.994	0.006
M07.19 Arthritis mutilans (Site unspecified)	0.000	0.994	0.006
M07.18 Arthritis mutilans (Other)	0.000	0.994	0.006
M07.17 Arthritis mutilans (Ankle and foot)	0.000	0.994	0.006
M07.16 Arthritis mutilans (Lower leg)	0.000	0.994	0.006
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.000	0.994	0.006
M07.14 Arthritis mutilans (Hand)	0.000	0.994	0.006
M07.13 Arthritis mutilans (Forearm)	0.000	0.994	0.006
M07.12 Arthritis mutilans (Upper arm)	0.000	0.994	0.006
M07.11 Arthritis mutilans (Shoulder region)	0.000	0.994	0.006
M07.10 Arthritis mutilans (Multiple sites)	0.000	0.994	0.006
M07.29 Psoriatic spondylitis (Site unspecified)	0.000	0.994	0.006
M07.28 Psoriatic spondylitis (Other)	0.000	0.994	0.006
M07.27 Psoriatic spondylitis (Ankle and foot)	0.000	0.994	0.006
M07.26 Psoriatic spondylitis (Lower leg)	0.000	0.994	0.006
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.000	0.994	0.006
M07.24 Psoriatic spondylitis (Hand)	0.000	0.994	0.006
M07.23 Psoriatic spondylitis (Forearm)	0.000	0.994	0.006
M07.22 Psoriatic spondylitis (Upper arm)	0.000	0.994	0.006
M07.21 Psoriatic spondylitis (Shoulder region)	0.000	0.994	0.006
M07.20 Psoriatic spondylitis (Multiple sites)	0.000	0.994	0.006
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.000	0.994	0.006
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.000	0.994	0.006
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.000	0.994	0.006
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.000	0.994	0.006
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.000	0.994	0.006
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.000	0.994	0.006
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.000	0.994	0.006
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.000	0.994	0.006
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.000	0.994	0.006
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.000	0.994	0.006
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.000	0.994	0.006
M07.58 Arthropathy in ulcerative colitis (Other)	0.000	0.994	0.006
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.000	0.994	0.006
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.000	0.994	0.006
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.000	0.994	0.006
M07.54 Arthropathy in ulcerative colitis (Hand)	0.000	0.994	0.006
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.000	0.994	0.006
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.000	0.994	0.006
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.000	0.994	0.006
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.000	0.994	0.006
M07.69 Other enteropathic arthropathies (Site unspecified)	0.000	0.994	0.006
M07.68 Other enteropathic arthropathies (Other)	0.000	0.994	0.006
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.000	0.994	0.006
M07.66 Other enteropathic arthropathies (Lower leg)	0.000	0.994	0.006
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.000	0.994	0.006
M07.64 Other enteropathic arthropathies (Hand)	0.000	0.994	0.006
M07.63 Other enteropathic arthropathies (Forearm)	0.000	0.994	0.006
M07.62 Other enteropathic arthropathies (Upper arm)	0.000	0.994	0.006
M07.61 Other enteropathic arthropathies (Shoulder region)	0.000	0.994	0.006
M07.60 Other enteropathic arthropathies (Multiple sites)	0.000	0.994	0.006
M25.09 Haemarthrosis (Site unspecified)	0.000	0.994	0.006
M25.08 Haemarthrosis (Other)	0.000	0.994	0.006
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.994	0.006
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.994	0.006
M25.04 Haemarthrosis (Hand)	0.000	0.994	0.006
M25.03 Haemarthrosis (Forearm)	0.000	0.994	0.006
M25.02 Haemarthrosis (Upper arm)	0.000	0.994	0.006
M25.01 Haemarthrosis (Shoulder region)	0.000	0.994	0.006
M25.00 Haemarthrosis (Multiple sites)	0.000	0.994	0.006
M25.8 Other specified joint disorders	0.000	0.994	0.006
D51 Vitamin B12 deficiency anaemia	0.000	0.994	0.006
E10.3 With ophthalmic complications	0.000	0.994	0.006
M25.4 Effusion of joint	0.000	0.994	0.006
M25.84 Other specified joint disorders (Hand)	0.000	0.994	0.006
S60-S69 Injuries to the wrist and hand	0.006	0.994	0.000
M25.46 Effusion of joint (Lower leg)	0.000	0.994	0.006
E67 Other hyperalimentation	0.000	0.994	0.006
E68 Sequelae of hyperalimentation	0.000	0.994	0.006
M25.3 Other instability of joint	0.000	0.994	0.006
C18.1 Appendix	0.006	0.994	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.006	0.994	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.006	0.994	0.000
D50-D53 Nutritional anaemias	0.000	0.994	0.005
N05.9 Unspecified	0.005	0.995	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.995	0.005
H40.2 Primary angle-closure glaucoma	0.005	0.995	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.005	0.995	0.000
C18.7 Sigmoid colon	0.005	0.995	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.995	0.005
D82 Immunodeficiency associated with other major defects	0.000	0.995	0.005
D81 Combined immunodeficiencies	0.000	0.995	0.005
M25.06 Haemarthrosis (Lower leg)	0.000	0.995	0.005
E10.2 With renal complications	0.000	0.995	0.005
C18 Malignant neoplasm of colon	0.005	0.995	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.995	0.005
G36.9 Acute disseminated demyelination, unspecified	0.000	0.995	0.005
G36.8 Other specified acute disseminated demyelination	0.000	0.995	0.005
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.995	0.005
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.995	0.005
E10 Insulin-dependent diabetes mellitus	0.000	0.995	0.005
R94.4 Abnormal results of kidney function studies	0.005	0.995	0.001
D83 Common variable immunodeficiency	0.000	0.995	0.005
C78.7 Secondary malignant neoplasm of liver	0.005	0.995	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.005	0.995	0.000
S68 Traumatic amputation of wrist and hand	0.005	0.995	0.000
C90.1 Plasma cell leukaemia	0.000	0.995	0.005
D55-D59 Haemolytic anaemias	0.000	0.995	0.005
C18.2 Ascending colon	0.005	0.995	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.005	0.995	0.000
G36.0 Neuromyelitis optica [Devic]	0.000	0.995	0.005
E10.1 With ketoacidosis	0.000	0.995	0.005
D53 Other nutritional anaemias	0.000	0.995	0.005
S60 Superficial injury of wrist and hand	0.005	0.995	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.995	0.005
M25.82 Other specified joint disorders (Upper arm)	0.000	0.995	0.005
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.995	0.005
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.995	0.005
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.995	0.005
D51.2 Transcobalamin II deficiency	0.000	0.995	0.005
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.995	0.005
D84 Other immunodeficiencies	0.000	0.995	0.004
M25.49 Effusion of joint (Site unspecified)	0.000	0.995	0.004
M25.48 Effusion of joint (Other)	0.000	0.995	0.004
M25.43 Effusion of joint (Forearm)	0.000	0.995	0.004
M25.41 Effusion of joint (Shoulder region)	0.000	0.995	0.004
C18.5 Splenic flexure	0.005	0.995	0.000
C90.3 Solitary plasmacytoma	0.000	0.995	0.004
C18.6 Descending colon	0.005	0.995	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.004	0.995	0.000
C77.0 Lymph nodes of head, face and neck	0.004	0.995	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.004	0.995	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.996	0.004
M25.83 Other specified joint disorders (Forearm)	0.000	0.996	0.004
E67.8 Other specified hyperalimentation	0.000	0.996	0.004
E67.3 Hypervitaminosis D	0.000	0.996	0.004
E67.2 Megavitamin-B6 syndrome	0.000	0.996	0.004
E67.1 Hypercarotenaemia	0.000	0.996	0.004
E67.0 Hypervitaminosis A	0.000	0.996	0.004
M25.39 Other instability of joint (Site unspecified)	0.000	0.996	0.004
M25.38 Other instability of joint (Other)	0.000	0.996	0.004
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.996	0.004
M25.32 Other instability of joint (Upper arm)	0.000	0.996	0.004
M25.30 Other instability of joint (Multiple sites)	0.000	0.996	0.004
S65 Injury of blood vessels at wrist and hand level	0.004	0.996	0.000
M25.37 Other instability of joint (Ankle and foot)	0.000	0.996	0.004
D41.4 Bladder	0.004	0.996	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.004	0.996	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	0.996	0.004
M25.36 Other instability of joint (Lower leg)	0.000	0.996	0.004
D53.9 Nutritional anaemia, unspecified	0.000	0.996	0.004
S60.8 Other superficial injuries of wrist and hand	0.004	0.996	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.996	0.004
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.004	0.996	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.996	0.004
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.996	0.004
S60.9 Superficial injury of wrist and hand, unspecified	0.004	0.996	0.000
E10.5 With peripheral circulatory complications	0.000	0.996	0.004
E10-E14 Diabetes mellitus	0.000	0.996	0.004
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.004	0.996	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.996	0.004
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.004	0.996	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.004	0.996	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.996	0.004
M46.9 Inflammatory spondylopathy, unspecified	0.004	0.996	0.000
C18.3 Hepatic flexure	0.004	0.996	0.000
E10.8 With unspecified complications	0.000	0.996	0.004
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.996	0.004
K91.1 Postgastric surgery syndromes	0.000	0.996	0.004
D58 Other hereditary haemolytic anaemias	0.000	0.996	0.004
M25.88 Other specified joint disorders (Other)	0.000	0.996	0.004
D81.9 Combined immunodeficiency, unspecified	0.000	0.996	0.004
D81.8 Other combined immunodeficiencies	0.000	0.996	0.004
D81.7 Major histocompatibility complex class II deficiency	0.000	0.996	0.004
D81.6 Major histocompatibility complex class I deficiency	0.000	0.996	0.004
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.996	0.004
D81.4 Nezelof's syndrome	0.000	0.996	0.004
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.996	0.004
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.996	0.004
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.996	0.004
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.996	0.004
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.996	0.004
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.996	0.004
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.996	0.004
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.996	0.004
D82.2 Immunodeficiency with short-limbed stature	0.000	0.996	0.004
D82.1 Di George's syndrome	0.000	0.996	0.004
D82.0 Wiskott-Aldrich syndrome	0.000	0.996	0.004
E10.6 With other specified complications	0.000	0.996	0.004
M81.4 Drug-induced osteoporosis	0.004	0.996	0.000
M25.33 Other instability of joint (Forearm)	0.000	0.996	0.004
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.996	0.004
M25.42 Effusion of joint (Upper arm)	0.000	0.996	0.004
K91.5 Postcholecystectomy syndrome	0.000	0.996	0.004
D89.1 Cryoglobulinaemia	0.000	0.996	0.004
L10-L14 Bullous disorders	0.000	0.996	0.004
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.996	0.004
D89.3 Immune reconstitution syndrome	0.000	0.996	0.004
E10.7 With multiple complications	0.000	0.996	0.004
D83.8 Other common variable immunodeficiencies	0.000	0.996	0.004
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.996	0.004
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.996	0.004
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.996	0.004
S63.3 Traumatic rupture of ligament of wrist and carpus	0.004	0.996	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.004	0.996	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.996	0.004
S67 Crushing injury of wrist and hand	0.004	0.996	0.000
M25.44 Effusion of joint (Hand)	0.000	0.996	0.004
M25.40 Effusion of joint (Multiple sites)	0.000	0.996	0.004
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.004	0.996	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations