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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2524049
log Bayes Factor = 30.3111
Chromosome 6   position 31,255,953  (GRCh37) Explore rs2524049 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
L40.0 Psoriasis vulgaris
0.000 0.040 0.960
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.3 Pustulosis palmaris et plantaris
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E03 Other hypothyroidism
0.654 0.345 0.001
L40.8 Other psoriasis
0.000 0.399 0.600
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.579 0.421 0.001
E03.5 Myxoedema coma
0.469 0.530 0.001
E03.4 Atrophy of thyroid (acquired)
0.469 0.530 0.001
E03.3 Postinfectious hypothyroidism
0.469 0.530 0.001
E03.1 Congenital hypothyroidism without goitre
0.469 0.530 0.001
E03.0 Congenital hypothyroidism with diffuse goitre
0.469 0.530 0.001
L40-L45 Papulosquamous disorders
0.000 0.539 0.461
K90 Intestinal malabsorption
0.000 0.555 0.445
E03.8 Other specified hypothyroidism
0.423 0.577 0.001
K90.9 Intestinal malabsorption, unspecified
0.000 0.632 0.368
L43 Lichen planus
0.000 0.635 0.365
L44 Other papulosquamous disorders
0.000 0.669 0.331
L41 Parapsoriasis
0.000 0.669 0.331
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.669 0.331
K90.3 Pancreatic steatorrhoea
0.000 0.681 0.319
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.681 0.319
K90.1 Tropical sprue
0.000 0.681 0.319
L42 Pityriasis rosea
0.000 0.688 0.312
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.700 0.300
L43.9 Lichen planus, unspecified
0.000 0.715 0.285
L43.8 Other lichen planus
0.000 0.724 0.276
K90.8 Other intestinal malabsorption
0.000 0.729 0.271
L43.3 Subacute (active) lichen planus
0.000 0.738 0.262
L43.2 Lichenoid drug reaction
0.000 0.738 0.262
L43.1 Bullous lichen planus
0.000 0.738 0.262
L43.0 Hypertrophic lichen planus
0.000 0.738 0.262
L41.9 Parapsoriasis, unspecified
0.000 0.762 0.237
L41.8 Other parapsoriasis
0.000 0.762 0.237
L41.5 Retiform parapsoriasis
0.000 0.762 0.237
L41.4 Large plaque parapsoriasis
0.000 0.762 0.237
L41.3 Small plaque parapsoriasis
0.000 0.762 0.237
L41.2 Lymphomatoid papulosis
0.000 0.762 0.237
L41.1 Pityriasis lichenoides chronica
0.000 0.762 0.237
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.762 0.237
L44.9 Papulosquamous disorder, unspecified
0.000 0.762 0.237
L44.8 Other specified papulosquamous disorders
0.000 0.762 0.237
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.762 0.237
L44.3 Lichen ruber moniliformis
0.000 0.762 0.237
L44.2 Lichen striatus
0.000 0.762 0.237
L44.1 Lichen nitidus
0.000 0.762 0.237
L44.0 Pityriasis rubra pilaris
0.000 0.762 0.237
E00-E07 Disorders of thyroid gland
0.162 0.831 0.007
E07 Other disorders of thyroid
0.159 0.839 0.002
E07.9 Disorder of thyroid, unspecified
0.156 0.844 0.000
E07.8 Other specified disorders of thyroid
0.124 0.875 0.001
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.116 0.879 0.005
E00 Congenital iodine-deficiency syndrome
0.116 0.879 0.005
E02 Subclinical iodine-deficiency hypothyroidism
0.116 0.879 0.005
E07.1 Dyshormogenetic goitre
0.114 0.884 0.002
E07.0 Hypersecretion of calcitonin
0.114 0.884 0.002
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.083 0.913 0.004
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.083 0.913 0.004
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.083 0.913 0.004
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.083 0.913 0.004
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.083 0.913 0.004
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.083 0.913 0.004
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.083 0.913 0.004
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.083 0.913 0.004
E06 Thyroiditis
0.064 0.930 0.006
E06.5 Other chronic thyroiditis
0.046 0.950 0.005
E06.4 Drug-induced thyroiditis
0.046 0.950 0.005
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.046 0.950 0.005
E06.1 Subacute thyroiditis
0.046 0.950 0.005
E06.0 Acute thyroiditis
0.046 0.950 0.005
R94.3 Abnormal results of cardiovascular function studies
0.044 0.956 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.010 0.956 0.034
S64.4 Injury of digital nerve of other finger
0.040 0.960 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.001 0.961 0.039
E06.9 Thyroiditis, unspecified
0.028 0.966 0.006
E05.8 Other thyrotoxicosis
0.006 0.966 0.028
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.005 0.967 0.028
E06.3 Autoimmune thyroiditis
0.028 0.967 0.005
E05.5 Thyroid crisis or storm
0.008 0.968 0.024
E05.4 Thyrotoxicosis factitia
0.008 0.968 0.024
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.008 0.968 0.024
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.008 0.968 0.024
K90-K93 Other diseases of the digestive system
0.000 0.968 0.032
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.969 0.031
M07.3 Other psoriatic arthropathies
0.000 0.970 0.030
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.971 0.029
E05.9 Thyrotoxicosis, unspecified
0.000 0.971 0.029
E04 Other non-toxic goitre
0.025 0.972 0.003
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.974 0.026
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.977 0.023
M07.38 Other psoriatic arthropathies (Other)
0.000 0.978 0.021
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.978 0.021
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.978 0.021
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.978 0.021
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.978 0.021
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.978 0.021
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.978 0.021
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.979 0.021
E04.8 Other specified non-toxic goitre
0.018 0.980 0.002
D70 Agranulocytosis
0.000 0.981 0.019
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.982 0.018
D75 Other diseases of blood and blood-forming organs
0.000 0.982 0.018
I26 Pulmonary embolism
0.000 0.983 0.017
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.983 0.017
K93.1 Megacolon in Chagas' disease
0.000 0.983 0.017
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.983 0.017
D72 Other disorders of white blood cells
0.000 0.983 0.017
D75.8 Other specified diseases of blood and blood-forming organs
0.000 0.984 0.016
G35 Multiple sclerosis
0.000 0.984 0.016
D72.8 Other specified disorders of white blood cells
0.000 0.984 0.016
R94 Abnormal results of function studies
0.016 0.984 0.000
E04.0 Non-toxic diffuse goitre
0.013 0.984 0.002
S64 Injury of nerves at wrist and hand level
0.016 0.984 0.000
D75.1 Secondary polycythaemia
0.000 0.984 0.016
I27.0 Primary pulmonary hypertension
0.000 0.984 0.016
E04.2 Non-toxic multinodular goitre
0.015 0.985 0.001
I27 Other pulmonary heart diseases
0.000 0.985 0.015
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.985 0.015
R94.5 Abnormal results of liver function studies
0.015 0.985 0.000
D75.2 Essential thrombocytosis
0.000 0.985 0.014
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.986 0.014
I27.9 Pulmonary heart disease, unspecified
0.000 0.986 0.014
C77.2 Intra-abdominal lymph nodes
0.014 0.986 0.000
D74 Methaemoglobinaemia
0.000 0.987 0.013
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.987 0.013
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.987 0.013
M07 Psoriatic and enteropathic arthropathies
0.000 0.987 0.013
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.987 0.013
S64.7 Injury of multiple nerves at wrist and hand level
0.013 0.987 0.000
D73 Diseases of spleen
0.000 0.987 0.013
R94.7 Abnormal results of other endocrine function studies
0.012 0.987 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.012 0.987 0.000
R94.0 Abnormal results of function studies of central nervous system
0.012 0.988 0.000
E04.1 Non-toxic single thyroid nodule
0.011 0.988 0.001
D72.9 Disorder of white blood cells, unspecified
0.000 0.988 0.012
D72.0 Genetic anomalies of leukocytes
0.000 0.988 0.012
D75.0 Familial erythrocytosis
0.000 0.988 0.012
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.988 0.012
G37 Other demyelinating diseases of central nervous system
0.000 0.988 0.012
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.012 0.988 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.988 0.012
I10 Essential (primary) hypertension
0.012 0.988 0.000
I28 Other diseases of pulmonary vessels
0.000 0.988 0.012
R94.8 Abnormal results of function studies of other organs and systems
0.011 0.988 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.988 0.011
D72.1 Eosinophilia
0.000 0.988 0.011
S64.9 Injury of unspecified nerve at wrist and hand level
0.011 0.988 0.000
S64.8 Injury of other nerves at wrist and hand level
0.011 0.988 0.000
E66.8 Other obesity
0.000 0.989 0.011
I27.1 Kyphoscoliotic heart disease
0.000 0.989 0.011
R94.2 Abnormal results of pulmonary function studies
0.011 0.989 0.000
I27.2 Other secondary pulmonary hypertension
0.000 0.989 0.011
S64.0 Injury of ulnar nerve at wrist and hand level
0.011 0.989 0.000
S64.1 Injury of median nerve at wrist and hand level
0.010 0.990 0.000
D73.8 Other diseases of spleen
0.000 0.990 0.010
D86.9 Sarcoidosis, unspecified
0.000 0.990 0.010
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.990 0.010
D74.9 Methaemoglobinaemia, unspecified
0.000 0.990 0.010
D74.8 Other methaemoglobinaemias
0.000 0.990 0.010
D74.0 Congenital methaemoglobinaemia
0.000 0.990 0.010
R94.6 Abnormal results of thyroid function studies
0.010 0.990 0.000
D73.1 Hypersplenism
0.000 0.990 0.009
D86 Sarcoidosis
0.000 0.990 0.010
I28.8 Other specified diseases of pulmonary vessels
0.000 0.990 0.009
M07.6 Other enteropathic arthropathies
0.000 0.990 0.009
M07.5 Arthropathy in ulcerative colitis
0.000 0.990 0.009
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.990 0.009
M07.2 Psoriatic spondylitis
0.000 0.990 0.009
M07.1 Arthritis mutilans
0.000 0.990 0.009
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.990 0.009
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.990 0.009
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.990 0.009
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.990 0.009
D73.9 Disease of spleen, unspecified
0.000 0.991 0.009
D73.3 Abscess of spleen
0.000 0.991 0.009
D73.2 Chronic congestive splenomegaly
0.000 0.991 0.009
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.991 0.009
D73.0 Hyposplenism
0.000 0.991 0.009
I27.8 Other specified pulmonary heart diseases
0.000 0.991 0.009
D76.3 Other histiocytosis syndromes
0.000 0.991 0.009
G37.5 Concentric sclerosis [Balo]
0.000 0.991 0.009
G37.4 Subacute necrotising myelitis
0.000 0.991 0.009
G37.2 Central pontine myelinolysis
0.000 0.991 0.009
G37.1 Central demyelination of corpus callosum
0.000 0.991 0.009
G37.0 Diffuse sclerosis
0.000 0.991 0.009
D73.4 Cyst of spleen
0.000 0.991 0.009
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.991 0.008
I28.1 Aneurysm of pulmonary artery
0.000 0.991 0.008
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.991 0.008
G36 Other acute disseminated demyelination
0.000 0.991 0.009
E66 Obesity
0.000 0.992 0.008
D86.8 Sarcoidosis of other and combined sites
0.000 0.992 0.008
D86.0 Sarcoidosis of lung
0.000 0.992 0.008
C90.0 Multiple myeloma
0.000 0.992 0.008
D73.5 Infarction of spleen
0.000 0.992 0.008
M25.54 Pain in joint (Hand)
0.000 0.992 0.008
E04.9 Non-toxic goitre, unspecified
0.006 0.992 0.002
E66.0 Obesity due to excess calories
0.000 0.992 0.008
D86.1 Sarcoidosis of lymph nodes
0.000 0.992 0.008
M25.5 Pain in joint
0.000 0.993 0.007
D80-D89 Certain disorders involving the immune mechanism
0.000 0.993 0.007
D86.3 Sarcoidosis of skin
0.000 0.993 0.007
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.993 0.007
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.993 0.007
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.000 0.993 0.007
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.000 0.993 0.007
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.000 0.993 0.007
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.000 0.993 0.007
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.000 0.993 0.007
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.000 0.993 0.007
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.000 0.993 0.007
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.000 0.993 0.007
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.000 0.993 0.007
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.000 0.993 0.007
M07.19 Arthritis mutilans (Site unspecified)
0.000 0.993 0.007
M07.18 Arthritis mutilans (Other)
0.000 0.993 0.007
M07.17 Arthritis mutilans (Ankle and foot)
0.000 0.993 0.007
M07.16 Arthritis mutilans (Lower leg)
0.000 0.993 0.007
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.000 0.993 0.007
M07.14 Arthritis mutilans (Hand)
0.000 0.993 0.007
M07.13 Arthritis mutilans (Forearm)
0.000 0.993 0.007
M07.12 Arthritis mutilans (Upper arm)
0.000 0.993 0.007
M07.11 Arthritis mutilans (Shoulder region)
0.000 0.993 0.007
M07.10 Arthritis mutilans (Multiple sites)
0.000 0.993 0.007
M07.29 Psoriatic spondylitis (Site unspecified)
0.000 0.993 0.007
M07.28 Psoriatic spondylitis (Other)
0.000 0.993 0.007
M07.27 Psoriatic spondylitis (Ankle and foot)
0.000 0.993 0.007
M07.26 Psoriatic spondylitis (Lower leg)
0.000 0.993 0.007
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.000 0.993 0.007
M07.24 Psoriatic spondylitis (Hand)
0.000 0.993 0.007
M07.23 Psoriatic spondylitis (Forearm)
0.000 0.993 0.007
M07.22 Psoriatic spondylitis (Upper arm)
0.000 0.993 0.007
M07.21 Psoriatic spondylitis (Shoulder region)
0.000 0.993 0.007
M07.20 Psoriatic spondylitis (Multiple sites)
0.000 0.993 0.007
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.000 0.993 0.007
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.000 0.993 0.007
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.000 0.993 0.007
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.000 0.993 0.007
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.000 0.993 0.007
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.000 0.993 0.007
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.000 0.993 0.007
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.000 0.993 0.007
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.000 0.993 0.007
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.000 0.993 0.007
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.000 0.993 0.007
M07.58 Arthropathy in ulcerative colitis (Other)
0.000 0.993 0.007
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.000 0.993 0.007
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.000 0.993 0.007
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.000 0.993 0.007
M07.54 Arthropathy in ulcerative colitis (Hand)
0.000 0.993 0.007
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.000 0.993 0.007
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.000 0.993 0.007
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.000 0.993 0.007
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.000 0.993 0.007
M07.69 Other enteropathic arthropathies (Site unspecified)
0.000 0.993 0.007
M07.68 Other enteropathic arthropathies (Other)
0.000 0.993 0.007
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.000 0.993 0.007
M07.66 Other enteropathic arthropathies (Lower leg)
0.000 0.993 0.007
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.000 0.993 0.007
M07.64 Other enteropathic arthropathies (Hand)
0.000 0.993 0.007
M07.63 Other enteropathic arthropathies (Forearm)
0.000 0.993 0.007
M07.62 Other enteropathic arthropathies (Upper arm)
0.000 0.993 0.007
M07.61 Other enteropathic arthropathies (Shoulder region)
0.000 0.993 0.007
M07.60 Other enteropathic arthropathies (Multiple sites)
0.000 0.993 0.007
M25.51 Pain in joint (Shoulder region)
0.000 0.993 0.007
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.007 0.993 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.993 0.007
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.993 0.007
R03.1 Nonspecific low blood-pressure reading
0.000 0.993 0.007
M25.59 Pain in joint (Site unspecified)
0.000 0.993 0.007
C77.4 Inguinal and lower limb lymph nodes
0.007 0.993 0.000
C90.2 Plasmacytoma, extramedullary
0.000 0.993 0.007
C77.8 Lymph nodes of multiple regions
0.007 0.993 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.993 0.007
G36.9 Acute disseminated demyelination, unspecified
0.000 0.993 0.006
G36.8 Other specified acute disseminated demyelination
0.000 0.993 0.006
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.993 0.006
M81.40 Drug-induced osteoporosis (Multiple sites)
0.006 0.994 0.000
M25.58 Pain in joint (Other)
0.000 0.994 0.006
E66.1 Drug-induced obesity
0.000 0.994 0.006
G36.0 Neuromyelitis optica [Devic]
0.000 0.994 0.006
E65-E68 Obesity and other hyperalimentation
0.000 0.994 0.006
S64.3 Injury of digital nerve of thumb
0.006 0.994 0.001
N05.9 Unspecified
0.006 0.994 0.000
S60-S69 Injuries to the wrist and hand
0.006 0.994 0.000
R94.4 Abnormal results of kidney function studies
0.005 0.994 0.001
C77.9 Lymph node, unspecified
0.006 0.994 0.000
C77.1 Intrathoracic lymph nodes
0.006 0.994 0.000
D51 Vitamin B12 deficiency anaemia
0.000 0.994 0.006
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.994 0.006
D82 Immunodeficiency associated with other major defects
0.000 0.994 0.005
D81 Combined immunodeficiencies
0.000 0.994 0.005
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.995 0.005
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.995 0.005
D83 Common variable immunodeficiency
0.000 0.995 0.005
D50-D53 Nutritional anaemias
0.000 0.995 0.005
D55-D59 Haemolytic anaemias
0.000 0.995 0.005
S66 Injury of muscle and tendon at wrist and hand level
0.005 0.995 0.000
M25.57 Pain in joint (Ankle and foot)
0.000 0.995 0.005
C90.1 Plasma cell leukaemia
0.000 0.995 0.005
S68 Traumatic amputation of wrist and hand
0.005 0.995 0.000
E65 Localised adiposity
0.000 0.995 0.005
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.995 0.005
D84 Other immunodeficiencies
0.000 0.995 0.005
C77.5 Intrapelvic lymph nodes
0.005 0.995 0.000
E10.3 With ophthalmic complications
0.000 0.995 0.005
S66.8 Injury of other muscles and tendons at wrist and hand level
0.005 0.995 0.000
M25.52 Pain in joint (Upper arm)
0.000 0.995 0.005
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.005 0.995 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.005 0.995 0.000
M81.4 Drug-induced osteoporosis
0.005 0.995 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.005 0.995 0.000
D41.4 Bladder
0.005 0.995 0.000
C90.3 Solitary plasmacytoma
0.000 0.995 0.005
M25.50 Pain in joint (Multiple sites)
0.000 0.995 0.005
M25.56 Pain in joint (Lower leg)
0.000 0.995 0.005
E67 Other hyperalimentation
0.000 0.995 0.004
E68 Sequelae of hyperalimentation
0.000 0.995 0.004
S60 Superficial injury of wrist and hand
0.005 0.995 0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)
0.005 0.995 0.000
H40.2 Primary angle-closure glaucoma
0.005 0.995 0.000
E28.2 Polycystic ovarian syndrome
0.005 0.995 0.000
D53 Other nutritional anaemias
0.000 0.995 0.004
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.004 0.996 0.000
S68.0 Traumatic amputation of thumb (complete)(partial)
0.004 0.996 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.996 0.004
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.996 0.004
S60.8 Other superficial injuries of wrist and hand
0.004 0.996 0.000
D58 Other hereditary haemolytic anaemias
0.000 0.996 0.004
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.004 0.996 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.996 0.004
S65 Injury of blood vessels at wrist and hand level
0.004 0.996 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.996 0.004
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.996 0.004
D51.2 Transcobalamin II deficiency
0.000 0.996 0.004
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.996 0.004
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.996 0.004
D81.9 Combined immunodeficiency, unspecified
0.000 0.996 0.004
D81.8 Other combined immunodeficiencies
0.000 0.996 0.004
D81.7 Major histocompatibility complex class II deficiency
0.000 0.996 0.004
D81.6 Major histocompatibility complex class I deficiency
0.000 0.996 0.004
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.996 0.004
D81.4 Nezelof's syndrome
0.000 0.996 0.004
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.996 0.004
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.996 0.004
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.996 0.004
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.996 0.004
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.996 0.004
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.996 0.004
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.996 0.004
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.996 0.004
D82.2 Immunodeficiency with short-limbed stature
0.000 0.996 0.004
D82.1 Di George's syndrome
0.000 0.996 0.004
D82.0 Wiskott-Aldrich syndrome
0.000 0.996 0.004
K91.5 Postcholecystectomy syndrome
0.000 0.996 0.004
M81.49 Drug-induced osteoporosis (Site unspecified)
0.004 0.996 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.996 0.004
D89.3 Immune reconstitution syndrome
0.000 0.996 0.004
D89.1 Cryoglobulinaemia
0.000 0.996 0.004
K91.1 Postgastric surgery syndromes
0.000 0.996 0.004
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.004 0.996 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.001 0.996 0.004
D83.8 Other common variable immunodeficiencies
0.000 0.996 0.004
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.996 0.004
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.996 0.004
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.996 0.004
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.996 0.004
M25.53 Pain in joint (Forearm)
0.000 0.996 0.004
S60.9 Superficial injury of wrist and hand, unspecified
0.004 0.996 0.000
D59 Acquired haemolytic anaemia
0.000 0.996 0.004
S62.8 Fracture of other and unspecified parts of wrist and hand
0.004 0.996 0.000
E10.2 With renal complications
0.000 0.996 0.004
D57 Sickle-cell disorders
0.000 0.996 0.004
D55 Anaemia due to enzyme disorders
0.000 0.996 0.004
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.004 0.996 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.004 0.996 0.000
M25.77 Osteophyte (Ankle and foot)
0.000 0.996 0.004
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.996 0.004
D53.9 Nutritional anaemia, unspecified
0.000 0.996 0.004
D83.9 Common variable immunodeficiency, unspecified
0.000 0.996 0.004
N05 Unspecified nephritic syndrome
0.004 0.996 0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified
0.004 0.996 0.000
S68.8 Traumatic amputation of other parts of wrist and hand
0.004 0.996 0.000
S68.4 Traumatic amputation of hand at wrist level
0.004 0.996 0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand
0.004 0.996 0.000
L10-L14 Bullous disorders
0.000 0.996 0.004
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.000 0.996 0.004
E10 Insulin-dependent diabetes mellitus
0.000 0.996 0.004
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.004 0.996 0.000
D84.8 Other specified immunodeficiencies
0.000 0.996 0.004
D84.1 Defects in the complement system
0.000 0.996 0.004
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.996 0.004
D80 Immunodeficiency with predominantly antibody defects
0.000 0.996 0.004
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.996 0.004
C18.1 Appendix
0.004 0.996 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.000 0.996 0.004
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.004 0.996 0.000
S67 Crushing injury of wrist and hand
0.004 0.996 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.004 0.996 0.000
S63.3 Traumatic rupture of ligament of wrist and carpus
0.004 0.996 0.000
M81.48 Drug-induced osteoporosis (Other)
0.004 0.996 0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)
0.004 0.996 0.000
M81.46 Drug-induced osteoporosis (Lower leg)
0.004 0.996 0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)
0.004 0.996 0.000
M81.44 Drug-induced osteoporosis (Hand)
0.004 0.996 0.000
M81.43 Drug-induced osteoporosis (Forearm)
0.004 0.996 0.000
M81.42 Drug-induced osteoporosis (Upper arm)
0.004 0.996 0.000
M81.41 Drug-induced osteoporosis (Shoulder region)
0.004 0.996 0.000
S62 Fracture at wrist and hand level
0.004 0.996 0.000
E10.1 With ketoacidosis
0.000 0.996 0.004
S60.1 Contusion of finger(s) with damage to nail
0.004 0.996 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.004 0.996 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.004 0.996 0.000
E67.8 Other specified hyperalimentation
0.000 0.996 0.003
E67.3 Hypervitaminosis D
0.000 0.996 0.003
E67.2 Megavitamin-B6 syndrome
0.000 0.996 0.003
E67.1 Hypercarotenaemia
0.000 0.996 0.003
E67.0 Hypervitaminosis A
0.000 0.996 0.003
S63.5 Sprain and strain of wrist
0.003 0.996 0.000
D56 Thalassaemia
0.000 0.996 0.003
M25.7 Osteophyte
0.000 0.996 0.004
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.004 0.996 0.000
M25.71 Osteophyte (Shoulder region)
0.000 0.996 0.003
D53.8 Other specified nutritional anaemias
0.000 0.996 0.003
D53.2 Scorbutic anaemia
0.000 0.996 0.003
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.996 0.003
D53.0 Protein deficiency anaemia
0.000 0.996 0.003
S60.7 Multiple superficial injuries of wrist and hand
0.003 0.996 0.000
Q61.2 Polycystic kidney, adult type
0.000 0.997 0.003
S65.1 Injury of radial artery at wrist and hand level
0.003 0.997 0.000
L13 Other bullous disorders
0.000 0.997 0.003
S61.8 Open wound of other parts of wrist and hand
0.003 0.997 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.003 0.997 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.003 0.997 0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)
0.003 0.997 0.000
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.997 0.003
D58.2 Other haemoglobinopathies
0.000 0.997 0.003
D58.1 Hereditary elliptocytosis
0.000 0.997 0.003
S63.1 Dislocation finger
0.003 0.997 0.000
S63.7 Sprain and strain of other and unspecified parts of hand
0.003 0.997 0.000
S63.2 Multiple dislocations of fingers
0.003 0.997 0.000
S61 Open wound of wrist and hand
0.003 0.997 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.997 0.003
M25.9 Joint disorder, unspecified
0.000 0.997 0.003
S65.9 Injury of unspecified blood vessel at wrist and hand level
0.003 0.997 0.000
S65.8 Injury of other blood vessels at wrist and hand level
0.003 0.997 0.000
S65.7 Injury of multiple blood vessels at wrist and hand level
0.003 0.997 0.000
S65.4 Injury of blood vessel(s) of thumb
0.003 0.997 0.000
S65.3 Injury of deep palmar arch
0.003 0.997 0.000
S65.2 Injury of superficial palmar arch
0.003 0.997 0.000
M25 Other joint disorders, not elsewhere classified
0.000 0.997 0.003
S65.5 Injury of blood vessel(s) of other finger
0.003 0.997 0.000
M25.74 Osteophyte (Hand)
0.000 0.997 0.003
M87.9 Osteonecrosis, unspecified
0.003 0.997 0.000
C18.2 Ascending colon
0.003 0.997 0.000
C91.0 Acute lymphoblastic leukaemia
0.000 0.997 0.003
D84.9 Immunodeficiency, unspecified
0.000 0.997 0.003
L13.0 Dermatitis herpetiformis
0.000 0.997 0.003
C91 Lymphoid leukaemia
0.000 0.997 0.003
L11 Other acantholytic disorders
0.000 0.997 0.003
M25.96 Joint disorder, unspecified (Lower leg)
0.000 0.997 0.003
M87.96 Osteonecrosis, unspecified (Lower leg)
0.003 0.997 0.000
E10.5 With peripheral circulatory complications
0.000 0.997 0.003
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.003 0.997 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.000 0.997 0.003
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.997 0.003
D59.8 Other acquired haemolytic anaemias
0.000 0.997 0.003
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.997 0.003
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.997 0.003
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.997 0.003
D59.3 Haemolytic-uraemic syndrome
0.000 0.997 0.003
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.997 0.003
D59.1 Other autoimmune haemolytic anaemias
0.000 0.997 0.003
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.997 0.003
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.997 0.003
S62.81 Fracture of other and unspecified parts of wrist and hand (open)
0.003 0.997 0.000
N05.2 Diffuse membranous glomerulonephritis
0.003 0.997 0.000
S69 Other and unspecified injuries of wrist and hand
0.003 0.997 0.000
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.997 0.003
D55.8 Other anaemias due to enzyme disorders
0.000 0.997 0.003
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.997 0.003
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.997 0.003
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.997 0.003
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.997 0.003
D57.8 Other sickle-cell disorders
0.000 0.997 0.003
D57.3 Sickle-cell trait
0.000 0.997 0.003
D57.2 Double heterozygous sickling disorders
0.000 0.997 0.003
D57.1 Sickle-cell anaemia without crisis
0.000 0.997 0.003
D57.0 Sickle-cell anaemia with crisis
0.000 0.997 0.003
D58.0 Hereditary spherocytosis
0.000 0.997 0.003
S60.0 Contusion of finger(s) without damage to nail
0.003 0.997 0.000
C18.7 Sigmoid colon
0.003 0.997 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.003 0.997 0.000
C18 Malignant neoplasm of colon
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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